PMC:3279418 / 189-495 JSONTXT

{"project":"pmc-enju-pas","denotations":[{"id":"T420","span":{"begin":1,"end":4},"obj":"DT"},{"id":"T421","span":{"begin":5,"end":12},"obj":"NNP"},{"id":"T422","span":{"begin":13,"end":14},"obj":"-LRB-"},{"id":"T423","span":{"begin":14,"end":30},"obj":"JJ"},{"id":"T424","span":{"begin":31,"end":33},"obj":"NN"},{"id":"T425","span":{"begin":34,"end":52},"obj":"JJ"},{"id":"T426","span":{"begin":53,"end":60},"obj":"NN"},{"id":"T427","span":{"begin":60,"end":61},"obj":"-COMMA-"},{"id":"T428","span":{"begin":62,"end":67},"obj":"JJ"},{"id":"T429","span":{"begin":68,"end":75},"obj":"NN"},{"id":"T430","span":{"begin":75,"end":76},"obj":"-COLON-"},{"id":"T431","span":{"begin":77,"end":83},"obj":"NN"},{"id":"T432","span":{"begin":83,"end":84},"obj":"-COMMA-"},{"id":"T433","span":{"begin":85,"end":90},"obj":"NN"},{"id":"T434","span":{"begin":90,"end":91},"obj":"-RRB-"},{"id":"T435","span":{"begin":92,"end":96},"obj":"NN"},{"id":"T436","span":{"begin":97,"end":99},"obj":"IN"},{"id":"T437","span":{"begin":100,"end":104},"obj":"NN"},{"id":"T438","span":{"begin":105,"end":111},"obj":"VB"},{"id":"T439","span":{"begin":112,"end":114},"obj":"IN"},{"id":"T440","span":{"begin":115,"end":123},"obj":"JJ"},{"id":"T441","span":{"begin":124,"end":136},"obj":"NN"},{"id":"T442","span":{"begin":137,"end":141},"obj":"WDT"},{"id":"T443","span":{"begin":142,"end":144},"obj":"VB"},{"id":"T444","span":{"begin":145,"end":158},"obj":"VB"},{"id":"T445","span":{"begin":159,"end":161},"obj":"IN"},{"id":"T446","span":{"begin":162,"end":169},"obj":"JJ"},{"id":"T447","span":{"begin":170,"end":183},"obj":"JJ"},{"id":"T448","span":{"begin":184,"end":194},"obj":"NN"},{"id":"T449","span":{"begin":195,"end":198},"obj":"CC"},{"id":"T450","span":{"begin":199,"end":211},"obj":"VB"},{"id":"T451","span":{"begin":212,"end":221},"obj":"NN"},{"id":"T452","span":{"begin":222,"end":224},"obj":"IN"},{"id":"T453","span":{"begin":225,"end":226},"obj":"NN"},{"id":"T454","span":{"begin":227,"end":234},"obj":"NN"},{"id":"T455","span":{"begin":235,"end":236},"obj":"-LRB-"},{"id":"T456","span":{"begin":236,"end":239},"obj":"NN"},{"id":"T457","span":{"begin":239,"end":240},"obj":"-RRB-"},{"id":"T458","span":{"begin":241,"end":244},"obj":"CC"},{"id":"T459","span":{"begin":245,"end":248},"obj":"NN"},{"id":"T460","span":{"begin":249,"end":258},"obj":"NN"},{"id":"T461","span":{"begin":260,"end":263},"obj":"DT"},{"id":"T462","span":{"begin":264,"end":272},"obj":"JJ"},{"id":"T463","span":{"begin":273,"end":276},"obj":"CC"},{"id":"T464","span":{"begin":277,"end":286},"obj":"JJ"},{"id":"T465","span":{"begin":287,"end":297},"obj":"NN"}],"relations":[{"id":"R336","pred":"arg1Of","subj":"T426","obj":"T420"},{"id":"R337","pred":"arg1Of","subj":"T426","obj":"T421"},{"id":"R338","pred":"arg1Of","subj":"T426","obj":"T422"},{"id":"R339","pred":"arg1Of","subj":"T426","obj":"T423"},{"id":"R340","pred":"arg1Of","subj":"T426","obj":"T424"},{"id":"R341","pred":"arg1Of","subj":"T426","obj":"T425"},{"id":"R342","pred":"arg1Of","subj":"T426","obj":"T427"},{"id":"R343","pred":"arg2Of","subj":"T429","obj":"T427"},{"id":"R344","pred":"arg1Of","subj":"T429","obj":"T428"},{"id":"R345","pred":"arg1Of","subj":"T429","obj":"T430"},{"id":"R346","pred":"arg1Of","subj":"T431","obj":"T432"},{"id":"R347","pred":"arg1Of","subj":"T431","obj":"T438"},{"id":"R348","pred":"arg2Of","subj":"T433","obj":"T432"},{"id":"R349","pred":"arg1Of","subj":"T433","obj":"T434"},{"id":"R350","pred":"arg1Of","subj":"T433","obj":"T435"},{"id":"R351","pred":"arg1Of","subj":"T433","obj":"T436"},{"id":"R352","pred":"arg2Of","subj":"T437","obj":"T436"},{"id":"R353","pred":"arg1Of","subj":"T438","obj":"T439"},{"id":"R354","pred":"arg2Of","subj":"T441","obj":"T439"},{"id":"R355","pred":"arg1Of","subj":"T441","obj":"T440"},{"id":"R356","pred":"arg1Of","subj":"T441","obj":"T442"},{"id":"R357","pred":"arg1Of","subj":"T441","obj":"T443"},{"id":"R358","pred":"arg2Of","subj":"T441","obj":"T444"},{"id":"R359","pred":"arg2Of","subj":"T444","obj":"T443"},{"id":"R360","pred":"arg1Of","subj":"T448","obj":"T446"},{"id":"R361","pred":"arg1Of","subj":"T448","obj":"T447"},{"id":"R362","pred":"arg1Of","subj":"T448","obj":"T449"},{"id":"R363","pred":"arg1Of","subj":"T449","obj":"T444"},{"id":"R364","pred":"arg2Of","subj":"T449","obj":"T445"},{"id":"R365","pred":"arg2Of","subj":"T451","obj":"T449"},{"id":"R366","pred":"arg2Of","subj":"T451","obj":"T450"},{"id":"R367","pred":"arg1Of","subj":"T451","obj":"T452"},{"id":"R368","pred":"arg1Of","subj":"T454","obj":"T453"},{"id":"R369","pred":"arg1Of","subj":"T454","obj":"T455"},{"id":"R370","pred":"arg1Of","subj":"T454","obj":"T458"},{"id":"R371","pred":"arg2Of","subj":"T456","obj":"T455"},{"id":"R372","pred":"arg3Of","subj":"T457","obj":"T455"},{"id":"R373","pred":"arg2Of","subj":"T459","obj":"T458"},{"id":"R374","pred":"arg2Of","subj":"T460","obj":"T452"},{"id":"R375","pred":"arg1Of","subj":"T460","obj":"T454"},{"id":"R376","pred":"arg1Of","subj":"T460","obj":"T459"},{"id":"R377","pred":"arg1Of","subj":"T462","obj":"T463"},{"id":"R378","pred":"arg2Of","subj":"T464","obj":"T463"},{"id":"R379","pred":"arg1Of","subj":"T465","obj":"T461"},{"id":"R380","pred":"arg1Of","subj":"T465","obj":"T462"},{"id":"R381","pred":"arg1Of","subj":"T465","obj":"T464"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"text":" the Sharpin (SHANK-associated RH domain-interacting protein, other aliases: Rbckl1, Sipl1) gene in mice result in systemic inflammation that is characterized by chronic proliferative dermatitis and dysregulated secretion of T helper1 (Th1) and Th2 cytokines. The cellular and molecular mechanisms underlyi"}

{"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T139","span":{"begin":1,"end":4},"obj":"DT"},{"id":"T140","span":{"begin":5,"end":12},"obj":"NNP"},{"id":"T141","span":{"begin":13,"end":14},"obj":"-LRB-"},{"id":"T142","span":{"begin":14,"end":30},"obj":"JJ"},{"id":"T143","span":{"begin":31,"end":33},"obj":"NNP"},{"id":"T144","span":{"begin":34,"end":52},"obj":"NN"},{"id":"T145","span":{"begin":53,"end":60},"obj":"NN"},{"id":"T146","span":{"begin":60,"end":61},"obj":","},{"id":"T147","span":{"begin":62,"end":67},"obj":"JJ"},{"id":"T148","span":{"begin":68,"end":75},"obj":"NNS"},{"id":"T149","span":{"begin":75,"end":76},"obj":":"},{"id":"T150","span":{"begin":77,"end":83},"obj":"NNS"},{"id":"T151","span":{"begin":83,"end":84},"obj":","},{"id":"T152","span":{"begin":85,"end":90},"obj":"NNP"},{"id":"T153","span":{"begin":90,"end":91},"obj":"-RRB-"},{"id":"T154","span":{"begin":92,"end":96},"obj":"NN"},{"id":"T155","span":{"begin":97,"end":99},"obj":"IN"},{"id":"T156","span":{"begin":100,"end":104},"obj":"NNS"},{"id":"T157","span":{"begin":105,"end":111},"obj":"VBP"},{"id":"T158","span":{"begin":112,"end":114},"obj":"IN"},{"id":"T159","span":{"begin":115,"end":123},"obj":"JJ"},{"id":"T160","span":{"begin":124,"end":136},"obj":"NN"},{"id":"T161","span":{"begin":137,"end":141},"obj":"WDT"},{"id":"T162","span":{"begin":142,"end":144},"obj":"VBZ"},{"id":"T163","span":{"begin":145,"end":158},"obj":"VBN"},{"id":"T164","span":{"begin":159,"end":161},"obj":"IN"},{"id":"T165","span":{"begin":162,"end":169},"obj":"JJ"},{"id":"T166","span":{"begin":170,"end":183},"obj":"JJ"},{"id":"T167","span":{"begin":184,"end":194},"obj":"NN"},{"id":"T168","span":{"begin":195,"end":198},"obj":"CC"},{"id":"T169","span":{"begin":199,"end":211},"obj":"VBD"},{"id":"T170","span":{"begin":212,"end":221},"obj":"NN"},{"id":"T171","span":{"begin":222,"end":224},"obj":"IN"},{"id":"T172","span":{"begin":225,"end":226},"obj":"NNP"},{"id":"T173","span":{"begin":227,"end":234},"obj":"CD"},{"id":"T174","span":{"begin":235,"end":236},"obj":"-LRB-"},{"id":"T175","span":{"begin":236,"end":239},"obj":"NN"},{"id":"T176","span":{"begin":239,"end":240},"obj":"-RRB-"},{"id":"T177","span":{"begin":241,"end":244},"obj":"CC"},{"id":"T178","span":{"begin":245,"end":248},"obj":"JJ"},{"id":"T179","span":{"begin":249,"end":258},"obj":"NNS"},{"id":"T180","span":{"begin":258,"end":259},"obj":"."},{"id":"T181","span":{"begin":260,"end":263},"obj":"DT"},{"id":"T182","span":{"begin":264,"end":272},"obj":"JJ"},{"id":"T183","span":{"begin":273,"end":276},"obj":"CC"},{"id":"T184","span":{"begin":277,"end":286},"obj":"JJ"},{"id":"T185","span":{"begin":287,"end":297},"obj":"NNS"}],"relations":[{"id":"R71","pred":"prep","subj":"T155","obj":"T154"},{"id":"R72","pred":"pobj","subj":"T156","obj":"T155"},{"id":"R74","pred":"prep","subj":"T158","obj":"T157"},{"id":"R75","pred":"amod","subj":"T159","obj":"T160"},{"id":"R76","pred":"pobj","subj":"T160","obj":"T158"},{"id":"R77","pred":"nsubjpass","subj":"T161","obj":"T163"},{"id":"R78","pred":"auxpass","subj":"T162","obj":"T163"},{"id":"R79","pred":"relcl","subj":"T163","obj":"T160"},{"id":"R80","pred":"agent","subj":"T164","obj":"T163"},{"id":"R81","pred":"amod","subj":"T165","obj":"T167"},{"id":"R82","pred":"compound","subj":"T166","obj":"T167"},{"id":"R83","pred":"pobj","subj":"T167","obj":"T164"},{"id":"R84","pred":"cc","subj":"T168","obj":"T167"},{"id":"R85","pred":"amod","subj":"T169","obj":"T170"},{"id":"R86","pred":"conj","subj":"T170","obj":"T167"},{"id":"R87","pred":"prep","subj":"T171","obj":"T170"},{"id":"R88","pred":"compound","subj":"T172","obj":"T173"},{"id":"R89","pred":"pobj","subj":"T173","obj":"T171"},{"id":"R90","pred":"punct","subj":"T174","obj":"T175"},{"id":"R91","pred":"appos","subj":"T175","obj":"T170"},{"id":"R92","pred":"punct","subj":"T176","obj":"T175"},{"id":"R93","pred":"cc","subj":"T177","obj":"T170"},{"id":"R94","pred":"amod","subj":"T178","obj":"T179"},{"id":"R95","pred":"conj","subj":"T179","obj":"T170"},{"id":"R96","pred":"punct","subj":"T180","obj":"T157"},{"id":"R97","pred":"det","subj":"T181","obj":"T185"},{"id":"R98","pred":"amod","subj":"T182","obj":"T185"},{"id":"R99","pred":"cc","subj":"T183","obj":"T182"},{"id":"R100","pred":"conj","subj":"T184","obj":"T182"},{"id":"R55","pred":"det","subj":"T139","obj":"T140"},{"id":"R57","pred":"punct","subj":"T141","obj":"T145"},{"id":"R58","pred":"amod","subj":"T142","obj":"T145"},{"id":"R59","pred":"compound","subj":"T143","obj":"T145"},{"id":"R60","pred":"compound","subj":"T144","obj":"T145"},{"id":"R61","pred":"appos","subj":"T145","obj":"T140"},{"id":"R62","pred":"punct","subj":"T146","obj":"T148"},{"id":"R63","pred":"amod","subj":"T147","obj":"T148"},{"id":"R65","pred":"punct","subj":"T149","obj":"T148"},{"id":"R66","pred":"conj","subj":"T150","obj":"T148"},{"id":"R67","pred":"punct","subj":"T151","obj":"T150"},{"id":"R68","pred":"nmod","subj":"T152","obj":"T154"},{"id":"R69","pred":"punct","subj":"T153","obj":"T152"},{"id":"R70","pred":"nsubj","subj":"T154","obj":"T157"}],"text":" the Sharpin (SHANK-associated RH domain-interacting protein, other aliases: Rbckl1, Sipl1) gene in mice result in systemic inflammation that is characterized by chronic proliferative dermatitis and dysregulated secretion of T helper1 (Th1) and Th2 cytokines. The cellular and molecular mechanisms underlyi"}

{"project":"GO-BP","denotations":[{"id":"T701","span":{"begin":124,"end":136},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T703","span":{"begin":212,"end":221},"obj":"http://purl.obolibrary.org/obo/GO_0046903"},{"id":"T705","span":{"begin":264,"end":272},"obj":"http://purl.obolibrary.org/obo/GO_0007349"}],"text":" the Sharpin (SHANK-associated RH domain-interacting protein, other aliases: Rbckl1, Sipl1) gene in mice result in systemic inflammation that is characterized by chronic proliferative dermatitis and dysregulated secretion of T helper1 (Th1) and Th2 cytokines. The cellular and molecular mechanisms underlyi"}

{"project":"sentences","denotations":[{"id":"T109","span":{"begin":77,"end":259},"obj":"Sentence"},{"id":"T4","span":{"begin":77,"end":259},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":" the Sharpin (SHANK-associated RH domain-interacting protein, other aliases: Rbckl1, Sipl1) gene in mice result in systemic inflammation that is characterized by chronic proliferative dermatitis and dysregulated secretion of T helper1 (Th1) and Th2 cytokines. The cellular and molecular mechanisms underlyi"}

{"project":"ICD10","denotations":[{"id":"T723","span":{"begin":184,"end":194},"obj":"http://purl.bioontology.org/ontology/ICD10/L30.9"}],"text":" the Sharpin (SHANK-associated RH domain-interacting protein, other aliases: Rbckl1, Sipl1) gene in mice result in systemic inflammation that is characterized by chronic proliferative dermatitis and dysregulated secretion of T helper1 (Th1) and Th2 cytokines. The cellular and molecular mechanisms underlyi"}

{"project":"events-check-again","denotations":[{"id":"T804","span":{"begin":5,"end":12},"obj":"Protein"},{"id":"T805","span":{"begin":14,"end":60},"obj":"Protein"},{"id":"T806","span":{"begin":77,"end":83},"obj":"Protein"},{"id":"T807","span":{"begin":85,"end":90},"obj":"Protein"}],"relations":[{"id":"R695","pred":"equivalentTo","subj":"T805","obj":"T804"},{"id":"R696","pred":"equivalentTo","subj":"T806","obj":"T804"},{"id":"R697","pred":"equivalentTo","subj":"T807","obj":"T804"}],"text":" the Sharpin (SHANK-associated RH domain-interacting protein, other aliases: Rbckl1, Sipl1) gene in mice result in systemic inflammation that is characterized by chronic proliferative dermatitis and dysregulated secretion of T helper1 (Th1) and Th2 cytokines. The cellular and molecular mechanisms underlyi"}

{"project":"bionlp-st-ge-2016-reference-tees","denotations":[{"id":"T840","span":{"begin":5,"end":12},"obj":"Protein"},{"id":"T841","span":{"begin":14,"end":19},"obj":"Protein"},{"id":"T842","span":{"begin":31,"end":33},"obj":"Protein"},{"id":"T843","span":{"begin":77,"end":83},"obj":"Protein"},{"id":"T844","span":{"begin":85,"end":90},"obj":"Protein"},{"id":"T845","span":{"begin":225,"end":234},"obj":"Protein"},{"id":"T846","span":{"begin":236,"end":239},"obj":"Protein"},{"id":"T851","span":{"begin":20,"end":30},"obj":"Gene_expression"},{"id":"T852","span":{"begin":20,"end":30},"obj":"Gene_expression"},{"id":"T853","span":{"begin":20,"end":30},"obj":"Gene_expression"},{"id":"T854","span":{"begin":20,"end":30},"obj":"Gene_expression"},{"id":"T855","span":{"begin":212,"end":221},"obj":"Localization"},{"id":"T856","span":{"begin":212,"end":221},"obj":"Localization"},{"id":"T857","span":{"begin":199,"end":211},"obj":"Regulation"},{"id":"T858","span":{"begin":199,"end":211},"obj":"Regulation"}],"relations":[{"id":"R631","pred":"themeOf","subj":"T841","obj":"T851"},{"id":"R633","pred":"themeOf","subj":"T842","obj":"T852"},{"id":"R635","pred":"themeOf","subj":"T843","obj":"T853"},{"id":"R637","pred":"themeOf","subj":"T844","obj":"T854"},{"id":"R638","pred":"themeOf","subj":"T845","obj":"T855"},{"id":"R639","pred":"themeOf","subj":"T846","obj":"T856"},{"id":"R640","pred":"themeOf","subj":"T855","obj":"T857"},{"id":"R641","pred":"themeOf","subj":"T856","obj":"T858"}],"text":" the Sharpin (SHANK-associated RH domain-interacting protein, other aliases: Rbckl1, Sipl1) gene in mice result in systemic inflammation that is characterized by chronic proliferative dermatitis and dysregulated secretion of T helper1 (Th1) and Th2 cytokines. The cellular and molecular mechanisms underlyi"}

{"project":"bionlp-st-ge-2016-reference","denotations":[{"id":"T73","span":{"begin":5,"end":12},"obj":"Protein"},{"id":"T74","span":{"begin":14,"end":60},"obj":"Protein"},{"id":"T75","span":{"begin":77,"end":83},"obj":"Protein"},{"id":"T76","span":{"begin":85,"end":90},"obj":"Protein"}],"relations":[{"id":"R672","pred":"equivalentTo","subj":"T74","obj":"T73"},{"id":"R674","pred":"equivalentTo","subj":"T76","obj":"T73"},{"id":"R673","pred":"equivalentTo","subj":"T75","obj":"T73"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":" the Sharpin (SHANK-associated RH domain-interacting protein, other aliases: Rbckl1, Sipl1) gene in mice result in systemic inflammation that is characterized by chronic proliferative dermatitis and dysregulated secretion of T helper1 (Th1) and Th2 cytokines. The cellular and molecular mechanisms underlyi"}

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T668","span":{"begin":5,"end":12},"obj":"Q9H0F6"},{"id":"T669","span":{"begin":85,"end":90},"obj":"Q9H0F6"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":" the Sharpin (SHANK-associated RH domain-interacting protein, other aliases: Rbckl1, Sipl1) gene in mice result in systemic inflammation that is characterized by chronic proliferative dermatitis and dysregulated secretion of T helper1 (Th1) and Th2 cytokines. The cellular and molecular mechanisms underlyi"}

{"project":"test2","denotations":[{"id":"T39","span":{"begin":5,"end":12},"obj":"Protein"},{"id":"T40","span":{"begin":14,"end":60},"obj":"Protein"},{"id":"T41","span":{"begin":77,"end":83},"obj":"Protein"},{"id":"T42","span":{"begin":85,"end":90},"obj":"Protein"}],"relations":[{"id":"R663","pred":"equivalentTo","subj":"T40","obj":"T39"},{"id":"R664","pred":"equivalentTo","subj":"T41","obj":"T39"},{"id":"R666","pred":"equivalentTo","subj":"T42","obj":"T39"}],"text":" the Sharpin (SHANK-associated RH domain-interacting protein, other aliases: Rbckl1, Sipl1) gene in mice result in systemic inflammation that is characterized by chronic proliferative dermatitis and dysregulated secretion of T helper1 (Th1) and Th2 cytokines. The cellular and molecular mechanisms underlyi"}