PMC:3727638 / 32768-33672 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/3727638","sourcedb":"PMC","sourceid":"3727638","source_url":"https://www.ncbi.nlm.nih.gov/pmc/3727638","text":"For the NIH MEN1/ZES patients, 24 of the 106 (23%) patients died during follow-up, which averaged 15.5 ± 0.9 years (range, 1–44 yr) from diagnosis of MEN1 (Figure 1). The general characteristics of the 24 deceased patients were similar to those of all the NIH patients (see Table 1). These 24 NIH MEN1/ZES patients had both similarities to and differences from the 227 MEN1/PET patients from the pooled literature. They were similar in all having a PET, in having a high frequency of HPT (95%–96%), in the rates of thymic carcinoids (12.5%–13.3%), and in the frequency of non-ZES functional PETs (21%–23%), CNS tumors (0.5%–4.2%), or smooth muscle tumors (0–0.9%), and some skin tumors (melanomas, lipomas) (0.5%–4.6%). The patients were also similar in the high frequency of a family history of MEN1, in having a slight male predominance (58–61%), and in their mean age at last follow-up (51.6–55.1 yr).","tracks":[]}