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PMC:3359311 / 17086-17809 JSONTXT

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bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T14806 90-95 P01584 denotes IL-1β
T14807 287-292 P01584 denotes IL-1β
T14808 301-305 P10145 denotes IL-8
T14809 505-510 P01584 denotes IL-1β
T14810 646-651 P01584 denotes IL-1β
T14811 667-671 P10145 denotes IL-8
T14812 687-691 P05412 denotes AP-1

bionlp-st-ge-2016-reference

Id Subject Object Predicate Lexical cue Negation Speculation
T14661 81-89 Positive_regulation denotes increase true
T14662 90-95 Protein denotes IL-1β
T14663 96-106 Gene_expression denotes production
T14664 287-292 Protein denotes IL-1β
T14665 306-316 Gene_expression denotes production true
T14666 505-510 Protein denotes IL-1β
T14667 511-521 Gene_expression denotes production true
T14668 646-651 Protein denotes IL-1β
T14669 652-661 Localization denotes secretion true
R13025 T14662 T14663 themeOf IL-1β,production
R13026 T14663 T14661 themeOf production,increase
R13027 T14664 T14665 themeOf IL-1β,production
R13028 T14666 T14667 themeOf IL-1β,production
R13029 T14668 T14669 themeOf IL-1β,secretion

bionlp-st-ge-2016-reference-tees

Id Subject Object Predicate Lexical cue
T15001 58-62 Protein denotes CFTR
T15002 90-95 Protein denotes IL-1β
T15003 44-54 Negative_regulation denotes Disruption
T15004 96-106 Gene_expression denotes production
T15005 81-89 Positive_regulation denotes increase
T15006 267-271 Protein denotes PAO1
T15007 447-457 Protein denotes CFTRinh172
T15008 505-510 Protein denotes IL-1β
T15009 511-521 Gene_expression denotes production
T15010 620-624 Protein denotes PAO1
T15011 684-686 Protein denotes κB
T15012 687-691 Protein denotes AP-1
R13332 T15001 T15003 themeOf CFTR,Disruption
R13333 T15002 T15004 themeOf IL-1β,production
R13334 T15003 T15005 causeOf Disruption,increase
R13335 T15004 T15005 themeOf production,increase
R13336 T15008 T15009 themeOf IL-1β,production

events-check-again

Id Subject Object Predicate Lexical cue Negation Speculation
T14992 81-89 Positive_regulation denotes increase true
T14993 90-95 Protein denotes IL-1β
T14994 96-106 Gene_expression denotes production
T14995 287-292 Protein denotes IL-1β
T14996 306-316 Gene_expression denotes production true
T14997 505-510 Protein denotes IL-1β
T14998 511-521 Gene_expression denotes production true
T14999 646-651 Protein denotes IL-1β
T15000 652-661 Localization denotes secretion true
R13327 T14993 T14994 themeOf IL-1β,production
R13328 T14994 T14992 themeOf production,increase
R13329 T14995 T14996 themeOf IL-1β,production
R13330 T14997 T14998 themeOf IL-1β,production
R13331 T14999 T15000 themeOf IL-1β,secretion

GO-CC

Id Subject Object Predicate Lexical cue
T14971 550-555 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

GO-MF

Id Subject Object Predicate Lexical cue
T14972 301-305 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T14973 667-671 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8

GO-BP

Id Subject Object Predicate Lexical cue
T14967 301-316 http://purl.obolibrary.org/obo/GO_0032677 denotes IL-8 production
T14968 301-316 http://purl.obolibrary.org/obo/GO_0032637 denotes IL-8 production
T14969 384-415 http://purl.obolibrary.org/obo/GO_0030225 denotes differentiated into macrophages
T14970 652-661 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T14813 44-54 NN denotes Disruption
T14814 55-57 IN denotes of
T14815 58-62 NNP denotes CFTR
T14816 63-71 NN denotes activity
T14817 72-76 VBZ denotes does
T14818 77-80 RB denotes not
T14819 81-89 VB denotes increase
T14820 90-95 JJ denotes IL-1β
T14821 96-106 NN denotes production
T14822 107-109 IN denotes in
T14823 110-115 NNP denotes PBMCs
T14824 116-118 CC denotes or
T14825 119-130 NNS denotes macrophages
T14826 130-131 . denotes .
T14827 132-137 NNS denotes PBMCs
T14828 138-142 IN denotes from
T14829 143-145 NNP denotes CF
T14830 146-154 NNS denotes patients
T14831 155-156 -LRB- denotes (
T14832 156-157 FW denotes n
T14833 158-159 SYM denotes =
T14834 160-162 CD denotes 15
T14835 162-163 -RRB- denotes )
T14836 164-167 CC denotes and
T14837 168-176 NNS denotes controls
T14838 177-178 -LRB- denotes (
T14839 178-179 FW denotes n
T14840 180-181 SYM denotes =
T14841 182-184 CD denotes 13
T14842 184-185 -RRB- denotes )
T14843 186-190 VBD denotes were
T14844 191-198 VBN denotes treated
T14845 199-203 IN denotes with
T14846 204-214 NNP denotes CFTRinh172
T14847 215-216 -LRB- denotes (
T14848 216-218 CD denotes 10
T14849 219-221 NNP denotes µM
T14850 221-222 -RRB- denotes )
T14851 223-226 IN denotes for
T14852 227-229 CD denotes 18
T14853 230-235 NNS denotes hours
T14854 236-241 RB denotes prior
T14855 242-244 TO denotes to
T14856 245-256 NN denotes stimulation
T14857 257-261 IN denotes with
T14858 262-266 JJ denotes live
T14859 267-271 NNP denotes PAO1
T14860 272-273 -LRB- denotes (
T14861 273-276 NNP denotes MOI
T14862 277-278 SYM denotes =
T14863 279-280 LS denotes 1
T14864 280-281 -RRB- denotes )
T14865 281-282 . denotes .
T14866 283-284 -LRB- denotes (
T14867 284-285 NN denotes A
T14868 285-286 -RRB- denotes )
T14869 287-292 NN denotes IL-1β
T14870 293-296 CC denotes and
T14871 297-298 -LRB- denotes (
T14872 298-299 NNP denotes B
T14873 299-300 -RRB- denotes )
T14874 301-305 JJ denotes IL-8
T14875 306-316 NN denotes production
T14876 317-320 VBD denotes was
T14877 321-329 VBN denotes measured
T14878 330-332 IN denotes at
T14879 333-335 CD denotes 24
T14880 336-341 NNS denotes hours
T14881 341-342 . denotes .
T14882 343-344 -LRB- denotes (
T14883 344-345 $ denotes C
T14884 345-346 -RRB- denotes )
T14885 347-356 NNPS denotes Monocytes
T14886 357-361 IN denotes from
T14887 362-370 NNS denotes controls
T14888 371-372 -LRB- denotes (
T14889 372-373 FW denotes n
T14890 374-375 SYM denotes =
T14891 376-377 LS denotes 3
T14892 377-378 -RRB- denotes )
T14893 379-383 VBD denotes were
T14894 384-398 VBN denotes differentiated
T14895 399-403 IN denotes into
T14896 404-415 NNS denotes macrophages
T14897 415-416 . denotes .
T14898 417-428 NNS denotes Macrophages
T14899 429-433 VBD denotes were
T14900 434-441 VBN denotes treated
T14901 442-446 IN denotes with
T14902 447-457 NNP denotes CFTRinh172
T14903 457-458 , denotes ,
T14904 459-469 VBD denotes stimulated
T14905 470-472 IN denotes as
T14906 473-476 IN denotes per
T14907 477-486 NNS denotes monocytes
T14908 486-487 , denotes ,
T14909 488-491 CC denotes and
T14910 492-500 VBN denotes measured
T14911 501-504 IN denotes for
T14912 505-510 JJ denotes IL-1β
T14913 511-521 NN denotes production
T14914 522-524 IN denotes at
T14915 525-527 CD denotes 24
T14916 528-533 NNS denotes hours
T14917 533-534 . denotes .
T14918 535-540 CD denotes THP-1
T14919 541-549 NN denotes reporter
T14920 550-555 NNS denotes cells
T14921 556-560 VBD denotes were
T14922 561-568 VBN denotes treated
T14923 569-573 IN denotes with
T14924 574-584 NNP denotes CFTRinh172
T14925 585-587 CD denotes 24
T14926 588-593 NNS denotes hours
T14927 594-599 RB denotes prior
T14928 600-602 TO denotes to
T14929 603-614 NN denotes stimulation
T14930 615-619 IN denotes with
T14931 620-624 NNP denotes PAO1
T14932 625-628 CC denotes and
T14933 629-637 VBN denotes measured
T14934 638-641 IN denotes for
T14935 642-643 -LRB- denotes (
T14936 643-644 NNP denotes D
T14937 644-645 -RRB- denotes )
T14938 646-651 JJ denotes IL-1β
T14939 652-661 NN denotes secretion
T14940 661-662 , denotes ,
T14941 663-664 -LRB- denotes (
T14942 664-665 NNP denotes E
T14943 665-666 -RRB- denotes )
T14944 667-671 NN denotes IL-8
T14945 671-672 , denotes ,
T14946 673-676 CC denotes and
T14947 677-678 -LRB- denotes (
T14948 678-679 NN denotes F
T14949 679-680 -RRB- denotes )
T14950 681-686 NN denotes NF-κB
T14951 686-687 NN denotes /
T14952 687-691 NN denotes AP-1
T14953 692-700 NN denotes activity
T14954 701-703 IN denotes at
T14955 704-706 CD denotes 24
T14956 707-712 NNS denotes hours
T14957 713-714 -LRB- denotes (
T14958 714-715 FW denotes n
T14959 716-717 SYM denotes =
T14960 718-719 LS denotes 4
T14961 719-720 -RRB- denotes )
T14962 720-721 . denotes .
R13167 T14813 T14819 nsubj Disruption,increase
R13168 T14814 T14813 prep of,Disruption
R13169 T14815 T14816 amod CFTR,activity
R13170 T14816 T14814 pobj activity,of
R13171 T14817 T14819 aux does,increase
R13172 T14818 T14819 neg not,increase
R13173 T14819 T14819 ROOT increase,increase
R13174 T14820 T14821 amod IL-1β,production
R13175 T14821 T14819 dobj production,increase
R13176 T14822 T14821 prep in,production
R13177 T14823 T14822 pobj PBMCs,in
R13178 T14824 T14823 cc or,PBMCs
R13179 T14825 T14823 conj macrophages,PBMCs
R13180 T14826 T14819 punct .,increase
R13181 T14827 T14844 nsubjpass PBMCs,treated
R13182 T14828 T14827 prep from,PBMCs
R13183 T14829 T14830 compound CF,patients
R13184 T14830 T14828 pobj patients,from
R13185 T14831 T14830 punct (,patients
R13186 T14832 T14834 nmod n,15
R13187 T14833 T14834 punct =,15
R13188 T14834 T14827 appos 15,PBMCs
R13189 T14835 T14827 punct ),PBMCs
R13190 T14836 T14827 cc and,PBMCs
R13191 T14837 T14827 conj controls,PBMCs
R13192 T14838 T14837 punct (,controls
R13193 T14839 T14841 advmod n,13
R13194 T14840 T14841 punct =,13
R13195 T14841 T14837 appos 13,controls
R13196 T14842 T14837 punct ),controls
R13197 T14843 T14844 auxpass were,treated
R13198 T14844 T14844 ROOT treated,treated
R13199 T14845 T14844 prep with,treated
R13200 T14846 T14845 pobj CFTRinh172,with
R13201 T14847 T14849 punct (,µM
R13202 T14848 T14849 nummod 10,µM
R13203 T14849 T14846 appos µM,CFTRinh172
R13204 T14850 T14844 punct ),treated
R13205 T14851 T14844 prep for,treated
R13206 T14852 T14853 nummod 18,hours
R13207 T14853 T14851 pobj hours,for
R13208 T14854 T14844 advmod prior,treated
R13209 T14855 T14854 prep to,prior
R13210 T14856 T14855 pobj stimulation,to
R13211 T14857 T14844 prep with,treated
R13212 T14858 T14859 amod live,PAO1
R13213 T14859 T14857 pobj PAO1,with
R13214 T14860 T14861 punct (,MOI
R13215 T14861 T14859 appos MOI,PAO1
R13216 T14862 T14863 punct =,1
R13217 T14863 T14861 nummod 1,MOI
R13218 T14864 T14863 punct ),1
R13219 T14865 T14844 punct .,treated
R13220 T14866 T14869 punct (,IL-1β
R13221 T14867 T14869 nmod A,IL-1β
R13222 T14868 T14867 punct ),A
R13223 T14869 T14877 nsubjpass IL-1β,measured
R13224 T14870 T14869 cc and,IL-1β
R13225 T14871 T14872 punct (,B
R13226 T14872 T14875 nmod B,production
R13227 T14873 T14872 punct ),B
R13228 T14874 T14875 compound IL-8,production
R13229 T14875 T14869 conj production,IL-1β
R13230 T14876 T14877 auxpass was,measured
R13231 T14877 T14877 ROOT measured,measured
R13232 T14878 T14877 prep at,measured
R13233 T14879 T14880 nummod 24,hours
R13234 T14880 T14878 pobj hours,at
R13235 T14881 T14877 punct .,measured
R13236 T14882 T14883 punct (,C
R13237 T14883 T14883 ROOT C,C
R13238 T14884 T14883 punct ),C
R13239 T14885 T14894 nsubjpass Monocytes,differentiated
R13240 T14886 T14885 prep from,Monocytes
R13241 T14887 T14886 pobj controls,from
R13242 T14888 T14887 punct (,controls
R13243 T14889 T14887 appos n,controls
R13244 T14890 T14887 punct =,controls
R13245 T14891 T14894 nsubjpass 3,differentiated
R13246 T14892 T14891 punct ),3
R13247 T14893 T14894 auxpass were,differentiated
R13248 T14894 T14894 ROOT differentiated,differentiated
R13249 T14895 T14894 prep into,differentiated
R13250 T14896 T14895 pobj macrophages,into
R13251 T14897 T14894 punct .,differentiated
R13252 T14898 T14900 nsubjpass Macrophages,treated
R13253 T14899 T14900 auxpass were,treated
R13254 T14900 T14900 ROOT treated,treated
R13255 T14901 T14900 prep with,treated
R13256 T14902 T14901 pobj CFTRinh172,with
R13257 T14903 T14904 punct ",",stimulated
R13258 T14904 T14900 advcl stimulated,treated
R13259 T14905 T14904 prep as,stimulated
R13260 T14906 T14905 prep per,as
R13261 T14907 T14906 pobj monocytes,per
R13262 T14908 T14904 punct ",",stimulated
R13263 T14909 T14904 cc and,stimulated
R13264 T14910 T14904 conj measured,stimulated
R13265 T14911 T14910 prep for,measured
R13266 T14912 T14913 compound IL-1β,production
R13267 T14913 T14911 pobj production,for
R13268 T14914 T14910 prep at,measured
R13269 T14915 T14916 nummod 24,hours
R13270 T14916 T14914 pobj hours,at
R13271 T14917 T14900 punct .,treated
R13272 T14918 T14920 nummod THP-1,cells
R13273 T14919 T14920 compound reporter,cells
R13274 T14920 T14922 nsubjpass cells,treated
R13275 T14921 T14922 auxpass were,treated
R13276 T14922 T14922 ROOT treated,treated
R13277 T14923 T14922 prep with,treated
R13278 T14924 T14923 pobj CFTRinh172,with
R13279 T14925 T14926 nummod 24,hours
R13280 T14926 T14927 npadvmod hours,prior
R13281 T14927 T14922 advmod prior,treated
R13282 T14928 T14927 prep to,prior
R13283 T14929 T14928 pobj stimulation,to
R13284 T14930 T14922 prep with,treated
R13285 T14931 T14930 pobj PAO1,with
R13286 T14932 T14922 cc and,treated
R13287 T14933 T14922 conj measured,treated
R13288 T14934 T14933 prep for,measured
R13289 T14935 T14936 punct (,D
R13290 T14936 T14934 pobj D,for
R13291 T14937 T14933 punct ),measured
R13292 T14938 T14939 amod IL-1β,secretion
R13293 T14939 T14939 ROOT secretion,secretion
R13294 T14940 T14939 punct ",",secretion
R13295 T14941 T14944 punct (,IL-8
R13296 T14942 T14944 nmod E,IL-8
R13297 T14943 T14944 punct ),IL-8
R13298 T14944 T14939 appos IL-8,secretion
R13299 T14945 T14944 punct ",",IL-8
R13300 T14946 T14944 cc and,IL-8
R13301 T14947 T14948 punct (,F
R13302 T14948 T14950 nmod F,NF-κB
R13303 T14949 T14950 punct ),NF-κB
R13304 T14950 T14944 conj NF-κB,IL-8
R13305 T14951 T14953 nmod /,activity
R13306 T14952 T14953 compound AP-1,activity
R13307 T14953 T14950 dobj activity,NF-κB
R13308 T14954 T14950 prep at,NF-κB
R13309 T14955 T14956 nummod 24,hours
R13310 T14956 T14954 pobj hours,at
R13311 T14957 T14956 punct (,hours
R13312 T14958 T14956 parataxis n,hours
R13313 T14959 T14960 punct =,4
R13314 T14960 T14956 nummod 4,hours
R13315 T14961 T14950 punct ),NF-κB
R13316 T14962 T14922 punct .,treated

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T14739 351-359 NN denotes cytes fr
T14674 44-54 NN denotes Disruption
T14675 55-57 IN denotes of
T14676 58-62 NN denotes CFTR
T14677 63-71 NN denotes activity
T14678 72-76 VB denotes does
T14679 77-80 RB denotes not
T14680 81-89 VB denotes increase
T14681 90-95 NN denotes IL-1β
T14682 96-106 NN denotes production
T14683 107-109 IN denotes in
T14684 110-115 NN denotes PBMCs
T14685 116-118 CC denotes or
T14686 119-130 NN denotes macrophages
T14687 132-137 NN denotes PBMCs
T14688 138-142 IN denotes from
T14689 143-145 NN denotes CF
T14690 146-154 NN denotes patients
T14691 155-156 -LRB- denotes (
T14692 156-162 NN denotes n = 15
T14693 162-163 -RRB- denotes )
T14694 164-167 CC denotes and
T14695 168-176 NN denotes controls
T14696 177-178 -LRB- denotes (
T14697 178-184 NN denotes n = 13
T14698 184-185 -RRB- denotes )
T14699 186-190 VB denotes were
T14700 191-198 VB denotes treated
T14701 199-203 IN denotes with
T14702 204-214 NN denotes CFTRinh172
T14703 215-216 -LRB- denotes (
T14704 216-218 CD denotes 10
T14705 219-221 NN denotes µM
T14706 221-222 -RRB- denotes )
T14707 223-226 IN denotes for
T14708 227-229 CD denotes 18
T14709 230-235 NN denotes hours
T14710 236-241 RB denotes prior
T14711 242-244 TO denotes to
T14712 245-256 NN denotes stimulation
T14713 257-261 IN denotes with
T14714 262-266 JJ denotes live
T14715 267-271 NN denotes PAO1
T14716 272-273 -LRB- denotes (
T14717 273-280 NN denotes MOI = 1
T14718 280-281 -RRB- denotes )
T14719 281-282 -LRB- denotes .
T14720 283-284 NN denotes (
T14721 284-285 -RRB- denotes A
T14722 285-290 NN denotes ) IL-
T14723 290-293 CC denotes 1β
T14724 293-294 -LRB- denotes a
T14725 294-295 NN denotes n
T14726 295-296 -RRB- denotes d
T14727 297-301 NN denotes (B)
T14728 301-311 NN denotes IL-8 produ
T14729 311-314 VB denotes cti
T14730 314-322 VB denotes on was m
T14731 322-324 IN denotes ea
T14732 324-326 CD denotes su
T14733 326-332 NN denotes red at
T14734 333-334 -LRB- denotes 2
T14735 334-335 NN denotes 4
T14736 336-337 -RRB- denotes h
T14737 337-346 NN denotes ours. (C)
T14738 347-351 IN denotes Mono
T14740 359-360 -LRB- denotes o
T14741 360-365 NN denotes m con
T14742 365-366 -RRB- denotes t
T14743 366-370 VB denotes rols
T14744 371-385 VB denotes (n = 3) were d
T14745 385-389 IN denotes iffe
T14746 389-400 NN denotes rentiated i
T14747 417-428 NN denotes Macrophages
T14748 429-433 VB denotes were
T14749 434-441 VB denotes treated
T14750 442-446 IN denotes with
T14751 447-457 NN denotes CFTRinh172
T14752 457-458 -COMMA- denotes ,
T14753 459-469 VB denotes stimulated
T14754 470-472 IN denotes as
T14755 473-476 IN denotes per
T14756 477-486 NN denotes monocytes
T14757 486-487 -COMMA- denotes ,
T14758 488-491 CC denotes and
T14759 492-500 VB denotes measured
T14760 501-504 IN denotes for
T14761 505-510 NN denotes IL-1β
T14762 511-521 NN denotes production
T14763 522-524 IN denotes at
T14764 525-527 CD denotes 24
T14765 528-533 NN denotes hours
T14766 535-540 NN denotes THP-1
T14767 541-549 NN denotes reporter
T14768 550-555 NN denotes cells
T14769 556-560 VB denotes were
T14770 561-568 VB denotes treated
T14771 569-573 IN denotes with
T14772 574-584 NN denotes CFTRinh172
T14773 585-587 CD denotes 24
T14774 588-593 NN denotes hours
T14775 594-599 RB denotes prior
T14776 600-602 TO denotes to
T14777 603-614 NN denotes stimulation
T14778 615-619 IN denotes with
T14779 620-624 NN denotes PAO1
T14780 625-628 CC denotes and
T14781 629-637 VB denotes measured
T14782 638-641 IN denotes for
T14783 642-643 -LRB- denotes (
T14784 643-644 NN denotes D
T14785 644-645 -RRB- denotes )
T14786 646-651 NN denotes IL-1β
T14787 652-661 NN denotes secretion
T14788 661-662 -COMMA- denotes ,
T14789 663-664 -LRB- denotes (
T14790 664-665 NN denotes E
T14791 665-666 -RRB- denotes )
T14792 667-671 NN denotes IL-8
T14793 671-672 -COMMA- denotes ,
T14794 673-676 CC denotes and
T14795 677-678 -LRB- denotes (
T14796 678-679 NN denotes F
T14797 679-680 -RRB- denotes )
T14798 681-691 NN denotes NF-κB/AP-1
T14799 692-700 NN denotes activity
T14800 701-703 IN denotes at
T14801 704-706 CD denotes 24
T14802 707-712 NN denotes hours
T14803 713-714 -LRB- denotes (
T14804 714-719 NN denotes n = 4
T14805 719-720 -RRB- denotes )
R13030 T14674 T14675 arg1Of Disruption,of
R13031 T14674 T14678 arg1Of Disruption,does
R13032 T14674 T14680 arg1Of Disruption,increase
R13033 T14677 T14675 arg2Of activity,of
R13034 T14677 T14676 arg1Of activity,CFTR
R13035 T14680 T14678 arg2Of increase,does
R13036 T14680 T14679 arg1Of increase,not
R13037 T14682 T14680 arg2Of production,increase
R13038 T14682 T14681 arg1Of production,IL-1β
R13039 T14682 T14683 arg1Of production,in
R13040 T14684 T14685 arg1Of PBMCs,or
R13041 T14685 T14683 arg2Of or,in
R13042 T14686 T14685 arg2Of macrophages,or
R13043 T14687 T14688 arg1Of PBMCs,from
R13044 T14687 T14699 arg1Of PBMCs,were
R13045 T14687 T14700 arg2Of PBMCs,treated
R13046 T14687 T14743 arg1Of PBMCs,rols
R13047 T14687 T14744 arg2Of PBMCs,(n = 3) were d
R13048 T14690 T14689 arg1Of patients,CF
R13049 T14690 T14691 arg1Of patients,(
R13050 T14690 T14694 arg1Of patients,and
R13051 T14692 T14691 arg2Of n = 15,(
R13052 T14693 T14691 arg3Of ),(
R13053 T14694 T14688 arg2Of and,from
R13054 T14695 T14694 arg2Of controls,and
R13055 T14695 T14696 arg1Of controls,(
R13056 T14697 T14696 arg2Of n = 13,(
R13057 T14698 T14696 arg3Of ),(
R13058 T14700 T14699 arg2Of treated,were
R13059 T14700 T14701 arg1Of treated,with
R13060 T14700 T14723 arg1Of treated,1β
R13061 T14702 T14701 arg2Of CFTRinh172,with
R13062 T14702 T14703 arg1Of CFTRinh172,(
R13063 T14702 T14707 arg1Of CFTRinh172,for
R13064 T14702 T14711 arg1Of CFTRinh172,to
R13065 T14705 T14703 arg2Of µM,(
R13066 T14705 T14704 arg1Of µM,10
R13067 T14706 T14703 arg3Of ),(
R13068 T14709 T14707 arg2Of hours,for
R13069 T14709 T14708 arg1Of hours,18
R13070 T14711 T14710 arg1Of to,prior
R13071 T14712 T14711 arg2Of stimulation,to
R13072 T14712 T14713 arg1Of stimulation,with
R13073 T14715 T14714 arg1Of PAO1,live
R13074 T14715 T14716 arg1Of PAO1,(
R13075 T14715 T14719 arg1Of PAO1,.
R13076 T14717 T14716 arg2Of MOI = 1,(
R13077 T14718 T14716 arg3Of ),(
R13078 T14720 T14719 arg2Of (,.
R13079 T14721 T14719 arg3Of A,.
R13080 T14722 T14713 arg2Of ) IL-,with
R13081 T14722 T14715 arg1Of ) IL-,PAO1
R13082 T14725 T14724 arg2Of n,a
R13083 T14726 T14724 arg3Of d,a
R13084 T14728 T14724 arg1Of IL-8 produ,a
R13085 T14728 T14727 arg1Of IL-8 produ,(B)
R13086 T14728 T14729 arg1Of IL-8 produ,cti
R13087 T14728 T14730 arg2Of IL-8 produ,on was m
R13088 T14730 T14729 arg2Of on was m,cti
R13089 T14730 T14731 arg1Of on was m,ea
R13090 T14735 T14734 arg2Of 4,2
R13091 T14736 T14734 arg3Of h,2
R13092 T14737 T14731 arg2Of ours. (C),ea
R13093 T14737 T14732 arg1Of ours. (C),su
R13094 T14737 T14733 arg1Of ours. (C),red at
R13095 T14737 T14734 arg1Of ours. (C),2
R13096 T14737 T14738 arg1Of ours. (C),Mono
R13097 T14739 T14738 arg2Of cytes fr,Mono
R13098 T14739 T14740 arg1Of cytes fr,o
R13099 T14741 T14740 arg2Of m con,o
R13100 T14742 T14740 arg3Of t,o
R13101 T14744 T14723 arg2Of (n = 3) were d,1β
R13102 T14744 T14729 modOf (n = 3) were d,cti
R13103 T14744 T14743 arg2Of (n = 3) were d,rols
R13104 T14744 T14745 arg1Of (n = 3) were d,iffe
R13105 T14746 T14745 arg2Of rentiated i,iffe
R13106 T14747 T14748 arg1Of Macrophages,were
R13107 T14747 T14749 arg2Of Macrophages,treated
R13108 T14749 T14748 arg2Of treated,were
R13109 T14749 T14750 arg1Of treated,with
R13110 T14751 T14750 arg2Of CFTRinh172,with
R13111 T14751 T14752 arg1Of CFTRinh172,","
R13112 T14751 T14753 arg2Of CFTRinh172,stimulated
R13113 T14751 T14759 arg2Of CFTRinh172,measured
R13114 T14753 T14755 arg1Of stimulated,per
R13115 T14753 T14758 arg1Of stimulated,and
R13116 T14755 T14754 arg1Of per,as
R13117 T14756 T14755 arg2Of monocytes,per
R13118 T14758 T14757 arg1Of and,","
R13119 T14759 T14758 arg2Of measured,and
R13120 T14759 T14760 arg1Of measured,for
R13121 T14759 T14763 arg1Of measured,at
R13122 T14762 T14760 arg2Of production,for
R13123 T14762 T14761 arg1Of production,IL-1β
R13124 T14765 T14763 arg2Of hours,at
R13125 T14765 T14764 arg1Of hours,24
R13126 T14768 T14766 arg1Of cells,THP-1
R13127 T14768 T14767 arg1Of cells,reporter
R13128 T14768 T14769 arg1Of cells,were
R13129 T14768 T14770 arg2Of cells,treated
R13130 T14768 T14781 arg2Of cells,measured
R13131 T14770 T14771 arg1Of treated,with
R13132 T14770 T14775 arg1Of treated,prior
R13133 T14770 T14780 arg1Of treated,and
R13134 T14772 T14771 arg2Of CFTRinh172,with
R13135 T14774 T14773 arg1Of hours,24
R13136 T14775 T14774 arg1Of prior,hours
R13137 T14775 T14776 arg1Of prior,to
R13138 T14777 T14776 arg2Of stimulation,to
R13139 T14777 T14778 arg1Of stimulation,with
R13140 T14779 T14778 arg2Of PAO1,with
R13141 T14780 T14769 arg2Of and,were
R13142 T14781 T14780 arg2Of measured,and
R13143 T14781 T14782 arg1Of measured,for
R13144 T14784 T14783 arg2Of D,(
R13145 T14785 T14783 arg3Of ),(
R13146 T14787 T14783 arg1Of secretion,(
R13147 T14787 T14786 arg1Of secretion,IL-1β
R13148 T14787 T14788 arg1Of secretion,","
R13149 T14788 T14794 arg1Of ",",and
R13150 T14790 T14789 arg2Of E,(
R13151 T14791 T14789 arg3Of ),(
R13152 T14792 T14788 arg2Of IL-8,","
R13153 T14792 T14789 arg1Of IL-8,(
R13154 T14794 T14782 arg2Of and,for
R13155 T14794 T14793 arg1Of and,","
R13156 T14796 T14795 arg2Of F,(
R13157 T14797 T14795 arg3Of ),(
R13158 T14799 T14794 arg2Of activity,and
R13159 T14799 T14795 arg1Of activity,(
R13160 T14799 T14798 arg1Of activity,NF-κB/AP-1
R13161 T14799 T14800 arg1Of activity,at
R13162 T14802 T14800 arg2Of hours,at
R13163 T14802 T14801 arg1Of hours,24
R13164 T14802 T14803 arg1Of hours,(
R13165 T14804 T14803 arg2Of n = 4,(
R13166 T14805 T14803 arg3Of ),(

sentences

Id Subject Object Predicate Lexical cue
T14670 44-131 Sentence denotes Disruption of CFTR activity does not increase IL-1β production in PBMCs or macrophages.
T14671 132-416 Sentence denotes PBMCs from CF patients (n = 15) and controls (n = 13) were treated with CFTRinh172 (10 µM) for 18 hours prior to stimulation with live PAO1 (MOI = 1). (A) IL-1β and (B) IL-8 production was measured at 24 hours. (C) Monocytes from controls (n = 3) were differentiated into macrophages.
T14672 417-534 Sentence denotes Macrophages were treated with CFTRinh172, stimulated as per monocytes, and measured for IL-1β production at 24 hours.
T14673 535-721 Sentence denotes THP-1 reporter cells were treated with CFTRinh172 24 hours prior to stimulation with PAO1 and measured for (D) IL-1β secretion, (E) IL-8, and (F) NF-κB/AP-1 activity at 24 hours (n = 4).
T119 0-131 Sentence denotes 10.1371/journal.pone.0037689.g008 Figure 8 Disruption of CFTR activity does not increase IL-1β production in PBMCs or macrophages.
T120 132-416 Sentence denotes PBMCs from CF patients (n = 15) and controls (n = 13) were treated with CFTRinh172 (10 µM) for 18 hours prior to stimulation with live PAO1 (MOI = 1). (A) IL-1β and (B) IL-8 production was measured at 24 hours. (C) Monocytes from controls (n = 3) were differentiated into macrophages.
T121 417-534 Sentence denotes Macrophages were treated with CFTRinh172, stimulated as per monocytes, and measured for IL-1β production at 24 hours.
T122 535-721 Sentence denotes THP-1 reporter cells were treated with CFTRinh172 24 hours prior to stimulation with PAO1 and measured for (D) IL-1β secretion, (E) IL-8, and (F) NF-κB/AP-1 activity at 24 hours (n = 4).