PMC:3342329 / 1358-1662 JSONTXT

{"project":"test3","denotations":[{"id":"T110","span":{"begin":283,"end":293},"obj":"Negative_regulation"},{"id":"T109","span":{"begin":219,"end":223},"obj":"Protein"},{"id":"T108","span":{"begin":168,"end":172},"obj":"Protein"},{"id":"T107","span":{"begin":135,"end":139},"obj":"Protein"},{"id":"T79","span":{"begin":219,"end":223},"obj":"Protein"},{"id":"T78","span":{"begin":168,"end":172},"obj":"Protein"},{"id":"T77","span":{"begin":135,"end":139},"obj":"Protein"}],"text":"nfiltration of CD8+ cytotoxic T cell and CD57+ natural killer cells was significantly increased in melanoma tumor and spleen tissue of CCR5−/− mice compared to that of CCR5+/+ mice. Therefore, these results showed that CCR5 deficiency caused apoptotic cell death of melanoma through inhibition of NF-κB a"}

{"project":"testone","denotations":[{"id":"T41","span":{"begin":135,"end":139},"obj":"Protein"},{"id":"T57","span":{"begin":283,"end":293},"obj":"Negative_regulation"},{"id":"T56","span":{"begin":224,"end":234},"obj":"Negative_regulation"},{"id":"T43","span":{"begin":219,"end":223},"obj":"Protein"},{"id":"T42","span":{"begin":168,"end":172},"obj":"Protein"}],"relations":[{"id":"R9","pred":"themeOf","subj":"T43","obj":"T56"}],"text":"nfiltration of CD8+ cytotoxic T cell and CD57+ natural killer cells was significantly increased in melanoma tumor and spleen tissue of CCR5−/− mice compared to that of CCR5+/+ mice. Therefore, these results showed that CCR5 deficiency caused apoptotic cell death of melanoma through inhibition of NF-κB a"}

{"project":"BioNLP16_Messiy","denotations":[{"id":"T646","span":{"begin":224,"end":234},"obj":"Negative_regulation"},{"id":"T635","span":{"begin":219,"end":223},"obj":"Protein"},{"id":"T634","span":{"begin":168,"end":172},"obj":"Protein"},{"id":"T633","span":{"begin":135,"end":139},"obj":"Protein"}],"relations":[{"id":"R347","pred":"themeOf","subj":"T635","obj":"T646"}],"text":"nfiltration of CD8+ cytotoxic T cell and CD57+ natural killer cells was significantly increased in melanoma tumor and spleen tissue of CCR5−/− mice compared to that of CCR5+/+ mice. Therefore, these results showed that CCR5 deficiency caused apoptotic cell death of melanoma through inhibition of NF-κB a"}

{"project":"BioNLP16_DUT","denotations":[{"id":"T772","span":{"begin":224,"end":234},"obj":"Negative_regulation"},{"id":"T761","span":{"begin":219,"end":223},"obj":"Protein"},{"id":"T760","span":{"begin":168,"end":172},"obj":"Protein"},{"id":"T759","span":{"begin":135,"end":139},"obj":"Protein"}],"relations":[{"id":"R416","pred":"themeOf","subj":"T761","obj":"T772"}],"text":"nfiltration of CD8+ cytotoxic T cell and CD57+ natural killer cells was significantly increased in melanoma tumor and spleen tissue of CCR5−/− mice compared to that of CCR5+/+ mice. Therefore, these results showed that CCR5 deficiency caused apoptotic cell death of melanoma through inhibition of NF-κB a"}

{"project":"pmc-enju-pas","denotations":[{"id":"T526","span":{"begin":297,"end":302},"obj":"NN"},{"id":"T525","span":{"begin":294,"end":296},"obj":"IN"},{"id":"T524","span":{"begin":283,"end":293},"obj":"NN"},{"id":"T523","span":{"begin":275,"end":282},"obj":"IN"},{"id":"T522","span":{"begin":266,"end":274},"obj":"NN"},{"id":"T521","span":{"begin":263,"end":265},"obj":"IN"},{"id":"T520","span":{"begin":257,"end":262},"obj":"NN"},{"id":"T519","span":{"begin":252,"end":256},"obj":"NN"},{"id":"T518","span":{"begin":242,"end":251},"obj":"JJ"},{"id":"T517","span":{"begin":235,"end":241},"obj":"VB"},{"id":"T516","span":{"begin":224,"end":234},"obj":"NN"},{"id":"T515","span":{"begin":219,"end":223},"obj":"NN"},{"id":"T514","span":{"begin":214,"end":218},"obj":"IN"},{"id":"T513","span":{"begin":207,"end":213},"obj":"VB"},{"id":"T512","span":{"begin":199,"end":206},"obj":"NN"},{"id":"T511","span":{"begin":193,"end":198},"obj":"DT"},{"id":"T510","span":{"begin":191,"end":192},"obj":"-COMMA-"},{"id":"T509","span":{"begin":182,"end":191},"obj":"RB"},{"id":"T508","span":{"begin":176,"end":180},"obj":"NN"},{"id":"T507","span":{"begin":168,"end":175},"obj":"JJ"},{"id":"T506","span":{"begin":165,"end":167},"obj":"IN"},{"id":"T505","span":{"begin":160,"end":164},"obj":"DT"},{"id":"T504","span":{"begin":157,"end":159},"obj":"TO"},{"id":"T503","span":{"begin":148,"end":156},"obj":"VB"},{"id":"T502","span":{"begin":143,"end":147},"obj":"NN"},{"id":"T501","span":{"begin":135,"end":142},"obj":"NN"},{"id":"T500","span":{"begin":132,"end":134},"obj":"IN"},{"id":"T499","span":{"begin":125,"end":131},"obj":"NN"},{"id":"T498","span":{"begin":118,"end":124},"obj":"NN"},{"id":"T497","span":{"begin":114,"end":117},"obj":"CC"},{"id":"T496","span":{"begin":108,"end":113},"obj":"NN"},{"id":"T495","span":{"begin":99,"end":107},"obj":"NN"},{"id":"T494","span":{"begin":96,"end":98},"obj":"IN"},{"id":"T493","span":{"begin":86,"end":95},"obj":"VB"},{"id":"T492","span":{"begin":72,"end":85},"obj":"RB"},{"id":"T491","span":{"begin":68,"end":71},"obj":"VB"},{"id":"T490","span":{"begin":62,"end":67},"obj":"NN"},{"id":"T489","span":{"begin":55,"end":61},"obj":"NN"},{"id":"T488","span":{"begin":47,"end":54},"obj":"JJ"},{"id":"T487","span":{"begin":41,"end":46},"obj":"JJ"},{"id":"T486","span":{"begin":37,"end":40},"obj":"CC"},{"id":"T485","span":{"begin":32,"end":36},"obj":"NN"},{"id":"T484","span":{"begin":30,"end":31},"obj":"NN"},{"id":"T483","span":{"begin":20,"end":29},"obj":"JJ"},{"id":"T482","span":{"begin":15,"end":19},"obj":"JJ"},{"id":"T481","span":{"begin":12,"end":14},"obj":"IN"}],"relations":[{"id":"R263","pred":"arg1Of","subj":"T485","obj":"T482"},{"id":"R264","pred":"arg1Of","subj":"T485","obj":"T483"},{"id":"R265","pred":"arg1Of","subj":"T485","obj":"T484"},{"id":"R266","pred":"arg1Of","subj":"T485","obj":"T486"},{"id":"R267","pred":"arg2Of","subj":"T486","obj":"T481"},{"id":"R268","pred":"arg2Of","subj":"T490","obj":"T486"},{"id":"R269","pred":"arg1Of","subj":"T490","obj":"T487"},{"id":"R270","pred":"arg1Of","subj":"T490","obj":"T488"},{"id":"R271","pred":"arg1Of","subj":"T490","obj":"T489"},{"id":"R274","pred":"arg2Of","subj":"T493","obj":"T491"},{"id":"R275","pred":"arg1Of","subj":"T493","obj":"T492"},{"id":"R276","pred":"arg1Of","subj":"T493","obj":"T494"},{"id":"R277","pred":"arg1Of","subj":"T496","obj":"T497"},{"id":"R278","pred":"arg2Of","subj":"T498","obj":"T497"},{"id":"R279","pred":"arg2Of","subj":"T499","obj":"T494"},{"id":"R280","pred":"arg1Of","subj":"T499","obj":"T495"},{"id":"R281","pred":"arg1Of","subj":"T499","obj":"T496"},{"id":"R282","pred":"arg1Of","subj":"T499","obj":"T498"},{"id":"R283","pred":"arg1Of","subj":"T499","obj":"T500"},{"id":"R284","pred":"arg2Of","subj":"T502","obj":"T500"},{"id":"R285","pred":"arg1Of","subj":"T502","obj":"T501"},{"id":"R286","pred":"arg2Of","subj":"T502","obj":"T503"},{"id":"R287","pred":"arg1Of","subj":"T503","obj":"T504"},{"id":"R288","pred":"arg2Of","subj":"T505","obj":"T504"},{"id":"R289","pred":"arg1Of","subj":"T505","obj":"T506"},{"id":"R290","pred":"arg2Of","subj":"T508","obj":"T506"},{"id":"R291","pred":"arg1Of","subj":"T508","obj":"T507"},{"id":"R292","pred":"arg1Of","subj":"T512","obj":"T511"},{"id":"R293","pred":"arg1Of","subj":"T512","obj":"T513"},{"id":"R294","pred":"arg1Of","subj":"T513","obj":"T509"},{"id":"R295","pred":"arg1Of","subj":"T513","obj":"T510"},{"id":"R296","pred":"arg1Of","subj":"T516","obj":"T515"},{"id":"R297","pred":"arg1Of","subj":"T516","obj":"T517"},{"id":"R298","pred":"arg2Of","subj":"T517","obj":"T513"},{"id":"R299","pred":"arg1Of","subj":"T517","obj":"T514"},{"id":"R300","pred":"arg1Of","subj":"T517","obj":"T523"},{"id":"R301","pred":"arg2Of","subj":"T520","obj":"T517"},{"id":"R302","pred":"arg1Of","subj":"T520","obj":"T518"},{"id":"R303","pred":"arg1Of","subj":"T520","obj":"T519"},{"id":"R304","pred":"arg1Of","subj":"T520","obj":"T521"},{"id":"R305","pred":"arg2Of","subj":"T522","obj":"T521"},{"id":"R306","pred":"arg2Of","subj":"T524","obj":"T523"},{"id":"R307","pred":"arg1Of","subj":"T524","obj":"T525"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"text":"nfiltration of CD8+ cytotoxic T cell and CD57+ natural killer cells was significantly increased in melanoma tumor and spleen tissue of CCR5−/− mice compared to that of CCR5+/+ mice. Therefore, these results showed that CCR5 deficiency caused apoptotic cell death of melanoma through inhibition of NF-κB a"}

{"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T185","span":{"begin":219,"end":223},"obj":"Protein"},{"id":"T184","span":{"begin":168,"end":172},"obj":"Protein"},{"id":"T183","span":{"begin":135,"end":139},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"nfiltration of CD8+ cytotoxic T cell and CD57+ natural killer cells was significantly increased in melanoma tumor and spleen tissue of CCR5−/− mice compared to that of CCR5+/+ mice. Therefore, these results showed that CCR5 deficiency caused apoptotic cell death of melanoma through inhibition of NF-κB a"}

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T554","span":{"begin":15,"end":18},"obj":"http://www.uniprot.org/uniprot/P10966"},{"id":"T553","span":{"begin":15,"end":18},"obj":"http://www.uniprot.org/uniprot/P01732"},{"id":"T547","span":{"begin":219,"end":223},"obj":"http://www.uniprot.org/uniprot/P51681"},{"id":"T546","span":{"begin":168,"end":172},"obj":"http://www.uniprot.org/uniprot/P51681"},{"id":"T545","span":{"begin":135,"end":139},"obj":"http://www.uniprot.org/uniprot/P51681"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"nfiltration of CD8+ cytotoxic T cell and CD57+ natural killer cells was significantly increased in melanoma tumor and spleen tissue of CCR5−/− mice compared to that of CCR5+/+ mice. Therefore, these results showed that CCR5 deficiency caused apoptotic cell death of melanoma through inhibition of NF-κB a"}

{"project":"UBERON-AE","denotations":[{"id":"T119","span":{"begin":118,"end":124},"obj":"http://purl.obolibrary.org/obo/UBERON_0002106"},{"id":"T117","span":{"begin":125,"end":131},"obj":"http://purl.obolibrary.org/obo/UBERON_0000479"}],"text":"nfiltration of CD8+ cytotoxic T cell and CD57+ natural killer cells was significantly increased in melanoma tumor and spleen tissue of CCR5−/− mice compared to that of CCR5+/+ mice. Therefore, these results showed that CCR5 deficiency caused apoptotic cell death of melanoma through inhibition of NF-κB a"}

{"project":"GO-BP","denotations":[{"id":"T209","span":{"begin":257,"end":262},"obj":"http://purl.obolibrary.org/obo/GO_0016265"},{"id":"T208","span":{"begin":252,"end":262},"obj":"http://purl.obolibrary.org/obo/GO_0008219"},{"id":"T199","span":{"begin":242,"end":262},"obj":"http://purl.obolibrary.org/obo/GO_0006915"}],"text":"nfiltration of CD8+ cytotoxic T cell and CD57+ natural killer cells was significantly increased in melanoma tumor and spleen tissue of CCR5−/− mice compared to that of CCR5+/+ mice. Therefore, these results showed that CCR5 deficiency caused apoptotic cell death of melanoma through inhibition of NF-κB a"}

{"project":"GO-CC","denotations":[{"id":"T211","span":{"begin":32,"end":36},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T212","span":{"begin":252,"end":256},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"nfiltration of CD8+ cytotoxic T cell and CD57+ natural killer cells was significantly increased in melanoma tumor and spleen tissue of CCR5−/− mice compared to that of CCR5+/+ mice. Therefore, these results showed that CCR5 deficiency caused apoptotic cell death of melanoma through inhibition of NF-κB a"}

{"project":"simple1","denotations":[{"id":"T258","span":{"begin":219,"end":223},"obj":"Protein"},{"id":"T257","span":{"begin":168,"end":172},"obj":"Protein"},{"id":"T256","span":{"begin":135,"end":139},"obj":"Protein"}],"text":"nfiltration of CD8+ cytotoxic T cell and CD57+ natural killer cells was significantly increased in melanoma tumor and spleen tissue of CCR5−/− mice compared to that of CCR5+/+ mice. Therefore, these results showed that CCR5 deficiency caused apoptotic cell death of melanoma through inhibition of NF-κB a"}

{"project":"DLUT931","denotations":[{"id":"T587","span":{"begin":283,"end":293},"obj":"Negative_regulation"},{"id":"T585","span":{"begin":224,"end":234},"obj":"Negative_regulation"},{"id":"T575","span":{"begin":219,"end":223},"obj":"Protein"},{"id":"T574","span":{"begin":168,"end":172},"obj":"Protein"},{"id":"T573","span":{"begin":135,"end":139},"obj":"Protein"}],"relations":[{"id":"R322","pred":"themeOf","subj":"T575","obj":"T585"},{"id":"R328","pred":"causeOf","subj":"T585","obj":"T587"}],"text":"nfiltration of CD8+ cytotoxic T cell and CD57+ natural killer cells was significantly increased in melanoma tumor and spleen tissue of CCR5−/− mice compared to that of CCR5+/+ mice. Therefore, these results showed that CCR5 deficiency caused apoptotic cell death of melanoma through inhibition of NF-κB a"}

{"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T803","span":{"begin":176,"end":180},"obj":"Protein"},{"id":"T789","span":{"begin":168,"end":172},"obj":"Protein"},{"id":"T788","span":{"begin":297,"end":302},"obj":"Protein"},{"id":"T785","span":{"begin":143,"end":147},"obj":"Protein"},{"id":"T783","span":{"begin":41,"end":67},"obj":"Entity"},{"id":"T781","span":{"begin":219,"end":234},"obj":"Protein"},{"id":"T776","span":{"begin":15,"end":36},"obj":"Entity"}],"text":"nfiltration of CD8+ cytotoxic T cell and CD57+ natural killer cells was significantly increased in melanoma tumor and spleen tissue of CCR5−/− mice compared to that of CCR5+/+ mice. Therefore, these results showed that CCR5 deficiency caused apoptotic cell death of melanoma through inhibition of NF-κB a"}

{"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T1130","span":{"begin":297,"end":302},"obj":"NNP"},{"id":"T1129","span":{"begin":294,"end":296},"obj":"IN"},{"id":"T1128","span":{"begin":283,"end":293},"obj":"NN"},{"id":"T1127","span":{"begin":275,"end":282},"obj":"IN"},{"id":"T1126","span":{"begin":266,"end":274},"obj":"NN"},{"id":"T1125","span":{"begin":263,"end":265},"obj":"IN"},{"id":"T1124","span":{"begin":257,"end":262},"obj":"NN"},{"id":"T1123","span":{"begin":252,"end":256},"obj":"NN"},{"id":"T1122","span":{"begin":242,"end":251},"obj":"JJ"},{"id":"T1121","span":{"begin":235,"end":241},"obj":"VBD"},{"id":"T1120","span":{"begin":224,"end":234},"obj":"NN"},{"id":"T1119","span":{"begin":219,"end":223},"obj":"CD"},{"id":"T1118","span":{"begin":214,"end":218},"obj":"IN"},{"id":"T1117","span":{"begin":207,"end":213},"obj":"VBD"},{"id":"T1116","span":{"begin":199,"end":206},"obj":"NNS"},{"id":"T1115","span":{"begin":193,"end":198},"obj":"DT"},{"id":"T1114","span":{"begin":191,"end":192},"obj":","},{"id":"T1113","span":{"begin":182,"end":191},"obj":"RB"},{"id":"T1112","span":{"begin":180,"end":181},"obj":"."},{"id":"T1111","span":{"begin":176,"end":180},"obj":"NNS"},{"id":"T1110","span":{"begin":174,"end":175},"obj":"NN"},{"id":"T1109","span":{"begin":173,"end":174},"obj":"NN"},{"id":"T1108","span":{"begin":172,"end":173},"obj":"CD"},{"id":"T1107","span":{"begin":168,"end":172},"obj":"CD"},{"id":"T1106","span":{"begin":165,"end":167},"obj":"IN"},{"id":"T1105","span":{"begin":160,"end":164},"obj":"DT"},{"id":"T1104","span":{"begin":157,"end":159},"obj":"TO"},{"id":"T1103","span":{"begin":148,"end":156},"obj":"VBN"},{"id":"T1102","span":{"begin":143,"end":147},"obj":"NNS"},{"id":"T1101","span":{"begin":141,"end":142},"obj":"NN"},{"id":"T1100","span":{"begin":140,"end":141},"obj":"NN"},{"id":"T1099","span":{"begin":139,"end":140},"obj":"CD"},{"id":"T1098","span":{"begin":135,"end":139},"obj":"CD"},{"id":"T1097","span":{"begin":132,"end":134},"obj":"IN"},{"id":"T1096","span":{"begin":125,"end":131},"obj":"NN"},{"id":"T1095","span":{"begin":118,"end":124},"obj":"NN"},{"id":"T1094","span":{"begin":114,"end":117},"obj":"CC"},{"id":"T1093","span":{"begin":108,"end":113},"obj":"NN"},{"id":"T1092","span":{"begin":99,"end":107},"obj":"NN"},{"id":"T1091","span":{"begin":96,"end":98},"obj":"IN"},{"id":"T1090","span":{"begin":86,"end":95},"obj":"VBN"},{"id":"T1089","span":{"begin":72,"end":85},"obj":"RB"},{"id":"T1088","span":{"begin":68,"end":71},"obj":"VBD"},{"id":"T1087","span":{"begin":62,"end":67},"obj":"NNS"},{"id":"T1086","span":{"begin":55,"end":61},"obj":"NN"},{"id":"T1085","span":{"begin":47,"end":54},"obj":"JJ"},{"id":"T1084","span":{"begin":45,"end":46},"obj":"VBP"},{"id":"T1083","span":{"begin":41,"end":45},"obj":"NNP"},{"id":"T1082","span":{"begin":37,"end":40},"obj":"CC"},{"id":"T1081","span":{"begin":32,"end":36},"obj":"NN"},{"id":"T1080","span":{"begin":30,"end":31},"obj":"NNP"},{"id":"T1079","span":{"begin":20,"end":29},"obj":"JJ"},{"id":"T1078","span":{"begin":18,"end":19},"obj":"CD"},{"id":"T1077","span":{"begin":15,"end":18},"obj":"CD"},{"id":"T1076","span":{"begin":12,"end":14},"obj":"IN"}],"relations":[{"id":"R628","pred":"pobj","subj":"T1130","obj":"T1129"},{"id":"R683","pred":"nummod","subj":"T1077","obj":"T1081"},{"id":"R684","pred":"nummod","subj":"T1078","obj":"T1081"},{"id":"R685","pred":"amod","subj":"T1079","obj":"T1081"},{"id":"R686","pred":"compound","subj":"T1080","obj":"T1081"},{"id":"R687","pred":"pobj","subj":"T1081","obj":"T1076"},{"id":"R688","pred":"cc","subj":"T1082","obj":"T1081"},{"id":"R689","pred":"nmod","subj":"T1083","obj":"T1084"},{"id":"R690","pred":"mark","subj":"T1084","obj":"T1090"},{"id":"R691","pred":"amod","subj":"T1085","obj":"T1087"},{"id":"R692","pred":"compound","subj":"T1086","obj":"T1087"},{"id":"R693","pred":"nsubjpass","subj":"T1087","obj":"T1090"},{"id":"R695","pred":"auxpass","subj":"T1088","obj":"T1090"},{"id":"R696","pred":"advmod","subj":"T1089","obj":"T1090"},{"id":"R697","pred":"ROOT","subj":"T1090","obj":"T1090"},{"id":"R698","pred":"prep","subj":"T1091","obj":"T1090"},{"id":"R700","pred":"compound","subj":"T1092","obj":"T1093"},{"id":"R701","pred":"pobj","subj":"T1093","obj":"T1091"},{"id":"R702","pred":"cc","subj":"T1094","obj":"T1093"},{"id":"R704","pred":"compound","subj":"T1095","obj":"T1096"},{"id":"R705","pred":"conj","subj":"T1096","obj":"T1093"},{"id":"R706","pred":"prep","subj":"T1097","obj":"T1096"},{"id":"R707","pred":"nummod","subj":"T1098","obj":"T1102"},{"id":"R708","pred":"nummod","subj":"T1099","obj":"T1102"},{"id":"R709","pred":"compound","subj":"T1100","obj":"T1102"},{"id":"R711","pred":"compound","subj":"T1101","obj":"T1102"},{"id":"R712","pred":"pobj","subj":"T1102","obj":"T1097"},{"id":"R713","pred":"prep","subj":"T1103","obj":"T1090"},{"id":"R714","pred":"prep","subj":"T1104","obj":"T1103"},{"id":"R716","pred":"pobj","subj":"T1105","obj":"T1104"},{"id":"R717","pred":"prep","subj":"T1106","obj":"T1105"},{"id":"R718","pred":"nummod","subj":"T1107","obj":"T1111"},{"id":"R719","pred":"nummod","subj":"T1108","obj":"T1111"},{"id":"R720","pred":"compound","subj":"T1109","obj":"T1111"},{"id":"R721","pred":"compound","subj":"T1110","obj":"T1111"},{"id":"R722","pred":"pobj","subj":"T1111","obj":"T1106"},{"id":"R723","pred":"punct","subj":"T1112","obj":"T1090"},{"id":"R724","pred":"advmod","subj":"T1113","obj":"T1117"},{"id":"R725","pred":"punct","subj":"T1114","obj":"T1117"},{"id":"R726","pred":"det","subj":"T1115","obj":"T1116"},{"id":"R727","pred":"nsubj","subj":"T1116","obj":"T1117"},{"id":"R728","pred":"ROOT","subj":"T1117","obj":"T1117"},{"id":"R729","pred":"mark","subj":"T1118","obj":"T1121"},{"id":"R730","pred":"amod","subj":"T1119","obj":"T1120"},{"id":"R731","pred":"nsubj","subj":"T1120","obj":"T1121"},{"id":"R732","pred":"ccomp","subj":"T1121","obj":"T1117"},{"id":"R733","pred":"amod","subj":"T1122","obj":"T1124"},{"id":"R734","pred":"compound","subj":"T1123","obj":"T1124"},{"id":"R735","pred":"dobj","subj":"T1124","obj":"T1121"},{"id":"R736","pred":"prep","subj":"T1125","obj":"T1124"},{"id":"R737","pred":"pobj","subj":"T1126","obj":"T1125"},{"id":"R738","pred":"prep","subj":"T1127","obj":"T1121"},{"id":"R739","pred":"pobj","subj":"T1128","obj":"T1127"},{"id":"R740","pred":"prep","subj":"T1129","obj":"T1128"}],"text":"nfiltration of CD8+ cytotoxic T cell and CD57+ natural killer cells was significantly increased in melanoma tumor and spleen tissue of CCR5−/− mice compared to that of CCR5+/+ mice. Therefore, these results showed that CCR5 deficiency caused apoptotic cell death of melanoma through inhibition of NF-κB a"}

{"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T693","span":{"begin":283,"end":293},"obj":"Negative_regulation"},{"id":"T691","span":{"begin":283,"end":293},"obj":"Negative_regulation"},{"id":"T690","span":{"begin":224,"end":234},"obj":"Negative_regulation"},{"id":"T688","span":{"begin":297,"end":302},"obj":"Protein"},{"id":"T687","span":{"begin":219,"end":223},"obj":"Protein"},{"id":"T686","span":{"begin":168,"end":172},"obj":"Protein"},{"id":"T685","span":{"begin":41,"end":46},"obj":"Protein"},{"id":"T684","span":{"begin":15,"end":18},"obj":"Protein"}],"relations":[{"id":"R371","pred":"themeOf","subj":"T687","obj":"T690"},{"id":"R372","pred":"themeOf","subj":"T688","obj":"T691"},{"id":"R374","pred":"causeOf","subj":"T690","obj":"T691"},{"id":"R375","pred":"causeOf","subj":"T690","obj":"T693"}],"text":"nfiltration of CD8+ cytotoxic T cell and CD57+ natural killer cells was significantly increased in melanoma tumor and spleen tissue of CCR5−/− mice compared to that of CCR5+/+ mice. Therefore, these results showed that CCR5 deficiency caused apoptotic cell death of melanoma through inhibition of NF-κB a"}