PMC:3320587 / 9558-10352 JSONTXT

Annnotations TAB JSON ListView MergeView

    pmc-enju-pas

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infectious molecular clones\nThe plasmid encoding the full-length infectious molecular clone of HIV-1Lai was obtained from the NIH AIDS Reagent and Reference Program. The HIV-1Lai/Bal-Env infectious molecular clone was constructed by replacing the envelope (env) gp160 amino acids 103–717 of the HIV-1Lai (B subtype that utilizes CXCR4) molecular clone with the corresponding region of HIV-1Bal (B subtype that utilizes CCR5). The HIV-1Lai/Bal-Env chimeric virus uses CCR5 as a secondary receptor. The infectious molecular clone of HIV-198IN22 was constructed using DNA extracted from PBMC that were infected with a primary isolate of HIV-198IN22. HIV-1Lai/Bal-Env and HIV-198IN22 mutant viruses were constructed by introducing point mutations using standard PCR-based mutagenesis methods."}

    bionlp-st-ge-2016-test-proteins

    {"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T4329","span":{"begin":425,"end":429},"obj":"Protein"},{"id":"T4328","span":{"begin":335,"end":340},"obj":"Protein"},{"id":"T4327","span":{"begin":268,"end":273},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"HIV-1 infectious molecular clones\nThe plasmid encoding the full-length infectious molecular clone of HIV-1Lai was obtained from the NIH AIDS Reagent and Reference Program. The HIV-1Lai/Bal-Env infectious molecular clone was constructed by replacing the envelope (env) gp160 amino acids 103–717 of the HIV-1Lai (B subtype that utilizes CXCR4) molecular clone with the corresponding region of HIV-1Bal (B subtype that utilizes CCR5). The HIV-1Lai/Bal-Env chimeric virus uses CCR5 as a secondary receptor. The infectious molecular clone of HIV-198IN22 was constructed using DNA extracted from PBMC that were infected with a primary isolate of HIV-198IN22. HIV-1Lai/Bal-Env and HIV-198IN22 mutant viruses were constructed by introducing point mutations using standard PCR-based mutagenesis methods."}

    bionlp-st-ge-2016-uniprot

    {"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T4453","span":{"begin":473,"end":477},"obj":"http://www.uniprot.org/uniprot/P51681"},{"id":"T4452","span":{"begin":425,"end":429},"obj":"http://www.uniprot.org/uniprot/P51681"},{"id":"T4451","span":{"begin":263,"end":266},"obj":"http://www.uniprot.org/uniprot/P04578"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"HIV-1 infectious molecular clones\nThe plasmid encoding the full-length infectious molecular clone of HIV-1Lai was obtained from the NIH AIDS Reagent and Reference Program. The HIV-1Lai/Bal-Env infectious molecular clone was constructed by replacing the envelope (env) gp160 amino acids 103–717 of the HIV-1Lai (B subtype that utilizes CXCR4) molecular clone with the corresponding region of HIV-1Bal (B subtype that utilizes CCR5). The HIV-1Lai/Bal-Env chimeric virus uses CCR5 as a secondary receptor. The infectious molecular clone of HIV-198IN22 was constructed using DNA extracted from PBMC that were infected with a primary isolate of HIV-198IN22. HIV-1Lai/Bal-Env and HIV-198IN22 mutant viruses were constructed by introducing point mutations using standard PCR-based mutagenesis methods."}

    GO-BP

    {"project":"GO-BP","denotations":[{"id":"T4330","span":{"begin":335,"end":340},"obj":"http://purl.obolibrary.org/obo/GO_0038147"}],"text":"HIV-1 infectious molecular clones\nThe plasmid encoding the full-length infectious molecular clone of HIV-1Lai was obtained from the NIH AIDS Reagent and Reference Program. The HIV-1Lai/Bal-Env infectious molecular clone was constructed by replacing the envelope (env) gp160 amino acids 103–717 of the HIV-1Lai (B subtype that utilizes CXCR4) molecular clone with the corresponding region of HIV-1Bal (B subtype that utilizes CCR5). The HIV-1Lai/Bal-Env chimeric virus uses CCR5 as a secondary receptor. The infectious molecular clone of HIV-198IN22 was constructed using DNA extracted from PBMC that were infected with a primary isolate of HIV-198IN22. HIV-1Lai/Bal-Env and HIV-198IN22 mutant viruses were constructed by introducing point mutations using standard PCR-based mutagenesis methods."}

    GO-MF

    {"project":"GO-MF","denotations":[{"id":"T4331","span":{"begin":335,"end":340},"obj":"http://purl.obolibrary.org/obo/GO_0038147"}],"text":"HIV-1 infectious molecular clones\nThe plasmid encoding the full-length infectious molecular clone of HIV-1Lai was obtained from the NIH AIDS Reagent and Reference Program. The HIV-1Lai/Bal-Env infectious molecular clone was constructed by replacing the envelope (env) gp160 amino acids 103–717 of the HIV-1Lai (B subtype that utilizes CXCR4) molecular clone with the corresponding region of HIV-1Bal (B subtype that utilizes CCR5). The HIV-1Lai/Bal-Env chimeric virus uses CCR5 as a secondary receptor. The infectious molecular clone of HIV-198IN22 was constructed using DNA extracted from PBMC that were infected with a primary isolate of HIV-198IN22. HIV-1Lai/Bal-Env and HIV-198IN22 mutant viruses were constructed by introducing point mutations using standard PCR-based mutagenesis methods."}

    GO-CC

    {"project":"GO-CC","denotations":[{"id":"T4332","span":{"begin":253,"end":261},"obj":"http://purl.obolibrary.org/obo/GO_0009274"}],"text":"HIV-1 infectious molecular clones\nThe plasmid encoding the full-length infectious molecular clone of HIV-1Lai was obtained from the NIH AIDS Reagent and Reference Program. The HIV-1Lai/Bal-Env infectious molecular clone was constructed by replacing the envelope (env) gp160 amino acids 103–717 of the HIV-1Lai (B subtype that utilizes CXCR4) molecular clone with the corresponding region of HIV-1Bal (B subtype that utilizes CCR5). The HIV-1Lai/Bal-Env chimeric virus uses CCR5 as a secondary receptor. The infectious molecular clone of HIV-198IN22 was constructed using DNA extracted from PBMC that were infected with a primary isolate of HIV-198IN22. HIV-1Lai/Bal-Env and HIV-198IN22 mutant viruses were constructed by introducing point mutations using standard PCR-based mutagenesis methods."}

    sentences

    {"project":"sentences","denotations":[{"id":"T4323","span":{"begin":653,"end":794},"obj":"Sentence"},{"id":"T4322","span":{"begin":503,"end":652},"obj":"Sentence"},{"id":"T4321","span":{"begin":432,"end":502},"obj":"Sentence"},{"id":"T4320","span":{"begin":34,"end":431},"obj":"Sentence"},{"id":"T4319","span":{"begin":0,"end":33},"obj":"Sentence"},{"id":"T58","span":{"begin":0,"end":33},"obj":"Sentence"},{"id":"T59","span":{"begin":34,"end":171},"obj":"Sentence"},{"id":"T60","span":{"begin":172,"end":431},"obj":"Sentence"},{"id":"T61","span":{"begin":432,"end":502},"obj":"Sentence"},{"id":"T62","span":{"begin":503,"end":652},"obj":"Sentence"},{"id":"T63","span":{"begin":653,"end":794},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"HIV-1 infectious molecular clones\nThe plasmid encoding the full-length infectious molecular clone of HIV-1Lai was obtained from the NIH AIDS Reagent and Reference Program. The HIV-1Lai/Bal-Env infectious molecular clone was constructed by replacing the envelope (env) gp160 amino acids 103–717 of the HIV-1Lai (B subtype that utilizes CXCR4) molecular clone with the corresponding region of HIV-1Bal (B subtype that utilizes CCR5). The HIV-1Lai/Bal-Env chimeric virus uses CCR5 as a secondary receptor. The infectious molecular clone of HIV-198IN22 was constructed using DNA extracted from PBMC that were infected with a primary isolate of HIV-198IN22. HIV-1Lai/Bal-Env and HIV-198IN22 mutant viruses were constructed by introducing point mutations using standard PCR-based mutagenesis methods."}

    simple1

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    BioNLP16_DUT

    {"project":"BioNLP16_DUT","denotations":[{"id":"T4614","span":{"begin":425,"end":429},"obj":"Protein"},{"id":"T4613","span":{"begin":335,"end":340},"obj":"Protein"},{"id":"T4612","span":{"begin":268,"end":273},"obj":"Protein"}],"text":"HIV-1 infectious molecular clones\nThe plasmid encoding the full-length infectious molecular clone of HIV-1Lai was obtained from the NIH AIDS Reagent and Reference Program. The HIV-1Lai/Bal-Env infectious molecular clone was constructed by replacing the envelope (env) gp160 amino acids 103–717 of the HIV-1Lai (B subtype that utilizes CXCR4) molecular clone with the corresponding region of HIV-1Bal (B subtype that utilizes CCR5). The HIV-1Lai/Bal-Env chimeric virus uses CCR5 as a secondary receptor. The infectious molecular clone of HIV-198IN22 was constructed using DNA extracted from PBMC that were infected with a primary isolate of HIV-198IN22. HIV-1Lai/Bal-Env and HIV-198IN22 mutant viruses were constructed by introducing point mutations using standard PCR-based mutagenesis methods."}

    BioNLP16_Messiy

    {"project":"BioNLP16_Messiy","denotations":[{"id":"T4463","span":{"begin":425,"end":429},"obj":"Protein"},{"id":"T4462","span":{"begin":335,"end":340},"obj":"Protein"},{"id":"T4461","span":{"begin":268,"end":273},"obj":"Protein"}],"text":"HIV-1 infectious molecular clones\nThe plasmid encoding the full-length infectious molecular clone of HIV-1Lai was obtained from the NIH AIDS Reagent and Reference Program. The HIV-1Lai/Bal-Env infectious molecular clone was constructed by replacing the envelope (env) gp160 amino acids 103–717 of the HIV-1Lai (B subtype that utilizes CXCR4) molecular clone with the corresponding region of HIV-1Bal (B subtype that utilizes CCR5). The HIV-1Lai/Bal-Env chimeric virus uses CCR5 as a secondary receptor. The infectious molecular clone of HIV-198IN22 was constructed using DNA extracted from PBMC that were infected with a primary isolate of HIV-198IN22. HIV-1Lai/Bal-Env and HIV-198IN22 mutant viruses were constructed by introducing point mutations using standard PCR-based mutagenesis methods."}

    DLUT931

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    bionlp-st-ge-2016-test-ihmc

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    bionlp-st-ge-2016-spacy-parsed

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The HIV-1Lai/Bal-Env infectious molecular clone was constructed by replacing the envelope (env) gp160 amino acids 103–717 of the HIV-1Lai (B subtype that utilizes CXCR4) molecular clone with the corresponding region of HIV-1Bal (B subtype that utilizes CCR5). The HIV-1Lai/Bal-Env chimeric virus uses CCR5 as a secondary receptor. The infectious molecular clone of HIV-198IN22 was constructed using DNA extracted from PBMC that were infected with a primary isolate of HIV-198IN22. HIV-1Lai/Bal-Env and HIV-198IN22 mutant viruses were constructed by introducing point mutations using standard PCR-based mutagenesis methods."}

    bionlp-st-ge-2016-test-tees

    {"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T4475","span":{"begin":666,"end":669},"obj":"Protein"},{"id":"T4474","span":{"begin":473,"end":477},"obj":"Protein"},{"id":"T4473","span":{"begin":449,"end":452},"obj":"Protein"},{"id":"T4472","span":{"begin":326,"end":334},"obj":"Positive_regulation"},{"id":"T4471","span":{"begin":425,"end":429},"obj":"Protein"},{"id":"T4470","span":{"begin":335,"end":340},"obj":"Protein"},{"id":"T4469","span":{"begin":268,"end":273},"obj":"Protein"},{"id":"T4468","span":{"begin":263,"end":266},"obj":"Protein"},{"id":"T4467","span":{"begin":253,"end":261},"obj":"Protein"}],"relations":[{"id":"R3509","pred":"themeOf","subj":"T4470","obj":"T4472"}],"text":"HIV-1 infectious molecular clones\nThe plasmid encoding the full-length infectious molecular clone of HIV-1Lai was obtained from the NIH AIDS Reagent and Reference Program. The HIV-1Lai/Bal-Env infectious molecular clone was constructed by replacing the envelope (env) gp160 amino acids 103–717 of the HIV-1Lai (B subtype that utilizes CXCR4) molecular clone with the corresponding region of HIV-1Bal (B subtype that utilizes CCR5). The HIV-1Lai/Bal-Env chimeric virus uses CCR5 as a secondary receptor. The infectious molecular clone of HIV-198IN22 was constructed using DNA extracted from PBMC that were infected with a primary isolate of HIV-198IN22. HIV-1Lai/Bal-Env and HIV-198IN22 mutant viruses were constructed by introducing point mutations using standard PCR-based mutagenesis methods."}

    testone

    {"project":"testone","denotations":[{"id":"T4312","span":{"begin":425,"end":429},"obj":"Protein"},{"id":"T4311","span":{"begin":335,"end":340},"obj":"Protein"},{"id":"T4310","span":{"begin":268,"end":273},"obj":"Protein"}],"text":"HIV-1 infectious molecular clones\nThe plasmid encoding the full-length infectious molecular clone of HIV-1Lai was obtained from the NIH AIDS Reagent and Reference Program. The HIV-1Lai/Bal-Env infectious molecular clone was constructed by replacing the envelope (env) gp160 amino acids 103–717 of the HIV-1Lai (B subtype that utilizes CXCR4) molecular clone with the corresponding region of HIV-1Bal (B subtype that utilizes CCR5). The HIV-1Lai/Bal-Env chimeric virus uses CCR5 as a secondary receptor. The infectious molecular clone of HIV-198IN22 was constructed using DNA extracted from PBMC that were infected with a primary isolate of HIV-198IN22. HIV-1Lai/Bal-Env and HIV-198IN22 mutant viruses were constructed by introducing point mutations using standard PCR-based mutagenesis methods."}

    test3

    {"project":"test3","denotations":[{"id":"T4318","span":{"begin":425,"end":429},"obj":"Protein"},{"id":"T4317","span":{"begin":335,"end":340},"obj":"Protein"},{"id":"T4316","span":{"begin":268,"end":273},"obj":"Protein"},{"id":"T4315","span":{"begin":425,"end":429},"obj":"Protein"},{"id":"T4314","span":{"begin":335,"end":340},"obj":"Protein"},{"id":"T4313","span":{"begin":268,"end":273},"obj":"Protein"}],"text":"HIV-1 infectious molecular clones\nThe plasmid encoding the full-length infectious molecular clone of HIV-1Lai was obtained from the NIH AIDS Reagent and Reference Program. The HIV-1Lai/Bal-Env infectious molecular clone was constructed by replacing the envelope (env) gp160 amino acids 103–717 of the HIV-1Lai (B subtype that utilizes CXCR4) molecular clone with the corresponding region of HIV-1Bal (B subtype that utilizes CCR5). The HIV-1Lai/Bal-Env chimeric virus uses CCR5 as a secondary receptor. The infectious molecular clone of HIV-198IN22 was constructed using DNA extracted from PBMC that were infected with a primary isolate of HIV-198IN22. HIV-1Lai/Bal-Env and HIV-198IN22 mutant viruses were constructed by introducing point mutations using standard PCR-based mutagenesis methods."}