PMC:340383 / 9401-10071
Annnotations
craft-sa-dev
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CBS domains are small intracellular modules that are mostly found in 2 or four copies within a protein. Pairs of CBS domains dimerise to form a stable globular domain [8]. DUF21 (CD: pfam01959.9) is a newly defined domain with unknown function. This domain is a transmembrane region and found to be located in the N-terminus of the proteins adjacent to two intracellular CBS domains . A cNMP-binding domain (cyclic nucleotide-monophosphate-binding domain) was found in all Acdp members."}
craft-ca-core-dev
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2_test
{"project":"2_test","denotations":[{"id":"14723793-9020585-10642189","span":{"begin":352,"end":353},"obj":"9020585"}],"text":"We found that all mouse Acdp members contain four distinct transmembrane domains (Fig. 5), two CBS domains and a DUF21 domain that are found in bacteria CorC and yeast Amip3 proteins. CBS domains are small intracellular modules that are mostly found in 2 or four copies within a protein. Pairs of CBS domains dimerise to form a stable globular domain [8]. DUF21 (CD: pfam01959.9) is a newly defined domain with unknown function. This domain is a transmembrane region and found to be located in the N-terminus of the proteins adjacent to two intracellular CBS domains . A cNMP-binding domain (cyclic nucleotide-monophosphate-binding domain) was found in all Acdp members."}
craft-ca-core-ex-dev
{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T2005","span":{"begin":657,"end":661},"obj":"PR_EXT:ACDP_or_CNNM"},{"id":"T2004","span":{"begin":632,"end":638},"obj":"SO_EXT:0000417"},{"id":"T2003","span":{"begin":624,"end":631},"obj":"CHEMINF_GO_EXT:chemical_binding_or_bond_formation"},{"id":"T2002","span":{"begin":584,"end":590},"obj":"SO_EXT:0000417"},{"id":"T2001","span":{"begin":576,"end":583},"obj":"CHEMINF_GO_EXT:chemical_binding_or_bond_formation"},{"id":"T2000","span":{"begin":559,"end":566},"obj":"SO_EXT:0000417"},{"id":"T1999","span":{"begin":546,"end":554},"obj":"CL_GO_EXT:cell"},{"id":"T1998","span":{"begin":541,"end":554},"obj":"GO:0005622"},{"id":"T1997","span":{"begin":516,"end":524},"obj":"CHEBI_PR_EXT:protein"},{"id":"T1996","span":{"begin":498,"end":508},"obj":"CHEBI_SO_EXT:N_terminus_or_N_terminal_region"},{"id":"T1995","span":{"begin":451,"end":459},"obj":"GO:0016020"},{"id":"T1994","span":{"begin":446,"end":466},"obj":"SO_EXT:0001077"},{"id":"T1989","span":{"begin":301,"end":308},"obj":"SO_EXT:0000417"},{"id":"T1993","span":{"begin":434,"end":440},"obj":"SO_EXT:0000417"},{"id":"T1992","span":{"begin":399,"end":405},"obj":"SO_EXT:0000417"},{"id":"T1991","span":{"begin":344,"end":350},"obj":"SO_EXT:0000417"},{"id":"T1990","span":{"begin":309,"end":317},"obj":"GO:0046983"},{"id":"T1988","span":{"begin":279,"end":286},"obj":"CHEBI_PR_EXT:protein"},{"id":"T1987","span":{"begin":263,"end":269},"obj":"SO_EXT:sequence_copy_entity"},{"id":"T1986","span":{"begin":220,"end":227},"obj":"SO_EXT:0000417"},{"id":"T1985","span":{"begin":211,"end":219},"obj":"CL_GO_EXT:cell"},{"id":"T1984","span":{"begin":206,"end":219},"obj":"GO:0005622"},{"id":"T1983","span":{"begin":188,"end":195},"obj":"SO_EXT:0000417"},{"id":"T1982","span":{"begin":174,"end":182},"obj":"CHEBI_PR_EXT:protein"},{"id":"T1981","span":{"begin":162,"end":167},"obj":"NCBITaxon_EXT:yeast"},{"id":"T1980","span":{"begin":153,"end":157},"obj":"PR_EXT:000022321"},{"id":"T1979","span":{"begin":144,"end":152},"obj":"NCBITaxon:2"},{"id":"T1978","span":{"begin":119,"end":125},"obj":"SO_EXT:0000417"},{"id":"T1977","span":{"begin":99,"end":106},"obj":"SO_EXT:0000417"},{"id":"T1976","span":{"begin":73,"end":80},"obj":"SO_EXT:0000417"},{"id":"T1975","span":{"begin":64,"end":72},"obj":"GO:0016020"},{"id":"T1974","span":{"begin":24,"end":28},"obj":"PR_EXT:ACDP_or_CNNM"},{"id":"T1973","span":{"begin":18,"end":23},"obj":"NCBITaxon:10088"}],"text":"We found that all mouse Acdp members contain four distinct transmembrane domains (Fig. 5), two CBS domains and a DUF21 domain that are found in bacteria CorC and yeast Amip3 proteins. CBS domains are small intracellular modules that are mostly found in 2 or four copies within a protein. Pairs of CBS domains dimerise to form a stable globular domain [8]. DUF21 (CD: pfam01959.9) is a newly defined domain with unknown function. This domain is a transmembrane region and found to be located in the N-terminus of the proteins adjacent to two intracellular CBS domains . A cNMP-binding domain (cyclic nucleotide-monophosphate-binding domain) was found in all Acdp members."}