PMC:441373 / 34029-34717
Annnotations
craft-sa-dev
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craft-ca-core-ex-dev
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craft-ca-core-dev
{"project":"craft-ca-core-dev","denotations":[{"id":"T8092","span":{"begin":29,"end":39},"obj":"NCBITaxon:7742"},{"id":"T8093","span":{"begin":226,"end":236},"obj":"NCBITaxon:7742"},{"id":"T8094","span":{"begin":339,"end":349},"obj":"GO:0005813"},{"id":"T8095","span":{"begin":350,"end":357},"obj":"GO:0007067"},{"id":"T8096","span":{"begin":350,"end":365},"obj":"GO:0072686"},{"id":"T8097","span":{"begin":404,"end":408},"obj":"SO:0000704"},{"id":"T8098","span":{"begin":409,"end":419},"obj":"GO:0065007"},{"id":"T8099","span":{"begin":473,"end":487},"obj":"GO:0006396"},{"id":"T8100","span":{"begin":492,"end":503},"obj":"GO:0006412"},{"id":"T8101","span":{"begin":659,"end":674},"obj":"GO:0043234"}],"text":"The interaction data for the vertebrate TACCs is relatively limited; however, interaction networks are now beginning to emerge. The results of our functional analysis, as well as other published data clearly indicate that the vertebrate TACCs interact with proteins that can be divided into two broad categories: 1) proteins with roles in centrosome/mitotic spindle dynamics, and 2) proteins involved in gene regulation, either at the level of transcription, or subsequent RNA processing and translation [3,5-7,15,19-21,24,25,33,34]. Many of these proteins do not appear to interact directly with the protostome TACCs, but would be expected to be in the same protein complex (Fig. 6C,6D)."}
2_test
{"project":"2_test","denotations":[{"id":"15207008-12620397-9666042","span":{"begin":505,"end":506},"obj":"12620397"},{"id":"15207008-12956952-9666043","span":{"begin":507,"end":508},"obj":"12956952"},{"id":"15207008-12956951-9666043","span":{"begin":507,"end":508},"obj":"12956951"},{"id":"15207008-11025203-9666043","span":{"begin":507,"end":508},"obj":"11025203"},{"id":"15207008-11903063-9666044","span":{"begin":511,"end":513},"obj":"11903063"},{"id":"15207008-12165861-9666045","span":{"begin":514,"end":516},"obj":"12165861"},{"id":"15207008-14603251-9666045","span":{"begin":514,"end":516},"obj":"14603251"},{"id":"15207008-14602875-9666045","span":{"begin":514,"end":516},"obj":"14602875"},{"id":"15207008-11433296-9666046","span":{"begin":520,"end":522},"obj":"11433296"},{"id":"15207008-11827981-9666047","span":{"begin":523,"end":525},"obj":"11827981"},{"id":"15207008-11847113-9666048","span":{"begin":526,"end":528},"obj":"11847113"},{"id":"15207008-14767476-9666049","span":{"begin":529,"end":531},"obj":"14767476"}],"text":"The interaction data for the vertebrate TACCs is relatively limited; however, interaction networks are now beginning to emerge. The results of our functional analysis, as well as other published data clearly indicate that the vertebrate TACCs interact with proteins that can be divided into two broad categories: 1) proteins with roles in centrosome/mitotic spindle dynamics, and 2) proteins involved in gene regulation, either at the level of transcription, or subsequent RNA processing and translation [3,5-7,15,19-21,24,25,33,34]. Many of these proteins do not appear to interact directly with the protostome TACCs, but would be expected to be in the same protein complex (Fig. 6C,6D)."}