PMC:3506840 / 7344-8264 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/3506840","sourcedb":"PMC","sourceid":"3506840","source_url":"https://www.ncbi.nlm.nih.gov/pmc/3506840","text":"It is noteworthy that the bulbar symptom of this patient regressed spontaneously. She is now 25 years old, and is absolutely free of neurological symptoms, except for short stature with scoliosis, presumably a sign of AxD [9]. This case suggests that the symptoms of AxD can be self-remitting, unlike those of other neurodegenerative disorders, and that the prognosis might not necessarily be unfavorable. To our knowledge, no other AxD patient whose symptoms vanished for such a long period of time has been reported in the literature. Very recently, a case of adult-onset AxD with remission and relapse was reported, but the remission was only partial and lasted less than 5 years [10]; atypical AxD has been mistaken for remitting–relapsing multiple sclerosis [1]. Because the cervicomedullary atrophy continues to progress in our patient (Fig. 1B), she might still develop an adult form of the disease in the future.","tracks":[{"project":"AxD_symptoms","denotations":[{"id":"T33","span":{"begin":167,"end":180},"obj":"Phenotype"},{"id":"T34","span":{"begin":186,"end":195},"obj":"Phenotype"}],"attributes":[{"id":"A33","pred":"hp_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/HP_0004322"},{"id":"A34","pred":"hp_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/HP_0002650"},{"subj":"T33","pred":"source","obj":"AxD_symptoms"},{"subj":"T34","pred":"source","obj":"AxD_symptoms"}]},{"project":"2_test","denotations":[{"id":"22198646-19084454-75888811","span":{"begin":223,"end":224},"obj":"19084454"},{"id":"22198646-20562394-75888812","span":{"begin":684,"end":686},"obj":"20562394"}],"attributes":[{"subj":"22198646-19084454-75888811","pred":"source","obj":"2_test"},{"subj":"22198646-20562394-75888812","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"AxD_symptoms","color":"#9993ec","default":true},{"id":"2_test","color":"#a7ec93"}]}]}}