PMC:3291650 / 33398-34365
Annnotations
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T15462 | 965-966 | -RRB- | denotes | ] |
T15461 | 963-965 | CD | denotes | 85 |
T15460 | 962-963 | -LRB- | denotes | [ |
T15459 | 955-961 | NNP | denotes | Muench |
T15458 | 951-954 | CC | denotes | and |
T15457 | 946-950 | NNP | denotes | Reed |
T15456 | 943-945 | IN | denotes | of |
T15455 | 936-942 | NN | denotes | method |
T15454 | 932-935 | DT | denotes | the |
T15453 | 929-931 | TO | denotes | to |
T15452 | 919-928 | VB | denotes | according |
T15451 | 908-918 | VB | denotes | calculated |
T15450 | 903-907 | RB | denotes | then |
T15449 | 898-902 | VB | denotes | were |
T15448 | 891-897 | NN | denotes | titers |
T15447 | 884-890 | NN | denotes | TCID50 |
T15446 | 873-882 | VB | denotes | monitored |
T15445 | 869-872 | VB | denotes | was |
T15444 | 852-868 | NN | denotes | hemagglutination |
T15443 | 849-851 | IN | denotes | of |
T15442 | 840-848 | NN | denotes | dilution |
T15441 | 830-839 | JJ | denotes | end-point |
T15440 | 826-829 | CC | denotes | and |
T15439 | 820-825 | VB | denotes | added |
T15438 | 815-819 | VB | denotes | were |
T15437 | 813-814 | -RRB- | denotes | ) |
T15436 | 810-813 | NN | denotes | RBC |
T15435 | 809-810 | -LRB- | denotes | ( |
T15434 | 803-808 | NN | denotes | cells |
T15433 | 797-802 | NN | denotes | blood |
T15432 | 793-796 | JJ | denotes | red |
T15431 | 785-792 | NN | denotes | chicken |
T15430 | 783-784 | NN | denotes | % |
T15429 | 780-783 | CD | denotes | 0.5 |
T15428 | 778-779 | -COMMA- | denotes | , |
T15427 | 770-778 | NN | denotes | read-out |
T15426 | 766-769 | IN | denotes | For |
T15425 | 753-764 | NN | denotes | antibiotics |
T15424 | 749-752 | CC | denotes | and |
T15423 | 740-748 | NN | denotes | pyruvate |
T15422 | 733-739 | NN | denotes | sodium |
T15421 | 730-732 | NN | denotes | mM |
T15420 | 726-729 | CD | denotes | 0.4 |
T15419 | 724-725 | -COMMA- | denotes | , |
T15418 | 713-724 | NN | denotes | L-glutamine |
T15417 | 710-712 | NN | denotes | mM |
T15416 | 708-709 | CD | denotes | 2 |
T15415 | 706-707 | -COMMA- | denotes | , |
T15414 | 705-706 | -RRB- | denotes | ) |
T15413 | 700-705 | NN | denotes | µg/ml |
T15412 | 698-699 | CD | denotes | 1 |
T15411 | 697-698 | -LRB- | denotes | ( |
T15410 | 689-696 | NN | denotes | trypsin |
T15409 | 684-688 | IN | denotes | with |
T15408 | 671-683 | VB | denotes | supplemented |
T15407 | 666-670 | NN | denotes | DMEM |
T15406 | 663-665 | IN | denotes | in |
T15405 | 658-662 | NN | denotes | days |
T15404 | 656-657 | CD | denotes | 5 |
T15403 | 652-655 | IN | denotes | for |
T15402 | 646-651 | NN | denotes | cells |
T15401 | 641-645 | NN | denotes | MDCK |
T15400 | 638-640 | IN | denotes | on |
T15399 | 628-637 | VB | denotes | incubated |
T15398 | 623-627 | VB | denotes | were |
T15397 | 611-622 | NN | denotes | homogenates |
T15396 | 606-610 | NN | denotes | lung |
T15395 | 603-605 | IN | denotes | of |
T15394 | 593-602 | NN | denotes | dilutions |
T15393 | 586-592 | JJ | denotes | serial |
T15392 | 575-585 | JJ | denotes | Eight-fold |
T15391 | 570-573 | NNP | denotes | PBS |
T15390 | 567-569 | IN | denotes | in |
T15389 | 565-566 | -RRB- | denotes | ) |
T15388 | 555-565 | NN | denotes | Kinematica |
T15387 | 554-555 | -LRB- | denotes | ( |
T15386 | 542-553 | NN | denotes | homogenizer |
T15385 | 533-541 | NN | denotes | Polytron |
T15384 | 531-532 | DT | denotes | a |
T15383 | 526-530 | IN | denotes | with |
T15382 | 514-525 | VB | denotes | homogenized |
T15381 | 509-513 | VB | denotes | were |
T15380 | 503-508 | NN | denotes | lungs |
T15379 | 501-502 | -COLON- | denotes | : |
T15378 | 494-501 | VB | denotes | follows |
T15377 | 491-493 | IN | denotes | as |
T15376 | 482-490 | VB | denotes | measured |
T15375 | 478-481 | VB | denotes | was |
T15374 | 476-477 | -RRB- | denotes | ) |
T15373 | 470-476 | NN | denotes | TCID50 |
T15372 | 469-470 | -LRB- | denotes | ( |
T15371 | 464-468 | NN | denotes | dose |
T15370 | 453-463 | JJ | denotes | infectious |
T15369 | 445-452 | NN | denotes | culture |
T15368 | 438-444 | NN | denotes | tissue |
T15367 | 431-437 | JJ | denotes | median |
T15366 | 429-430 | -COMMA- | denotes | , |
T15365 | 423-429 | NN | denotes | titers |
T15364 | 417-422 | JJ | denotes | viral |
T15363 | 407-416 | JJ | denotes | pulmonary |
T15362 | 397-406 | VB | denotes | determine |
T15361 | 394-396 | TO | denotes | To |
T15360 | 388-392 | NN | denotes | X-47 |
T15330 | 213-218 | NN | denotes | mg/kg |
T15329 | 210-212 | CD | denotes | 12 |
T15328 | 209-210 | -LRB- | denotes | ( |
T15327 | 200-208 | NN | denotes | ketamine |
T15326 | 195-199 | IN | denotes | with |
T15325 | 185-194 | NN | denotes | injection |
T15324 | 180-184 | JJ | denotes | i.p. |
T15323 | 177-179 | IN | denotes | by |
T15322 | 164-176 | VB | denotes | anesthetized |
T15321 | 159-163 | VB | denotes | were |
T15320 | 154-158 | NN | denotes | mice |
T15319 | 152-153 | -COMMA- | denotes | , |
T15318 | 141-152 | NN | denotes | inoculation |
T15317 | 135-140 | JJ | denotes | viral |
T15316 | 131-134 | IN | denotes | For |
T15315 | 124-129 | NN | denotes | cells |
T15314 | 119-123 | NN | denotes | MDCK |
T15313 | 116-118 | IN | denotes | in |
T15312 | 105-115 | VB | denotes | propagated |
T15311 | 101-104 | VB | denotes | was |
T15310 | 99-100 | -RRB- | denotes | ) |
T15309 | 80-99 | NN | denotes | PR8×A/Victoria/3/75 |
T15308 | 78-79 | -COLON- | denotes | ; |
T15307 | 74-78 | NN | denotes | H3N2 |
T15306 | 73-74 | -LRB- | denotes | ( |
T15305 | 68-72 | NN | denotes | X-47 |
T15304 | 64-67 | NN | denotes | IAV |
T15303 | 56-63 | VB | denotes | adapted |
T15302 | 50-55 | NN | denotes | Mouse |
T15301 | 43-49 | NN | denotes | titers |
T15300 | 37-42 | JJ | denotes | viral |
T15299 | 34-36 | IN | denotes | of |
T15298 | 20-33 | NN | denotes | determination |
T15297 | 16-19 | CC | denotes | and |
T15296 | 6-15 | NN | denotes | infection |
T15295 | 0-5 | JJ | denotes | Viral |
T15359 | 378-387 | CD | denotes | 0.05-LD50 |
T15358 | 375-377 | CC | denotes | or |
T15357 | 368-374 | NN | denotes | 2-LD50 |
T15356 | 355-367 | RB | denotes | respectively |
T15355 | 346-354 | VB | denotes | received |
T15354 | 341-345 | NN | denotes | mice |
T15353 | 339-340 | -COMMA- | denotes | , |
T15352 | 330-339 | NN | denotes | infection |
T15351 | 320-329 | JJ | denotes | sublethal |
T15350 | 316-319 | CC | denotes | and |
T15349 | 309-315 | JJ | denotes | lethal |
T15348 | 305-308 | IN | denotes | For |
T15347 | 291-303 | RB | denotes | intranasally |
T15346 | 278-290 | VB | denotes | administered |
T15345 | 274-277 | VB | denotes | was |
T15344 | 270-273 | NNP | denotes | PBS |
T15343 | 267-269 | IN | denotes | in |
T15342 | 259-266 | VB | denotes | diluted |
T15341 | 254-258 | NN | denotes | X-47 |
T15340 | 251-253 | NN | denotes | µl |
T15339 | 248-250 | CD | denotes | 50 |
T15338 | 244-247 | CC | denotes | and |
T15337 | 242-243 | -RRB- | denotes | ) |
T15336 | 237-242 | NN | denotes | mg/kg |
T15335 | 234-236 | CD | denotes | 60 |
T15334 | 233-234 | -LRB- | denotes | ( |
T15333 | 224-232 | NN | denotes | xylazine |
T15332 | 220-223 | CC | denotes | and |
T15331 | 218-219 | -RRB- | denotes | ) |
R11393 | T15296 | T15295 | arg1Of | infection,Viral |
R11394 | T15296 | T15297 | arg1Of | infection,and |
R11395 | T15297 | T15299 | arg1Of | and,of |
R11396 | T15298 | T15297 | arg2Of | determination,and |
R11397 | T15301 | T15299 | arg2Of | titers,of |
R11398 | T15301 | T15300 | arg1Of | titers,viral |
R11399 | T15302 | T15303 | arg1Of | Mouse,adapted |
R11400 | T15305 | T15304 | arg1Of | X-47,IAV |
R11401 | T15305 | T15306 | arg1Of | X-47,( |
R11402 | T15305 | T15311 | arg1Of | X-47,was |
R11403 | T15305 | T15312 | arg2Of | X-47,propagated |
R11404 | T15307 | T15306 | arg2Of | H3N2,( |
R11405 | T15307 | T15308 | arg1Of | H3N2,; |
R11406 | T15309 | T15308 | arg2Of | PR8×A/Victoria/3/75,; |
R11407 | T15310 | T15306 | arg3Of | ),( |
R11408 | T15312 | T15303 | arg2Of | propagated,adapted |
R11409 | T15312 | T15311 | arg2Of | propagated,was |
R11410 | T15312 | T15313 | arg1Of | propagated,in |
R11411 | T15315 | T15313 | arg2Of | cells,in |
R11412 | T15315 | T15314 | arg1Of | cells,MDCK |
R11413 | T15318 | T15316 | arg2Of | inoculation,For |
R11414 | T15318 | T15317 | arg1Of | inoculation,viral |
R11415 | T15320 | T15321 | arg1Of | mice,were |
R11416 | T15320 | T15322 | arg2Of | mice,anesthetized |
R11417 | T15322 | T15316 | arg1Of | anesthetized,For |
R11418 | T15322 | T15319 | arg1Of | anesthetized,"," |
R11419 | T15322 | T15321 | arg2Of | anesthetized,were |
R11420 | T15325 | T15322 | arg1Of | injection,anesthetized |
R11421 | T15325 | T15323 | arg2Of | injection,by |
R11422 | T15325 | T15324 | arg1Of | injection,i.p. |
R11423 | T15325 | T15326 | arg1Of | injection,with |
R11424 | T15327 | T15328 | arg1Of | ketamine,( |
R11425 | T15327 | T15332 | arg1Of | ketamine,and |
R11426 | T15330 | T15328 | arg2Of | mg/kg,( |
R11427 | T15330 | T15329 | arg1Of | mg/kg,12 |
R11428 | T15331 | T15328 | arg3Of | ),( |
R11429 | T15332 | T15338 | arg1Of | and,and |
R11430 | T15333 | T15332 | arg2Of | xylazine,and |
R11431 | T15333 | T15334 | arg1Of | xylazine,( |
R11432 | T15336 | T15334 | arg2Of | mg/kg,( |
R11433 | T15336 | T15335 | arg1Of | mg/kg,60 |
R11434 | T15337 | T15334 | arg3Of | ),( |
R11435 | T15338 | T15326 | arg2Of | and,with |
R11436 | T15341 | T15338 | arg2Of | X-47,and |
R11437 | T15341 | T15339 | arg1Of | X-47,50 |
R11438 | T15341 | T15340 | arg1Of | X-47,µl |
R11439 | T15341 | T15342 | arg2Of | X-47,diluted |
R11440 | T15342 | T15343 | arg1Of | diluted,in |
R11441 | T15344 | T15345 | arg1Of | PBS,was |
R11442 | T15344 | T15346 | arg2Of | PBS,administered |
R11443 | T15346 | T15343 | arg2Of | administered,in |
R11444 | T15346 | T15345 | arg2Of | administered,was |
R11445 | T15346 | T15347 | arg1Of | administered,intranasally |
R11446 | T15349 | T15350 | arg1Of | lethal,and |
R11447 | T15351 | T15350 | arg2Of | sublethal,and |
R11448 | T15352 | T15348 | arg2Of | infection,For |
R11449 | T15352 | T15349 | arg1Of | infection,lethal |
R11450 | T15352 | T15351 | arg1Of | infection,sublethal |
R11451 | T15354 | T15355 | arg1Of | mice,received |
R11452 | T15355 | T15348 | arg1Of | received,For |
R11453 | T15355 | T15353 | arg1Of | received,"," |
R11454 | T15355 | T15356 | arg1Of | received,respectively |
R11455 | T15357 | T15358 | arg1Of | 2-LD50,or |
R11456 | T15358 | T15355 | arg2Of | or,received |
R11457 | T15360 | T15358 | arg2Of | X-47,or |
R11458 | T15360 | T15359 | arg1Of | X-47,0.05-LD50 |
R11459 | T15362 | T15361 | arg1Of | determine,To |
R11460 | T15365 | T15362 | arg2Of | titers,determine |
R11461 | T15365 | T15363 | arg1Of | titers,pulmonary |
R11462 | T15365 | T15364 | arg1Of | titers,viral |
R11463 | T15371 | T15362 | arg1Of | dose,determine |
R11464 | T15371 | T15367 | arg1Of | dose,median |
R11465 | T15371 | T15368 | arg1Of | dose,tissue |
R11466 | T15371 | T15369 | arg1Of | dose,culture |
R11467 | T15371 | T15370 | arg1Of | dose,infectious |
R11468 | T15371 | T15372 | arg1Of | dose,( |
R11469 | T15371 | T15375 | arg1Of | dose,was |
R11470 | T15371 | T15376 | arg2Of | dose,measured |
R11471 | T15371 | T15378 | arg1Of | dose,follows |
R11472 | T15373 | T15372 | arg2Of | TCID50,( |
R11473 | T15374 | T15372 | arg3Of | ),( |
R11474 | T15376 | T15375 | arg2Of | measured,was |
R11475 | T15376 | T15377 | arg1Of | measured,as |
R11476 | T15377 | T15361 | modOf | as,To |
R11477 | T15377 | T15366 | arg1Of | as,"," |
R11478 | T15378 | T15377 | arg2Of | follows,as |
R11479 | T15378 | T15379 | arg1Of | follows,: |
R11480 | T15380 | T15381 | arg1Of | lungs,were |
R11481 | T15380 | T15382 | arg2Of | lungs,homogenized |
R11482 | T15382 | T15379 | arg2Of | homogenized,: |
R11483 | T15382 | T15381 | arg2Of | homogenized,were |
R11484 | T15382 | T15383 | arg1Of | homogenized,with |
R11485 | T15386 | T15383 | arg2Of | homogenizer,with |
R11486 | T15386 | T15384 | arg1Of | homogenizer,a |
R11487 | T15386 | T15385 | arg1Of | homogenizer,Polytron |
R11488 | T15386 | T15387 | arg1Of | homogenizer,( |
R11489 | T15386 | T15390 | arg1Of | homogenizer,in |
R11490 | T15388 | T15387 | arg2Of | Kinematica,( |
R11491 | T15389 | T15387 | arg3Of | ),( |
R11492 | T15391 | T15390 | arg2Of | PBS,in |
R11493 | T15394 | T15392 | arg1Of | dilutions,Eight-fold |
R11494 | T15394 | T15393 | arg1Of | dilutions,serial |
R11495 | T15394 | T15395 | arg1Of | dilutions,of |
R11496 | T15394 | T15398 | arg1Of | dilutions,were |
R11497 | T15394 | T15399 | arg2Of | dilutions,incubated |
R11498 | T15397 | T15395 | arg2Of | homogenates,of |
R11499 | T15397 | T15396 | arg1Of | homogenates,lung |
R11500 | T15399 | T15398 | arg2Of | incubated,were |
R11501 | T15399 | T15400 | arg1Of | incubated,on |
R11502 | T15402 | T15400 | arg2Of | cells,on |
R11503 | T15402 | T15401 | arg1Of | cells,MDCK |
R11504 | T15402 | T15403 | arg1Of | cells,for |
R11505 | T15405 | T15403 | arg2Of | days,for |
R11506 | T15405 | T15404 | arg1Of | days,5 |
R11507 | T15405 | T15406 | arg1Of | days,in |
R11508 | T15405 | T15408 | arg2Of | days,supplemented |
R11509 | T15407 | T15406 | arg2Of | DMEM,in |
R11510 | T15408 | T15409 | arg1Of | supplemented,with |
R11511 | T15410 | T15411 | arg1Of | trypsin,( |
R11512 | T15410 | T15415 | arg1Of | trypsin,"," |
R11513 | T15413 | T15411 | arg2Of | µg/ml,( |
R11514 | T15413 | T15412 | arg1Of | µg/ml,1 |
R11515 | T15414 | T15411 | arg3Of | ),( |
R11516 | T15415 | T15419 | arg1Of | ",","," |
R11517 | T15416 | T15417 | arg1Of | 2,mM |
R11518 | T15418 | T15415 | arg2Of | L-glutamine,"," |
R11519 | T15418 | T15416 | arg1Of | L-glutamine,2 |
R11520 | T15419 | T15424 | arg1Of | ",",and |
R11521 | T15420 | T15421 | arg1Of | 0.4,mM |
R11522 | T15423 | T15419 | arg2Of | pyruvate,"," |
R11523 | T15423 | T15420 | arg1Of | pyruvate,0.4 |
R11524 | T15423 | T15422 | arg1Of | pyruvate,sodium |
R11525 | T15424 | T15409 | arg2Of | and,with |
R11526 | T15425 | T15424 | arg2Of | antibiotics,and |
R11527 | T15427 | T15426 | arg2Of | read-out,For |
R11528 | T15429 | T15430 | arg1Of | 0.5,% |
R11529 | T15434 | T15429 | arg1Of | cells,0.5 |
R11530 | T15434 | T15431 | arg1Of | cells,chicken |
R11531 | T15434 | T15432 | arg1Of | cells,red |
R11532 | T15434 | T15433 | arg1Of | cells,blood |
R11533 | T15434 | T15435 | arg1Of | cells,( |
R11534 | T15434 | T15438 | arg1Of | cells,were |
R11535 | T15434 | T15439 | arg2Of | cells,added |
R11536 | T15436 | T15435 | arg2Of | RBC,( |
R11537 | T15437 | T15435 | arg3Of | ),( |
R11538 | T15439 | T15438 | arg2Of | added,were |
R11539 | T15439 | T15440 | arg1Of | added,and |
R11540 | T15440 | T15426 | arg1Of | and,For |
R11541 | T15440 | T15428 | arg1Of | and,"," |
R11542 | T15442 | T15441 | arg1Of | dilution,end-point |
R11543 | T15442 | T15443 | arg1Of | dilution,of |
R11544 | T15442 | T15445 | arg1Of | dilution,was |
R11545 | T15442 | T15446 | arg2Of | dilution,monitored |
R11546 | T15444 | T15443 | arg2Of | hemagglutination,of |
R11547 | T15446 | T15440 | arg2Of | monitored,and |
R11548 | T15446 | T15445 | arg2Of | monitored,was |
R11549 | T15448 | T15447 | arg1Of | titers,TCID50 |
R11550 | T15448 | T15449 | arg1Of | titers,were |
R11551 | T15448 | T15451 | arg2Of | titers,calculated |
R11552 | T15451 | T15449 | arg2Of | calculated,were |
R11553 | T15451 | T15450 | arg1Of | calculated,then |
R11554 | T15451 | T15452 | arg1Of | calculated,according |
R11555 | T15453 | T15452 | arg2Of | to,according |
R11556 | T15455 | T15453 | arg2Of | method,to |
R11557 | T15455 | T15454 | arg1Of | method,the |
R11558 | T15455 | T15456 | arg1Of | method,of |
R11559 | T15457 | T15458 | arg1Of | Reed,and |
R11560 | T15458 | T15456 | arg2Of | and,of |
R11561 | T15459 | T15458 | arg2Of | Muench,and |
R11562 | T15459 | T15460 | arg1Of | Muench,[ |
R11563 | T15461 | T15460 | arg2Of | 85,[ |
R11564 | T15462 | T15460 | arg3Of | ],[ |
UBERON-AE
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T15281 | 797-802 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
T15280 | 606-610 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T15279 | 503-508 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lungs |
T15278 | 438-444 | http://purl.obolibrary.org/obo/UBERON_0000479 | denotes | tissue |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T15290 | 0-15 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | Viral infection |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T15294 | 803-808 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T15293 | 646-651 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T15292 | 124-129 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T15289 | 884-967 | Sentence | denotes | TCID50 titers were then calculated according to the method of Reed and Muench [85]. |
T15288 | 766-883 | Sentence | denotes | For read-out, 0.5% chicken red blood cells (RBC) were added and end-point dilution of hemagglutination was monitored. |
T15287 | 575-765 | Sentence | denotes | Eight-fold serial dilutions of lung homogenates were incubated on MDCK cells for 5 days in DMEM supplemented with trypsin (1 µg/ml), 2 mM L-glutamine, 0.4 mM sodium pyruvate and antibiotics. |
T15286 | 394-574 | Sentence | denotes | To determine pulmonary viral titers, median tissue culture infectious dose (TCID50) was measured as follows: lungs were homogenized with a Polytron homogenizer (Kinematica) in PBS. |
T15285 | 305-393 | Sentence | denotes | For lethal and sublethal infection, mice received respectively 2-LD50 or 0.05-LD50 X-47. |
T15284 | 131-304 | Sentence | denotes | For viral inoculation, mice were anesthetized by i.p. injection with ketamine (12 mg/kg) and xylazine (60 mg/kg) and 50 µl X-47 diluted in PBS was administered intranasally. |
T15283 | 50-130 | Sentence | denotes | Mouse adapted IAV X-47 (H3N2; PR8×A/Victoria/3/75) was propagated in MDCK cells. |
T15282 | 0-49 | Sentence | denotes | Viral infection and determination of viral titers |
T209 | 0-49 | Sentence | denotes | Viral infection and determination of viral titers |
T210 | 50-130 | Sentence | denotes | Mouse adapted IAV X-47 (H3N2; PR8×A/Victoria/3/75) was propagated in MDCK cells. |
T211 | 131-304 | Sentence | denotes | For viral inoculation, mice were anesthetized by i.p. injection with ketamine (12 mg/kg) and xylazine (60 mg/kg) and 50 µl X-47 diluted in PBS was administered intranasally. |
T212 | 305-393 | Sentence | denotes | For lethal and sublethal infection, mice received respectively 2-LD50 or 0.05-LD50 X-47. |
T213 | 394-574 | Sentence | denotes | To determine pulmonary viral titers, median tissue culture infectious dose (TCID50) was measured as follows: lungs were homogenized with a Polytron homogenizer (Kinematica) in PBS. |
T214 | 575-765 | Sentence | denotes | Eight-fold serial dilutions of lung homogenates were incubated on MDCK cells for 5 days in DMEM supplemented with trypsin (1 µg/ml), 2 mM L-glutamine, 0.4 mM sodium pyruvate and antibiotics. |
T215 | 766-883 | Sentence | denotes | For read-out, 0.5% chicken red blood cells (RBC) were added and end-point dilution of hemagglutination was monitored. |
T216 | 884-967 | Sentence | denotes | TCID50 titers were then calculated according to the method of Reed and Muench [85]. |
ICD10
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T15291 | 0-15 | http://purl.bioontology.org/ontology/ICD10/B34.9 | denotes | Viral infection |
bionlp-st-ge-2016-test-ihmc
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T15656 | 641-696 | Entity | denotes | MDCK cells for 5 days in DMEM supplemented with trypsin |
T15655 | 708-724 | Entity | denotes | 2 mM L-glutamine |
T15654 | 726-748 | Entity | denotes | 0.4 mM sodium pyruvate |
T15653 | 780-814 | Entity | denotes | 0.5% chicken red blood cells (RBC) |
T15652 | 810-813 | Entity | denotes | RBC |
T15651 | 154-158 | Protein | denotes | mice |
T15650 | 689-696 | Entity | denotes | trypsin |
T15649 | 341-345 | Protein | denotes | mice |
T15648 | 200-219 | Entity | denotes | ketamine (12 mg/kg) |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T15575 | 628-637 | VBN | denotes | incubated |
T15574 | 623-627 | VBD | denotes | were |
T15573 | 611-622 | NNS | denotes | homogenates |
T15572 | 606-610 | NN | denotes | lung |
T15571 | 603-605 | IN | denotes | of |
T15570 | 593-602 | NNS | denotes | dilutions |
T15569 | 586-592 | JJ | denotes | serial |
T15568 | 575-585 | JJ | denotes | Eight-fold |
T15567 | 573-574 | . | denotes | . |
T15566 | 570-573 | NNP | denotes | PBS |
T15565 | 567-569 | IN | denotes | in |
T15564 | 565-566 | -RRB- | denotes | ) |
T15563 | 555-565 | NNP | denotes | Kinematica |
T15562 | 554-555 | -LRB- | denotes | ( |
T15561 | 542-553 | NN | denotes | homogenizer |
T15560 | 533-541 | NNP | denotes | Polytron |
T15559 | 531-532 | DT | denotes | a |
T15558 | 526-530 | IN | denotes | with |
T15557 | 514-525 | VBN | denotes | homogenized |
T15556 | 509-513 | VBD | denotes | were |
T15555 | 503-508 | NNS | denotes | lungs |
T15554 | 501-502 | : | denotes | : |
T15553 | 494-501 | VBZ | denotes | follows |
T15552 | 491-493 | IN | denotes | as |
T15551 | 482-490 | VBN | denotes | measured |
T15550 | 478-481 | VBD | denotes | was |
T15549 | 476-477 | -RRB- | denotes | ) |
T15548 | 470-476 | CD | denotes | TCID50 |
T15547 | 469-470 | -LRB- | denotes | ( |
T15546 | 464-468 | NN | denotes | dose |
T15545 | 453-463 | JJ | denotes | infectious |
T15544 | 445-452 | NN | denotes | culture |
T15543 | 438-444 | NN | denotes | tissue |
T15542 | 431-437 | JJ | denotes | median |
T15504 | 218-219 | -RRB- | denotes | ) |
T15503 | 213-218 | NN | denotes | mg/kg |
T15502 | 210-212 | CD | denotes | 12 |
T15501 | 209-210 | -LRB- | denotes | ( |
T15500 | 200-208 | NN | denotes | ketamine |
T15499 | 195-199 | IN | denotes | with |
T15498 | 185-194 | NN | denotes | injection |
T15497 | 180-184 | JJ | denotes | i.p. |
T15496 | 177-179 | IN | denotes | by |
T15495 | 164-176 | JJ | denotes | anesthetized |
T15494 | 159-163 | VBD | denotes | were |
T15493 | 154-158 | NNS | denotes | mice |
T15492 | 152-153 | , | denotes | , |
T15491 | 141-152 | NN | denotes | inoculation |
T15490 | 135-140 | JJ | denotes | viral |
T15489 | 131-134 | IN | denotes | For |
T15488 | 129-130 | . | denotes | . |
T15487 | 124-129 | NNS | denotes | cells |
T15486 | 119-123 | NNP | denotes | MDCK |
T15485 | 116-118 | IN | denotes | in |
T15643 | 966-967 | . | denotes | . |
T15642 | 965-966 | NNP | denotes | ] |
T15641 | 963-965 | CD | denotes | 85 |
T15640 | 962-963 | NNP | denotes | [ |
T15639 | 955-961 | NNP | denotes | Muench |
T15638 | 951-954 | CC | denotes | and |
T15637 | 946-950 | NNP | denotes | Reed |
T15636 | 943-945 | IN | denotes | of |
T15635 | 936-942 | NN | denotes | method |
T15634 | 932-935 | DT | denotes | the |
T15633 | 929-931 | TO | denotes | to |
T15632 | 919-928 | VBG | denotes | according |
T15631 | 908-918 | VBN | denotes | calculated |
T15630 | 903-907 | RB | denotes | then |
T15629 | 898-902 | VBD | denotes | were |
T15628 | 891-897 | NNS | denotes | titers |
T15627 | 884-890 | CD | denotes | TCID50 |
T15626 | 882-883 | . | denotes | . |
T15625 | 873-882 | VBN | denotes | monitored |
T15624 | 869-872 | VBD | denotes | was |
T15623 | 852-868 | NN | denotes | hemagglutination |
T15622 | 849-851 | IN | denotes | of |
T15621 | 840-848 | NN | denotes | dilution |
T15620 | 830-839 | JJ | denotes | end-point |
T15619 | 826-829 | CC | denotes | and |
T15618 | 820-825 | VBN | denotes | added |
T15617 | 815-819 | VBD | denotes | were |
T15616 | 813-814 | -RRB- | denotes | ) |
T15615 | 810-813 | NNP | denotes | RBC |
T15614 | 809-810 | -LRB- | denotes | ( |
T15613 | 803-808 | NNS | denotes | cells |
T15612 | 797-802 | NN | denotes | blood |
T15611 | 793-796 | JJ | denotes | red |
T15610 | 785-792 | NN | denotes | chicken |
T15609 | 783-784 | NN | denotes | % |
T15608 | 780-783 | CD | denotes | 0.5 |
T15607 | 778-779 | , | denotes | , |
T15606 | 770-778 | JJ | denotes | read-out |
T15605 | 766-769 | IN | denotes | For |
T15604 | 764-765 | . | denotes | . |
T15603 | 753-764 | NNS | denotes | antibiotics |
T15602 | 749-752 | CC | denotes | and |
T15601 | 740-748 | NN | denotes | pyruvate |
T15600 | 733-739 | NN | denotes | sodium |
T15599 | 730-732 | NNP | denotes | mM |
T15598 | 726-729 | CD | denotes | 0.4 |
T15597 | 724-725 | , | denotes | , |
T15596 | 713-724 | NNP | denotes | L-glutamine |
T15595 | 710-712 | NNP | denotes | mM |
T15594 | 708-709 | CD | denotes | 2 |
T15593 | 706-707 | , | denotes | , |
T15592 | 705-706 | -RRB- | denotes | ) |
T15591 | 703-705 | NN | denotes | ml |
T15590 | 702-703 | NN | denotes | / |
T15589 | 700-702 | NN | denotes | µg |
T15588 | 698-699 | CD | denotes | 1 |
T15587 | 697-698 | -LRB- | denotes | ( |
T15586 | 689-696 | NN | denotes | trypsin |
T15585 | 684-688 | IN | denotes | with |
T15584 | 671-683 | VBN | denotes | supplemented |
T15583 | 666-670 | NNP | denotes | DMEM |
T15582 | 663-665 | IN | denotes | in |
T15581 | 658-662 | NNS | denotes | days |
T15580 | 656-657 | CD | denotes | 5 |
T15579 | 652-655 | IN | denotes | for |
T15578 | 646-651 | NNS | denotes | cells |
T15577 | 641-645 | NNP | denotes | MDCK |
T15576 | 638-640 | IN | denotes | on |
T15522 | 305-308 | IN | denotes | For |
T15521 | 303-304 | . | denotes | . |
T15520 | 291-303 | RB | denotes | intranasally |
T15519 | 278-290 | VBN | denotes | administered |
T15518 | 274-277 | VBD | denotes | was |
T15484 | 105-115 | VBN | denotes | propagated |
T15483 | 101-104 | VBD | denotes | was |
T15482 | 99-100 | -RRB- | denotes | ) |
T15481 | 97-99 | CD | denotes | 75 |
T15480 | 96-97 | VBD | denotes | / |
T15479 | 84-96 | NNP | denotes | A/Victoria/3 |
T15478 | 83-84 | NNP | denotes | × |
T15477 | 80-83 | NNP | denotes | PR8 |
T15476 | 78-79 | : | denotes | ; |
T15475 | 74-78 | NNP | denotes | H3N2 |
T15474 | 73-74 | -LRB- | denotes | ( |
T15473 | 68-72 | NNP | denotes | X-47 |
T15472 | 64-67 | NNP | denotes | IAV |
T15471 | 56-63 | VBD | denotes | adapted |
T15470 | 50-55 | NNP | denotes | Mouse |
T15469 | 43-49 | NNS | denotes | titers |
T15468 | 37-42 | JJ | denotes | viral |
T15467 | 34-36 | IN | denotes | of |
T15466 | 20-33 | NN | denotes | determination |
T15465 | 16-19 | CC | denotes | and |
T15464 | 6-15 | NN | denotes | infection |
T15463 | 0-5 | JJ | denotes | Viral |
T15541 | 429-430 | , | denotes | , |
T15540 | 423-429 | NNS | denotes | titers |
T15539 | 417-422 | JJ | denotes | viral |
T15538 | 407-416 | JJ | denotes | pulmonary |
T15537 | 397-406 | VB | denotes | determine |
T15536 | 394-396 | TO | denotes | To |
T15535 | 392-393 | . | denotes | . |
T15534 | 388-392 | NNP | denotes | X-47 |
T15533 | 378-387 | JJ | denotes | 0.05-LD50 |
T15532 | 375-377 | CC | denotes | or |
T15531 | 368-374 | JJ | denotes | 2-LD50 |
T15530 | 355-367 | RB | denotes | respectively |
T15529 | 346-354 | VBD | denotes | received |
T15528 | 341-345 | NNS | denotes | mice |
T15527 | 339-340 | , | denotes | , |
T15526 | 330-339 | NN | denotes | infection |
T15525 | 320-329 | JJ | denotes | sublethal |
T15524 | 316-319 | CC | denotes | and |
T15523 | 309-315 | JJ | denotes | lethal |
T15517 | 270-273 | NNP | denotes | PBS |
T15516 | 267-269 | IN | denotes | in |
T15515 | 259-266 | VBN | denotes | diluted |
T15514 | 254-258 | NNP | denotes | X-47 |
T15513 | 251-253 | NN | denotes | µl |
T15512 | 248-250 | CD | denotes | 50 |
T15511 | 244-247 | CC | denotes | and |
T15510 | 242-243 | -RRB- | denotes | ) |
T15509 | 237-242 | NN | denotes | mg/kg |
T15508 | 234-236 | CD | denotes | 60 |
T15507 | 233-234 | -LRB- | denotes | ( |
T15506 | 224-232 | NN | denotes | xylazine |
T15505 | 220-223 | CC | denotes | and |
R11578 | T15476 | T15473 | punct | ;,X-47 |
R11579 | T15477 | T15479 | compound | PR8,A/Victoria/3 |
R11580 | T15478 | T15479 | compound | ×,A/Victoria/3 |
R11581 | T15479 | T15480 | nsubj | A/Victoria/3,/ |
R11582 | T15480 | T15471 | parataxis | /,adapted |
R11583 | T15481 | T15480 | npadvmod | 75,/ |
R11584 | T15482 | T15480 | punct | ),/ |
R11585 | T15483 | T15484 | auxpass | was,propagated |
R11586 | T15484 | T15471 | conj | propagated,adapted |
R11587 | T15485 | T15484 | prep | in,propagated |
R11588 | T15486 | T15487 | compound | MDCK,cells |
R11589 | T15487 | T15485 | pobj | cells,in |
R11590 | T15488 | T15471 | punct | .,adapted |
R11591 | T15489 | T15495 | prep | For,anesthetized |
R11592 | T15490 | T15491 | amod | viral,inoculation |
R11593 | T15491 | T15489 | pobj | inoculation,For |
R11594 | T15492 | T15495 | punct | ",",anesthetized |
R11595 | T15493 | T15495 | nsubjpass | mice,anesthetized |
R11596 | T15494 | T15495 | auxpass | were,anesthetized |
R11597 | T15495 | T15495 | ROOT | anesthetized,anesthetized |
R11598 | T15496 | T15495 | agent | by,anesthetized |
R11599 | T15497 | T15498 | amod | i.p.,injection |
R11600 | T15498 | T15514 | nmod | injection,X-47 |
R11601 | T15499 | T15498 | prep | with,injection |
R11602 | T15500 | T15499 | pobj | ketamine,with |
R11603 | T15501 | T15503 | punct | (,mg/kg |
R11604 | T15502 | T15503 | nummod | 12,mg/kg |
R11605 | T15503 | T15514 | nmod | mg/kg,X-47 |
R11606 | T15504 | T15503 | punct | ),mg/kg |
R11607 | T15505 | T15503 | cc | and,mg/kg |
R11608 | T15506 | T15503 | conj | xylazine,mg/kg |
R11609 | T15507 | T15506 | punct | (,xylazine |
R11610 | T15508 | T15509 | nummod | 60,mg/kg |
R11611 | T15509 | T15506 | appos | mg/kg,xylazine |
R11612 | T15510 | T15509 | punct | ),mg/kg |
R11613 | T15511 | T15506 | cc | and,xylazine |
R11614 | T15512 | T15513 | nummod | 50,µl |
R11615 | T15513 | T15514 | compound | µl,X-47 |
R11616 | T15514 | T15496 | pobj | X-47,by |
R11617 | T15515 | T15514 | amod | diluted,X-47 |
R11618 | T15516 | T15515 | prep | in,diluted |
R11619 | T15517 | T15516 | pobj | PBS,in |
R11620 | T15518 | T15519 | auxpass | was,administered |
R11621 | T15519 | T15495 | conj | administered,anesthetized |
R11622 | T15520 | T15519 | advmod | intranasally,administered |
R11623 | T15521 | T15519 | punct | .,administered |
R11624 | T15522 | T15529 | prep | For,received |
R11625 | T15523 | T15526 | amod | lethal,infection |
R11652 | T15550 | T15551 | auxpass | was,measured |
R11653 | T15551 | T15557 | ccomp | measured,homogenized |
R11654 | T15552 | T15553 | mark | as,follows |
R11655 | T15553 | T15551 | advcl | follows,measured |
R11656 | T15554 | T15557 | punct | :,homogenized |
R11657 | T15555 | T15556 | nsubj | lungs,were |
R11658 | T15556 | T15557 | auxpass | were,homogenized |
R11659 | T15557 | T15557 | ROOT | homogenized,homogenized |
R11660 | T15558 | T15557 | prep | with,homogenized |
R11661 | T15559 | T15561 | det | a,homogenizer |
R11662 | T15560 | T15561 | compound | Polytron,homogenizer |
R11663 | T15561 | T15558 | pobj | homogenizer,with |
R11664 | T15562 | T15561 | punct | (,homogenizer |
R11665 | T15563 | T15561 | appos | Kinematica,homogenizer |
R11666 | T15564 | T15561 | punct | ),homogenizer |
R11667 | T15565 | T15557 | prep | in,homogenized |
R11668 | T15566 | T15565 | pobj | PBS,in |
R11669 | T15567 | T15557 | punct | .,homogenized |
R11670 | T15568 | T15570 | amod | Eight-fold,dilutions |
R11671 | T15569 | T15570 | amod | serial,dilutions |
R11672 | T15570 | T15575 | nsubjpass | dilutions,incubated |
R11673 | T15571 | T15570 | prep | of,dilutions |
R11674 | T15572 | T15573 | compound | lung,homogenates |
R11675 | T15573 | T15571 | pobj | homogenates,of |
R11676 | T15574 | T15575 | auxpass | were,incubated |
R11677 | T15575 | T15575 | ROOT | incubated,incubated |
R11678 | T15576 | T15575 | prep | on,incubated |
R11679 | T15577 | T15578 | compound | MDCK,cells |
R11680 | T15578 | T15576 | pobj | cells,on |
R11681 | T15579 | T15575 | prep | for,incubated |
R11682 | T15580 | T15581 | nummod | 5,days |
R11683 | T15581 | T15579 | pobj | days,for |
R11684 | T15582 | T15581 | prep | in,days |
R11685 | T15583 | T15582 | pobj | DMEM,in |
R11686 | T15584 | T15575 | conj | supplemented,incubated |
R11687 | T15585 | T15584 | prep | with,supplemented |
R11688 | T15586 | T15585 | pobj | trypsin,with |
R11689 | T15587 | T15591 | punct | (,ml |
R11690 | T15588 | T15589 | nummod | 1,µg |
R11691 | T15589 | T15591 | nmod | µg,ml |
R11692 | T15590 | T15591 | compound | /,ml |
R11693 | T15591 | T15586 | appos | ml,trypsin |
R11694 | T15592 | T15591 | punct | ),ml |
R11695 | T15593 | T15586 | punct | ",",trypsin |
R11696 | T15594 | T15596 | nummod | 2,L-glutamine |
R11697 | T15595 | T15596 | compound | mM,L-glutamine |
R11698 | T15596 | T15586 | appos | L-glutamine,trypsin |
R11699 | T15597 | T15596 | punct | ",",L-glutamine |
R11700 | T15598 | T15601 | nummod | 0.4,pyruvate |
R11701 | T15599 | T15601 | compound | mM,pyruvate |
R11702 | T15600 | T15601 | compound | sodium,pyruvate |
R11703 | T15601 | T15596 | appos | pyruvate,L-glutamine |
R11704 | T15602 | T15601 | cc | and,pyruvate |
R11705 | T15603 | T15601 | conj | antibiotics,pyruvate |
R11706 | T15604 | T15575 | punct | .,incubated |
R11707 | T15605 | T15618 | prep | For,added |
R11708 | T15606 | T15605 | pobj | read-out,For |
R11709 | T15607 | T15618 | punct | ",",added |
R11710 | T15608 | T15609 | nummod | 0.5,% |
R11711 | T15609 | T15618 | nsubjpass | %,added |
R11712 | T15610 | T15613 | amod | chicken,cells |
R11713 | T15611 | T15613 | amod | red,cells |
R11714 | T15612 | T15613 | compound | blood,cells |
R11715 | T15613 | T15609 | appos | cells,% |
R11716 | T15614 | T15615 | punct | (,RBC |
R11717 | T15615 | T15613 | appos | RBC,cells |
R11718 | T15616 | T15613 | punct | ),cells |
R11719 | T15617 | T15618 | auxpass | were,added |
R11720 | T15618 | T15618 | ROOT | added,added |
R11721 | T15619 | T15618 | cc | and,added |
R11722 | T15620 | T15618 | conj | end-point,added |
R11723 | T15621 | T15625 | nsubjpass | dilution,monitored |
R11724 | T15622 | T15621 | prep | of,dilution |
R11725 | T15623 | T15622 | pobj | hemagglutination,of |
R11726 | T15624 | T15625 | auxpass | was,monitored |
R11727 | T15625 | T15618 | conj | monitored,added |
R11728 | T15626 | T15625 | punct | .,monitored |
R11729 | T15627 | T15628 | nummod | TCID50,titers |
R11730 | T15628 | T15631 | nsubjpass | titers,calculated |
R11731 | T15629 | T15631 | auxpass | were,calculated |
R11732 | T15630 | T15631 | advmod | then,calculated |
R11733 | T15631 | T15631 | ROOT | calculated,calculated |
R11734 | T15632 | T15631 | prep | according,calculated |
R11735 | T15633 | T15632 | prep | to,according |
R11736 | T15634 | T15635 | det | the,method |
R11737 | T15635 | T15633 | pobj | method,to |
R11738 | T15636 | T15635 | prep | of,method |
R11739 | T15637 | T15636 | pobj | Reed,of |
R11740 | T15638 | T15637 | cc | and,Reed |
R11741 | T15639 | T15640 | compound | Muench,[ |
R11742 | T15640 | T15637 | conj | [,Reed |
R11743 | T15641 | T15642 | nummod | 85,] |
R11744 | T15642 | T15635 | appos | ],method |
R11745 | T15643 | T15631 | punct | .,calculated |
R11565 | T15463 | T15464 | amod | Viral,infection |
R11566 | T15464 | T15471 | nsubj | infection,adapted |
R11567 | T15465 | T15464 | cc | and,infection |
R11568 | T15466 | T15464 | conj | determination,infection |
R11569 | T15467 | T15466 | prep | of,determination |
R11570 | T15468 | T15469 | amod | viral,titers |
R11571 | T15469 | T15467 | pobj | titers,of |
R11572 | T15470 | T15471 | nsubj | Mouse,adapted |
R11573 | T15471 | T15471 | ROOT | adapted,adapted |
R11574 | T15472 | T15473 | compound | IAV,X-47 |
R11575 | T15473 | T15471 | dobj | X-47,adapted |
R11576 | T15474 | T15475 | punct | (,H3N2 |
R11577 | T15475 | T15473 | appos | H3N2,X-47 |
R11626 | T15524 | T15523 | cc | and,lethal |
R11627 | T15525 | T15523 | conj | sublethal,lethal |
R11628 | T15526 | T15522 | pobj | infection,For |
R11629 | T15527 | T15529 | punct | ",",received |
R11630 | T15528 | T15529 | nsubj | mice,received |
R11631 | T15529 | T15529 | ROOT | received,received |
R11632 | T15530 | T15531 | advmod | respectively,2-LD50 |
R11633 | T15531 | T15534 | amod | 2-LD50,X-47 |
R11634 | T15532 | T15531 | cc | or,2-LD50 |
R11635 | T15533 | T15531 | conj | 0.05-LD50,2-LD50 |
R11636 | T15534 | T15529 | dobj | X-47,received |
R11637 | T15535 | T15529 | punct | .,received |
R11638 | T15536 | T15537 | aux | To,determine |
R11639 | T15537 | T15551 | advcl | determine,measured |
R11640 | T15538 | T15540 | amod | pulmonary,titers |
R11641 | T15539 | T15540 | amod | viral,titers |
R11642 | T15540 | T15537 | dobj | titers,determine |
R11643 | T15541 | T15540 | punct | ",",titers |
R11644 | T15542 | T15544 | amod | median,culture |
R11645 | T15543 | T15544 | compound | tissue,culture |
R11646 | T15544 | T15540 | appos | culture,titers |
R11647 | T15545 | T15546 | amod | infectious,dose |
R11648 | T15546 | T15540 | appos | dose,titers |
R11649 | T15547 | T15546 | punct | (,dose |
R11650 | T15548 | T15546 | appos | TCID50,dose |
R11651 | T15549 | T15546 | punct | ),dose |
bionlp-st-ge-2016-test-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T15645 | 689-696 | Protein | denotes | trypsin |
T15644 | 119-123 | Protein | denotes | MDCK |