PMC:3431878 / 27787-28672 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/3431878","sourcedb":"PMC","sourceid":"3431878","source_url":"https://www.ncbi.nlm.nih.gov/pmc/3431878","text":"Table 1 Features described from the CA125 amino acid sequence based on the data of O’Brien [18,21], Yin [17], Maeda [22] and Berman [23]; Amino acid (aa) number (numbering derived from [18]) indicates the position of those residues as they appear within the respective domain. bp: base pairs.\nDomain Carboxy Domain Repeat Domain Amino Domain\nFeatures\nExons 9 5 9\nNucleotides (bp) 14,000 Single: 1900Cumulative: Unknown 50,950\nAmino Acids (aa) 284 Single: 156Cumulative: \u003e9360 12,068\nMolecular Characteristics Stop CodonPoly A SignalPotential Transmembrane Region (aa 230–252)Potential Cytoplasmic Region (aa 256–260)Potential ProteolyticCleavage Sites (aa 171–181 [18] and aa 35/36 [22]) SEA domainCysteine loop (aa 59,79) [23]Conserved Methionine (aa 24)Serine/Threonine/Proline Rich Serine/Threonine Rich(Abundant O-glycosylation Potential, N-glycosylation Potential)","divisions":[{"label":"label","span":{"begin":0,"end":7}},{"label":"caption","span":{"begin":9,"end":293}},{"label":"p","span":{"begin":9,"end":293}},{"label":"tr","span":{"begin":294,"end":345}},{"label":"th","span":{"begin":294,"end":300}},{"label":"th","span":{"begin":302,"end":316}},{"label":"th","span":{"begin":318,"end":331}},{"label":"th","span":{"begin":333,"end":345}},{"label":"tr","span":{"begin":346,"end":354}},{"label":"th","span":{"begin":346,"end":354}},{"label":"tr","span":{"begin":355,"end":369}},{"label":"td","span":{"begin":355,"end":360}},{"label":"td","span":{"begin":362,"end":363}},{"label":"td","span":{"begin":365,"end":366}},{"label":"td","span":{"begin":368,"end":369}},{"label":"tr","span":{"begin":370,"end":435}},{"label":"td","span":{"begin":370,"end":386}},{"label":"td","span":{"begin":388,"end":394}},{"label":"td","span":{"begin":396,"end":427}},{"label":"td","span":{"begin":429,"end":435}},{"label":"tr","span":{"begin":436,"end":495}},{"label":"td","span":{"begin":436,"end":452}},{"label":"td","span":{"begin":454,"end":457}},{"label":"td","span":{"begin":459,"end":487}},{"label":"td","span":{"begin":489,"end":495}},{"label":"td","span":{"begin":496,"end":521}},{"label":"td","span":{"begin":523,"end":701}},{"label":"td","span":{"begin":703,"end":799}}],"tracks":[]}