PMC:3543920 / 914-1431 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/3543920","sourcedb":"PMC","sourceid":"3543920","source_url":"https://www.ncbi.nlm.nih.gov/pmc/3543920","text":"Introduction\nWhole exome sequencing (WES) is a technique to selectively capture and sequence the coding regions of all annotated protein-coding genes. Coupled with next-generation sequencing (NGS) platforms, it enables the analysis of functional regions of the human genome with unprecedented efficiency. Since its first reported application [1, 2], WES has emerged as a powerful and popular tool for researchers elucidating genetic variants underlying human diseases (Fig. 1) despite certain limitations (see below).","divisions":[{"label":"Title","span":{"begin":0,"end":12}}],"tracks":[{"project":"2_test","denotations":[{"id":"23346032-19861545-44837241","span":{"begin":343,"end":344},"obj":"19861545"},{"id":"23346032-19684571-44837242","span":{"begin":346,"end":347},"obj":"19684571"}],"attributes":[{"subj":"23346032-19861545-44837241","pred":"source","obj":"2_test"},{"subj":"23346032-19684571-44837242","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#93ecc8","default":true}]}]}}