PMC:340383 / 1324-1716 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/340383","sourcedb":"PMC","sourceid":"340383","source_url":"http://www.ncbi.nlm.nih.gov/pmc/340383","text":"The Acdp genes are evolutionarily conserved in diverse species and ubiquitously expressed throughout development and adult tissues suggesting that Acdp may be an essential gene. Acdp showed strong homology to bacteria CorC protein and predominantly localized on the plasma membrane. These results suggest that Acdp is probably a family of proteins involved in ion transport in mammalian cells","tracks":[{"project":"craft-sa-dev","denotations":[{"id":"T470","span":{"begin":0,"end":3},"obj":"DT"},{"id":"T471","span":{"begin":9,"end":14},"obj":"NNS"},{"id":"T472","span":{"begin":4,"end":8},"obj":"NN"},{"id":"T473","span":{"begin":34,"end":43},"obj":"VBN"},{"id":"T474","span":{"begin":15,"end":18},"obj":"VBP"},{"id":"T475","span":{"begin":19,"end":33},"obj":"RB"},{"id":"T476","span":{"begin":44,"end":46},"obj":"IN"},{"id":"T477","span":{"begin":47,"end":54},"obj":"JJ"},{"id":"T478","span":{"begin":55,"end":62},"obj":"NNS"},{"id":"T479","span":{"begin":63,"end":66},"obj":"CC"},{"id":"T480","span":{"begin":67,"end":79},"obj":"RB"},{"id":"T481","span":{"begin":80,"end":89},"obj":"VBN"},{"id":"T482","span":{"begin":90,"end":100},"obj":"IN"},{"id":"T483","span":{"begin":101,"end":112},"obj":"NN"},{"id":"T484","span":{"begin":113,"end":116},"obj":"CC"},{"id":"T485","span":{"begin":117,"end":122},"obj":"JJ"},{"id":"T486","span":{"begin":123,"end":130},"obj":"NNS"},{"id":"T487","span":{"begin":131,"end":141},"obj":"VBG"},{"id":"T488","span":{"begin":142,"end":146},"obj":"IN"},{"id":"T489","span":{"begin":156,"end":158},"obj":"VB"},{"id":"T490","span":{"begin":147,"end":151},"obj":"NN"},{"id":"T491","span":{"begin":152,"end":155},"obj":"MD"},{"id":"T492","span":{"begin":159,"end":161},"obj":"DT"},{"id":"T493","span":{"begin":172,"end":176},"obj":"NN"},{"id":"T494","span":{"begin":162,"end":171},"obj":"JJ"},{"id":"T495","span":{"begin":176,"end":177},"obj":"."},{"id":"T496","span":{"begin":177,"end":282},"obj":"sentence"},{"id":"T497","span":{"begin":178,"end":182},"obj":"NN"},{"id":"T498","span":{"begin":183,"end":189},"obj":"VBD"},{"id":"T499","span":{"begin":190,"end":196},"obj":"JJ"},{"id":"T500","span":{"begin":197,"end":205},"obj":"NN"},{"id":"T501","span":{"begin":206,"end":208},"obj":"IN"},{"id":"T502","span":{"begin":209,"end":217},"obj":"NNS"},{"id":"T503","span":{"begin":223,"end":230},"obj":"NN"},{"id":"T504","span":{"begin":218,"end":222},"obj":"NN"},{"id":"T505","span":{"begin":231,"end":234},"obj":"CC"},{"id":"T506","span":{"begin":235,"end":248},"obj":"RB"},{"id":"T507","span":{"begin":249,"end":258},"obj":"VBD"},{"id":"T508","span":{"begin":259,"end":261},"obj":"IN"},{"id":"T509","span":{"begin":262,"end":265},"obj":"DT"},{"id":"T510","span":{"begin":273,"end":281},"obj":"NN"},{"id":"T511","span":{"begin":266,"end":272},"obj":"NN"},{"id":"T512","span":{"begin":281,"end":282},"obj":"."},{"id":"T513","span":{"begin":282,"end":392},"obj":"sentence"},{"id":"T514","span":{"begin":283,"end":288},"obj":"DT"},{"id":"T515","span":{"begin":289,"end":296},"obj":"NNS"},{"id":"T516","span":{"begin":297,"end":304},"obj":"VBP"},{"id":"T517","span":{"begin":305,"end":309},"obj":"IN"},{"id":"T518","span":{"begin":315,"end":317},"obj":"VBZ"},{"id":"T519","span":{"begin":310,"end":314},"obj":"NN"},{"id":"T520","span":{"begin":318,"end":326},"obj":"RB"},{"id":"T521","span":{"begin":327,"end":328},"obj":"DT"},{"id":"T522","span":{"begin":329,"end":335},"obj":"NN"},{"id":"T523","span":{"begin":336,"end":338},"obj":"IN"},{"id":"T524","span":{"begin":339,"end":347},"obj":"NN"},{"id":"T525","span":{"begin":348,"end":356},"obj":"VBN"},{"id":"T526","span":{"begin":357,"end":359},"obj":"IN"},{"id":"T527","span":{"begin":360,"end":363},"obj":"NN"},{"id":"T528","span":{"begin":364,"end":373},"obj":"NN"},{"id":"T529","span":{"begin":374,"end":376},"obj":"IN"},{"id":"T530","span":{"begin":377,"end":386},"obj":"JJ"},{"id":"T531","span":{"begin":387,"end":392},"obj":"NNS"}],"relations":[{"id":"R230","pred":"det","subj":"T470","obj":"T471"},{"id":"R232","pred":"compound","subj":"T472","obj":"T471"},{"id":"R233","pred":"auxpass","subj":"T474","obj":"T473"},{"id":"R234","pred":"advmod","subj":"T475","obj":"T473"},{"id":"R235","pred":"prep","subj":"T476","obj":"T473"},{"id":"R236","pred":"amod","subj":"T477","obj":"T478"},{"id":"R237","pred":"pobj","subj":"T478","obj":"T476"},{"id":"R238","pred":"cc","subj":"T479","obj":"T473"},{"id":"R239","pred":"advmod","subj":"T480","obj":"T481"},{"id":"R240","pred":"conj","subj":"T481","obj":"T473"},{"id":"R241","pred":"prep","subj":"T482","obj":"T481"},{"id":"R242","pred":"pobj","subj":"T483","obj":"T482"},{"id":"R243","pred":"cc","subj":"T484","obj":"T483"},{"id":"R244","pred":"amod","subj":"T485","obj":"T486"},{"id":"R245","pred":"conj","subj":"T486","obj":"T483"},{"id":"R246","pred":"advcl","subj":"T487","obj":"T473"},{"id":"R247","pred":"mark","subj":"T488","obj":"T489"},{"id":"R248","pred":"ccomp","subj":"T489","obj":"T487"},{"id":"R249","pred":"nsubj","subj":"T490","obj":"T489"},{"id":"R250","pred":"aux","subj":"T491","obj":"T489"},{"id":"R251","pred":"det","subj":"T492","obj":"T493"},{"id":"R253","pred":"amod","subj":"T494","obj":"T493"},{"id":"R254","pred":"punct","subj":"T495","obj":"T473"},{"id":"R255","pred":"nsubj","subj":"T497","obj":"T498"},{"id":"R256","pred":"amod","subj":"T499","obj":"T500"},{"id":"R257","pred":"dobj","subj":"T500","obj":"T498"},{"id":"R258","pred":"prep","subj":"T501","obj":"T498"},{"id":"R259","pred":"compound","subj":"T502","obj":"T503"},{"id":"R261","pred":"compound","subj":"T504","obj":"T503"},{"id":"R262","pred":"cc","subj":"T505","obj":"T498"},{"id":"R263","pred":"advmod","subj":"T506","obj":"T507"},{"id":"R264","pred":"conj","subj":"T507","obj":"T498"},{"id":"R265","pred":"prep","subj":"T508","obj":"T507"},{"id":"R266","pred":"det","subj":"T509","obj":"T510"},{"id":"R268","pred":"compound","subj":"T511","obj":"T510"},{"id":"R269","pred":"punct","subj":"T512","obj":"T498"},{"id":"R270","pred":"det","subj":"T514","obj":"T515"},{"id":"R271","pred":"nsubj","subj":"T515","obj":"T516"},{"id":"R272","pred":"mark","subj":"T517","obj":"T518"},{"id":"R274","pred":"nsubj","subj":"T519","obj":"T518"},{"id":"R275","pred":"advmod","subj":"T520","obj":"T518"},{"id":"R276","pred":"det","subj":"T521","obj":"T522"},{"id":"R277","pred":"attr","subj":"T522","obj":"T518"},{"id":"R278","pred":"prep","subj":"T523","obj":"T522"},{"id":"R279","pred":"pobj","subj":"T524","obj":"T523"},{"id":"R280","pred":"acl","subj":"T525","obj":"T524"},{"id":"R281","pred":"prep","subj":"T526","obj":"T525"},{"id":"R282","pred":"compound","subj":"T527","obj":"T528"},{"id":"R283","pred":"pobj","subj":"T528","obj":"T526"},{"id":"R284","pred":"prep","subj":"T529","obj":"T525"},{"id":"R285","pred":"amod","subj":"T530","obj":"T531"},{"id":"R286","pred":"pobj","subj":"T531","obj":"T529"},{"id":"R231","pred":"nsubjpass","subj":"T471","obj":"T473"},{"id":"R252","pred":"attr","subj":"T493","obj":"T489"},{"id":"R260","pred":"pobj","subj":"T503","obj":"T501"},{"id":"R267","pred":"pobj","subj":"T510","obj":"T508"},{"id":"R273","pred":"ccomp","subj":"T518","obj":"T516"}],"attributes":[{"subj":"T470","pred":"source","obj":"craft-sa-dev"},{"subj":"T471","pred":"source","obj":"craft-sa-dev"},{"subj":"T472","pred":"source","obj":"craft-sa-dev"},{"subj":"T473","pred":"source","obj":"craft-sa-dev"},{"subj":"T474","pred":"source","obj":"craft-sa-dev"},{"subj":"T475","pred":"source","obj":"craft-sa-dev"},{"subj":"T476","pred":"source","obj":"craft-sa-dev"},{"subj":"T477","pred":"source","obj":"craft-sa-dev"},{"subj":"T478","pred":"source","obj":"craft-sa-dev"},{"subj":"T479","pred":"source","obj":"craft-sa-dev"},{"subj":"T480","pred":"source","obj":"craft-sa-dev"},{"subj":"T481","pred":"source","obj":"craft-sa-dev"},{"subj":"T482","pred":"source","obj":"craft-sa-dev"},{"subj":"T483","pred":"source","obj":"craft-sa-dev"},{"subj":"T484","pred":"source","obj":"craft-sa-dev"},{"subj":"T485","pred":"source","obj":"craft-sa-dev"},{"subj":"T486","pred":"source","obj":"craft-sa-dev"},{"subj":"T487","pred":"source","obj":"craft-sa-dev"},{"subj":"T488","pred":"source","obj":"craft-sa-dev"},{"subj":"T489","pred":"source","obj":"craft-sa-dev"},{"subj":"T490","pred":"source","obj":"craft-sa-dev"},{"subj":"T491","pred":"source","obj":"craft-sa-dev"},{"subj":"T492","pred":"source","obj":"craft-sa-dev"},{"subj":"T493","pred":"source","obj":"craft-sa-dev"},{"subj":"T494","pred":"source","obj":"craft-sa-dev"},{"subj":"T495","pred":"source","obj":"craft-sa-dev"},{"subj":"T496","pred":"source","obj":"craft-sa-dev"},{"subj":"T497","pred":"source","obj":"craft-sa-dev"},{"subj":"T498","pred":"source","obj":"craft-sa-dev"},{"subj":"T499","pred":"source","obj":"craft-sa-dev"},{"subj":"T500","pred":"source","obj":"craft-sa-dev"},{"subj":"T501","pred":"source","obj":"craft-sa-dev"},{"subj":"T502","pred":"source","obj":"craft-sa-dev"},{"subj":"T503","pred":"source","obj":"craft-sa-dev"},{"subj":"T504","pred":"source","obj":"craft-sa-dev"},{"subj":"T505","pred":"source","obj":"craft-sa-dev"},{"subj":"T506","pred":"source","obj":"craft-sa-dev"},{"subj":"T507","pred":"source","obj":"craft-sa-dev"},{"subj":"T508","pred":"source","obj":"craft-sa-dev"},{"subj":"T509","pred":"source","obj":"craft-sa-dev"},{"subj":"T510","pred":"source","obj":"craft-sa-dev"},{"subj":"T511","pred":"source","obj":"craft-sa-dev"},{"subj":"T512","pred":"source","obj":"craft-sa-dev"},{"subj":"T513","pred":"source","obj":"craft-sa-dev"},{"subj":"T514","pred":"source","obj":"craft-sa-dev"},{"subj":"T515","pred":"source","obj":"craft-sa-dev"},{"subj":"T516","pred":"source","obj":"craft-sa-dev"},{"subj":"T517","pred":"source","obj":"craft-sa-dev"},{"subj":"T518","pred":"source","obj":"craft-sa-dev"},{"subj":"T519","pred":"source","obj":"craft-sa-dev"},{"subj":"T520","pred":"source","obj":"craft-sa-dev"},{"subj":"T521","pred":"source","obj":"craft-sa-dev"},{"subj":"T522","pred":"source","obj":"craft-sa-dev"},{"subj":"T523","pred":"source","obj":"craft-sa-dev"},{"subj":"T524","pred":"source","obj":"craft-sa-dev"},{"subj":"T525","pred":"source","obj":"craft-sa-dev"},{"subj":"T526","pred":"source","obj":"craft-sa-dev"},{"subj":"T527","pred":"source","obj":"craft-sa-dev"},{"subj":"T528","pred":"source","obj":"craft-sa-dev"},{"subj":"T529","pred":"source","obj":"craft-sa-dev"},{"subj":"T530","pred":"source","obj":"craft-sa-dev"},{"subj":"T531","pred":"source","obj":"craft-sa-dev"}]},{"project":"craft-ca-core-dev","denotations":[{"id":"T100","span":{"begin":9,"end":14},"obj":"SO:0000704"},{"id":"T101","span":{"begin":55,"end":62},"obj":"NCBITaxon:species"},{"id":"T102","span":{"begin":80,"end":89},"obj":"GO:0010467"},{"id":"T103","span":{"begin":117,"end":122},"obj":"UBERON:0007023"},{"id":"T104","span":{"begin":123,"end":130},"obj":"UBERON:0000479"},{"id":"T105","span":{"begin":172,"end":176},"obj":"SO:0000704"},{"id":"T106","span":{"begin":197,"end":205},"obj":"SO:0000857"},{"id":"T107","span":{"begin":209,"end":217},"obj":"NCBITaxon:2"},{"id":"T108","span":{"begin":218,"end":222},"obj":"PR:000022321"},{"id":"T109","span":{"begin":266,"end":281},"obj":"GO:0005886"},{"id":"T110","span":{"begin":360,"end":363},"obj":"CHEBI:24870"},{"id":"T111","span":{"begin":360,"end":373},"obj":"GO:0006811"},{"id":"T112","span":{"begin":364,"end":376},"obj":"_FRAGMENT"},{"id":"T113","span":{"begin":387,"end":392},"obj":"GO:0046907"},{"id":"T114","span":{"begin":377,"end":386},"obj":"NCBITaxon:40674"}],"relations":[{"id":"R1","pred":"_lexicallyChainedTo","subj":"T113","obj":"T112"}],"attributes":[{"subj":"T100","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T101","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T102","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T103","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T104","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T105","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T106","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T107","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T108","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T109","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T110","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T111","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T112","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T113","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T114","pred":"source","obj":"craft-ca-core-dev"}]},{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T192","span":{"begin":4,"end":8},"obj":"PR_EXT:ACDP_or_CNNM"},{"id":"T193","span":{"begin":9,"end":14},"obj":"SO_EXT:0000704"},{"id":"T194","span":{"begin":19,"end":43},"obj":"SO_EXT:biological_conservation_process_or_quality"},{"id":"T195","span":{"begin":55,"end":62},"obj":"NCBITaxon:species"},{"id":"T196","span":{"begin":80,"end":89},"obj":"GO:0010467"},{"id":"T197","span":{"begin":117,"end":122},"obj":"UBERON:0007023"},{"id":"T198","span":{"begin":123,"end":130},"obj":"UBERON:0000479"},{"id":"T199","span":{"begin":147,"end":151},"obj":"PR_EXT:ACDP_or_CNNM"},{"id":"T200","span":{"begin":172,"end":176},"obj":"SO_EXT:0000704"},{"id":"T201","span":{"begin":178,"end":182},"obj":"PR_EXT:ACDP_or_CNNM"},{"id":"T202","span":{"begin":197,"end":205},"obj":"SO:0000857"},{"id":"T203","span":{"begin":209,"end":217},"obj":"NCBITaxon:2"},{"id":"T204","span":{"begin":218,"end":222},"obj":"PR_EXT:000022321"},{"id":"T205","span":{"begin":223,"end":230},"obj":"CHEBI_PR_EXT:protein"},{"id":"T206","span":{"begin":249,"end":258},"obj":"GO_PATO_EXT:biological_localization_process_or_quality"},{"id":"T207","span":{"begin":266,"end":281},"obj":"GO:0005886"},{"id":"T208","span":{"begin":310,"end":314},"obj":"PR_EXT:ACDP_or_CNNM"},{"id":"T209","span":{"begin":339,"end":347},"obj":"CHEBI_PR_EXT:protein"},{"id":"T210","span":{"begin":360,"end":363},"obj":"CHEBI:24870"},{"id":"T211","span":{"begin":360,"end":373},"obj":"GO:0006811"},{"id":"T212","span":{"begin":364,"end":376},"obj":"_FRAGMENT"},{"id":"T213","span":{"begin":387,"end":392},"obj":"GO:0046907"},{"id":"T214","span":{"begin":377,"end":386},"obj":"NCBITaxon:40674"},{"id":"T215","span":{"begin":387,"end":392},"obj":"CL_GO_EXT:cell"}],"relations":[{"id":"R2","pred":"_lexicallyChainedTo","subj":"T213","obj":"T212"}],"attributes":[{"subj":"T192","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T193","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T194","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T195","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T196","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T197","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T198","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T199","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T200","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T201","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T202","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T203","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T204","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T205","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T206","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T207","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T208","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T209","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T210","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T211","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T212","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T213","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T214","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T215","pred":"source","obj":"craft-ca-core-ex-dev"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"craft-sa-dev","color":"#98ec93","default":true},{"id":"craft-ca-core-dev","color":"#ec93b2"},{"id":"craft-ca-core-ex-dev","color":"#93ccec"}]}]}}