PMC:4307189 / 56458-58859 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4307189","sourcedb":"PMC","sourceid":"4307189","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4307189","text":"Additional files\nAdditional file 1 Appendix I. Derivation of p 1-model for directed network.\nAdditional file 2 Table S1. All 11,515 drug-resistant gene-pairs found in GSE38376.\nAdditional file 3 Table S2. All 1,083 (841 distinct) cross-talks found between EGFR and other 23 signaling pathways from Reactome database.\nAdditional file 4 Table S3. All 2,179 (1,050 distinct) cross-talks found between ErbB and other 34 signaling pathways from KEGG database.\nAdditional file 5 Table S4. All 3,084 (876 distinct) cross-talks found between ErbB and other 62 signaling pathways from WikiPathway database.\nAdditional file 6 Table S5. 104 drug-resistant cross-talks found between EGFR and other 23 signaling pathways from Reactome database [GSE38376].\nAdditional file 7 Table S6. 188 drug-resistant cross-talks found between ErbB and other 34 signaling pathways from KEGG database [GSE38376].\nAdditional file 8 Table S7. 299 drug-resistant cross-talks found between ErbB and other 62 signaling pathways from WikiPathway database [GSE38376].\nAdditional file 9 Table S8. 168 selected cross-talks which associated EGFR (or ErbB) signaling pathways with 6 other signaling pathways that were found in at least two different pathway analyses (i.e. Reactome and KEGG, or KEGG and WikiPathway, or Reactome and WikiPathway) [GSE38376].\nAdditional file 10 Table S9. All 10,811 drug-resistant gene-pairs found in GSE16179.\nAdditional file 11 Table S10. 83 drug-resistant cross-talks found between EGFR and other 23 signaling pathways from Reactome database [GSE16179].\nAdditional file 12 Table S11. 133 drug-resistant cross-talks found between ErbB and other 34 signaling pathways from KEGG database [GSE16179].\nAdditional file 13 Table S12. 278 drug-resistant cross-talks found between ErbB and other 62 signaling pathways from WikiPathway database [GSE16179].\nAdditional file 14 Table S13. 86 drug-resistant cross-talks found in all Reactome, KEGG and WikiPathway analyses where both genes in a particular cross-talk was up-regulated in resistant conditions but down-regulated in parental conditions [GSE16179].\nAdditional file 15 Table S14. 401 cross-talks from Reactome, KEGG and WikiPathway analyses where the genes are dysregulated in parental treatment vs parental basal condition, and reversely changed in resistant basal + resistant treatment vs parental basal condition [GSE16179].","divisions":[{"label":"title","span":{"begin":0,"end":16}},{"label":"p","span":{"begin":17,"end":94}},{"label":"label","span":{"begin":17,"end":34}},{"label":"caption","span":{"begin":36,"end":94}},{"label":"p","span":{"begin":36,"end":94}},{"label":"p","span":{"begin":95,"end":180}},{"label":"label","span":{"begin":95,"end":112}},{"label":"caption","span":{"begin":114,"end":180}},{"label":"p","span":{"begin":114,"end":180}},{"label":"p","span":{"begin":181,"end":322}},{"label":"label","span":{"begin":181,"end":198}},{"label":"caption","span":{"begin":200,"end":322}},{"label":"p","span":{"begin":200,"end":322}},{"label":"p","span":{"begin":323,"end":462}},{"label":"label","span":{"begin":323,"end":340}},{"label":"caption","span":{"begin":342,"end":462}},{"label":"p","span":{"begin":342,"end":462}},{"label":"p","span":{"begin":463,"end":607}},{"label":"label","span":{"begin":463,"end":480}},{"label":"caption","span":{"begin":482,"end":607}},{"label":"p","span":{"begin":482,"end":607}},{"label":"p","span":{"begin":608,"end":754}},{"label":"label","span":{"begin":608,"end":625}},{"label":"caption","span":{"begin":627,"end":754}},{"label":"p","span":{"begin":627,"end":754}},{"label":"p","span":{"begin":755,"end":897}},{"label":"label","span":{"begin":755,"end":772}},{"label":"caption","span":{"begin":774,"end":897}},{"label":"p","span":{"begin":774,"end":897}},{"label":"p","span":{"begin":898,"end":1047}},{"label":"label","span":{"begin":898,"end":915}},{"label":"caption","span":{"begin":917,"end":1047}},{"label":"p","span":{"begin":917,"end":1047}},{"label":"p","span":{"begin":1048,"end":1335}},{"label":"label","span":{"begin":1048,"end":1065}},{"label":"caption","span":{"begin":1067,"end":1335}},{"label":"p","span":{"begin":1067,"end":1335}},{"label":"p","span":{"begin":1336,"end":1422}},{"label":"label","span":{"begin":1336,"end":1354}},{"label":"caption","span":{"begin":1356,"end":1422}},{"label":"p","span":{"begin":1356,"end":1422}},{"label":"p","span":{"begin":1423,"end":1570}},{"label":"label","span":{"begin":1423,"end":1441}},{"label":"caption","span":{"begin":1443,"end":1570}},{"label":"p","span":{"begin":1443,"end":1570}},{"label":"p","span":{"begin":1571,"end":1715}},{"label":"label","span":{"begin":1571,"end":1589}},{"label":"caption","span":{"begin":1591,"end":1715}},{"label":"p","span":{"begin":1591,"end":1715}},{"label":"p","span":{"begin":1716,"end":1867}},{"label":"label","span":{"begin":1716,"end":1734}},{"label":"caption","span":{"begin":1736,"end":1867}},{"label":"p","span":{"begin":1736,"end":1867}},{"label":"p","span":{"begin":1868,"end":2121}},{"label":"label","span":{"begin":1868,"end":1886}},{"label":"caption","span":{"begin":1888,"end":2121}},{"label":"p","span":{"begin":1888,"end":2121}},{"label":"label","span":{"begin":2122,"end":2140}}],"tracks":[]}