PMC:3585731 / 31557-31793 JSONTXT

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{"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T13862","span":{"begin":150,"end":157},"obj":"Protein"},{"id":"T13861","span":{"begin":96,"end":100},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Under serum free conditions all zVAD.fmk-induced downstream events (cell death, JNK activation, TNFα production) were dependent on the over expressed Myr-Akt. This allowed us to examine the effects of other Akt mutations on necroptosis."}

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T15044","span":{"begin":207,"end":210},"obj":"http://www.uniprot.org/uniprot/P31751"},{"id":"T15043","span":{"begin":154,"end":157},"obj":"http://www.uniprot.org/uniprot/P31751"},{"id":"T15009","span":{"begin":207,"end":210},"obj":"http://www.uniprot.org/uniprot/P31749"},{"id":"T15008","span":{"begin":154,"end":157},"obj":"http://www.uniprot.org/uniprot/P31749"},{"id":"T15096","span":{"begin":96,"end":100},"obj":"http://www.uniprot.org/uniprot/P01375"},{"id":"T15079","span":{"begin":207,"end":210},"obj":"http://www.uniprot.org/uniprot/Q9Y243"},{"id":"T15078","span":{"begin":154,"end":157},"obj":"http://www.uniprot.org/uniprot/Q9Y243"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"Under serum free conditions all zVAD.fmk-induced downstream events (cell death, JNK activation, TNFα production) were dependent on the over expressed Myr-Akt. This allowed us to examine the effects of other Akt mutations on necroptosis."}

{"project":"UBERON-AE","denotations":[{"id":"T13694","span":{"begin":6,"end":11},"obj":"http://purl.obolibrary.org/obo/UBERON_0001977"}],"text":"Under serum free conditions all zVAD.fmk-induced downstream events (cell death, JNK activation, TNFα production) were dependent on the over expressed Myr-Akt. This allowed us to examine the effects of other Akt mutations on necroptosis."}

{"project":"GO-BP","denotations":[{"id":"T13939","span":{"begin":80,"end":83},"obj":"http://purl.obolibrary.org/obo/GO_0004705"},{"id":"T13922","span":{"begin":73,"end":78},"obj":"http://purl.obolibrary.org/obo/GO_0016265"},{"id":"T13916","span":{"begin":68,"end":78},"obj":"http://purl.obolibrary.org/obo/GO_0008219"},{"id":"T13901","span":{"begin":224,"end":235},"obj":"http://purl.obolibrary.org/obo/GO_0097528"},{"id":"T13887","span":{"begin":224,"end":235},"obj":"http://purl.obolibrary.org/obo/GO_0070266"}],"text":"Under serum free conditions all zVAD.fmk-induced downstream events (cell death, JNK activation, TNFα production) were dependent on the over expressed Myr-Akt. This allowed us to examine the effects of other Akt mutations on necroptosis."}

{"project":"GO-MF","denotations":[{"id":"T13957","span":{"begin":80,"end":83},"obj":"http://purl.obolibrary.org/obo/GO_0004705"}],"text":"Under serum free conditions all zVAD.fmk-induced downstream events (cell death, JNK activation, TNFα production) were dependent on the over expressed Myr-Akt. This allowed us to examine the effects of other Akt mutations on necroptosis."}

{"project":"sentences","denotations":[{"id":"T13710","span":{"begin":0,"end":236},"obj":"Sentence"},{"id":"T198","span":{"begin":0,"end":158},"obj":"Sentence"},{"id":"T199","span":{"begin":159,"end":236},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Under serum free conditions all zVAD.fmk-induced downstream events (cell death, JNK activation, TNFα production) were dependent on the over expressed Myr-Akt. This allowed us to examine the effects of other Akt mutations on necroptosis."}

{"project":"simple1","denotations":[{"id":"T14045","span":{"begin":150,"end":157},"obj":"Protein"},{"id":"T14044","span":{"begin":96,"end":100},"obj":"Protein"}],"text":"Under serum free conditions all zVAD.fmk-induced downstream events (cell death, JNK activation, TNFα production) were dependent on the over expressed Myr-Akt. This allowed us to examine the effects of other Akt mutations on necroptosis."}

{"project":"BioNLP16_DUT","denotations":[{"id":"T14972","span":{"begin":140,"end":149},"obj":"Gene_expression"},{"id":"T14971","span":{"begin":101,"end":111},"obj":"Gene_expression"},{"id":"T14941","span":{"begin":150,"end":157},"obj":"Protein"},{"id":"T14940","span":{"begin":96,"end":100},"obj":"Protein"}],"relations":[{"id":"R9929","pred":"themeOf","subj":"T14940","obj":"T14971"},{"id":"R9930","pred":"themeOf","subj":"T14941","obj":"T14972"}],"text":"Under serum free conditions all zVAD.fmk-induced downstream events (cell death, JNK activation, TNFα production) were dependent on the over expressed Myr-Akt. This allowed us to examine the effects of other Akt mutations on necroptosis."}

{"project":"BioNLP16_Messiy","denotations":[{"id":"T15285","span":{"begin":140,"end":149},"obj":"Gene_expression"},{"id":"T15284","span":{"begin":101,"end":111},"obj":"Gene_expression"},{"id":"T15255","span":{"begin":150,"end":157},"obj":"Protein"},{"id":"T15254","span":{"begin":96,"end":100},"obj":"Protein"}],"relations":[{"id":"R10024","pred":"themeOf","subj":"T15254","obj":"T15284"},{"id":"R10025","pred":"themeOf","subj":"T15255","obj":"T15285"}],"text":"Under serum free conditions all zVAD.fmk-induced downstream events (cell death, JNK activation, TNFα production) were dependent on the over expressed Myr-Akt. This allowed us to examine the effects of other Akt mutations on necroptosis."}

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