PMC:4307189 / 47054-48393 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4307189","sourcedb":"PMC","sourceid":"4307189","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4307189","text":"Table 3 Comparative results between primary dataset (SKBR3 cell-line, GSE38376) and validation dataset (BT474 cell-line, GSE16179)\nPathway name Found in Pathway source Found in Pathway source Common cross-talks in both Studies ¶\n(GSE38376) (GSE16179)\nNotch Signaling Reactome, Reactome, MAP2K4::NOTCH1\nKEGG, KEGG,\nWikiPathway WikiPathway\nGPCR signaling Reactome, Reactome, CBL::TSHR\nWikiPathway WikiPathway FGFR1::TSHR\nPDGFRA::GNAQ\nKIT::TSHR\nLCK::TSHR\nMDM2::TSHR\nPDGFRA::TSHR\nWNT Signaling Reactome, Reactome, AKT2::CCND2\nKEGG, KEGG, MAP2K4::CCND2\nWikiPathway WikiPathway MAP2K4::TP53\nMDM2::MAP2K4\nInsulin (IGF1R) Signaling Reactome, Reactome, MDM2::MAP2K4\nWikiPathway WikiPathway TP53::MAP2K4\nTGF- β Signaling Reactome, Reactome, MDM2::TFE3\nWikiPathway KEGG, TP53::TFE3\nWikiPathway\nMAPK signaling KEGG, KEGG, MDM2::MAP2K4\nWikiPathway WikiPathway\n¶These common cross-talks were found using the primary dataset (104, 188 and 299 cross-talks from Reactome, KEGG and WikiPathway databases, respectively) and validation datasets (83, 133 and 277 cross-talks from Reactome, KEGG and WikiPathway databases, respectively). Cross-talks mentioned with Bold face are those consistent with our hypothesis that both genes in the particular cross-talk are up-regulated in resistant conditions but down-regulated in parental conditions.\n","divisions":[{"label":"label","span":{"begin":0,"end":7}},{"label":"caption","span":{"begin":8,"end":131}},{"label":"p","span":{"begin":8,"end":131}},{"label":"table","span":{"begin":132,"end":862}},{"label":"tr","span":{"begin":132,"end":233}},{"label":"th","span":{"begin":132,"end":145}},{"label":"th","span":{"begin":145,"end":169}},{"label":"th","span":{"begin":170,"end":194}},{"label":"th","span":{"begin":195,"end":233}},{"label":"tr","span":{"begin":234,"end":256}},{"label":"th","span":{"begin":234,"end":245}},{"label":"th","span":{"begin":245,"end":256}},{"label":"tr","span":{"begin":257,"end":308}},{"label":"td","span":{"begin":257,"end":272}},{"label":"td","span":{"begin":273,"end":282}},{"label":"td","span":{"begin":283,"end":292}},{"label":"td","span":{"begin":293,"end":308}},{"label":"tr","span":{"begin":309,"end":320}},{"label":"td","span":{"begin":309,"end":314}},{"label":"td","span":{"begin":315,"end":320}},{"label":"tr","span":{"begin":321,"end":344}},{"label":"td","span":{"begin":321,"end":332}},{"label":"td","span":{"begin":333,"end":344}},{"label":"tr","span":{"begin":345,"end":390}},{"label":"td","span":{"begin":345,"end":359}},{"label":"td","span":{"begin":360,"end":369}},{"label":"td","span":{"begin":370,"end":379}},{"label":"td","span":{"begin":380,"end":390}},{"label":"tr","span":{"begin":391,"end":427}},{"label":"td","span":{"begin":391,"end":402}},{"label":"td","span":{"begin":403,"end":414}},{"label":"td","span":{"begin":415,"end":427}},{"label":"tr","span":{"begin":428,"end":441}},{"label":"td","span":{"begin":428,"end":441}},{"label":"tr","span":{"begin":441,"end":451}},{"label":"td","span":{"begin":441,"end":451}},{"label":"tr","span":{"begin":451,"end":461}},{"label":"td","span":{"begin":451,"end":461}},{"label":"tr","span":{"begin":461,"end":472}},{"label":"td","span":{"begin":461,"end":472}},{"label":"tr","span":{"begin":472,"end":485}},{"label":"td","span":{"begin":472,"end":485}},{"label":"tr","span":{"begin":485,"end":531}},{"label":"td","span":{"begin":485,"end":498}},{"label":"td","span":{"begin":499,"end":508}},{"label":"td","span":{"begin":509,"end":518}},{"label":"td","span":{"begin":519,"end":531}},{"label":"tr","span":{"begin":532,"end":558}},{"label":"td","span":{"begin":532,"end":537}},{"label":"td","span":{"begin":538,"end":543}},{"label":"td","span":{"begin":544,"end":558}},{"label":"tr","span":{"begin":559,"end":596}},{"label":"td","span":{"begin":559,"end":570}},{"label":"td","span":{"begin":571,"end":582}},{"label":"td","span":{"begin":583,"end":596}},{"label":"tr","span":{"begin":597,"end":610}},{"label":"td","span":{"begin":597,"end":610}},{"label":"tr","span":{"begin":610,"end":669}},{"label":"td","span":{"begin":610,"end":635}},{"label":"td","span":{"begin":636,"end":645}},{"label":"td","span":{"begin":646,"end":655}},{"label":"td","span":{"begin":656,"end":669}},{"label":"tr","span":{"begin":670,"end":707}},{"label":"td","span":{"begin":670,"end":681}},{"label":"td","span":{"begin":682,"end":693}},{"label":"td","span":{"begin":694,"end":707}},{"label":"tr","span":{"begin":708,"end":756}},{"label":"td","span":{"begin":708,"end":724}},{"label":"td","span":{"begin":725,"end":734}},{"label":"td","span":{"begin":735,"end":744}},{"label":"td","span":{"begin":745,"end":756}},{"label":"tr","span":{"begin":757,"end":786}},{"label":"td","span":{"begin":757,"end":768}},{"label":"td","span":{"begin":769,"end":774}},{"label":"td","span":{"begin":775,"end":786}},{"label":"tr","span":{"begin":787,"end":798}},{"label":"td","span":{"begin":787,"end":798}},{"label":"tr","span":{"begin":799,"end":838}},{"label":"td","span":{"begin":799,"end":813}},{"label":"td","span":{"begin":814,"end":819}},{"label":"td","span":{"begin":820,"end":825}},{"label":"td","span":{"begin":826,"end":838}},{"label":"tr","span":{"begin":839,"end":862}},{"label":"td","span":{"begin":839,"end":850}},{"label":"td","span":{"begin":851,"end":862}}],"tracks":[]}