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2_test

Id Subject Object Predicate Lexical cue
22348129-11241277-89575689 138-139 11241277 denotes 5
22348129-11034386-89575690 692-694 11034386 denotes 28
22348129-14978071-89575691 697-699 14978071 denotes 30
22348129-21709223-89575692 991-993 21709223 denotes 31
T76846 138-139 11241277 denotes 5
T94596 692-694 11034386 denotes 28
T64234 697-699 14978071 denotes 30
T67158 991-993 21709223 denotes 31

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T6137 0-10 JJ denotes Th2-biased
T6138 11-25 NN denotes immunogenicity
T6139 26-28 IN denotes of
T6140 29-39 VB denotes stimulated
T6141 40-44 NN denotes cpdm
T6142 45-49 NN denotes BMDC
T6143 50-53 DT denotes The
T6144 54-63 JJ denotes defective
T6145 64-68 NN denotes IL12
T6146 69-79 NN denotes production
T6147 80-81 -LRB- denotes (
T6148 81-85 NN denotes Fig.
T6149 86-88 NN denotes 3A
T6150 88-89 -RRB- denotes )
T6151 90-93 CC denotes and
T6152 94-106 JJ denotes Th2-dominant
T6153 107-115 NN denotes cytokine
T6154 116-123 NN denotes profile
T6155 124-126 IN denotes in
T6156 127-131 NN denotes cpdm
T6157 132-136 NN denotes mice
T6158 137-138 -LRB- denotes [
T6159 138-139 CD denotes 5
T6160 139-140 -RRB- denotes ]
T6161 141-148 VB denotes suggest
T6162 149-153 IN denotes that
T6163 154-157 DT denotes the
T6164 158-165 NN denotes absence
T6165 166-168 IN denotes of
T6166 169-176 NN denotes SHARPIN
T6167 177-184 VB denotes affects
T6168 185-188 DT denotes the
T6169 189-196 NN denotes ability
T6170 197-199 IN denotes of
T6171 200-204 NN denotes cpdm
T6172 205-209 NN denotes BMDC
T6173 210-212 TO denotes to
T6174 213-219 VB denotes induce
T6175 220-221 NN denotes T
T6176 222-226 NN denotes cell
T6177 227-242 NN denotes differentiation
T6178 243-247 IN denotes into
T6179 248-256 NN denotes effector
T6180 257-262 NN denotes cells
T6181 264-274 NN denotes Co-culture
T6182 275-277 IN denotes of
T6183 278-288 JJ denotes allogeneic
T6184 289-294 NN denotes naïve
T6185 295-299 JJ denotes CD4+
T6186 300-301 NN denotes T
T6187 302-307 NN denotes cells
T6188 308-312 IN denotes with
T6189 313-315 NN denotes WT
T6190 316-320 NN denotes BMDC
T6191 321-331 VB denotes stimulated
T6192 332-336 IN denotes with
T6193 337-340 NN denotes LPS
T6194 341-343 CC denotes or
T6195 344-348 NN denotes poly
T6196 349-350 NN denotes I
T6197 350-351 SYM denotes :
T6198 351-352 NN denotes C
T6199 353-361 VB denotes elicited
T6200 362-368 JJ denotes robust
T6201 369-373 NN denotes IFNγ
T6202 374-384 NN denotes production
T6203 384-385 -COMMA- denotes ,
T6204 386-393 IN denotes whereas
T6205 394-397 DT denotes the
T6206 398-411 NN denotes concentration
T6207 412-414 IN denotes of
T6208 415-419 NN denotes IFNγ
T6209 420-422 IN denotes in
T6210 423-427 NN denotes cpdm
T6211 428-434 NN denotes BMDC-T
T6212 435-439 NN denotes cell
T6213 440-448 NN denotes cultures
T6214 449-452 VB denotes was
T6215 453-466 RB denotes significantly
T6216 467-472 JJ denotes lower
T6217 473-478 IN denotes after
T6218 479-482 NN denotes LPS
T6219 483-494 NN denotes stimulation
T6220 495-496 -LRB- denotes (
T6221 496-500 NNP denotes Fig.
T6222 501-503 NN denotes 7A
T6223 503-504 -RRB- denotes )
T6224 504-505 -COMMA- denotes ,
T6225 506-516 VB denotes indicating
T6226 517-525 JJ denotes impaired
T6227 526-540 JJ denotes Th1-polarizing
T6228 541-550 NN denotes abilities
T6229 551-553 IN denotes of
T6230 554-558 NN denotes cpdm
T6231 559-563 NN denotes BMDC
T6232 565-567 IN denotes In
T6233 568-576 NN denotes addition
T6234 577-579 TO denotes to
T6235 580-586 NN denotes TLR3/4
T6236 587-595 NN denotes agonists
T6237 595-596 -COMMA- denotes ,
T6238 597-600 DT denotes the
T6239 601-605 NN denotes TLR2
T6240 606-612 NN denotes ligand
T6241 613-620 NN denotes Pam3CYS
T6242 621-624 VB denotes was
T6243 625-629 VB denotes used
T6244 630-635 IN denotes since
T6245 636-638 PRP denotes it
T6246 639-642 VB denotes has
T6247 643-647 VB denotes been
T6248 648-653 VB denotes shown
T6249 654-656 TO denotes to
T6250 657-663 VB denotes induce
T6251 664-668 CC denotes both
T6252 669-672 NN denotes Th1
T6253 673-676 CC denotes and
T6254 677-680 NN denotes Th2
T6255 681-690 NN denotes responses
T6256 691-692 -LRB- denotes [
T6257 692-694 CD denotes 28
T6258 694-695 -RRB- denotes ]
T6259 695-696 CD denotes –
T6260 696-697 -LRB- denotes [
T6261 697-699 CD denotes 30
T6262 699-700 -RRB- denotes ]
T6263 702-717 JJ denotes Pam3CYS-matured
T6264 718-720 NN denotes WT
T6265 721-725 NN denotes BMDC
T6266 726-733 VB denotes induced
T6267 734-740 JJ denotes robust
T6268 741-745 NN denotes IFNγ
T6269 746-756 NN denotes production
T6270 757-759 IN denotes at
T6271 760-761 DT denotes a
T6272 762-775 RB denotes significantly
T6273 776-782 JJ denotes higher
T6274 783-788 NN denotes level
T6275 789-793 IN denotes than
T6276 794-798 NN denotes cpdm
T6277 799-803 NN denotes BMDC
T6278 804-805 -LRB- denotes (
T6279 805-809 NNP denotes Fig.
T6280 810-812 NN denotes 7A
T6281 812-813 -RRB- denotes )
T6282 815-818 DT denotes The
T6283 819-826 VB denotes reduced
T6284 827-830 NN denotes Th1
T6285 831-846 NN denotes differentiation
T6286 847-856 VB denotes following
T6287 857-864 NN denotes Pam3CYS
T6288 865-876 NN denotes stimulation
T6289 877-879 VB denotes is
T6290 880-890 JJ denotes consistent
T6291 891-895 IN denotes with
T6292 896-899 DT denotes the
T6293 900-906 JJ denotes recent
T6294 907-913 NN denotes report
T6295 914-916 IN denotes of
T6296 917-926 VB denotes decreased
T6297 927-931 NN denotes IL12
T6298 932-942 NN denotes production
T6299 943-945 IN denotes in
T6300 946-950 NN denotes cpdm
T6301 951-962 NN denotes macrophages
T6302 963-972 VB denotes following
T6303 973-977 NN denotes TLR2
T6304 978-989 NN denotes stimulation
T6305 990-991 -LRB- denotes [
T6306 991-993 CD denotes 31
T6307 993-994 -RRB- denotes ]
T6308 996-998 IN denotes In
T6309 999-1007 NN denotes contrast
T6310 1007-1008 -COMMA- denotes ,
T6311 1009-1013 RB denotes more
T6312 1014-1026 JJ denotes Th2-specific
T6313 1027-1030 NN denotes IL4
T6314 1031-1039 NN denotes cytokine
T6315 1040-1043 VB denotes was
T6316 1044-1052 VB denotes produced
T6317 1053-1055 IN denotes in
T6318 1056-1059 DT denotes the
T6319 1060-1064 NN denotes cpdm
T6320 1065-1069 NN denotes BMDC
T6321 1070-1081 NN denotes co-cultures
T6322 1082-1086 IN denotes than
T6323 1087-1090 DT denotes the
T6324 1091-1093 NN denotes WT
T6325 1094-1101 NN denotes control
T6326 1102-1103 -LRB- denotes (
T6327 1103-1107 NNP denotes Fig.
T6328 1108-1110 NN denotes 7B
T6329 1110-1111 -RRB- denotes )
T6330 1111-1112 -COMMA- denotes ,
T6331 1113-1123 VB denotes suggesting
T6332 1124-1134 JJ denotes Th2-skewed
T6333 1135-1149 NN denotes immunogenicity
T6334 1150-1152 IN denotes of
T6335 1153-1157 NN denotes cpdm
T6336 1158-1162 NN denotes BMDC
T6337 1164-1167 DT denotes The
T6338 1168-1178 NN denotes production
T6339 1179-1181 IN denotes of
T6340 1182-1195 JJ denotes Th17-specific
T6341 1196-1204 NN denotes cytokine
T6342 1205-1210 NN denotes IL17A
T6343 1211-1220 VB denotes following
T6344 1221-1224 NN denotes LPS
T6345 1225-1236 NN denotes stimulation
T6346 1237-1239 IN denotes of
T6347 1240-1249 JJ denotes dendritic
T6348 1250-1255 NN denotes cells
T6349 1256-1259 VB denotes was
T6350 1260-1267 JJ denotes similar
T6351 1268-1275 IN denotes between
T6352 1276-1286 VB denotes stimulated
T6353 1287-1289 NN denotes WT
T6354 1290-1293 CC denotes and
T6355 1294-1298 NN denotes cpdm
T6356 1299-1303 NN denotes BMDC
T6357 1304-1314 NN denotes cocultures
T6358 1315-1316 -LRB- denotes (
T6359 1316-1320 NN denotes data
T6360 1321-1324 RB denotes not
T6361 1325-1330 VB denotes shown
T6362 1330-1331 -RRB- denotes )
T6363 1333-1340 IN denotes Despite
T6364 1341-1344 DT denotes the
T6365 1345-1353 JJ denotes distinct
T6366 1354-1358 NN denotes Th1-
T6367 1359-1362 CC denotes and
T6368 1363-1378 JJ denotes Th2-stimulating
T6369 1379-1388 NN denotes abilities
T6370 1389-1391 IN denotes of
T6371 1392-1394 NN denotes WT
T6372 1395-1398 CC denotes and
T6373 1399-1403 NN denotes cpdm
T6374 1404-1408 NN denotes BMDC
T6375 1408-1409 -COMMA- denotes ,
T6376 1410-1414 PRP denotes they
T6377 1415-1419 VB denotes were
T6378 1420-1427 RB denotes equally
T6379 1428-1437 JJ denotes effective
T6380 1438-1440 IN denotes in
T6381 1441-1444 NN denotes IL2
T6382 1445-1455 NN denotes production
T6383 1456-1460 IN denotes from
T6384 1461-1467 NN denotes BMDC-T
T6385 1468-1472 NN denotes cell
T6386 1473-1484 NN denotes co-cultures
T6387 1485-1491 IN denotes except
T6388 1492-1495 IN denotes for
T6389 1496-1500 NN denotes poly
T6390 1501-1502 NN denotes I
T6391 1502-1503 -COLON- denotes :
T6392 1503-1504 NN denotes C
T6393 1505-1516 NN denotes stimulation
T6394 1517-1522 WRB denotes where
T6395 1523-1525 NN denotes WT
T6396 1526-1530 NN denotes BMDC
T6397 1531-1538 VB denotes induced
T6398 1539-1543 JJ denotes more
T6399 1544-1547 NN denotes IL2
T6400 1548-1552 IN denotes than
T6401 1553-1557 NN denotes cpdm
T6402 1558-1562 NN denotes BMDC
T6403 1563-1564 -LRB- denotes (
T6404 1564-1568 NNP denotes Fig.
T6405 1569-1571 NN denotes 7C
T6406 1571-1572 -RRB- denotes )
T6407 1574-1577 DT denotes The
T6408 1578-1588 JJ denotes Th2-biased
T6409 1589-1600 VB denotes stimulating
T6410 1601-1611 NN denotes capability
T6411 1612-1614 IN denotes of
T6412 1615-1619 NN denotes cpdm
T6413 1620-1624 NN denotes BMDC
T6414 1625-1629 WRB denotes when
T6415 1630-1641 VB denotes co-cultured
T6416 1642-1646 IN denotes with
T6417 1647-1657 JJ denotes allogeneic
T6418 1658-1663 NN denotes naïve
T6419 1664-1668 JJ denotes CD4+
T6420 1669-1670 NN denotes T
T6421 1671-1676 NN denotes cells
T6422 1677-1679 VB denotes is
T6423 1680-1690 JJ denotes consistent
T6424 1691-1695 IN denotes with
T6425 1696-1699 DT denotes the
T6426 1700-1712 JJ denotes Th2-dominant
T6427 1713-1721 NN denotes cytokine
T6428 1722-1731 NN denotes phenotype
T6429 1732-1740 VB denotes observed
T6430 1741-1743 IN denotes in
T6431 1744-1748 NN denotes cpdm
T6432 1749-1753 NN denotes mice
T15341 1799-1809 VB denotes Stimulated
T15342 1810-1814 NN denotes cpdm
T15343 1815-1819 NN denotes BMDC
T15344 1820-1827 VB denotes induced
T15345 1828-1838 JJ denotes Th2-biased
T15346 1839-1847 NN denotes cytokine
T15347 1848-1858 NN denotes production
T15348 1859-1863 IN denotes from
T15349 1864-1869 NN denotes naïve
T15350 1870-1874 JJ denotes CD4+
T15351 1875-1876 NN denotes T
T15352 1877-1882 NN denotes cells
T15353 1884-1886 NN denotes WT
T15354 1887-1890 CC denotes and
T15355 1891-1895 NN denotes cpdm
T15356 1896-1900 NN denotes BMDC
T15357 1901-1902 -LRB- denotes (
T15358 1902-1907 CD denotes 5×104
T15359 1908-1913 NN denotes cells
T15360 1914-1916 IN denotes in
T15361 1917-1920 CD denotes 0.1
T15362 1921-1923 NN denotes mL
T15363 1924-1932 JJ denotes complete
T15364 1933-1939 NN denotes medium
T15365 1939-1940 -COLON- denotes ;
T15366 1941-1944 NN denotes MHC
T15367 1945-1954 NN denotes haplotype
T15368 1954-1955 -COLON- denotes :
T15369 1956-1960 NN denotes H-2b
T15370 1960-1961 -RRB- denotes )
T15371 1962-1966 VB denotes were
T15372 1967-1976 VB denotes incubated
T15373 1977-1981 IN denotes with
T15374 1982-1988 NN denotes medium
T15375 1988-1989 -COMMA- denotes ,
T15376 1990-1993 CD denotes 100
T15377 1994-1999 NN denotes ng/mL
T15378 2000-2003 NN denotes LPS
T15379 2003-2004 -COMMA- denotes ,
T15380 2005-2007 CD denotes 25
T15381 2008-2013 NN denotes µg/mL
T15382 2014-2018 NN denotes poly
T15383 2019-2020 NN denotes I
T15384 2020-2021 -COLON- denotes :
T15385 2021-2022 NN denotes C
T15386 2023-2025 CC denotes or
T15387 2026-2027 CD denotes 5
T15388 2028-2033 NN denotes µg/mL
T15389 2034-2041 NN denotes Pam3CYS
T15390 2043-2048 IN denotes After
T15391 2049-2051 CD denotes 24
T15392 2052-2057 NN denotes hours
T15393 2057-2058 -COMMA- denotes ,
T15394 2059-2064 NN denotes cells
T15395 2065-2069 VB denotes were
T15396 2070-2076 VB denotes washed
T15397 2077-2081 IN denotes with
T15398 2082-2085 NNP denotes PBS
T15399 2086-2089 CC denotes and
T15400 2090-2099 VB denotes incubated
T15401 2100-2104 IN denotes with
T15402 2105-2112 RB denotes freshly
T15403 2113-2121 VB denotes isolated
T15404 2122-2132 JJ denotes allogeneic
T15405 2133-2138 NN denotes naïve
T15406 2139-2143 JJ denotes CD4+
T15407 2144-2145 NN denotes T
T15408 2146-2151 NN denotes cells
T15409 2152-2153 -LRB- denotes (
T15410 2153-2160 CD denotes 2.5×105
T15411 2161-2166 NN denotes cells
T15412 2167-2169 IN denotes in
T15413 2170-2173 CD denotes 0.1
T15414 2174-2176 NN denotes mL
T15415 2177-2185 JJ denotes complete
T15416 2186-2192 NN denotes medium
T15417 2192-2193 -COLON- denotes ;
T15418 2194-2197 NN denotes MHC
T15419 2198-2207 NN denotes haplotype
T15420 2207-2208 -COLON- denotes :
T15421 2209-2213 NN denotes H-2d
T15422 2213-2214 -RRB- denotes )
T15423 2216-2221 IN denotes After
T15424 2222-2223 CD denotes 5
T15425 2224-2228 NN denotes days
T15426 2228-2229 -COMMA- denotes ,
T15427 2230-2242 NN denotes supernatants
T15428 2243-2247 VB denotes were
T15429 2248-2257 VB denotes collected
T15430 2258-2261 CC denotes and
T15431 2262-2265 DT denotes the
T15432 2266-2275 NN denotes secretion
T15433 2276-2278 IN denotes of
T15434 2279-2283 NN denotes IFNγ
T15435 2283-2284 -COMMA- denotes ,
T15436 2285-2288 NN denotes IL4
T15437 2288-2289 -COMMA- denotes ,
T15438 2290-2293 CC denotes and
T15439 2294-2297 NN denotes IL2
T15440 2298-2302 VB denotes were
T15441 2303-2311 VB denotes measured
T15442 2312-2314 IN denotes by
T15443 2315-2320 NN denotes ELISA
T15444 2322-2330 JJ denotes Negative
T15445 2331-2339 NN denotes controls
T15446 2340-2343 VB denotes are
T15447 2344-2345 CD denotes 1
T15448 2345-2346 -RRB- denotes )
T15449 2347-2357 VB denotes stimulated
T15450 2358-2362 NN denotes BMDC
T15451 2363-2370 IN denotes without
T15452 2371-2381 NN denotes co-culture
T15453 2382-2386 IN denotes with
T15454 2387-2397 JJ denotes allogeneic
T15455 2398-2402 JJ denotes CD4+
T15456 2403-2404 NN denotes T
T15457 2405-2410 NN denotes cells
T15458 2410-2411 -COLON- denotes ;
T15459 2412-2413 LS denotes 2
T15460 2413-2414 -RRB- denotes )
T15461 2415-2425 JJ denotes allogeneic
T15462 2426-2430 JJ denotes CD4+
T15463 2431-2432 NN denotes T
T15464 2433-2438 NN denotes cells
T15465 2439-2446 IN denotes without
T15466 2447-2457 NN denotes co-culture
T15467 2458-2462 IN denotes with
T15468 2463-2473 VB denotes stimulated
T15469 2474-2478 NN denotes BMDC
T15470 2480-2487 NN denotes Samples
T15471 2488-2492 IN denotes from
T15472 2493-2497 CC denotes both
T15473 2498-2506 JJ denotes negative
T15474 2507-2515 NN denotes controls
T15475 2516-2519 VB denotes had
T15476 2520-2522 DT denotes no
T15477 2523-2533 JJ denotes detectable
T15478 2534-2544 NN denotes production
T15479 2545-2547 IN denotes of
T15480 2548-2551 DT denotes the
T15481 2552-2566 JJ denotes aforementioned
T15482 2567-2576 NN denotes cytokines
T15483 2577-2578 -LRB- denotes (
T15484 2578-2581 RB denotes not
T15485 2582-2587 VB denotes shown
T15486 2587-2588 -RRB- denotes )
T15487 2590-2597 NN denotes Results
T15488 2598-2601 VB denotes are
T15489 2602-2610 VB denotes analyzed
T15490 2611-2616 VB denotes based
T15491 2617-2619 IN denotes on
T15492 2620-2623 CD denotes 2–4
T15493 2624-2628 NN denotes mice
T15494 2629-2632 IN denotes per
T15495 2633-2639 NN denotes group.
T15496 2640-2641 SYM denotes *
T15497 2642-2643 NN denotes P
T15498 2643-2644 SYM denotes <
T15499 2644-2648 CD denotes 0.05
R4958 T6138 T6137 arg1Of immunogenicity,Th2-biased
R4959 T6138 T6139 arg1Of immunogenicity,of
R4960 T6142 T6139 arg2Of BMDC,of
R4961 T6142 T6140 arg2Of BMDC,stimulated
R4962 T6142 T6141 arg1Of BMDC,cpdm
R4963 T6146 T6143 arg1Of production,The
R4964 T6146 T6144 arg1Of production,defective
R4965 T6146 T6145 arg1Of production,IL12
R4966 T6146 T6147 arg1Of production,(
R4967 T6146 T6151 arg1Of production,and
R4968 T6149 T6147 arg2Of 3A,(
R4969 T6149 T6148 arg1Of 3A,Fig.
R4970 T6150 T6147 arg3Of ),(
R4971 T6151 T6161 arg1Of and,suggest
R4972 T6154 T6151 arg2Of profile,and
R4973 T6154 T6152 arg1Of profile,Th2-dominant
R4974 T6154 T6153 arg1Of profile,cytokine
R4975 T6154 T6155 arg1Of profile,in
R4976 T6157 T6155 arg2Of mice,in
R4977 T6157 T6156 arg1Of mice,cpdm
R4978 T6157 T6158 arg1Of mice,[
R4979 T6159 T6158 arg2Of 5,[
R4980 T6160 T6158 arg3Of ],[
R4981 T6164 T6163 arg1Of absence,the
R4982 T6164 T6165 arg1Of absence,of
R4983 T6164 T6167 arg1Of absence,affects
R4984 T6166 T6165 arg2Of SHARPIN,of
R4985 T6167 T6161 arg2Of affects,suggest
R4986 T6167 T6162 arg1Of affects,that
R4987 T6169 T6167 arg2Of ability,affects
R4988 T6169 T6168 arg1Of ability,the
R4989 T6169 T6170 arg1Of ability,of
R4990 T6169 T6173 modOf ability,to
R4991 T6172 T6170 arg2Of BMDC,of
R4992 T6172 T6171 arg1Of BMDC,cpdm
R4993 T6174 T6173 arg1Of induce,to
R4994 T6174 T6178 arg1Of induce,into
R4995 T6177 T6174 arg2Of differentiation,induce
R4996 T6177 T6175 arg1Of differentiation,T
R4997 T6177 T6176 arg1Of differentiation,cell
R4998 T6180 T6178 arg2Of cells,into
R4999 T6180 T6179 arg1Of cells,effector
R5000 T6181 T6182 arg1Of Co-culture,of
R5001 T6181 T6188 arg1Of Co-culture,with
R5002 T6181 T6199 arg1Of Co-culture,elicited
R5003 T6187 T6182 arg2Of cells,of
R5004 T6187 T6183 arg1Of cells,allogeneic
R5005 T6187 T6184 arg1Of cells,naïve
R5006 T6187 T6185 arg1Of cells,CD4+
R5007 T6187 T6186 arg1Of cells,T
R5008 T6190 T6189 arg1Of BMDC,WT
R5009 T6190 T6191 arg2Of BMDC,stimulated
R5010 T6190 T6194 arg1Of BMDC,or
R5011 T6191 T6192 arg1Of stimulated,with
R5012 T6193 T6192 arg2Of LPS,with
R5013 T6194 T6188 arg2Of or,with
R5014 T6198 T6194 arg2Of C,or
R5015 T6198 T6195 arg1Of C,poly
R5016 T6198 T6196 arg1Of C,I
R5017 T6198 T6197 arg1Of C,:
R5018 T6199 T6203 arg1Of elicited,","
R5019 T6199 T6204 arg1Of elicited,whereas
R5020 T6202 T6199 arg2Of production,elicited
R5021 T6202 T6200 arg1Of production,robust
R5022 T6202 T6201 arg1Of production,IFNγ
R5023 T6206 T6205 arg1Of concentration,the
R5024 T6206 T6207 arg1Of concentration,of
R5025 T6206 T6209 arg1Of concentration,in
R5026 T6206 T6214 arg1Of concentration,was
R5027 T6206 T6216 arg1Of concentration,lower
R5028 T6208 T6207 arg2Of IFNγ,of
R5029 T6213 T6209 arg2Of cultures,in
R5030 T6213 T6210 arg1Of cultures,cpdm
R5031 T6213 T6211 arg1Of cultures,BMDC-T
R5032 T6213 T6212 arg1Of cultures,cell
R5033 T6214 T6204 arg2Of was,whereas
R5034 T6214 T6217 arg1Of was,after
R5035 T6214 T6224 arg1Of was,","
R5036 T6214 T6225 modOf was,indicating
R5037 T6216 T6214 arg2Of lower,was
R5038 T6216 T6215 arg1Of lower,significantly
R5039 T6219 T6217 arg2Of stimulation,after
R5040 T6219 T6218 arg1Of stimulation,LPS
R5041 T6219 T6220 arg1Of stimulation,(
R5042 T6222 T6220 arg2Of 7A,(
R5043 T6222 T6221 arg1Of 7A,Fig.
R5044 T6223 T6220 arg3Of ),(
R5045 T6227 T6226 arg1Of Th1-polarizing,impaired
R5046 T6228 T6225 arg2Of abilities,indicating
R5047 T6228 T6227 arg1Of abilities,Th1-polarizing
R5048 T6228 T6229 arg1Of abilities,of
R5049 T6231 T6229 arg2Of BMDC,of
R5050 T6231 T6230 arg1Of BMDC,cpdm
R5051 T6232 T6234 arg1Of In,to
R5052 T6233 T6232 arg2Of addition,In
R5053 T6236 T6232 arg3Of agonists,In
R5054 T6236 T6235 arg1Of agonists,TLR3/4
R5055 T6241 T6238 arg1Of Pam3CYS,the
R5056 T6241 T6239 arg1Of Pam3CYS,TLR2
R5057 T6241 T6240 arg1Of Pam3CYS,ligand
R5058 T6241 T6242 arg1Of Pam3CYS,was
R5059 T6241 T6243 arg2Of Pam3CYS,used
R5060 T6243 T6232 arg1Of used,In
R5061 T6243 T6237 arg1Of used,","
R5062 T6243 T6242 arg2Of used,was
R5063 T6243 T6244 arg1Of used,since
R5064 T6245 T6246 arg1Of it,has
R5065 T6245 T6247 arg1Of it,been
R5066 T6245 T6248 arg2Of it,shown
R5067 T6245 T6250 arg1Of it,induce
R5068 T6248 T6244 arg2Of shown,since
R5069 T6248 T6246 arg2Of shown,has
R5070 T6248 T6247 arg2Of shown,been
R5071 T6250 T6248 arg3Of induce,shown
R5072 T6250 T6249 arg1Of induce,to
R5073 T6250 T6260 arg1Of induce,[
R5074 T6252 T6253 arg1Of Th1,and
R5075 T6254 T6253 arg2Of Th2,and
R5076 T6255 T6250 arg2Of responses,induce
R5077 T6255 T6251 arg1Of responses,both
R5078 T6255 T6252 arg1Of responses,Th1
R5079 T6255 T6254 arg1Of responses,Th2
R5080 T6255 T6256 arg1Of responses,[
R5081 T6255 T6259 arg1Of responses,–
R5082 T6257 T6256 arg2Of 28,[
R5083 T6258 T6256 arg3Of ],[
R5084 T6261 T6260 arg2Of 30,[
R5085 T6262 T6260 arg3Of ],[
R5086 T6265 T6263 arg1Of BMDC,Pam3CYS-matured
R5087 T6265 T6264 arg1Of BMDC,WT
R5088 T6265 T6266 arg1Of BMDC,induced
R5089 T6269 T6266 arg2Of production,induced
R5090 T6269 T6267 arg1Of production,robust
R5091 T6269 T6268 arg1Of production,IFNγ
R5092 T6269 T6270 arg1Of production,at
R5093 T6269 T6275 arg1Of production,than
R5094 T6273 T6272 arg1Of higher,significantly
R5095 T6274 T6270 arg2Of level,at
R5096 T6274 T6271 arg1Of level,a
R5097 T6274 T6273 arg1Of level,higher
R5098 T6277 T6275 arg2Of BMDC,than
R5099 T6277 T6276 arg1Of BMDC,cpdm
R5100 T6277 T6278 arg1Of BMDC,(
R5101 T6280 T6278 arg2Of 7A,(
R5102 T6280 T6279 arg1Of 7A,Fig.
R5103 T6281 T6278 arg3Of ),(
R5104 T6285 T6282 arg1Of differentiation,The
R5105 T6285 T6283 arg2Of differentiation,reduced
R5106 T6285 T6284 arg1Of differentiation,Th1
R5107 T6285 T6286 arg1Of differentiation,following
R5108 T6285 T6289 arg1Of differentiation,is
R5109 T6285 T6290 arg1Of differentiation,consistent
R5110 T6288 T6286 arg2Of stimulation,following
R5111 T6288 T6287 arg1Of stimulation,Pam3CYS
R5112 T6290 T6289 arg2Of consistent,is
R5113 T6290 T6291 arg1Of consistent,with
R5114 T6294 T6291 arg2Of report,with
R5115 T6294 T6292 arg1Of report,the
R5116 T6294 T6293 arg1Of report,recent
R5117 T6294 T6295 arg1Of report,of
R5118 T6294 T6299 arg1Of report,in
R5119 T6298 T6295 arg2Of production,of
R5120 T6298 T6296 arg2Of production,decreased
R5121 T6298 T6297 arg1Of production,IL12
R5122 T6301 T6299 arg2Of macrophages,in
R5123 T6301 T6300 arg1Of macrophages,cpdm
R5124 T6301 T6302 arg1Of macrophages,following
R5125 T6304 T6302 arg2Of stimulation,following
R5126 T6304 T6303 arg1Of stimulation,TLR2
R5127 T6304 T6305 arg1Of stimulation,[
R5128 T6306 T6305 arg2Of 31,[
R5129 T6307 T6305 arg3Of ],[
R5130 T6309 T6308 arg2Of contrast,In
R5131 T6312 T6311 arg1Of Th2-specific,more
R5132 T6314 T6312 arg1Of cytokine,Th2-specific
R5133 T6314 T6313 arg1Of cytokine,IL4
R5134 T6314 T6315 arg1Of cytokine,was
R5135 T6314 T6316 arg2Of cytokine,produced
R5136 T6316 T6308 arg1Of produced,In
R5137 T6316 T6310 arg1Of produced,","
R5138 T6316 T6315 arg2Of produced,was
R5139 T6316 T6317 arg1Of produced,in
R5140 T6316 T6330 arg1Of produced,","
R5141 T6321 T6317 arg2Of co-cultures,in
R5142 T6321 T6318 arg1Of co-cultures,the
R5143 T6321 T6319 arg1Of co-cultures,cpdm
R5144 T6321 T6320 arg1Of co-cultures,BMDC
R5145 T6321 T6322 arg1Of co-cultures,than
R5146 T6325 T6322 arg2Of control,than
R5147 T6325 T6323 arg1Of control,the
R5148 T6325 T6324 arg1Of control,WT
R5149 T6325 T6326 arg1Of control,(
R5150 T6328 T6326 arg2Of 7B,(
R5151 T6328 T6327 arg1Of 7B,Fig.
R5152 T6329 T6326 arg3Of ),(
R5153 T6331 T6316 arg3Of suggesting,produced
R5154 T6333 T6331 arg2Of immunogenicity,suggesting
R5155 T6333 T6332 arg1Of immunogenicity,Th2-skewed
R5156 T6333 T6334 arg1Of immunogenicity,of
R5157 T6336 T6334 arg2Of BMDC,of
R5158 T6336 T6335 arg1Of BMDC,cpdm
R5159 T6338 T6337 arg1Of production,The
R5160 T6338 T6339 arg1Of production,of
R5161 T6338 T6343 arg1Of production,following
R5162 T6338 T6349 arg1Of production,was
R5163 T6338 T6350 arg1Of production,similar
R5164 T6342 T6339 arg2Of IL17A,of
R5165 T6342 T6340 arg1Of IL17A,Th17-specific
R5166 T6342 T6341 arg1Of IL17A,cytokine
R5167 T6345 T6343 arg2Of stimulation,following
R5168 T6345 T6344 arg1Of stimulation,LPS
R5169 T6345 T6346 arg1Of stimulation,of
R5170 T6348 T6346 arg2Of cells,of
R5171 T6348 T6347 arg1Of cells,dendritic
R5172 T6349 T6351 arg1Of was,between
R5173 T6350 T6349 arg2Of similar,was
R5174 T6353 T6352 arg2Of WT,stimulated
R5175 T6353 T6354 arg1Of WT,and
R5176 T6354 T6351 arg2Of and,between
R5177 T6357 T6354 arg2Of cocultures,and
R5178 T6357 T6355 arg1Of cocultures,cpdm
R5179 T6357 T6356 arg1Of cocultures,BMDC
R5180 T6357 T6358 arg1Of cocultures,(
R5181 T6359 T6358 arg2Of data,(
R5182 T6359 T6361 arg2Of data,shown
R5183 T6361 T6360 arg1Of shown,not
R5184 T6362 T6358 arg3Of ),(
R5185 T6365 T6366 arg1Of distinct,Th1-
R5186 T6365 T6367 arg1Of distinct,and
R5187 T6368 T6367 arg2Of Th2-stimulating,and
R5188 T6369 T6363 arg2Of abilities,Despite
R5189 T6369 T6364 arg1Of abilities,the
R5190 T6369 T6365 arg1Of abilities,distinct
R5191 T6369 T6368 arg1Of abilities,Th2-stimulating
R5192 T6369 T6370 arg1Of abilities,of
R5193 T6371 T6372 arg1Of WT,and
R5194 T6373 T6372 arg2Of cpdm,and
R5195 T6374 T6370 arg2Of BMDC,of
R5196 T6374 T6371 arg1Of BMDC,WT
R5197 T6374 T6373 arg1Of BMDC,cpdm
R5198 T6376 T6377 arg1Of they,were
R5199 T6376 T6379 arg1Of they,effective
R5200 T6377 T6363 arg1Of were,Despite
R5201 T6377 T6375 arg1Of were,","
R5202 T6379 T6377 arg2Of effective,were
R5203 T6379 T6378 arg1Of effective,equally
R5204 T6379 T6380 arg1Of effective,in
R5205 T6382 T6380 arg2Of production,in
R5206 T6382 T6381 arg1Of production,IL2
R5207 T6382 T6383 arg1Of production,from
R5208 T6382 T6388 arg1Of production,for
R5209 T6382 T6394 arg1Of production,where
R5210 T6386 T6383 arg2Of co-cultures,from
R5211 T6386 T6384 arg1Of co-cultures,BMDC-T
R5212 T6386 T6385 arg1Of co-cultures,cell
R5213 T6388 T6387 arg1Of for,except
R5214 T6390 T6391 arg1Of I,:
R5215 T6392 T6391 arg2Of C,:
R5216 T6393 T6388 arg2Of stimulation,for
R5217 T6393 T6389 arg1Of stimulation,poly
R5218 T6393 T6390 arg1Of stimulation,I
R5219 T6393 T6392 arg1Of stimulation,C
R5220 T6396 T6395 arg1Of BMDC,WT
R5221 T6396 T6397 arg1Of BMDC,induced
R5222 T6397 T6394 arg2Of induced,where
R5223 T6399 T6397 arg2Of IL2,induced
R5224 T6399 T6398 arg1Of IL2,more
R5225 T6399 T6400 arg1Of IL2,than
R5226 T6402 T6400 arg2Of BMDC,than
R5227 T6402 T6401 arg1Of BMDC,cpdm
R5228 T6402 T6403 arg1Of BMDC,(
R5229 T6405 T6403 arg2Of 7C,(
R5230 T6405 T6404 arg1Of 7C,Fig.
R5231 T6406 T6403 arg3Of ),(
R5232 T6410 T6407 arg1Of capability,The
R5233 T6410 T6408 arg1Of capability,Th2-biased
R5234 T6410 T6409 arg1Of capability,stimulating
R5235 T6410 T6411 arg1Of capability,of
R5236 T6410 T6415 arg1Of capability,co-cultured
R5237 T6410 T6422 arg1Of capability,is
R5238 T6410 T6423 arg1Of capability,consistent
R5239 T6413 T6411 arg2Of BMDC,of
R5240 T6413 T6412 arg1Of BMDC,cpdm
R5241 T6415 T6414 arg2Of co-cultured,when
R5242 T6415 T6416 arg1Of co-cultured,with
R5243 T6421 T6416 arg2Of cells,with
R5244 T6421 T6417 arg1Of cells,allogeneic
R5245 T6421 T6418 arg1Of cells,naïve
R5246 T6421 T6419 arg1Of cells,CD4+
R5247 T6421 T6420 arg1Of cells,T
R5248 T6422 T6414 arg1Of is,when
R5249 T6423 T6422 arg2Of consistent,is
R5250 T6423 T6424 arg1Of consistent,with
R5251 T6428 T6424 arg2Of phenotype,with
R5252 T6428 T6425 arg1Of phenotype,the
R5253 T6428 T6426 arg1Of phenotype,Th2-dominant
R5254 T6428 T6427 arg1Of phenotype,cytokine
R5255 T6428 T6429 arg2Of phenotype,observed
R5256 T6429 T6430 arg1Of observed,in
R5257 T6432 T6430 arg2Of mice,in
R5258 T6432 T6431 arg1Of mice,cpdm
R12806 T15343 T15341 arg2Of BMDC,Stimulated
R12807 T15343 T15342 arg1Of BMDC,cpdm
R12808 T15343 T15344 arg1Of BMDC,induced
R12809 T15347 T15344 arg2Of production,induced
R12810 T15347 T15345 arg1Of production,Th2-biased
R12811 T15347 T15346 arg1Of production,cytokine
R12812 T15347 T15348 arg1Of production,from
R12813 T15352 T15348 arg2Of cells,from
R12814 T15352 T15349 arg1Of cells,naïve
R12815 T15352 T15350 arg1Of cells,CD4+
R12816 T15352 T15351 arg1Of cells,T
R12817 T15353 T15354 arg1Of WT,and
R12818 T15355 T15354 arg2Of cpdm,and
R12819 T15356 T15353 arg1Of BMDC,WT
R12820 T15356 T15355 arg1Of BMDC,cpdm
R12821 T15356 T15357 arg1Of BMDC,(
R12822 T15356 T15371 arg1Of BMDC,were
R12823 T15356 T15372 arg2Of BMDC,incubated
R12824 T15359 T15357 arg2Of cells,(
R12825 T15359 T15358 arg1Of cells,5×104
R12826 T15359 T15360 arg1Of cells,in
R12827 T15359 T15368 arg1Of cells,:
R12828 T15364 T15361 arg1Of medium,0.1
R12829 T15364 T15362 arg1Of medium,mL
R12830 T15364 T15363 arg1Of medium,complete
R12831 T15364 T15365 arg1Of medium,;
R12832 T15365 T15360 arg2Of ;,in
R12833 T15367 T15365 arg2Of haplotype,;
R12834 T15367 T15366 arg1Of haplotype,MHC
R12835 T15369 T15368 arg2Of H-2b,:
R12836 T15370 T15357 arg3Of ),(
R12837 T15372 T15371 arg2Of incubated,were
R12838 T15372 T15373 arg1Of incubated,with
R12839 T15374 T15375 arg1Of medium,","
R12840 T15375 T15379 arg1Of ",",","
R12841 T15378 T15375 arg2Of LPS,","
R12842 T15378 T15376 arg1Of LPS,100
R12843 T15378 T15377 arg1Of LPS,ng/mL
R12844 T15379 T15386 arg1Of ",",or
R12845 T15383 T15382 arg1Of I,poly
R12846 T15383 T15384 arg1Of I,:
R12847 T15385 T15379 arg2Of C,","
R12848 T15385 T15380 arg1Of C,25
R12849 T15385 T15381 arg1Of C,µg/mL
R12850 T15385 T15383 arg1Of C,I
R12851 T15386 T15373 arg2Of or,with
R12852 T15389 T15386 arg2Of Pam3CYS,or
R12853 T15389 T15387 arg1Of Pam3CYS,5
R12854 T15389 T15388 arg1Of Pam3CYS,µg/mL
R12855 T15392 T15390 arg2Of hours,After
R12856 T15392 T15391 arg1Of hours,24
R12857 T15394 T15395 arg1Of cells,were
R12858 T15394 T15396 arg2Of cells,washed
R12859 T15394 T15400 arg2Of cells,incubated
R12860 T15396 T15397 arg1Of washed,with
R12861 T15396 T15399 arg1Of washed,and
R12862 T15398 T15397 arg2Of PBS,with
R12863 T15399 T15390 arg1Of and,After
R12864 T15399 T15393 arg1Of and,","
R12865 T15399 T15395 arg2Of and,were
R12866 T15400 T15399 arg2Of incubated,and
R12867 T15400 T15401 arg1Of incubated,with
R12868 T15403 T15402 arg1Of isolated,freshly
R12869 T15408 T15401 arg2Of cells,with
R12870 T15408 T15403 arg1Of cells,isolated
R12871 T15408 T15404 arg1Of cells,allogeneic
R12872 T15408 T15405 arg1Of cells,naïve
R12873 T15408 T15406 arg1Of cells,CD4+
R12874 T15408 T15407 arg1Of cells,T
R12875 T15408 T15409 arg1Of cells,(
R12876 T15411 T15409 arg2Of cells,(
R12877 T15411 T15410 arg1Of cells,2.5×105
R12878 T15411 T15412 arg1Of cells,in
R12879 T15411 T15420 arg1Of cells,:
R12880 T15416 T15413 arg1Of medium,0.1
R12881 T15416 T15414 arg1Of medium,mL
R12882 T15416 T15415 arg1Of medium,complete
R12883 T15416 T15417 arg1Of medium,;
R12884 T15417 T15412 arg2Of ;,in
R12885 T15419 T15417 arg2Of haplotype,;
R12886 T15419 T15418 arg1Of haplotype,MHC
R12887 T15421 T15420 arg2Of H-2d,:
R12888 T15422 T15409 arg3Of ),(
R12889 T15425 T15423 arg2Of days,After
R12890 T15425 T15424 arg1Of days,5
R12891 T15427 T15428 arg1Of supernatants,were
R12892 T15427 T15429 arg2Of supernatants,collected
R12893 T15429 T15428 arg2Of collected,were
R12894 T15429 T15430 arg1Of collected,and
R12895 T15430 T15423 arg1Of and,After
R12896 T15430 T15426 arg1Of and,","
R12897 T15432 T15431 arg1Of secretion,the
R12898 T15432 T15433 arg1Of secretion,of
R12899 T15432 T15440 arg1Of secretion,were
R12900 T15432 T15441 arg2Of secretion,measured
R12901 T15434 T15435 arg1Of IFNγ,","
R12902 T15435 T15438 arg1Of ",",and
R12903 T15436 T15435 arg2Of IL4,","
R12904 T15438 T15433 arg2Of and,of
R12905 T15438 T15437 arg1Of and,","
R12906 T15439 T15438 arg2Of IL2,and
R12907 T15441 T15430 arg2Of measured,and
R12908 T15441 T15440 arg2Of measured,were
R12909 T15443 T15441 arg1Of ELISA,measured
R12910 T15443 T15442 arg2Of ELISA,by
R12911 T15445 T15444 arg1Of controls,Negative
R12912 T15445 T15446 arg1Of controls,are
R12913 T15447 T15449 arg1Of 1,stimulated
R12914 T15449 T15446 arg2Of stimulated,are
R12915 T15449 T15448 arg1Of stimulated,)
R12916 T15449 T15451 arg1Of stimulated,without
R12917 T15450 T15449 arg2Of BMDC,stimulated
R12918 T15452 T15451 arg2Of co-culture,without
R12919 T15452 T15453 arg1Of co-culture,with
R12920 T15457 T15454 arg1Of cells,allogeneic
R12921 T15457 T15455 arg1Of cells,CD4+
R12922 T15457 T15456 arg1Of cells,T
R12923 T15457 T15458 arg1Of cells,;
R12924 T15458 T15453 arg2Of ;,with
R12925 T15459 T15460 arg1Of 2,)
R12926 T15464 T15458 arg2Of cells,;
R12927 T15464 T15459 arg1Of cells,2
R12928 T15464 T15461 arg1Of cells,allogeneic
R12929 T15464 T15462 arg1Of cells,CD4+
R12930 T15464 T15463 arg1Of cells,T
R12931 T15464 T15465 arg1Of cells,without
R12932 T15466 T15465 arg2Of co-culture,without
R12933 T15466 T15467 arg1Of co-culture,with
R12934 T15469 T15467 arg2Of BMDC,with
R12935 T15469 T15468 arg2Of BMDC,stimulated
R12936 T15470 T15471 arg1Of Samples,from
R12937 T15470 T15475 arg1Of Samples,had
R12938 T15474 T15471 arg2Of controls,from
R12939 T15474 T15472 arg1Of controls,both
R12940 T15474 T15473 arg1Of controls,negative
R12941 T15478 T15475 arg2Of production,had
R12942 T15478 T15476 arg1Of production,no
R12943 T15478 T15477 arg1Of production,detectable
R12944 T15478 T15479 arg1Of production,of
R12945 T15482 T15479 arg2Of cytokines,of
R12946 T15482 T15480 arg1Of cytokines,the
R12947 T15482 T15481 arg1Of cytokines,aforementioned
R12948 T15482 T15483 arg1Of cytokines,(
R12949 T15485 T15483 arg2Of shown,(
R12950 T15485 T15484 arg1Of shown,not
R12951 T15486 T15483 arg3Of ),(
R12952 T15487 T15488 arg1Of Results,are
R12953 T15487 T15489 arg2Of Results,analyzed
R12954 T15489 T15488 arg2Of analyzed,are
R12955 T15489 T15490 arg1Of analyzed,based
R12956 T15491 T15490 arg2Of on,based
R12957 T15493 T15491 arg2Of mice,on
R12958 T15493 T15492 arg1Of mice,2–4
R12959 T15493 T15494 arg1Of mice,per
R12960 T15495 T15494 arg2Of group.,per
R12961 T15499 T15489 arg3Of 0.05,analyzed
R12962 T15499 T15496 arg1Of 0.05,*
R12963 T15499 T15497 arg1Of 0.05,P
R12964 T15499 T15498 arg1Of 0.05,<

bionlp-st-ge-2016-coref

Id Subject Object Predicate Lexical cue
T15500 2548-2576 Anaphor denotes the aforementioned cytokines
T15501 2279-2283 Antecedent denotes IFNγ
T15502 2285-2288 Antecedent denotes IL4
T15503 2294-2297 Antecedent denotes IL2
R12965 T15500 T15501 boundBy the aforementioned cytokines,IFNγ
R12966 T15500 T15502 boundBy the aforementioned cytokines,IL4
R12967 T15500 T15503 boundBy the aforementioned cytokines,IL2

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T5830 0-10 JJ denotes Th2-biased
T5831 11-25 NN denotes immunogenicity
T5832 26-28 IN denotes of
T5833 29-39 VBN denotes stimulated
T5834 40-44 NN denotes cpdm
T5835 45-49 NNP denotes BMDC
T5836 50-53 NNP denotes The
T5837 54-63 JJ denotes defective
T5838 64-68 NN denotes IL12
T5839 69-79 NN denotes production
T5840 80-81 -LRB- denotes (
T5841 81-85 NNP denotes Fig.
T5842 86-88 NNP denotes 3A
T5843 88-89 -RRB- denotes )
T5844 90-93 CC denotes and
T5845 94-106 JJ denotes Th2-dominant
T5846 107-115 NN denotes cytokine
T5847 116-123 NN denotes profile
T5848 124-126 IN denotes in
T5849 127-131 NN denotes cpdm
T5850 132-136 NNS denotes mice
T5851 137-138 VBP denotes [
T5852 138-139 CD denotes 5
T5853 139-140 JJ denotes ]
T5854 141-148 VBP denotes suggest
T5855 149-153 IN denotes that
T5856 154-157 DT denotes the
T5857 158-165 NN denotes absence
T5858 166-168 IN denotes of
T5859 169-176 NNP denotes SHARPIN
T5860 177-184 VBZ denotes affects
T5861 185-188 DT denotes the
T5862 189-196 NN denotes ability
T5863 197-199 IN denotes of
T5864 200-204 NN denotes cpdm
T5865 205-209 NNP denotes BMDC
T5866 210-212 TO denotes to
T5867 213-219 VB denotes induce
T5868 220-221 NNP denotes T
T5869 222-226 NN denotes cell
T5870 227-242 NN denotes differentiation
T5871 243-247 IN denotes into
T5872 248-256 NN denotes effector
T5873 257-262 NNS denotes cells
T5874 262-263 . denotes .
T5875 264-274 NN denotes Co-culture
T5876 275-277 IN denotes of
T5877 278-288 JJ denotes allogeneic
T5878 289-294 NN denotes naïve
T5879 295-298 NNP denotes CD4
T5880 298-299 NNP denotes +
T5881 300-301 NNP denotes T
T5882 302-307 NNS denotes cells
T5883 308-312 IN denotes with
T5884 313-315 NNP denotes WT
T5885 316-320 NNP denotes BMDC
T5886 321-331 VBD denotes stimulated
T5887 332-336 IN denotes with
T5888 337-340 NNP denotes LPS
T5889 341-343 CC denotes or
T5890 344-348 RB denotes poly
T5891 349-350 PRP denotes I
T5892 350-351 : denotes :
T5893 351-352 NNP denotes C
T5894 353-361 VBD denotes elicited
T5895 362-368 JJ denotes robust
T5896 369-373 JJ denotes IFNγ
T5897 374-384 NN denotes production
T5898 384-385 , denotes ,
T5899 386-393 IN denotes whereas
T5900 394-397 DT denotes the
T5901 398-411 NN denotes concentration
T5902 412-414 IN denotes of
T5903 415-419 NNP denotes IFNγ
T5904 420-422 IN denotes in
T5905 423-427 NN denotes cpdm
T5906 428-434 NNP denotes BMDC-T
T5907 435-439 NN denotes cell
T5908 440-448 NNS denotes cultures
T5909 449-452 VBD denotes was
T5910 453-466 RB denotes significantly
T5911 467-472 JJR denotes lower
T5912 473-478 IN denotes after
T5913 479-482 NNP denotes LPS
T5914 483-494 NN denotes stimulation
T5915 495-496 -LRB- denotes (
T5916 496-500 NNP denotes Fig.
T5917 501-503 NN denotes 7A
T5918 503-504 -RRB- denotes )
T5919 504-505 , denotes ,
T5920 506-516 VBG denotes indicating
T5921 517-525 VBN denotes impaired
T5922 526-540 JJ denotes Th1-polarizing
T5923 541-550 NNS denotes abilities
T5924 551-553 IN denotes of
T5925 554-558 NN denotes cpdm
T5926 559-563 NNP denotes BMDC
T5927 563-564 . denotes .
T5928 565-567 IN denotes In
T5929 568-576 NN denotes addition
T5930 577-579 TO denotes to
T5931 580-586 CD denotes TLR3/4
T5932 587-595 NNS denotes agonists
T5933 595-596 , denotes ,
T5934 597-600 DT denotes the
T5935 601-605 CD denotes TLR2
T5936 606-612 NN denotes ligand
T5937 613-620 NNS denotes Pam3CYS
T5938 621-624 VBD denotes was
T5939 625-629 VBN denotes used
T5940 630-635 IN denotes since
T5941 636-638 PRP denotes it
T5942 639-642 VBZ denotes has
T5943 643-647 VBN denotes been
T5944 648-653 VBN denotes shown
T5945 654-656 TO denotes to
T5946 657-663 VB denotes induce
T5947 664-668 DT denotes both
T5948 669-672 CD denotes Th1
T5949 673-676 CC denotes and
T5950 677-680 CD denotes Th2
T5951 681-690 NNS denotes responses
T5952 691-692 NNP denotes [
T5953 692-694 CD denotes 28
T5954 694-695 NNP denotes ]
T5955 696-697 NNP denotes [
T5956 697-699 CD denotes 30
T5957 699-700 NNP denotes ]
T5958 700-701 . denotes .
T5959 702-717 JJ denotes Pam3CYS-matured
T5960 718-720 NNP denotes WT
T5961 721-725 NNP denotes BMDC
T5962 726-733 VBD denotes induced
T5963 734-740 JJ denotes robust
T5964 741-745 JJ denotes IFNγ
T5965 746-756 NN denotes production
T5966 757-759 IN denotes at
T5967 760-761 DT denotes a
T5968 762-775 RB denotes significantly
T5969 776-782 JJR denotes higher
T5970 783-788 NN denotes level
T5971 789-793 IN denotes than
T5972 794-798 NN denotes cpdm
T5973 799-803 NNP denotes BMDC
T5974 804-805 -LRB- denotes (
T5975 805-809 NNP denotes Fig.
T5976 810-812 NN denotes 7A
T5977 812-813 -RRB- denotes )
T5978 813-814 . denotes .
T5979 815-818 DT denotes The
T5980 819-826 JJ denotes reduced
T5981 827-830 JJ denotes Th1
T5982 831-846 NN denotes differentiation
T5983 847-856 VBG denotes following
T5984 857-864 NNP denotes Pam3CYS
T5985 865-876 NN denotes stimulation
T5986 877-879 VBZ denotes is
T5987 880-890 JJ denotes consistent
T5988 891-895 IN denotes with
T5989 896-899 DT denotes the
T5990 900-906 JJ denotes recent
T5991 907-913 NN denotes report
T5992 914-916 IN denotes of
T5993 917-926 VBN denotes decreased
T5994 927-931 NN denotes IL12
T5995 932-942 NN denotes production
T5996 943-945 IN denotes in
T5997 946-950 NN denotes cpdm
T5998 951-962 NNS denotes macrophages
T5999 963-972 VBG denotes following
T6000 973-977 CD denotes TLR2
T6001 978-989 NN denotes stimulation
T6002 990-991 NNP denotes [
T6003 991-993 CD denotes 31
T6004 993-994 NNP denotes ]
T6005 994-995 . denotes .
T6006 996-998 IN denotes In
T6007 999-1007 NN denotes contrast
T6008 1007-1008 , denotes ,
T6009 1009-1013 JJR denotes more
T6010 1014-1026 JJ denotes Th2-specific
T6011 1027-1030 NN denotes IL4
T6012 1031-1039 NN denotes cytokine
T6013 1040-1043 VBD denotes was
T6014 1044-1052 VBN denotes produced
T6015 1053-1055 IN denotes in
T6016 1056-1059 DT denotes the
T6017 1060-1064 NN denotes cpdm
T6018 1065-1069 NNP denotes BMDC
T6019 1070-1081 NNS denotes co-cultures
T6020 1082-1086 IN denotes than
T6021 1087-1090 DT denotes the
T6022 1091-1093 NNP denotes WT
T6023 1094-1101 NN denotes control
T6024 1102-1103 -LRB- denotes (
T6025 1103-1107 NNP denotes Fig.
T6026 1108-1110 NN denotes 7B
T6027 1110-1111 -RRB- denotes )
T6028 1111-1112 , denotes ,
T6029 1113-1123 VBG denotes suggesting
T6030 1124-1134 JJ denotes Th2-skewed
T6031 1135-1149 NN denotes immunogenicity
T6032 1150-1152 IN denotes of
T6033 1153-1157 NN denotes cpdm
T6034 1158-1162 NNP denotes BMDC
T6035 1162-1163 . denotes .
T6036 1164-1167 DT denotes The
T6037 1168-1178 NN denotes production
T6038 1179-1181 IN denotes of
T6039 1182-1195 JJ denotes Th17-specific
T6040 1196-1204 NN denotes cytokine
T6041 1205-1210 NNP denotes IL17A
T6042 1211-1220 VBG denotes following
T6043 1221-1224 NNP denotes LPS
T6044 1225-1236 NN denotes stimulation
T6045 1237-1239 IN denotes of
T6046 1240-1249 JJ denotes dendritic
T6047 1250-1255 NNS denotes cells
T6048 1256-1259 VBD denotes was
T6049 1260-1267 JJ denotes similar
T6050 1268-1275 IN denotes between
T6051 1276-1286 VBN denotes stimulated
T6052 1287-1289 NNP denotes WT
T6053 1290-1293 CC denotes and
T6054 1294-1298 VB denotes cpdm
T6055 1299-1303 NNP denotes BMDC
T6056 1304-1314 NNS denotes cocultures
T6057 1315-1316 -LRB- denotes (
T6058 1316-1320 NNS denotes data
T6059 1321-1324 RB denotes not
T6060 1325-1330 VBN denotes shown
T6061 1330-1331 -RRB- denotes )
T6062 1331-1332 . denotes .
T6063 1333-1340 IN denotes Despite
T6064 1341-1344 DT denotes the
T6065 1345-1353 JJ denotes distinct
T6066 1354-1357 SYM denotes Th1
T6067 1357-1358 : denotes -
T6068 1359-1362 CC denotes and
T6069 1363-1378 JJ denotes Th2-stimulating
T6070 1379-1388 NNS denotes abilities
T6071 1389-1391 IN denotes of
T6072 1392-1394 NNP denotes WT
T6073 1395-1398 CC denotes and
T6074 1399-1403 VB denotes cpdm
T6075 1404-1408 NNP denotes BMDC
T6076 1408-1409 , denotes ,
T6077 1410-1414 PRP denotes they
T6078 1415-1419 VBD denotes were
T6079 1420-1427 RB denotes equally
T6080 1428-1437 JJ denotes effective
T6081 1438-1440 IN denotes in
T6082 1441-1444 JJ denotes IL2
T6083 1445-1455 NN denotes production
T6084 1456-1460 IN denotes from
T6085 1461-1467 NNP denotes BMDC-T
T6086 1468-1472 NN denotes cell
T6087 1473-1484 NNS denotes co-cultures
T6088 1485-1491 IN denotes except
T6089 1492-1495 IN denotes for
T6090 1496-1500 NN denotes poly
T6091 1501-1502 PRP denotes I
T6092 1502-1503 : denotes :
T6093 1503-1504 NNP denotes C
T6094 1505-1516 NN denotes stimulation
T6095 1517-1522 WRB denotes where
T6096 1523-1525 NNP denotes WT
T6097 1526-1530 NNP denotes BMDC
T6098 1531-1538 VBD denotes induced
T6099 1539-1543 RBR denotes more
T6100 1544-1547 JJ denotes IL2
T6101 1548-1552 IN denotes than
T6102 1553-1557 NN denotes cpdm
T6103 1558-1562 NNP denotes BMDC
T6104 1563-1564 -LRB- denotes (
T6105 1564-1568 NNP denotes Fig.
T6106 1569-1571 NNP denotes 7C
T6107 1571-1572 -RRB- denotes )
T6108 1572-1573 . denotes .
T6109 1574-1577 DT denotes The
T6110 1578-1588 JJ denotes Th2-biased
T6111 1589-1600 VBG denotes stimulating
T6112 1601-1611 NN denotes capability
T6113 1612-1614 IN denotes of
T6114 1615-1619 NN denotes cpdm
T6115 1620-1624 NNP denotes BMDC
T6116 1625-1629 WRB denotes when
T6117 1630-1641 JJ denotes co-cultured
T6118 1642-1646 IN denotes with
T6119 1647-1657 JJ denotes allogeneic
T6120 1658-1663 NN denotes naïve
T6121 1664-1667 NNP denotes CD4
T6122 1667-1668 NNP denotes +
T6123 1669-1670 NNP denotes T
T6124 1671-1676 NNS denotes cells
T6125 1677-1679 VBZ denotes is
T6126 1680-1690 JJ denotes consistent
T6127 1691-1695 IN denotes with
T6128 1696-1699 DT denotes the
T6129 1700-1712 JJ denotes Th2-dominant
T6130 1713-1721 NN denotes cytokine
T6131 1722-1731 NN denotes phenotype
T6132 1732-1740 VBD denotes observed
T6133 1741-1743 IN denotes in
T6134 1744-1748 NN denotes cpdm
T6135 1749-1753 NNS denotes mice
T6136 1753-1754 . denotes .
T15510 1799-1809 VBN denotes Stimulated
T15511 1810-1814 NN denotes cpdm
T15512 1815-1819 NNP denotes BMDC
T15513 1820-1827 VBD denotes induced
T15514 1828-1838 JJ denotes Th2-biased
T15515 1839-1847 NN denotes cytokine
T15516 1848-1858 NN denotes production
T15517 1859-1863 IN denotes from
T15518 1864-1869 NN denotes naïve
T15519 1870-1873 NNP denotes CD4
T15520 1873-1874 NNP denotes +
T15521 1875-1876 NNP denotes T
T15522 1877-1882 NNS denotes cells
T15523 1882-1883 . denotes .
T15524 1884-1886 NNP denotes WT
T15525 1887-1890 CC denotes and
T15526 1891-1895 VB denotes cpdm
T15527 1896-1900 NNP denotes BMDC
T15528 1901-1902 -LRB- denotes (
T15529 1902-1903 CD denotes 5
T15530 1903-1904 CD denotes ×
T15531 1904-1907 CD denotes 104
T15532 1908-1913 NNS denotes cells
T15533 1914-1916 IN denotes in
T15534 1917-1920 CD denotes 0.1
T15535 1921-1923 NNP denotes mL
T15536 1924-1932 JJ denotes complete
T15537 1933-1939 NN denotes medium
T15538 1939-1940 : denotes ;
T15539 1941-1944 NNP denotes MHC
T15540 1945-1954 NN denotes haplotype
T15541 1954-1955 : denotes :
T15542 1956-1960 NN denotes H-2b
T15543 1960-1961 -RRB- denotes )
T15544 1962-1966 VBD denotes were
T15545 1967-1976 VBN denotes incubated
T15546 1977-1981 IN denotes with
T15547 1982-1988 NN denotes medium
T15548 1988-1989 , denotes ,
T15549 1990-1993 CD denotes 100
T15550 1994-1999 NNP denotes ng/mL
T15551 2000-2003 NNP denotes LPS
T15552 2003-2004 , denotes ,
T15553 2005-2007 CD denotes 25
T15554 2008-2010 NN denotes µg
T15555 2010-2011 CD denotes /
T15556 2011-2013 NNP denotes mL
T15557 2014-2018 NN denotes poly
T15558 2019-2020 PRP denotes I
T15559 2020-2021 : denotes :
T15560 2021-2022 NNP denotes C
T15561 2023-2025 CC denotes or
T15562 2026-2027 CD denotes 5
T15563 2028-2030 NN denotes µg
T15564 2030-2031 NN denotes /
T15565 2031-2033 NNP denotes mL
T15566 2034-2041 NNP denotes Pam3CYS
T15567 2041-2042 . denotes .
T15568 2043-2048 IN denotes After
T15569 2049-2051 CD denotes 24
T15570 2052-2057 NNS denotes hours
T15571 2057-2058 , denotes ,
T15572 2059-2064 NNS denotes cells
T15573 2065-2069 VBD denotes were
T15574 2070-2076 VBN denotes washed
T15575 2077-2081 IN denotes with
T15576 2082-2085 NNP denotes PBS
T15577 2086-2089 CC denotes and
T15578 2090-2099 VBN denotes incubated
T15579 2100-2104 IN denotes with
T15580 2105-2112 RB denotes freshly
T15581 2113-2121 VBN denotes isolated
T15582 2122-2132 JJ denotes allogeneic
T15583 2133-2138 NN denotes naïve
T15584 2139-2142 NNP denotes CD4
T15585 2142-2143 NNP denotes +
T15586 2144-2145 NNP denotes T
T15587 2146-2151 NNS denotes cells
T15588 2152-2153 -LRB- denotes (
T15589 2153-2156 CD denotes 2.5
T15590 2156-2157 CD denotes ×
T15591 2157-2160 CD denotes 105
T15592 2161-2166 NNS denotes cells
T15593 2167-2169 IN denotes in
T15594 2170-2173 CD denotes 0.1
T15595 2174-2176 NNP denotes mL
T15596 2177-2185 JJ denotes complete
T15597 2186-2192 NN denotes medium
T15598 2192-2193 : denotes ;
T15599 2194-2197 NNP denotes MHC
T15600 2198-2207 NN denotes haplotype
T15601 2207-2208 : denotes :
T15602 2209-2213 NN denotes H-2d
T15603 2213-2214 -RRB- denotes )
T15616 2279-2283 NNP denotes IFNγ
T15617 2283-2284 , denotes ,
T15618 2285-2288 NNP denotes IL4
T15619 2288-2289 , denotes ,
T15620 2290-2293 CC denotes and
T15621 2294-2297 NNP denotes IL2
T15622 2298-2302 VBD denotes were
T15623 2303-2311 VBN denotes measured
T15624 2312-2314 IN denotes by
T15625 2315-2320 NNP denotes ELISA
T15626 2320-2321 . denotes .
T15627 2322-2330 JJ denotes Negative
T15628 2331-2339 NNS denotes controls
T15629 2340-2343 VBP denotes are
T15630 2344-2345 CD denotes 1
T15631 2345-2346 -RRB- denotes )
T15632 2347-2357 VBD denotes stimulated
T15633 2358-2362 NNP denotes BMDC
T15634 2363-2370 IN denotes without
T15635 2371-2381 NN denotes co-culture
T15636 2382-2386 IN denotes with
T15637 2387-2397 JJ denotes allogeneic
T15638 2398-2401 NNP denotes CD4
T15639 2401-2402 CD denotes +
T15640 2403-2404 NNP denotes T
T15641 2405-2410 NNS denotes cells
T15642 2410-2411 : denotes ;
T15643 2412-2413 LS denotes 2
T15644 2413-2414 -RRB- denotes )
T15645 2415-2425 JJ denotes allogeneic
T15646 2426-2429 NNP denotes CD4
T15647 2429-2430 CD denotes +
T15648 2431-2432 NNP denotes T
T15649 2433-2438 NNS denotes cells
T15650 2439-2446 IN denotes without
T15651 2447-2457 NN denotes co-culture
T15652 2458-2462 IN denotes with
T15653 2463-2473 VBN denotes stimulated
T15654 2474-2478 NNP denotes BMDC
T15655 2478-2479 . denotes .
T15656 2480-2487 NNS denotes Samples
T15657 2488-2492 IN denotes from
T15658 2493-2497 DT denotes both
T15659 2498-2506 JJ denotes negative
T15660 2507-2515 NNS denotes controls
T15661 2516-2519 VBD denotes had
T15662 2520-2522 DT denotes no
T15663 2523-2533 JJ denotes detectable
T15664 2534-2544 NN denotes production
T15665 2545-2547 IN denotes of
T15666 2548-2551 DT denotes the
T15667 2552-2566 JJ denotes aforementioned
T15668 2567-2576 NNS denotes cytokines
T15669 2577-2578 -LRB- denotes (
T15670 2578-2581 RB denotes not
T15671 2582-2587 VBN denotes shown
T15672 2587-2588 -RRB- denotes )
T15673 2588-2589 . denotes .
T15674 2590-2597 NNS denotes Results
T15675 2598-2601 VBP denotes are
T15676 2602-2610 VBN denotes analyzed
T15677 2611-2616 VBN denotes based
T15678 2617-2619 IN denotes on
T15679 2620-2621 CD denotes 2
T15680 2622-2623 CD denotes 4
T15681 2624-2628 NNS denotes mice
T15682 2629-2632 IN denotes per
T15683 2633-2638 NN denotes group
T15684 2638-2639 . denotes .
T15685 2640-2641 SYM denotes *
T15686 2642-2643 NN denotes P
T15687 2643-2644 NN denotes <
T15688 2644-2648 CD denotes 0.05
T15689 2648-2649 . denotes .
T15604 2214-2215 . denotes .
T15605 2216-2221 IN denotes After
T15606 2222-2223 CD denotes 5
T15607 2224-2228 NNS denotes days
T15608 2228-2229 , denotes ,
T15609 2230-2242 NNS denotes supernatants
T15610 2243-2247 VBD denotes were
T15611 2248-2257 VBN denotes collected
T15612 2258-2261 CC denotes and
T15613 2262-2265 DT denotes the
T15614 2266-2275 NN denotes secretion
T15615 2276-2278 IN denotes of
R4651 T5830 T5831 amod Th2-biased,immunogenicity
R4652 T5831 T5854 nsubj immunogenicity,suggest
R4653 T5832 T5831 prep of,immunogenicity
R4654 T5833 T5834 amod stimulated,cpdm
R4655 T5834 T5832 pobj cpdm,of
R4656 T5835 T5839 nmod BMDC,production
R4657 T5836 T5839 det The,production
R4658 T5837 T5839 amod defective,production
R4659 T5838 T5839 compound IL12,production
R4660 T5839 T5847 nmod production,profile
R4661 T5840 T5839 punct (,production
R4662 T5841 T5842 compound Fig.,3A
R4663 T5842 T5839 appos 3A,production
R4664 T5843 T5839 punct ),production
R4665 T5844 T5839 cc and,production
R4666 T5845 T5847 amod Th2-dominant,profile
R4667 T5846 T5847 compound cytokine,profile
R4668 T5847 T5831 conj profile,immunogenicity
R4669 T5848 T5847 prep in,profile
R4670 T5849 T5850 compound cpdm,mice
R4671 T5850 T5848 pobj mice,in
R4672 T5851 T5854 amod [,suggest
R4673 T5852 T5853 nummod 5,]
R4674 T5853 T5854 nsubj ],suggest
R4675 T5854 T5854 ROOT suggest,suggest
R4676 T5855 T5860 mark that,affects
R4677 T5856 T5857 det the,absence
R4678 T5857 T5860 nsubj absence,affects
R4679 T5858 T5857 prep of,absence
R4680 T5859 T5858 pobj SHARPIN,of
R4681 T5860 T5854 ccomp affects,suggest
R4682 T5861 T5862 det the,ability
R4683 T5862 T5860 dobj ability,affects
R4684 T5863 T5862 prep of,ability
R4685 T5864 T5865 compound cpdm,BMDC
R4686 T5865 T5863 pobj BMDC,of
R4687 T5866 T5867 aux to,induce
R4688 T5867 T5862 acl induce,ability
R4689 T5868 T5870 compound T,differentiation
R4690 T5869 T5870 compound cell,differentiation
R4691 T5870 T5867 dobj differentiation,induce
R4692 T5871 T5867 prep into,induce
R4693 T5872 T5873 amod effector,cells
R4694 T5873 T5871 pobj cells,into
R4695 T5874 T5854 punct .,suggest
R4696 T5875 T5886 nsubj Co-culture,stimulated
R4697 T5876 T5875 prep of,Co-culture
R4698 T5877 T5878 amod allogeneic,naïve
R4699 T5878 T5882 compound naïve,cells
R4700 T5879 T5882 compound CD4,cells
R4701 T5880 T5882 compound +,cells
R4702 T5881 T5882 compound T,cells
R4703 T5882 T5876 pobj cells,of
R4704 T5883 T5875 prep with,Co-culture
R4705 T5884 T5885 compound WT,BMDC
R4706 T5885 T5883 pobj BMDC,with
R4707 T5886 T5886 ROOT stimulated,stimulated
R4708 T5887 T5886 prep with,stimulated
R4709 T5888 T5887 pobj LPS,with
R4710 T5889 T5886 cc or,stimulated
R4711 T5890 T5894 advmod poly,elicited
R4712 T5891 T5894 nsubj I,elicited
R4713 T5892 T5894 punct :,elicited
R4714 T5893 T5894 nsubj C,elicited
R4715 T5894 T5886 conj elicited,stimulated
R4716 T5895 T5897 amod robust,production
R4717 T5896 T5897 compound IFNγ,production
R4718 T5897 T5894 dobj production,elicited
R4719 T5898 T5894 punct ",",elicited
R4720 T5899 T5909 mark whereas,was
R4721 T5900 T5901 det the,concentration
R4722 T5901 T5909 nsubj concentration,was
R4723 T5902 T5901 prep of,concentration
R4724 T5903 T5902 pobj IFNγ,of
R4725 T5904 T5901 prep in,concentration
R4726 T5905 T5906 compound cpdm,BMDC-T
R4727 T5906 T5908 compound BMDC-T,cultures
R4728 T5907 T5908 compound cell,cultures
R4729 T5908 T5904 pobj cultures,in
R4730 T5909 T5894 advcl was,elicited
R4731 T5910 T5911 advmod significantly,lower
R4732 T5911 T5909 acomp lower,was
R4733 T5912 T5909 prep after,was
R4734 T5913 T5914 compound LPS,stimulation
R4735 T5914 T5912 pobj stimulation,after
R4736 T5915 T5914 punct (,stimulation
R4737 T5916 T5917 compound Fig.,7A
R4738 T5917 T5914 appos 7A,stimulation
R4739 T5918 T5914 punct ),stimulation
R4740 T5919 T5909 punct ",",was
R4741 T5920 T5909 advcl indicating,was
R4742 T5921 T5923 amod impaired,abilities
R4743 T5922 T5923 amod Th1-polarizing,abilities
R4744 T5923 T5920 dobj abilities,indicating
R4745 T5924 T5923 prep of,abilities
R4746 T5925 T5926 compound cpdm,BMDC
R4747 T5926 T5924 pobj BMDC,of
R4748 T5927 T5894 punct .,elicited
R4749 T5928 T5939 prep In,used
R4750 T5929 T5928 pobj addition,In
R4751 T5930 T5929 prep to,addition
R4752 T5931 T5932 nummod TLR3/4,agonists
R4753 T5932 T5930 pobj agonists,to
R4754 T5933 T5932 punct ",",agonists
R4755 T5934 T5937 det the,Pam3CYS
R4756 T5935 T5937 nummod TLR2,Pam3CYS
R4757 T5936 T5937 compound ligand,Pam3CYS
R4758 T5937 T5939 nsubjpass Pam3CYS,used
R4759 T5938 T5939 auxpass was,used
R4760 T5939 T5939 ROOT used,used
R4761 T5940 T5944 mark since,shown
R4762 T5941 T5944 nsubjpass it,shown
R4763 T5942 T5944 aux has,shown
R4764 T5943 T5944 auxpass been,shown
R4765 T5944 T5939 advcl shown,used
R4766 T5945 T5946 aux to,induce
R4767 T5946 T5944 xcomp induce,shown
R4768 T5947 T5948 det both,Th1
R4769 T5948 T5946 dobj Th1,induce
R4770 T5949 T5948 cc and,Th1
R4771 T5950 T5948 conj Th2,Th1
R4772 T5951 T5939 nsubjpass responses,used
R4773 T5952 T5954 compound [,]
R4774 T5953 T5954 compound 28,]
R4775 T5954 T5951 nsubj ],responses
R4776 T5955 T5957 nmod [,]
R4777 T5956 T5957 nummod 30,]
R4778 T5957 T5954 appos ],]
R4779 T5958 T5939 punct .,used
R4780 T5959 T5961 compound Pam3CYS-matured,BMDC
R4781 T5960 T5961 compound WT,BMDC
R4782 T5961 T5962 nsubj BMDC,induced
R4783 T5962 T5962 ROOT induced,induced
R4784 T5963 T5965 amod robust,production
R4785 T5964 T5965 compound IFNγ,production
R4786 T5965 T5962 dobj production,induced
R4787 T5966 T5962 prep at,induced
R4788 T5967 T5970 det a,level
R4789 T5968 T5969 advmod significantly,higher
R4790 T5969 T5970 amod higher,level
R4791 T5970 T5966 pobj level,at
R4792 T5971 T5962 prep than,induced
R4793 T5972 T5973 compound cpdm,BMDC
R4794 T5973 T5971 pobj BMDC,than
R4795 T5974 T5976 punct (,7A
R4796 T5975 T5976 compound Fig.,7A
R4797 T5976 T5973 appos 7A,BMDC
R4798 T5977 T5976 punct ),7A
R4799 T5978 T5962 punct .,induced
R4800 T5979 T5982 det The,differentiation
R4801 T5980 T5982 amod reduced,differentiation
R4802 T5981 T5982 compound Th1,differentiation
R4803 T5982 T5986 nsubj differentiation,is
R4804 T5983 T5982 prep following,differentiation
R4805 T5984 T5985 compound Pam3CYS,stimulation
R4806 T5985 T5983 pobj stimulation,following
R4807 T5986 T5986 ROOT is,is
R4808 T5987 T5986 acomp consistent,is
R4809 T5988 T5987 prep with,consistent
R4810 T5989 T5991 det the,report
R4811 T5990 T5991 amod recent,report
R4812 T5991 T5988 pobj report,with
R4813 T5992 T5991 prep of,report
R4814 T5993 T5995 amod decreased,production
R4815 T5994 T5995 compound IL12,production
R4816 T5995 T5992 pobj production,of
R4817 T5996 T5995 prep in,production
R4818 T5997 T5998 compound cpdm,macrophages
R4819 T5998 T5996 pobj macrophages,in
R4820 T5999 T5991 prep following,report
R4821 T6000 T6001 compound TLR2,stimulation
R4822 T6001 T5999 pobj stimulation,following
R4823 T6002 T6004 nmod [,]
R4824 T6003 T6004 nummod 31,]
R4825 T6004 T6001 appos ],stimulation
R4826 T6005 T5986 punct .,is
R4827 T6006 T6014 prep In,produced
R4828 T6007 T6006 pobj contrast,In
R4829 T6008 T6014 punct ",",produced
R4830 T6009 T6012 amod more,cytokine
R4831 T6010 T6012 amod Th2-specific,cytokine
R4832 T6011 T6012 compound IL4,cytokine
R4833 T6012 T6014 nsubjpass cytokine,produced
R4834 T6013 T6014 auxpass was,produced
R4835 T6014 T6014 ROOT produced,produced
R4836 T6015 T6014 prep in,produced
R4837 T6016 T6019 det the,co-cultures
R4838 T6017 T6019 compound cpdm,co-cultures
R4839 T6018 T6019 compound BMDC,co-cultures
R4840 T6019 T6015 pobj co-cultures,in
R4841 T6020 T6014 prep than,produced
R4842 T6021 T6023 det the,control
R4843 T6022 T6023 compound WT,control
R4844 T6023 T6020 pobj control,than
R4845 T6024 T6023 punct (,control
R4846 T6025 T6026 compound Fig.,7B
R4847 T6026 T6023 appos 7B,control
R4848 T6027 T6023 punct ),control
R4849 T6028 T6014 punct ",",produced
R4850 T6029 T6014 advcl suggesting,produced
R4851 T6030 T6031 amod Th2-skewed,immunogenicity
R4852 T6031 T6029 dobj immunogenicity,suggesting
R4853 T6032 T6031 prep of,immunogenicity
R4854 T6033 T6034 compound cpdm,BMDC
R4855 T6034 T6032 pobj BMDC,of
R4856 T6035 T6014 punct .,produced
R4857 T6036 T6037 det The,production
R4858 T6037 T6048 nsubj production,was
R4859 T6038 T6037 prep of,production
R4860 T6039 T6041 amod Th17-specific,IL17A
R4861 T6040 T6041 compound cytokine,IL17A
R4862 T6041 T6038 pobj IL17A,of
R4863 T6042 T6037 prep following,production
R4864 T6043 T6044 compound LPS,stimulation
R4865 T6044 T6042 pobj stimulation,following
R4866 T6045 T6044 prep of,stimulation
R4867 T6046 T6047 amod dendritic,cells
R4868 T6047 T6045 pobj cells,of
R4869 T6048 T6048 ROOT was,was
R4870 T6049 T6048 acomp similar,was
R4871 T6050 T6049 prep between,similar
R4872 T6051 T6052 amod stimulated,WT
R4873 T6052 T6050 pobj WT,between
R4874 T6053 T6052 cc and,WT
R4875 T6054 T6055 compound cpdm,BMDC
R4876 T6055 T6052 conj BMDC,WT
R4877 T6056 T6052 conj cocultures,WT
R4878 T6057 T6056 punct (,cocultures
R4879 T6058 T6061 nmod data,)
R4880 T6059 T6060 neg not,shown
R4881 T6060 T6058 acl shown,data
R4882 T6061 T6056 punct ),cocultures
R4883 T6062 T6048 punct .,was
R4884 T6063 T6078 prep Despite,were
R4885 T6064 T6070 det the,abilities
R4886 T6065 T6070 amod distinct,abilities
R4887 T6066 T6070 punct Th1,abilities
R4888 T6067 T6066 punct -,Th1
R4889 T6068 T6066 cc and,Th1
R4890 T6069 T6070 amod Th2-stimulating,abilities
R4891 T6070 T6063 pobj abilities,Despite
R4892 T6071 T6070 prep of,abilities
R4893 T6072 T6071 pobj WT,of
R4894 T6073 T6070 cc and,abilities
R4895 T6074 T6075 compound cpdm,BMDC
R4896 T6075 T6070 conj BMDC,abilities
R4897 T6076 T6078 punct ",",were
R4898 T6077 T6078 nsubj they,were
R4899 T6078 T6078 ROOT were,were
R4900 T6079 T6080 advmod equally,effective
R4901 T6080 T6078 acomp effective,were
R4902 T6081 T6080 prep in,effective
R4903 T6082 T6083 amod IL2,production
R4905 T6084 T6083 prep from,production
R4906 T6085 T6087 compound BMDC-T,co-cultures
R4907 T6086 T6087 compound cell,co-cultures
R4908 T6087 T6084 pobj co-cultures,from
R4909 T6088 T6083 prep except,production
R4910 T6089 T6088 prep for,except
R4911 T6090 T6089 pobj poly,for
R4912 T6091 T6078 nsubj I,were
R4913 T6092 T6091 punct :,I
R4914 T6093 T6094 compound C,stimulation
R4915 T6094 T6091 appos stimulation,I
R4916 T6095 T6098 advmod where,induced
R4917 T6096 T6097 compound WT,BMDC
R4918 T6097 T6098 nsubj BMDC,induced
R4919 T6098 T6094 relcl induced,stimulation
R4920 T6099 T6100 advmod more,IL2
R4921 T6100 T6098 dobj IL2,induced
R4922 T6101 T6100 prep than,IL2
R4923 T6102 T6103 compound cpdm,BMDC
R4924 T6103 T6101 pobj BMDC,than
R4925 T6104 T6103 punct (,BMDC
R4926 T6105 T6106 compound Fig.,7C
R4927 T6106 T6103 appos 7C,BMDC
R4928 T6107 T6103 punct ),BMDC
R4929 T6108 T6078 punct .,were
R4930 T6109 T6112 det The,capability
R4931 T6110 T6112 amod Th2-biased,capability
R4932 T6111 T6112 amod stimulating,capability
R4933 T6112 T6125 nsubj capability,is
R4934 T6113 T6112 prep of,capability
R4935 T6114 T6115 compound cpdm,BMDC
R4936 T6115 T6113 pobj BMDC,of
R4937 T6116 T6117 advmod when,co-cultured
R4938 T6117 T6125 nsubj co-cultured,is
R4939 T6118 T6117 prep with,co-cultured
R4940 T6119 T6120 amod allogeneic,naïve
R4941 T6120 T6124 compound naïve,cells
R4942 T6121 T6124 compound CD4,cells
R4943 T6122 T6124 compound +,cells
R4944 T6123 T6124 compound T,cells
R4945 T6124 T6118 pobj cells,with
R4946 T6125 T6125 ROOT is,is
R4947 T6126 T6125 acomp consistent,is
R4948 T6127 T6126 prep with,consistent
R4949 T6128 T6131 det the,phenotype
R4950 T6129 T6131 amod Th2-dominant,phenotype
R4951 T6130 T6131 compound cytokine,phenotype
R4952 T6131 T6127 pobj phenotype,with
R4953 T6132 T6125 advcl observed,is
R4954 T6133 T6132 prep in,observed
R4955 T6134 T6135 compound cpdm,mice
R4956 T6135 T6133 pobj mice,in
R4957 T6136 T6125 punct .,is
R12968 T15510 T15513 advcl Stimulated,induced
R12969 T15511 T15512 compound cpdm,BMDC
R12970 T15512 T15513 nsubj BMDC,induced
R12971 T15513 T15513 ROOT induced,induced
R12972 T15514 T15516 amod Th2-biased,production
R12973 T15515 T15516 compound cytokine,production
R12974 T15516 T15513 dobj production,induced
R12975 T15517 T15516 prep from,production
R12976 T15518 T15522 amod naïve,cells
R12977 T15519 T15522 compound CD4,cells
R12978 T15520 T15522 compound +,cells
R12979 T15521 T15522 compound T,cells
R12980 T15522 T15517 pobj cells,from
R12981 T15523 T15513 punct .,induced
R12982 T15524 T15532 nmod WT,cells
R12983 T15525 T15524 cc and,WT
R12984 T15526 T15527 compound cpdm,BMDC
R12985 T15527 T15524 conj BMDC,WT
R12986 T15528 T15529 punct (,5
R12987 T15529 T15532 nummod 5,cells
R12988 T15530 T15532 nummod ×,cells
R12989 T15531 T15532 nummod 104,cells
R12990 T15532 T15532 ROOT cells,cells
R12991 T15533 T15532 prep in,cells
R12992 T15534 T15537 nummod 0.1,medium
R12993 T15535 T15537 nmod mL,medium
R12994 T15536 T15537 amod complete,medium
R12995 T15537 T15533 pobj medium,in
R12996 T15538 T15532 punct ;,cells
R12997 T15539 T15532 appos MHC,cells
R12998 T15540 T15545 nsubjpass haplotype,incubated
R12999 T15541 T15540 punct :,haplotype
R13000 T15542 T15540 appos H-2b,haplotype
R13001 T15543 T15540 punct ),haplotype
R13002 T15544 T15545 auxpass were,incubated
R13003 T15545 T15545 ROOT incubated,incubated
R13004 T15546 T15545 prep with,incubated
R13005 T15547 T15546 pobj medium,with
R13006 T15548 T15547 punct ",",medium
R13007 T15549 T15551 nummod 100,LPS
R13008 T15550 T15551 compound ng/mL,LPS
R13009 T15551 T15547 conj LPS,medium
R13010 T15552 T15551 punct ",",LPS
R13011 T15553 T15555 quantmod 25,/
R13012 T15554 T15555 quantmod µg,/
R13013 T15555 T15557 npadvmod /,poly
R13014 T15556 T15557 compound mL,poly
R13015 T15557 T15558 dep poly,I
R13016 T15558 T15545 advcl I,incubated
R13017 T15559 T15558 punct :,I
R13018 T15560 T15558 appos C,I
R13019 T15561 T15560 cc or,C
R13020 T15562 T15564 nummod 5,/
R13021 T15563 T15564 compound µg,/
R13022 T15564 T15566 compound /,Pam3CYS
R13023 T15565 T15566 compound mL,Pam3CYS
R13024 T15566 T15560 conj Pam3CYS,C
R13025 T15567 T15545 punct .,incubated
R13026 T15568 T15574 prep After,washed
R13027 T15569 T15570 nummod 24,hours
R13028 T15570 T15568 pobj hours,After
R13029 T15571 T15574 punct ",",washed
R13030 T15572 T15574 nsubjpass cells,washed
R13031 T15573 T15574 auxpass were,washed
R13032 T15574 T15574 ROOT washed,washed
R13033 T15575 T15574 prep with,washed
R13034 T15576 T15575 pobj PBS,with
R13035 T15577 T15574 cc and,washed
R13036 T15578 T15574 conj incubated,washed
R13037 T15579 T15578 prep with,incubated
R13038 T15580 T15581 advmod freshly,isolated
R13039 T15581 T15583 amod isolated,naïve
R13040 T15582 T15583 amod allogeneic,naïve
R13041 T15583 T15587 compound naïve,cells
R13042 T15584 T15587 compound CD4,cells
R13043 T15585 T15587 compound +,cells
R13044 T15586 T15587 compound T,cells
R13045 T15587 T15579 pobj cells,with
R13046 T15588 T15587 punct (,cells
R13047 T15589 T15592 nummod 2.5,cells
R13048 T15590 T15592 nummod ×,cells
R13049 T15591 T15592 nummod 105,cells
R13050 T15592 T15587 appos cells,cells
R13051 T15593 T15592 prep in,cells
R13052 T15594 T15597 nummod 0.1,medium
R13053 T15595 T15597 nmod mL,medium
R13054 T15596 T15597 amod complete,medium
R13055 T15597 T15593 pobj medium,in
R13056 T15598 T15587 punct ;,cells
R13057 T15599 T15600 compound MHC,haplotype
R13058 T15600 T15578 conj haplotype,incubated
R13059 T15601 T15600 punct :,haplotype
R13060 T15602 T15600 appos H-2d,haplotype
R13061 T15603 T15600 punct ),haplotype
R13062 T15604 T15574 punct .,washed
R13063 T15605 T15611 prep After,collected
R13064 T15606 T15607 nummod 5,days
R13065 T15607 T15605 pobj days,After
R13066 T15608 T15611 punct ",",collected
R13067 T15609 T15611 nsubjpass supernatants,collected
R13068 T15610 T15611 auxpass were,collected
R13069 T15611 T15611 ROOT collected,collected
R13070 T15612 T15611 cc and,collected
R13071 T15613 T15614 det the,secretion
R13072 T15614 T15623 nsubjpass secretion,measured
R13073 T15615 T15614 prep of,secretion
R13074 T15616 T15615 pobj IFNγ,of
R13075 T15617 T15616 punct ",",IFNγ
R13076 T15618 T15616 conj IL4,IFNγ
R13077 T15619 T15618 punct ",",IL4
R13078 T15620 T15618 cc and,IL4
R13079 T15621 T15618 conj IL2,IL4
R13080 T15622 T15623 auxpass were,measured
R13081 T15623 T15611 conj measured,collected
R13082 T15624 T15623 agent by,measured
R13083 T15625 T15624 pobj ELISA,by
R13084 T15626 T15623 punct .,measured
R13085 T15627 T15628 amod Negative,controls
R13086 T15628 T15629 nsubj controls,are
R13087 T15629 T15653 ccomp are,stimulated
R13088 T15630 T15629 attr 1,are
R13089 T15631 T15630 punct ),1
R13090 T15632 T15629 conj stimulated,are
R13091 T15633 T15632 dobj BMDC,stimulated
R13092 T15634 T15632 prep without,stimulated
R13093 T15635 T15634 pobj co-culture,without
R13094 T15636 T15632 prep with,stimulated
R13095 T15637 T15641 amod allogeneic,cells
R13096 T15638 T15641 compound CD4,cells
R13097 T15639 T15641 nummod +,cells
R13098 T15640 T15641 compound T,cells
R13099 T15641 T15636 pobj cells,with
R13100 T15642 T15653 punct ;,stimulated
R13101 T15643 T15649 meta 2,cells
R13102 T15644 T15643 punct ),2
R13103 T15645 T15649 amod allogeneic,cells
R13104 T15646 T15649 compound CD4,cells
R13105 T15647 T15649 nummod +,cells
R13106 T15648 T15649 compound T,cells
R13107 T15649 T15653 nsubj cells,stimulated
R13108 T15650 T15649 prep without,cells
R13109 T15651 T15650 pobj co-culture,without
R13110 T15652 T15649 prep with,cells
R13111 T15653 T15653 ROOT stimulated,stimulated
R13112 T15654 T15653 dobj BMDC,stimulated
R13113 T15655 T15653 punct .,stimulated
R13114 T15656 T15661 nsubj Samples,had
R13115 T15657 T15656 prep from,Samples
R13116 T15658 T15660 det both,controls
R13117 T15659 T15660 amod negative,controls
R13118 T15660 T15657 pobj controls,from
R13119 T15661 T15661 ROOT had,had
R13120 T15662 T15664 det no,production
R13121 T15663 T15664 amod detectable,production
R13122 T15664 T15661 dobj production,had
R13123 T15665 T15664 prep of,production
R13124 T15666 T15668 det the,cytokines
R13142 T15684 T15676 punct .,analyzed
R13143 T15685 T15687 punct *,<
R13144 T15686 T15687 compound P,<
R13145 T15687 T15688 compound <,0.05
R13146 T15688 T15688 ROOT 0.05,0.05
R13147 T15689 T15688 punct .,0.05
R4904 T6083 T6081 pobj production,in
R13125 T15667 T15668 amod aforementioned,cytokines
R13126 T15668 T15665 pobj cytokines,of
R13127 T15669 T15671 punct (,shown
R13128 T15670 T15671 neg not,shown
R13129 T15671 T15664 parataxis shown,production
R13130 T15672 T15664 punct ),production
R13131 T15673 T15661 punct .,had
R13132 T15674 T15676 nsubjpass Results,analyzed
R13133 T15675 T15676 auxpass are,analyzed
R13134 T15676 T15676 ROOT analyzed,analyzed
R13135 T15677 T15676 prep based,analyzed
R13136 T15678 T15677 prep on,based
R13137 T15679 T15678 pobj 2,on
R13138 T15680 T15681 nummod 4,mice
R13139 T15681 T15679 appos mice,2
R13140 T15682 T15681 prep per,mice
R13141 T15683 T15682 pobj group,per

GO-BP

Id Subject Object Predicate Lexical cue
T6453 222-242 http://purl.obolibrary.org/obo/GO_0030154 denotes cell differentiation
T6454 1466-1475 http://purl.obolibrary.org/obo/GO_0031295 denotes T cell co
T15697 1839-1858 http://purl.obolibrary.org/obo/GO_0001816 denotes cytokine production
T15698 2266-2275 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion

GO-MF

Id Subject Object Predicate Lexical cue
T6455 606-612 http://purl.obolibrary.org/obo/GO_0005488 denotes ligand

GO-CC

Id Subject Object Predicate Lexical cue
T6456 222-226 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T6457 435-439 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T6458 1468-1472 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T6459 1671-1676 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T15699 1877-1882 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T15700 1908-1913 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T15701 2059-2064 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T15702 2146-2151 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T15703 2161-2166 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T15704 2405-2410 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T15705 2433-2438 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

sentences

Id Subject Object Predicate Lexical cue
T5820 0-49 Sentence denotes Th2-biased immunogenicity of stimulated cpdm BMDC
T5821 50-263 Sentence denotes The defective IL12 production (Fig. 3A) and Th2-dominant cytokine profile in cpdm mice [5] suggest that the absence of SHARPIN affects the ability of cpdm BMDC to induce T cell differentiation into effector cells.
T5822 264-564 Sentence denotes Co-culture of allogeneic naïve CD4+ T cells with WT BMDC stimulated with LPS or poly I:C elicited robust IFNγ production, whereas the concentration of IFNγ in cpdm BMDC-T cell cultures was significantly lower after LPS stimulation (Fig. 7A), indicating impaired Th1-polarizing abilities of cpdm BMDC.
T5823 565-701 Sentence denotes In addition to TLR3/4 agonists, the TLR2 ligand Pam3CYS was used since it has been shown to induce both Th1 and Th2 responses [28]–[30].
T5824 702-814 Sentence denotes Pam3CYS-matured WT BMDC induced robust IFNγ production at a significantly higher level than cpdm BMDC (Fig. 7A).
T5825 815-995 Sentence denotes The reduced Th1 differentiation following Pam3CYS stimulation is consistent with the recent report of decreased IL12 production in cpdm macrophages following TLR2 stimulation [31].
T5826 996-1163 Sentence denotes In contrast, more Th2-specific IL4 cytokine was produced in the cpdm BMDC co-cultures than the WT control (Fig. 7B), suggesting Th2-skewed immunogenicity of cpdm BMDC.
T5827 1164-1332 Sentence denotes The production of Th17-specific cytokine IL17A following LPS stimulation of dendritic cells was similar between stimulated WT and cpdm BMDC cocultures (data not shown).
T5828 1333-1573 Sentence denotes Despite the distinct Th1- and Th2-stimulating abilities of WT and cpdm BMDC, they were equally effective in IL2 production from BMDC-T cell co-cultures except for poly I:C stimulation where WT BMDC induced more IL2 than cpdm BMDC (Fig. 7C).
T5829 1574-1754 Sentence denotes The Th2-biased stimulating capability of cpdm BMDC when co-cultured with allogeneic naïve CD4+ T cells is consistent with the Th2-dominant cytokine phenotype observed in cpdm mice.
T15334 1799-1883 Sentence denotes Stimulated cpdm BMDC induced Th2-biased cytokine production from naïve CD4+ T cells.
T15335 1884-2042 Sentence denotes WT and cpdm BMDC (5×104 cells in 0.1 mL complete medium; MHC haplotype: H-2b) were incubated with medium, 100 ng/mL LPS, 25 µg/mL poly I:C or 5 µg/mL Pam3CYS.
T15336 2043-2215 Sentence denotes After 24 hours, cells were washed with PBS and incubated with freshly isolated allogeneic naïve CD4+ T cells (2.5×105 cells in 0.1 mL complete medium; MHC haplotype: H-2d).
T15337 2216-2321 Sentence denotes After 5 days, supernatants were collected and the secretion of IFNγ, IL4, and IL2 were measured by ELISA.
T15338 2322-2479 Sentence denotes Negative controls are 1) stimulated BMDC without co-culture with allogeneic CD4+ T cells; 2) allogeneic CD4+ T cells without co-culture with stimulated BMDC.
T15339 2480-2589 Sentence denotes Samples from both negative controls had no detectable production of the aforementioned cytokines (not shown).
T15340 2590-2649 Sentence denotes Results are analyzed based on 2–4 mice per group. * P<0.05.
T113 0-49 Sentence denotes Th2-biased immunogenicity of stimulated cpdm BMDC
T114 50-263 Sentence denotes The defective IL12 production (Fig. 3A) and Th2-dominant cytokine profile in cpdm mice [5] suggest that the absence of SHARPIN affects the ability of cpdm BMDC to induce T cell differentiation into effector cells.
T115 264-564 Sentence denotes Co-culture of allogeneic naïve CD4+ T cells with WT BMDC stimulated with LPS or poly I:C elicited robust IFNγ production, whereas the concentration of IFNγ in cpdm BMDC-T cell cultures was significantly lower after LPS stimulation (Fig. 7A), indicating impaired Th1-polarizing abilities of cpdm BMDC.
T116 565-701 Sentence denotes In addition to TLR3/4 agonists, the TLR2 ligand Pam3CYS was used since it has been shown to induce both Th1 and Th2 responses [28]–[30].
T117 702-814 Sentence denotes Pam3CYS-matured WT BMDC induced robust IFNγ production at a significantly higher level than cpdm BMDC (Fig. 7A).
T118 815-995 Sentence denotes The reduced Th1 differentiation following Pam3CYS stimulation is consistent with the recent report of decreased IL12 production in cpdm macrophages following TLR2 stimulation [31].
T119 996-1163 Sentence denotes In contrast, more Th2-specific IL4 cytokine was produced in the cpdm BMDC co-cultures than the WT control (Fig. 7B), suggesting Th2-skewed immunogenicity of cpdm BMDC.
T120 1164-1332 Sentence denotes The production of Th17-specific cytokine IL17A following LPS stimulation of dendritic cells was similar between stimulated WT and cpdm BMDC cocultures (data not shown).
T121 1333-1573 Sentence denotes Despite the distinct Th1- and Th2-stimulating abilities of WT and cpdm BMDC, they were equally effective in IL2 production from BMDC-T cell co-cultures except for poly I:C stimulation where WT BMDC induced more IL2 than cpdm BMDC (Fig. 7C).
T122 1574-1754 Sentence denotes The Th2-biased stimulating capability of cpdm BMDC when co-cultured with allogeneic naïve CD4+ T cells is consistent with the Th2-dominant cytokine phenotype observed in cpdm mice.
T123 1755-1883 Sentence denotes 10.1371/journal.pone.0031809.g007 Figure 7 Stimulated cpdm BMDC induced Th2-biased cytokine production from naïve CD4+ T cells.
T124 1884-2042 Sentence denotes WT and cpdm BMDC (5×104 cells in 0.1 mL complete medium; MHC haplotype: H-2b) were incubated with medium, 100 ng/mL LPS, 25 µg/mL poly I:C or 5 µg/mL Pam3CYS.
T125 2043-2215 Sentence denotes After 24 hours, cells were washed with PBS and incubated with freshly isolated allogeneic naïve CD4+ T cells (2.5×105 cells in 0.1 mL complete medium; MHC haplotype: H-2d).
T126 2216-2321 Sentence denotes After 5 days, supernatants were collected and the secretion of IFNγ, IL4, and IL2 were measured by ELISA.
T127 2322-2479 Sentence denotes Negative controls are 1) stimulated BMDC without co-culture with allogeneic CD4+ T cells; 2) allogeneic CD4+ T cells without co-culture with stimulated BMDC.
T128 2480-2589 Sentence denotes Samples from both negative controls had no detectable production of the aforementioned cytokines (not shown).
T129 2590-2649 Sentence denotes Results are analyzed based on 2–4 mice per group. * P<0.05.

events-check-again

Id Subject Object Predicate Lexical cue Negation Speculation
T6522 158-165 Negative_regulation denotes absence
T6523 169-176 Protein denotes SHARPIN
T6524 353-361 Positive_regulation denotes elicited
T6525 369-373 Protein denotes IFNγ
T6526 374-384 Gene_expression denotes production
T6527 398-411 Gene_expression denotes concentration
T6528 415-419 Protein denotes IFNγ
T6529 467-472 Positive_regulation denotes lower true
T6530 580-584 Protein denotes TLR3
T6531 585-586 Protein denotes 4
T6532 587-595 Positive_regulation denotes agonists
T6533 587-595 Positive_regulation denotes agonists
T6534 601-605 Protein denotes TLR2
T6535 606-612 Binding denotes ligand
T6536 613-620 Protein denotes Pam3CYS
T6537 702-709 Protein denotes Pam3CYS
T6538 726-733 Positive_regulation denotes induced
T6539 741-745 Protein denotes IFNγ
T6540 746-756 Gene_expression denotes production
T6541 857-864 Protein denotes Pam3CYS
T6542 973-977 Protein denotes TLR2
T6543 1027-1030 Protein denotes IL4
T6544 1044-1052 Gene_expression denotes produced
T6545 1168-1178 Gene_expression denotes production
T6546 1205-1210 Protein denotes IL17A
T6547 1211-1220 Positive_regulation denotes following
T6548 1441-1444 Protein denotes IL2
T6549 1445-1455 Gene_expression denotes production
T6550 1531-1538 Positive_regulation denotes induced
T6551 1539-1543 Positive_regulation denotes more
T6552 1544-1547 Protein denotes IL2
T15724 2266-2275 Gene_expression denotes secretion true
T15725 2266-2275 Gene_expression denotes secretion true
T15726 2266-2275 Gene_expression denotes secretion true
T15727 2279-2283 Protein denotes IFNγ
T15728 2285-2288 Protein denotes IL4
T15729 2294-2297 Protein denotes IL2
T15730 2534-2544 Gene_expression denotes production true
T15731 2534-2544 Gene_expression denotes production true
T15732 2534-2544 Gene_expression denotes production true
R5295 T6523 T6522 themeOf SHARPIN,absence
R5296 T6525 T6526 themeOf IFNγ,production
R5297 T6526 T6524 themeOf production,elicited
R5298 T6527 T6529 themeOf concentration,lower
R5299 T6528 T6527 themeOf IFNγ,concentration
R5300 T6530 T6533 themeOf TLR3,agonists
R5301 T6531 T6532 themeOf 4,agonists
R5302 T6534 T6535 themeOf TLR2,ligand
R5303 T6536 T6535 themeOf Pam3CYS,ligand
R5304 T6537 T6538 causeOf Pam3CYS,induced
R5305 T6539 T6540 themeOf IFNγ,production
R5306 T6540 T6538 themeOf production,induced
R5307 T6543 T6544 themeOf IL4,produced
R5308 T6545 T6547 themeOf production,following
R5309 T6546 T6545 themeOf IL17A,production
R5310 T6548 T6549 themeOf IL2,production
R5311 T6550 T6551 themeOf induced,more
R5312 T6552 T6550 themeOf IL2,induced
R13160 T15727 T15726 themeOf IFNγ,secretion
R13161 T15727 T15730 themeOf IFNγ,production
R13162 T15728 T15724 themeOf IL4,secretion
R13163 T15728 T15731 themeOf IL4,production
R13164 T15729 T15732 themeOf IL2,production
R13165 T15729 T15725 themeOf IL2,secretion

bionlp-st-ge-2016-reference-tees

Id Subject Object Predicate Lexical cue
T6553 64-68 Protein denotes IL12
T6554 169-176 Protein denotes SHARPIN
T6555 69-79 Gene_expression denotes production
T6556 54-63 Negative_regulation denotes defective
T6557 295-299 Protein denotes CD4+
T6558 313-320 Protein denotes WT BMDC
T6559 415-419 Protein denotes IFNγ
T6560 526-529 Protein denotes Th1
T6561 601-620 Protein denotes TLR2 ligand Pam3CYS
T6562 669-672 Protein denotes Th1
T6563 677-680 Protein denotes Th2
T6564 657-663 Positive_regulation denotes induce
T6565 657-663 Positive_regulation denotes induce
T6566 718-725 Protein denotes WT BMDC
T6567 734-745 Protein denotes robust IFNγ
T6568 746-756 Gene_expression denotes production
T6569 726-733 Positive_regulation denotes induced
T6570 827-830 Protein denotes Th1
T6571 927-931 Protein denotes IL12
T6572 973-977 Protein denotes TLR2
T6573 819-826 Negative_regulation denotes reduced
T6574 932-942 Gene_expression denotes production
T6575 907-913 Negative_regulation denotes report
T6576 917-926 Negative_regulation denotes decreased
T6577 1027-1030 Protein denotes IL4
T6578 1182-1210 Protein denotes Th17-specific cytokine IL17A
T6579 1168-1178 Gene_expression denotes production
T6580 1354-1357 Protein denotes Th1
T6581 1441-1444 Protein denotes IL2
T6582 1523-1530 Protein denotes WT BMDC
T6583 1544-1547 Protein denotes IL2
T6584 1445-1455 Gene_expression denotes production
T6585 1531-1538 Positive_regulation denotes induced
T6586 1428-1437 Positive_regulation denotes effective
T6587 1664-1668 Protein denotes CD4+
T15733 1870-1874 Protein denotes CD4+
T15734 1941-1960 Protein denotes MHC haplotype: H-2b
T15735 2139-2143 Protein denotes CD4+
T15736 2194-2207 Protein denotes MHC haplotype
T15737 2279-2283 Protein denotes IFNγ
T15738 2285-2288 Protein denotes IL4
T15739 2294-2297 Protein denotes IL2
T15740 2266-2275 Localization denotes secretion
T15741 2266-2275 Localization denotes secretion
T15742 2266-2275 Localization denotes secretion
R5313 T6553 T6555 themeOf IL12,production
R5314 T6555 T6556 themeOf production,defective
R5315 T6562 T6564 themeOf Th1,induce
R5316 T6563 T6565 themeOf Th2,induce
R5317 T6566 T6569 causeOf WT BMDC,induced
R5318 T6567 T6568 themeOf robust IFNγ,production
R5319 T6568 T6569 themeOf production,induced
R5320 T6570 T6573 themeOf Th1,reduced
R5321 T6571 T6574 themeOf IL12,production
R5322 T6574 T6575 themeOf production,report
R5323 T6574 T6576 themeOf production,decreased
R5324 T6578 T6579 themeOf Th17-specific cytokine IL17A,production
R5325 T6581 T6584 themeOf IL2,production
R5326 T6582 T6585 causeOf WT BMDC,induced
R5327 T6583 T6585 themeOf IL2,induced
R5328 T6584 T6586 themeOf production,effective
R13166 T15737 T15740 themeOf IFNγ,secretion
R13167 T15738 T15741 themeOf IL4,secretion
R13168 T15739 T15742 themeOf IL2,secretion

bionlp-st-ge-2016-reference

Id Subject Object Predicate Lexical cue Negation Speculation
T5809 973-977 Protein denotes TLR2
T5810 1027-1030 Protein denotes IL4
T5811 1044-1052 Gene_expression denotes produced
T5812 1168-1178 Gene_expression denotes production
T5813 1205-1210 Protein denotes IL17A
T5814 1211-1220 Positive_regulation denotes following
T5815 1441-1444 Protein denotes IL2
T5816 1445-1455 Gene_expression denotes production
T5817 1531-1538 Positive_regulation denotes induced
T5818 1539-1543 Positive_regulation denotes more
T5819 1544-1547 Protein denotes IL2
T5789 158-165 Negative_regulation denotes absence
T5790 169-176 Protein denotes SHARPIN
T5791 353-361 Positive_regulation denotes elicited
T5792 369-373 Protein denotes IFNγ
T5793 374-384 Gene_expression denotes production
T5794 398-411 Gene_expression denotes concentration
T5795 415-419 Protein denotes IFNγ
T5796 467-472 Positive_regulation denotes lower true
T5797 580-584 Protein denotes TLR3
T5798 585-586 Protein denotes 4
T5799 587-595 Positive_regulation denotes agonists
T5800 587-595 Positive_regulation denotes agonists
T5801 601-605 Protein denotes TLR2
T5802 606-612 Binding denotes ligand
T5803 613-620 Protein denotes Pam3CYS
T5804 702-709 Protein denotes Pam3CYS
T5805 726-733 Positive_regulation denotes induced
T5806 741-745 Protein denotes IFNγ
T5807 746-756 Gene_expression denotes production
T5808 857-864 Protein denotes Pam3CYS
T15325 2266-2275 Gene_expression denotes secretion true
T15326 2266-2275 Gene_expression denotes secretion true
T15327 2266-2275 Gene_expression denotes secretion true
T15328 2279-2283 Protein denotes IFNγ
T15329 2285-2288 Protein denotes IL4
T15330 2294-2297 Protein denotes IL2
T15331 2534-2544 Gene_expression denotes production true
T15332 2534-2544 Gene_expression denotes production true
T15333 2534-2544 Gene_expression denotes production true
R4647 T5813 T5812 themeOf IL17A,production
R4648 T5815 T5816 themeOf IL2,production
R4649 T5817 T5818 themeOf induced,more
R4650 T5819 T5817 themeOf IL2,induced
R4633 T5790 T5789 themeOf SHARPIN,absence
R4634 T5792 T5793 themeOf IFNγ,production
R4635 T5793 T5791 themeOf production,elicited
R4636 T5794 T5796 themeOf concentration,lower
R4637 T5795 T5794 themeOf IFNγ,concentration
R4638 T5797 T5800 themeOf TLR3,agonists
R4639 T5798 T5799 themeOf 4,agonists
R4640 T5801 T5802 themeOf TLR2,ligand
R4641 T5803 T5802 themeOf Pam3CYS,ligand
R4642 T5804 T5805 causeOf Pam3CYS,induced
R4643 T5806 T5807 themeOf IFNγ,production
R4644 T5807 T5805 themeOf production,induced
R4645 T5810 T5811 themeOf IL4,produced
R4646 T5812 T5814 themeOf production,following
R12800 T15328 T15327 themeOf IFNγ,secretion
R12801 T15328 T15331 themeOf IFNγ,production
R12802 T15329 T15325 themeOf IL4,secretion
R12803 T15329 T15332 themeOf IL4,production
R12804 T15330 T15333 themeOf IL2,production
R12805 T15330 T15326 themeOf IL2,secretion

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T6433 169-176 Q9H0F6 denotes SHARPIN
T6434 295-298 P01730 denotes CD4
T6435 580-584 O15455 denotes TLR3
T6436 601-605 O60603 denotes TLR2
T6437 973-977 O60603 denotes TLR2
T6438 1027-1030 P05112 denotes IL4
T6439 1205-1210 Q16552 denotes IL17A
T6440 1441-1444 P60568 denotes IL2
T6441 1544-1547 P60568 denotes IL2
T6442 1664-1667 P01730 denotes CD4
T15504 1870-1873 P01730 denotes CD4
T15505 2139-2142 P01730 denotes CD4
T15506 2285-2288 P05112 denotes IL4
T15507 2294-2297 P60568 denotes IL2
T15508 2398-2401 P01730 denotes CD4
T15509 2426-2429 P01730 denotes CD4

test2

Id Subject Object Predicate Lexical cue Negation
T5763 158-165 Negative_regulation denotes absence
T5764 169-176 Protein denotes SHARPIN
T5765 353-361 Positive_regulation denotes elicited
T5766 369-373 Protein denotes IFNγ
T5767 374-384 Gene_expression denotes production true
T5768 398-411 Gene_expression denotes concentration
T5769 415-419 Protein denotes IFNγ
T5770 580-584 Protein denotes TLR3
T5771 585-586 Protein denotes 4
T5772 601-605 Protein denotes TLR2
T5773 606-612 Binding denotes ligand
T5774 613-620 Protein denotes Pam3CYS
T5775 702-709 Protein denotes Pam3CYS
T5776 726-733 Positive_regulation denotes induced
T5777 741-745 Protein denotes IFNγ
T5778 746-756 Gene_expression denotes production
T5779 857-864 Protein denotes Pam3CYS
T5780 963-972 Positive_regulation denotes following
T5781 973-977 Protein denotes TLR2
T5782 1027-1030 Protein denotes IL4
T5783 1168-1178 Gene_expression denotes production
T5784 1205-1210 Protein denotes IL17A
T5785 1211-1220 Positive_regulation denotes following
T5786 1441-1444 Protein denotes IL2
T5787 1445-1455 Gene_expression denotes production
T5788 1544-1547 Protein denotes IL2
R4621 T5764 T5763 themeOf SHARPIN,absence
R4622 T5766 T5767 themeOf IFNγ,production
R4623 T5767 T5765 themeOf production,elicited
R4624 T5769 T5768 themeOf IFNγ,concentration
R4625 T5772 T5773 themeOf TLR2,ligand
R4626 T5774 T5773 themeOf Pam3CYS,ligand
R4627 T5775 T5776 causeOf Pam3CYS,induced
R4628 T5777 T5778 themeOf IFNγ,production
R4629 T5778 T5776 themeOf production,induced
R4630 T5783 T5785 themeOf production,following
R4631 T5784 T5783 themeOf IL17A,production
R4632 T5786 T5787 themeOf IL2,production