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{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T2114","span":{"begin":379,"end":387},"obj":"http://www.uniprot.org/uniprot/P05120"},{"id":"T2113","span":{"begin":234,"end":242},"obj":"http://www.uniprot.org/uniprot/P05120"},{"id":"T2112","span":{"begin":45,"end":53},"obj":"http://www.uniprot.org/uniprot/P05120"},{"id":"T2130","span":{"begin":168,"end":173},"obj":"http://www.uniprot.org/uniprot/P01579"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"Our previously published data indicated that SerpinB2 is distinctly regulated from other LPS-inducible genes in terms of kinetics, LPS dose response and sensitivity to IFN-γ co-stimulation [4]; however, the cis-acting elements in the SerpinB2 promoter responsible for LPS-dependent transcription in macrophages and the specific LPS-responsive transcription factors that bind the SerpinB2 promoter were not defined."}

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{"project":"BioNLP16_Messiy","denotations":[{"id":"T2228","span":{"begin":45,"end":53},"obj":"Protein"},{"id":"T2231","span":{"begin":379,"end":387},"obj":"Protein"},{"id":"T2230","span":{"begin":234,"end":242},"obj":"Protein"},{"id":"T2229","span":{"begin":168,"end":173},"obj":"Protein"},{"id":"T2250","span":{"begin":68,"end":77},"obj":"Regulation"},{"id":"T2249","span":{"begin":370,"end":374},"obj":"Binding"}],"relations":[{"id":"R1514","pred":"themeOf","subj":"T2231","obj":"T2249"},{"id":"R1518","pred":"themeOf","subj":"T2228","obj":"T2250"}],"text":"Our previously published data indicated that SerpinB2 is distinctly regulated from other LPS-inducible genes in terms of kinetics, LPS dose response and sensitivity to IFN-γ co-stimulation [4]; however, the cis-acting elements in the SerpinB2 promoter responsible for LPS-dependent transcription in macrophages and the specific LPS-responsive transcription factors that bind the SerpinB2 promoter were not defined."}

{"project":"DLUT931","denotations":[{"id":"T2170","span":{"begin":370,"end":374},"obj":"Binding"},{"id":"T2169","span":{"begin":68,"end":77},"obj":"Regulation"},{"id":"T2150","span":{"begin":379,"end":387},"obj":"Protein"},{"id":"T2149","span":{"begin":234,"end":242},"obj":"Protein"},{"id":"T2148","span":{"begin":168,"end":173},"obj":"Protein"},{"id":"T2147","span":{"begin":45,"end":53},"obj":"Protein"}],"relations":[{"id":"R1484","pred":"themeOf","subj":"T2147","obj":"T2169"},{"id":"R1485","pred":"themeOf","subj":"T2150","obj":"T2170"}],"text":"Our previously published data indicated that SerpinB2 is distinctly regulated from other LPS-inducible genes in terms of kinetics, LPS dose response and sensitivity to IFN-γ co-stimulation [4]; however, the cis-acting elements in the SerpinB2 promoter responsible for LPS-dependent transcription in macrophages and the specific LPS-responsive transcription factors that bind the SerpinB2 promoter were not defined."}

{"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T2483","span":{"begin":168,"end":192},"obj":"Positive_regulation"},{"id":"T2481","span":{"begin":264,"end":295},"obj":"Regulation"},{"id":"T2461","span":{"begin":268,"end":281},"obj":"Entity"},{"id":"T2443","span":{"begin":379,"end":387},"obj":"Protein"},{"id":"T2439","span":{"begin":230,"end":295},"obj":"Entity"},{"id":"T2433","span":{"begin":83,"end":108},"obj":"Protein"},{"id":"T2431","span":{"begin":375,"end":396},"obj":"Entity"},{"id":"T2429","span":{"begin":234,"end":242},"obj":"Protein"},{"id":"T2410","span":{"begin":45,"end":67},"obj":"Protein"},{"id":"T2406","span":{"begin":168,"end":173},"obj":"Protein"},{"id":"T2402","span":{"begin":328,"end":331},"obj":"Entity"},{"id":"T2383","span":{"begin":299,"end":310},"obj":"Entity"},{"id":"T2380","span":{"begin":131,"end":134},"obj":"Entity"}],"relations":[{"id":"R1599","pred":"causeOf","subj":"T2461","obj":"T2481"},{"id":"R1613","pred":"themeOf","subj":"T2406","obj":"T2483"},{"id":"R1630","pred":"partOf","subj":"T2431","obj":"T2443"},{"id":"R1636","pred":"partOf","subj":"T2439","obj":"T2429"}],"text":"Our previously published data indicated that SerpinB2 is distinctly regulated from other LPS-inducible genes in terms of kinetics, LPS dose response and sensitivity to IFN-γ co-stimulation [4]; however, the cis-acting elements in the SerpinB2 promoter responsible for LPS-dependent transcription in macrophages and the specific LPS-responsive transcription factors that bind the SerpinB2 promoter were not defined."}

{"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T2302","span":{"begin":252,"end":263},"obj":"Regulation"},{"id":"T2301","span":{"begin":370,"end":374},"obj":"Binding"},{"id":"T2300","span":{"begin":282,"end":295},"obj":"Transcription"},{"id":"T2299","span":{"begin":379,"end":396},"obj":"Protein"},{"id":"T2298","span":{"begin":234,"end":251},"obj":"Protein"},{"id":"T2297","span":{"begin":168,"end":173},"obj":"Protein"}],"relations":[{"id":"R1569","pred":"themeOf","subj":"T2298","obj":"T2300"},{"id":"R1571","pred":"themeOf","subj":"T2299","obj":"T2301"},{"id":"R1572","pred":"themeOf","subj":"T2300","obj":"T2302"}],"text":"Our previously published data indicated that SerpinB2 is distinctly regulated from other LPS-inducible genes in terms of kinetics, LPS dose response and sensitivity to IFN-γ co-stimulation [4]; however, the cis-acting elements in the SerpinB2 promoter responsible for LPS-dependent transcription in macrophages and the specific LPS-responsive transcription factors that bind the SerpinB2 promoter were not defined."}

{"project":"testone","denotations":[{"id":"T1127","span":{"begin":370,"end":374},"obj":"Binding"},{"id":"T1126","span":{"begin":68,"end":77},"obj":"Regulation"},{"id":"T1111","span":{"begin":379,"end":387},"obj":"Protein"},{"id":"T1110","span":{"begin":234,"end":242},"obj":"Protein"},{"id":"T1109","span":{"begin":168,"end":173},"obj":"Protein"},{"id":"T1108","span":{"begin":45,"end":53},"obj":"Protein"}],"relations":[{"id":"R748","pred":"themeOf","subj":"T1108","obj":"T1127"},{"id":"R749","pred":"themeOf","subj":"T1108","obj":"T1126"}],"text":"Our previously published data indicated that SerpinB2 is distinctly regulated from other LPS-inducible genes in terms of kinetics, LPS dose response and sensitivity to IFN-γ co-stimulation [4]; however, the cis-acting elements in the SerpinB2 promoter responsible for LPS-dependent transcription in macrophages and the specific LPS-responsive transcription factors that bind the SerpinB2 promoter were not defined."}

{"project":"test3","denotations":[{"id":"T1182","span":{"begin":379,"end":387},"obj":"Protein"},{"id":"T1181","span":{"begin":370,"end":374},"obj":"Binding"},{"id":"T1180","span":{"begin":234,"end":242},"obj":"Protein"},{"id":"T1179","span":{"begin":168,"end":173},"obj":"Protein"},{"id":"T1178","span":{"begin":68,"end":77},"obj":"Regulation"},{"id":"T1177","span":{"begin":45,"end":53},"obj":"Protein"},{"id":"T1152","span":{"begin":379,"end":387},"obj":"Protein"},{"id":"T1151","span":{"begin":234,"end":242},"obj":"Protein"},{"id":"T1150","span":{"begin":168,"end":173},"obj":"Protein"},{"id":"T1149","span":{"begin":45,"end":53},"obj":"Protein"}],"relations":[{"id":"R759","pred":"themeOf","subj":"T1177","obj":"T1178"},{"id":"R760","pred":"themeOf","subj":"T1182","obj":"T1181"}],"text":"Our previously published data indicated that SerpinB2 is distinctly regulated from other LPS-inducible genes in terms of kinetics, LPS dose response and sensitivity to IFN-γ co-stimulation [4]; however, the cis-acting elements in the SerpinB2 promoter responsible for LPS-dependent transcription in macrophages and the specific LPS-responsive transcription factors that bind the SerpinB2 promoter were not defined."}