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PMC:3586680 / 3751-5000 JSONTXT

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test3

Id Subject Object Predicate Lexical cue
T861 642-645 Protein denotes p53
T860 426-437 Protein denotes MicroRNA-21
T859 347-356 Protein denotes caspase-3
T858 331-336 Protein denotes Bcl-2
T857 327-330 Protein denotes Bax
T856 319-326 Negative_regulation denotes reduces
T855 307-318 Protein denotes microRNA-21
T854 233-243 Gene_expression denotes expression
T853 220-224 Protein denotes MGMT
T852 175-179 Protein denotes MGMT
T851 163-171 Positive_regulation denotes increase
T850 78-82 Protein denotes MGMT
T849 36-46 Binding denotes associated
T827 642-645 Protein denotes p53
T826 426-437 Protein denotes MicroRNA-21
T825 347-356 Protein denotes caspase-3
T824 331-336 Protein denotes Bcl-2
T823 327-330 Protein denotes Bax
T822 307-318 Protein denotes microRNA-21
T821 220-224 Protein denotes MGMT
T820 175-179 Protein denotes MGMT
T819 78-82 Protein denotes MGMT
R460 T853 T854 themeOf MGMT,expression

testone

Id Subject Object Predicate Lexical cue
T791 642-645 Protein denotes p53
T790 426-437 Protein denotes MicroRNA-21
T789 347-356 Protein denotes caspase-3
T788 331-336 Protein denotes Bcl-2
T787 327-330 Protein denotes Bax
T786 307-318 Protein denotes microRNA-21
T785 220-224 Protein denotes MGMT
T784 175-179 Protein denotes MGMT
T783 78-82 Protein denotes MGMT
T804 233-243 Gene_expression denotes expression
R449 T785 T804 themeOf MGMT,expression

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T2301 1145-1154 Regulation denotes regulated
T2300 1158-1178 Protein denotes cytochrome c oxidase
T2299 880-884 Protein denotes APNG
T2298 821-878 Protein denotes base excision repair enzyme alkylpurine-DNA-N-glycosylase
T2297 736-749 Protein denotes α5β1 integrin
T2296 642-645 Protein denotes p53
T2295 607-620 Protein denotes α5β1 integrin
T2294 319-326 Negative_regulation denotes reduces
T2293 319-326 Negative_regulation denotes reduces
T2292 319-326 Negative_regulation denotes reduces
T2291 347-356 Protein denotes caspase-3
T2290 331-336 Protein denotes Bcl-2
T2289 327-330 Protein denotes Bax
T2288 213-219 Negative_regulation denotes blocks
T2287 233-243 Gene_expression denotes expression
T2286 163-171 Positive_regulation denotes increase
T2285 220-232 Protein denotes MGMT protein
T2284 175-179 Protein denotes MGMT
T2283 78-96 Protein denotes MGMT gene promoter
R1533 T2284 T2286 themeOf MGMT,increase
R1534 T2285 T2287 themeOf MGMT protein,expression
R1537 T2287 T2288 themeOf expression,blocks
R1538 T2289 T2292 themeOf Bax,reduces
R1540 T2290 T2293 themeOf Bcl-2,reduces
R1541 T2291 T2294 themeOf caspase-3,reduces
R1544 T2300 T2301 themeOf cytochrome c oxidase,regulated

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T3228 1248-1249 . denotes .
T3227 1247-1248 -RRB- denotes )
T3226 1243-1247 CD denotes 2011
T3225 1241-1242 , denotes ,
T3224 1238-1241 FW denotes al.
T3223 1235-1237 FW denotes et
T3222 1229-1234 NNP denotes Oliva
T3221 1228-1229 -LRB- denotes (
T3220 1220-1227 NNS denotes gliomas
T3219 1217-1219 IN denotes in
T3218 1206-1216 NN denotes resistance
T3217 1202-1205 NNP denotes TMZ
T3216 1199-1201 TO denotes to
T3215 1194-1198 NN denotes part
T3214 1191-1193 IN denotes in
T3213 1179-1190 VBZ denotes contributes
T3212 1171-1178 NN denotes oxidase
T3211 1169-1170 NN denotes c
T3210 1158-1168 NN denotes cytochrome
T3209 1155-1157 IN denotes by
T3208 1145-1154 VBN denotes regulated
T3207 1143-1144 -RRB- denotes )
T3206 1140-1143 NNP denotes ROS
T3205 1139-1140 -LRB- denotes (
T3204 1131-1138 NNS denotes species
T3203 1124-1130 NN denotes oxygen
T3202 1115-1123 JJ denotes reactive
T3201 1112-1114 IN denotes of
T3200 1101-1111 NN denotes production
T3199 1097-1100 DT denotes the
T3198 1088-1096 VB denotes suppress
T3197 1085-1087 TO denotes to
T3196 1076-1084 NN denotes coupling
T3195 1070-1075 NN denotes chain
T3194 1058-1069 JJ denotes respiratory
T3193 1044-1057 JJ denotes mitochondrial
T3192 1041-1043 IN denotes of
T3191 1028-1040 NNP denotes Upregulation
T3190 1026-1027 . denotes .
T3189 1025-1026 -RRB- denotes )
T3188 1021-1025 CD denotes 2012
T3187 1019-1020 , denotes ,
T3186 1016-1019 FW denotes al.
T3185 1013-1015 FW denotes et
T3184 1003-1012 NNP denotes Agnihotri
T3183 1002-1003 -LRB- denotes (
T3182 991-1001 NN denotes resistance
T3181 987-990 NNP denotes TMZ
T3180 983-986 DT denotes the
T3179 980-982 IN denotes in
T3178 967-979 VBZ denotes participates
T3177 962-966 RB denotes also
T3176 960-961 , denotes ,
T3175 944-960 JJ denotes N7-methylguanine
T3174 940-943 CC denotes and
T3173 923-939 JJ denotes N3-methyladenine
T3172 915-922 NNS denotes lesions
T3171 905-914 JJ denotes cytotoxic
T3170 901-904 DT denotes the
T3169 893-900 NNS denotes repairs
T3168 887-892 WDT denotes which
T3167 885-886 , denotes ,
T3166 884-885 -RRB- denotes )
T3165 880-884 NNP denotes APNG
T3164 879-880 -LRB- denotes (
T3163 849-878 JJ denotes alkylpurine-DNA-N-glycosylase
T3162 842-848 NN denotes enzyme
T3161 835-841 NN denotes repair
T3160 826-834 NN denotes excision
T3159 821-825 NN denotes base
T3158 817-820 DT denotes The
T3157 815-816 . denotes .
T3156 809-815 NNS denotes tumors
T3155 803-808 NN denotes brain
T3154 792-802 JJ denotes high-grade
T3153 788-791 IN denotes for
T3152 781-787 NN denotes target
T3151 769-780 JJ denotes therapeutic
T3150 767-768 DT denotes a
T3149 764-766 IN denotes as
T3148 753-763 VBN denotes considered
T3147 750-752 VBZ denotes is
T3146 741-749 NN denotes integrin
T3145 736-740 JJ denotes α5β1
T3144 734-735 . denotes .
T3143 733-734 -RRB- denotes )
T3142 729-733 CD denotes 2012
T3141 727-728 , denotes ,
T3140 724-727 FW denotes al.
T3139 721-723 FW denotes et
T3138 710-720 NNP denotes Janouskova
T3137 709-710 -LRB- denotes (
T3136 705-708 NNP denotes TMZ
T3135 702-704 TO denotes to
T3134 691-701 NN denotes resistance
T3133 686-690 NN denotes cell
T3132 679-685 NN denotes glioma
T3131 671-678 VBZ denotes induces
T3130 665-670 NN denotes event
T3129 661-664 DT denotes the
T3128 657-660 CC denotes and
T3127 655-656 , denotes ,
T3126 646-655 VBG denotes signaling
T3125 642-645 NN denotes p53
T3124 632-641 VBZ denotes regulates
T3123 621-631 RB denotes negatively
T3122 612-620 NN denotes integrin
T3121 607-611 JJ denotes α5β1
T3120 605-606 . denotes .
T3119 593-605 JJ denotes chemotherapy
T3118 589-592 CC denotes and
T3117 576-588 JJ denotes radiotherapy
T3111 538-541 DT denotes the
T3110 535-537 IN denotes in
T3109 530-534 NN denotes role
T3108 528-529 DT denotes a
T3107 523-527 VBP denotes play
T3106 513-522 NNS denotes Integrins
T3105 511-512 . denotes .
T3104 510-511 -RRB- denotes )
T3103 506-510 CD denotes 2012
T3102 504-505 , denotes ,
T3101 501-504 FW denotes al.
T3100 498-500 FW denotes et
T3099 495-497 NNP denotes Li
T3098 494-495 -LRB- denotes (
T3097 488-493 NNS denotes cells
T3096 481-487 NN denotes cancer
T3095 477-480 IN denotes for
T3094 470-476 NN denotes factor
T3093 457-469 JJ denotes pro-survival
T3092 455-456 DT denotes a
T3091 452-454 IN denotes as
T3090 441-451 VBN denotes considered
T3089 438-440 VBZ denotes is
T3088 426-437 NN denotes MicroRNA-21
T3087 424-425 . denotes .
T3086 423-424 -RRB- denotes )
T3085 419-423 CD denotes 2010
T3084 417-418 , denotes ,
T3083 414-417 FW denotes al.
T3082 411-413 FW denotes et
T3081 407-410 NNP denotes Shi
T3080 406-407 -LRB- denotes (
T3079 396-405 NN denotes apoptosis
T3078 384-395 JJ denotes TMZ-induced
T3077 375-383 VBG denotes blocking
T3076 367-374 RB denotes thereby
T3075 365-366 , denotes ,
T3074 357-365 NN denotes activity
T3073 347-356 JJ denotes caspase-3
T3072 343-346 CC denotes and
T3071 337-342 NN denotes ratio
T3070 334-336 CD denotes -2
T3069 327-334 NNP denotes Bax/Bcl
T3068 319-326 VBZ denotes reduces
T3067 307-318 NN denotes microRNA-21
T3066 293-306 VBD denotes overexpressed
T3065 291-292 , denotes ,
T3064 279-291 RB denotes Intriguingly
T3063 277-278 . denotes .
T3062 269-277 NN denotes survival
T3061 261-268 NN denotes patient
T3060 254-260 NN denotes cancer
T3059 245-253 VBZ denotes prolongs
T3058 243-244 , denotes ,
T3057 233-243 NN denotes expression
T3056 225-232 NN denotes protein
T3055 220-224 NNP denotes MGMT
T3054 213-219 VBZ denotes blocks
T3053 207-212 WDT denotes which
T3052 205-206 , denotes ,
T3051 194-205 NN denotes methylation
T3050 185-193 NN denotes promoter
T3049 180-184 NN denotes gene
T3048 175-179 NNP denotes MGMT
T3047 172-174 IN denotes in
T3046 163-171 NN denotes increase
T3045 160-162 DT denotes An
T3044 158-159 . denotes .
T3043 157-158 -RRB- denotes )
T3042 153-157 CD denotes 2012
T3041 151-152 , denotes ,
T3040 148-151 FW denotes al.
T3039 145-147 FW denotes et
T3038 136-144 NNP denotes Villalva
T3037 135-136 -LRB- denotes (
T3036 119-134 NN denotes differentiation
T3035 116-118 TO denotes to
T3034 106-115 VBN denotes committed
T3033 100-105 NNS denotes cells
T3032 97-99 IN denotes in
T3031 88-96 NN denotes promoter
T3030 83-87 NN denotes gene
T3029 78-82 NNP denotes MGMT
T3028 75-77 IN denotes of
T3027 68-74 NN denotes status
T3026 56-67 NN denotes methylation
T3025 52-55 DT denotes the
T3024 47-51 IN denotes with
T3023 36-46 VBN denotes associated
T3022 22-35 RB denotes significantly
T3021 19-21 VBZ denotes is
T3020 15-18 NNP denotes TMZ
T3019 12-14 TO denotes to
T3018 0-11 NN denotes Sensitivity
T3116 573-575 TO denotes to
T3115 565-572 NNS denotes cancers
T3114 556-564 JJ denotes advanced
T3113 553-555 IN denotes of
T3112 542-552 NN denotes resistance
R2079 T3055 T3057 compound MGMT,expression
R2085 T3056 T3057 compound protein,expression
R2089 T3057 T3054 dobj expression,blocks
R2093 T3058 T3059 punct ",",prolongs
R2095 T3018 T3023 nsubjpass Sensitivity,associated
R2096 T3019 T3018 prep to,Sensitivity
R2097 T3059 T3059 ROOT prolongs,prolongs
R2098 T3020 T3019 pobj TMZ,to
R2099 T3060 T3062 compound cancer,survival
R2100 T3061 T3062 compound patient,survival
R2101 T3021 T3023 auxpass is,associated
R2102 T3022 T3023 advmod significantly,associated
R2103 T3062 T3059 dobj survival,prolongs
R2104 T3023 T3023 ROOT associated,associated
R2105 T3024 T3023 prep with,associated
R2106 T3025 T3027 det the,status
R2107 T3026 T3027 amod methylation,status
R2108 T3027 T3024 pobj status,with
R2109 T3028 T3027 prep of,status
R2110 T3063 T3059 punct .,prolongs
R2111 T3029 T3031 compound MGMT,promoter
R2112 T3030 T3031 compound gene,promoter
R2113 T3031 T3028 pobj promoter,of
R2114 T3064 T3068 advmod Intriguingly,reduces
R2115 T3032 T3027 prep in,status
R2116 T3033 T3032 pobj cells,in
R2117 T3065 T3068 punct ",",reduces
R2118 T3034 T3033 acl committed,cells
R2119 T3035 T3034 prep to,committed
R2120 T3036 T3035 pobj differentiation,to
R2121 T3066 T3067 amod overexpressed,microRNA-21
R2122 T3037 T3040 punct (,al.
R2123 T3038 T3040 compound Villalva,al.
R2124 T3039 T3040 nmod et,al.
R2125 T3067 T3068 nsubj microRNA-21,reduces
R2126 T3040 T3027 appos al.,status
R2127 T3041 T3040 punct ",",al.
R2128 T3042 T3040 npadvmod 2012,al.
R2129 T3068 T3068 ROOT reduces,reduces
R2130 T3043 T3023 punct ),associated
R2131 T3044 T3023 punct .,associated
R2132 T3045 T3046 det An,increase
R2133 T3069 T3071 nmod Bax/Bcl,ratio
R2134 T3046 T3059 nsubj increase,prolongs
R2135 T3047 T3046 prep in,increase
R2136 T3048 T3051 compound MGMT,methylation
R2137 T3070 T3069 nummod -2,Bax/Bcl
R2138 T3049 T3050 compound gene,promoter
R2139 T3050 T3051 compound promoter,methylation
R2140 T3051 T3047 pobj methylation,in
R2141 T3071 T3068 dobj ratio,reduces
R2142 T3052 T3051 punct ",",methylation
R2143 T3053 T3054 nsubj which,blocks
R2144 T3054 T3051 relcl blocks,methylation
R2145 T3072 T3071 cc and,ratio
R2146 T3073 T3074 amod caspase-3,activity
R2147 T3074 T3071 conj activity,ratio
R2148 T3152 T3149 pobj target,as
R2149 T3153 T3152 prep for,target
R2150 T3075 T3068 punct ",",reduces
R2151 T3154 T3156 amod high-grade,tumors
R2152 T3155 T3156 compound brain,tumors
R2153 T3076 T3077 advmod thereby,blocking
R2154 T3156 T3153 pobj tumors,for
R2155 T3157 T3148 punct .,considered
R2156 T3158 T3162 det The,enzyme
R2157 T3159 T3162 amod base,enzyme
R2158 T3160 T3162 compound excision,enzyme
R2159 T3161 T3162 compound repair,enzyme
R2160 T3162 T3178 nsubj enzyme,participates
R2161 T3077 T3068 advcl blocking,reduces
R2162 T3163 T3162 amod alkylpurine-DNA-N-glycosylase,enzyme
R2163 T3164 T3165 punct (,APNG
R2164 T3165 T3163 appos APNG,alkylpurine-DNA-N-glycosylase
R2165 T3078 T3079 amod TMZ-induced,apoptosis
R2166 T3166 T3165 punct ),APNG
R2167 T3167 T3163 punct ",",alkylpurine-DNA-N-glycosylase
R2168 T3079 T3077 dobj apoptosis,blocking
R2169 T3168 T3169 nsubj which,repairs
R2170 T3080 T3083 punct (,al.
R2171 T3169 T3163 relcl repairs,alkylpurine-DNA-N-glycosylase
R2172 T3170 T3172 det the,lesions
R2173 T3081 T3083 compound Shi,al.
R2174 T3171 T3172 amod cytotoxic,lesions
R2175 T3172 T3169 dobj lesions,repairs
R2176 T3173 T3169 advmod N3-methyladenine,repairs
R2177 T3082 T3083 nmod et,al.
R2178 T3174 T3173 cc and,N3-methyladenine
R2179 T3083 T3083 ROOT al.,al.
R2180 T3175 T3173 conj N7-methylguanine,N3-methyladenine
R2181 T3176 T3178 punct ",",participates
R2182 T3084 T3083 punct ",",al.
R2183 T3177 T3178 advmod also,participates
R2184 T3178 T3178 ROOT participates,participates
R2185 T3179 T3178 prep in,participates
R2186 T3085 T3083 npadvmod 2010,al.
R2187 T3180 T3182 det the,resistance
R2188 T3181 T3182 compound TMZ,resistance
R2189 T3182 T3179 pobj resistance,in
R2190 T3086 T3083 punct ),al.
R2191 T3183 T3186 punct (,al.
R2192 T3184 T3186 nmod Agnihotri,al.
R2193 T3185 T3186 nmod et,al.
R2194 T3087 T3083 punct .,al.
R2195 T3186 T3178 dep al.,participates
R2196 T3187 T3186 punct ",",al.
R2197 T3188 T3186 npadvmod 2012,al.
R2198 T3088 T3090 nsubjpass MicroRNA-21,considered
R2199 T3189 T3186 punct ),al.
R2200 T3190 T3178 punct .,participates
R2201 T3191 T3191 ROOT Upregulation,Upregulation
R2202 T3089 T3090 auxpass is,considered
R2203 T3192 T3191 prep of,Upregulation
R2204 T3193 T3196 amod mitochondrial,coupling
R2205 T3090 T3090 ROOT considered,considered
R2206 T3194 T3195 amod respiratory,chain
R2207 T3195 T3196 compound chain,coupling
R2208 T3196 T3192 pobj coupling,of
R2209 T3091 T3090 prep as,considered
R2210 T3092 T3094 det a,factor
R2211 T3197 T3198 aux to,suppress
R2212 T3198 T3191 advcl suppress,Upregulation
R2213 T3093 T3094 amod pro-survival,factor
R2214 T3199 T3200 det the,production
R2215 T3200 T3198 dobj production,suppress
R2216 T3094 T3091 pobj factor,as
R2217 T3201 T3200 prep of,production
R2218 T3202 T3204 amod reactive,species
R2219 T3203 T3204 compound oxygen,species
R2220 T3095 T3094 prep for,factor
R2221 T3204 T3201 pobj species,of
R2222 T3205 T3208 punct (,regulated
R2223 T3206 T3208 dep ROS,regulated
R2224 T3096 T3097 compound cancer,cells
R2225 T3207 T3208 punct ),regulated
R2226 T3097 T3095 pobj cells,for
R2227 T3208 T3198 advcl regulated,suppress
R2228 T3098 T3101 punct (,al.
R2229 T3209 T3208 agent by,regulated
R2230 T3210 T3212 compound cytochrome,oxidase
R2231 T3211 T3212 compound c,oxidase
R2232 T3099 T3101 compound Li,al.
R2233 T3212 T3209 pobj oxidase,by
R2234 T3213 T3208 punct contributes,regulated
R2235 T3100 T3101 nmod et,al.
R2236 T3214 T3213 prep in,contributes
R2237 T3215 T3214 pobj part,in
R2238 T3216 T3215 prep to,part
R2239 T3101 T3094 appos al.,factor
R2240 T3217 T3218 compound TMZ,resistance
R2241 T3218 T3216 pobj resistance,to
R2242 T3219 T3218 prep in,resistance
R2243 T3102 T3101 punct ",",al.
R2244 T3220 T3219 pobj gliomas,in
R2245 T3221 T3224 punct (,al.
R2246 T3222 T3224 compound Oliva,al.
R2247 T3103 T3101 npadvmod 2012,al.
R2248 T3223 T3224 nmod et,al.
R2249 T3224 T3208 dep al.,regulated
R2250 T3104 T3101 punct ),al.
R2251 T3225 T3224 punct ",",al.
R2252 T3226 T3224 npadvmod 2011,al.
R2253 T3227 T3224 punct ),al.
R2254 T3105 T3090 punct .,considered
R2255 T3228 T3191 punct .,Upregulation
R2261 T3106 T3107 nsubj Integrins,play
R2265 T3107 T3107 ROOT play,play
R2269 T3108 T3109 det a,role
R2272 T3109 T3107 dobj role,play
R2277 T3110 T3109 prep in,role
R2279 T3111 T3112 det the,resistance
R2281 T3112 T3110 pobj resistance,in
R2282 T3113 T3112 prep of,resistance
R2284 T3114 T3115 amod advanced,cancers
R2285 T3115 T3113 pobj cancers,of
R2288 T3116 T3117 aux to,radiotherapy
R2292 T3117 T3115 relcl radiotherapy,cancers
R2295 T3118 T3117 cc and,radiotherapy
R2296 T3119 T3117 conj chemotherapy,radiotherapy
R2298 T3120 T3107 punct .,play
R2302 T3121 T3122 amod α5β1,integrin
R2306 T3122 T3124 nsubj integrin,regulates
R2313 T3123 T3124 advmod negatively,regulates
R2317 T3124 T3124 ROOT regulates,regulates
R2322 T3125 T3124 dobj p53,regulates
R2325 T3126 T3125 acl signaling,p53
R2329 T3127 T3124 punct ",",regulates
R2333 T3128 T3124 cc and,regulates
R2337 T3129 T3130 det the,event
R2339 T3130 T3131 nsubj event,induces
R2341 T3131 T3124 conj induces,regulates
R2342 T3132 T3134 amod glioma,resistance
R2346 T3133 T3134 compound cell,resistance
R2349 T3134 T3131 dobj resistance,induces
R2353 T3135 T3134 prep to,resistance
R2358 T3136 T3135 pobj TMZ,to
R2365 T3137 T3140 punct (,al.
R2369 T3138 T3140 nmod Janouskova,al.
R2373 T3139 T3140 nmod et,al.
R2376 T3140 T3134 appos al.,resistance
R2377 T3141 T3140 punct ",",al.
R2379 T3142 T3140 npadvmod 2012,al.
R2384 T3143 T3131 punct ),induces
R2388 T3144 T3124 punct .,regulates
R2392 T3145 T3146 amod α5β1,integrin
R2396 T3146 T3148 nsubjpass integrin,considered
R2400 T3147 T3148 auxpass is,considered
R2405 T3148 T3148 ROOT considered,considered
R2408 T3149 T3148 prep as,considered
R2414 T3150 T3152 det a,target
R2418 T3151 T3152 amod therapeutic,target

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T2502 207-244 Negative_regulation denotes which blocks MGMT protein expression,
T2501 160-206 Positive_regulation denotes An increase in MGMT gene promoter methylation,
T2499 642-655 Positive_regulation denotes p53 signaling
T2497 1041-1084 Binding denotes of mitochondrial respiratory chain coupling
T2496 220-244 Gene_expression denotes MGMT protein expression,
T2495 1085-1138 Negative_regulation denotes to suppress the production of reactive oxygen species
T2494 293-318 Positive_regulation denotes overexpressed microRNA-21
T2493 293-318 Gene_expression denotes overexpressed microRNA-21
T2492 1028-1138 Positive_regulation denotes Upregulation of mitochondrial respiratory chain coupling to suppress the production of reactive oxygen species
T2490 1044-1075 Entity denotes mitochondrial respiratory chain
T2486 513-522 Entity denotes Integrins
T2482 220-224 Protein denotes MGMT
T2477 100-105 Entity denotes cells
T2467 1202-1205 Entity denotes TMZ
T2462 944-961 Entity denotes N7-methylguanine,
T2460 1155-1193 Protein denotes by cytochrome c oxidase contributes in
T2458 78-82 Protein denotes MGMT
T2449 426-437 Protein denotes MicroRNA-21
T2448 327-336 Protein denotes Bax/Bcl-2
T2443 172-206 Protein denotes in MGMT gene promoter methylation,
T2437 175-179 Protein denotes MGMT
T2435 327-336 Protein denotes Bax/Bcl-2
T2432 901-939 Entity denotes the cytotoxic lesions N3-methyladenine
T2421 15-18 Entity denotes TMZ
T2414 987-990 Entity denotes TMZ
T2410 481-493 Entity denotes cancer cells
T2409 185-193 Entity denotes promoter
T2407 293-318 Protein denotes overexpressed microRNA-21
T2406 75-96 Entity denotes of MGMT gene promoter
T2403 407-410 Protein denotes Shi
T2397 384-395 Entity denotes TMZ-induced
T2395 75-96 Protein denotes of MGMT gene promoter
T2390 679-690 Entity denotes glioma cell
T2388 220-232 Protein denotes MGMT protein
T2386 642-645 Protein denotes p53
T2375 331-336 Protein denotes Bcl-2
T2372 705-734 Entity denotes TMZ (Janouskova et al., 2012)
T2371 905-914 Entity denotes cytotoxic
T2370 347-356 Protein denotes caspase-3
T2368 817-848 Protein denotes The base excision repair enzyme
T2365 1171-1178 Protein denotes oxidase
T2363 944-961 Entity denotes N7-methylguanine,
T2362 1140-1143 Protein denotes ROS
R1562 T2386 T2499 causeOf p53,p53 signaling
R1563 T2388 T2496 themeOf MGMT protein,"MGMT protein expression,"
R1568 T2406 T2458 partOf of MGMT gene promoter,MGMT
R1569 T2407 T2493 themeOf overexpressed microRNA-21,overexpressed microRNA-21
R1570 T2407 T2494 themeOf overexpressed microRNA-21,overexpressed microRNA-21
R1573 T2490 T2497 themeOf mitochondrial respiratory chain,of mitochondrial respiratory chain coupling
R1574 T2496 T2502 themeOf "MGMT protein expression,","which blocks MGMT protein expression,"
R1575 T2497 T2492 themeOf of mitochondrial respiratory chain coupling,Upregulation of mitochondrial respiratory chain coupling to suppress the production of reactive oxygen species

DLUT931

Id Subject Object Predicate Lexical cue
T2195 632-641 Regulation denotes regulates
T2194 293-306 Positive_regulation denotes overexpressed
T2193 213-219 Negative_regulation denotes blocks
T2192 233-243 Gene_expression denotes expression
T2191 163-171 Positive_regulation denotes increase
T2175 642-645 Protein denotes p53
T2174 426-437 Protein denotes MicroRNA-21
T2173 347-356 Protein denotes caspase-3
T2172 331-336 Protein denotes Bcl-2
T2171 327-330 Protein denotes Bax
T2170 307-318 Protein denotes microRNA-21
T2169 220-224 Protein denotes MGMT
T2168 175-179 Protein denotes MGMT
T2167 78-82 Protein denotes MGMT
R1495 T2168 T2191 themeOf MGMT,increase
R1496 T2169 T2192 themeOf MGMT,expression
R1497 T2170 T2194 themeOf microRNA-21,overexpressed
R1498 T2175 T2195 themeOf p53,regulates
R1507 T2192 T2193 themeOf expression,blocks

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T2251 642-645 Protein denotes p53
T2250 426-437 Protein denotes MicroRNA-21
T2249 347-356 Protein denotes caspase-3
T2248 331-336 Protein denotes Bcl-2
T2247 327-330 Protein denotes Bax
T2246 307-318 Protein denotes microRNA-21
T2245 220-224 Protein denotes MGMT
T2244 175-179 Protein denotes MGMT
T2243 78-82 Protein denotes MGMT
T2266 319-326 Negative_regulation denotes reduces
T2265 293-306 Positive_regulation denotes overexpressed
T2264 213-219 Negative_regulation denotes blocks
T2263 233-243 Gene_expression denotes expression
R1524 T2245 T2263 themeOf MGMT,expression
R1525 T2246 T2265 themeOf microRNA-21,overexpressed
R1527 T2249 T2266 themeOf caspase-3,reduces
R1543 T2263 T2264 themeOf expression,blocks

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T2133 293-306 Positive_regulation denotes overexpressed
T2132 293-306 Gene_expression denotes overexpressed
T2131 319-326 Negative_regulation denotes reduces
T2130 213-219 Negative_regulation denotes blocks
T2129 233-243 Gene_expression denotes expression
T2117 642-645 Protein denotes p53
T2116 426-437 Protein denotes MicroRNA-21
T2115 347-356 Protein denotes caspase-3
T2114 331-336 Protein denotes Bcl-2
T2113 327-330 Protein denotes Bax
T2112 307-318 Protein denotes microRNA-21
T2111 220-224 Protein denotes MGMT
T2110 175-179 Protein denotes MGMT
T2109 78-82 Protein denotes MGMT
R1478 T2111 T2129 themeOf MGMT,expression
R1479 T2112 T2132 themeOf microRNA-21,overexpressed
R1480 T2112 T2131 causeOf microRNA-21,reduces
R1481 T2115 T2131 themeOf caspase-3,reduces
R1490 T2129 T2130 themeOf expression,blocks
R1492 T2132 T2133 themeOf overexpressed,overexpressed

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T2157 642-645 http://www.uniprot.org/uniprot/P04637 denotes p53
T2156 347-356 http://www.uniprot.org/uniprot/P42574 denotes caspase-3
T2153 220-224 http://www.uniprot.org/uniprot/P16455 denotes MGMT
T2152 175-179 http://www.uniprot.org/uniprot/P16455 denotes MGMT
T2151 78-82 http://www.uniprot.org/uniprot/P16455 denotes MGMT

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T1958 642-645 Protein denotes p53
T1957 426-437 Protein denotes MicroRNA-21
T1956 347-356 Protein denotes caspase-3
T1955 331-336 Protein denotes Bcl-2
T1954 327-330 Protein denotes Bax
T1953 307-318 Protein denotes microRNA-21
T1952 220-224 Protein denotes MGMT
T1951 175-179 Protein denotes MGMT
T1950 78-82 Protein denotes MGMT

bionlp-st-ge-2016-coref

Id Subject Object Predicate Lexical cue
T1940 194-205 Antecedent denotes methylation
T1939 207-212 Anaphor denotes which
R1455 T1939 T1940 boundBy which,methylation

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T1554 923-939 NN denotes N3-methyladenine
T1553 915-922 NN denotes lesions
T1552 905-914 JJ denotes cytotoxic
T1551 901-904 DT denotes the
T1550 893-900 VB denotes repairs
T1549 887-892 WDT denotes which
T1548 885-886 -COMMA- denotes ,
T1547 884-885 -RRB- denotes )
T1546 880-884 NN denotes APNG
T1545 879-880 -LRB- denotes (
T1544 849-878 NN denotes alkylpurine-DNA-N-glycosylase
T1543 842-848 NN denotes enzyme
T1542 835-841 NN denotes repair
T1541 826-834 NN denotes excision
T1540 821-825 NN denotes base
T1539 817-820 DT denotes The
T1538 797-803 NN denotes grade
T1537 792-797 NN denotes high-
T1536 781-791 JJ denotes target for
T1535 778-781 IN denotes ic
T1534 772-778 NN denotes rapeut
T1533 761-772 JJ denotes ed as a the
T1532 760-761 DT denotes r
T1531 758-760 IN denotes de
T1530 748-758 VB denotes n is consi
T1529 746-748 VB denotes ri
T1528 738-746 NN denotes β1 integ
T1527 734-738 CD denotes . α5
T1526 733-734 -RRB- denotes )
T1525 729-733 CD denotes 2012
T1524 727-728 -COMMA- denotes ,
T1523 724-727 FW denotes al.
T1522 721-723 FW denotes et
T1521 710-720 NNP denotes Janouskova
T1520 709-710 -LRB- denotes (
T1519 705-708 NN denotes TMZ
T1518 702-704 TO denotes to
T1517 691-701 NN denotes resistance
T1516 686-690 NN denotes cell
T1515 679-685 NN denotes glioma
T1514 671-678 VB denotes induces
T1513 665-670 NN denotes event
T1512 661-664 DT denotes the
T1511 657-660 CC denotes and
T1510 655-656 -COMMA- denotes ,
T1509 646-655 NN denotes signaling
T1508 642-645 NN denotes p53
T1507 632-641 VB denotes regulates
T1506 621-631 RB denotes negatively
T1505 612-620 NN denotes integrin
T1504 607-611 NN denotes α5β1
T1503 593-606 NN denotes chemotherapy.
T1502 589-592 CC denotes and
T1501 576-588 NN denotes radiotherapy
T1500 573-575 TO denotes to
T1499 565-572 NN denotes cancers
T1498 556-564 JJ denotes advanced
T1497 553-555 IN denotes of
T1496 542-552 NN denotes resistance
T1495 538-541 DT denotes the
T1494 535-537 IN denotes in
T1493 530-534 NN denotes role
T1492 528-529 DT denotes a
T1491 523-527 VB denotes play
T1490 513-522 NN denotes Integrins
T1489 510-511 -RRB- denotes )
T1488 506-510 CD denotes 2012
T1487 504-505 -COMMA- denotes ,
T1486 501-504 FW denotes al.
T1485 498-500 FW denotes et
T1484 495-497 NNP denotes Li
T1483 494-495 -LRB- denotes (
T1482 488-493 NN denotes cells
T1481 481-487 NN denotes cancer
T1480 477-480 IN denotes for
T1479 470-476 NN denotes factor
T1478 457-469 JJ denotes pro-survival
T1477 455-456 DT denotes a
T1476 452-454 IN denotes as
T1475 441-451 VB denotes considered
T1474 438-440 VB denotes is
T1473 426-437 NN denotes MicroRNA-21
T1472 423-424 -RRB- denotes )
T1471 419-423 CD denotes 2010
T1470 417-418 -COMMA- denotes ,
T1469 414-417 FW denotes al.
T1468 411-413 FW denotes et
T1467 407-410 NNP denotes Shi
T1466 406-407 -LRB- denotes (
T1465 396-405 NN denotes apoptosis
T1464 384-395 JJ denotes TMZ-induced
T1463 375-383 VB denotes blocking
T1462 367-374 RB denotes thereby
T1461 365-366 -COMMA- denotes ,
T1460 357-365 NN denotes activity
T1459 347-356 NN denotes caspase-3
T1458 343-346 CC denotes and
T1457 337-342 NN denotes ratio
T1456 327-336 NN denotes Bax/Bcl-2
T1455 319-326 VB denotes reduces
T1454 307-318 NN denotes microRNA-21
T1453 293-306 VB denotes overexpressed
T1452 291-292 -COMMA- denotes ,
T1451 279-291 RB denotes Intriguingly
T1450 269-277 NN denotes survival
T1449 261-268 NN denotes patient
T1448 254-260 NN denotes cancer
T1447 245-253 VB denotes prolongs
T1446 243-244 -COMMA- denotes ,
T1445 233-243 NN denotes expression
T1444 225-232 NN denotes protein
T1443 220-224 NN denotes MGMT
T1442 213-219 VB denotes blocks
T1441 207-212 WDT denotes which
T1440 205-206 -COMMA- denotes ,
T1439 194-205 NN denotes methylation
T1438 185-193 NN denotes promoter
T1437 180-184 NN denotes gene
T1436 175-179 NN denotes MGMT
T1435 172-174 IN denotes in
T1434 163-171 NN denotes increase
T1433 160-162 DT denotes An
T1432 157-158 -RRB- denotes )
T1431 153-157 CD denotes 2012
T1430 151-152 -COMMA- denotes ,
T1429 148-151 FW denotes al.
T1428 145-147 FW denotes et
T1427 136-144 FW denotes Villalva
T1426 135-136 -LRB- denotes (
T1425 119-134 NN denotes differentiation
T1424 116-118 TO denotes to
T1423 106-115 VB denotes committed
T1422 100-105 NN denotes cells
T1421 97-99 IN denotes in
T1420 88-96 NN denotes promoter
T1419 83-87 NN denotes gene
T1418 78-82 NN denotes MGMT
T1417 75-77 IN denotes of
T1416 68-74 NN denotes status
T1415 56-67 NN denotes methylation
T1414 52-55 DT denotes the
T1413 47-51 IN denotes with
T1412 36-46 VB denotes associated
T1411 22-35 RB denotes significantly
T1410 19-21 VB denotes is
T1409 15-18 NN denotes TMZ
T1408 12-14 TO denotes to
T1407 0-11 NN denotes Sensitivity
T1607 1247-1248 -RRB- denotes )
T1606 1243-1247 CD denotes 2011
T1605 1241-1242 -COMMA- denotes ,
T1604 1238-1241 FW denotes al.
T1603 1235-1237 FW denotes et
T1602 1229-1234 NNP denotes Oliva
T1601 1228-1229 -LRB- denotes (
T1600 1220-1227 NN denotes gliomas
T1599 1217-1219 IN denotes in
T1598 1206-1216 NN denotes resistance
T1597 1202-1205 NN denotes TMZ
T1596 1199-1201 TO denotes to
T1595 1194-1198 NN denotes part
T1594 1191-1193 IN denotes in
T1593 1179-1190 VB denotes contributes
T1592 1171-1178 NN denotes oxidase
T1591 1169-1170 NN denotes c
T1590 1158-1168 NN denotes cytochrome
T1589 1155-1157 IN denotes by
T1588 1145-1154 VB denotes regulated
T1587 1143-1144 -RRB- denotes )
T1586 1140-1143 NN denotes ROS
T1585 1139-1140 -LRB- denotes (
T1584 1131-1138 NN denotes species
T1583 1124-1130 NN denotes oxygen
T1582 1115-1123 JJ denotes reactive
T1581 1112-1114 IN denotes of
T1580 1101-1111 NN denotes production
T1579 1097-1100 DT denotes the
T1578 1088-1096 VB denotes suppress
T1577 1085-1087 TO denotes to
T1576 1076-1084 NN denotes coupling
T1575 1070-1075 NN denotes chain
T1574 1058-1069 JJ denotes respiratory
T1573 1044-1057 JJ denotes mitochondrial
T1572 1041-1043 IN denotes of
T1571 1028-1040 NN denotes Upregulation
T1570 1025-1026 -RRB- denotes )
T1569 1021-1025 CD denotes 2012
T1568 1019-1020 -COMMA- denotes ,
T1567 1016-1019 FW denotes al.
T1566 1013-1015 FW denotes et
T1565 1003-1012 NNP denotes Agnihotri
T1564 1002-1003 -LRB- denotes (
T1563 991-1001 NN denotes resistance
T1562 987-990 NN denotes TMZ
T1561 983-986 DT denotes the
T1560 980-982 IN denotes in
T1559 967-979 VB denotes participates
T1558 962-966 RB denotes also
T1557 960-961 -COMMA- denotes ,
T1556 944-960 NN denotes N7-methylguanine
T1555 940-943 CC denotes and
R958 T1407 T1408 arg1Of Sensitivity,to
R959 T1407 T1410 arg1Of Sensitivity,is
R960 T1407 T1412 arg2Of Sensitivity,associated
R961 T1409 T1408 arg2Of TMZ,to
R962 T1412 T1410 arg2Of associated,is
R963 T1412 T1411 arg1Of associated,significantly
R964 T1412 T1413 arg1Of associated,with
R965 T1416 T1413 arg2Of status,with
R966 T1416 T1414 arg1Of status,the
R967 T1416 T1415 arg1Of status,methylation
R968 T1416 T1417 arg1Of status,of
R969 T1420 T1417 arg2Of promoter,of
R970 T1420 T1418 arg1Of promoter,MGMT
R971 T1420 T1419 arg1Of promoter,gene
R972 T1420 T1421 arg1Of promoter,in
R973 T1422 T1421 arg2Of cells,in
R974 T1422 T1423 arg2Of cells,committed
R975 T1423 T1424 arg1Of committed,to
R976 T1425 T1424 arg2Of differentiation,to
R977 T1425 T1426 arg1Of differentiation,(
R978 T1429 T1426 arg2Of al.,(
R979 T1429 T1427 arg1Of al.,Villalva
R980 T1429 T1428 arg1Of al.,et
R981 T1429 T1430 arg1Of al.,","
R982 T1431 T1430 arg2Of 2012,","
R983 T1432 T1426 arg3Of ),(
R984 T1434 T1433 arg1Of increase,An
R985 T1434 T1435 arg1Of increase,in
R986 T1434 T1440 arg1Of increase,","
R987 T1434 T1441 arg1Of increase,which
R988 T1434 T1442 arg1Of increase,blocks
R989 T1434 T1447 arg1Of increase,prolongs
R990 T1439 T1435 arg2Of methylation,in
R991 T1439 T1436 arg1Of methylation,MGMT
R992 T1439 T1437 arg1Of methylation,gene
R993 T1439 T1438 arg1Of methylation,promoter
R994 T1445 T1442 arg2Of expression,blocks
R995 T1445 T1443 arg1Of expression,MGMT
R996 T1445 T1444 arg1Of expression,protein
R997 T1447 T1446 arg1Of prolongs,","
R998 T1450 T1447 arg2Of survival,prolongs
R999 T1450 T1448 arg1Of survival,cancer
R1000 T1450 T1449 arg1Of survival,patient
R1001 T1454 T1453 arg2Of microRNA-21,overexpressed
R1002 T1454 T1455 arg1Of microRNA-21,reduces
R1003 T1455 T1451 arg1Of reduces,Intriguingly
R1004 T1455 T1452 arg1Of reduces,","
R1005 T1455 T1461 arg1Of reduces,","
R1006 T1455 T1463 modOf reduces,blocking
R1007 T1457 T1456 arg1Of ratio,Bax/Bcl-2
R1008 T1457 T1458 arg1Of ratio,and
R1009 T1458 T1455 arg2Of and,reduces
R1010 T1460 T1458 arg2Of activity,and
R1011 T1460 T1459 arg1Of activity,caspase-3
R1012 T1463 T1462 arg1Of blocking,thereby
R1013 T1465 T1463 arg2Of apoptosis,blocking
R1014 T1465 T1464 arg1Of apoptosis,TMZ-induced
R1015 T1465 T1466 arg1Of apoptosis,(
R1016 T1467 T1466 arg2Of Shi,(
R1017 T1467 T1468 arg1Of Shi,et
R1018 T1467 T1469 arg1Of Shi,al.
R1019 T1467 T1470 arg1Of Shi,","
R1020 T1471 T1470 arg2Of 2010,","
R1021 T1472 T1466 arg3Of ),(
R1022 T1473 T1474 arg1Of MicroRNA-21,is
R1023 T1473 T1475 arg2Of MicroRNA-21,considered
R1024 T1475 T1474 arg2Of considered,is
R1025 T1475 T1476 arg1Of considered,as
R1026 T1479 T1476 arg2Of factor,as
R1027 T1479 T1477 arg1Of factor,a
R1028 T1479 T1478 arg1Of factor,pro-survival
R1029 T1479 T1480 arg1Of factor,for
R1030 T1482 T1480 arg2Of cells,for
R1031 T1482 T1481 arg1Of cells,cancer
R1032 T1482 T1483 arg1Of cells,(
R1033 T1484 T1483 arg2Of Li,(
R1034 T1484 T1485 arg1Of Li,et
R1035 T1484 T1486 arg1Of Li,al.
R1036 T1484 T1487 arg1Of Li,","
R1037 T1488 T1487 arg2Of 2012,","
R1038 T1489 T1483 arg3Of ),(
R1039 T1490 T1491 arg1Of Integrins,play
R1040 T1491 T1494 arg1Of play,in
R1041 T1491 T1502 arg1Of play,and
R1042 T1493 T1491 arg2Of role,play
R1043 T1493 T1492 arg1Of role,a
R1044 T1496 T1494 arg2Of resistance,in
R1045 T1496 T1495 arg1Of resistance,the
R1046 T1496 T1497 arg1Of resistance,of
R1047 T1496 T1500 arg1Of resistance,to
R1048 T1499 T1497 arg2Of cancers,of
R1049 T1499 T1498 arg1Of cancers,advanced
R1050 T1501 T1500 arg2Of radiotherapy,to
R1051 T1502 T1511 arg1Of and,and
R1052 T1505 T1503 arg1Of integrin,chemotherapy.
R1053 T1505 T1504 arg1Of integrin,α5β1
R1054 T1505 T1507 arg1Of integrin,regulates
R1055 T1507 T1502 arg2Of regulates,and
R1056 T1507 T1506 arg1Of regulates,negatively
R1057 T1509 T1507 arg2Of signaling,regulates
R1058 T1509 T1508 arg1Of signaling,p53
R1059 T1511 T1510 arg1Of and,","
R1060 T1513 T1512 arg1Of event,the
R1061 T1513 T1514 arg1Of event,induces
R1062 T1514 T1511 arg2Of induces,and
R1063 T1517 T1514 arg2Of resistance,induces
R1064 T1517 T1515 arg1Of resistance,glioma
R1065 T1517 T1516 arg1Of resistance,cell
R1066 T1517 T1518 arg1Of resistance,to
R1067 T1519 T1518 arg2Of TMZ,to
R1068 T1519 T1520 arg1Of TMZ,(
R1069 T1519 T1529 modOf TMZ,ri
R1070 T1521 T1520 arg2Of Janouskova,(
R1071 T1521 T1522 arg1Of Janouskova,et
R1072 T1521 T1523 arg1Of Janouskova,al.
R1073 T1521 T1524 arg1Of Janouskova,","
R1074 T1525 T1524 arg2Of 2012,","
R1075 T1526 T1520 arg3Of ),(
R1076 T1528 T1527 arg1Of β1 integ,. α5
R1077 T1528 T1529 arg1Of β1 integ,ri
R1078 T1528 T1530 arg2Of β1 integ,n is consi
R1079 T1530 T1529 arg2Of n is consi,ri
R1080 T1530 T1531 arg1Of n is consi,de
R1081 T1534 T1531 arg2Of rapeut,de
R1082 T1534 T1532 arg1Of rapeut,r
R1083 T1534 T1533 arg1Of rapeut,ed as a the
R1084 T1534 T1535 arg1Of rapeut,ic
R1085 T1538 T1535 arg2Of grade ,ic
R1086 T1538 T1536 arg1Of grade ,target for
R1087 T1538 T1537 arg1Of grade ,high-
R1088 T1544 T1539 arg1Of alkylpurine-DNA-N-glycosylase,The
R1089 T1544 T1540 arg1Of alkylpurine-DNA-N-glycosylase,base
R1090 T1544 T1541 arg1Of alkylpurine-DNA-N-glycosylase,excision
R1091 T1544 T1542 arg1Of alkylpurine-DNA-N-glycosylase,repair
R1092 T1544 T1543 arg1Of alkylpurine-DNA-N-glycosylase,enzyme
R1093 T1544 T1545 arg1Of alkylpurine-DNA-N-glycosylase,(
R1094 T1544 T1548 arg1Of alkylpurine-DNA-N-glycosylase,","
R1095 T1544 T1549 arg1Of alkylpurine-DNA-N-glycosylase,which
R1096 T1544 T1550 arg1Of alkylpurine-DNA-N-glycosylase,repairs
R1097 T1544 T1559 arg1Of alkylpurine-DNA-N-glycosylase,participates
R1098 T1546 T1545 arg2Of APNG,(
R1099 T1547 T1545 arg3Of ),(
R1100 T1554 T1555 arg1Of N3-methyladenine,and
R1101 T1555 T1550 arg2Of and,repairs
R1102 T1555 T1551 arg1Of and,the
R1103 T1555 T1552 arg1Of and,cytotoxic
R1104 T1555 T1553 arg1Of and,lesions
R1105 T1556 T1555 arg2Of N7-methylguanine,and
R1106 T1559 T1557 arg1Of participates,","
R1107 T1559 T1558 arg1Of participates,also
R1108 T1559 T1560 arg1Of participates,in
R1109 T1559 T1564 arg1Of participates,(
R1110 T1563 T1560 arg2Of resistance,in
R1111 T1563 T1561 arg1Of resistance,the
R1112 T1563 T1562 arg1Of resistance,TMZ
R1113 T1565 T1564 arg2Of Agnihotri,(
R1114 T1565 T1566 arg1Of Agnihotri,et
R1115 T1565 T1567 arg1Of Agnihotri,al.
R1116 T1565 T1568 arg1Of Agnihotri,","
R1117 T1569 T1568 arg2Of 2012,","
R1118 T1570 T1564 arg3Of ),(
R1119 T1571 T1572 arg1Of Upregulation,of
R1120 T1571 T1577 modOf Upregulation,to
R1121 T1571 T1593 arg1Of Upregulation,contributes
R1122 T1576 T1572 arg2Of coupling,of
R1123 T1576 T1573 arg1Of coupling,mitochondrial
R1124 T1576 T1574 arg1Of coupling,respiratory
R1125 T1576 T1575 arg1Of coupling,chain
R1126 T1578 T1577 arg1Of suppress,to
R1127 T1580 T1578 arg2Of production,suppress
R1128 T1580 T1579 arg1Of production,the
R1129 T1580 T1581 arg1Of production,of
R1130 T1584 T1581 arg2Of species,of
R1131 T1584 T1582 arg1Of species,reactive
R1132 T1584 T1583 arg1Of species,oxygen
R1133 T1584 T1585 arg1Of species,(
R1134 T1584 T1588 arg2Of species,regulated
R1135 T1586 T1585 arg2Of ROS,(
R1136 T1587 T1585 arg3Of ),(
R1137 T1592 T1588 arg1Of oxidase,regulated
R1138 T1592 T1589 arg2Of oxidase,by
R1139 T1592 T1590 arg1Of oxidase,cytochrome
R1140 T1592 T1591 arg1Of oxidase,c
R1141 T1593 T1594 arg1Of contributes,in
R1142 T1593 T1596 arg1Of contributes,to
R1143 T1595 T1594 arg2Of part,in
R1144 T1598 T1596 arg2Of resistance,to
R1145 T1598 T1597 arg1Of resistance,TMZ
R1146 T1598 T1599 arg1Of resistance,in
R1147 T1600 T1599 arg2Of gliomas,in
R1148 T1600 T1601 arg1Of gliomas,(
R1149 T1602 T1601 arg2Of Oliva,(
R1150 T1602 T1603 arg1Of Oliva,et
R1151 T1602 T1604 arg1Of Oliva,al.
R1152 T1602 T1605 arg1Of Oliva,","
R1153 T1606 T1605 arg2Of 2011,","
R1154 T1607 T1601 arg3Of ),(

2_test

Id Subject Object Predicate Lexical cue
23459853-22837675-38778507 153-157 22837675 denotes 2012
23459853-20633539-38778508 419-423 20633539 denotes 2010
23459853-21909994-38778509 506-510 21909994 denotes 2012
23459853-22593187-38778510 729-733 22593187 denotes 2012
23459853-22156195-38778511 1021-1025 22156195 denotes 2012
23459853-21931801-38778512 1243-1247 21931801 denotes 2011

UBERON-AE

Id Subject Object Predicate Lexical cue
T874 803-808 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain

GO-BP

Id Subject Object Predicate Lexical cue
T2013 1158-1178 http://purl.obolibrary.org/obo/GO_0008535 denotes cytochrome c oxidase
T2012 1158-1178 http://purl.obolibrary.org/obo/GO_0004129 denotes cytochrome c oxidase
T2011 867-878 http://purl.obolibrary.org/obo/GO_0016798 denotes glycosylase
T2008 821-841 http://purl.obolibrary.org/obo/GO_0006284 denotes base excision repair
T2007 194-205 http://purl.obolibrary.org/obo/GO_0032259 denotes methylation
T2006 56-67 http://purl.obolibrary.org/obo/GO_0032259 denotes methylation
T2005 646-655 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T1996 220-224 http://purl.obolibrary.org/obo/GO_0003908 denotes MGMT
T1995 175-179 http://purl.obolibrary.org/obo/GO_0003908 denotes MGMT
T1994 78-82 http://purl.obolibrary.org/obo/GO_0003908 denotes MGMT
T1990 457-469 http://purl.obolibrary.org/obo/GO_0043066 denotes pro-survival
T1982 396-405 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis

GO-MF

Id Subject Object Predicate Lexical cue
T2033 1158-1178 http://purl.obolibrary.org/obo/GO_0004129 denotes cytochrome c oxidase
T2032 1158-1168 http://purl.obolibrary.org/obo/GO_0045158 denotes cytochrome
T2031 1158-1168 http://purl.obolibrary.org/obo/GO_0045157 denotes cytochrome
T2030 1158-1168 http://purl.obolibrary.org/obo/GO_0045156 denotes cytochrome
T2029 1158-1170 http://purl.obolibrary.org/obo/GO_0045155 denotes cytochrome c
T2028 1158-1168 http://purl.obolibrary.org/obo/GO_0045154 denotes cytochrome
T2027 1158-1168 http://purl.obolibrary.org/obo/GO_0045153 denotes cytochrome
T2026 867-878 http://purl.obolibrary.org/obo/GO_0016798 denotes glycosylase
T2023 220-224 http://purl.obolibrary.org/obo/GO_0003908 denotes MGMT
T2022 175-179 http://purl.obolibrary.org/obo/GO_0003908 denotes MGMT
T2021 78-82 http://purl.obolibrary.org/obo/GO_0003908 denotes MGMT

GO-CC

Id Subject Object Predicate Lexical cue
T2047 1058-1075 http://purl.obolibrary.org/obo/GO_0070469 denotes respiratory chain
T2046 1044-1075 http://purl.obolibrary.org/obo/GO_0097249 denotes mitochondrial respiratory chain
T2045 1044-1075 http://purl.obolibrary.org/obo/GO_0005746 denotes mitochondrial respiratory chain
T2038 488-493 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T2037 100-105 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

sentences

Id Subject Object Predicate Lexical cue
T897 1028-1249 Sentence denotes Upregulation of mitochondrial respiratory chain coupling to suppress the production of reactive oxygen species (ROS) regulated by cytochrome c oxidase contributes in part to TMZ resistance in gliomas (Oliva et al., 2011).
T896 817-1027 Sentence denotes The base excision repair enzyme alkylpurine-DNA-N-glycosylase (APNG), which repairs the cytotoxic lesions N3-methyladenine and N7-methylguanine, also participates in the TMZ resistance (Agnihotri et al., 2012).
T895 513-816 Sentence denotes Integrins play a role in the resistance of advanced cancers to radiotherapy and chemotherapy. α5β1 integrin negatively regulates p53 signaling, and the event induces glioma cell resistance to TMZ (Janouskova et al., 2012). α5β1 integrin is considered as a therapeutic target for high-grade brain tumors.
T894 426-512 Sentence denotes MicroRNA-21 is considered as a pro-survival factor for cancer cells (Li et al., 2012).
T893 279-425 Sentence denotes Intriguingly, overexpressed microRNA-21 reduces Bax/Bcl-2 ratio and caspase-3 activity, thereby blocking TMZ-induced apoptosis (Shi et al., 2010).
T892 160-278 Sentence denotes An increase in MGMT gene promoter methylation, which blocks MGMT protein expression, prolongs cancer patient survival.
T891 0-159 Sentence denotes Sensitivity to TMZ is significantly associated with the methylation status of MGMT gene promoter in cells committed to differentiation (Villalva et al., 2012).
T27 0-159 Sentence denotes Sensitivity to TMZ is significantly associated with the methylation status of MGMT gene promoter in cells committed to differentiation (Villalva et al., 2012).
T28 160-278 Sentence denotes An increase in MGMT gene promoter methylation, which blocks MGMT protein expression, prolongs cancer patient survival.
T29 279-425 Sentence denotes Intriguingly, overexpressed microRNA-21 reduces Bax/Bcl-2 ratio and caspase-3 activity, thereby blocking TMZ-induced apoptosis (Shi et al., 2010).
T30 426-512 Sentence denotes MicroRNA-21 is considered as a pro-survival factor for cancer cells (Li et al., 2012).
T31 513-816 Sentence denotes Integrins play a role in the resistance of advanced cancers to radiotherapy and chemotherapy. α5β1 integrin negatively regulates p53 signaling, and the event induces glioma cell resistance to TMZ (Janouskova et al., 2012). α5β1 integrin is considered as a therapeutic target for high-grade brain tumors.
T32 817-1027 Sentence denotes The base excision repair enzyme alkylpurine-DNA-N-glycosylase (APNG), which repairs the cytotoxic lesions N3-methyladenine and N7-methylguanine, also participates in the TMZ resistance (Agnihotri et al., 2012).
T33 1028-1249 Sentence denotes Upregulation of mitochondrial respiratory chain coupling to suppress the production of reactive oxygen species (ROS) regulated by cytochrome c oxidase contributes in part to TMZ resistance in gliomas (Oliva et al., 2011).

simple1

Id Subject Object Predicate Lexical cue
T2065 642-645 Protein denotes p53
T2064 426-437 Protein denotes MicroRNA-21
T2063 347-356 Protein denotes caspase-3
T2062 331-336 Protein denotes Bcl-2
T2061 327-330 Protein denotes Bax
T2060 307-318 Protein denotes microRNA-21
T2059 220-224 Protein denotes MGMT
T2058 175-179 Protein denotes MGMT
T2057 78-82 Protein denotes MGMT