PMC:3359311 / 653-1502
Annnotations
bionlp-st-ge-2016-uniprot
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T369 | 104-109 | P01584 | denotes | IL-1β |
| T370 | 358-363 | P01584 | denotes | IL-1β |
| T371 | 528-533 | P01584 | denotes | IL-1β |
| T372 | 596-601 | P01584 | denotes | IL-1β |
| T373 | 795-800 | P01584 | denotes | IL-1β |
| T374 | 804-808 | P10145 | denotes | IL-8 |
bionlp-st-ge-2016-reference
| Id | Subject | Object | Predicate | Lexical cue | Negation |
|---|---|---|---|---|---|
| T49 | 54-61 | Gene_expression | denotes | produce | true |
| T50 | 93-103 | Positive_regulation | denotes | stimulated | |
| T51 | 104-109 | Protein | denotes | IL-1β | |
| T52 | 332-340 | Gene_expression | denotes | produced | |
| T53 | 358-363 | Protein | denotes | IL-1β | |
| T54 | 408-412 | Positive_regulation | denotes | upon | |
| T55 | 528-533 | Protein | denotes | IL-1β | |
| T56 | 534-544 | Gene_expression | denotes | production | |
| T57 | 550-560 | Positive_regulation | denotes | stimulated | |
| T58 | 596-601 | Protein | denotes | IL-1β | |
| T59 | 789-794 | Regulation | denotes | alter | true |
| T60 | 795-800 | Protein | denotes | IL-1β | |
| T61 | 809-819 | Gene_expression | denotes | production | |
| T62 | 820-834 | Positive_regulation | denotes | in response to | |
| R30 | T49 | T50 | themeOf | produce,stimulated | |
| R31 | T51 | T49 | themeOf | IL-1β,produce | |
| R32 | T52 | T54 | themeOf | produced,upon | |
| R33 | T53 | T52 | themeOf | IL-1β,produced | |
| R34 | T55 | T56 | themeOf | IL-1β,production | |
| R35 | T56 | T57 | themeOf | production,stimulated | |
| R36 | T60 | T61 | themeOf | IL-1β,production | |
| R37 | T61 | T62 | themeOf | production,in response to | |
| R38 | T62 | T59 | themeOf | in response to,alter |
bionlp-st-ge-2016-reference-tees
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T809 | 104-109 | Protein | denotes | IL-1β |
| T810 | 184-193 | Protein | denotes | caspase-1 |
| T811 | 54-61 | Gene_expression | denotes | produce |
| T812 | 173-183 | Positive_regulation | denotes | upregulate |
| T813 | 358-363 | Protein | denotes | IL-1β |
| T814 | 389-398 | Protein | denotes | caspase-1 |
| T815 | 332-340 | Gene_expression | denotes | produced |
| T816 | 377-388 | Positive_regulation | denotes | upregulated |
| T817 | 347-354 | Positive_regulation | denotes | amounts |
| T818 | 503-512 | Protein | denotes | caspase-1 |
| T819 | 528-533 | Protein | denotes | IL-1β |
| T820 | 513-523 | Positive_regulation | denotes | activation |
| T821 | 534-544 | Gene_expression | denotes | production |
| T822 | 513-523 | Positive_regulation | denotes | activation |
| T823 | 596-601 | Protein | denotes | IL-1β |
| T824 | 630-635 | Protein | denotes | NF-κB |
| T825 | 602-612 | Gene_expression | denotes | production |
| T826 | 617-626 | Positive_regulation | denotes | dependent |
| T827 | 658-666 | Positive_regulation | denotes | enhanced |
| T828 | 720-724 | Protein | denotes | CFTR |
| T829 | 795-800 | Protein | denotes | IL-1β |
| T830 | 804-808 | Protein | denotes | IL-8 |
| T831 | 706-716 | Negative_regulation | denotes | inhibition |
| T832 | 809-819 | Gene_expression | denotes | production |
| T833 | 809-819 | Gene_expression | denotes | production |
| T834 | 789-794 | Positive_regulation | denotes | alter |
| T835 | 789-794 | Positive_regulation | denotes | alter |
| R670 | T809 | T811 | themeOf | IL-1β,produce |
| R671 | T810 | T812 | themeOf | caspase-1,upregulate |
| R672 | T813 | T815 | themeOf | IL-1β,produced |
| R673 | T814 | T816 | themeOf | caspase-1,upregulated |
| R674 | T816 | T817 | themeOf | upregulated,amounts |
| R675 | T818 | T820 | themeOf | caspase-1,activation |
| R676 | T819 | T821 | themeOf | IL-1β,production |
| R677 | T821 | T822 | themeOf | production,activation |
| R678 | T823 | T825 | themeOf | IL-1β,production |
| R679 | T825 | T826 | themeOf | production,dependent |
| R680 | T825 | T827 | themeOf | production,enhanced |
| R681 | T828 | T831 | themeOf | CFTR,inhibition |
| R682 | T829 | T832 | themeOf | IL-1β,production |
| R683 | T830 | T833 | themeOf | IL-8,production |
| R684 | T832 | T834 | themeOf | production,alter |
| R685 | T833 | T835 | themeOf | production,alter |
events-check-again
| Id | Subject | Object | Predicate | Lexical cue | Negation |
|---|---|---|---|---|---|
| T779 | 54-61 | Gene_expression | denotes | produce | true |
| T780 | 93-103 | Positive_regulation | denotes | stimulated | |
| T781 | 104-109 | Protein | denotes | IL-1β | |
| T782 | 332-340 | Gene_expression | denotes | produced | |
| T783 | 358-363 | Protein | denotes | IL-1β | |
| T784 | 408-412 | Positive_regulation | denotes | upon | |
| T785 | 528-533 | Protein | denotes | IL-1β | |
| T786 | 534-544 | Gene_expression | denotes | production | |
| T787 | 550-560 | Positive_regulation | denotes | stimulated | |
| T788 | 596-601 | Protein | denotes | IL-1β | |
| T789 | 789-794 | Regulation | denotes | alter | true |
| T790 | 795-800 | Protein | denotes | IL-1β | |
| T791 | 809-819 | Gene_expression | denotes | production | |
| T792 | 820-834 | Positive_regulation | denotes | in response to | |
| R652 | T779 | T780 | themeOf | produce,stimulated | |
| R653 | T781 | T779 | themeOf | IL-1β,produce | |
| R654 | T782 | T784 | themeOf | produced,upon | |
| R655 | T783 | T782 | themeOf | IL-1β,produced | |
| R656 | T785 | T786 | themeOf | IL-1β,production | |
| R657 | T786 | T787 | themeOf | production,stimulated | |
| R658 | T790 | T791 | themeOf | IL-1β,production | |
| R659 | T791 | T792 | themeOf | production,in response to | |
| R660 | T792 | T789 | themeOf | in response to,alter |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T689 | 29-33 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T690 | 136-141 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T691 | 276-281 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T692 | 761-766 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
GO-MF
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T696 | 804-808 | http://purl.obolibrary.org/obo/GO_0005153 | denotes | IL-8 |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T686 | 804-819 | http://purl.obolibrary.org/obo/GO_0032677 | denotes | IL-8 production |
| T687 | 804-819 | http://purl.obolibrary.org/obo/GO_0032637 | denotes | IL-8 production |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T36 | 258-263 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
bionlp-st-ge-2016-spacy-parsed
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T467 | 0-7 | NNS | denotes | Results |
| T468 | 8-17 | NNP | denotes | Bronchial |
| T469 | 18-28 | JJ | denotes | epithelial |
| T470 | 29-33 | NN | denotes | cell |
| T471 | 34-39 | NNS | denotes | lines |
| T472 | 40-44 | VBD | denotes | were |
| T473 | 45-50 | VBN | denotes | found |
| T474 | 51-53 | TO | denotes | to |
| T475 | 54-61 | VB | denotes | produce |
| T476 | 62-72 | JJ | denotes | negligible |
| T477 | 73-80 | NNS | denotes | amounts |
| T478 | 81-83 | IN | denotes | of |
| T479 | 84-89 | NN | denotes | basal |
| T480 | 90-92 | CC | denotes | or |
| T481 | 93-103 | VBN | denotes | stimulated |
| T482 | 104-109 | NN | denotes | IL-1β |
| T483 | 110-118 | VBN | denotes | compared |
| T484 | 119-121 | TO | denotes | to |
| T485 | 122-135 | JJ | denotes | hematopoeitic |
| T486 | 136-141 | NNS | denotes | cells |
| T487 | 142-145 | CC | denotes | and |
| T488 | 146-150 | PRP | denotes | they |
| T489 | 151-154 | VBD | denotes | did |
| T490 | 155-158 | RB | denotes | not |
| T491 | 159-172 | RB | denotes | significantly |
| T492 | 173-183 | VB | denotes | upregulate |
| T493 | 184-193 | JJ | denotes | caspase-1 |
| T494 | 194-202 | NN | denotes | activity |
| T495 | 203-207 | IN | denotes | upon |
| T496 | 208-220 | JJ | denotes | inflammasome |
| T497 | 221-232 | NN | denotes | stimulation |
| T498 | 232-233 | . | denotes | . |
| T499 | 234-236 | IN | denotes | In |
| T500 | 237-245 | NN | denotes | contrast |
| T501 | 245-246 | , | denotes | , |
| T502 | 247-257 | JJ | denotes | peripheral |
| T503 | 258-263 | NN | denotes | blood |
| T504 | 264-275 | NN | denotes | mononuclear |
| T505 | 276-281 | NNS | denotes | cells |
| T506 | 282-283 | -LRB- | denotes | ( |
| T507 | 283-288 | NNS | denotes | PBMCs |
| T508 | 288-289 | -RRB- | denotes | ) |
| T509 | 290-294 | IN | denotes | from |
| T510 | 295-299 | DT | denotes | both |
| T511 | 300-302 | NNP | denotes | CF |
| T512 | 303-306 | CC | denotes | and |
| T513 | 307-314 | JJ | denotes | healthy |
| T514 | 315-322 | NN | denotes | control |
| T515 | 323-331 | NNS | denotes | subjects |
| T516 | 332-340 | VBD | denotes | produced |
| T517 | 341-346 | JJ | denotes | large |
| T518 | 347-354 | NNS | denotes | amounts |
| T519 | 355-357 | IN | denotes | of |
| T520 | 358-363 | NN | denotes | IL-1β |
| T521 | 364-367 | CC | denotes | and |
| T522 | 368-376 | RB | denotes | strongly |
| T523 | 377-388 | VBD | denotes | upregulated |
| T524 | 389-398 | JJ | denotes | caspase-1 |
| T525 | 399-407 | NN | denotes | activity |
| T526 | 408-412 | IN | denotes | upon |
| T527 | 413-425 | JJ | denotes | inflammasome |
| T528 | 426-437 | NN | denotes | stimulation |
| T529 | 437-438 | . | denotes | . |
| T530 | 439-444 | NNS | denotes | PBMCs |
| T531 | 445-449 | IN | denotes | from |
| T532 | 450-452 | NNP | denotes | CF |
| T533 | 453-461 | NNS | denotes | patients |
| T534 | 462-465 | CC | denotes | and |
| T535 | 466-474 | NNS | denotes | controls |
| T536 | 475-484 | VBD | denotes | displayed |
| T537 | 485-492 | JJ | denotes | similar |
| T538 | 493-499 | NNS | denotes | levels |
| T539 | 500-502 | IN | denotes | of |
| T540 | 503-512 | JJ | denotes | caspase-1 |
| T541 | 513-523 | NN | denotes | activation |
| T542 | 524-527 | CC | denotes | and |
| T543 | 528-533 | JJ | denotes | IL-1β |
| T544 | 534-544 | NN | denotes | production |
| T545 | 545-549 | WRB | denotes | when |
| T546 | 550-560 | VBN | denotes | stimulated |
| T547 | 561-565 | IN | denotes | with |
| T548 | 566-578 | JJ | denotes | inflammasome |
| T549 | 579-589 | NNS | denotes | activators |
| T550 | 589-590 | . | denotes | . |
| T551 | 591-595 | DT | denotes | This |
| T552 | 596-601 | JJ | denotes | IL-1β |
| T553 | 602-612 | NN | denotes | production |
| T554 | 613-616 | VBD | denotes | was |
| T555 | 617-626 | JJ | denotes | dependent |
| T556 | 627-629 | IN | denotes | on |
| T557 | 630-635 | JJ | denotes | NF-κB |
| T558 | 636-644 | NN | denotes | activity |
| T559 | 645-648 | CC | denotes | and |
| T560 | 649-654 | MD | denotes | could |
| T561 | 655-657 | VB | denotes | be |
| T562 | 658-666 | VBN | denotes | enhanced |
| T563 | 667-669 | IN | denotes | by |
| T564 | 670-677 | VBG | denotes | priming |
| T565 | 678-682 | IN | denotes | with |
| T566 | 683-686 | NNP | denotes | LPS |
| T567 | 686-687 | . | denotes | . |
| T568 | 688-695 | RB | denotes | Finally |
| T569 | 695-696 | , | denotes | , |
| T570 | 697-705 | NN | denotes | chemical |
| T571 | 706-716 | NN | denotes | inhibition |
| T572 | 717-719 | IN | denotes | of |
| T573 | 720-724 | NNP | denotes | CFTR |
| T574 | 725-733 | NN | denotes | activity |
| T575 | 734-736 | IN | denotes | in |
| T576 | 737-744 | NN | denotes | control |
| T577 | 745-750 | NNS | denotes | PBMCs |
| T578 | 751-754 | CC | denotes | and |
| T579 | 755-760 | CD | denotes | THP-1 |
| T580 | 761-766 | NNS | denotes | cells |
| T581 | 767-770 | VBD | denotes | did |
| T582 | 771-774 | RB | denotes | not |
| T583 | 775-788 | RB | denotes | significantly |
| T584 | 789-794 | VB | denotes | alter |
| T585 | 795-800 | JJ | denotes | IL-1β |
| T586 | 801-803 | CC | denotes | or |
| T587 | 804-808 | JJ | denotes | IL-8 |
| T588 | 809-819 | NN | denotes | production |
| T589 | 820-822 | IN | denotes | in |
| T590 | 823-831 | NN | denotes | response |
| T591 | 832-834 | TO | denotes | to |
| T592 | 835-837 | NNP | denotes | P. |
| T593 | 838-848 | NN | denotes | aeruginosa |
| T594 | 848-849 | . | denotes | . |
| R405 | T467 | T473 | nsubjpass | Results,found |
| R406 | T468 | T471 | nmod | Bronchial,lines |
| R407 | T469 | T471 | amod | epithelial,lines |
| R408 | T470 | T471 | compound | cell,lines |
| R409 | T471 | T473 | nsubjpass | lines,found |
| R410 | T472 | T473 | auxpass | were,found |
| R412 | T474 | T475 | aux | to,produce |
| R413 | T475 | T473 | xcomp | produce,found |
| R414 | T476 | T477 | amod | negligible,amounts |
| R415 | T477 | T475 | dobj | amounts,produce |
| R416 | T478 | T477 | prep | of,amounts |
| R417 | T479 | T478 | pobj | basal,of |
| R418 | T480 | T477 | cc | or,amounts |
| R419 | T481 | T482 | amod | stimulated,IL-1β |
| R420 | T482 | T477 | conj | IL-1β,amounts |
| R421 | T483 | T473 | prep | compared,found |
| R422 | T484 | T483 | prep | to,compared |
| R423 | T485 | T486 | amod | hematopoeitic,cells |
| R424 | T486 | T484 | pobj | cells,to |
| R425 | T487 | T473 | cc | and,found |
| R426 | T488 | T492 | nsubj | they,upregulate |
| R427 | T489 | T492 | aux | did,upregulate |
| R428 | T490 | T492 | neg | not,upregulate |
| R429 | T491 | T492 | advmod | significantly,upregulate |
| R430 | T492 | T473 | conj | upregulate,found |
| R431 | T493 | T494 | amod | caspase-1,activity |
| R432 | T494 | T492 | dobj | activity,upregulate |
| R433 | T495 | T492 | prep | upon,upregulate |
| R434 | T496 | T497 | amod | inflammasome,stimulation |
| R435 | T497 | T495 | pobj | stimulation,upon |
| R437 | T499 | T516 | prep | In,produced |
| R438 | T500 | T499 | pobj | contrast,In |
| R439 | T501 | T516 | punct | ",",produced |
| R440 | T502 | T505 | amod | peripheral,cells |
| R441 | T503 | T504 | compound | blood,mononuclear |
| R442 | T504 | T505 | compound | mononuclear,cells |
| R443 | T505 | T516 | nsubj | cells,produced |
| R444 | T506 | T505 | punct | (,cells |
| R445 | T507 | T505 | appos | PBMCs,cells |
| R446 | T508 | T505 | punct | ),cells |
| R447 | T509 | T505 | prep | from,cells |
| R448 | T510 | T511 | preconj | both,CF |
| R449 | T511 | T509 | pobj | CF,from |
| R450 | T512 | T511 | cc | and,CF |
| R451 | T513 | T515 | amod | healthy,subjects |
| R452 | T514 | T515 | compound | control,subjects |
| R453 | T515 | T511 | conj | subjects,CF |
| R454 | T516 | T516 | ROOT | produced,produced |
| R455 | T517 | T518 | amod | large,amounts |
| R456 | T518 | T516 | dobj | amounts,produced |
| R457 | T519 | T518 | prep | of,amounts |
| R458 | T520 | T519 | pobj | IL-1β,of |
| R459 | T521 | T516 | cc | and,produced |
| R460 | T522 | T523 | advmod | strongly,upregulated |
| R461 | T523 | T516 | conj | upregulated,produced |
| R462 | T524 | T525 | amod | caspase-1,activity |
| R463 | T525 | T523 | dobj | activity,upregulated |
| R464 | T526 | T523 | prep | upon,upregulated |
| R465 | T527 | T528 | amod | inflammasome,stimulation |
| R466 | T528 | T526 | pobj | stimulation,upon |
| R467 | T529 | T516 | punct | .,produced |
| R468 | T530 | T536 | nsubj | PBMCs,displayed |
| R469 | T531 | T530 | prep | from,PBMCs |
| R470 | T532 | T533 | compound | CF,patients |
| R471 | T533 | T531 | pobj | patients,from |
| R472 | T534 | T533 | cc | and,patients |
| R473 | T535 | T533 | conj | controls,patients |
| R474 | T536 | T536 | ROOT | displayed,displayed |
| R475 | T537 | T538 | amod | similar,levels |
| R476 | T538 | T536 | dobj | levels,displayed |
| R477 | T539 | T538 | prep | of,levels |
| R478 | T540 | T541 | amod | caspase-1,activation |
| R479 | T541 | T539 | pobj | activation,of |
| R480 | T542 | T541 | cc | and,activation |
| R481 | T543 | T544 | amod | IL-1β,production |
| R482 | T544 | T541 | conj | production,activation |
| R483 | T545 | T546 | advmod | when,stimulated |
| R484 | T546 | T536 | advcl | stimulated,displayed |
| R485 | T547 | T546 | prep | with,stimulated |
| R486 | T548 | T549 | amod | inflammasome,activators |
| R487 | T549 | T547 | pobj | activators,with |
| R488 | T550 | T536 | punct | .,displayed |
| R489 | T551 | T553 | det | This,production |
| R490 | T552 | T553 | compound | IL-1β,production |
| R491 | T553 | T554 | nsubj | production,was |
| R492 | T554 | T554 | ROOT | was,was |
| R493 | T555 | T554 | acomp | dependent,was |
| R494 | T556 | T555 | prep | on,dependent |
| R495 | T557 | T558 | amod | NF-κB,activity |
| R496 | T558 | T556 | pobj | activity,on |
| R497 | T559 | T554 | cc | and,was |
| R498 | T560 | T562 | aux | could,enhanced |
| R499 | T561 | T562 | auxpass | be,enhanced |
| R500 | T562 | T554 | conj | enhanced,was |
| R501 | T563 | T562 | prep | by,enhanced |
| R502 | T564 | T563 | pcomp | priming,by |
| R503 | T565 | T564 | prep | with,priming |
| R504 | T566 | T565 | pobj | LPS,with |
| R505 | T567 | T554 | punct | .,was |
| R506 | T568 | T584 | advmod | Finally,alter |
| R507 | T569 | T584 | punct | ",",alter |
| R508 | T570 | T571 | compound | chemical,inhibition |
| R509 | T571 | T584 | nsubj | inhibition,alter |
| R510 | T572 | T571 | prep | of,inhibition |
| R511 | T573 | T574 | amod | CFTR,activity |
| R512 | T574 | T572 | pobj | activity,of |
| R513 | T575 | T574 | prep | in,activity |
| R514 | T576 | T575 | pobj | control,in |
| R515 | T577 | T571 | conj | PBMCs,inhibition |
| R516 | T578 | T577 | cc | and,PBMCs |
| R517 | T579 | T580 | nummod | THP-1,cells |
| R518 | T580 | T577 | conj | cells,PBMCs |
| R519 | T581 | T584 | aux | did,alter |
| R520 | T582 | T584 | neg | not,alter |
| R521 | T583 | T584 | advmod | significantly,alter |
| R522 | T584 | T584 | ROOT | alter,alter |
| R523 | T585 | T588 | amod | IL-1β,production |
| R524 | T586 | T585 | cc | or,IL-1β |
| R525 | T587 | T585 | conj | IL-8,IL-1β |
| R526 | T588 | T584 | dobj | production,alter |
| R527 | T589 | T584 | prep | in,alter |
| R528 | T590 | T589 | pobj | response,in |
| R529 | T591 | T590 | prep | to,response |
| R530 | T592 | T593 | compound | P.,aeruginosa |
| R531 | T593 | T591 | pobj | aeruginosa,to |
| R532 | T594 | T584 | punct | .,alter |
pmc-enju-pas
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T174 | 0-7 | NN | denotes | Results |
| T175 | 8-17 | JJ | denotes | Bronchial |
| T176 | 18-28 | JJ | denotes | epithelial |
| T177 | 29-33 | NN | denotes | cell |
| T178 | 34-39 | NN | denotes | lines |
| T179 | 40-44 | VB | denotes | were |
| T180 | 45-50 | VB | denotes | found |
| T181 | 51-53 | TO | denotes | to |
| T182 | 54-61 | VB | denotes | produce |
| T183 | 62-72 | JJ | denotes | negligible |
| T184 | 73-80 | NN | denotes | amounts |
| T185 | 81-83 | IN | denotes | of |
| T186 | 84-89 | JJ | denotes | basal |
| T187 | 90-92 | CC | denotes | or |
| T188 | 93-103 | VB | denotes | stimulated |
| T189 | 104-109 | NN | denotes | IL-1β |
| T190 | 110-118 | VB | denotes | compared |
| T191 | 119-121 | TO | denotes | to |
| T192 | 122-135 | JJ | denotes | hematopoeitic |
| T193 | 136-141 | NN | denotes | cells |
| T194 | 142-145 | CC | denotes | and |
| T195 | 146-150 | PRP | denotes | they |
| T196 | 151-154 | VB | denotes | did |
| T197 | 155-158 | RB | denotes | not |
| T198 | 159-172 | RB | denotes | significantly |
| T199 | 173-183 | VB | denotes | upregulate |
| T200 | 184-193 | NN | denotes | caspase-1 |
| T201 | 194-202 | NN | denotes | activity |
| T202 | 203-207 | IN | denotes | upon |
| T203 | 208-220 | JJ | denotes | inflammasome |
| T204 | 221-232 | NN | denotes | stimulation |
| T205 | 234-236 | IN | denotes | In |
| T206 | 237-245 | NN | denotes | contrast |
| T207 | 245-246 | -COMMA- | denotes | , |
| T208 | 247-257 | JJ | denotes | peripheral |
| T209 | 258-263 | NN | denotes | blood |
| T210 | 264-275 | JJ | denotes | mononuclear |
| T211 | 276-281 | NN | denotes | cells |
| T212 | 282-283 | -LRB- | denotes | ( |
| T213 | 283-288 | NN | denotes | PBMCs |
| T214 | 288-289 | -RRB- | denotes | ) |
| T215 | 290-294 | IN | denotes | from |
| T216 | 295-299 | CC | denotes | both |
| T217 | 300-302 | NN | denotes | CF |
| T218 | 303-306 | CC | denotes | and |
| T219 | 307-314 | JJ | denotes | healthy |
| T220 | 315-322 | NN | denotes | control |
| T221 | 323-331 | NN | denotes | subjects |
| T222 | 332-340 | VB | denotes | produced |
| T223 | 341-346 | JJ | denotes | large |
| T224 | 347-354 | NN | denotes | amounts |
| T225 | 355-357 | IN | denotes | of |
| T226 | 358-363 | NN | denotes | IL-1β |
| T227 | 364-367 | CC | denotes | and |
| T228 | 368-376 | RB | denotes | strongly |
| T229 | 377-388 | VB | denotes | upregulated |
| T230 | 389-398 | NN | denotes | caspase-1 |
| T231 | 399-407 | NN | denotes | activity |
| T232 | 408-412 | IN | denotes | upon |
| T233 | 413-425 | JJ | denotes | inflammasome |
| T234 | 426-437 | NN | denotes | stimulation |
| T235 | 439-444 | NN | denotes | PBMCs |
| T236 | 445-449 | IN | denotes | from |
| T237 | 450-452 | NN | denotes | CF |
| T238 | 453-461 | NN | denotes | patients |
| T239 | 462-465 | CC | denotes | and |
| T240 | 466-474 | NN | denotes | controls |
| T241 | 475-484 | VB | denotes | displayed |
| T242 | 485-492 | JJ | denotes | similar |
| T243 | 493-499 | NN | denotes | levels |
| T244 | 500-502 | IN | denotes | of |
| T245 | 503-512 | NN | denotes | caspase-1 |
| T246 | 513-523 | NN | denotes | activation |
| T247 | 524-527 | CC | denotes | and |
| T248 | 528-533 | NN | denotes | IL-1β |
| T249 | 534-544 | NN | denotes | production |
| T250 | 545-549 | WRB | denotes | when |
| T251 | 550-560 | VB | denotes | stimulated |
| T252 | 561-565 | IN | denotes | with |
| T253 | 566-578 | JJ | denotes | inflammasome |
| T254 | 579-589 | NN | denotes | activators |
| T255 | 591-595 | DT | denotes | This |
| T256 | 596-601 | NN | denotes | IL-1β |
| T257 | 602-612 | NN | denotes | production |
| T258 | 613-616 | VB | denotes | was |
| T259 | 617-626 | JJ | denotes | dependent |
| T260 | 627-629 | IN | denotes | on |
| T261 | 630-635 | NN | denotes | NF-κB |
| T262 | 636-644 | NN | denotes | activity |
| T263 | 645-648 | CC | denotes | and |
| T264 | 649-654 | MD | denotes | could |
| T265 | 655-657 | VB | denotes | be |
| T266 | 658-666 | VB | denotes | enhanced |
| T267 | 667-669 | IN | denotes | by |
| T268 | 670-677 | VB | denotes | priming |
| T269 | 678-682 | IN | denotes | with |
| T270 | 683-686 | NN | denotes | LPS |
| T271 | 688-695 | RB | denotes | Finally |
| T272 | 695-696 | -COMMA- | denotes | , |
| T273 | 697-705 | JJ | denotes | chemical |
| T274 | 706-716 | NN | denotes | inhibition |
| T275 | 717-719 | IN | denotes | of |
| T276 | 720-724 | NN | denotes | CFTR |
| T277 | 725-733 | NN | denotes | activity |
| T278 | 734-736 | IN | denotes | in |
| T279 | 737-744 | NN | denotes | control |
| T280 | 745-750 | NN | denotes | PBMCs |
| T281 | 751-754 | CC | denotes | and |
| T282 | 755-760 | NN | denotes | THP-1 |
| T283 | 761-766 | NN | denotes | cells |
| T284 | 767-770 | VB | denotes | did |
| T285 | 771-774 | RB | denotes | not |
| T286 | 775-788 | RB | denotes | significantly |
| T287 | 789-794 | VB | denotes | alter |
| T288 | 795-800 | NN | denotes | IL-1β |
| T289 | 801-803 | CC | denotes | or |
| T290 | 804-808 | NN | denotes | IL-8 |
| T291 | 809-819 | NN | denotes | production |
| T292 | 820-822 | IN | denotes | in |
| T293 | 823-831 | NN | denotes | response |
| T294 | 832-834 | TO | denotes | to |
| T295 | 835-837 | NNP | denotes | P. |
| T296 | 838-848 | NN | denotes | aeruginosa |
| R125 | T178 | T175 | arg1Of | lines,Bronchial |
| R126 | T178 | T176 | arg1Of | lines,epithelial |
| R127 | T178 | T177 | arg1Of | lines,cell |
| R128 | T178 | T179 | arg1Of | lines,were |
| R129 | T178 | T180 | arg2Of | lines,found |
| R130 | T178 | T182 | arg1Of | lines,produce |
| R131 | T180 | T179 | arg2Of | found,were |
| R132 | T180 | T190 | arg1Of | found,compared |
| R133 | T180 | T194 | arg1Of | found,and |
| R134 | T182 | T180 | arg3Of | produce,found |
| R135 | T182 | T181 | arg1Of | produce,to |
| R136 | T184 | T182 | arg2Of | amounts,produce |
| R137 | T184 | T183 | arg1Of | amounts,negligible |
| R138 | T184 | T185 | arg1Of | amounts,of |
| R139 | T186 | T187 | arg1Of | basal,or |
| R140 | T186 | T188 | arg2Of | basal,stimulated |
| R141 | T189 | T185 | arg2Of | IL-1β,of |
| R142 | T189 | T186 | arg1Of | IL-1β,basal |
| R143 | T191 | T190 | arg2Of | to,compared |
| R144 | T193 | T191 | arg2Of | cells,to |
| R145 | T193 | T192 | arg1Of | cells,hematopoeitic |
| R146 | T195 | T196 | arg1Of | they,did |
| R147 | T195 | T199 | arg1Of | they,upregulate |
| R148 | T199 | T194 | arg2Of | upregulate,and |
| R149 | T199 | T196 | arg2Of | upregulate,did |
| R150 | T199 | T197 | arg1Of | upregulate,not |
| R151 | T199 | T198 | arg1Of | upregulate,significantly |
| R152 | T199 | T202 | arg1Of | upregulate,upon |
| R153 | T201 | T199 | arg2Of | activity,upregulate |
| R154 | T201 | T200 | arg1Of | activity,caspase-1 |
| R155 | T204 | T202 | arg2Of | stimulation,upon |
| R156 | T204 | T203 | arg1Of | stimulation,inflammasome |
| R157 | T206 | T205 | arg2Of | contrast,In |
| R158 | T211 | T208 | arg1Of | cells,peripheral |
| R159 | T211 | T209 | arg1Of | cells,blood |
| R160 | T211 | T210 | arg1Of | cells,mononuclear |
| R161 | T211 | T212 | arg1Of | cells,( |
| R162 | T211 | T215 | arg1Of | cells,from |
| R163 | T211 | T222 | arg1Of | cells,produced |
| R164 | T213 | T212 | arg2Of | PBMCs,( |
| R165 | T214 | T212 | arg3Of | ),( |
| R166 | T221 | T215 | arg2Of | subjects,from |
| R167 | T221 | T216 | arg1Of | subjects,both |
| R168 | T221 | T217 | arg1Of | subjects,CF |
| R169 | T221 | T218 | arg1Of | subjects,and |
| R170 | T221 | T219 | arg1Of | subjects,healthy |
| R171 | T221 | T220 | arg1Of | subjects,control |
| R172 | T222 | T205 | arg1Of | produced,In |
| R173 | T222 | T207 | arg1Of | produced,"," |
| R174 | T224 | T222 | arg2Of | amounts,produced |
| R175 | T224 | T223 | arg1Of | amounts,large |
| R176 | T224 | T225 | arg1Of | amounts,of |
| R177 | T226 | T227 | arg1Of | IL-1β,and |
| R178 | T227 | T225 | arg2Of | and,of |
| R179 | T227 | T232 | arg1Of | and,upon |
| R180 | T229 | T228 | arg1Of | upregulated,strongly |
| R181 | T231 | T227 | arg2Of | activity,and |
| R182 | T231 | T229 | arg2Of | activity,upregulated |
| R183 | T231 | T230 | arg1Of | activity,caspase-1 |
| R184 | T234 | T232 | arg2Of | stimulation,upon |
| R185 | T234 | T233 | arg1Of | stimulation,inflammasome |
| R186 | T235 | T236 | arg1Of | PBMCs,from |
| R187 | T235 | T241 | arg1Of | PBMCs,displayed |
| R188 | T238 | T237 | arg1Of | patients,CF |
| R189 | T238 | T239 | arg1Of | patients,and |
| R190 | T239 | T236 | arg2Of | and,from |
| R191 | T240 | T239 | arg2Of | controls,and |
| R192 | T241 | T250 | arg1Of | displayed,when |
| R193 | T243 | T241 | arg2Of | levels,displayed |
| R194 | T243 | T242 | arg1Of | levels,similar |
| R195 | T243 | T244 | arg1Of | levels,of |
| R196 | T246 | T245 | arg1Of | activation,caspase-1 |
| R197 | T246 | T247 | arg1Of | activation,and |
| R198 | T247 | T244 | arg2Of | and,of |
| R199 | T249 | T247 | arg2Of | production,and |
| R200 | T249 | T248 | arg1Of | production,IL-1β |
| R201 | T251 | T250 | arg2Of | stimulated,when |
| R202 | T251 | T252 | arg1Of | stimulated,with |
| R203 | T254 | T252 | arg2Of | activators,with |
| R204 | T254 | T253 | arg1Of | activators,inflammasome |
| R205 | T257 | T255 | arg1Of | production,This |
| R206 | T257 | T256 | arg1Of | production,IL-1β |
| R207 | T257 | T258 | arg1Of | production,was |
| R208 | T257 | T259 | arg1Of | production,dependent |
| R209 | T257 | T264 | arg1Of | production,could |
| R210 | T257 | T265 | arg1Of | production,be |
| R211 | T257 | T266 | arg2Of | production,enhanced |
| R212 | T258 | T263 | arg1Of | was,and |
| R213 | T259 | T258 | arg2Of | dependent,was |
| R214 | T259 | T260 | arg1Of | dependent,on |
| R215 | T262 | T260 | arg2Of | activity,on |
| R216 | T262 | T261 | arg1Of | activity,NF-κB |
| R217 | T266 | T263 | arg2Of | enhanced,and |
| R218 | T266 | T264 | arg2Of | enhanced,could |
| R219 | T266 | T265 | arg2Of | enhanced,be |
| R220 | T266 | T267 | arg1Of | enhanced,by |
| R221 | T268 | T267 | arg2Of | priming,by |
| R222 | T268 | T269 | arg1Of | priming,with |
| R223 | T270 | T269 | arg2Of | LPS,with |
| R224 | T274 | T273 | arg1Of | inhibition,chemical |
| R225 | T274 | T275 | arg1Of | inhibition,of |
| R226 | T274 | T278 | arg1Of | inhibition,in |
| R227 | T274 | T284 | arg1Of | inhibition,did |
| R228 | T274 | T287 | arg1Of | inhibition,alter |
| R229 | T277 | T275 | arg2Of | activity,of |
| R230 | T277 | T276 | arg1Of | activity,CFTR |
| R231 | T280 | T279 | arg1Of | PBMCs,control |
| R232 | T280 | T281 | arg1Of | PBMCs,and |
| R233 | T281 | T278 | arg2Of | and,in |
| R234 | T283 | T281 | arg2Of | cells,and |
| R235 | T283 | T282 | arg1Of | cells,THP-1 |
| R236 | T287 | T271 | arg1Of | alter,Finally |
| R237 | T287 | T272 | arg1Of | alter,"," |
| R238 | T287 | T284 | arg2Of | alter,did |
| R239 | T287 | T285 | arg1Of | alter,not |
| R240 | T287 | T286 | arg1Of | alter,significantly |
| R241 | T287 | T292 | arg1Of | alter,in |
| R242 | T288 | T289 | arg1Of | IL-1β,or |
| R243 | T290 | T289 | arg2Of | IL-8,or |
| R244 | T291 | T287 | arg2Of | production,alter |
| R245 | T291 | T288 | arg1Of | production,IL-1β |
| R246 | T291 | T290 | arg1Of | production,IL-8 |
| R247 | T293 | T292 | arg2Of | response,in |
| R248 | T293 | T294 | arg1Of | response,to |
| R249 | T296 | T294 | arg2Of | aeruginosa,to |
| R250 | T296 | T295 | arg1Of | aeruginosa,P. |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T79 | 0-7 | Sentence | denotes | Results |
| T80 | 8-233 | Sentence | denotes | Bronchial epithelial cell lines were found to produce negligible amounts of basal or stimulated IL-1β compared to hematopoeitic cells and they did not significantly upregulate caspase-1 activity upon inflammasome stimulation. |
| T81 | 234-438 | Sentence | denotes | In contrast, peripheral blood mononuclear cells (PBMCs) from both CF and healthy control subjects produced large amounts of IL-1β and strongly upregulated caspase-1 activity upon inflammasome stimulation. |
| T82 | 439-590 | Sentence | denotes | PBMCs from CF patients and controls displayed similar levels of caspase-1 activation and IL-1β production when stimulated with inflammasome activators. |
| T83 | 591-687 | Sentence | denotes | This IL-1β production was dependent on NF-κB activity and could be enhanced by priming with LPS. |
| T84 | 688-849 | Sentence | denotes | Finally, chemical inhibition of CFTR activity in control PBMCs and THP-1 cells did not significantly alter IL-1β or IL-8 production in response to P. aeruginosa. |
| T9 | 0-7 | Sentence | denotes | Results |
| T10 | 8-233 | Sentence | denotes | Bronchial epithelial cell lines were found to produce negligible amounts of basal or stimulated IL-1β compared to hematopoeitic cells and they did not significantly upregulate caspase-1 activity upon inflammasome stimulation. |
| T11 | 234-438 | Sentence | denotes | In contrast, peripheral blood mononuclear cells (PBMCs) from both CF and healthy control subjects produced large amounts of IL-1β and strongly upregulated caspase-1 activity upon inflammasome stimulation. |
| T12 | 439-590 | Sentence | denotes | PBMCs from CF patients and controls displayed similar levels of caspase-1 activation and IL-1β production when stimulated with inflammasome activators. |
| T13 | 591-687 | Sentence | denotes | This IL-1β production was dependent on NF-κB activity and could be enhanced by priming with LPS. |
| T14 | 688-849 | Sentence | denotes | Finally, chemical inhibition of CFTR activity in control PBMCs and THP-1 cells did not significantly alter IL-1β or IL-8 production in response to P. aeruginosa. |