PMC:4428493 / 20978-21843
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4428493","sourcedb":"PMC","sourceid":"4428493","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4428493","text":"In three studies using a nutrition and lifestyle intervention, brain activation at the commencement of the intervention was associated with degree of weight-loss success and maintenance. This included areas associated with reward processing and anticipation [insula, anterior cingulate cortex, nucleus accumbens (55), and the OFC (56)], decision making [PFC (54) and OFC (56)], and impulsivity [nucleus accumbens and the anterior cingulate cortex (55)]. Participants who had successfully lost and maintained weight-loss displayed differential neural responses to food cues to those of healthy weight participants in areas involved in emotion, memory, and visual processing [cingulate gyrus, parietal cortex (51)], and to that of obese participants in regions associated with emotion, impulse control, and reward-based learning [PFC and the anterior cingulate (50)].","tracks":[{"project":"0_colil","denotations":[{"id":"25988110-22332246-908648","span":{"begin":313,"end":315},"obj":"22332246"},{"id":"25988110-22731395-908649","span":{"begin":331,"end":333},"obj":"22731395"},{"id":"25988110-23867558-908650","span":{"begin":359,"end":361},"obj":"23867558"},{"id":"25988110-22731395-908651","span":{"begin":372,"end":374},"obj":"22731395"},{"id":"25988110-22332246-908652","span":{"begin":448,"end":450},"obj":"22332246"},{"id":"25988110-21633398-908653","span":{"begin":708,"end":710},"obj":"21633398"},{"id":"25988110-19675107-908654","span":{"begin":860,"end":862},"obj":"19675107"}],"attributes":[{"subj":"25988110-22332246-908648","pred":"source","obj":"0_colil"},{"subj":"25988110-22731395-908649","pred":"source","obj":"0_colil"},{"subj":"25988110-23867558-908650","pred":"source","obj":"0_colil"},{"subj":"25988110-22731395-908651","pred":"source","obj":"0_colil"},{"subj":"25988110-22332246-908652","pred":"source","obj":"0_colil"},{"subj":"25988110-21633398-908653","pred":"source","obj":"0_colil"},{"subj":"25988110-19675107-908654","pred":"source","obj":"0_colil"}]},{"project":"2_test","denotations":[{"id":"25988110-22332246-38724575","span":{"begin":313,"end":315},"obj":"22332246"},{"id":"25988110-22731395-38724576","span":{"begin":331,"end":333},"obj":"22731395"},{"id":"25988110-23867558-38724577","span":{"begin":359,"end":361},"obj":"23867558"},{"id":"25988110-22731395-38724578","span":{"begin":372,"end":374},"obj":"22731395"},{"id":"25988110-22332246-38724579","span":{"begin":448,"end":450},"obj":"22332246"},{"id":"25988110-21633398-38724580","span":{"begin":708,"end":710},"obj":"21633398"},{"id":"25988110-19675107-38724581","span":{"begin":860,"end":862},"obj":"19675107"}],"attributes":[{"subj":"25988110-22332246-38724575","pred":"source","obj":"2_test"},{"subj":"25988110-22731395-38724576","pred":"source","obj":"2_test"},{"subj":"25988110-23867558-38724577","pred":"source","obj":"2_test"},{"subj":"25988110-22731395-38724578","pred":"source","obj":"2_test"},{"subj":"25988110-22332246-38724579","pred":"source","obj":"2_test"},{"subj":"25988110-21633398-38724580","pred":"source","obj":"2_test"},{"subj":"25988110-19675107-38724581","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"0_colil","color":"#eca693","default":true},{"id":"2_test","color":"#9399ec"}]}]}}