PMC:3807239 / 27320-28080 JSONTXT

{"project":"2_test","denotations":[{"id":"24163754-21347261-69479711","span":{"begin":744,"end":746},"obj":"21347261"},{"id":"24163754-21347261-69479711","span":{"begin":744,"end":746},"obj":"21347261"},{"id":"24163754-22655055-69479712","span":{"begin":747,"end":749},"obj":"22655055"},{"id":"24163754-22655055-69479712","span":{"begin":747,"end":749},"obj":"22655055"},{"id":"24163754-21498399-69479713","span":{"begin":750,"end":752},"obj":"21498399"},{"id":"24163754-21498399-69479713","span":{"begin":750,"end":752},"obj":"21498399"},{"id":"24163754-17698639-69479714","span":{"begin":753,"end":755},"obj":"17698639"},{"id":"24163754-17698639-69479714","span":{"begin":753,"end":755},"obj":"17698639"},{"id":"24163754-19920113-69479715","span":{"begin":756,"end":758},"obj":"19920113"},{"id":"24163754-19920113-69479715","span":{"begin":756,"end":758},"obj":"19920113"},{"id":"T22522","span":{"begin":744,"end":746},"obj":"21347261"},{"id":"T48115","span":{"begin":744,"end":746},"obj":"21347261"},{"id":"T65917","span":{"begin":747,"end":749},"obj":"22655055"},{"id":"T75404","span":{"begin":747,"end":749},"obj":"22655055"},{"id":"T45041","span":{"begin":750,"end":752},"obj":"21498399"},{"id":"T3864","span":{"begin":750,"end":752},"obj":"21498399"},{"id":"T31200","span":{"begin":753,"end":755},"obj":"17698639"},{"id":"T74901","span":{"begin":753,"end":755},"obj":"17698639"},{"id":"T52267","span":{"begin":756,"end":758},"obj":"19920113"},{"id":"T75736","span":{"begin":756,"end":758},"obj":"19920113"}],"text":"6.2. Osterosarcoma Xenograft Specimens\nTen human osterosarcoma xenograft specimens were collected, and each was treated with saline (as control) and three chemotherapeutic treatments: cisplatin (CIS), doxorubicin (DOX) and ifosfamide (IFO). The total RNAs were isolated from each sample and analyzed with the following three platforms: (a) miRCURY LNA MicroRNA Array (Exiqon Inc.; Vedbaek, Denmark, based on miRbase 9.2); (b) Luminex FlexmiR MicroRNA Human Panel; and (c) TaqMan Array Human MicroRNA Panel (Applied Biosystems,Foster City, CA, USA, v2.0). A total of 577 human miRNAs were profiled with the LNA array, 391 with the Luminex bead array and 664 with the TaqMan array, where a total of 213 miRNAs were shared by all three platforms [37,40,41,58,59]."}