PMC:4143611 / 11196-11865 JSONTXT

{"project":"2_test","denotations":[{"id":"24980037-21367932-63233432","span":{"begin":302,"end":304},"obj":"21367932"},{"id":"24980037-20375210-63233433","span":{"begin":665,"end":667},"obj":"20375210"}],"text":"Somatic consequences of mild hypercortisolemia may be subtle or subclinical, but over time will be additive and inexorable. Evidence implies that patients may develop complications associated with long-term exposure to hypercortisolemia, such as diabetes mellitus, metabolic disturbances, and obesity [38]. More importantly, patients with SCS caused by hormonally active adrenal tumors may exhibit slow, long-term progression of these symptoms if not surgically treated. A retrospective study involving \u003e100 patients suggested that treating SCS by means of laparoscopic adrenalectomy may improve blood pressure control, weight control, and carbohydrate metabolism [39]."}