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PMC:3585731 / 39990-41605 JSONTXT

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testone

Id Subject Object Predicate Lexical cue
T18170 394-398 Protein denotes TNFα
T18169 295-300 Protein denotes c-Jun
T18168 212-213 Protein denotes 2
T18167 207-211 Protein denotes JNK1
T18166 138-142 Protein denotes JNK2
T18165 129-133 Protein denotes JNK1
T18219 1417-1432 Phosphorylation denotes phosphorylation
T18218 1184-1193 Regulation denotes dependent
T18217 1064-1072 Positive_regulation denotes increase
T18216 988-998 Positive_regulation denotes activation
T18215 882-891 Regulation denotes autocrine
T18214 832-839 Negative_regulation denotes reduced
T18213 812-827 Phosphorylation denotes phosphorylation
T18212 757-766 Negative_regulation denotes knockdown
T18211 399-409 Gene_expression denotes production
T18210 381-390 Negative_regulation denotes reduction
T18209 276-291 Phosphorylation denotes phosphorylation
T18208 261-271 Negative_regulation denotes inhibiting
T18207 222-237 Phosphorylation denotes phosphorylation
T18206 194-203 Negative_regulation denotes knockdown
T18179 1436-1441 Protein denotes c-Jun
T18178 1277-1282 Protein denotes c-Jun
T18177 1150-1154 Protein denotes TNFα
T18176 1097-1102 Protein denotes c-Jun
T18175 922-927 Protein denotes c-Jun
T18174 892-896 Protein denotes TNFα
T18173 745-750 Protein denotes c-Jun
T18172 672-676 Protein denotes TNFα
T18171 637-642 Protein denotes c-Jun
R12087 T18167 T18206 themeOf JNK1,knockdown
R12088 T18168 T18206 themeOf 2,knockdown
R12089 T18169 T18209 themeOf c-Jun,phosphorylation
R12090 T18170 T18211 themeOf TNFα,production
R12091 T18173 T18212 themeOf c-Jun,knockdown
R12092 T18175 T18215 causeOf c-Jun,autocrine
R12093 T18176 T18217 themeOf c-Jun,increase
R12094 T18179 T18219 themeOf c-Jun,phosphorylation
R12103 T18209 T18208 themeOf phosphorylation,inhibiting
R12104 T18211 T18210 themeOf production,reduction
R12105 T18213 T18214 themeOf phosphorylation,reduced

2_test

Id Subject Object Predicate Lexical cue
23469174-22037377-90505457 105-107 22037377 denotes 43
23469174-20539307-90505458 688-690 20539307 denotes 13
23469174-15131264-90505459 694-696 15131264 denotes 14
23469174-22695613-90505460 700-702 22695613 denotes 15
23469174-19118012-90505461 1480-1482 19118012 denotes 44

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T19241 1607-1614 NN denotes effects
T19240 1596-1606 JJ denotes off-target
T19239 1586-1595 JJ denotes potantial
T19238 1583-1585 TO denotes to
T19237 1579-1582 JJ denotes due
T19236 1570-1578 NN denotes SP600125
T19235 1564-1569 VB denotes using
T19234 1559-1563 WRB denotes when
T19233 1551-1558 NN denotes caution
T19232 1547-1550 VB denotes use
T19231 1544-1546 TO denotes to
T19230 1539-1543 VB denotes need
T19229 1527-1538 NN denotes researchers
T19228 1525-1526 -COMMA- denotes ,
T19227 1517-1525 NN denotes addition
T19226 1514-1516 IN denotes In
T19225 1500-1512 RB denotes functionally
T19224 1488-1499 JJ denotes dispensable
T19223 1485-1487 CC denotes or
T19222 1483-1484 -RRB- denotes )
T19221 1482-1483 -RRB- denotes ]
T19220 1480-1482 CD denotes 44
T19219 1479-1480 -LRB- denotes [
T19218 1473-1478 VB denotes occur
T19217 1469-1472 MD denotes may
T19216 1463-1468 NN denotes Ser63
T19215 1458-1462 IN denotes than
T19214 1452-1457 JJ denotes other
T19213 1447-1451 NN denotes site
T19212 1445-1446 DT denotes a
T19211 1442-1444 IN denotes on
T19210 1436-1441 NN denotes c-Jun
T19209 1433-1435 IN denotes of
T19208 1417-1432 NN denotes phosphorylation
T19207 1412-1416 FW denotes e.g.
T19206 1411-1412 -LRB- denotes (
T19205 1401-1410 JJ denotes redundant
T19204 1394-1400 CC denotes either
T19203 1391-1393 VB denotes be
T19202 1387-1390 MD denotes may
T19201 1383-1386 CC denotes but
T19200 1381-1382 -COMMA- denotes ,
T19199 1371-1381 NN denotes activation
T19198 1363-1370 NN denotes pathway
T19197 1360-1362 IN denotes of
T19196 1353-1359 NN denotes marker
T19195 1346-1352 JJ denotes useful
T19194 1344-1345 DT denotes a
T19193 1341-1343 IN denotes as
T19192 1335-1340 VB denotes serve
T19191 1331-1334 MD denotes may
T19190 1322-1330 NN denotes activity
T19189 1318-1321 NN denotes JNK
T19188 1312-1317 IN denotes while
T19187 1310-1311 -COMMA- denotes ,
T19186 1299-1310 NN denotes necroptosis
T19185 1295-1298 IN denotes for
T19184 1286-1294 JJ denotes critical
T19183 1283-1285 VB denotes is
T19182 1277-1282 NN denotes c-Jun
T19181 1272-1276 IN denotes that
T19180 1261-1271 NN denotes conclusion
T19179 1251-1260 JJ denotes important
T19178 1247-1250 CC denotes but
T19177 1245-1246 -COMMA- denotes ,
T19176 1235-1245 JJ denotes unexpected
T19175 1232-1234 DT denotes an
T19174 1229-1231 TO denotes to
T19173 1226-1228 PRP denotes us
T19172 1222-1225 VB denotes led
T19171 1217-1221 NN denotes data
T19170 1213-1216 JJ denotes new
T19169 1207-1212 DT denotes These
T19168 1204-1205 -RRB- denotes )
T19167 1203-1204 NN denotes F
T19166 1202-1203 -COMMA- denotes ,
T19165 1200-1202 NN denotes 6E
T19164 1195-1199 NNP denotes Fig.
T19163 1194-1195 -LRB- denotes (
T19162 1179-1193 JJ denotes mTOR-dependent
T19161 1175-1178 CC denotes and
T19160 1171-1174 NN denotes Akt
T19159 1166-1170 CC denotes both
T19158 1162-1165 VB denotes was
T19157 1156-1161 WDT denotes which
T19156 1154-1155 -COMMA- denotes ,
T19155 1150-1154 NN denotes TNFα
T19154 1147-1149 CC denotes or
T19153 1138-1146 NN denotes zVAD.fmk
T19152 1133-1137 IN denotes with
T19151 1127-1132 NN denotes cells
T19150 1122-1126 NN denotes L929
T19149 1119-1121 IN denotes of
T19148 1109-1118 NN denotes treatment
T19147 1103-1108 IN denotes after
T19146 1097-1102 NN denotes c-Jun
T19145 1094-1096 IN denotes of
T19144 1088-1093 NN denotes level
T19143 1080-1087 NN denotes protein
T19142 1076-1079 DT denotes the
T19141 1073-1075 IN denotes in
T19140 1064-1072 NN denotes increase
T19139 1056-1063 JJ denotes overall
T19138 1053-1055 DT denotes an
T19137 1044-1052 VB denotes observed
T19136 1041-1043 PRP denotes we
T19135 1036-1040 IN denotes that
T19134 1031-1035 VB denotes note
T19133 1028-1030 TO denotes to
T19132 1018-1027 JJ denotes important
T19131 1013-1017 RB denotes also
T19130 1010-1012 VB denotes is
T19129 1007-1009 PRP denotes It
T19128 1002-1006 NNP denotes Akt.
T19127 999-1001 IN denotes of
T19126 988-998 NN denotes activation
T19125 980-987 VB denotes delayed
T19124 976-979 DT denotes the
T19123 973-975 TO denotes to
T19122 961-972 VB denotes contributes
T19121 956-960 WDT denotes that
T19120 951-955 NN denotes loop
T19119 942-950 NN denotes feedback
T19118 940-941 DT denotes a
T19117 933-939 VB denotes create
T19116 929-932 MD denotes may
T19115 927-928 -COMMA- denotes ,
T19114 922-927 NN denotes c-Jun
T19113 919-921 IN denotes on
T19112 909-918 JJ denotes dependent
T19111 907-908 -COMMA- denotes ,
T19110 897-907 NN denotes production
T19109 892-896 NN denotes TNFα
T19108 882-891 JJ denotes autocrine
T19107 880-881 -COMMA- denotes ,
T19106 876-880 RB denotes Thus
T19105 863-874 NN denotes necroptosis
T19104 860-862 IN denotes of
T19103 850-859 NN denotes induction
T19102 846-849 DT denotes the
T19101 840-845 IN denotes after
T19100 832-839 VB denotes reduced
T19099 828-831 VB denotes was
T19098 812-827 NN denotes phosphorylation
T19097 805-811 NN denotes Thr308
T19096 803-804 -COMMA- denotes ,
T19095 799-803 NN denotes case
T19094 794-798 DT denotes this
T19093 791-793 IN denotes in
T19092 789-790 -COMMA- denotes ,
T19091 782-789 RB denotes Notably
T19090 779-780 -RRB- denotes )
T19089 773-779 NN denotes S10H–J
T19088 768-772 NNP denotes Fig.
T19087 767-768 -LRB- denotes (
T19086 757-766 NN denotes knockdown
T19085 751-756 NN denotes siRNA
T19084 745-750 NN denotes c-Jun
T19083 739-744 VB denotes using
T19082 727-738 NN denotes conclusions
T19081 721-726 DT denotes these
T19080 711-720 VB denotes confirmed
T19079 708-710 PRP denotes we
T19078 704-707 CC denotes and
T19077 702-703 -RRB- denotes ]
T19076 700-702 CD denotes 15
T19075 699-700 -LRB- denotes [
T19074 697-698 -COMMA- denotes ,
T19073 696-697 -RRB- denotes ]
T19072 694-696 CD denotes 14
T19071 693-694 -LRB- denotes [
T19070 691-692 -COMMA- denotes ,
T19069 690-691 -RRB- denotes ]
T19068 688-690 CD denotes 13
T19067 687-688 -LRB- denotes [
T19066 677-686 NN denotes synthesis
T19065 672-676 NN denotes TNFα
T19064 662-671 JJ denotes autocrine
T19063 658-661 CC denotes and
T19062 646-657 NN denotes necroptosis
T19061 643-645 IN denotes in
T19060 637-642 NN denotes c-Jun
T19059 633-636 IN denotes for
T19058 628-632 NN denotes role
T19057 619-627 JJ denotes critical
T19056 617-618 DT denotes a
T19055 607-616 VB denotes suggested
T19054 602-606 RB denotes also
T19053 594-601 NN denotes reports
T19052 585-593 JJ denotes Previous
T19051 573-583 NN denotes inhibition
T19050 569-572 NN denotes JNK
T19049 564-568 IN denotes than
T19048 557-563 RB denotes rather
T19047 555-556 -COMMA- denotes ,
T19046 547-555 NN denotes molecule
T19045 542-546 DT denotes this
T19044 539-541 IN denotes of
T19043 531-538 NN denotes effects
T19042 520-530 JJ denotes off-target
T19041 512-519 VB denotes reflect
T19040 506-511 MD denotes could
T19039 504-505 -RRB- denotes )
T19038 503-504 CD denotes 2
T19037 498-502 NN denotes Fig.
T19036 497-498 -LRB- denotes (
T19035 486-496 NN denotes protection
T19034 477-485 NN denotes SP600125
T19033 472-476 IN denotes with
T19032 467-471 NN denotes data
T19031 459-466 JJ denotes earlier
T19030 454-458 IN denotes that
T19029 443-453 VB denotes suggesting
T19028 441-442 -COMMA- denotes ,
T19027 440-441 -RRB- denotes )
T19025 438-439 -COMMA- denotes ,
T19024 437-438 NNP denotes F
T19023 436-437 -COMMA- denotes ,
T19022 435-436 NNP denotes D
T19021 434-435 -COMMA- denotes ,
T19020 430-434 NN denotes S10C
T19019 425-429 NNP denotes Fig.
T19018 424-425 -LRB- denotes (
T19017 418-423 NN denotes death
T19016 413-417 NN denotes cell
T19015 410-412 CC denotes or
T19014 399-409 NN denotes production
T19013 394-398 NN denotes TNFα
T19012 391-393 IN denotes in
T19011 381-390 NN denotes reduction
T19010 379-380 DT denotes a
T19009 376-378 TO denotes to
T19008 371-375 VB denotes lead
T19007 369-370 -COMMA- denotes ,
T19006 362-369 RB denotes however
T19005 360-361 -COMMA- denotes ,
T19004 357-360 RB denotes not
T19003 353-356 VB denotes did
T19002 350-352 PRP denotes It
T19001 343-348 NN denotes model
T19000 339-342 PRP-DOLLAR- denotes our
T18999 334-338 IN denotes with
T18998 325-333 VB denotes agreeing
T18997 323-324 -COMMA- denotes ,
T18996 322-323 -RRB- denotes )
T18995 321-322 NN denotes E
T18994 320-321 -COMMA- denotes ,
T18993 316-320 NN denotes S10B
T18992 311-315 NNP denotes Fig.
T18991 310-311 -LRB- denotes (
T18990 304-309 NN denotes Ser63
T18989 301-303 IN denotes at
T18988 295-300 NN denotes c-Jun
T18987 292-294 IN denotes of
T18986 276-291 NN denotes phosphorylation
T18985 272-275 DT denotes the
T18984 261-271 VB denotes inhibiting
T18983 255-260 IN denotes while
T18982 248-254 NN denotes Thr308
T18981 245-247 IN denotes on
T18980 241-244 NN denotes Akt
T18979 238-240 IN denotes of
T18978 222-237 NN denotes phosphorylation
T18977 214-221 VB denotes allowed
T18976 207-213 NN denotes JNK1/2
T18975 204-206 IN denotes of
T18974 194-203 NN denotes knockdown
T18973 191-193 CC denotes or
T18972 180-190 NN denotes inhibition
T18971 171-179 JJ denotes specific
T18970 169-170 -COMMA- denotes ,
T18969 161-169 VB denotes expected
T18968 158-160 IN denotes As
T18967 155-156 -RRB- denotes )
T18966 149-155 NN denotes S10B–G
T18965 144-148 NN denotes Fig.
T18964 143-144 -LRB- denotes (
T18963 138-142 NN denotes JNK2
T18962 134-137 CC denotes and
T18961 129-133 NN denotes JNK1
T18960 121-128 IN denotes against
T18959 114-120 NN denotes siRNAs
T18958 110-113 CC denotes and
T18957 108-109 -COMMA- denotes ,
T18956 107-108 -RRB- denotes ]
T18955 105-107 CD denotes 43
T18954 104-105 -LRB- denotes [
T18953 99-103 CD denotes VIII
T18952 89-98 NN denotes inhibitor
T18951 85-88 NN denotes JNK
T18950 83-84 -COMMA- denotes ,
T18949 74-83 NN denotes inhibitor
T18948 70-73 NN denotes JNK
T18947 61-69 JJ denotes specific
T18946 56-60 RB denotes more
T18945 54-55 DT denotes a
T18944 51-53 TO denotes to
T18943 42-50 VB denotes switched
T18942 39-41 PRP denotes we
T18941 37-38 -COMMA- denotes ,
T18940 34-37 NN denotes JNK
T18939 31-33 IN denotes of
T18938 26-30 NN denotes role
T18937 22-25 DT denotes the
T18936 14-21 VB denotes examine
T18935 11-13 TO denotes to
T18934 9-10 -COMMA- denotes ,
T18933 0-9 RB denotes Therefore
T19026 439-440 NN denotes G
R12585 T18936 T18935 arg1Of examine,to
R12586 T18936 T18941 arg1Of examine,","
R12587 T18938 T18936 arg2Of role,examine
R12588 T18938 T18937 arg1Of role,the
R12589 T18938 T18939 arg1Of role,of
R12590 T18940 T18939 arg2Of JNK,of
R12591 T18942 T18936 arg1Of we,examine
R12592 T18942 T18943 arg1Of we,switched
R12593 T18943 T18933 arg1Of switched,Therefore
R12594 T18943 T18934 arg1Of switched,","
R12595 T18943 T18935 modOf switched,to
R12596 T18943 T18944 arg1Of switched,to
R12597 T18947 T18946 arg1Of specific,more
R12598 T18949 T18945 arg1Of inhibitor,a
R12599 T18949 T18947 arg1Of inhibitor,specific
R12600 T18949 T18948 arg1Of inhibitor,JNK
R12601 T18949 T18950 arg1Of inhibitor,","
R12602 T18949 T18958 arg1Of inhibitor,and
R12603 T18952 T18950 arg2Of inhibitor,","
R12604 T18952 T18951 arg1Of inhibitor,JNK
R12605 T18952 T18953 arg1Of inhibitor,VIII
R12606 T18952 T18954 arg1Of inhibitor,[
R12607 T18955 T18954 arg2Of 43,[
R12608 T18956 T18954 arg3Of ],[
R12609 T18958 T18944 arg2Of and,to
R12610 T18958 T18957 arg1Of and,","
R12611 T18959 T18958 arg2Of siRNAs,and
R12612 T18959 T18960 arg1Of siRNAs,against
R12613 T18961 T18962 arg1Of JNK1,and
R12614 T18962 T18960 arg2Of and,against
R12615 T18962 T18964 arg1Of and,(
R12616 T18963 T18962 arg2Of JNK2,and
R12617 T18966 T18964 arg2Of S10B–G,(
R12618 T18966 T18965 arg1Of S10B–G,Fig.
R12619 T18967 T18964 arg3Of ),(
R12620 T18969 T18968 arg2Of expected,As
R12621 T18972 T18973 arg1Of inhibition,or
R12622 T18973 T18971 arg1Of or,specific
R12623 T18973 T18975 arg1Of or,of
R12624 T18973 T18977 arg1Of or,allowed
R12625 T18973 T18984 arg1Of or,inhibiting
R12626 T18973 T18998 arg1Of or,agreeing
R12627 T18974 T18973 arg2Of knockdown,or
R12628 T18976 T18975 arg2Of JNK1/2,of
R12629 T18977 T18968 arg1Of allowed,As
R12630 T18977 T18970 arg1Of allowed,","
R12631 T18977 T18983 arg1Of allowed,while
R12632 T18977 T18991 arg1Of allowed,(
R12633 T18977 T18997 arg1Of allowed,","
R12634 T18977 T18998 modOf allowed,agreeing
R12635 T18978 T18977 arg2Of phosphorylation,allowed
R12636 T18978 T18979 arg1Of phosphorylation,of
R12637 T18978 T18981 arg1Of phosphorylation,on
R12638 T18980 T18979 arg2Of Akt,of
R12639 T18982 T18981 arg2Of Thr308,on
R12640 T18984 T18983 arg2Of inhibiting,while
R12641 T18986 T18984 arg2Of phosphorylation,inhibiting
R12642 T18986 T18985 arg1Of phosphorylation,the
R12643 T18986 T18987 arg1Of phosphorylation,of
R12644 T18986 T18989 arg1Of phosphorylation,at
R12645 T18988 T18987 arg2Of c-Jun,of
R12646 T18990 T18989 arg2Of Ser63,at
R12647 T18993 T18991 arg2Of S10B,(
R12648 T18993 T18992 arg1Of S10B,Fig.
R12649 T18993 T18994 arg1Of S10B,","
R12650 T18995 T18994 arg2Of E,","
R12651 T18996 T18991 arg3Of ),(
R12652 T18998 T18999 arg1Of agreeing,with
R12653 T19001 T18999 arg2Of model,with
R12654 T19001 T19000 arg1Of model,our
R12655 T19002 T19003 arg1Of It,did
R12656 T19002 T19008 arg1Of It,lead
R12657 T19008 T19003 arg2Of lead,did
R12658 T19008 T19004 arg1Of lead,not
R12659 T19008 T19005 arg1Of lead,","
R12660 T19008 T19006 arg1Of lead,however
R12661 T19008 T19007 arg1Of lead,","
R12662 T19008 T19009 arg1Of lead,to
R12663 T19008 T19018 arg1Of lead,(
R12664 T19008 T19028 arg1Of lead,","
R12665 T19008 T19029 modOf lead,suggesting
R12666 T19011 T19009 arg2Of reduction,to
R12667 T19011 T19010 arg1Of reduction,a
R12668 T19011 T19012 arg1Of reduction,in
R12669 T19014 T19013 arg1Of production,TNFα
R12670 T19014 T19015 arg1Of production,or
R12671 T19015 T19012 arg2Of or,in
R12672 T19017 T19015 arg2Of death,or
R12673 T19017 T19016 arg1Of death,cell
R12674 T19020 T19021 arg1Of S10C,","
R12675 T19021 T19023 arg1Of ",",","
R12676 T19022 T19021 arg2Of D,","
R12677 T19023 T19018 arg2Of ",",(
R12678 T19023 T19019 arg1Of ",",Fig.
R12679 T19023 T19025 arg1Of ",",","
R12680 T19024 T19023 arg2Of F,","
R12681 T19026 T19025 arg2Of G,","
R12682 T19027 T19018 arg3Of ),(
R12683 T19032 T19031 arg1Of data,earlier
R12684 T19032 T19033 arg1Of data,with
R12685 T19032 T19040 arg1Of data,could
R12686 T19032 T19041 arg1Of data,reflect
R12687 T19035 T19033 arg2Of protection,with
R12688 T19035 T19034 arg1Of protection,SP600125
R12689 T19035 T19036 arg1Of protection,(
R12690 T19037 T19036 arg2Of Fig.,(
R12691 T19037 T19038 arg1Of Fig.,2
R12692 T19039 T19036 arg3Of ),(
R12693 T19041 T19029 arg2Of reflect,suggesting
R12694 T19041 T19030 arg1Of reflect,that
R12695 T19041 T19040 arg2Of reflect,could
R12696 T19043 T19042 arg1Of effects,off-target
R12697 T19043 T19044 arg1Of effects,of
R12698 T19043 T19049 arg1Of effects,than
R12699 T19046 T19044 arg2Of molecule,of
R12700 T19046 T19045 arg1Of molecule,this
R12701 T19049 T19041 arg2Of than,reflect
R12702 T19049 T19047 arg1Of than,","
R12703 T19049 T19048 arg1Of than,rather
R12704 T19051 T19049 arg2Of inhibition,than
R12705 T19051 T19050 arg1Of inhibition,JNK
R12706 T19053 T19052 arg1Of reports,Previous
R12707 T19053 T19055 arg1Of reports,suggested
R12708 T19055 T19054 arg1Of suggested,also
R12709 T19055 T19070 arg1Of suggested,","
R12710 T19055 T19071 arg1Of suggested,[
R12711 T19055 T19074 arg1Of suggested,","
R12712 T19055 T19075 arg1Of suggested,[
R12713 T19055 T19078 arg1Of suggested,and
R12714 T19058 T19055 arg2Of role,suggested
R12715 T19058 T19056 arg1Of role,a
R12716 T19058 T19057 arg1Of role,critical
R12717 T19058 T19059 arg1Of role,for
R12718 T19058 T19061 arg1Of role,in
R12719 T19060 T19059 arg2Of c-Jun,for
R12720 T19062 T19063 arg1Of necroptosis,and
R12721 T19064 T19063 arg2Of autocrine,and
R12722 T19066 T19061 arg2Of synthesis,in
R12723 T19066 T19062 arg1Of synthesis,necroptosis
R12724 T19066 T19064 arg1Of synthesis,autocrine
R12725 T19066 T19065 arg1Of synthesis,TNFα
R12726 T19066 T19067 arg1Of synthesis,[
R12727 T19068 T19067 arg2Of 13,[
R12728 T19069 T19067 arg3Of ],[
R12729 T19072 T19071 arg2Of 14,[
R12730 T19073 T19071 arg3Of ],[
R12731 T19076 T19075 arg2Of 15,[
R12732 T19077 T19075 arg3Of ],[
R12733 T19079 T19080 arg1Of we,confirmed
R12734 T19080 T19078 arg2Of confirmed,and
R12735 T19082 T19080 arg2Of conclusions,confirmed
R12736 T19082 T19081 arg1Of conclusions,these
R12737 T19082 T19083 arg1Of conclusions,using
R12738 T19086 T19083 arg2Of knockdown,using
R12739 T19086 T19084 arg1Of knockdown,c-Jun
R12740 T19086 T19085 arg1Of knockdown,siRNA
R12741 T19086 T19087 arg1Of knockdown,(
R12742 T19089 T19087 arg2Of S10H–J,(
R12743 T19089 T19088 arg1Of S10H–J,Fig.
R12744 T19090 T19087 arg3Of ),(
R12745 T19095 T19093 arg2Of case,in
R12746 T19095 T19094 arg1Of case,this
R12747 T19098 T19097 arg1Of phosphorylation,Thr308
R12748 T19098 T19099 arg1Of phosphorylation,was
R12749 T19098 T19100 arg2Of phosphorylation,reduced
R12750 T19100 T19091 arg1Of reduced,Notably
R12751 T19100 T19092 arg1Of reduced,","
R12752 T19100 T19093 arg1Of reduced,in
R12753 T19100 T19096 arg1Of reduced,","
R12754 T19100 T19099 arg2Of reduced,was
R12755 T19100 T19101 arg1Of reduced,after
R12756 T19103 T19101 arg2Of induction,after
R12757 T19103 T19102 arg1Of induction,the
R12758 T19103 T19104 arg1Of induction,of
R12759 T19105 T19104 arg2Of necroptosis,of
R12760 T19110 T19108 arg1Of production,autocrine
R12761 T19110 T19109 arg1Of production,TNFα
R12762 T19110 T19111 arg1Of production,","
R12763 T19110 T19112 arg1Of production,dependent
R12764 T19110 T19116 arg1Of production,may
R12765 T19110 T19117 arg1Of production,create
R12766 T19112 T19113 arg1Of dependent,on
R12767 T19114 T19113 arg2Of c-Jun,on
R12768 T19117 T19106 arg1Of create,Thus
R12769 T19117 T19107 arg1Of create,","
R12770 T19117 T19115 arg1Of create,","
R12771 T19117 T19116 arg2Of create,may
R12772 T19120 T19117 arg2Of loop,create
R12773 T19120 T19118 arg1Of loop,a
R12774 T19120 T19119 arg1Of loop,feedback
R12775 T19120 T19121 arg1Of loop,that
R12776 T19120 T19122 arg1Of loop,contributes
R12777 T19122 T19123 arg1Of contributes,to
R12778 T19126 T19123 arg2Of activation,to
R12779 T19126 T19124 arg1Of activation,the
R12780 T19126 T19125 arg2Of activation,delayed
R12781 T19126 T19127 arg1Of activation,of
R12782 T19128 T19127 arg2Of Akt.,of
R12783 T19130 T19122 arg2Of is,contributes
R12784 T19130 T19131 arg1Of is,also
R12785 T19132 T19130 arg2Of important,is
R12786 T19134 T19129 arg1Of note,It
R12787 T19134 T19130 arg1Of note,is
R12788 T19134 T19132 arg1Of note,important
R12789 T19134 T19133 arg1Of note,to
R12790 T19136 T19137 arg1Of we,observed
R12791 T19137 T19134 arg2Of observed,note
R12792 T19137 T19135 arg1Of observed,that
R12793 T19137 T19147 arg1Of observed,after
R12794 T19140 T19137 arg2Of increase,observed
R12795 T19140 T19138 arg1Of increase,an
R12796 T19140 T19139 arg1Of increase,overall
R12797 T19140 T19141 arg1Of increase,in
R12798 T19144 T19141 arg2Of level,in
R12799 T19144 T19142 arg1Of level,the
R12800 T19144 T19143 arg1Of level,protein
R12801 T19144 T19145 arg1Of level,of
R12802 T19146 T19145 arg2Of c-Jun,of
R12803 T19148 T19147 arg2Of treatment,after
R12804 T19148 T19149 arg1Of treatment,of
R12805 T19148 T19152 arg1Of treatment,with
R12806 T19151 T19149 arg2Of cells,of
R12807 T19151 T19150 arg1Of cells,L929
R12808 T19153 T19154 arg1Of zVAD.fmk,or
R12809 T19154 T19152 arg2Of or,with
R12810 T19154 T19156 arg1Of or,","
R12811 T19154 T19157 arg1Of or,which
R12812 T19154 T19158 arg1Of or,was
R12813 T19155 T19154 arg2Of TNFα,or
R12814 T19160 T19161 arg1Of Akt,and
R12815 T19161 T19158 arg2Of and,was
R12816 T19161 T19159 arg1Of and,both
R12817 T19161 T19163 arg1Of and,(
R12818 T19162 T19161 arg2Of mTOR-dependent,and
R12819 T19165 T19163 arg2Of 6E,(
R12820 T19165 T19164 arg1Of 6E,Fig.
R12821 T19165 T19166 arg1Of 6E,","
R12822 T19167 T19166 arg2Of F,","
R12823 T19168 T19163 arg3Of ),(
R12824 T19171 T19169 arg1Of data,These
R12825 T19171 T19170 arg1Of data,new
R12826 T19171 T19172 arg1Of data,led
R12827 T19172 T19174 arg1Of led,to
R12828 T19173 T19172 arg2Of us,led
R12829 T19176 T19178 arg1Of unexpected,but
R12830 T19178 T19177 arg1Of but,","
R12831 T19179 T19178 arg2Of important,but
R12832 T19180 T19174 arg2Of conclusion,to
R12833 T19180 T19175 arg1Of conclusion,an
R12834 T19180 T19176 arg1Of conclusion,unexpected
R12835 T19180 T19179 arg1Of conclusion,important
R12836 T19182 T19183 arg1Of c-Jun,is
R12837 T19182 T19184 arg1Of c-Jun,critical
R12838 T19183 T19180 arg2Of is,conclusion
R12839 T19183 T19181 arg1Of is,that
R12840 T19183 T19187 arg1Of is,","
R12841 T19183 T19188 arg1Of is,while
R12842 T19184 T19183 arg2Of critical,is
R12843 T19184 T19185 arg1Of critical,for
R12844 T19186 T19185 arg2Of necroptosis,for
R12845 T19190 T19189 arg1Of activity,JNK
R12846 T19190 T19191 arg1Of activity,may
R12847 T19190 T19192 arg1Of activity,serve
R12848 T19190 T19202 arg1Of activity,may
R12849 T19190 T19203 arg1Of activity,be
R12850 T19190 T19205 arg1Of activity,redundant
R12851 T19190 T19224 arg1Of activity,dispensable
R12852 T19192 T19191 arg2Of serve,may
R12853 T19192 T19193 arg1Of serve,as
R12854 T19192 T19201 arg1Of serve,but
R12855 T19196 T19193 arg2Of marker,as
R12856 T19196 T19194 arg1Of marker,a
R12857 T19196 T19195 arg1Of marker,useful
R12858 T19196 T19197 arg1Of marker,of
R12859 T19199 T19197 arg2Of activation,of
R12860 T19199 T19198 arg1Of activation,pathway
R12861 T19201 T19188 arg2Of but,while
R12862 T19201 T19200 arg1Of but,","
R12863 T19203 T19201 arg2Of be,but
R12864 T19203 T19202 arg2Of be,may
R12865 T19205 T19204 arg1Of redundant,either
R12866 T19205 T19206 arg1Of redundant,(
R12867 T19205 T19223 arg1Of redundant,or
R12868 T19208 T19207 arg1Of phosphorylation,e.g.
R12869 T19208 T19209 arg1Of phosphorylation,of
R12870 T19208 T19211 arg1Of phosphorylation,on
R12871 T19208 T19217 arg1Of phosphorylation,may
R12872 T19208 T19218 arg1Of phosphorylation,occur
R12873 T19210 T19209 arg2Of c-Jun,of
R12874 T19213 T19211 arg2Of site,on
R12875 T19213 T19212 arg1Of site,a
R12876 T19213 T19214 arg1Of site,other
R12877 T19214 T19215 arg1Of other,than
R12878 T19216 T19215 arg2Of Ser63,than
R12879 T19218 T19206 arg2Of occur,(
R12880 T19218 T19217 arg2Of occur,may
R12881 T19218 T19219 arg1Of occur,[
R12882 T19220 T19219 arg2Of 44,[
R12883 T19221 T19219 arg3Of ],[
R12884 T19222 T19206 arg3Of ),(
R12885 T19223 T19203 arg2Of or,be
R12886 T19224 T19223 arg2Of dispensable,or
R12887 T19224 T19225 arg1Of dispensable,functionally
R12888 T19227 T19226 arg2Of addition,In
R12889 T19229 T19230 arg1Of researchers,need
R12890 T19229 T19232 arg1Of researchers,use
R12891 T19229 T19235 arg1Of researchers,using
R12892 T19230 T19226 arg1Of need,In
R12893 T19230 T19228 arg1Of need,","
R12894 T19232 T19230 arg2Of use,need
R12895 T19232 T19231 arg1Of use,to
R12896 T19232 T19234 arg1Of use,when
R12897 T19233 T19232 arg2Of caution,use
R12898 T19235 T19234 arg2Of using,when
R12899 T19236 T19235 arg2Of SP600125,using
R12900 T19236 T19237 arg1Of SP600125,due
R12901 T19237 T19238 arg1Of due,to
R12902 T19241 T19238 arg2Of effects,to
R12903 T19241 T19239 arg1Of effects,potantial
R12904 T19241 T19240 arg1Of effects,off-target

bionlp-st-ge-2016-coref

Id Subject Object Predicate Lexical cue
T18387 1064-1072 Antecedent denotes increase
T18386 1156-1161 Anaphor denotes which
R12163 T18386 T18387 boundBy which,increase

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T18413 1436-1441 Protein denotes c-Jun
T18412 1277-1282 Protein denotes c-Jun
T18411 1150-1154 Protein denotes TNFα
T18410 1097-1102 Protein denotes c-Jun
T18409 922-927 Protein denotes c-Jun
T18408 892-896 Protein denotes TNFα
T18407 745-750 Protein denotes c-Jun
T18406 672-676 Protein denotes TNFα
T18405 637-642 Protein denotes c-Jun
T18404 394-398 Protein denotes TNFα
T18403 295-300 Protein denotes c-Jun
T18402 212-213 Protein denotes 2
T18401 207-211 Protein denotes JNK1
T18400 138-142 Protein denotes JNK2
T18399 129-133 Protein denotes JNK1

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T19398 1179-1183 http://www.uniprot.org/uniprot/P42345 denotes mTOR
T19397 1436-1441 http://www.uniprot.org/uniprot/P05412 denotes c-Jun
T19396 1277-1282 http://www.uniprot.org/uniprot/P05412 denotes c-Jun
T19395 1097-1102 http://www.uniprot.org/uniprot/P05412 denotes c-Jun
T19394 922-927 http://www.uniprot.org/uniprot/P05412 denotes c-Jun
T19393 745-750 http://www.uniprot.org/uniprot/P05412 denotes c-Jun
T19392 637-642 http://www.uniprot.org/uniprot/P05412 denotes c-Jun
T19391 295-300 http://www.uniprot.org/uniprot/P05412 denotes c-Jun
T19390 1150-1154 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T19389 892-896 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T19388 672-676 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T19387 394-398 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T19384 1171-1174 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T19383 1002-1005 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T19382 241-244 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T19362 1171-1174 http://www.uniprot.org/uniprot/P31751 denotes Akt
T19361 1002-1005 http://www.uniprot.org/uniprot/P31751 denotes Akt
T19340 1171-1174 http://www.uniprot.org/uniprot/P31749 denotes Akt
T19339 1002-1005 http://www.uniprot.org/uniprot/P31749 denotes Akt
T19338 241-244 http://www.uniprot.org/uniprot/P31749 denotes Akt
T19360 241-244 http://www.uniprot.org/uniprot/P31751 denotes Akt

GO-BP

Id Subject Object Predicate Lexical cue
T18468 677-686 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T18466 418-423 http://purl.obolibrary.org/obo/GO_0016265 denotes death
T18462 413-423 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T18453 1417-1432 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T18452 812-827 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T18451 276-291 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T18450 222-237 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T18442 1299-1310 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T18441 863-874 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T18440 646-657 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T18434 850-874 http://purl.obolibrary.org/obo/GO_0070266 denotes induction of necroptosis
T18432 863-874 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T18431 646-657 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T18421 1318-1321 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T18420 569-572 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T18419 85-88 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T18418 70-73 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T18417 34-37 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK

GO-MF

Id Subject Object Predicate Lexical cue
T18478 1318-1321 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T18477 569-572 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T18476 85-88 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T18475 70-73 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T18474 34-37 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK

GO-CC

Id Subject Object Predicate Lexical cue
T18486 1127-1132 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

sentences

Id Subject Object Predicate Lexical cue
T18334 1514-1615 Sentence denotes In addition, researchers need to use caution when using SP600125 due to potantial off-target effects.
T18333 1207-1513 Sentence denotes These new data led us to an unexpected, but important conclusion that c-Jun is critical for necroptosis, while JNK activity may serve as a useful marker of pathway activation, but may be either redundant (e.g. phosphorylation of c-Jun on a site other than Ser63 may occur [44]) or dispensable functionally.
T18332 876-1206 Sentence denotes Thus, autocrine TNFα production, dependent on c-Jun, may create a feedback loop that contributes to the delayed activation of Akt. It is also important to note that we observed an overall increase in the protein level of c-Jun after treatment of L929 cells with zVAD.fmk or TNFα, which was both Akt and mTOR-dependent (Fig. 6E,F).
T18331 782-875 Sentence denotes Notably, in this case, Thr308 phosphorylation was reduced after the induction of necroptosis.
T18330 585-781 Sentence denotes Previous reports also suggested a critical role for c-Jun in necroptosis and autocrine TNFα synthesis [13], [14], [15] and we confirmed these conclusions using c-Jun siRNA knockdown (Fig. S10H–J).
T18329 350-584 Sentence denotes It did not, however, lead to a reduction in TNFα production or cell death (Fig. S10C,D,F,G), suggesting that earlier data with SP600125 protection (Fig. 2) could reflect off-target effects of this molecule, rather than JNK inhibition.
T18328 158-349 Sentence denotes As expected, specific inhibition or knockdown of JNK1/2 allowed phosphorylation of Akt on Thr308 while inhibiting the phosphorylation of c-Jun at Ser63 (Fig. S10B,E), agreeing with our model.
T18327 0-157 Sentence denotes Therefore, to examine the role of JNK, we switched to a more specific JNK inhibitor, JNK inhibitor VIII [43], and siRNAs against JNK1 and JNK2 (Fig. S10B–G).
T248 0-157 Sentence denotes Therefore, to examine the role of JNK, we switched to a more specific JNK inhibitor, JNK inhibitor VIII [43], and siRNAs against JNK1 and JNK2 (Fig. S10B–G).
T249 158-349 Sentence denotes As expected, specific inhibition or knockdown of JNK1/2 allowed phosphorylation of Akt on Thr308 while inhibiting the phosphorylation of c-Jun at Ser63 (Fig. S10B,E), agreeing with our model.
T250 350-584 Sentence denotes It did not, however, lead to a reduction in TNFα production or cell death (Fig. S10C,D,F,G), suggesting that earlier data with SP600125 protection (Fig. 2) could reflect off-target effects of this molecule, rather than JNK inhibition.
T251 585-781 Sentence denotes Previous reports also suggested a critical role for c-Jun in necroptosis and autocrine TNFα synthesis [13], [14], [15] and we confirmed these conclusions using c-Jun siRNA knockdown (Fig. S10H–J).
T252 782-875 Sentence denotes Notably, in this case, Thr308 phosphorylation was reduced after the induction of necroptosis.
T253 876-1006 Sentence denotes Thus, autocrine TNFα production, dependent on c-Jun, may create a feedback loop that contributes to the delayed activation of Akt.
T254 1007-1206 Sentence denotes It is also important to note that we observed an overall increase in the protein level of c-Jun after treatment of L929 cells with zVAD.fmk or TNFα, which was both Akt and mTOR-dependent (Fig. 6E,F).
T255 1207-1513 Sentence denotes These new data led us to an unexpected, but important conclusion that c-Jun is critical for necroptosis, while JNK activity may serve as a useful marker of pathway activation, but may be either redundant (e.g. phosphorylation of c-Jun on a site other than Ser63 may occur [44]) or dispensable functionally.
T256 1514-1615 Sentence denotes In addition, researchers need to use caution when using SP600125 due to potantial off-target effects.

simple1

Id Subject Object Predicate Lexical cue
T18516 1436-1441 Protein denotes c-Jun
T18515 1277-1282 Protein denotes c-Jun
T18514 1150-1154 Protein denotes TNFα
T18513 1097-1102 Protein denotes c-Jun
T18512 922-927 Protein denotes c-Jun
T18511 892-896 Protein denotes TNFα
T18510 745-750 Protein denotes c-Jun
T18509 672-676 Protein denotes TNFα
T18508 637-642 Protein denotes c-Jun
T18507 394-398 Protein denotes TNFα
T18506 295-300 Protein denotes c-Jun
T18505 212-213 Protein denotes 2
T18504 207-211 Protein denotes JNK1
T18503 138-142 Protein denotes JNK2
T18502 129-133 Protein denotes JNK1

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T19313 1417-1432 Phosphorylation denotes phosphorylation
T19312 1064-1072 Positive_regulation denotes increase
T19311 909-918 Regulation denotes dependent
T19310 897-907 Gene_expression denotes production
T19309 757-766 Negative_regulation denotes knockdown
T19308 677-686 Gene_expression denotes synthesis
T19307 628-632 Positive_regulation denotes role
T19306 381-390 Negative_regulation denotes reduction
T19305 399-409 Gene_expression denotes production
T19304 276-291 Phosphorylation denotes phosphorylation
T19303 261-271 Negative_regulation denotes inhibiting
T19302 180-190 Negative_regulation denotes inhibition
T19301 194-203 Negative_regulation denotes knockdown
T19293 1436-1441 Protein denotes c-Jun
T19292 1277-1282 Protein denotes c-Jun
T19291 1150-1154 Protein denotes TNFα
T19290 1097-1102 Protein denotes c-Jun
T19289 922-927 Protein denotes c-Jun
T19288 892-896 Protein denotes TNFα
T19287 745-750 Protein denotes c-Jun
T19286 672-676 Protein denotes TNFα
T19285 637-642 Protein denotes c-Jun
T19284 394-398 Protein denotes TNFα
T19283 295-300 Protein denotes c-Jun
T19282 212-213 Protein denotes 2
T19281 207-211 Protein denotes JNK1
T19280 138-142 Protein denotes JNK2
T19279 129-133 Protein denotes JNK1
R12911 T19281 T19302 themeOf JNK1,inhibition
R12912 T19281 T19301 themeOf JNK1,knockdown
R12913 T19282 T19302 themeOf 2,inhibition
R12914 T19282 T19301 themeOf 2,knockdown
R12915 T19283 T19304 themeOf c-Jun,phosphorylation
R12916 T19284 T19305 themeOf TNFα,production
R12917 T19285 T19307 causeOf c-Jun,role
R12918 T19286 T19308 themeOf TNFα,synthesis
R12919 T19287 T19309 themeOf c-Jun,knockdown
R12920 T19288 T19310 themeOf TNFα,production
R12921 T19289 T19311 causeOf c-Jun,dependent
R12922 T19290 T19312 themeOf c-Jun,increase
R12923 T19293 T19313 themeOf c-Jun,phosphorylation
R12926 T19302 T19301 themeOf inhibition,knockdown
R12927 T19302 T19301 themeOf inhibition,knockdown
R12928 T19304 T19303 themeOf phosphorylation,inhibiting
R12929 T19305 T19306 themeOf production,reduction
R12930 T19308 T19307 themeOf synthesis,role
R12931 T19310 T19311 themeOf production,dependent

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T19537 1417-1432 Phosphorylation denotes phosphorylation
T19536 1064-1072 Positive_regulation denotes increase
T19535 909-918 Positive_regulation denotes dependent
T19534 897-907 Gene_expression denotes production
T19533 882-891 Positive_regulation denotes autocrine
T19532 757-766 Negative_regulation denotes knockdown
T19531 677-686 Gene_expression denotes synthesis
T19510 745-750 Protein denotes c-Jun
T19509 672-676 Protein denotes TNFα
T19508 637-642 Protein denotes c-Jun
T19507 394-398 Protein denotes TNFα
T19506 295-300 Protein denotes c-Jun
T19505 212-213 Protein denotes 2
T19504 207-211 Protein denotes JNK1
T19503 138-142 Protein denotes JNK2
T19502 129-133 Protein denotes JNK1
T19516 1436-1441 Protein denotes c-Jun
T19515 1277-1282 Protein denotes c-Jun
T19514 1150-1154 Protein denotes TNFα
T19513 1097-1102 Protein denotes c-Jun
T19512 922-927 Protein denotes c-Jun
T19511 892-896 Protein denotes TNFα
T19530 381-390 Negative_regulation denotes reduction
T19529 399-409 Gene_expression denotes production
T19528 194-203 Negative_regulation denotes knockdown
T19527 276-291 Phosphorylation denotes phosphorylation
T19526 180-190 Negative_regulation denotes inhibition
T19525 261-271 Negative_regulation denotes inhibiting
R12980 T19504 T19526 themeOf JNK1,inhibition
R12981 T19504 T19528 themeOf JNK1,knockdown
R12982 T19505 T19526 themeOf 2,inhibition
R12983 T19505 T19528 themeOf 2,knockdown
R12984 T19506 T19527 themeOf c-Jun,phosphorylation
R12985 T19507 T19529 themeOf TNFα,production
R12986 T19509 T19531 themeOf TNFα,synthesis
R12987 T19510 T19532 themeOf c-Jun,knockdown
R12988 T19511 T19534 themeOf TNFα,production
R12989 T19512 T19535 causeOf c-Jun,dependent
R12990 T19513 T19536 themeOf c-Jun,increase
R12991 T19516 T19537 themeOf c-Jun,phosphorylation
R12994 T19526 T19528 themeOf inhibition,knockdown
R12995 T19526 T19528 themeOf inhibition,knockdown
R12996 T19527 T19525 themeOf phosphorylation,inhibiting
R12997 T19529 T19530 themeOf production,reduction
R12998 T19534 T19533 themeOf production,autocrine
R12999 T19534 T19535 themeOf production,dependent

DLUT931

Id Subject Object Predicate Lexical cue
T19424 1436-1441 Protein denotes c-Jun
T19423 1277-1282 Protein denotes c-Jun
T19422 1150-1154 Protein denotes TNFα
T19421 1097-1102 Protein denotes c-Jun
T19420 922-927 Protein denotes c-Jun
T19419 892-896 Protein denotes TNFα
T19418 745-750 Protein denotes c-Jun
T19417 672-676 Protein denotes TNFα
T19416 637-642 Protein denotes c-Jun
T19415 394-398 Protein denotes TNFα
T19414 295-300 Protein denotes c-Jun
T19413 212-213 Protein denotes 2
T19412 207-211 Protein denotes JNK1
T19411 138-142 Protein denotes JNK2
T19410 129-133 Protein denotes JNK1
T19444 1417-1432 Phosphorylation denotes phosphorylation
T19443 1064-1072 Positive_regulation denotes increase
T19442 882-891 Positive_regulation denotes autocrine
T19441 909-918 Positive_regulation denotes dependent
T19440 897-907 Gene_expression denotes production
T19439 751-756 Negative_regulation denotes siRNA
T19438 757-766 Negative_regulation denotes knockdown
T19437 662-671 Positive_regulation denotes autocrine
T19436 381-390 Negative_regulation denotes reduction
T19435 399-409 Gene_expression denotes production
T19434 276-291 Phosphorylation denotes phosphorylation
R12939 T19414 T19434 themeOf c-Jun,phosphorylation
R12940 T19415 T19435 themeOf TNFα,production
R12941 T19417 T19437 themeOf TNFα,autocrine
R12942 T19418 T19438 themeOf c-Jun,knockdown
R12943 T19419 T19440 themeOf TNFα,production
R12944 T19420 T19441 causeOf c-Jun,dependent
R12945 T19421 T19443 themeOf c-Jun,increase
R12946 T19424 T19444 themeOf c-Jun,phosphorylation
R12949 T19435 T19436 themeOf production,reduction
R12950 T19438 T19439 themeOf knockdown,siRNA
R12951 T19439 T19438 themeOf siRNA,knockdown
R12952 T19440 T19441 themeOf production,dependent
R12953 T19440 T19442 themeOf production,autocrine

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T19899 882-928 Regulation denotes autocrine TNFα production, dependent on c-Jun,
T19896 222-244 Phosphorylation denotes phosphorylation of Akt
T19895 976-1005 Positive_regulation denotes the delayed activation of Akt
T19894 272-309 Phosphorylation denotes the phosphorylation of c-Jun at Ser63
T19891 882-928 Gene_expression denotes autocrine TNFα production, dependent on c-Jun,
T19887 569-583 Negative_regulation denotes JNK inhibition
T19885 1417-1441 Phosphorylation denotes phosphorylation of c-Jun
T19882 976-1005 Negative_regulation denotes the delayed activation of Akt
T19880 394-409 Gene_expression denotes TNFα production
T19879 1272-1282 Protein denotes that c-Jun
T19876 54-109 Entity denotes a more specific JNK inhibitor, JNK inhibitor VIII [43],
T19873 437-441 Entity denotes F,G)
T19872 1433-1441 Protein denotes of c-Jun
T19869 1097-1102 Protein denotes c-Jun
T19867 212-213 Protein denotes 2
T19866 207-213 Protein denotes JNK1/2
T19864 892-896 Protein denotes TNFα
T19862 639-703 Protein denotes Jun in necroptosis and autocrine TNFα synthesis [13], [14], [15]
T19859 248-254 Entity denotes Thr308
T19855 85-108 Entity denotes JNK inhibitor VIII [43]
T19853 1179-1193 Protein denotes mTOR-dependent
T19850 394-398 Protein denotes TNFα
T19848 745-750 Protein denotes c-Jun
T19847 304-309 Entity denotes Ser63
T19842 207-213 Protein denotes JNK1/2
T19837 292-300 Protein denotes of c-Jun
T19836 1570-1578 Entity denotes SP600125
T19833 662-703 Protein denotes autocrine TNFα synthesis [13], [14], [15]
T19832 425-428 Protein denotes Fig
T19828 129-133 Protein denotes JNK1
T19824 569-572 Protein denotes JNK
T19821 238-244 Protein denotes of Akt
T19819 138-142 Protein denotes JNK2
T19818 542-555 Entity denotes this molecule
T19817 805-811 Entity denotes Thr308
T19816 70-73 Protein denotes JNK
T19813 85-108 Protein denotes JNK inhibitor VIII [43]
T19809 1445-1451 Entity denotes a site
T19808 85-88 Protein denotes JNK
T19807 1138-1146 Entity denotes zVAD.fmk
T19806 999-1005 Protein denotes of Akt
T19805 144-155 Protein denotes Fig. S10B–G
T19803 1171-1174 Protein denotes Akt
T19798 1150-1154 Protein denotes TNFα
T19797 1318-1321 Protein denotes JNK
T19791 919-927 Protein denotes on c-Jun
T19780 1463-1468 Entity denotes Ser63
T19779 31-37 Protein denotes of JNK
T19778 1073-1087 Protein denotes in the protein
T19775 498-501 Protein denotes Fig
R13129 T19791 T19899 causeOf on c-Jun,"autocrine TNFα production, dependent on c-Jun,"
R13130 T19806 T19895 themeOf of Akt,the delayed activation of Akt
R13132 T19821 T19896 themeOf of Akt,phosphorylation of Akt
R13133 T19824 T19887 themeOf JNK,JNK inhibition
R13138 T19837 T19894 themeOf of c-Jun,the phosphorylation of c-Jun at Ser63
R13140 T19847 T19837 partOf Ser63,of c-Jun
R13141 T19847 T19894 siteOf Ser63,the phosphorylation of c-Jun at Ser63
R13142 T19850 T19880 themeOf TNFα,TNFα production
R13146 T19864 T19891 themeOf TNFα,"autocrine TNFα production, dependent on c-Jun,"
R13147 T19872 T19885 themeOf of c-Jun,phosphorylation of c-Jun
R13150 T19891 T19899 themeOf "autocrine TNFα production, dependent on c-Jun,","autocrine TNFα production, dependent on c-Jun,"
R13152 T19895 T19882 themeOf the delayed activation of Akt,the delayed activation of Akt

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T20404 334-338 IN denotes with
T20657 1614-1615 . denotes .
T20656 1607-1614 NNS denotes effects
T20655 1596-1606 JJ denotes off-target
T20654 1586-1595 JJ denotes potantial
T20653 1583-1585 TO denotes to
T20652 1579-1582 JJ denotes due
T20651 1570-1578 CD denotes SP600125
T20650 1564-1569 VBG denotes using
T20649 1559-1563 WRB denotes when
T20648 1551-1558 NN denotes caution
T20647 1547-1550 VB denotes use
T20646 1544-1546 TO denotes to
T20645 1539-1543 VBP denotes need
T20644 1527-1538 NNS denotes researchers
T20643 1525-1526 , denotes ,
T20642 1517-1525 NN denotes addition
T20641 1514-1516 IN denotes In
T20640 1512-1513 . denotes .
T20639 1500-1512 RB denotes functionally
T20638 1488-1499 JJ denotes dispensable
T20637 1485-1487 CC denotes or
T20636 1483-1484 -RRB- denotes )
T20635 1482-1483 NNP denotes ]
T20634 1480-1482 CD denotes 44
T20633 1479-1480 NNP denotes [
T20632 1473-1478 VB denotes occur
T20631 1469-1472 MD denotes may
T20630 1463-1468 CD denotes Ser63
T20629 1458-1462 IN denotes than
T20628 1452-1457 JJ denotes other
T20627 1447-1451 NN denotes site
T20626 1445-1446 DT denotes a
T20625 1442-1444 IN denotes on
T20624 1436-1441 NN denotes c-Jun
T20623 1433-1435 IN denotes of
T20622 1417-1432 NN denotes phosphorylation
T20621 1412-1416 FW denotes e.g.
T20620 1411-1412 -LRB- denotes (
T20619 1401-1410 JJ denotes redundant
T20618 1394-1400 RB denotes either
T20617 1391-1393 VB denotes be
T20616 1387-1390 MD denotes may
T20615 1383-1386 CC denotes but
T20614 1381-1382 , denotes ,
T20613 1371-1381 NN denotes activation
T20612 1363-1370 NN denotes pathway
T20611 1360-1362 IN denotes of
T20610 1353-1359 NN denotes marker
T20609 1346-1352 JJ denotes useful
T20608 1344-1345 DT denotes a
T20607 1341-1343 IN denotes as
T20606 1335-1340 VB denotes serve
T20605 1331-1334 MD denotes may
T20604 1322-1330 NN denotes activity
T20603 1318-1321 NNP denotes JNK
T20602 1312-1317 IN denotes while
T20601 1310-1311 , denotes ,
T20600 1299-1310 NN denotes necroptosis
T20599 1295-1298 IN denotes for
T20598 1286-1294 JJ denotes critical
T20597 1283-1285 VBZ denotes is
T20596 1277-1282 NNP denotes c-Jun
T20595 1272-1276 WDT denotes that
T20582 1205-1206 . denotes .
T20581 1204-1205 -RRB- denotes )
T20580 1203-1204 NN denotes F
T20579 1202-1203 , denotes ,
T20578 1200-1202 NNP denotes 6E
T20577 1195-1199 NNP denotes Fig.
T20576 1194-1195 -LRB- denotes (
T20575 1179-1193 NNP denotes mTOR-dependent
T20574 1175-1178 CC denotes and
T20573 1171-1174 NNP denotes Akt
T20572 1166-1170 DT denotes both
T20571 1162-1165 VBD denotes was
T20570 1156-1161 WDT denotes which
T20569 1154-1155 , denotes ,
T20568 1150-1154 NNP denotes TNFα
T20567 1147-1149 CC denotes or
T20566 1138-1146 NNP denotes zVAD.fmk
T20565 1133-1137 IN denotes with
T20564 1127-1132 NNS denotes cells
T20563 1122-1126 CD denotes L929
T20562 1119-1121 IN denotes of
T20561 1109-1118 NN denotes treatment
T20560 1103-1108 IN denotes after
T20559 1097-1102 JJ denotes c-Jun
T20558 1094-1096 IN denotes of
T20557 1088-1093 NN denotes level
T20556 1080-1087 NN denotes protein
T20555 1076-1079 DT denotes the
T20554 1073-1075 IN denotes in
T20553 1064-1072 NN denotes increase
T20552 1056-1063 JJ denotes overall
T20551 1053-1055 DT denotes an
T20550 1044-1052 VBD denotes observed
T20549 1041-1043 PRP denotes we
T20548 1036-1040 IN denotes that
T20547 1031-1035 VB denotes note
T20546 1028-1030 TO denotes to
T20545 1018-1027 JJ denotes important
T20544 1013-1017 RB denotes also
T20543 1010-1012 VBZ denotes is
T20542 1007-1009 PRP denotes It
T20541 1005-1006 . denotes .
T20540 1002-1005 NNP denotes Akt
T20539 999-1001 IN denotes of
T20538 988-998 NN denotes activation
T20537 980-987 VBN denotes delayed
T20536 976-979 DT denotes the
T20535 973-975 TO denotes to
T20534 961-972 VBZ denotes contributes
T20533 956-960 WDT denotes that
T20532 951-955 NN denotes loop
T20531 942-950 NN denotes feedback
T20530 940-941 DT denotes a
T20529 933-939 VB denotes create
T20528 929-932 MD denotes may
T20527 927-928 , denotes ,
T20526 922-927 JJ denotes c-Jun
T20525 919-921 IN denotes on
T20524 909-918 JJ denotes dependent
T20523 907-908 , denotes ,
T20522 897-907 NN denotes production
T20521 892-896 NN denotes TNFα
T20520 882-891 NN denotes autocrine
T20519 880-881 , denotes ,
T20518 876-880 RB denotes Thus
T20517 874-875 . denotes .
T20516 863-874 NN denotes necroptosis
T20515 860-862 IN denotes of
T20514 850-859 NN denotes induction
T20513 846-849 DT denotes the
T20512 840-845 IN denotes after
T20511 832-839 VBN denotes reduced
T20510 828-831 VBD denotes was
T20509 812-827 NN denotes phosphorylation
T20508 805-811 NNP denotes Thr308
T20507 803-804 , denotes ,
T20506 799-803 NN denotes case
T20505 794-798 DT denotes this
T20504 791-793 IN denotes in
T20503 789-790 , denotes ,
T20502 782-789 RB denotes Notably
T20501 780-781 . denotes .
T20500 779-780 -RRB- denotes )
T20499 778-779 NNP denotes J
T20498 773-777 CD denotes S10H
T20497 771-772 . denotes .
T20496 768-771 NNP denotes Fig
T20495 767-768 -LRB- denotes (
T20494 757-766 VBN denotes knockdown
T20493 751-756 NN denotes siRNA
T20492 745-750 JJ denotes c-Jun
T20491 739-744 VBG denotes using
T20490 727-738 NNS denotes conclusions
T20489 721-726 DT denotes these
T20488 711-720 VBD denotes confirmed
T20487 708-710 PRP denotes we
T20486 704-707 CC denotes and
T20485 702-703 NNP denotes ]
T20484 700-702 CD denotes 15
T20483 699-700 NNP denotes [
T20482 697-698 , denotes ,
T20481 696-697 NNP denotes ]
T20480 694-696 CD denotes 14
T20479 693-694 NNP denotes [
T20478 691-692 , denotes ,
T20477 690-691 NNP denotes ]
T20476 688-690 CD denotes 13
T20475 687-688 NNP denotes [
T20474 677-686 NN denotes synthesis
T20473 672-676 NNP denotes TNFα
T20472 662-671 NN denotes autocrine
T20471 658-661 CC denotes and
T20470 646-657 NN denotes necroptosis
T20469 643-645 IN denotes in
T20468 637-642 NN denotes c-Jun
T20467 633-636 IN denotes for
T20466 628-632 NN denotes role
T20465 619-627 JJ denotes critical
T20464 617-618 DT denotes a
T20463 607-616 VBD denotes suggested
T20462 602-606 RB denotes also
T20461 594-601 NNS denotes reports
T20460 585-593 JJ denotes Previous
T20459 583-584 . denotes .
T20458 573-583 NN denotes inhibition
T20457 569-572 NNP denotes JNK
T20456 564-568 IN denotes than
T20455 557-563 RB denotes rather
T20454 555-556 , denotes ,
T20453 547-555 NN denotes molecule
T20452 542-546 DT denotes this
T20451 539-541 IN denotes of
T20450 531-538 NNS denotes effects
T20449 520-530 JJ denotes off-target
T20448 512-519 VB denotes reflect
T20447 506-511 MD denotes could
T20446 504-505 -RRB- denotes )
T20445 503-504 LS denotes 2
T20444 498-502 FW denotes Fig.
T20443 497-498 -LRB- denotes (
T20442 486-496 NN denotes protection
T20441 477-485 CD denotes SP600125
T20440 472-476 IN denotes with
T20439 467-471 NNS denotes data
T20438 459-466 JJR denotes earlier
T20437 454-458 IN denotes that
T20436 443-453 VBG denotes suggesting
T20435 441-442 , denotes ,
T20434 440-441 -RRB- denotes )
T20433 439-440 NNP denotes G
T20432 438-439 , denotes ,
T20431 437-438 NN denotes F
T20430 436-437 , denotes ,
T20429 435-436 NNP denotes D
T20428 434-435 , denotes ,
T20427 430-434 CD denotes S10C
T20426 428-429 . denotes .
T20425 425-428 NNP denotes Fig
T20424 424-425 -LRB- denotes (
T20423 418-423 NN denotes death
T20422 413-417 NN denotes cell
T20421 410-412 CC denotes or
T20420 399-409 NN denotes production
T20419 394-398 JJ denotes TNFα
T20418 391-393 IN denotes in
T20417 381-390 NN denotes reduction
T20416 379-380 DT denotes a
T20415 376-378 TO denotes to
T20414 371-375 VBP denotes lead
T20413 369-370 , denotes ,
T20412 362-369 RB denotes however
T20411 360-361 , denotes ,
T20410 357-360 RB denotes not
T20409 353-356 VBD denotes did
T20408 350-352 PRP denotes It
T20407 348-349 . denotes .
T20406 343-348 NN denotes model
T20405 339-342 PRP$ denotes our
T20403 325-333 VBG denotes agreeing
T20402 323-324 , denotes ,
T20401 322-323 -RRB- denotes )
T20400 321-322 NNP denotes E
T20399 320-321 , denotes ,
T20398 316-320 CD denotes S10B
T20397 314-315 . denotes .
T20396 311-314 NNP denotes Fig
T20395 310-311 -LRB- denotes (
T20394 304-309 NNP denotes Ser63
T20393 301-303 IN denotes at
T20392 295-300 NN denotes c-Jun
T20391 292-294 IN denotes of
T20390 276-291 NN denotes phosphorylation
T20389 272-275 DT denotes the
T20388 261-271 VBG denotes inhibiting
T20387 255-260 IN denotes while
T20386 248-254 NNP denotes Thr308
T20385 245-247 IN denotes on
T20384 241-244 NNP denotes Akt
T20383 238-240 IN denotes of
T20382 222-237 NN denotes phosphorylation
T20381 214-221 VBN denotes allowed
T20380 207-213 NN denotes JNK1/2
T20379 204-206 IN denotes of
T20378 194-203 NN denotes knockdown
T20377 191-193 CC denotes or
T20376 180-190 NN denotes inhibition
T20375 171-179 JJ denotes specific
T20374 169-170 , denotes ,
T20373 161-169 VBN denotes expected
T20372 158-160 IN denotes As
T20371 156-157 . denotes .
T20370 155-156 -RRB- denotes )
T20369 154-155 NNP denotes G
T20368 149-153 CD denotes S10B
T20367 147-148 . denotes .
T20594 1261-1271 NN denotes conclusion
T20593 1251-1260 JJ denotes important
T20592 1247-1250 CC denotes but
T20591 1245-1246 , denotes ,
T20590 1235-1245 JJ denotes unexpected
T20589 1232-1234 DT denotes an
T20588 1229-1231 TO denotes to
T20587 1226-1228 PRP denotes us
T20586 1222-1225 VBD denotes led
T20585 1217-1221 NNS denotes data
T20584 1213-1216 JJ denotes new
T20583 1207-1212 DT denotes These
T20366 144-147 NNP denotes Fig
T20365 143-144 -LRB- denotes (
T20364 138-142 NNP denotes JNK2
T20363 134-137 CC denotes and
T20362 129-133 NNP denotes JNK1
T20361 121-128 IN denotes against
T20360 114-120 NNS denotes siRNAs
T20359 110-113 CC denotes and
T20358 108-109 , denotes ,
T20357 107-108 NNP denotes ]
T20356 105-107 CD denotes 43
T20355 104-105 NNP denotes [
T20354 99-103 NNP denotes VIII
T20353 89-98 NN denotes inhibitor
T20352 85-88 NNP denotes JNK
T20351 83-84 , denotes ,
T20350 74-83 NN denotes inhibitor
T20349 70-73 NNP denotes JNK
T20348 61-69 JJ denotes specific
T20347 56-60 RBR denotes more
T20346 54-55 DT denotes a
T20345 51-53 TO denotes to
T20344 42-50 VBD denotes switched
T20343 39-41 PRP denotes we
T20342 37-38 , denotes ,
T20341 34-37 NNP denotes JNK
T20340 31-33 IN denotes of
T20339 26-30 NN denotes role
T20338 22-25 DT denotes the
T20337 14-21 VB denotes examine
T20336 11-13 TO denotes to
T20335 9-10 , denotes ,
T20334 0-9 RB denotes Therefore
R13585 T20334 T20344 advmod Therefore,switched
R13586 T20335 T20344 punct ",",switched
R13587 T20336 T20337 aux to,examine
R13588 T20337 T20344 advcl examine,switched
R13589 T20338 T20339 det the,role
R13590 T20339 T20337 dobj role,examine
R13591 T20340 T20339 prep of,role
R13592 T20341 T20340 pobj JNK,of
R13593 T20342 T20344 punct ",",switched
R13594 T20343 T20344 nsubj we,switched
R13595 T20344 T20344 ROOT switched,switched
R13596 T20345 T20344 prep to,switched
R13597 T20346 T20350 det a,inhibitor
R13598 T20347 T20348 advmod more,specific
R13599 T20348 T20350 amod specific,inhibitor
R13600 T20349 T20350 compound JNK,inhibitor
R13601 T20350 T20345 pobj inhibitor,to
R13602 T20351 T20344 punct ",",switched
R13603 T20352 T20353 compound JNK,inhibitor
R13604 T20353 T20344 npadvmod inhibitor,switched
R13605 T20354 T20355 compound VIII,[
R13606 T20355 T20353 appos [,inhibitor
R13607 T20356 T20357 nummod 43,]
R13608 T20357 T20353 conj ],inhibitor
R13609 T20358 T20357 punct ",",]
R13610 T20359 T20357 cc and,]
R13611 T20360 T20357 conj siRNAs,]
R13612 T20361 T20360 prep against,siRNAs
R13613 T20362 T20361 pobj JNK1,against
R13614 T20363 T20362 cc and,JNK1
R13615 T20364 T20362 conj JNK2,JNK1
R13616 T20365 T20366 punct (,Fig
R13617 T20366 T20364 appos Fig,JNK2
R13618 T20367 T20344 punct .,switched
R13619 T20368 T20369 nummod S10B,G
R13620 T20369 T20369 ROOT G,G
R13621 T20370 T20369 punct ),G
R13622 T20371 T20369 punct .,G
R13623 T20372 T20373 mark As,expected
R13624 T20373 T20381 advcl expected,allowed
R13625 T20374 T20373 punct ",",expected
R13626 T20375 T20376 amod specific,inhibition
R13627 T20376 T20381 nsubj inhibition,allowed
R13628 T20377 T20376 cc or,inhibition
R13629 T20378 T20376 conj knockdown,inhibition
R13630 T20379 T20376 prep of,inhibition
R13631 T20380 T20379 pobj JNK1/2,of
R13632 T20381 T20381 ROOT allowed,allowed
R13633 T20382 T20381 dobj phosphorylation,allowed
R13634 T20383 T20382 prep of,phosphorylation
R13635 T20384 T20383 pobj Akt,of
R13636 T20385 T20382 prep on,phosphorylation
R13637 T20386 T20385 pobj Thr308,on
R13638 T20387 T20388 mark while,inhibiting
R13639 T20388 T20381 advcl inhibiting,allowed
R13640 T20389 T20390 det the,phosphorylation
R13641 T20390 T20388 dobj phosphorylation,inhibiting
R13642 T20391 T20390 prep of,phosphorylation
R13643 T20392 T20391 pobj c-Jun,of
R13644 T20393 T20388 prep at,inhibiting
R13645 T20394 T20393 pobj Ser63,at
R13646 T20395 T20396 punct (,Fig
R13647 T20396 T20394 appos Fig,Ser63
R13648 T20397 T20381 punct .,allowed
R13649 T20398 T20400 nummod S10B,E
R13650 T20399 T20400 punct ",",E
R13651 T20400 T20400 ROOT E,E
R13652 T20401 T20400 punct ),E
R13653 T20402 T20400 punct ",",E
R13654 T20403 T20400 acl agreeing,E
R13655 T20404 T20403 prep with,agreeing
R13656 T20405 T20406 poss our,model
R13657 T20406 T20404 pobj model,with
R13658 T20407 T20400 punct .,E
R13659 T20408 T20414 nsubj It,lead
R13660 T20409 T20414 aux did,lead
R13661 T20410 T20409 neg not,did
R13662 T20411 T20414 punct ",",lead
R13663 T20412 T20414 advmod however,lead
R13664 T20413 T20414 punct ",",lead
R13665 T20414 T20414 ROOT lead,lead
R13666 T20415 T20414 prep to,lead
R13667 T20416 T20417 det a,reduction
R13668 T20417 T20415 pobj reduction,to
R13669 T20418 T20417 prep in,reduction
R13670 T20419 T20420 amod TNFα,production
R13671 T20420 T20418 pobj production,in
R13672 T20421 T20420 cc or,production
R13673 T20422 T20423 compound cell,death
R13674 T20423 T20420 conj death,production
R13675 T20424 T20420 punct (,production
R13676 T20425 T20417 appos Fig,reduction
R13677 T20426 T20414 punct .,lead
R13678 T20427 T20427 ROOT S10C,S10C
R13679 T20428 T20427 punct ",",S10C
R13680 T20429 T20427 appos D,S10C
R13681 T20430 T20429 punct ",",D
R13682 T20431 T20429 appos F,D
R13683 T20432 T20429 punct ",",D
R13684 T20433 T20429 conj G,D
R13685 T20434 T20429 punct ),D
R13686 T20435 T20427 punct ",",S10C
R13687 T20436 T20427 acl suggesting,S10C
R13688 T20437 T20448 mark that,reflect
R13689 T20438 T20439 amod earlier,data
R13690 T20439 T20448 nsubj data,reflect
R13691 T20440 T20439 prep with,data
R13692 T20441 T20442 nummod SP600125,protection
R13693 T20442 T20440 pobj protection,with
R13694 T20443 T20442 punct (,protection
R13695 T20444 T20442 appos Fig.,protection
R13696 T20445 T20444 appos 2,Fig.
R13697 T20446 T20442 punct ),protection
R13698 T20447 T20448 aux could,reflect
R13699 T20448 T20436 ccomp reflect,suggesting
R13700 T20449 T20450 amod off-target,effects
R13701 T20450 T20448 dobj effects,reflect
R13702 T20451 T20450 prep of,effects
R13703 T20452 T20453 det this,molecule
R13704 T20453 T20451 pobj molecule,of
R13705 T20454 T20450 punct ",",effects
R13706 T20455 T20456 advmod rather,than
R13707 T20456 T20450 cc than,effects
R13708 T20457 T20458 compound JNK,inhibition
R13709 T20458 T20450 conj inhibition,effects
R13710 T20459 T20427 punct .,S10C
R13711 T20460 T20461 amod Previous,reports
R13712 T20461 T20463 nsubj reports,suggested
R13713 T20462 T20463 advmod also,suggested
R13714 T20463 T20463 ROOT suggested,suggested
R13715 T20464 T20466 det a,role
R13716 T20465 T20466 amod critical,role
R13717 T20466 T20463 dobj role,suggested
R13718 T20467 T20466 prep for,role
R13719 T20468 T20467 pobj c-Jun,for
R13720 T20469 T20468 prep in,c-Jun
R13721 T20470 T20469 pobj necroptosis,in
R13722 T20471 T20470 cc and,necroptosis
R13723 T20472 T20473 compound autocrine,TNFα
R13724 T20473 T20474 compound TNFα,synthesis
R13725 T20474 T20466 conj synthesis,role
R13726 T20475 T20477 nmod [,]
R13727 T20476 T20477 nummod 13,]
R13728 T20477 T20474 appos ],synthesis
R13729 T20478 T20477 punct ",",]
R13730 T20479 T20477 conj [,]
R13731 T20480 T20481 nummod 14,]
R13732 T20481 T20477 conj ],]
R13733 T20482 T20481 punct ",",]
R13734 T20483 T20481 conj [,]
R13735 T20484 T20485 nummod 15,]
R13736 T20485 T20481 conj ],]
R13737 T20486 T20463 cc and,suggested
R13738 T20487 T20488 nsubj we,confirmed
R13739 T20488 T20463 conj confirmed,suggested
R13740 T20489 T20490 det these,conclusions
R13741 T20490 T20488 dobj conclusions,confirmed
R13742 T20491 T20488 advcl using,confirmed
R13743 T20492 T20493 amod c-Jun,siRNA
R13744 T20493 T20491 dobj siRNA,using
R13745 T20494 T20493 acl knockdown,siRNA
R13746 T20495 T20496 punct (,Fig
R13747 T20496 T20494 appos Fig,knockdown
R13748 T20497 T20488 punct .,confirmed
R13749 T20498 T20499 nummod S10H,J
R13750 T20499 T20499 ROOT J,J
R13751 T20500 T20499 punct ),J
R13752 T20501 T20499 punct .,J
R13753 T20502 T20511 advmod Notably,reduced
R13754 T20503 T20511 punct ",",reduced
R13755 T20504 T20511 prep in,reduced
R13756 T20505 T20506 det this,case
R13757 T20506 T20504 pobj case,in
R13758 T20507 T20511 punct ",",reduced
R13759 T20508 T20509 compound Thr308,phosphorylation
R13760 T20509 T20511 nsubjpass phosphorylation,reduced
R13761 T20510 T20511 auxpass was,reduced
R13762 T20511 T20511 ROOT reduced,reduced
R13763 T20512 T20511 prep after,reduced
R13764 T20513 T20514 det the,induction
R13765 T20514 T20512 pobj induction,after
R13766 T20515 T20514 prep of,induction
R13767 T20516 T20515 pobj necroptosis,of
R13768 T20517 T20511 punct .,reduced
R13769 T20518 T20529 advmod Thus,create
R13770 T20519 T20529 punct ",",create
R13771 T20520 T20522 nmod autocrine,production
R13772 T20521 T20522 compound TNFα,production
R13773 T20522 T20529 nsubj production,create
R13774 T20523 T20522 punct ",",production
R13775 T20524 T20522 amod dependent,production
R13776 T20525 T20524 prep on,dependent
R13777 T20526 T20525 pobj c-Jun,on
R13778 T20527 T20529 punct ",",create
R13779 T20528 T20529 aux may,create
R13780 T20529 T20529 ROOT create,create
R13781 T20530 T20532 det a,loop
R13782 T20531 T20532 compound feedback,loop
R13783 T20532 T20529 dobj loop,create
R13784 T20533 T20534 nsubj that,contributes
R13785 T20534 T20532 relcl contributes,loop
R13786 T20535 T20534 prep to,contributes
R13787 T20536 T20538 det the,activation
R13788 T20537 T20538 amod delayed,activation
R13789 T20538 T20535 pobj activation,to
R13790 T20539 T20538 prep of,activation
R13791 T20540 T20539 pobj Akt,of
R13792 T20541 T20529 punct .,create
R13793 T20542 T20543 nsubj It,is
R13794 T20543 T20543 ROOT is,is
R13795 T20544 T20543 advmod also,is
R13796 T20545 T20543 acomp important,is
R13797 T20546 T20547 aux to,note
R13798 T20547 T20543 xcomp note,is
R13799 T20548 T20550 mark that,observed
R13800 T20549 T20550 nsubj we,observed
R13801 T20550 T20547 ccomp observed,note
R13802 T20551 T20553 det an,increase
R13803 T20552 T20553 amod overall,increase
R13804 T20553 T20550 dobj increase,observed
R13805 T20554 T20553 prep in,increase
R13806 T20555 T20557 det the,level
R13807 T20556 T20557 compound protein,level
R13808 T20557 T20554 pobj level,in
R13809 T20558 T20557 prep of,level
R13810 T20559 T20558 pobj c-Jun,of
R13811 T20560 T20553 prep after,increase
R13812 T20561 T20560 pobj treatment,after
R13813 T20562 T20561 prep of,treatment
R13814 T20563 T20564 nummod L929,cells
R13815 T20564 T20562 pobj cells,of
R13816 T20565 T20553 prep with,increase
R13817 T20566 T20565 pobj zVAD.fmk,with
R13818 T20567 T20566 cc or,zVAD.fmk
R13819 T20568 T20566 conj TNFα,zVAD.fmk
R13820 T20569 T20566 punct ",",zVAD.fmk
R13821 T20570 T20571 nsubj which,was
R13822 T20571 T20553 relcl was,increase
R13823 T20572 T20573 det both,Akt
R13824 T20573 T20571 attr Akt,was
R13825 T20574 T20573 cc and,Akt
R13826 T20575 T20573 conj mTOR-dependent,Akt
R13827 T20576 T20578 punct (,6E
R13828 T20577 T20578 compound Fig.,6E
R13829 T20578 T20573 conj 6E,Akt
R13830 T20579 T20578 punct ",",6E
R13831 T20580 T20578 appos F,6E
R13832 T20581 T20578 punct ),6E
R13833 T20582 T20543 punct .,is
R13834 T20583 T20585 det These,data
R13835 T20584 T20585 amod new,data
R13836 T20585 T20586 nsubj data,led
R13837 T20586 T20586 ROOT led,led
R13838 T20587 T20586 dobj us,led
R13839 T20588 T20586 prep to,led
R13840 T20589 T20594 det an,conclusion
R13841 T20590 T20594 amod unexpected,conclusion
R13842 T20591 T20590 punct ",",unexpected
R13843 T20592 T20590 cc but,unexpected
R13844 T20593 T20590 conj important,unexpected
R13845 T20594 T20588 pobj conclusion,to
R13846 T20595 T20597 mark that,is
R13847 T20596 T20597 nsubj c-Jun,is
R13848 T20597 T20594 acl is,conclusion
R13849 T20598 T20597 acomp critical,is
R13850 T20599 T20598 prep for,critical
R13851 T20600 T20599 pobj necroptosis,for
R13852 T20601 T20586 punct ",",led
R13853 T20602 T20606 mark while,serve
R13854 T20603 T20604 compound JNK,activity
R13855 T20604 T20606 nsubj activity,serve
R13856 T20605 T20606 aux may,serve
R13857 T20606 T20586 advcl serve,led
R13858 T20607 T20606 prep as,serve
R13859 T20608 T20610 det a,marker
R13860 T20609 T20610 amod useful,marker
R13861 T20610 T20607 pobj marker,as
R13862 T20611 T20610 prep of,marker
R13863 T20612 T20613 compound pathway,activation
R13864 T20613 T20611 pobj activation,of
R13865 T20614 T20586 punct ",",led
R13866 T20615 T20586 cc but,led
R13867 T20616 T20617 aux may,be
R13868 T20617 T20586 conj be,led
R13869 T20618 T20619 advmod either,redundant
R13870 T20619 T20617 acomp redundant,be
R13871 T20620 T20622 punct (,phosphorylation
R13872 T20621 T20622 compound e.g.,phosphorylation
R13873 T20622 T20632 nsubj phosphorylation,occur
R13874 T20623 T20622 prep of,phosphorylation
R13875 T20624 T20623 pobj c-Jun,of
R13876 T20625 T20622 prep on,phosphorylation
R13877 T20626 T20627 det a,site
R13878 T20627 T20625 pobj site,on
R13879 T20628 T20627 amod other,site
R13880 T20629 T20632 mark than,occur
R13881 T20630 T20632 nsubj Ser63,occur
R13882 T20631 T20632 aux may,occur
R13883 T20632 T20617 advcl occur,be
R13884 T20633 T20632 dobj [,occur
R13885 T20634 T20635 nummod 44,]
R13886 T20635 T20633 nmod ],[
R13887 T20636 T20633 punct ),[
R13888 T20637 T20633 cc or,[
R13889 T20638 T20633 conj dispensable,[
R13890 T20639 T20638 advmod functionally,dispensable
R13891 T20640 T20586 punct .,led
R13892 T20641 T20645 prep In,need
R13893 T20642 T20641 pobj addition,In
R13894 T20643 T20645 punct ",",need
R13895 T20644 T20645 nsubj researchers,need
R13896 T20645 T20645 ROOT need,need
R13897 T20646 T20647 aux to,use
R13898 T20647 T20645 xcomp use,need
R13899 T20648 T20647 dobj caution,use
R13900 T20649 T20650 advmod when,using
R13901 T20650 T20647 advcl using,use
R13902 T20651 T20652 advmod SP600125,due
R13903 T20652 T20650 dobj due,using
R13904 T20653 T20652 pcomp to,due
R13905 T20654 T20656 amod potantial,effects
R13906 T20655 T20656 amod off-target,effects
R13907 T20656 T20653 pobj effects,to
R13908 T20657 T20645 punct .,need

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T19655 1417-1432 Phosphorylation denotes phosphorylation
T19654 1436-1441 Protein denotes c-Jun
T19653 1318-1321 Protein denotes JNK
T19652 1277-1282 Protein denotes c-Jun
T19651 1064-1072 Positive_regulation denotes increase
T19650 1064-1072 Positive_regulation denotes increase
T19649 1179-1183 Protein denotes mTOR
T19648 1171-1174 Protein denotes Akt
T19647 1150-1154 Protein denotes TNFα
T19646 1138-1146 Protein denotes zVAD.fmk
T19645 1097-1102 Protein denotes c-Jun
T19644 988-998 Positive_regulation denotes activation
T19643 909-918 Positive_regulation denotes dependent
T19642 897-907 Gene_expression denotes production
T19641 1002-1005 Protein denotes Akt
T19640 922-927 Protein denotes c-Jun
T19639 882-896 Protein denotes autocrine TNFα
T19638 628-632 Regulation denotes role
T19637 757-766 Negative_regulation denotes knockdown
T19636 677-686 Gene_expression denotes synthesis
T19635 745-756 Protein denotes c-Jun siRNA
T19634 662-676 Protein denotes autocrine TNFα
T19633 637-642 Protein denotes c-Jun
T19632 381-390 Negative_regulation denotes reduction
T19631 399-409 Gene_expression denotes production
T19630 569-572 Protein denotes JNK
T19629 394-398 Protein denotes TNFα
T19628 261-271 Negative_regulation denotes inhibiting
T19627 276-291 Phosphorylation denotes phosphorylation
T19626 222-237 Phosphorylation denotes phosphorylation
T19625 180-190 Negative_regulation denotes inhibition
T19624 295-300 Protein denotes c-Jun
T19623 241-244 Protein denotes Akt
T19622 207-211 Protein denotes JNK1
T19621 74-83 Negative_regulation denotes inhibitor
T19620 149-155 Protein denotes S10B–G
T19619 144-147 Protein denotes Fig
T19618 138-142 Protein denotes JNK2
T19617 129-133 Protein denotes JNK1
T19616 85-88 Protein denotes JNK
T19615 70-73 Protein denotes JNK
T19614 34-37 Protein denotes JNK
R13056 T19642 T19643 themeOf production,dependent
R13057 T19645 T19650 themeOf c-Jun,increase
R13058 T19645 T19651 themeOf c-Jun,increase
R13059 T19647 T19651 causeOf TNFα,increase
R13060 T19654 T19655 themeOf c-Jun,phosphorylation
R13042 T19615 T19621 themeOf JNK,inhibitor
R13043 T19622 T19625 themeOf JNK1,inhibition
R13044 T19623 T19626 themeOf Akt,phosphorylation
R13045 T19624 T19627 themeOf c-Jun,phosphorylation
R13046 T19627 T19628 themeOf phosphorylation,inhibiting
R13047 T19629 T19631 themeOf TNFα,production
R13048 T19631 T19632 themeOf production,reduction
R13049 T19633 T19638 causeOf c-Jun,role
R13050 T19634 T19636 themeOf autocrine TNFα,synthesis
R13051 T19635 T19637 themeOf c-Jun siRNA,knockdown
R13052 T19636 T19638 themeOf synthesis,role
R13053 T19639 T19642 themeOf autocrine TNFα,production
R13054 T19640 T19643 causeOf c-Jun,dependent
R13055 T19641 T19644 themeOf Akt,activation

test3

Id Subject Object Predicate Lexical cue
T18311 1436-1441 Protein denotes c-Jun
T18310 1417-1432 Phosphorylation denotes phosphorylation
T18309 1277-1282 Protein denotes c-Jun
T18308 1184-1193 Regulation denotes dependent
T18307 1150-1154 Protein denotes TNFα
T18306 1097-1102 Protein denotes c-Jun
T18305 1064-1072 Positive_regulation denotes increase
T18304 988-998 Positive_regulation denotes activation
T18303 961-972 Positive_regulation denotes contributes
T18302 922-927 Protein denotes c-Jun
T18301 909-918 Regulation denotes dependent
T18300 897-907 Gene_expression denotes production
T18299 892-896 Protein denotes TNFα
T18298 882-891 Regulation denotes autocrine
T18297 832-839 Negative_regulation denotes reduced
T18296 812-827 Phosphorylation denotes phosphorylation
T18295 757-766 Negative_regulation denotes knockdown
T18294 745-750 Protein denotes c-Jun
T18293 677-686 Gene_expression denotes synthesis
T18292 672-676 Protein denotes TNFα
T18291 637-642 Protein denotes c-Jun
T18290 399-409 Gene_expression denotes production
T18289 394-398 Protein denotes TNFα
T18288 381-390 Negative_regulation denotes reduction
T18287 295-300 Protein denotes c-Jun
T18286 276-291 Phosphorylation denotes phosphorylation
T18285 261-271 Negative_regulation denotes inhibiting
T18284 222-237 Phosphorylation denotes phosphorylation
T18283 212-213 Protein denotes 2
T18282 207-211 Protein denotes JNK1
T18281 194-203 Negative_regulation denotes knockdown
T18280 138-142 Protein denotes JNK2
T18279 129-133 Protein denotes JNK1
T18245 1436-1441 Protein denotes c-Jun
T18244 1277-1282 Protein denotes c-Jun
T18243 1150-1154 Protein denotes TNFα
T18242 1097-1102 Protein denotes c-Jun
T18241 922-927 Protein denotes c-Jun
T18240 892-896 Protein denotes TNFα
T18239 745-750 Protein denotes c-Jun
T18238 672-676 Protein denotes TNFα
T18237 637-642 Protein denotes c-Jun
T18236 394-398 Protein denotes TNFα
T18235 295-300 Protein denotes c-Jun
T18234 212-213 Protein denotes 2
T18233 207-211 Protein denotes JNK1
T18232 138-142 Protein denotes JNK2
T18231 129-133 Protein denotes JNK1
R12116 T18282 T18281 themeOf JNK1,knockdown
R12117 T18283 T18281 themeOf 2,knockdown
R12118 T18286 T18285 themeOf phosphorylation,inhibiting
R12119 T18287 T18286 themeOf c-Jun,phosphorylation
R12120 T18289 T18290 themeOf TNFα,production
R12121 T18290 T18288 themeOf production,reduction
R12122 T18292 T18293 themeOf TNFα,synthesis
R12123 T18294 T18295 themeOf c-Jun,knockdown
R12124 T18296 T18297 themeOf phosphorylation,reduced
R12125 T18298 T18301 themeOf autocrine,dependent
R12126 T18299 T18300 themeOf TNFα,production
R12127 T18300 T18298 themeOf production,autocrine
R12128 T18300 T18301 themeOf production,dependent
R12129 T18302 T18301 causeOf c-Jun,dependent
R12130 T18306 T18305 themeOf c-Jun,increase
R12131 T18307 T18305 themeOf TNFα,increase
R12132 T18311 T18310 themeOf c-Jun,phosphorylation