PMC:3724972 / 20346-21231
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/3724972","sourcedb":"PMC","sourceid":"3724972","source_url":"https://www.ncbi.nlm.nih.gov/pmc/3724972","text":"Compound Trial Patients (N) Treatment duration Outcome\nPasireotide Boscaro et al. [40] 29 15 days 5/29 patients (17 %) achieved UFC ≤ ULN; 22/29 patients (76 %) experienced reduction in mean UFC\nColao et al. [43] 162 12 months 33/162 patients (20 %) achieved UFC ≤ ULN within 6 months without increase from randomized dose; the majority of patients experienced reduction in UFC at month 6, sustained through month 12\nCabergoline Lila et al. [52] 18 5 months 5 patients (28 %) achieved MNSC \u003c5 μg/dL or low-dose dexamethasone-suppressed serum cortisol \u003c1.8 μg/dL\nPivonello et al. [48, 53] 20 3–24 months After 3 months, 15 patients (75 %) achieved UFC ≤ ULN or ≥25 % reduction from baseline; 8 patients (40 %) maintained UFC ≤ ULN at 24 months\nRetinoic acid Pecori Girald et al. [59] 7 6–12 months 3/7 patients (43 %) achieved UFC ≤ ULN; 5/7 patients (71 %) experienced reduction in UFC","divisions":[{"label":"tr","span":{"begin":0,"end":54}},{"label":"th","span":{"begin":0,"end":8}},{"label":"th","span":{"begin":9,"end":14}},{"label":"th","span":{"begin":15,"end":27}},{"label":"th","span":{"begin":28,"end":46}},{"label":"th","span":{"begin":47,"end":54}},{"label":"tr","span":{"begin":55,"end":194}},{"label":"td","span":{"begin":55,"end":66}},{"label":"td","span":{"begin":67,"end":86}},{"label":"td","span":{"begin":87,"end":89}},{"label":"td","span":{"begin":90,"end":97}},{"label":"td","span":{"begin":98,"end":194}},{"label":"tr","span":{"begin":195,"end":416}},{"label":"td","span":{"begin":195,"end":212}},{"label":"td","span":{"begin":213,"end":216}},{"label":"td","span":{"begin":217,"end":226}},{"label":"td","span":{"begin":227,"end":416}},{"label":"tr","span":{"begin":417,"end":561}},{"label":"td","span":{"begin":417,"end":428}},{"label":"td","span":{"begin":429,"end":445}},{"label":"td","span":{"begin":446,"end":448}},{"label":"td","span":{"begin":449,"end":457}},{"label":"td","span":{"begin":458,"end":561}},{"label":"tr","span":{"begin":562,"end":742}},{"label":"td","span":{"begin":562,"end":587}},{"label":"td","span":{"begin":588,"end":590}},{"label":"td","span":{"begin":591,"end":602}},{"label":"td","span":{"begin":603,"end":742}},{"label":"td","span":{"begin":743,"end":756}},{"label":"td","span":{"begin":757,"end":782}},{"label":"td","span":{"begin":783,"end":784}},{"label":"td","span":{"begin":785,"end":796}}],"tracks":[{"project":"2_test","denotations":[{"id":"23673515-18957506-63233650","span":{"begin":83,"end":85},"obj":"18957506"},{"id":"23673515-22397653-63233651","span":{"begin":209,"end":211},"obj":"22397653"},{"id":"23673515-20497937-63233652","span":{"begin":442,"end":444},"obj":"20497937"},{"id":"23673515-15126577-63233653","span":{"begin":580,"end":582},"obj":"15126577"},{"id":"23673515-18957500-63233654","span":{"begin":584,"end":586},"obj":"18957500"},{"id":"23673515-22851491-63233655","span":{"begin":779,"end":781},"obj":"22851491"}],"attributes":[{"subj":"23673515-18957506-63233650","pred":"source","obj":"2_test"},{"subj":"23673515-22397653-63233651","pred":"source","obj":"2_test"},{"subj":"23673515-20497937-63233652","pred":"source","obj":"2_test"},{"subj":"23673515-15126577-63233653","pred":"source","obj":"2_test"},{"subj":"23673515-18957500-63233654","pred":"source","obj":"2_test"},{"subj":"23673515-22851491-63233655","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#93ec9d","default":true}]}]}}