PMC:4331676 / 11837-12406 JSONTXT

{"project":"2_test","denotations":[{"id":"25708928-17237066-14842649","span":{"begin":171,"end":173},"obj":"17237066"},{"id":"25708928-19908123-14842649","span":{"begin":171,"end":173},"obj":"19908123"},{"id":"25708928-22272076-14842649","span":{"begin":171,"end":173},"obj":"22272076"},{"id":"25708928-11452024-14842650","span":{"begin":308,"end":310},"obj":"11452024"}],"text":"Evolutionary information, one of the most import kinds of information in protein functionality annotation in biological analysis, has been widely used in many studies [21,60-63]. In this study, evolutionary information in forms of PSSM profile of every protein sequence is obtained by running the PSI-BLAST [64] program to search the non-redundant (NR) database through three iteration with 0.001 as the E-value cutoff for multiple sequence alignment. The final PSSM profile is a matrix with dimension of L*20 (excluding dummy residue X), which can depicted as follows:"}