PMC:3585731 / 15996-16233
Annnotations
testone
{"project":"testone","denotations":[{"id":"T5149","span":{"begin":207,"end":222},"obj":"Phosphorylation"},{"id":"T5148","span":{"begin":184,"end":192},"obj":"Positive_regulation"},{"id":"T5147","span":{"begin":55,"end":70},"obj":"Phosphorylation"},{"id":"T5088","span":{"begin":169,"end":173},"obj":"Protein"}],"relations":[{"id":"R3515","pred":"causeOf","subj":"T5088","obj":"T5148"},{"id":"R3536","pred":"themeOf","subj":"T5149","obj":"T5148"}],"text":"We confirmed the kinetics of the Akt Thr308 and Ser473 phosphorylation changes using a quantitative ELISA assay, which also showed a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation (Fig. S3D, E)."}
pmc-enju-pas
{"project":"pmc-enju-pas","denotations":[{"id":"T6310","span":{"begin":235,"end":236},"obj":"-RRB-"},{"id":"T6309","span":{"begin":234,"end":235},"obj":"NN"},{"id":"T6308","span":{"begin":232,"end":233},"obj":"-COMMA-"},{"id":"T6307","span":{"begin":229,"end":232},"obj":"NN"},{"id":"T6306","span":{"begin":224,"end":228},"obj":"NNP"},{"id":"T6305","span":{"begin":223,"end":224},"obj":"-LRB-"},{"id":"T6304","span":{"begin":207,"end":222},"obj":"NN"},{"id":"T6303","span":{"begin":200,"end":206},"obj":"NN"},{"id":"T6302","span":{"begin":196,"end":199},"obj":"NN"},{"id":"T6301","span":{"begin":193,"end":195},"obj":"IN"},{"id":"T6300","span":{"begin":184,"end":192},"obj":"NN"},{"id":"T6299","span":{"begin":169,"end":183},"obj":"JJ"},{"id":"T6298","span":{"begin":148,"end":168},"obj":"JJ"},{"id":"T6297","span":{"begin":140,"end":147},"obj":"VB"},{"id":"T6296","span":{"begin":133,"end":139},"obj":"JJ"},{"id":"T6295","span":{"begin":131,"end":132},"obj":"DT"},{"id":"T6294","span":{"begin":124,"end":130},"obj":"VB"},{"id":"T6293","span":{"begin":119,"end":123},"obj":"RB"},{"id":"T6292","span":{"begin":113,"end":118},"obj":"WDT"},{"id":"T6291","span":{"begin":111,"end":112},"obj":"-COMMA-"},{"id":"T6290","span":{"begin":106,"end":111},"obj":"NN"},{"id":"T6289","span":{"begin":100,"end":105},"obj":"NN"},{"id":"T6288","span":{"begin":87,"end":99},"obj":"JJ"},{"id":"T6287","span":{"begin":85,"end":86},"obj":"DT"},{"id":"T6286","span":{"begin":79,"end":84},"obj":"VB"},{"id":"T6285","span":{"begin":71,"end":78},"obj":"NN"},{"id":"T6284","span":{"begin":55,"end":70},"obj":"NN"},{"id":"T6283","span":{"begin":48,"end":54},"obj":"NN"},{"id":"T6282","span":{"begin":44,"end":47},"obj":"CC"},{"id":"T6281","span":{"begin":37,"end":43},"obj":"NN"},{"id":"T6280","span":{"begin":33,"end":36},"obj":"NN"},{"id":"T6279","span":{"begin":29,"end":32},"obj":"DT"},{"id":"T6278","span":{"begin":26,"end":28},"obj":"IN"},{"id":"T6277","span":{"begin":17,"end":25},"obj":"NN"},{"id":"T6276","span":{"begin":13,"end":16},"obj":"DT"},{"id":"T6275","span":{"begin":3,"end":12},"obj":"VB"},{"id":"T6274","span":{"begin":0,"end":2},"obj":"PRP"}],"relations":[{"id":"R4325","pred":"arg1Of","subj":"T6274","obj":"T6275"},{"id":"R4326","pred":"arg1Of","subj":"T6274","obj":"T6286"},{"id":"R4327","pred":"modOf","subj":"T6275","obj":"T6286"},{"id":"R4328","pred":"arg2Of","subj":"T6277","obj":"T6275"},{"id":"R4329","pred":"arg1Of","subj":"T6277","obj":"T6276"},{"id":"R4330","pred":"arg1Of","subj":"T6277","obj":"T6278"},{"id":"R4331","pred":"arg1Of","subj":"T6281","obj":"T6282"},{"id":"R4332","pred":"arg2Of","subj":"T6283","obj":"T6282"},{"id":"R4333","pred":"arg2Of","subj":"T6285","obj":"T6278"},{"id":"R4334","pred":"arg1Of","subj":"T6285","obj":"T6279"},{"id":"R4335","pred":"arg1Of","subj":"T6285","obj":"T6280"},{"id":"R4336","pred":"arg1Of","subj":"T6285","obj":"T6281"},{"id":"R4337","pred":"arg1Of","subj":"T6285","obj":"T6283"},{"id":"R4338","pred":"arg1Of","subj":"T6285","obj":"T6284"},{"id":"R4339","pred":"arg2Of","subj":"T6290","obj":"T6286"},{"id":"R4340","pred":"arg1Of","subj":"T6290","obj":"T6287"},{"id":"R4341","pred":"arg1Of","subj":"T6290","obj":"T6288"},{"id":"R4342","pred":"arg1Of","subj":"T6290","obj":"T6289"},{"id":"R4343","pred":"arg1Of","subj":"T6290","obj":"T6291"},{"id":"R4344","pred":"arg1Of","subj":"T6290","obj":"T6292"},{"id":"R4345","pred":"arg1Of","subj":"T6290","obj":"T6294"},{"id":"R4346","pred":"arg1Of","subj":"T6294","obj":"T6293"},{"id":"R4347","pred":"arg1Of","subj":"T6294","obj":"T6305"},{"id":"R4348","pred":"arg2Of","subj":"T6300","obj":"T6294"},{"id":"R4349","pred":"arg1Of","subj":"T6300","obj":"T6295"},{"id":"R4350","pred":"arg1Of","subj":"T6300","obj":"T6296"},{"id":"R4351","pred":"arg2Of","subj":"T6300","obj":"T6297"},{"id":"R4352","pred":"arg1Of","subj":"T6300","obj":"T6298"},{"id":"R4353","pred":"arg1Of","subj":"T6300","obj":"T6299"},{"id":"R4354","pred":"arg1Of","subj":"T6300","obj":"T6301"},{"id":"R4355","pred":"arg2Of","subj":"T6304","obj":"T6301"},{"id":"R4356","pred":"arg1Of","subj":"T6304","obj":"T6302"},{"id":"R4357","pred":"arg1Of","subj":"T6304","obj":"T6303"},{"id":"R4358","pred":"arg2Of","subj":"T6307","obj":"T6305"},{"id":"R4359","pred":"arg1Of","subj":"T6307","obj":"T6306"},{"id":"R4360","pred":"arg1Of","subj":"T6307","obj":"T6308"},{"id":"R4361","pred":"arg2Of","subj":"T6309","obj":"T6308"},{"id":"R4362","pred":"arg3Of","subj":"T6310","obj":"T6305"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"text":"We confirmed the kinetics of the Akt Thr308 and Ser473 phosphorylation changes using a quantitative ELISA assay, which also showed a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation (Fig. S3D, E)."}
bionlp-st-ge-2016-test-proteins
{"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T5399","span":{"begin":169,"end":173},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"We confirmed the kinetics of the Akt Thr308 and Ser473 phosphorylation changes using a quantitative ELISA assay, which also showed a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation (Fig. S3D, E)."}
bionlp-st-ge-2016-uniprot
{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T6490","span":{"begin":196,"end":199},"obj":"http://www.uniprot.org/uniprot/P31751"},{"id":"T6489","span":{"begin":33,"end":36},"obj":"http://www.uniprot.org/uniprot/P31751"},{"id":"T6434","span":{"begin":169,"end":173},"obj":"http://www.uniprot.org/uniprot/Q13546"},{"id":"T6518","span":{"begin":196,"end":199},"obj":"http://www.uniprot.org/uniprot/Q9Y243"},{"id":"T6517","span":{"begin":33,"end":36},"obj":"http://www.uniprot.org/uniprot/Q9Y243"},{"id":"T6462","span":{"begin":196,"end":199},"obj":"http://www.uniprot.org/uniprot/P31749"},{"id":"T6461","span":{"begin":33,"end":36},"obj":"http://www.uniprot.org/uniprot/P31749"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"We confirmed the kinetics of the Akt Thr308 and Ser473 phosphorylation changes using a quantitative ELISA assay, which also showed a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation (Fig. S3D, E)."}
GO-BP
{"project":"GO-BP","denotations":[{"id":"T5480","span":{"begin":207,"end":222},"obj":"http://purl.obolibrary.org/obo/GO_0016310"},{"id":"T5479","span":{"begin":55,"end":70},"obj":"http://purl.obolibrary.org/obo/GO_0016310"},{"id":"T5420","span":{"begin":148,"end":159},"obj":"http://purl.obolibrary.org/obo/GO_0097528"},{"id":"T5410","span":{"begin":148,"end":159},"obj":"http://purl.obolibrary.org/obo/GO_0070266"}],"text":"We confirmed the kinetics of the Akt Thr308 and Ser473 phosphorylation changes using a quantitative ELISA assay, which also showed a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation (Fig. S3D, E)."}
sentences
{"project":"sentences","denotations":[{"id":"T5308","span":{"begin":0,"end":237},"obj":"Sentence"},{"id":"T100","span":{"begin":0,"end":237},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"We confirmed the kinetics of the Akt Thr308 and Ser473 phosphorylation changes using a quantitative ELISA assay, which also showed a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation (Fig. S3D, E)."}
simple1
{"project":"simple1","denotations":[{"id":"T5552","span":{"begin":169,"end":173},"obj":"Protein"}],"text":"We confirmed the kinetics of the Akt Thr308 and Ser473 phosphorylation changes using a quantitative ELISA assay, which also showed a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation (Fig. S3D, E)."}
BioNLP16_DUT
{"project":"BioNLP16_DUT","denotations":[{"id":"T6411","span":{"begin":169,"end":173},"obj":"Protein"}],"text":"We confirmed the kinetics of the Akt Thr308 and Ser473 phosphorylation changes using a quantitative ELISA assay, which also showed a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation (Fig. S3D, E)."}
BioNLP16_Messiy
{"project":"BioNLP16_Messiy","denotations":[{"id":"T6692","span":{"begin":169,"end":173},"obj":"Protein"}],"text":"We confirmed the kinetics of the Akt Thr308 and Ser473 phosphorylation changes using a quantitative ELISA assay, which also showed a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation (Fig. S3D, E)."}
DLUT931
{"project":"DLUT931","denotations":[{"id":"T6572","span":{"begin":169,"end":173},"obj":"Protein"}],"text":"We confirmed the kinetics of the Akt Thr308 and Ser473 phosphorylation changes using a quantitative ELISA assay, which also showed a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation (Fig. S3D, E)."}
bionlp-st-ge-2016-test-ihmc
{"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T7300","span":{"begin":113,"end":222},"obj":"Positive_regulation"},{"id":"T7295","span":{"begin":131,"end":222},"obj":"Regulation"},{"id":"T7288","span":{"begin":193,"end":222},"obj":"Phosphorylation"},{"id":"T7283","span":{"begin":131,"end":222},"obj":"Negative_regulation"},{"id":"T7266","span":{"begin":33,"end":36},"obj":"Protein"},{"id":"T7242","span":{"begin":48,"end":54},"obj":"Entity"},{"id":"T7236","span":{"begin":196,"end":206},"obj":"Entity"},{"id":"T7222","span":{"begin":26,"end":43},"obj":"Entity"},{"id":"T7206","span":{"begin":224,"end":227},"obj":"Protein"},{"id":"T7205","span":{"begin":196,"end":199},"obj":"Protein"},{"id":"T7164","span":{"begin":169,"end":183},"obj":"Protein"}],"relations":[{"id":"R4707","pred":"causeOf","subj":"T7164","obj":"T7295"},{"id":"R4733","pred":"themeOf","subj":"T7205","obj":"T7288"},{"id":"R4749","pred":"partOf","subj":"T7236","obj":"T7205"},{"id":"R4750","pred":"siteOf","subj":"T7236","obj":"T7288"},{"id":"R4775","pred":"themeOf","subj":"T7288","obj":"T7300"},{"id":"R4776","pred":"themeOf","subj":"T7300","obj":"T7283"},{"id":"R4777","pred":"themeOf","subj":"T7300","obj":"T7295"}],"text":"We confirmed the kinetics of the Akt Thr308 and Ser473 phosphorylation changes using a quantitative ELISA assay, which also showed a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation (Fig. S3D, E)."}
bionlp-st-ge-2016-test-tees
{"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T6917","span":{"begin":55,"end":70},"obj":"Phosphorylation"},{"id":"T6916","span":{"begin":229,"end":232},"obj":"Protein"},{"id":"T6915","span":{"begin":224,"end":227},"obj":"Protein"},{"id":"T6914","span":{"begin":196,"end":199},"obj":"Protein"},{"id":"T6913","span":{"begin":169,"end":173},"obj":"Protein"},{"id":"T6912","span":{"begin":33,"end":43},"obj":"Protein"},{"id":"T6919","span":{"begin":184,"end":192},"obj":"Positive_regulation"},{"id":"T6918","span":{"begin":207,"end":222},"obj":"Phosphorylation"}],"relations":[{"id":"R4602","pred":"themeOf","subj":"T6918","obj":"T6919"},{"id":"R4617","pred":"themeOf","subj":"T6912","obj":"T6917"},{"id":"R4618","pred":"causeOf","subj":"T6913","obj":"T6919"},{"id":"R4620","pred":"themeOf","subj":"T6914","obj":"T6918"}],"text":"We confirmed the kinetics of the Akt Thr308 and Ser473 phosphorylation changes using a quantitative ELISA assay, which also showed a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation (Fig. S3D, E)."}
test3
{"project":"test3","denotations":[{"id":"T5274","span":{"begin":207,"end":222},"obj":"Phosphorylation"},{"id":"T5273","span":{"begin":184,"end":192},"obj":"Positive_regulation"},{"id":"T5272","span":{"begin":174,"end":183},"obj":"Regulation"},{"id":"T5271","span":{"begin":169,"end":173},"obj":"Protein"},{"id":"T5184","span":{"begin":169,"end":173},"obj":"Protein"}],"relations":[{"id":"R3577","pred":"causeOf","subj":"T5271","obj":"T5272"},{"id":"R3578","pred":"themeOf","subj":"T5273","obj":"T5272"},{"id":"R3579","pred":"themeOf","subj":"T5274","obj":"T5273"}],"text":"We confirmed the kinetics of the Akt Thr308 and Ser473 phosphorylation changes using a quantitative ELISA assay, which also showed a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation (Fig. S3D, E)."}