PMC:3359311 / 5757-7939
Annnotations
test2
| Id | Subject | Object | Predicate | Lexical cue | Negation | Speculation |
|---|---|---|---|---|---|---|
| T2577 | 31-38 | Gene_expression | denotes | produce | ||
| T2578 | 62-67 | Protein | denotes | IL-1β | true | |
| T2579 | 68-82 | Positive_regulation | denotes | in response to | true | |
| T2580 | 472-482 | Positive_regulation | denotes | contribute | ||
| T2581 | 490-499 | Positive_regulation | denotes | increased | ||
| T2582 | 500-505 | Protein | denotes | IL-1β | true | |
| T2583 | 506-516 | Gene_expression | denotes | production | ||
| T2584 | 690-695 | Protein | denotes | IL-1β | ||
| T2585 | 749-758 | Positive_regulation | denotes | increased | ||
| T2586 | 828-836 | Positive_regulation | denotes | increase | ||
| T2587 | 840-845 | Protein | denotes | IL-1β | ||
| T2588 | 846-856 | Gene_expression | denotes | production | ||
| T2589 | 1048-1053 | Protein | denotes | IL-1β | ||
| T2590 | 1055-1064 | Gene_expression | denotes | producing | ||
| T12791 | 1567-1577 | Positive_regulation | denotes | contribute | true | |
| T12792 | 1581-1586 | Protein | denotes | IL-1β | ||
| T12793 | 1587-1597 | Gene_expression | denotes | production | ||
| T12794 | 1598-1612 | Positive_regulation | denotes | in response to | ||
| T12795 | 1809-1814 | Protein | denotes | IL-1β | ||
| T12796 | 1996-2001 | Protein | denotes | IL-1β | ||
| T12797 | 2011-2021 | Gene_expression | denotes | production | ||
| T12798 | 2050-2059 | Localization | denotes | secretion | ||
| T12799 | 2060-2074 | Positive_regulation | denotes | in response to | ||
| T12800 | 2092-2097 | Protein | denotes | IL-1β | ||
| R2217 | T2577 | T2579 | themeOf | produce,in response to | ||
| R2218 | T2578 | T2577 | themeOf | IL-1β,produce | ||
| R2219 | T2581 | T2580 | themeOf | increased,contribute | ||
| R2220 | T2582 | T2583 | themeOf | IL-1β,production | ||
| R2221 | T2583 | T2581 | themeOf | production,increased | ||
| R2222 | T2584 | T2585 | themeOf | IL-1β,increased | ||
| R2223 | T2587 | T2588 | themeOf | IL-1β,production | ||
| R2224 | T2588 | T2586 | themeOf | production,increase | ||
| R11346 | T12792 | T12793 | themeOf | IL-1β,production | ||
| R11347 | T12793 | T12791 | themeOf | production,contribute | ||
| R11348 | T12794 | T12791 | themeOf | in response to,contribute | ||
| R11349 | T12796 | T12797 | themeOf | IL-1β,production | ||
| R11350 | T12798 | T12799 | themeOf | secretion,in response to | ||
| R11351 | T12800 | T12799 | causeOf | IL-1β,in response to |
bionlp-st-ge-2016-uniprot
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2800 | 62-67 | P01584 | denotes | IL-1β |
| T2801 | 500-505 | P01584 | denotes | IL-1β |
| T2802 | 690-695 | P01584 | denotes | IL-1β |
| T2803 | 840-845 | P01584 | denotes | IL-1β |
| T2804 | 1048-1053 | P01584 | denotes | IL-1β |
| T2805 | 1085-1089 | P10145 | denotes | IL-8 |
| T12933 | 1581-1586 | P01584 | denotes | IL-1β |
| T12934 | 1809-1814 | P01584 | denotes | IL-1β |
| T12935 | 1996-2001 | P01584 | denotes | IL-1β |
| T12936 | 2006-2010 | P10145 | denotes | IL-8 |
| T12937 | 2045-2049 | P10145 | denotes | IL-8 |
| T12938 | 2092-2097 | P01584 | denotes | IL-1β |
bionlp-st-ge-2016-reference
| Id | Subject | Object | Predicate | Lexical cue | Negation | Speculation |
|---|---|---|---|---|---|---|
| T2591 | 31-38 | Gene_expression | denotes | produce | ||
| T2592 | 62-67 | Protein | denotes | IL-1β | ||
| T2593 | 68-82 | Positive_regulation | denotes | in response to | true | |
| T2594 | 472-482 | Positive_regulation | denotes | contribute | true | |
| T2595 | 490-499 | Positive_regulation | denotes | increased | ||
| T2596 | 500-505 | Protein | denotes | IL-1β | ||
| T2597 | 506-516 | Gene_expression | denotes | production | ||
| T2598 | 690-695 | Protein | denotes | IL-1β | ||
| T2599 | 749-758 | Positive_regulation | denotes | increased | true | |
| T2600 | 828-836 | Positive_regulation | denotes | increase | ||
| T2601 | 840-845 | Protein | denotes | IL-1β | ||
| T2602 | 846-856 | Gene_expression | denotes | production | ||
| T2603 | 1048-1053 | Protein | denotes | IL-1β | ||
| T12801 | 1567-1577 | Positive_regulation | denotes | contribute | true | |
| T12802 | 1581-1586 | Protein | denotes | IL-1β | ||
| T12803 | 1587-1597 | Gene_expression | denotes | production | ||
| T12804 | 1598-1612 | Positive_regulation | denotes | in response to | ||
| T12805 | 1809-1814 | Protein | denotes | IL-1β | ||
| T12806 | 1996-2001 | Protein | denotes | IL-1β | ||
| T12807 | 2011-2021 | Gene_expression | denotes | production | ||
| T12808 | 2092-2097 | Protein | denotes | IL-1β | ||
| R2225 | T2591 | T2593 | themeOf | produce,in response to | ||
| R2226 | T2592 | T2591 | themeOf | IL-1β,produce | ||
| R2227 | T2595 | T2594 | themeOf | increased,contribute | ||
| R2228 | T2596 | T2597 | themeOf | IL-1β,production | ||
| R2229 | T2597 | T2595 | themeOf | production,increased | ||
| R2230 | T2598 | T2599 | themeOf | IL-1β,increased | ||
| R2231 | T2601 | T2602 | themeOf | IL-1β,production | ||
| R2232 | T2602 | T2600 | themeOf | production,increase | ||
| R11352 | T12802 | T12803 | themeOf | IL-1β,production | ||
| R11353 | T12803 | T12804 | themeOf | production,in response to | ||
| R11354 | T12804 | T12801 | themeOf | in response to,contribute | ||
| R11355 | T12806 | T12807 | themeOf | IL-1β,production |
bionlp-st-ge-2016-reference-tees
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3057 | 62-67 | Protein | denotes | IL-1β |
| T3058 | 31-38 | Gene_expression | denotes | produce |
| T3059 | 500-505 | Protein | denotes | IL-1β |
| T3060 | 623-657 | Protein | denotes | inducers P. aeruginosa strain PAO1 |
| T3061 | 659-663 | Protein | denotes | PAO1 |
| T3062 | 506-516 | Gene_expression | denotes | production |
| T3063 | 490-499 | Positive_regulation | denotes | increased |
| T3064 | 690-695 | Protein | denotes | IL-1β |
| T3065 | 840-845 | Protein | denotes | IL-1β |
| T3066 | 749-758 | Positive_regulation | denotes | increased |
| T3067 | 846-856 | Gene_expression | denotes | production |
| T3068 | 828-836 | Positive_regulation | denotes | increase |
| T3069 | 1036-1053 | Protein | denotes | recombinant IL-1β |
| T3070 | 1085-1089 | Protein | denotes | IL-8 |
| T3071 | 1091-1094 | Protein | denotes | Fig |
| T3072 | 1055-1064 | Gene_expression | denotes | producing |
| T3073 | 1055-1064 | Gene_expression | denotes | producing |
| T12782 | 1311-1325 | Protein | denotes | THP-1 reporter |
| T13106 | 1581-1586 | Protein | denotes | IL-1β |
| T13107 | 1587-1597 | Gene_expression | denotes | production |
| T13108 | 1809-1814 | Protein | denotes | IL-1β |
| T13109 | 1996-2001 | Protein | denotes | IL-1β |
| T13110 | 2006-2010 | Protein | denotes | IL-8 |
| T13111 | 2011-2021 | Gene_expression | denotes | production |
| T13112 | 2011-2021 | Gene_expression | denotes | production |
| T13113 | 2092-2097 | Protein | denotes | IL-1β |
| R2651 | T3057 | T3058 | themeOf | IL-1β,produce |
| R2652 | T3059 | T3062 | themeOf | IL-1β,production |
| R2653 | T3062 | T3063 | themeOf | production,increased |
| R2654 | T3064 | T3066 | themeOf | IL-1β,increased |
| R2655 | T3065 | T3067 | themeOf | IL-1β,production |
| R2656 | T3067 | T3068 | themeOf | production,increase |
| R2657 | T3070 | T3072 | themeOf | IL-8,producing |
| R2658 | T3071 | T3073 | themeOf | Fig,producing |
| R11615 | T13106 | T13107 | themeOf | IL-1β,production |
| R11616 | T13109 | T13111 | themeOf | IL-1β,production |
| R11617 | T13110 | T13112 | themeOf | IL-8,production |
events-check-again
| Id | Subject | Object | Predicate | Lexical cue | Negation | Speculation |
|---|---|---|---|---|---|---|
| T3044 | 31-38 | Gene_expression | denotes | produce | ||
| T3045 | 62-67 | Protein | denotes | IL-1β | ||
| T3046 | 68-82 | Positive_regulation | denotes | in response to | true | |
| T3047 | 472-482 | Positive_regulation | denotes | contribute | true | |
| T3048 | 490-499 | Positive_regulation | denotes | increased | ||
| T3049 | 500-505 | Protein | denotes | IL-1β | ||
| T3050 | 506-516 | Gene_expression | denotes | production | ||
| T3051 | 690-695 | Protein | denotes | IL-1β | ||
| T3052 | 749-758 | Positive_regulation | denotes | increased | true | |
| T3053 | 828-836 | Positive_regulation | denotes | increase | ||
| T3054 | 840-845 | Protein | denotes | IL-1β | ||
| T3055 | 846-856 | Gene_expression | denotes | production | ||
| T3056 | 1048-1053 | Protein | denotes | IL-1β | ||
| T13098 | 1567-1577 | Positive_regulation | denotes | contribute | true | |
| T13099 | 1581-1586 | Protein | denotes | IL-1β | ||
| T13100 | 1587-1597 | Gene_expression | denotes | production | ||
| T13101 | 1598-1612 | Positive_regulation | denotes | in response to | ||
| T13102 | 1809-1814 | Protein | denotes | IL-1β | ||
| T13103 | 1996-2001 | Protein | denotes | IL-1β | ||
| T13104 | 2011-2021 | Gene_expression | denotes | production | ||
| T13105 | 2092-2097 | Protein | denotes | IL-1β | ||
| R2643 | T3044 | T3046 | themeOf | produce,in response to | ||
| R2644 | T3045 | T3044 | themeOf | IL-1β,produce | ||
| R2645 | T3048 | T3047 | themeOf | increased,contribute | ||
| R2646 | T3049 | T3050 | themeOf | IL-1β,production | ||
| R2647 | T3050 | T3048 | themeOf | production,increased | ||
| R2648 | T3051 | T3052 | themeOf | IL-1β,increased | ||
| R2649 | T3054 | T3055 | themeOf | IL-1β,production | ||
| R2650 | T3055 | T3053 | themeOf | production,increase | ||
| R11611 | T13099 | T13100 | themeOf | IL-1β,production | ||
| R11612 | T13100 | T13101 | themeOf | production,in response to | ||
| R11613 | T13101 | T13098 | themeOf | in response to,contribute | ||
| R11614 | T13103 | T13104 | themeOf | IL-1β,production |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3011 | 18-23 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T3012 | 296-301 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T3013 | 466-471 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T3014 | 891-896 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T3015 | 922-927 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T3016 | 968-973 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T12781 | 1155-1159 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | Cell |
| T13078 | 1540-1545 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T13079 | 1741-1746 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T13080 | 1953-1957 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | Cell |
GO-MF
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3017 | 1085-1089 | http://purl.obolibrary.org/obo/GO_0005153 | denotes | IL-8 |
| T13077 | 2045-2049 | http://purl.obolibrary.org/obo/GO_0005153 | denotes | IL-8 |
| T13081 | 2006-2010 | http://purl.obolibrary.org/obo/GO_0005153 | denotes | IL-8 |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3010 | 404-421 | http://purl.obolibrary.org/obo/GO_0034097 | denotes | cytokine response |
| T13072 | 2006-2021 | http://purl.obolibrary.org/obo/GO_0032677 | denotes | IL-8 production |
| T13073 | 2006-2021 | http://purl.obolibrary.org/obo/GO_0032637 | denotes | IL-8 production |
| T13074 | 2045-2059 | http://purl.obolibrary.org/obo/GO_0072606 | denotes | IL-8 secretion |
| T13075 | 2045-2059 | http://purl.obolibrary.org/obo/GO_2000482 | denotes | IL-8 secretion |
| T13076 | 2050-2059 | http://purl.obolibrary.org/obo/GO_0046903 | denotes | secretion |
bionlp-st-ge-2016-spacy-parsed
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2806 | 0-6 | NNP | denotes | Airway |
| T2807 | 7-17 | JJ | denotes | epithelial |
| T2808 | 18-23 | NNS | denotes | cells |
| T2809 | 24-26 | VBP | denotes | do |
| T2810 | 27-30 | RB | denotes | not |
| T2811 | 31-38 | VB | denotes | produce |
| T2812 | 39-50 | JJ | denotes | significant |
| T2813 | 51-58 | NNS | denotes | amounts |
| T2814 | 59-61 | IN | denotes | of |
| T2815 | 62-67 | NN | denotes | IL-1β |
| T2816 | 68-70 | IN | denotes | in |
| T2817 | 71-79 | NN | denotes | response |
| T2818 | 80-82 | TO | denotes | to |
| T2819 | 83-95 | JJ | denotes | inflammasome |
| T2820 | 96-107 | NN | denotes | stimulation |
| T2821 | 108-111 | DT | denotes | The |
| T2822 | 112-125 | NNS | denotes | inflammasomes |
| T2823 | 126-129 | CC | denotes | and |
| T2824 | 130-135 | PRP$ | denotes | their |
| T2825 | 136-146 | JJ | denotes | respective |
| T2826 | 147-157 | NNS | denotes | activators |
| T2827 | 158-166 | VBD | denotes | examined |
| T2828 | 167-169 | IN | denotes | in |
| T2829 | 170-174 | DT | denotes | this |
| T2830 | 175-180 | NN | denotes | study |
| T2831 | 181-184 | VBP | denotes | are |
| T2832 | 185-191 | VBN | denotes | listed |
| T2833 | 192-194 | IN | denotes | in |
| T2834 | 195-200 | NNP | denotes | Table |
| T2835 | 201-202 | CD | denotes | 1 |
| T2836 | 202-203 | . | denotes | . |
| T2837 | 204-209 | NNS | denotes | Cells |
| T2838 | 210-214 | VBD | denotes | were |
| T2839 | 215-225 | VBN | denotes | stimulated |
| T2840 | 226-228 | IN | denotes | in |
| T2841 | 229-239 | NN | denotes | accordance |
| T2842 | 240-244 | IN | denotes | with |
| T2843 | 245-248 | DT | denotes | the |
| T2844 | 249-257 | NN | denotes | schedule |
| T2845 | 258-260 | IN | denotes | in |
| T2846 | 261-267 | NN | denotes | Figure |
| T2847 | 268-269 | CD | denotes | 1 |
| T2848 | 269-270 | . | denotes | . |
| T2849 | 271-273 | IN | denotes | In |
| T2850 | 274-276 | NNP | denotes | CF |
| T2851 | 276-277 | , | denotes | , |
| T2852 | 278-284 | NN | denotes | airway |
| T2853 | 285-295 | JJ | denotes | epithelial |
| T2854 | 296-301 | NNS | denotes | cells |
| T2855 | 302-306 | VBP | denotes | have |
| T2856 | 307-311 | VBN | denotes | been |
| T2857 | 312-317 | VBN | denotes | shown |
| T2858 | 318-320 | TO | denotes | to |
| T2859 | 321-328 | VB | denotes | possess |
| T2860 | 329-330 | DT | denotes | a |
| T2861 | 331-349 | JJ | denotes | hyper-inflammatory |
| T2862 | 350-359 | NN | denotes | phenotype |
| T2863 | 360-363 | CC | denotes | and |
| T2864 | 364-371 | VBP | denotes | produce |
| T2865 | 372-374 | DT | denotes | an |
| T2866 | 375-386 | JJ | denotes | exaggerated |
| T2867 | 387-403 | JJ | denotes | pro-inflammatory |
| T2868 | 404-412 | NN | denotes | cytokine |
| T2869 | 413-421 | NN | denotes | response |
| T2870 | 422-423 | NNP | denotes | [ |
| T2871 | 423-424 | CD | denotes | 4 |
| T2872 | 424-425 | NNP | denotes | ] |
| T2873 | 425-426 | , | denotes | , |
| T2874 | 427-428 | NNP | denotes | [ |
| T2875 | 428-429 | CD | denotes | 5 |
| T2876 | 429-430 | NNP | denotes | ] |
| T2877 | 430-431 | . | denotes | . |
| T2878 | 432-434 | TO | denotes | To |
| T2879 | 435-444 | VB | denotes | determine |
| T2880 | 445-447 | IN | denotes | if |
| T2881 | 448-454 | NN | denotes | airway |
| T2882 | 455-465 | JJ | denotes | epithelial |
| T2883 | 466-471 | NNS | denotes | cells |
| T2884 | 472-482 | VBP | denotes | contribute |
| T2885 | 483-485 | TO | denotes | to |
| T2886 | 486-489 | DT | denotes | the |
| T2887 | 490-499 | VBN | denotes | increased |
| T2888 | 500-505 | NN | denotes | IL-1β |
| T2889 | 506-516 | NN | denotes | production |
| T2890 | 517-519 | IN | denotes | in |
| T2891 | 520-528 | NNS | denotes | patients |
| T2892 | 529-533 | IN | denotes | with |
| T2893 | 534-536 | NNP | denotes | CF |
| T2894 | 536-537 | , | denotes | , |
| T2895 | 538-540 | NNP | denotes | CF |
| T2896 | 541-544 | CC | denotes | and |
| T2897 | 545-552 | VB | denotes | control |
| T2898 | 553-562 | JJ | denotes | bronchial |
| T2899 | 563-573 | JJ | denotes | epithelial |
| T2900 | 574-578 | NN | denotes | cell |
| T2901 | 579-584 | NNS | denotes | lines |
| T2902 | 585-589 | VBD | denotes | were |
| T2903 | 590-600 | VBN | denotes | stimulated |
| T2904 | 601-605 | IN | denotes | with |
| T2905 | 606-609 | DT | denotes | the |
| T2906 | 610-622 | JJ | denotes | inflammasome |
| T2907 | 623-631 | NNS | denotes | inducers |
| T2908 | 632-634 | NNP | denotes | P. |
| T2909 | 635-645 | NN | denotes | aeruginosa |
| T2910 | 646-652 | NN | denotes | strain |
| T2911 | 653-657 | NNP | denotes | PAO1 |
| T2912 | 658-659 | -LRB- | denotes | ( |
| T2913 | 659-663 | NNP | denotes | PAO1 |
| T2914 | 663-664 | -RRB- | denotes | ) |
| T2915 | 665-668 | CC | denotes | and |
| T2916 | 669-672 | NNP | denotes | LPS |
| T2917 | 673-681 | VBD | denotes | followed |
| T2918 | 682-684 | IN | denotes | by |
| T2919 | 685-688 | NNP | denotes | ATP |
| T2920 | 688-689 | . | denotes | . |
| T2921 | 690-695 | JJ | denotes | IL-1β |
| T2922 | 696-702 | NNS | denotes | levels |
| T2923 | 703-705 | IN | denotes | in |
| T2924 | 706-710 | NN | denotes | cell |
| T2925 | 711-718 | NN | denotes | culture |
| T2926 | 719-731 | NNS | denotes | supernatants |
| T2927 | 732-736 | VBD | denotes | were |
| T2928 | 737-740 | RB | denotes | not |
| T2929 | 741-748 | RB | denotes | greatly |
| T2930 | 749-758 | VBN | denotes | increased |
| T2931 | 759-761 | IN | denotes | in |
| T2932 | 762-768 | CC | denotes | either |
| T2933 | 769-772 | DT | denotes | the |
| T2934 | 773-775 | NNP | denotes | CF |
| T2935 | 776-778 | CC | denotes | or |
| T2936 | 779-786 | VB | denotes | control |
| T2937 | 787-791 | NN | denotes | cell |
| T2938 | 792-797 | NNS | denotes | lines |
| T2939 | 798-799 | -LRB- | denotes | ( |
| T2940 | 799-803 | NNP | denotes | Fig. |
| T2941 | 804-806 | CD | denotes | 2a |
| T2942 | 807-808 | LS | denotes | d |
| T2943 | 808-809 | -RRB- | denotes | ) |
| T2944 | 809-810 | , | denotes | , |
| T2945 | 811-819 | IN | denotes | although |
| T2946 | 820-821 | DT | denotes | a |
| T2947 | 822-827 | JJ | denotes | small |
| T2948 | 828-836 | NN | denotes | increase |
| T2949 | 837-839 | IN | denotes | in |
| T2950 | 840-845 | JJ | denotes | IL-1β |
| T2951 | 846-856 | NN | denotes | production |
| T2952 | 857-860 | VBD | denotes | was |
| T2953 | 861-869 | VBN | denotes | detected |
| T2954 | 870-872 | IN | denotes | in |
| T2955 | 873-879 | NN | denotes | NuLi-1 |
| T2956 | 880-883 | CC | denotes | and |
| T2957 | 884-890 | NN | denotes | CuFi-1 |
| T2958 | 891-896 | NNS | denotes | cells |
| T2959 | 896-897 | , | denotes | , |
| T2960 | 898-901 | CC | denotes | but |
| T2961 | 902-905 | RB | denotes | not |
| T2962 | 906-908 | IN | denotes | in |
| T2963 | 909-911 | CD | denotes | S9 |
| T2964 | 912-915 | CC | denotes | and |
| T2965 | 916-921 | CD | denotes | IB3-1 |
| T2966 | 922-927 | NNS | denotes | cells |
| T2967 | 927-928 | , | denotes | , |
| T2968 | 929-931 | IN | denotes | by |
| T2969 | 932-934 | CD | denotes | 24 |
| T2970 | 935-940 | NNS | denotes | hours |
| T2971 | 940-941 | . | denotes | . |
| T2972 | 942-944 | IN | denotes | In |
| T2973 | 945-953 | NN | denotes | contrast |
| T2974 | 953-954 | , | denotes | , |
| T2975 | 955-960 | DT | denotes | these |
| T2976 | 961-967 | NN | denotes | airway |
| T2977 | 968-973 | NNS | denotes | cells |
| T2978 | 974-978 | VBD | denotes | were |
| T2979 | 979-985 | RB | denotes | highly |
| T2980 | 986-996 | JJ | denotes | responsive |
| T2981 | 997-999 | TO | denotes | to |
| T2982 | 1000-1005 | JJ | denotes | other |
| T2983 | 1006-1018 | JJ | denotes | inflammatory |
| T2984 | 1019-1026 | NNS | denotes | stimuli |
| T2985 | 1026-1027 | , | denotes | , |
| T2986 | 1028-1032 | JJ | denotes | such |
| T2987 | 1033-1035 | IN | denotes | as |
| T2988 | 1036-1047 | JJ | denotes | recombinant |
| T2989 | 1048-1053 | NNP | denotes | IL-1β |
| T2990 | 1053-1054 | , | denotes | , |
| T2991 | 1055-1064 | VBG | denotes | producing |
| T2992 | 1065-1070 | JJ | denotes | large |
| T2993 | 1071-1081 | NNS | denotes | quantities |
| T2994 | 1082-1084 | IN | denotes | of |
| T2995 | 1085-1089 | NN | denotes | IL-8 |
| T2996 | 1090-1091 | -LRB- | denotes | ( |
| T2997 | 1091-1095 | NNP | denotes | Fig. |
| T2998 | 1096-1098 | CD | denotes | 2a |
| T2999 | 1099-1100 | LS | denotes | d |
| T3000 | 1101-1108 | NNS | denotes | inserts |
| T3001 | 1108-1109 | -RRB- | denotes | ) |
| T3002 | 1109-1110 | . | denotes | . |
| T12728 | 1155-1159 | NNP | denotes | Cell |
| T12729 | 1160-1171 | NN | denotes | stimulation |
| T12730 | 1172-1175 | CC | denotes | and |
| T12731 | 1176-1185 | NN | denotes | inhibitor |
| T12732 | 1186-1194 | NN | denotes | schedule |
| T12733 | 1194-1195 | . | denotes | . |
| T12734 | 1196-1204 | NN | denotes | Schedule |
| T12735 | 1205-1213 | VBZ | denotes | outlines |
| T12736 | 1214-1217 | DT | denotes | the |
| T12737 | 1218-1224 | NN | denotes | timing |
| T12738 | 1225-1227 | IN | denotes | of |
| T12739 | 1228-1237 | NN | denotes | inhibitor |
| T12740 | 1238-1246 | NN | denotes | addition |
| T12741 | 1247-1250 | CC | denotes | and |
| T12742 | 1251-1258 | NN | denotes | priming |
| T12743 | 1259-1261 | IN | denotes | in |
| T12744 | 1262-1270 | NN | denotes | relation |
| T12745 | 1271-1273 | TO | denotes | to |
| T12746 | 1274-1286 | JJ | denotes | inflammasome |
| T12747 | 1287-1298 | NN | denotes | stimulation |
| T12748 | 1299-1300 | -LRB- | denotes | ( |
| T12749 | 1300-1301 | FW | denotes | t |
| T12750 | 1302-1303 | SYM | denotes | = |
| T12751 | 1304-1305 | CD | denotes | 0 |
| T12752 | 1305-1306 | -RRB- | denotes | ) |
| T12753 | 1307-1310 | IN | denotes | for |
| T12754 | 1311-1316 | CD | denotes | THP-1 |
| T12755 | 1317-1325 | NN | denotes | reporter |
| T12756 | 1326-1329 | CC | denotes | and |
| T12757 | 1330-1334 | NNP | denotes | PBMC |
| T12758 | 1335-1343 | NN | denotes | cytokine |
| T12759 | 1344-1358 | NN | denotes | quantification |
| T12760 | 1359-1370 | NNS | denotes | experiments |
| T12761 | 1370-1371 | . | denotes | . |
| T12762 | 1372-1381 | NNP | denotes | Inhibitor |
| T12763 | 1382-1392 | NNS | denotes | treatments |
| T12764 | 1393-1396 | CC | denotes | and |
| T12765 | 1397-1409 | NNS | denotes | stimulations |
| T12766 | 1410-1414 | VBD | denotes | were |
| T12767 | 1415-1422 | VBN | denotes | carried |
| T12768 | 1423-1426 | RP | denotes | out |
| T12769 | 1427-1429 | IN | denotes | as |
| T12770 | 1430-1439 | VBN | denotes | described |
| T12771 | 1440-1442 | IN | denotes | in |
| T12772 | 1443-1446 | DT | denotes | the |
| T12773 | 1447-1456 | NNPS | denotes | Materials |
| T12774 | 1457-1460 | CC | denotes | and |
| T12775 | 1461-1468 | NNPS | denotes | Methods |
| T12776 | 1469-1476 | NN | denotes | section |
| T12777 | 1476-1477 | . | denotes | . |
| T12939 | 1522-1528 | NNP | denotes | Airway |
| T12940 | 1529-1539 | JJ | denotes | epithelial |
| T12941 | 1540-1545 | NNS | denotes | cells |
| T12942 | 1546-1548 | VBP | denotes | do |
| T12943 | 1549-1552 | RB | denotes | not |
| T12944 | 1553-1566 | RB | denotes | significantly |
| T12945 | 1567-1577 | VB | denotes | contribute |
| T12946 | 1578-1580 | TO | denotes | to |
| T12947 | 1581-1586 | JJ | denotes | IL-1β |
| T12948 | 1587-1597 | NN | denotes | production |
| T12949 | 1598-1600 | IN | denotes | in |
| T12950 | 1601-1609 | NN | denotes | response |
| T12951 | 1610-1612 | TO | denotes | to |
| T12952 | 1613-1625 | JJ | denotes | inflammasome |
| T12953 | 1626-1633 | NNS | denotes | stimuli |
| T12954 | 1633-1634 | . | denotes | . |
| T12955 | 1635-1642 | NNP | denotes | Control |
| T12956 | 1643-1647 | NN | denotes | cell |
| T12957 | 1648-1653 | NNS | denotes | lines |
| T12958 | 1654-1655 | -LRB- | denotes | ( |
| T12959 | 1655-1656 | -LRB- | denotes | ( |
| T12960 | 1656-1657 | NNP | denotes | A |
| T12961 | 1657-1658 | -RRB- | denotes | ) |
| T12962 | 1659-1661 | CD | denotes | S9 |
| T12963 | 1661-1662 | , | denotes | , |
| T12964 | 1663-1664 | -LRB- | denotes | ( |
| T12965 | 1664-1665 | NNP | denotes | C |
| T12966 | 1665-1666 | -RRB- | denotes | ) |
| T12967 | 1667-1673 | NN | denotes | NuLi-1 |
| T12968 | 1673-1674 | -RRB- | denotes | ) |
| T12969 | 1675-1678 | CC | denotes | and |
| T12970 | 1679-1684 | PRP$ | denotes | their |
| T12971 | 1685-1698 | JJ | denotes | corresponding |
| T12972 | 1699-1701 | NNP | denotes | CF |
| T12973 | 1702-1706 | NN | denotes | cell |
| T12974 | 1707-1712 | NNS | denotes | lines |
| T12975 | 1713-1714 | -LRB- | denotes | ( |
| T12976 | 1714-1715 | -LRB- | denotes | ( |
| T12977 | 1715-1716 | NNP | denotes | B |
| T12978 | 1716-1717 | -RRB- | denotes | ) |
| T12979 | 1718-1723 | NNP | denotes | IB3-1 |
| T12980 | 1723-1724 | , | denotes | , |
| T12981 | 1725-1728 | CC | denotes | and |
| T12982 | 1729-1730 | -LRB- | denotes | ( |
| T12983 | 1730-1731 | NNP | denotes | D |
| T12984 | 1731-1732 | -RRB- | denotes | ) |
| T12985 | 1733-1739 | NN | denotes | CuFi-1 |
| T12986 | 1739-1740 | -RRB- | denotes | ) |
| T12987 | 1741-1746 | NNS | denotes | cells |
| T12988 | 1747-1751 | VBD | denotes | were |
| T12989 | 1752-1762 | VBN | denotes | stimulated |
| T12990 | 1763-1767 | IN | denotes | with |
| T12991 | 1768-1770 | NNP | denotes | P. |
| T12992 | 1771-1781 | NN | denotes | aeruginosa |
| T12993 | 1782-1783 | -LRB- | denotes | ( |
| T12994 | 1783-1786 | NNP | denotes | MOI |
| T12995 | 1787-1788 | SYM | denotes | = |
| T12996 | 1789-1791 | CD | denotes | 10 |
| T12997 | 1791-1792 | -RRB- | denotes | ) |
| T12998 | 1792-1793 | , | denotes | , |
| T12999 | 1794-1797 | NNP | denotes | ATP |
| T13000 | 1798-1799 | -LRB- | denotes | ( |
| T13001 | 1799-1800 | CD | denotes | 5 |
| T13002 | 1801-1803 | NNP | denotes | mM |
| T13003 | 1803-1804 | -RRB- | denotes | ) |
| T13004 | 1804-1805 | , | denotes | , |
| T13005 | 1806-1808 | CC | denotes | or |
| T13006 | 1809-1814 | NN | denotes | IL-1β |
| T13007 | 1815-1816 | -LRB- | denotes | ( |
| T13008 | 1816-1818 | CD | denotes | 10 |
| T13009 | 1819-1824 | NN | denotes | ng/ml |
| T13010 | 1824-1825 | -RRB- | denotes | ) |
| T13011 | 1825-1826 | , | denotes | , |
| T13012 | 1827-1830 | IN | denotes | for |
| T13013 | 1831-1834 | DT | denotes | the |
| T13014 | 1835-1844 | JJ | denotes | indicated |
| T13015 | 1845-1850 | NNS | denotes | times |
| T13016 | 1851-1852 | -LRB- | denotes | ( |
| T13017 | 1852-1853 | FW | denotes | n |
| T13018 | 1854-1855 | SYM | denotes | = |
| T13019 | 1856-1857 | CD | denotes | 3 |
| T13020 | 1858-1868 | JJ | denotes | individual |
| T13021 | 1869-1880 | NNS | denotes | experiments |
| T13022 | 1880-1881 | -RRB- | denotes | ) |
| T13023 | 1881-1882 | . | denotes | . |
| T13024 | 1883-1888 | NNS | denotes | Cells |
| T13025 | 1889-1893 | VBD | denotes | were |
| T13026 | 1894-1900 | VBN | denotes | primed |
| T13027 | 1901-1905 | IN | denotes | with |
| T13028 | 1906-1909 | NNP | denotes | LPS |
| T13029 | 1910-1911 | -LRB- | denotes | ( |
| T13030 | 1911-1914 | CD | denotes | 100 |
| T13031 | 1915-1920 | NN | denotes | ng/ml |
| T13032 | 1920-1921 | -RRB- | denotes | ) |
| T13033 | 1922-1925 | IN | denotes | for |
| T13034 | 1926-1927 | CD | denotes | 4 |
| T13035 | 1928-1933 | NNS | denotes | hours |
| T13036 | 1934-1939 | WRB | denotes | where |
| T13037 | 1940-1951 | JJ | denotes | appropriate |
| T13038 | 1951-1952 | . | denotes | . |
| T13039 | 1953-1957 | NNP | denotes | Cell |
| T13040 | 1958-1965 | NN | denotes | culture |
| T13041 | 1966-1978 | NNS | denotes | supernatants |
| T13042 | 1979-1983 | VBD | denotes | were |
| T13043 | 1984-1991 | VBN | denotes | assayed |
| T13044 | 1992-1995 | IN | denotes | for |
| T13045 | 1996-2001 | JJ | denotes | IL-1β |
| T13046 | 2002-2005 | CC | denotes | and |
| T13047 | 2006-2010 | JJ | denotes | IL-8 |
| T13048 | 2011-2021 | NN | denotes | production |
| T13049 | 2022-2024 | IN | denotes | by |
| T13050 | 2025-2030 | NNP | denotes | ELISA |
| T13051 | 2030-2031 | . | denotes | . |
| T13052 | 2032-2038 | VB | denotes | Insert |
| T13053 | 2039-2044 | NNS | denotes | shows |
| T13054 | 2045-2049 | JJ | denotes | IL-8 |
| T13055 | 2050-2059 | NN | denotes | secretion |
| T13056 | 2060-2062 | IN | denotes | in |
| T13057 | 2063-2071 | NN | denotes | response |
| T13058 | 2072-2074 | TO | denotes | to |
| T13059 | 2075-2086 | NN | denotes | stimulation |
| T13060 | 2087-2091 | IN | denotes | with |
| T13061 | 2092-2097 | JJ | denotes | IL-1β |
| T13062 | 2098-2099 | -LRB- | denotes | ( |
| T13063 | 2099-2101 | CD | denotes | 10 |
| T13064 | 2102-2107 | NN | denotes | ng/ml |
| T13065 | 2107-2108 | -RRB- | denotes | ) |
| T13066 | 2108-2109 | . | denotes | . |
| T15016 | 2153-2165 | NNP | denotes | Inflammasome |
| T15017 | 2166-2176 | NNP | denotes | Activators |
| T15018 | 2176-2177 | . | denotes | . |
| R2430 | T2806 | T2808 | nmod | Airway,cells |
| R2431 | T2807 | T2808 | amod | epithelial,cells |
| R2432 | T2808 | T2811 | nsubj | cells,produce |
| R2433 | T2809 | T2811 | aux | do,produce |
| R2434 | T2810 | T2811 | neg | not,produce |
| R2435 | T2811 | T2811 | ROOT | produce,produce |
| R2436 | T2812 | T2813 | amod | significant,amounts |
| R2437 | T2813 | T2811 | dobj | amounts,produce |
| R2438 | T2814 | T2813 | prep | of,amounts |
| R2439 | T2815 | T2814 | pobj | IL-1β,of |
| R2440 | T2816 | T2811 | prep | in,produce |
| R2441 | T2817 | T2816 | pobj | response,in |
| R2442 | T2818 | T2817 | prep | to,response |
| R2443 | T2819 | T2820 | amod | inflammasome,stimulation |
| R2444 | T2820 | T2818 | pobj | stimulation,to |
| R2445 | T2821 | T2822 | det | The,inflammasomes |
| R2446 | T2822 | T2827 | nsubj | inflammasomes,examined |
| R2447 | T2823 | T2822 | cc | and,inflammasomes |
| R2448 | T2824 | T2826 | poss | their,activators |
| R2449 | T2825 | T2826 | amod | respective,activators |
| R2450 | T2826 | T2822 | conj | activators,inflammasomes |
| R2451 | T2827 | T2811 | conj | examined,produce |
| R2452 | T2828 | T2827 | prep | in,examined |
| R2453 | T2829 | T2830 | det | this,study |
| R2454 | T2830 | T2828 | pobj | study,in |
| R2455 | T2831 | T2832 | auxpass | are,listed |
| R2456 | T2832 | T2827 | conj | listed,examined |
| R2457 | T2833 | T2832 | prep | in,listed |
| R2458 | T2834 | T2833 | pobj | Table,in |
| R2459 | T2835 | T2834 | nummod | 1,Table |
| R2460 | T2836 | T2827 | punct | .,examined |
| R2461 | T2837 | T2839 | nsubjpass | Cells,stimulated |
| R2462 | T2838 | T2839 | auxpass | were,stimulated |
| R2463 | T2839 | T2839 | ROOT | stimulated,stimulated |
| R2464 | T2840 | T2839 | prep | in,stimulated |
| R2465 | T2841 | T2840 | pobj | accordance,in |
| R2466 | T2842 | T2841 | prep | with,accordance |
| R2467 | T2843 | T2844 | det | the,schedule |
| R2468 | T2844 | T2842 | pobj | schedule,with |
| R2469 | T2845 | T2844 | prep | in,schedule |
| R2470 | T2846 | T2845 | pobj | Figure,in |
| R2471 | T2847 | T2846 | nummod | 1,Figure |
| R2472 | T2848 | T2839 | punct | .,stimulated |
| R2473 | T2849 | T2857 | prep | In,shown |
| R2474 | T2850 | T2849 | pobj | CF,In |
| R2475 | T2851 | T2857 | punct | ",",shown |
| R2476 | T2852 | T2854 | amod | airway,cells |
| R2477 | T2853 | T2854 | amod | epithelial,cells |
| R2478 | T2854 | T2857 | nsubjpass | cells,shown |
| R2479 | T2855 | T2857 | aux | have,shown |
| R2480 | T2856 | T2857 | auxpass | been,shown |
| R2481 | T2857 | T2857 | ROOT | shown,shown |
| R2482 | T2858 | T2859 | aux | to,possess |
| R2483 | T2859 | T2857 | xcomp | possess,shown |
| R2484 | T2860 | T2862 | det | a,phenotype |
| R2485 | T2861 | T2862 | amod | hyper-inflammatory,phenotype |
| R2486 | T2862 | T2859 | dobj | phenotype,possess |
| R2487 | T2863 | T2859 | cc | and,possess |
| R2488 | T2864 | T2859 | conj | produce,possess |
| R2489 | T2865 | T2869 | det | an,response |
| R2490 | T2866 | T2869 | amod | exaggerated,response |
| R2491 | T2867 | T2869 | amod | pro-inflammatory,response |
| R2492 | T2868 | T2869 | compound | cytokine,response |
| R2493 | T2869 | T2864 | dobj | response,produce |
| R2494 | T2870 | T2872 | nmod | [,] |
| R2495 | T2871 | T2872 | nummod | 4,] |
| R2496 | T2872 | T2869 | appos | ],response |
| R2497 | T2873 | T2872 | punct | ",",] |
| R2498 | T2874 | T2876 | nmod | [,] |
| R2499 | T2875 | T2876 | nummod | 5,] |
| R2500 | T2876 | T2872 | appos | ],] |
| R2501 | T2877 | T2857 | punct | .,shown |
| R2502 | T2878 | T2879 | aux | To,determine |
| R2503 | T2879 | T2903 | advcl | determine,stimulated |
| R2504 | T2880 | T2884 | mark | if,contribute |
| R2505 | T2881 | T2883 | amod | airway,cells |
| R2506 | T2882 | T2883 | amod | epithelial,cells |
| R2507 | T2883 | T2884 | nsubj | cells,contribute |
| R2508 | T2884 | T2903 | advcl | contribute,stimulated |
| R2509 | T2885 | T2884 | prep | to,contribute |
| R2510 | T2886 | T2889 | det | the,production |
| R2511 | T2887 | T2889 | amod | increased,production |
| R2512 | T2888 | T2889 | compound | IL-1β,production |
| R2513 | T2889 | T2885 | pobj | production,to |
| R2514 | T2890 | T2889 | prep | in,production |
| R2515 | T2891 | T2890 | pobj | patients,in |
| R2516 | T2892 | T2891 | prep | with,patients |
| R2517 | T2893 | T2892 | pobj | CF,with |
| R2518 | T2894 | T2893 | punct | ",",CF |
| R2519 | T2895 | T2893 | conj | CF,CF |
| R2520 | T2896 | T2895 | cc | and,CF |
| R2521 | T2897 | T2884 | conj | control,contribute |
| R2522 | T2898 | T2901 | amod | bronchial,lines |
| R2523 | T2899 | T2901 | amod | epithelial,lines |
| R2524 | T2900 | T2901 | compound | cell,lines |
| R2525 | T2901 | T2903 | nsubjpass | lines,stimulated |
| R2526 | T2902 | T2903 | auxpass | were,stimulated |
| R2527 | T2903 | T2903 | ROOT | stimulated,stimulated |
| R2528 | T2904 | T2903 | prep | with,stimulated |
| R2529 | T2905 | T2910 | det | the,strain |
| R2530 | T2906 | T2910 | amod | inflammasome,strain |
| R2531 | T2907 | T2910 | nmod | inducers,strain |
| R2532 | T2908 | T2910 | nsubj | P.,strain |
| R2533 | T2909 | T2910 | compound | aeruginosa,strain |
| R2534 | T2910 | T2904 | pobj | strain,with |
| R2535 | T2911 | T2917 | nsubj | PAO1,followed |
| R2536 | T2912 | T2913 | punct | (,PAO1 |
| R2537 | T2913 | T2911 | appos | PAO1,PAO1 |
| R2538 | T2914 | T2913 | punct | ),PAO1 |
| R2539 | T2915 | T2911 | cc | and,PAO1 |
| R2540 | T2916 | T2911 | conj | LPS,PAO1 |
| R2541 | T2917 | T2910 | relcl | followed,strain |
| R2542 | T2918 | T2917 | prep | by,followed |
| R2543 | T2919 | T2918 | pobj | ATP,by |
| R2544 | T2920 | T2903 | punct | .,stimulated |
| R2545 | T2921 | T2922 | amod | IL-1β,levels |
| R2546 | T2922 | T2927 | nsubj | levels,were |
| R2547 | T2923 | T2922 | prep | in,levels |
| R2548 | T2924 | T2925 | compound | cell,culture |
| R2549 | T2925 | T2926 | compound | culture,supernatants |
| R2550 | T2926 | T2923 | pobj | supernatants,in |
| R2551 | T2927 | T2930 | auxpass | were,increased |
| R2552 | T2928 | T2930 | neg | not,increased |
| R2553 | T2929 | T2930 | advmod | greatly,increased |
| R2554 | T2930 | T2930 | ROOT | increased,increased |
| R2555 | T2931 | T2930 | prep | in,increased |
| R2556 | T2932 | T2934 | det | either,CF |
| R2557 | T2933 | T2934 | det | the,CF |
| R2558 | T2934 | T2931 | pobj | CF,in |
| R2559 | T2935 | T2934 | cc | or,CF |
| R2560 | T2936 | T2930 | xcomp | control,increased |
| R2561 | T2937 | T2938 | compound | cell,lines |
| R2562 | T2938 | T2936 | dobj | lines,control |
| R2563 | T2939 | T2938 | punct | (,lines |
| R2564 | T2940 | T2941 | compound | Fig.,2a |
| R2565 | T2941 | T2938 | appos | 2a,lines |
| R2566 | T2942 | T2938 | appos | d,lines |
| R2567 | T2943 | T2938 | punct | ),lines |
| R2568 | T2944 | T2936 | punct | ",",control |
| R2569 | T2945 | T2953 | mark | although,detected |
| R2570 | T2946 | T2948 | det | a,increase |
| R2571 | T2947 | T2948 | amod | small,increase |
| R2572 | T2948 | T2953 | nsubjpass | increase,detected |
| R2573 | T2949 | T2948 | prep | in,increase |
| R2574 | T2950 | T2951 | amod | IL-1β,production |
| R2575 | T2951 | T2949 | pobj | production,in |
| R2576 | T2952 | T2953 | auxpass | was,detected |
| R2577 | T2953 | T2936 | advcl | detected,control |
| R2578 | T2954 | T2953 | prep | in,detected |
| R2579 | T2955 | T2954 | pobj | NuLi-1,in |
| R2580 | T2956 | T2955 | cc | and,NuLi-1 |
| R2581 | T2957 | T2958 | compound | CuFi-1,cells |
| R2582 | T2958 | T2955 | conj | cells,NuLi-1 |
| R2583 | T2959 | T2936 | punct | ",",control |
| R2584 | T2960 | T2936 | cc | but,control |
| R2585 | T2961 | T2962 | neg | not,in |
| R2586 | T2962 | T2936 | conj | in,control |
| R2587 | T2963 | T2966 | nummod | S9,cells |
| R2588 | T2964 | T2963 | cc | and,S9 |
| R2589 | T2965 | T2963 | conj | IB3-1,S9 |
| R2590 | T2966 | T2962 | pobj | cells,in |
| R2591 | T2967 | T2962 | punct | ",",in |
| R2592 | T2968 | T2962 | conj | by,in |
| R2593 | T2969 | T2970 | nummod | 24,hours |
| R2594 | T2970 | T2968 | pobj | hours,by |
| R2595 | T2971 | T2930 | punct | .,increased |
| R2596 | T2972 | T2978 | prep | In,were |
| R2597 | T2973 | T2972 | pobj | contrast,In |
| R2598 | T2974 | T2978 | punct | ",",were |
| R2599 | T2975 | T2977 | det | these,cells |
| R2600 | T2976 | T2977 | compound | airway,cells |
| R2601 | T2977 | T2978 | nsubj | cells,were |
| R2602 | T2978 | T2978 | ROOT | were,were |
| R2603 | T2979 | T2980 | advmod | highly,responsive |
| R2604 | T2980 | T2978 | acomp | responsive,were |
| R2605 | T2981 | T2980 | prep | to,responsive |
| R2606 | T2982 | T2984 | amod | other,stimuli |
| R2607 | T2983 | T2984 | amod | inflammatory,stimuli |
| R2608 | T2984 | T2981 | pobj | stimuli,to |
| R2609 | T2985 | T2984 | punct | ",",stimuli |
| R2610 | T2986 | T2987 | amod | such,as |
| R2611 | T2987 | T2984 | prep | as,stimuli |
| R2612 | T2988 | T2989 | compound | recombinant,IL-1β |
| R2613 | T2989 | T2987 | pobj | IL-1β,as |
| R2614 | T2990 | T2978 | punct | ",",were |
| R2615 | T2991 | T2978 | advcl | producing,were |
| R2616 | T2992 | T2993 | amod | large,quantities |
| R2617 | T2993 | T2991 | dobj | quantities,producing |
| R2618 | T2994 | T2993 | prep | of,quantities |
| R2619 | T2995 | T2994 | pobj | IL-8,of |
| R2620 | T2996 | T2993 | punct | (,quantities |
| R2621 | T2997 | T2998 | compound | Fig.,2a |
| R2622 | T2998 | T2993 | appos | 2a,quantities |
| R2623 | T2999 | T3000 | nummod | d,inserts |
| R2624 | T3000 | T2993 | appos | inserts,quantities |
| R2625 | T3001 | T2993 | punct | ),quantities |
| R2626 | T3002 | T2978 | punct | .,were |
| R11292 | T12728 | T12729 | compound | Cell,stimulation |
| R11293 | T12729 | T12729 | ROOT | stimulation,stimulation |
| R11294 | T12730 | T12729 | cc | and,stimulation |
| R11295 | T12731 | T12732 | compound | inhibitor,schedule |
| R11296 | T12732 | T12729 | conj | schedule,stimulation |
| R11297 | T12733 | T12729 | punct | .,stimulation |
| R11298 | T12734 | T12735 | nsubj | Schedule,outlines |
| R11299 | T12735 | T12735 | ROOT | outlines,outlines |
| R11300 | T12736 | T12737 | det | the,timing |
| R11301 | T12737 | T12735 | dobj | timing,outlines |
| R11302 | T12738 | T12737 | prep | of,timing |
| R11303 | T12739 | T12740 | compound | inhibitor,addition |
| R11304 | T12740 | T12738 | pobj | addition,of |
| R11305 | T12741 | T12740 | cc | and,addition |
| R11306 | T12742 | T12738 | pcomp | priming,of |
| R11307 | T12743 | T12742 | prep | in,priming |
| R11308 | T12744 | T12743 | pobj | relation,in |
| R11309 | T12745 | T12744 | prep | to,relation |
| R11310 | T12746 | T12747 | amod | inflammasome,stimulation |
| R11311 | T12747 | T12745 | pobj | stimulation,to |
| R11312 | T12748 | T12747 | punct | (,stimulation |
| R11313 | T12749 | T12747 | appos | t,stimulation |
| R11314 | T12750 | T12751 | punct | =,0 |
| R11315 | T12751 | T12749 | prep | 0,t |
| R11316 | T12752 | T12747 | punct | ),stimulation |
| R11317 | T12753 | T12735 | prep | for,outlines |
| R11318 | T12754 | T12755 | nummod | THP-1,reporter |
| R11319 | T12755 | T12753 | pobj | reporter,for |
| R11320 | T12756 | T12755 | cc | and,reporter |
| R11321 | T12757 | T12758 | compound | PBMC,cytokine |
| R11322 | T12758 | T12760 | compound | cytokine,experiments |
| R11323 | T12759 | T12760 | compound | quantification,experiments |
| R11324 | T12760 | T12755 | conj | experiments,reporter |
| R11325 | T12761 | T12735 | punct | .,outlines |
| R11326 | T12762 | T12763 | compound | Inhibitor,treatments |
| R11327 | T12763 | T12767 | nsubjpass | treatments,carried |
| R11328 | T12764 | T12763 | cc | and,treatments |
| R11329 | T12765 | T12763 | conj | stimulations,treatments |
| R11330 | T12766 | T12767 | auxpass | were,carried |
| R11331 | T12767 | T12767 | ROOT | carried,carried |
| R11332 | T12768 | T12767 | prt | out,carried |
| R11333 | T12769 | T12770 | mark | as,described |
| R11334 | T12770 | T12767 | advcl | described,carried |
| R11335 | T12771 | T12770 | prep | in,described |
| R11336 | T12772 | T12773 | det | the,Materials |
| R11337 | T12773 | T12771 | pobj | Materials,in |
| R11338 | T12774 | T12773 | cc | and,Materials |
| R11339 | T12775 | T12773 | conj | Methods,Materials |
| R11340 | T12776 | T12771 | pobj | section,in |
| R11341 | T12777 | T12767 | punct | .,carried |
| R11475 | T12939 | T12941 | nmod | Airway,cells |
| R11476 | T12940 | T12941 | amod | epithelial,cells |
| R11477 | T12941 | T12945 | nsubj | cells,contribute |
| R11478 | T12942 | T12945 | aux | do,contribute |
| R11479 | T12943 | T12945 | neg | not,contribute |
| R11480 | T12944 | T12945 | advmod | significantly,contribute |
| R11481 | T12945 | T12945 | ROOT | contribute,contribute |
| R11482 | T12946 | T12945 | prep | to,contribute |
| R11483 | T12947 | T12948 | amod | IL-1β,production |
| R11484 | T12948 | T12946 | pobj | production,to |
| R11485 | T12949 | T12945 | prep | in,contribute |
| R11486 | T12950 | T12949 | pobj | response,in |
| R11487 | T12951 | T12950 | prep | to,response |
| R11488 | T12952 | T12953 | amod | inflammasome,stimuli |
| R11489 | T12953 | T12951 | pobj | stimuli,to |
| R11490 | T12954 | T12945 | punct | .,contribute |
| R11491 | T12955 | T12957 | compound | Control,lines |
| R11492 | T12956 | T12957 | compound | cell,lines |
| R11493 | T12957 | T12989 | nsubjpass | lines,stimulated |
| R11494 | T12958 | T12957 | punct | (,lines |
| R11495 | T12959 | T12960 | punct | (,A |
| R11496 | T12960 | T12957 | appos | A,lines |
| R11497 | T12961 | T12960 | punct | ),A |
| R11498 | T12962 | T12960 | appos | S9,A |
| R11499 | T12963 | T12960 | punct | ",",A |
| R11500 | T12964 | T12965 | punct | (,C |
| R11501 | T12965 | T12960 | appos | C,A |
| R11502 | T12966 | T12965 | punct | ),C |
| R11503 | T12967 | T12960 | conj | NuLi-1,A |
| R11504 | T12968 | T12967 | punct | ),NuLi-1 |
| R11505 | T12969 | T12957 | cc | and,lines |
| R11506 | T12970 | T12974 | poss | their,lines |
| R11507 | T12971 | T12974 | amod | corresponding,lines |
| R11508 | T12972 | T12973 | compound | CF,cell |
| R11509 | T12973 | T12974 | compound | cell,lines |
| R11510 | T12974 | T12957 | conj | lines,lines |
| R11511 | T12975 | T12974 | punct | (,lines |
| R11512 | T12976 | T12979 | punct | (,IB3-1 |
| R11513 | T12977 | T12979 | nmod | B,IB3-1 |
| R11514 | T12978 | T12979 | punct | ),IB3-1 |
| R11515 | T12979 | T12985 | meta | IB3-1,CuFi-1 |
| R11516 | T12980 | T12979 | punct | ",",IB3-1 |
| R11517 | T12981 | T12979 | cc | and,IB3-1 |
| R11518 | T12982 | T12983 | punct | (,D |
| R11519 | T12983 | T12979 | conj | D,IB3-1 |
| R11520 | T12984 | T12979 | punct | ),IB3-1 |
| R11521 | T12985 | T12974 | appos | CuFi-1,lines |
| R11522 | T12986 | T12987 | punct | ),cells |
| R11523 | T12987 | T12989 | nsubjpass | cells,stimulated |
| R11524 | T12988 | T12989 | auxpass | were,stimulated |
| R11525 | T12989 | T12989 | ROOT | stimulated,stimulated |
| R11526 | T12990 | T12989 | prep | with,stimulated |
| R11527 | T12991 | T12992 | compound | P.,aeruginosa |
| R11528 | T12992 | T12990 | pobj | aeruginosa,with |
| R11529 | T12993 | T13002 | punct | (,mM |
| R11530 | T12994 | T13002 | nmod | MOI,mM |
| R11531 | T12995 | T12994 | punct | =,MOI |
| R11532 | T12996 | T12994 | nummod | 10,MOI |
| R11533 | T12997 | T12994 | punct | ),MOI |
| R11534 | T12998 | T12994 | punct | ",",MOI |
| R11535 | T12999 | T12994 | conj | ATP,MOI |
| R11536 | T13000 | T13001 | punct | (,5 |
| R11537 | T13001 | T13002 | nummod | 5,mM |
| R11538 | T13002 | T12992 | appos | mM,aeruginosa |
| R11539 | T13003 | T13002 | punct | ),mM |
| R11540 | T13004 | T13002 | punct | ",",mM |
| R11541 | T13005 | T12992 | cc | or,aeruginosa |
| R11542 | T13006 | T12992 | conj | IL-1β,aeruginosa |
| R11543 | T13007 | T13006 | punct | (,IL-1β |
| R11544 | T13008 | T13009 | nummod | 10,ng/ml |
| R11545 | T13009 | T13006 | appos | ng/ml,IL-1β |
| R11546 | T13010 | T13006 | punct | ),IL-1β |
| R11547 | T13011 | T12989 | punct | ",",stimulated |
| R11548 | T13012 | T12989 | prep | for,stimulated |
| R11549 | T13013 | T13015 | det | the,times |
| R11550 | T13014 | T13015 | amod | indicated,times |
| R11551 | T13015 | T13012 | pobj | times,for |
| R11552 | T13016 | T13015 | punct | (,times |
| R11553 | T13017 | T13021 | advmod | n,experiments |
| R11554 | T13018 | T13021 | punct | =,experiments |
| R11555 | T13019 | T13021 | nummod | 3,experiments |
| R11556 | T13020 | T13021 | amod | individual,experiments |
| R11557 | T13021 | T13015 | appos | experiments,times |
| R11558 | T13022 | T13015 | punct | ),times |
| R11559 | T13023 | T12989 | punct | .,stimulated |
| R11560 | T13024 | T13026 | nsubjpass | Cells,primed |
| R11561 | T13025 | T13026 | auxpass | were,primed |
| R11562 | T13026 | T13026 | ROOT | primed,primed |
| R11563 | T13027 | T13026 | prep | with,primed |
| R11564 | T13028 | T13027 | pobj | LPS,with |
| R11565 | T13029 | T13031 | punct | (,ng/ml |
| R11566 | T13030 | T13031 | nummod | 100,ng/ml |
| R11567 | T13031 | T13028 | appos | ng/ml,LPS |
| R11568 | T13032 | T13026 | punct | ),primed |
| R11569 | T13033 | T13026 | prep | for,primed |
| R11570 | T13034 | T13035 | nummod | 4,hours |
| R11571 | T13035 | T13033 | pobj | hours,for |
| R11572 | T13036 | T13037 | advmod | where,appropriate |
| R11573 | T13037 | T13035 | relcl | appropriate,hours |
| R11574 | T13038 | T13026 | punct | .,primed |
| R11575 | T13039 | T13040 | compound | Cell,culture |
| R11576 | T13040 | T13041 | compound | culture,supernatants |
| R11577 | T13041 | T13043 | nsubjpass | supernatants,assayed |
| R11578 | T13042 | T13043 | auxpass | were,assayed |
| R11579 | T13043 | T13043 | ROOT | assayed,assayed |
| R11580 | T13044 | T13043 | prep | for,assayed |
| R11581 | T13045 | T13048 | amod | IL-1β,production |
| R11582 | T13046 | T13045 | cc | and,IL-1β |
| R11583 | T13047 | T13045 | conj | IL-8,IL-1β |
| R11584 | T13048 | T13044 | pobj | production,for |
| R11585 | T13049 | T13048 | prep | by,production |
| R11586 | T13050 | T13049 | pobj | ELISA,by |
| R11587 | T13051 | T13043 | punct | .,assayed |
| R11588 | T13052 | T13052 | ROOT | Insert,Insert |
| R11589 | T13053 | T13052 | dobj | shows,Insert |
| R11590 | T13054 | T13055 | amod | IL-8,secretion |
| R11591 | T13055 | T13052 | npadvmod | secretion,Insert |
| R11592 | T13056 | T13052 | prep | in,Insert |
| R11593 | T13057 | T13056 | pobj | response,in |
| R11594 | T13058 | T13057 | prep | to,response |
| R11595 | T13059 | T13058 | pobj | stimulation,to |
| R11596 | T13060 | T13057 | prep | with,response |
| R11597 | T13061 | T13060 | pobj | IL-1β,with |
| R11598 | T13062 | T13061 | punct | (,IL-1β |
| R11599 | T13063 | T13064 | nummod | 10,ng/ml |
| R11600 | T13064 | T13061 | appos | ng/ml,IL-1β |
| R11601 | T13065 | T13061 | punct | ),IL-1β |
| R11602 | T13066 | T13052 | punct | .,Insert |
| R13338 | T15016 | T15017 | compound | Inflammasome,Activators |
| R13339 | T15017 | T15017 | ROOT | Activators,Activators |
| R13340 | T15018 | T15017 | punct | .,Activators |
pmc-enju-pas
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2611 | 0-6 | RB | denotes | Airway |
| T2612 | 7-17 | JJ | denotes | epithelial |
| T2613 | 18-23 | NN | denotes | cells |
| T2614 | 24-26 | VB | denotes | do |
| T2615 | 27-30 | RB | denotes | not |
| T2616 | 31-38 | VB | denotes | produce |
| T2617 | 39-50 | JJ | denotes | significant |
| T2618 | 51-58 | NN | denotes | amounts |
| T2619 | 59-61 | IN | denotes | of |
| T2620 | 62-67 | NN | denotes | IL-1β |
| T2621 | 68-70 | IN | denotes | in |
| T2622 | 71-79 | NN | denotes | response |
| T2623 | 80-82 | TO | denotes | to |
| T2624 | 83-95 | JJ | denotes | inflammasome |
| T2625 | 96-107 | NN | denotes | stimulation |
| T2626 | 108-111 | DT | denotes | The |
| T2627 | 112-125 | NN | denotes | inflammasomes |
| T2628 | 126-129 | CC | denotes | and |
| T2629 | 130-135 | PRP-DOLLAR- | denotes | their |
| T2630 | 136-146 | JJ | denotes | respective |
| T2631 | 147-157 | NN | denotes | activators |
| T2632 | 158-166 | VB | denotes | examined |
| T2633 | 167-169 | IN | denotes | in |
| T2634 | 170-174 | DT | denotes | this |
| T2635 | 175-180 | NN | denotes | study |
| T2636 | 181-184 | VB | denotes | are |
| T2637 | 185-191 | VB | denotes | listed |
| T2638 | 192-194 | IN | denotes | in |
| T2639 | 195-200 | JJ | denotes | Table |
| T2640 | 201-202 | CD | denotes | 1 |
| T2641 | 204-209 | NN | denotes | Cells |
| T2642 | 210-214 | VB | denotes | were |
| T2643 | 215-225 | VB | denotes | stimulated |
| T2644 | 226-228 | IN | denotes | in |
| T2645 | 229-239 | NN | denotes | accordance |
| T2646 | 240-244 | IN | denotes | with |
| T2647 | 245-248 | DT | denotes | the |
| T2648 | 249-257 | NN | denotes | schedule |
| T2649 | 258-260 | IN | denotes | in |
| T2650 | 261-267 | NN | denotes | Figure |
| T2651 | 268-269 | CD | denotes | 1 |
| T2652 | 271-273 | IN | denotes | In |
| T2653 | 274-276 | NN | denotes | CF |
| T2654 | 276-277 | -COMMA- | denotes | , |
| T2655 | 278-284 | NN | denotes | airway |
| T2656 | 285-295 | JJ | denotes | epithelial |
| T2657 | 296-301 | NN | denotes | cells |
| T2658 | 302-306 | VB | denotes | have |
| T2659 | 307-311 | VB | denotes | been |
| T2660 | 312-317 | VB | denotes | shown |
| T2661 | 318-320 | TO | denotes | to |
| T2662 | 321-328 | VB | denotes | possess |
| T2663 | 329-330 | DT | denotes | a |
| T2664 | 331-349 | JJ | denotes | hyper-inflammatory |
| T2665 | 350-359 | NN | denotes | phenotype |
| T2666 | 360-363 | CC | denotes | and |
| T2667 | 364-371 | VB | denotes | produce |
| T2668 | 372-374 | DT | denotes | an |
| T2669 | 375-386 | JJ | denotes | exaggerated |
| T2670 | 387-403 | JJ | denotes | pro-inflammatory |
| T2671 | 404-412 | NN | denotes | cytokine |
| T2672 | 413-421 | NN | denotes | response |
| T2673 | 422-423 | -LRB- | denotes | [ |
| T2674 | 423-424 | CD | denotes | 4 |
| T2675 | 424-425 | -RRB- | denotes | ] |
| T2676 | 425-426 | -COMMA- | denotes | , |
| T2677 | 427-428 | -LRB- | denotes | [ |
| T2678 | 428-429 | CD | denotes | 5 |
| T2679 | 429-430 | -RRB- | denotes | ] |
| T2680 | 432-434 | TO | denotes | To |
| T2681 | 435-444 | VB | denotes | determine |
| T2682 | 445-447 | IN | denotes | if |
| T2683 | 448-454 | NN | denotes | airway |
| T2684 | 455-465 | JJ | denotes | epithelial |
| T2685 | 466-471 | NN | denotes | cells |
| T2686 | 472-482 | VB | denotes | contribute |
| T2687 | 483-485 | TO | denotes | to |
| T2688 | 486-489 | DT | denotes | the |
| T2689 | 490-499 | VB | denotes | increased |
| T2690 | 500-505 | NN | denotes | IL-1β |
| T2691 | 506-516 | NN | denotes | production |
| T2692 | 517-519 | IN | denotes | in |
| T2693 | 520-528 | NN | denotes | patients |
| T2694 | 529-533 | IN | denotes | with |
| T2695 | 534-536 | NN | denotes | CF |
| T2696 | 536-537 | -COMMA- | denotes | , |
| T2697 | 538-540 | NN | denotes | CF |
| T2698 | 541-544 | CC | denotes | and |
| T2699 | 545-552 | NN | denotes | control |
| T2700 | 553-562 | JJ | denotes | bronchial |
| T2701 | 563-573 | JJ | denotes | epithelial |
| T2702 | 574-578 | NN | denotes | cell |
| T2703 | 579-584 | NN | denotes | lines |
| T2704 | 585-589 | VB | denotes | were |
| T2705 | 590-600 | VB | denotes | stimulated |
| T2706 | 601-605 | IN | denotes | with |
| T2707 | 606-609 | DT | denotes | the |
| T2708 | 610-622 | JJ | denotes | inflammasome |
| T2709 | 623-631 | NN | denotes | inducers |
| T2710 | 632-634 | NNP | denotes | P. |
| T2711 | 635-645 | NN | denotes | aeruginosa |
| T2712 | 646-652 | NN | denotes | strain |
| T2713 | 653-657 | NN | denotes | PAO1 |
| T2714 | 658-659 | -LRB- | denotes | ( |
| T2715 | 659-663 | NN | denotes | PAO1 |
| T2716 | 663-664 | -RRB- | denotes | ) |
| T2717 | 665-668 | CC | denotes | and |
| T2718 | 669-672 | NN | denotes | LPS |
| T2719 | 673-681 | VB | denotes | followed |
| T2720 | 682-684 | IN | denotes | by |
| T2721 | 685-688 | NN | denotes | ATP |
| T2722 | 690-695 | NN | denotes | IL-1β |
| T2723 | 696-702 | NN | denotes | levels |
| T2724 | 703-705 | IN | denotes | in |
| T2725 | 706-710 | NN | denotes | cell |
| T2726 | 711-718 | NN | denotes | culture |
| T2727 | 719-731 | NN | denotes | supernatants |
| T2728 | 732-736 | VB | denotes | were |
| T2729 | 737-740 | RB | denotes | not |
| T2730 | 741-748 | RB | denotes | greatly |
| T2731 | 749-758 | VB | denotes | increased |
| T2732 | 759-761 | IN | denotes | in |
| T2733 | 762-768 | CC | denotes | either |
| T2734 | 769-772 | DT | denotes | the |
| T2735 | 773-775 | NN | denotes | CF |
| T2736 | 776-778 | CC | denotes | or |
| T2737 | 779-786 | NN | denotes | control |
| T2738 | 787-791 | NN | denotes | cell |
| T2739 | 792-797 | NN | denotes | lines |
| T2740 | 798-799 | -LRB- | denotes | ( |
| T2741 | 799-803 | NNP | denotes | Fig. |
| T2742 | 804-808 | NN | denotes | 2a–d |
| T2743 | 808-809 | -RRB- | denotes | ) |
| T2744 | 809-810 | -COMMA- | denotes | , |
| T2745 | 811-819 | IN | denotes | although |
| T2746 | 820-821 | DT | denotes | a |
| T2747 | 822-827 | JJ | denotes | small |
| T2748 | 828-836 | NN | denotes | increase |
| T2749 | 837-839 | IN | denotes | in |
| T2750 | 840-845 | NN | denotes | IL-1β |
| T2751 | 846-856 | NN | denotes | production |
| T2752 | 857-860 | VB | denotes | was |
| T2753 | 861-869 | VB | denotes | detected |
| T2754 | 870-872 | IN | denotes | in |
| T2755 | 873-879 | NN | denotes | NuLi-1 |
| T2756 | 880-883 | CC | denotes | and |
| T2757 | 884-890 | NN | denotes | CuFi-1 |
| T2758 | 891-896 | NN | denotes | cells |
| T2759 | 896-897 | -COMMA- | denotes | , |
| T2760 | 898-901 | CC | denotes | but |
| T2761 | 902-905 | RB | denotes | not |
| T2762 | 906-908 | IN | denotes | in |
| T2763 | 909-911 | NN | denotes | S9 |
| T2764 | 912-915 | CC | denotes | and |
| T2765 | 916-921 | NN | denotes | IB3-1 |
| T2766 | 922-927 | NN | denotes | cells |
| T2767 | 927-928 | -COMMA- | denotes | , |
| T2768 | 929-931 | IN | denotes | by |
| T2769 | 932-934 | CD | denotes | 24 |
| T2770 | 935-940 | NN | denotes | hours |
| T2771 | 942-944 | IN | denotes | In |
| T2772 | 945-953 | NN | denotes | contrast |
| T2773 | 953-954 | -COMMA- | denotes | , |
| T2774 | 955-960 | DT | denotes | these |
| T2775 | 961-967 | NN | denotes | airway |
| T2776 | 968-973 | NN | denotes | cells |
| T2777 | 974-978 | VB | denotes | were |
| T2778 | 979-985 | RB | denotes | highly |
| T2779 | 986-996 | JJ | denotes | responsive |
| T2780 | 997-999 | TO | denotes | to |
| T2781 | 1000-1005 | JJ | denotes | other |
| T2782 | 1006-1018 | JJ | denotes | inflammatory |
| T2783 | 1019-1026 | NN | denotes | stimuli |
| T2784 | 1026-1027 | -COMMA- | denotes | , |
| T2785 | 1028-1032 | JJ | denotes | such |
| T2786 | 1033-1035 | IN | denotes | as |
| T2787 | 1036-1047 | JJ | denotes | recombinant |
| T2788 | 1048-1053 | NN | denotes | IL-1β |
| T2789 | 1053-1054 | -COMMA- | denotes | , |
| T2790 | 1055-1064 | VB | denotes | producing |
| T2791 | 1065-1070 | JJ | denotes | large |
| T2792 | 1071-1081 | NN | denotes | quantities |
| T2793 | 1082-1084 | IN | denotes | of |
| T2794 | 1085-1089 | NN | denotes | IL-8 |
| T2795 | 1090-1091 | -LRB- | denotes | ( |
| T2796 | 1091-1095 | NNP | denotes | Fig. |
| T2797 | 1096-1100 | CD | denotes | 2a–d |
| T2798 | 1101-1108 | NN | denotes | inserts |
| T2799 | 1108-1109 | -RRB- | denotes | ) |
| T12683 | 1155-1159 | NN | denotes | Cell |
| T12684 | 1160-1171 | NN | denotes | stimulation |
| T12685 | 1172-1175 | CC | denotes | and |
| T12686 | 1176-1185 | NN | denotes | inhibitor |
| T12687 | 1186-1194 | NN | denotes | schedule |
| T12688 | 1196-1204 | NNP | denotes | Schedule |
| T12689 | 1205-1213 | VB | denotes | outlines |
| T12690 | 1214-1217 | DT | denotes | the |
| T12691 | 1218-1224 | NN | denotes | timing |
| T12692 | 1225-1227 | IN | denotes | of |
| T12693 | 1228-1237 | NN | denotes | inhibitor |
| T12694 | 1238-1246 | NN | denotes | addition |
| T12695 | 1247-1250 | CC | denotes | and |
| T12696 | 1251-1258 | NN | denotes | priming |
| T12697 | 1259-1261 | IN | denotes | in |
| T12698 | 1262-1270 | NN | denotes | relation |
| T12699 | 1271-1273 | TO | denotes | to |
| T12700 | 1274-1286 | JJ | denotes | inflammasome |
| T12701 | 1287-1298 | NN | denotes | stimulation |
| T12702 | 1299-1300 | -LRB- | denotes | ( |
| T12703 | 1300-1305 | NN | denotes | t = 0 |
| T12704 | 1305-1306 | -RRB- | denotes | ) |
| T12705 | 1307-1310 | IN | denotes | for |
| T12706 | 1311-1316 | NN | denotes | THP-1 |
| T12707 | 1317-1325 | NN | denotes | reporter |
| T12708 | 1326-1329 | CC | denotes | and |
| T12709 | 1330-1334 | NN | denotes | PBMC |
| T12710 | 1335-1343 | NN | denotes | cytokine |
| T12711 | 1344-1358 | NN | denotes | quantification |
| T12712 | 1359-1370 | NN | denotes | experiments |
| T12713 | 1372-1381 | NN | denotes | Inhibitor |
| T12714 | 1382-1392 | NN | denotes | treatments |
| T12715 | 1393-1396 | CC | denotes | and |
| T12716 | 1397-1409 | NN | denotes | stimulations |
| T12717 | 1410-1414 | VB | denotes | were |
| T12718 | 1415-1422 | VB | denotes | carried |
| T12719 | 1423-1426 | RP | denotes | out |
| T12720 | 1427-1429 | RB | denotes | as |
| T12721 | 1430-1439 | VB | denotes | described |
| T12722 | 1440-1442 | IN | denotes | in |
| T12723 | 1443-1446 | DT | denotes | the |
| T12724 | 1447-1456 | NNP | denotes | Materials |
| T12725 | 1457-1460 | CC | denotes | and |
| T12726 | 1461-1468 | NNP | denotes | Methods |
| T12727 | 1469-1476 | NN | denotes | section |
| T12814 | 1522-1528 | RB | denotes | Airway |
| T12815 | 1529-1539 | JJ | denotes | epithelial |
| T12816 | 1540-1545 | NN | denotes | cells |
| T12817 | 1546-1548 | VB | denotes | do |
| T12818 | 1549-1552 | RB | denotes | not |
| T12819 | 1553-1566 | RB | denotes | significantly |
| T12820 | 1567-1577 | VB | denotes | contribute |
| T12821 | 1578-1580 | TO | denotes | to |
| T12822 | 1581-1586 | NN | denotes | IL-1β |
| T12823 | 1587-1597 | NN | denotes | production |
| T12824 | 1598-1600 | IN | denotes | in |
| T12825 | 1601-1609 | NN | denotes | response |
| T12826 | 1610-1612 | TO | denotes | to |
| T12827 | 1613-1625 | JJ | denotes | inflammasome |
| T12828 | 1626-1633 | NN | denotes | stimuli |
| T12829 | 1635-1642 | NN | denotes | Control |
| T12830 | 1643-1647 | NN | denotes | cell |
| T12831 | 1648-1653 | NN | denotes | lines |
| T12832 | 1654-1655 | -LRB- | denotes | ( |
| T12833 | 1655-1656 | -LRB- | denotes | ( |
| T12834 | 1656-1657 | NN | denotes | A |
| T12835 | 1657-1658 | -RRB- | denotes | ) |
| T12836 | 1659-1661 | NN | denotes | S9 |
| T12837 | 1661-1662 | -COMMA- | denotes | , |
| T12838 | 1663-1664 | -LRB- | denotes | ( |
| T12839 | 1664-1665 | NN | denotes | C |
| T12840 | 1665-1666 | -RRB- | denotes | ) |
| T12841 | 1667-1673 | NN | denotes | NuLi-1 |
| T12842 | 1673-1674 | -RRB- | denotes | ) |
| T12843 | 1675-1678 | CC | denotes | and |
| T12844 | 1679-1684 | PRP-DOLLAR- | denotes | their |
| T12845 | 1685-1698 | VB | denotes | corresponding |
| T12846 | 1699-1701 | NN | denotes | CF |
| T12847 | 1702-1706 | NN | denotes | cell |
| T12848 | 1707-1712 | NN | denotes | lines |
| T12849 | 1713-1714 | -LRB- | denotes | ( |
| T12850 | 1714-1715 | -LRB- | denotes | ( |
| T12851 | 1715-1716 | NN | denotes | B |
| T12852 | 1716-1717 | -RRB- | denotes | ) |
| T12853 | 1718-1723 | NN | denotes | IB3-1 |
| T12854 | 1723-1724 | -COMMA- | denotes | , |
| T12855 | 1725-1728 | CC | denotes | and |
| T12856 | 1729-1730 | -LRB- | denotes | ( |
| T12857 | 1730-1731 | NN | denotes | D |
| T12858 | 1731-1732 | -RRB- | denotes | ) |
| T12859 | 1733-1739 | NN | denotes | CuFi-1 |
| T12860 | 1739-1740 | -RRB- | denotes | ) |
| T12861 | 1741-1746 | NN | denotes | cells |
| T12862 | 1747-1751 | VB | denotes | were |
| T12863 | 1752-1762 | VB | denotes | stimulated |
| T12864 | 1763-1767 | IN | denotes | with |
| T12865 | 1768-1770 | NNP | denotes | P. |
| T12866 | 1771-1781 | NN | denotes | aeruginosa |
| T12867 | 1782-1783 | -LRB- | denotes | ( |
| T12868 | 1783-1791 | NN | denotes | MOI = 10 |
| T12869 | 1791-1792 | -RRB- | denotes | ) |
| T12870 | 1792-1793 | -COMMA- | denotes | , |
| T12871 | 1794-1797 | NN | denotes | ATP |
| T12872 | 1798-1799 | -LRB- | denotes | ( |
| T12873 | 1799-1800 | CD | denotes | 5 |
| T12874 | 1801-1803 | NN | denotes | mM |
| T12875 | 1803-1804 | -RRB- | denotes | ) |
| T12876 | 1804-1805 | -COMMA- | denotes | , |
| T12877 | 1806-1808 | CC | denotes | or |
| T12878 | 1809-1814 | NN | denotes | IL-1β |
| T12879 | 1815-1816 | -LRB- | denotes | ( |
| T12880 | 1816-1818 | CD | denotes | 10 |
| T12881 | 1819-1824 | NN | denotes | ng/ml |
| T12882 | 1824-1825 | -RRB- | denotes | ) |
| T12883 | 1825-1826 | -COMMA- | denotes | , |
| T12884 | 1827-1830 | IN | denotes | for |
| T12885 | 1831-1834 | DT | denotes | the |
| T12886 | 1835-1844 | VB | denotes | indicated |
| T12887 | 1845-1850 | NN | denotes | times |
| T12888 | 1851-1852 | -LRB- | denotes | ( |
| T12889 | 1852-1857 | NN | denotes | n = 3 |
| T12890 | 1858-1868 | JJ | denotes | individual |
| T12891 | 1869-1880 | NN | denotes | experiments |
| T12892 | 1880-1881 | -RRB- | denotes | ) |
| T12893 | 1883-1888 | NN | denotes | Cells |
| T12894 | 1889-1893 | VB | denotes | were |
| T12895 | 1894-1900 | VB | denotes | primed |
| T12896 | 1901-1905 | IN | denotes | with |
| T12897 | 1906-1909 | NN | denotes | LPS |
| T12898 | 1910-1911 | -LRB- | denotes | ( |
| T12899 | 1911-1914 | CD | denotes | 100 |
| T12900 | 1915-1920 | NN | denotes | ng/ml |
| T12901 | 1920-1921 | -RRB- | denotes | ) |
| T12902 | 1922-1925 | IN | denotes | for |
| T12903 | 1926-1927 | CD | denotes | 4 |
| T12904 | 1928-1933 | NN | denotes | hours |
| T12905 | 1934-1939 | WRB | denotes | where |
| T12906 | 1940-1951 | JJ | denotes | appropriate |
| T12907 | 1953-1957 | NN | denotes | Cell |
| T12908 | 1958-1965 | NN | denotes | culture |
| T12909 | 1966-1978 | NN | denotes | supernatants |
| T12910 | 1979-1983 | VB | denotes | were |
| T12911 | 1984-1991 | VB | denotes | assayed |
| T12912 | 1992-1995 | IN | denotes | for |
| T12913 | 1996-2001 | NN | denotes | IL-1β |
| T12914 | 2002-2005 | CC | denotes | and |
| T12915 | 2006-2010 | NN | denotes | IL-8 |
| T12916 | 2011-2021 | NN | denotes | production |
| T12917 | 2022-2024 | IN | denotes | by |
| T12918 | 2025-2030 | NN | denotes | ELISA |
| T12919 | 2032-2038 | NN | denotes | Insert |
| T12920 | 2039-2044 | VB | denotes | shows |
| T12921 | 2045-2049 | NN | denotes | IL-8 |
| T12922 | 2050-2059 | NN | denotes | secretion |
| T12923 | 2060-2062 | IN | denotes | in |
| T12924 | 2063-2071 | NN | denotes | response |
| T12925 | 2072-2074 | TO | denotes | to |
| T12926 | 2075-2086 | NN | denotes | stimulation |
| T12927 | 2087-2091 | IN | denotes | with |
| T12928 | 2092-2097 | NN | denotes | IL-1β |
| T12929 | 2098-2099 | -LRB- | denotes | ( |
| T12930 | 2099-2101 | CD | denotes | 10 |
| T12931 | 2102-2107 | NN | denotes | ng/ml |
| T12932 | 2107-2108 | -RRB- | denotes | ) |
| T15014 | 2153-2165 | JJ | denotes | Inflammasome |
| T15015 | 2166-2176 | NN | denotes | Activators |
| R2233 | T2612 | T2611 | arg1Of | epithelial,Airway |
| R2234 | T2613 | T2612 | arg1Of | cells,epithelial |
| R2235 | T2613 | T2614 | arg1Of | cells,do |
| R2236 | T2613 | T2616 | arg1Of | cells,produce |
| R2237 | T2616 | T2614 | arg2Of | produce,do |
| R2238 | T2616 | T2615 | arg1Of | produce,not |
| R2239 | T2616 | T2621 | arg1Of | produce,in |
| R2240 | T2618 | T2616 | arg2Of | amounts,produce |
| R2241 | T2618 | T2617 | arg1Of | amounts,significant |
| R2242 | T2618 | T2619 | arg1Of | amounts,of |
| R2243 | T2620 | T2619 | arg2Of | IL-1β,of |
| R2244 | T2621 | T2623 | arg1Of | in,to |
| R2245 | T2622 | T2621 | arg2Of | response,in |
| R2246 | T2625 | T2621 | arg3Of | stimulation,in |
| R2247 | T2625 | T2624 | arg1Of | stimulation,inflammasome |
| R2248 | T2627 | T2626 | arg1Of | inflammasomes,The |
| R2249 | T2627 | T2628 | arg1Of | inflammasomes,and |
| R2250 | T2628 | T2636 | arg1Of | and,are |
| R2251 | T2628 | T2637 | arg2Of | and,listed |
| R2252 | T2631 | T2628 | arg2Of | activators,and |
| R2253 | T2631 | T2629 | arg1Of | activators,their |
| R2254 | T2631 | T2630 | arg1Of | activators,respective |
| R2255 | T2631 | T2632 | arg2Of | activators,examined |
| R2256 | T2632 | T2633 | arg1Of | examined,in |
| R2257 | T2635 | T2633 | arg2Of | study,in |
| R2258 | T2635 | T2634 | arg1Of | study,this |
| R2259 | T2637 | T2636 | arg2Of | listed,are |
| R2260 | T2637 | T2638 | arg1Of | listed,in |
| R2261 | T2640 | T2638 | arg2Of | 1,in |
| R2262 | T2640 | T2639 | arg1Of | 1,Table |
| R2263 | T2641 | T2642 | arg1Of | Cells,were |
| R2264 | T2641 | T2643 | arg2Of | Cells,stimulated |
| R2265 | T2643 | T2642 | arg2Of | stimulated,were |
| R2266 | T2643 | T2644 | arg1Of | stimulated,in |
| R2267 | T2645 | T2644 | arg2Of | accordance,in |
| R2268 | T2645 | T2646 | arg1Of | accordance,with |
| R2269 | T2648 | T2646 | arg2Of | schedule,with |
| R2270 | T2648 | T2647 | arg1Of | schedule,the |
| R2271 | T2648 | T2649 | arg1Of | schedule,in |
| R2272 | T2650 | T2649 | arg2Of | Figure,in |
| R2273 | T2650 | T2651 | arg1Of | Figure,1 |
| R2274 | T2653 | T2652 | arg2Of | CF,In |
| R2275 | T2657 | T2655 | arg1Of | cells,airway |
| R2276 | T2657 | T2656 | arg1Of | cells,epithelial |
| R2277 | T2657 | T2658 | arg1Of | cells,have |
| R2278 | T2657 | T2659 | arg1Of | cells,been |
| R2279 | T2657 | T2660 | arg2Of | cells,shown |
| R2280 | T2657 | T2662 | arg1Of | cells,possess |
| R2281 | T2657 | T2667 | arg1Of | cells,produce |
| R2282 | T2660 | T2652 | arg1Of | shown,In |
| R2283 | T2660 | T2654 | arg1Of | shown,"," |
| R2284 | T2660 | T2658 | arg2Of | shown,have |
| R2285 | T2660 | T2659 | arg2Of | shown,been |
| R2286 | T2662 | T2666 | arg1Of | possess,and |
| R2287 | T2665 | T2662 | arg2Of | phenotype,possess |
| R2288 | T2665 | T2663 | arg1Of | phenotype,a |
| R2289 | T2665 | T2664 | arg1Of | phenotype,hyper-inflammatory |
| R2290 | T2666 | T2660 | arg3Of | and,shown |
| R2291 | T2666 | T2661 | arg1Of | and,to |
| R2292 | T2667 | T2666 | arg2Of | produce,and |
| R2293 | T2667 | T2676 | arg1Of | produce,"," |
| R2294 | T2667 | T2677 | arg1Of | produce,[ |
| R2295 | T2672 | T2667 | arg2Of | response,produce |
| R2296 | T2672 | T2668 | arg1Of | response,an |
| R2297 | T2672 | T2669 | arg1Of | response,exaggerated |
| R2298 | T2672 | T2670 | arg1Of | response,pro-inflammatory |
| R2299 | T2672 | T2671 | arg1Of | response,cytokine |
| R2300 | T2672 | T2673 | arg1Of | response,[ |
| R2301 | T2674 | T2673 | arg2Of | 4,[ |
| R2302 | T2675 | T2673 | arg3Of | ],[ |
| R2303 | T2678 | T2677 | arg2Of | 5,[ |
| R2304 | T2679 | T2677 | arg3Of | ],[ |
| R2305 | T2681 | T2680 | arg1Of | determine,To |
| R2306 | T2685 | T2683 | arg1Of | cells,airway |
| R2307 | T2685 | T2684 | arg1Of | cells,epithelial |
| R2308 | T2685 | T2686 | arg1Of | cells,contribute |
| R2309 | T2686 | T2681 | arg2Of | contribute,determine |
| R2310 | T2686 | T2682 | arg1Of | contribute,if |
| R2311 | T2686 | T2687 | arg1Of | contribute,to |
| R2312 | T2691 | T2687 | arg2Of | production,to |
| R2313 | T2691 | T2688 | arg1Of | production,the |
| R2314 | T2691 | T2689 | arg2Of | production,increased |
| R2315 | T2691 | T2690 | arg1Of | production,IL-1β |
| R2316 | T2691 | T2692 | arg1Of | production,in |
| R2317 | T2693 | T2692 | arg2Of | patients,in |
| R2318 | T2693 | T2694 | arg1Of | patients,with |
| R2319 | T2695 | T2694 | arg2Of | CF,with |
| R2320 | T2697 | T2698 | arg1Of | CF,and |
| R2321 | T2699 | T2698 | arg2Of | control,and |
| R2322 | T2703 | T2697 | arg1Of | lines,CF |
| R2323 | T2703 | T2699 | arg1Of | lines,control |
| R2324 | T2703 | T2700 | arg1Of | lines,bronchial |
| R2325 | T2703 | T2701 | arg1Of | lines,epithelial |
| R2326 | T2703 | T2702 | arg1Of | lines,cell |
| R2327 | T2703 | T2704 | arg1Of | lines,were |
| R2328 | T2703 | T2705 | arg2Of | lines,stimulated |
| R2329 | T2705 | T2680 | modOf | stimulated,To |
| R2330 | T2705 | T2696 | arg1Of | stimulated,"," |
| R2331 | T2705 | T2704 | arg2Of | stimulated,were |
| R2332 | T2705 | T2706 | arg1Of | stimulated,with |
| R2333 | T2709 | T2708 | arg1Of | inducers,inflammasome |
| R2334 | T2713 | T2710 | arg1Of | PAO1,P. |
| R2335 | T2713 | T2711 | arg1Of | PAO1,aeruginosa |
| R2336 | T2713 | T2712 | arg1Of | PAO1,strain |
| R2337 | T2713 | T2714 | arg1Of | PAO1,( |
| R2338 | T2713 | T2717 | arg1Of | PAO1,and |
| R2339 | T2715 | T2714 | arg2Of | PAO1,( |
| R2340 | T2716 | T2714 | arg3Of | ),( |
| R2341 | T2717 | T2706 | arg2Of | and,with |
| R2342 | T2717 | T2707 | arg1Of | and,the |
| R2343 | T2717 | T2709 | arg1Of | and,inducers |
| R2344 | T2718 | T2717 | arg2Of | LPS,and |
| R2345 | T2718 | T2719 | arg2Of | LPS,followed |
| R2346 | T2721 | T2719 | arg1Of | ATP,followed |
| R2347 | T2721 | T2720 | arg2Of | ATP,by |
| R2348 | T2723 | T2722 | arg1Of | levels,IL-1β |
| R2349 | T2723 | T2724 | arg1Of | levels,in |
| R2350 | T2723 | T2728 | arg1Of | levels,were |
| R2351 | T2723 | T2731 | arg2Of | levels,increased |
| R2352 | T2727 | T2724 | arg2Of | supernatants,in |
| R2353 | T2727 | T2725 | arg1Of | supernatants,cell |
| R2354 | T2727 | T2726 | arg1Of | supernatants,culture |
| R2355 | T2731 | T2728 | arg2Of | increased,were |
| R2356 | T2731 | T2729 | arg1Of | increased,not |
| R2357 | T2731 | T2730 | arg1Of | increased,greatly |
| R2358 | T2731 | T2732 | arg1Of | increased,in |
| R2359 | T2731 | T2744 | arg1Of | increased,"," |
| R2360 | T2731 | T2745 | arg1Of | increased,although |
| R2361 | T2735 | T2736 | arg1Of | CF,or |
| R2362 | T2737 | T2736 | arg2Of | control,or |
| R2363 | T2739 | T2732 | arg2Of | lines,in |
| R2364 | T2739 | T2733 | arg1Of | lines,either |
| R2365 | T2739 | T2734 | arg1Of | lines,the |
| R2366 | T2739 | T2735 | arg1Of | lines,CF |
| R2367 | T2739 | T2737 | arg1Of | lines,control |
| R2368 | T2739 | T2738 | arg1Of | lines,cell |
| R2369 | T2739 | T2740 | arg1Of | lines,( |
| R2370 | T2742 | T2740 | arg2Of | 2a–d,( |
| R2371 | T2742 | T2741 | arg1Of | 2a–d,Fig. |
| R2372 | T2743 | T2740 | arg3Of | ),( |
| R2373 | T2748 | T2746 | arg1Of | increase,a |
| R2374 | T2748 | T2747 | arg1Of | increase,small |
| R2375 | T2748 | T2749 | arg1Of | increase,in |
| R2376 | T2748 | T2752 | arg1Of | increase,was |
| R2377 | T2748 | T2753 | arg2Of | increase,detected |
| R2378 | T2751 | T2749 | arg2Of | production,in |
| R2379 | T2751 | T2750 | arg1Of | production,IL-1β |
| R2380 | T2753 | T2745 | arg2Of | detected,although |
| R2381 | T2753 | T2752 | arg2Of | detected,was |
| R2382 | T2753 | T2754 | arg1Of | detected,in |
| R2383 | T2753 | T2762 | arg1Of | detected,in |
| R2384 | T2753 | T2767 | arg1Of | detected,"," |
| R2385 | T2753 | T2768 | arg1Of | detected,by |
| R2386 | T2754 | T2760 | arg1Of | in,but |
| R2387 | T2755 | T2756 | arg1Of | NuLi-1,and |
| R2388 | T2756 | T2754 | arg2Of | and,in |
| R2389 | T2758 | T2756 | arg2Of | cells,and |
| R2390 | T2758 | T2757 | arg1Of | cells,CuFi-1 |
| R2391 | T2760 | T2759 | arg1Of | but,"," |
| R2392 | T2762 | T2760 | arg2Of | in,but |
| R2393 | T2762 | T2761 | arg1Of | in,not |
| R2394 | T2763 | T2764 | arg1Of | S9,and |
| R2395 | T2765 | T2764 | arg2Of | IB3-1,and |
| R2396 | T2766 | T2762 | arg2Of | cells,in |
| R2397 | T2766 | T2763 | arg1Of | cells,S9 |
| R2398 | T2766 | T2765 | arg1Of | cells,IB3-1 |
| R2399 | T2770 | T2768 | arg2Of | hours,by |
| R2400 | T2770 | T2769 | arg1Of | hours,24 |
| R2401 | T2772 | T2771 | arg2Of | contrast,In |
| R2402 | T2776 | T2774 | arg1Of | cells,these |
| R2403 | T2776 | T2775 | arg1Of | cells,airway |
| R2404 | T2776 | T2777 | arg1Of | cells,were |
| R2405 | T2776 | T2779 | arg1Of | cells,responsive |
| R2406 | T2777 | T2771 | arg1Of | were,In |
| R2407 | T2777 | T2773 | arg1Of | were,"," |
| R2408 | T2777 | T2789 | arg1Of | were,"," |
| R2409 | T2777 | T2790 | modOf | were,producing |
| R2410 | T2779 | T2777 | arg2Of | responsive,were |
| R2411 | T2779 | T2778 | arg1Of | responsive,highly |
| R2412 | T2779 | T2780 | arg1Of | responsive,to |
| R2413 | T2783 | T2780 | arg2Of | stimuli,to |
| R2414 | T2783 | T2781 | arg1Of | stimuli,other |
| R2415 | T2783 | T2782 | arg1Of | stimuli,inflammatory |
| R2416 | T2783 | T2784 | arg1Of | stimuli,"," |
| R2417 | T2783 | T2786 | arg1Of | stimuli,as |
| R2418 | T2786 | T2785 | arg1Of | as,such |
| R2419 | T2788 | T2786 | arg2Of | IL-1β,as |
| R2420 | T2788 | T2787 | arg1Of | IL-1β,recombinant |
| R2421 | T2790 | T2795 | arg1Of | producing,( |
| R2422 | T2792 | T2790 | arg2Of | quantities,producing |
| R2423 | T2792 | T2791 | arg1Of | quantities,large |
| R2424 | T2792 | T2793 | arg1Of | quantities,of |
| R2425 | T2794 | T2793 | arg2Of | IL-8,of |
| R2426 | T2796 | T2797 | arg1Of | Fig.,2a–d |
| R2427 | T2798 | T2795 | arg2Of | inserts,( |
| R2428 | T2798 | T2796 | arg1Of | inserts,Fig. |
| R2429 | T2799 | T2795 | arg3Of | ),( |
| R11248 | T12684 | T12683 | arg1Of | stimulation,Cell |
| R11249 | T12684 | T12685 | arg1Of | stimulation,and |
| R11250 | T12687 | T12685 | arg2Of | schedule,and |
| R11251 | T12687 | T12686 | arg1Of | schedule,inhibitor |
| R11252 | T12688 | T12689 | arg1Of | Schedule,outlines |
| R11253 | T12689 | T12697 | arg1Of | outlines,in |
| R11254 | T12691 | T12689 | arg2Of | timing,outlines |
| R11255 | T12691 | T12690 | arg1Of | timing,the |
| R11256 | T12691 | T12692 | arg1Of | timing,of |
| R11257 | T12694 | T12693 | arg1Of | addition,inhibitor |
| R11258 | T12694 | T12695 | arg1Of | addition,and |
| R11259 | T12695 | T12692 | arg2Of | and,of |
| R11260 | T12696 | T12695 | arg2Of | priming,and |
| R11261 | T12698 | T12697 | arg2Of | relation,in |
| R11262 | T12698 | T12699 | arg1Of | relation,to |
| R11263 | T12701 | T12699 | arg2Of | stimulation,to |
| R11264 | T12701 | T12700 | arg1Of | stimulation,inflammasome |
| R11265 | T12701 | T12702 | arg1Of | stimulation,( |
| R11266 | T12701 | T12705 | arg1Of | stimulation,for |
| R11267 | T12703 | T12702 | arg2Of | t = 0,( |
| R11268 | T12704 | T12702 | arg3Of | ),( |
| R11269 | T12707 | T12706 | arg1Of | reporter,THP-1 |
| R11270 | T12707 | T12708 | arg1Of | reporter,and |
| R11271 | T12708 | T12705 | arg2Of | and,for |
| R11272 | T12712 | T12708 | arg2Of | experiments,and |
| R11273 | T12712 | T12709 | arg1Of | experiments,PBMC |
| R11274 | T12712 | T12710 | arg1Of | experiments,cytokine |
| R11275 | T12712 | T12711 | arg1Of | experiments,quantification |
| R11276 | T12714 | T12713 | arg1Of | treatments,Inhibitor |
| R11277 | T12714 | T12715 | arg1Of | treatments,and |
| R11278 | T12715 | T12717 | arg1Of | and,were |
| R11279 | T12715 | T12718 | arg2Of | and,carried |
| R11280 | T12716 | T12715 | arg2Of | stimulations,and |
| R11281 | T12718 | T12717 | arg2Of | carried,were |
| R11282 | T12718 | T12719 | arg1Of | carried,out |
| R11283 | T12718 | T12720 | arg1Of | carried,as |
| R11284 | T12721 | T12720 | arg2Of | described,as |
| R11285 | T12721 | T12722 | arg1Of | described,in |
| R11286 | T12724 | T12725 | arg1Of | Materials,and |
| R11287 | T12726 | T12725 | arg2Of | Methods,and |
| R11288 | T12727 | T12722 | arg2Of | section,in |
| R11289 | T12727 | T12723 | arg1Of | section,the |
| R11290 | T12727 | T12724 | arg1Of | section,Materials |
| R11291 | T12727 | T12726 | arg1Of | section,Methods |
| R11356 | T12815 | T12814 | arg1Of | epithelial,Airway |
| R11357 | T12816 | T12815 | arg1Of | cells,epithelial |
| R11358 | T12816 | T12817 | arg1Of | cells,do |
| R11359 | T12816 | T12820 | arg1Of | cells,contribute |
| R11360 | T12820 | T12817 | arg2Of | contribute,do |
| R11361 | T12820 | T12818 | arg1Of | contribute,not |
| R11362 | T12820 | T12819 | arg1Of | contribute,significantly |
| R11363 | T12820 | T12821 | arg1Of | contribute,to |
| R11364 | T12820 | T12824 | arg1Of | contribute,in |
| R11365 | T12823 | T12821 | arg2Of | production,to |
| R11366 | T12823 | T12822 | arg1Of | production,IL-1β |
| R11367 | T12825 | T12824 | arg2Of | response,in |
| R11368 | T12825 | T12826 | arg1Of | response,to |
| R11369 | T12828 | T12826 | arg2Of | stimuli,to |
| R11370 | T12828 | T12827 | arg1Of | stimuli,inflammasome |
| R11371 | T12831 | T12829 | arg1Of | lines,Control |
| R11372 | T12831 | T12830 | arg1Of | lines,cell |
| R11373 | T12831 | T12832 | arg1Of | lines,( |
| R11374 | T12831 | T12843 | arg1Of | lines,and |
| R11375 | T12834 | T12833 | arg2Of | A,( |
| R11376 | T12835 | T12833 | arg3Of | ),( |
| R11377 | T12836 | T12832 | arg2Of | S9,( |
| R11378 | T12836 | T12833 | arg1Of | S9,( |
| R11379 | T12836 | T12837 | arg1Of | S9,"," |
| R11380 | T12839 | T12838 | arg2Of | C,( |
| R11381 | T12840 | T12838 | arg3Of | ),( |
| R11382 | T12841 | T12837 | arg2Of | NuLi-1,"," |
| R11383 | T12841 | T12838 | arg1Of | NuLi-1,( |
| R11384 | T12842 | T12832 | arg3Of | ),( |
| R11385 | T12848 | T12843 | arg2Of | lines,and |
| R11386 | T12848 | T12844 | arg1Of | lines,their |
| R11387 | T12848 | T12845 | arg1Of | lines,corresponding |
| R11388 | T12848 | T12846 | arg1Of | lines,CF |
| R11389 | T12848 | T12847 | arg1Of | lines,cell |
| R11390 | T12848 | T12849 | arg1Of | lines,( |
| R11391 | T12848 | T12862 | modOf | lines,were |
| R11392 | T12851 | T12850 | arg2Of | B,( |
| R11393 | T12852 | T12850 | arg3Of | ),( |
| R11394 | T12853 | T12855 | arg1Of | IB3-1,and |
| R11395 | T12855 | T12849 | arg2Of | and,( |
| R11396 | T12855 | T12850 | arg1Of | and,( |
| R11397 | T12855 | T12854 | arg1Of | and,"," |
| R11398 | T12857 | T12856 | arg2Of | D,( |
| R11399 | T12858 | T12856 | arg3Of | ),( |
| R11400 | T12859 | T12855 | arg2Of | CuFi-1,and |
| R11401 | T12859 | T12856 | arg1Of | CuFi-1,( |
| R11402 | T12860 | T12849 | arg3Of | ),( |
| R11403 | T12861 | T12862 | arg1Of | cells,were |
| R11404 | T12861 | T12863 | arg2Of | cells,stimulated |
| R11405 | T12863 | T12862 | arg2Of | stimulated,were |
| R11406 | T12863 | T12864 | arg1Of | stimulated,with |
| R11407 | T12866 | T12865 | arg1Of | aeruginosa,P. |
| R11408 | T12866 | T12867 | arg1Of | aeruginosa,( |
| R11409 | T12866 | T12870 | arg1Of | aeruginosa,"," |
| R11410 | T12868 | T12867 | arg2Of | MOI = 10,( |
| R11411 | T12869 | T12867 | arg3Of | ),( |
| R11412 | T12870 | T12877 | arg1Of | ",",or |
| R11413 | T12871 | T12870 | arg2Of | ATP,"," |
| R11414 | T12871 | T12872 | arg1Of | ATP,( |
| R11415 | T12874 | T12872 | arg2Of | mM,( |
| R11416 | T12874 | T12873 | arg1Of | mM,5 |
| R11417 | T12875 | T12872 | arg3Of | ),( |
| R11418 | T12877 | T12864 | arg2Of | or,with |
| R11419 | T12877 | T12876 | arg1Of | or,"," |
| R11420 | T12877 | T12883 | arg1Of | or,"," |
| R11421 | T12877 | T12884 | arg1Of | or,for |
| R11422 | T12878 | T12877 | arg2Of | IL-1β,or |
| R11423 | T12878 | T12879 | arg1Of | IL-1β,( |
| R11424 | T12881 | T12879 | arg2Of | ng/ml,( |
| R11425 | T12881 | T12880 | arg1Of | ng/ml,10 |
| R11426 | T12882 | T12879 | arg3Of | ),( |
| R11427 | T12887 | T12884 | arg2Of | times,for |
| R11428 | T12887 | T12885 | arg1Of | times,the |
| R11429 | T12887 | T12886 | arg2Of | times,indicated |
| R11430 | T12887 | T12888 | arg1Of | times,( |
| R11431 | T12891 | T12888 | arg2Of | experiments,( |
| R11432 | T12891 | T12889 | arg1Of | experiments,n = 3 |
| R11433 | T12891 | T12890 | arg1Of | experiments,individual |
| R11434 | T12892 | T12888 | arg3Of | ),( |
| R11435 | T12893 | T12894 | arg1Of | Cells,were |
| R11436 | T12893 | T12895 | arg2Of | Cells,primed |
| R11437 | T12895 | T12894 | arg2Of | primed,were |
| R11438 | T12895 | T12896 | arg1Of | primed,with |
| R11439 | T12895 | T12902 | arg1Of | primed,for |
| R11440 | T12895 | T12905 | arg1Of | primed,where |
| R11441 | T12897 | T12896 | arg2Of | LPS,with |
| R11442 | T12897 | T12898 | arg1Of | LPS,( |
| R11443 | T12900 | T12898 | arg2Of | ng/ml,( |
| R11444 | T12900 | T12899 | arg1Of | ng/ml,100 |
| R11445 | T12901 | T12898 | arg3Of | ),( |
| R11446 | T12904 | T12902 | arg2Of | hours,for |
| R11447 | T12904 | T12903 | arg1Of | hours,4 |
| R11448 | T12906 | T12905 | arg2Of | appropriate,where |
| R11449 | T12909 | T12907 | arg1Of | supernatants,Cell |
| R11450 | T12909 | T12908 | arg1Of | supernatants,culture |
| R11451 | T12909 | T12910 | arg1Of | supernatants,were |
| R11452 | T12909 | T12911 | arg2Of | supernatants,assayed |
| R11453 | T12911 | T12910 | arg2Of | assayed,were |
| R11454 | T12911 | T12912 | arg1Of | assayed,for |
| R11455 | T12913 | T12914 | arg1Of | IL-1β,and |
| R11456 | T12915 | T12914 | arg2Of | IL-8,and |
| R11457 | T12916 | T12912 | arg2Of | production,for |
| R11458 | T12916 | T12913 | arg1Of | production,IL-1β |
| R11459 | T12916 | T12915 | arg1Of | production,IL-8 |
| R11460 | T12916 | T12917 | arg1Of | production,by |
| R11461 | T12918 | T12917 | arg2Of | ELISA,by |
| R11462 | T12919 | T12920 | arg1Of | Insert,shows |
| R11463 | T12920 | T12923 | arg1Of | shows,in |
| R11464 | T12922 | T12920 | arg2Of | secretion,shows |
| R11465 | T12922 | T12921 | arg1Of | secretion,IL-8 |
| R11466 | T12924 | T12923 | arg2Of | response,in |
| R11467 | T12924 | T12925 | arg1Of | response,to |
| R11468 | T12926 | T12925 | arg2Of | stimulation,to |
| R11469 | T12926 | T12927 | arg1Of | stimulation,with |
| R11470 | T12928 | T12927 | arg2Of | IL-1β,with |
| R11471 | T12928 | T12929 | arg1Of | IL-1β,( |
| R11472 | T12931 | T12929 | arg2Of | ng/ml,( |
| R11473 | T12931 | T12930 | arg1Of | ng/ml,10 |
| R11474 | T12932 | T12929 | arg3Of | ),( |
| R13337 | T15015 | T15014 | arg1Of | Activators,Inflammasome |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2604 | 0-107 | Sentence | denotes | Airway epithelial cells do not produce significant amounts of IL-1β in response to inflammasome stimulation |
| T2605 | 108-203 | Sentence | denotes | The inflammasomes and their respective activators examined in this study are listed in Table 1. |
| T2606 | 204-270 | Sentence | denotes | Cells were stimulated in accordance with the schedule in Figure 1. |
| T2607 | 271-431 | Sentence | denotes | In CF, airway epithelial cells have been shown to possess a hyper-inflammatory phenotype and produce an exaggerated pro-inflammatory cytokine response [4], [5]. |
| T2608 | 432-689 | Sentence | denotes | To determine if airway epithelial cells contribute to the increased IL-1β production in patients with CF, CF and control bronchial epithelial cell lines were stimulated with the inflammasome inducers P. aeruginosa strain PAO1 (PAO1) and LPS followed by ATP. |
| T2609 | 690-941 | Sentence | denotes | IL-1β levels in cell culture supernatants were not greatly increased in either the CF or control cell lines (Fig. 2a–d), although a small increase in IL-1β production was detected in NuLi-1 and CuFi-1 cells, but not in S9 and IB3-1 cells, by 24 hours. |
| T2610 | 942-1110 | Sentence | denotes | In contrast, these airway cells were highly responsive to other inflammatory stimuli, such as recombinant IL-1β, producing large quantities of IL-8 (Fig. 2a–d inserts). |
| T12680 | 1155-1195 | Sentence | denotes | Cell stimulation and inhibitor schedule. |
| T12681 | 1196-1371 | Sentence | denotes | Schedule outlines the timing of inhibitor addition and priming in relation to inflammasome stimulation (t = 0) for THP-1 reporter and PBMC cytokine quantification experiments. |
| T12682 | 1372-1477 | Sentence | denotes | Inhibitor treatments and stimulations were carried out as described in the Materials and Methods section. |
| T12809 | 1522-1634 | Sentence | denotes | Airway epithelial cells do not significantly contribute to IL-1β production in response to inflammasome stimuli. |
| T12810 | 1635-1882 | Sentence | denotes | Control cell lines ((A) S9, (C) NuLi-1) and their corresponding CF cell lines ((B) IB3-1, and (D) CuFi-1) cells were stimulated with P. aeruginosa (MOI = 10), ATP (5 mM), or IL-1β (10 ng/ml), for the indicated times (n = 3 individual experiments). |
| T12811 | 1883-1952 | Sentence | denotes | Cells were primed with LPS (100 ng/ml) for 4 hours where appropriate. |
| T12812 | 1953-2031 | Sentence | denotes | Cell culture supernatants were assayed for IL-1β and IL-8 production by ELISA. |
| T12813 | 2032-2109 | Sentence | denotes | Insert shows IL-8 secretion in response to stimulation with IL-1β (10 ng/ml). |
| T15013 | 2153-2177 | Sentence | denotes | Inflammasome Activators. |
| T43 | 0-107 | Sentence | denotes | Airway epithelial cells do not produce significant amounts of IL-1β in response to inflammasome stimulation |
| T44 | 108-203 | Sentence | denotes | The inflammasomes and their respective activators examined in this study are listed in Table 1. |
| T45 | 204-270 | Sentence | denotes | Cells were stimulated in accordance with the schedule in Figure 1. |
| T46 | 271-431 | Sentence | denotes | In CF, airway epithelial cells have been shown to possess a hyper-inflammatory phenotype and produce an exaggerated pro-inflammatory cytokine response [4], [5]. |
| T47 | 432-689 | Sentence | denotes | To determine if airway epithelial cells contribute to the increased IL-1β production in patients with CF, CF and control bronchial epithelial cell lines were stimulated with the inflammasome inducers P. aeruginosa strain PAO1 (PAO1) and LPS followed by ATP. |
| T48 | 690-941 | Sentence | denotes | IL-1β levels in cell culture supernatants were not greatly increased in either the CF or control cell lines (Fig. 2a–d), although a small increase in IL-1β production was detected in NuLi-1 and CuFi-1 cells, but not in S9 and IB3-1 cells, by 24 hours. |
| T49 | 942-1110 | Sentence | denotes | In contrast, these airway cells were highly responsive to other inflammatory stimuli, such as recombinant IL-1β, producing large quantities of IL-8 (Fig. 2a–d inserts). |
| T50 | 1111-1195 | Sentence | denotes | 10.1371/journal.pone.0037689.g001 Figure 1 Cell stimulation and inhibitor schedule. |
| T51 | 1196-1371 | Sentence | denotes | Schedule outlines the timing of inhibitor addition and priming in relation to inflammasome stimulation (t = 0) for THP-1 reporter and PBMC cytokine quantification experiments. |
| T52 | 1372-1477 | Sentence | denotes | Inhibitor treatments and stimulations were carried out as described in the Materials and Methods section. |
| T53 | 1478-1634 | Sentence | denotes | 10.1371/journal.pone.0037689.g002 Figure 2 Airway epithelial cells do not significantly contribute to IL-1β production in response to inflammasome stimuli. |
| T54 | 1635-1882 | Sentence | denotes | Control cell lines ((A) S9, (C) NuLi-1) and their corresponding CF cell lines ((B) IB3-1, and (D) CuFi-1) cells were stimulated with P. aeruginosa (MOI = 10), ATP (5 mM), or IL-1β (10 ng/ml), for the indicated times (n = 3 individual experiments). |
| T55 | 1883-1952 | Sentence | denotes | Cells were primed with LPS (100 ng/ml) for 4 hours where appropriate. |
| T56 | 1953-2031 | Sentence | denotes | Cell culture supernatants were assayed for IL-1β and IL-8 production by ELISA. |
| T57 | 2032-2109 | Sentence | denotes | Insert shows IL-8 secretion in response to stimulation with IL-1β (10 ng/ml). |
| T58 | 2110-2177 | Sentence | denotes | 10.1371/journal.pone.0037689.t001 Table 1 Inflammasome Activators. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 22649552-10970832-88306706 | 423-424 | 10970832 | denotes | 4 |
| 22649552-11404248-88306707 | 428-429 | 11404248 | denotes | 5 |
| T36864 | 423-424 | 10970832 | denotes | 4 |
| T29257 | 428-429 | 11404248 | denotes | 5 |