PMC:3312845 / 926-1530 JSONTXT

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    pmc-enju-pas

    {"project":"pmc-enju-pas","denotations":[{"id":"T422","span":{"begin":601,"end":603},"obj":"NN"},{"id":"T421","span":{"begin":597,"end":600},"obj":"DT"},{"id":"T420","span":{"begin":594,"end":596},"obj":"IN"},{"id":"T419","span":{"begin":581,"end":593},"obj":"NN"},{"id":"T418","span":{"begin":570,"end":580},"obj":"NN"},{"id":"T417","span":{"begin":559,"end":569},"obj":"JJ"},{"id":"T416","span":{"begin":551,"end":558},"obj":"VB"},{"id":"T415","span":{"begin":542,"end":550},"obj":"NN"},{"id":"T414","span":{"begin":533,"end":541},"obj":"NN"},{"id":"T413","span":{"begin":531,"end":532},"obj":"-COMMA-"},{"id":"T412","span":{"begin":520,"end":531},"obj":"RB"},{"id":"T411","span":{"begin":513,"end":518},"obj":"NN"},{"id":"T410","span":{"begin":501,"end":512},"obj":"JJ"},{"id":"T409","span":{"begin":498,"end":500},"obj":"IN"},{"id":"T408","span":{"begin":482,"end":497},"obj":"NN"},{"id":"T407","span":{"begin":471,"end":481},"obj":"NN"},{"id":"T406","span":{"begin":468,"end":470},"obj":"IN"},{"id":"T405","span":{"begin":457,"end":467},"obj":"NN"},{"id":"T404","span":{"begin":453,"end":456},"obj":"IN"},{"id":"T403","span":{"begin":445,"end":452},"obj":"NN"},{"id":"T402","span":{"begin":436,"end":444},"obj":"JJ"},{"id":"T401","span":{"begin":432,"end":435},"obj":"CC"},{"id":"T400","span":{"begin":426,"end":431},"obj":"NN"},{"id":"T399","span":{"begin":416,"end":425},"obj":"JJ"},{"id":"T398","span":{"begin":405,"end":415},"obj":"JJ"},{"id":"T397","span":{"begin":394,"end":404},"obj":"VB"},{"id":"T396","span":{"begin":385,"end":393},"obj":"NN"},{"id":"T395","span":{"begin":383,"end":384},"obj":"-RRB-"},{"id":"T394","span":{"begin":375,"end":383},"obj":"NN"},{"id":"T393","span":{"begin":374,"end":375},"obj":"-LRB-"},{"id":"T392","span":{"begin":365,"end":373},"obj":"NN"},{"id":"T391","span":{"begin":361,"end":364},"obj":"NN"},{"id":"T390","span":{"begin":357,"end":360},"obj":"NN"},{"id":"T389","span":{"begin":349,"end":356},"obj":"JJ"},{"id":"T388","span":{"begin":346,"end":348},"obj":"IN"},{"id":"T387","span":{"begin":340,"end":345},"obj":"NN"},{"id":"T386","span":{"begin":337,"end":339},"obj":"IN"},{"id":"T385","span":{"begin":322,"end":336},"obj":"NN"},{"id":"T384","span":{"begin":319,"end":320},"obj":"-RRB-"},{"id":"T383","span":{"begin":312,"end":319},"obj":"NN"},{"id":"T382","span":{"begin":304,"end":311},"obj":"NN"},{"id":"T381","span":{"begin":292,"end":303},"obj":"JJ"},{"id":"T380","span":{"begin":289,"end":291},"obj":"DT"},{"id":"T379","span":{"begin":288,"end":289},"obj":"-LRB-"},{"id":"T378","span":{"begin":277,"end":287},"obj":"NN"},{"id":"T377","span":{"begin":270,"end":276},"obj":"NN"},{"id":"T376","span":{"begin":267,"end":269},"obj":"IN"},{"id":"T375","span":{"begin":255,"end":266},"obj":"VB"},{"id":"T374","span":{"begin":249,"end":254},"obj":"NN"},{"id":"T373","span":{"begin":237,"end":248},"obj":"JJ"},{"id":"T372","span":{"begin":234,"end":236},"obj":"IN"},{"id":"T371","span":{"begin":224,"end":233},"obj":"VB"},{"id":"T370","span":{"begin":220,"end":223},"obj":"VB"},{"id":"T369","span":{"begin":204,"end":219},"obj":"NN"},{"id":"T368","span":{"begin":193,"end":203},"obj":"NN"},{"id":"T367","span":{"begin":188,"end":192},"obj":"RB"},{"id":"T366","span":{"begin":186,"end":187},"obj":"-COMMA-"},{"id":"T365","span":{"begin":178,"end":186},"obj":"NN"},{"id":"T364","span":{"begin":175,"end":177},"obj":"IN"},{"id":"T363","span":{"begin":163,"end":173},"obj":"NN"},{"id":"T362","span":{"begin":160,"end":162},"obj":"IN"},{"id":"T361","span":{"begin":155,"end":159},"obj":"RB"},{"id":"T360","span":{"begin":152,"end":154},"obj":"RB"},{"id":"T359","span":{"begin":146,"end":151},"obj":"NN"},{"id":"T358","span":{"begin":134,"end":145},"obj":"JJ"},{"id":"T357","span":{"begin":131,"end":133},"obj":"IN"},{"id":"T356","span":{"begin":122,"end":130},"obj":"VB"},{"id":"T355","span":{"begin":118,"end":121},"obj":"VB"},{"id":"T354","span":{"begin":107,"end":117},"obj":"NN"},{"id":"T353","span":{"begin":98,"end":106},"obj":"NN"},{"id":"T352","span":{"begin":94,"end":97},"obj":"NN"},{"id":"T351","span":{"begin":90,"end":93},"obj":"NN"},{"id":"T350","span":{"begin":88,"end":89},"obj":"-COMMA-"},{"id":"T349","span":{"begin":80,"end":88},"obj":"NN"},{"id":"T348","span":{"begin":77,"end":79},"obj":"IN"},{"id":"T347","span":{"begin":59,"end":75},"obj":"NN"},{"id":"T346","span":{"begin":53,"end":58},"obj":"NN"},{"id":"T345","span":{"begin":46,"end":52},"obj":"JJ"},{"id":"T344","span":{"begin":39,"end":45},"obj":"VB"},{"id":"T343","span":{"begin":29,"end":38},"obj":"NN"},{"id":"T342","span":{"begin":19,"end":28},"obj":"VB"},{"id":"T341","span":{"begin":14,"end":18},"obj":"RB"},{"id":"T340","span":{"begin":12,"end":13},"obj":"-COMMA-"},{"id":"T339","span":{"begin":10,"end":12},"obj":"NN"},{"id":"T338","span":{"begin":0,"end":9},"obj":"VB"}],"relations":[{"id":"R169","pred":"arg2Of","subj":"T339","obj":"T338"},{"id":"R170","pred":"arg1Of","subj":"T343","obj":"T341"},{"id":"R171","pred":"arg2Of","subj":"T343","obj":"T342"},{"id":"R172","p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SE, most activated microglia showed strong TNF-α immunoreactivity. In addition, TNF p75 receptor expression was detected in endothelial cells as well as astrocytes. In addition, only p65-Thr435 phosphorylation was increased in endothelial cells accompanied by SMI-71 expression (an endothelial barrier antigen). Neutralization of TNF-α by soluble TNF p55 receptor (sTNFp55R) infusion attenuated SE-induced vasogenic edema and neuronal damages via inhibition of p65-Thr435 phosphorylation in endothelial cells. Furthermore, sTNFp55R infusion reduced SE-induced neutrophil infiltration in the PC."}

    bionlp-st-ge-2016-test-proteins

    {"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T151","span":{"begin":53,"end":58},"obj":"Protein"},{"id":"T152","span":{"begin":90,"end":106},"obj":"Protein"},{"id":"T153","span":{"begin":193,"end":196},"obj":"Protein"},{"id":"T154","span":{"begin":340,"end":345},"obj":"Protein"},{"id":"T155","span":{"begin":357,"end":373},"obj":"Protein"},{"id":"T156","span":{"begin":376,"end":383},"obj":"Protein"},{"id":"T157","span":{"begin":471,"end":474},"obj":"Protein"},{"id":"T158","span":{"begin":534,"end":541},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Following SE, most activated microglia showed strong TNF-α immunoreactivity. In addition, TNF p75 receptor expression was detected in endothelial cells as well as astrocytes. In addition, only p65-Thr435 phosphorylation was increased in endothelial cells accompanied by SMI-71 expression (an endothelial barrier antigen). Neutralization of TNF-α by soluble TNF p55 receptor (sTNFp55R) infusion attenuated SE-induced vasogenic edema and neuronal damages via inhibition of p65-Thr435 phosphorylation in endothelial cells. Furthermore, sTNFp55R infusion reduced SE-induced neutrophil infiltration in the PC."}

    bionlp-st-ge-2016-uniprot

    {"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T479","span":{"begin":361,"end":364},"obj":"http://www.uniprot.org/uniprot/P01589"},{"id":"T476","span":{"begin":340,"end":345},"obj":"http://www.uniprot.org/uniprot/P01375"},{"id":"T459","span":{"begin":193,"end":196},"obj":"http://www.uniprot.org/uniprot/Q04206"},{"id":"T460","span":{"begin":471,"end":474},"obj":"http://www.uniprot.org/uniprot/Q04206"},{"id":"T463","span":{"begin":193,"end":196},"obj":"http://www.uniprot.org/uniprot/P21579"},{"id":"T464","span":{"begin":471,"end":474},"obj":"http://www.uniprot.org/uniprot/P21579"},{"id":"T469","span":{"begin":53,"end":56},"obj":"http://www.uniprot.org/uniprot/P01375"},{"id":"T470","span":{"begin":90,"end":93},"obj":"http://www.uniprot.org/uniprot/P01375"},{"id":"T471","span":{"begin":340,"end":343},"obj":"http://www.uniprot.org/uniprot/P01375"},{"id":"T472","span":{"begin":357,"end":360},"obj":"http://www.uniprot.org/uniprot/P01375"},{"id":"T475","span":{"begin":53,"end":58},"obj":"http://www.uniprot.org/uniprot/P01375"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"Following SE, most activated microglia showed strong TNF-α immunoreactivity. In addition, TNF p75 receptor expression was detected in endothelial cells as well as astrocytes. In addition, only p65-Thr435 phosphorylation was increased in endothelial cells accompanied by SMI-71 expression (an endothelial barrier antigen). Neutralization of TNF-α by soluble TNF p55 receptor (sTNFp55R) infusion attenuated SE-induced vasogenic edema and neuronal damages via inhibition of p65-Thr435 phosphorylation in endothelial cells. Furthermore, sTNFp55R infusion reduced SE-induced neutrophil infiltration in the PC."}

    GO-BP

    {"project":"GO-BP","denotations":[{"id":"T171","span":{"begin":482,"end":497},"obj":"http://purl.obolibrary.org/obo/GO_0016310"},{"id":"T170","span":{"begin":204,"end":219},"obj":"http://purl.obolibrary.org/obo/GO_0016310"}],"text":"Following SE, most activated microglia showed strong TNF-α immunoreactivity. In addition, TNF p75 receptor expression was detected in endothelial cells as well as astrocytes. In addition, only p65-Thr435 phosphorylation was increased in endothelial cells accompanied by SMI-71 expression (an endothelial barrier antigen). Neutralization of TNF-α by soluble TNF p55 receptor (sTNFp55R) infusion attenuated SE-induced vasogenic edema and neuronal damages via inhibition of p65-Thr435 phosphorylation in endothelial cells. Furthermore, sTNFp55R infusion reduced SE-induced neutrophil infiltration in the PC."}

    GO-CC

    {"project":"GO-CC","denotations":[{"id":"T181","span":{"begin":146,"end":151},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T182","span":{"begin":249,"end":254},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T183","span":{"begin":513,"end":518},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"Following SE, most activated microglia showed strong TNF-α immunoreactivity. In addition, TNF p75 receptor expression was detected in endothelial cells as well as astrocytes. In addition, only p65-Thr435 phosphorylation was increased in endothelial cells accompanied by SMI-71 expression (an endothelial barrier antigen). Neutralization of TNF-α by soluble TNF p55 receptor (sTNFp55R) infusion attenuated SE-induced vasogenic edema and neuronal damages via inhibition of p65-Thr435 phosphorylation in endothelial cells. Furthermore, sTNFp55R infusion reduced SE-induced neutrophil infiltration in the PC."}

    sentences

    {"project":"sentences","denotations":[{"id":"T114","span":{"begin":520,"end":604},"obj":"Sentence"},{"id":"T113","span":{"begin":322,"end":519},"obj":"Sentence"},{"id":"T112","span":{"begin":175,"end":321},"obj":"Sentence"},{"id":"T111","span":{"begin":77,"end":174},"obj":"Sentence"},{"id":"T110","span":{"begin":0,"end":76},"obj":"Sentence"},{"id":"T10","span":{"begin":0,"end":76},"obj":"Sentence"},{"id":"T11","span":{"begin":77,"end":174},"obj":"Sentence"},{"id":"T12","span":{"begin":175,"end":321},"obj":"Sentence"},{"id":"T13","span":{"begin":322,"end":519},"obj":"Sentence"},{"id":"T14","span":{"begin":520,"end":604},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Following SE, most activated microglia showed strong TNF-α immunoreactivity. In addition, TNF p75 receptor expression was detected in endothelial cells as well as astrocytes. In addition, only p65-Thr435 phosphorylation was increased in endothelial cells accompanied by SMI-71 expression (an endothelial barrier antigen). Neutralization of TNF-α by soluble TNF p55 receptor (sTNFp55R) infusion attenuated SE-induced vasogenic edema and neuronal damages via inhibition of p65-Thr435 phosphorylation in endothelial cells. Furthermore, sTNFp55R infusion reduced SE-induced neutrophil infiltration in the PC."}

    simple1

    {"project":"simple1","denotations":[{"id":"T198","span":{"begin":534,"end":541},"obj":"Protein"},{"id":"T197","span":{"begin":471,"end":474},"obj":"Protein"},{"id":"T196","span":{"begin":376,"end":383},"obj":"Protein"},{"id":"T195","span":{"begin":357,"end":373},"obj":"Protein"},{"id":"T194","span":{"begin":340,"end":345},"obj":"Protein"},{"id":"T193","span":{"begin":193,"end":196},"obj":"Protein"},{"id":"T192","span":{"begin":90,"end":106},"obj":"Protein"},{"id":"T191","span":{"begin":53,"end":58},"obj":"Protein"}],"text":"Following SE, most activated microglia showed strong TNF-α immunoreactivity. In addition, TNF p75 receptor expression was detected in endothelial cells as well as astrocytes. In addition, only p65-Thr435 phosphorylation was increased in endothelial cells accompanied by SMI-71 expression (an endothelial barrier antigen). Neutralization of TNF-α by soluble TNF p55 receptor (sTNFp55R) infusion attenuated SE-induced vasogenic edema and neuronal damages via inhibition of p65-Thr435 phosphorylation in endothelial cells. Furthermore, sTNFp55R infusion reduced SE-induced neutrophil infiltration in the PC."}

    BioNLP16_DUT

    {"project":"BioNLP16_DUT","denotations":[{"id":"T915","span":{"begin":53,"end":58},"obj":"Protein"},{"id":"T916","span":{"begin":90,"end":106},"obj":"Protein"},{"id":"T917","span":{"begin":193,"end":196},"obj":"Protein"},{"id":"T918","span":{"begin":340,"end":345},"obj":"Protein"},{"id":"T919","span":{"begin":357,"end":373},"obj":"Protein"},{"id":"T920","span":{"begin":376,"end":383},"obj":"Protein"},{"id":"T921","span":{"begin":471,"end":474},"obj":"Protein"},{"id":"T922","span":{"begin":534,"end":541},"obj":"Protein"},{"id":"T926","span":{"begin":107,"end":117},"obj":"Gene_expression"},{"id":"T927","span":{"begin":224,"end":233},"obj":"Positive_regulation"},{"id":"T928","span":{"begin":204,"end":219},"obj":"Phosphorylation"},{"id":"T929","span":{"begin":482,"end":497},"obj":"Phosphorylation"},{"id":"T930","span":{"begin":457,"end":467},"obj":"Negative_regulation"},{"id":"T931","span":{"begin":322,"end":336},"obj":"Negative_regulation"}],"relations":[{"id":"R647","pred":"themeOf","subj":"T916","obj":"T926"},{"id":"R648","pred":"themeOf","subj":"T917","obj":"T928"},{"id":"R649","pred":"themeOf","subj":"T918","obj":"T931"},{"id":"R650","pred":"themeOf","subj":"T921","obj":"T929"},{"id":"R651","pred":"themeOf","subj":"T928","obj":"T927"},{"id":"R652","pred":"themeOf","subj":"T929","obj":"T930"}],"text":"Following SE, most activated microglia showed strong TNF-α immunoreactivity. In addition, TNF p75 receptor expression was detected in endothelial cells as well as astrocytes. In addition, only p65-Thr435 phosphorylation was increased in endothelial cells accompanied by SMI-71 expression (an endothelial barrier antigen). Neutralization of TNF-α by soluble TNF p55 receptor (sTNFp55R) infusion attenuated SE-induced vasogenic edema and neuronal damages via inhibition of p65-Thr435 phosphorylation in endothelial cells. Furthermore, sTNFp55R infusion reduced SE-induced neutrophil infiltration in the PC."}

    BioNLP16_Messiy

    {"project":"BioNLP16_Messiy","denotations":[{"id":"T768","span":{"begin":107,"end":117},"obj":"Gene_expression"},{"id":"T763","span":{"begin":534,"end":541},"obj":"Protein"},{"id":"T762","span":{"begin":471,"end":474},"obj":"Protein"},{"id":"T761","span":{"begin":376,"end":383},"obj":"Protein"},{"id":"T760","span":{"begin":357,"end":373},"obj":"Protein"},{"id":"T759","span":{"begin":340,"end":345},"obj":"Protein"},{"id":"T758","span":{"begin":193,"end":196},"obj":"Protein"},{"id":"T757","span":{"begin":90,"end":106},"obj":"Protein"},{"id":"T756","span":{"begin":53,"end":58},"obj":"Protein"},{"id":"T773","span":{"begin":457,"end":467},"obj":"Negative_regulation"},{"id":"T772","span":{"begin":482,"end":497},"obj":"Phosphorylation"},{"id":"T771","span":{"begin":322,"end":336},"obj":"Negative_regulation"},{"id":"T770","span":{"begin":224,"end":233},"obj":"Positive_regulation"},{"id":"T769","span":{"begin":204,"end":219},"obj":"Phosphorylation"}],"relations":[{"id":"R556","pred":"themeOf","subj":"T757","obj":"T768"},{"id":"R557","pred":"themeOf","subj":"T758","obj":"T769"},{"id":"R558","pred":"themeOf","subj":"T759","obj":"T771"},{"id":"R559","pred":"themeOf","subj":"T762","obj":"T772"},{"id":"R564","pred":"themeOf","subj":"T769","obj":"T770"},{"id":"R565","pred":"themeOf","subj":"T772","obj":"T773"}],"text":"Following SE, most activated microglia showed strong TNF-α immunoreactivity. In addition, TNF p75 receptor expression was detected in endothelial cells as well as astrocytes. In addition, only p65-Thr435 phosphorylation was increased in endothelial cells accompanied by SMI-71 expression (an endothelial barrier antigen). Neutralization of TNF-α by soluble TNF p55 receptor (sTNFp55R) infusion attenuated SE-induced vasogenic edema and neuronal damages via inhibition of p65-Thr435 phosphorylation in endothelial cells. Furthermore, sTNFp55R infusion reduced SE-induced neutrophil infiltration in the PC."}

    DLUT931

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    bionlp-st-ge-2016-test-ihmc

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