PMC:3813744 / 22968-24061 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/3813744","sourcedb":"PMC","sourceid":"3813744","source_url":"http://www.ncbi.nlm.nih.gov/pmc/3813744","text":"10.1371/journal.pone.0077762.g002 Figure 2 Performance in the full reversal, perseverance and learned non-reward tests in the SB242084 (a–b) and 5-HT2CR KO experiments (c–d).\nAsterisk denote differences at which p\u003c.05. (a) Significant main effect of test (F2,61 = 13.10, p\u003c.0001) and a near significant drug × test interactions (F2, 61 = 3.13, p = .051) on trials to criterion. SB242084 decreased trials to criterion in the perseverance test (F1,20 = 4.54, p = .046) and increased trials to criterion in the learned non-reward test (F1,22 = 4.44, p = .047). (b) Significant main effects of test condition (F2, 61 = 9.65, p\u003c.0001) and drug × test interactions (F2, 61 = 3.46, p = .037) on incorrect responses to criterion. SB242084 decreased incorrect responses to criterion in the perseverance test (F1,20 = 5.96, p = .024). (c-d) Significant main effects of genotype on trials (F1,26 = 5.83, p = .023) and incorrect responses (F1,26 = 4.45, p\u003c.045) to criterion in the perseverance test. Genotype had no significant effects on performance in the full reversal and learned non-reward tests. ","divisions":[{"label":"Title","span":{"begin":44,"end":175}}],"tracks":[]}