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{"project":"GO-MF","denotations":[{"id":"T15271","span":{"begin":305,"end":315},"obj":"http://purl.obolibrary.org/obo/GO_0003823"},{"id":"T15272","span":{"begin":352,"end":356},"obj":"http://purl.obolibrary.org/obo/GO_0008384"},{"id":"T15273","span":{"begin":363,"end":367},"obj":"http://purl.obolibrary.org/obo/GO_0004707"},{"id":"T15274","span":{"begin":375,"end":378},"obj":"http://purl.obolibrary.org/obo/GO_0004707"}],"text":"10.1371/journal.pone.0031809.g006 Figure 6 Inhibition of NF-κB signaling in cpdm BMDC.\nWT and cpdm BMDC (2×106 cells in 0.5 mL complete medium) were stimulated with 100 ng/mL LPS (A) or 25 µg/mL poly I:C (B). At 0, 15, 30, and 60 minutes, whole-cell lysates were obtained and subject to immunoblots with antibodies against proteins involved in NF-κB, TBK1/IRF3, ERK1/2, and p38 signaling pathways. Beta-actin was used as loading control. (C) Cellular levels of p-IKK1/2 and p-IκBα in LPS- or poly I:C-stimulated BMDC were quantitated with ImageJ (NIH) and presented as trend lines. Results are representative of at least two independent experiments.\n\n"}

{"project":"GO-CC","denotations":[{"id":"T15275","span":{"begin":112,"end":117},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T15276","span":{"begin":246,"end":250},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T15277","span":{"begin":305,"end":315},"obj":"http://purl.obolibrary.org/obo/GO_0019815"},{"id":"T15278","span":{"begin":305,"end":315},"obj":"http://purl.obolibrary.org/obo/GO_0042571"}],"text":"10.1371/journal.pone.0031809.g006 Figure 6 Inhibition of NF-κB signaling in cpdm BMDC.\nWT and cpdm BMDC (2×106 cells in 0.5 mL complete medium) were stimulated with 100 ng/mL LPS (A) or 25 µg/mL poly I:C (B). At 0, 15, 30, and 60 minutes, whole-cell lysates were obtained and subject to immunoblots with antibodies against proteins involved in NF-κB, TBK1/IRF3, ERK1/2, and p38 signaling pathways. Beta-actin was used as loading control. (C) Cellular levels of p-IKK1/2 and p-IκBα in LPS- or poly I:C-stimulated BMDC were quantitated with ImageJ (NIH) and presented as trend lines. Results are representative of at least two independent experiments.\n\n"}

{"project":"sentences","denotations":[{"id":"T14993","span":{"begin":44,"end":87},"obj":"Sentence"},{"id":"T14994","span":{"begin":88,"end":209},"obj":"Sentence"},{"id":"T14995","span":{"begin":210,"end":398},"obj":"Sentence"},{"id":"T14996","span":{"begin":399,"end":582},"obj":"Sentence"},{"id":"T14997","span":{"begin":583,"end":650},"obj":"Sentence"},{"id":"T108","span":{"begin":0,"end":87},"obj":"Sentence"},{"id":"T109","span":{"begin":88,"end":209},"obj":"Sentence"},{"id":"T110","span":{"begin":210,"end":398},"obj":"Sentence"},{"id":"T111","span":{"begin":399,"end":582},"obj":"Sentence"},{"id":"T112","span":{"begin":583,"end":650},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"10.1371/journal.pone.0031809.g006 Figure 6 Inhibition of NF-κB signaling in cpdm BMDC.\nWT and cpdm BMDC (2×106 cells in 0.5 mL complete medium) were stimulated with 100 ng/mL LPS (A) or 25 µg/mL poly I:C (B). At 0, 15, 30, and 60 minutes, whole-cell lysates were obtained and subject to immunoblots with antibodies against proteins involved in NF-κB, TBK1/IRF3, ERK1/2, and p38 signaling pathways. Beta-actin was used as loading control. (C) Cellular levels of p-IKK1/2 and p-IκBα in LPS- or poly I:C-stimulated BMDC were quantitated with ImageJ (NIH) and presented as trend lines. Results are representative of at least two independent experiments.\n\n"}

{"project":"events-check-again","denotations":[{"id":"T15295","span":{"begin":352,"end":356},"obj":"Protein"},{"id":"T15296","span":{"begin":357,"end":361},"obj":"Protein"},{"id":"T15297","span":{"begin":363,"end":367},"obj":"Protein"},{"id":"T15298","span":{"begin":368,"end":369},"obj":"Protein"},{"id":"T15299","span":{"begin":399,"end":409},"obj":"Protein"},{"id":"T15300","span":{"begin":464,"end":468},"obj":"Protein"},{"id":"T15301","span":{"begin":469,"end":470},"obj":"Protein"},{"id":"T15302","span":{"begin":477,"end":481},"obj":"Protein"}],"text":"10.1371/journal.pone.0031809.g006 Figure 6 Inhibition of NF-κB signaling in cpdm BMDC.\nWT and cpdm BMDC (2×106 cells in 0.5 mL complete medium) were stimulated with 100 ng/mL LPS (A) or 25 µg/mL poly I:C (B). At 0, 15, 30, and 60 minutes, whole-cell lysates were obtained and subject to immunoblots with antibodies against proteins involved in NF-κB, TBK1/IRF3, ERK1/2, and p38 signaling pathways. Beta-actin was used as loading control. (C) Cellular levels of p-IKK1/2 and p-IκBα in LPS- or poly I:C-stimulated BMDC were quantitated with ImageJ (NIH) and presented as trend lines. Results are representative of at least two independent experiments.\n\n"}

{"project":"bionlp-st-ge-2016-reference-tees","denotations":[{"id":"T15303","span":{"begin":58,"end":63},"obj":"Protein"},{"id":"T15304","span":{"begin":44,"end":54},"obj":"Negative_regulation"},{"id":"T15305","span":{"begin":345,"end":350},"obj":"Protein"},{"id":"T15306","span":{"begin":352,"end":356},"obj":"Protein"},{"id":"T15307","span":{"begin":357,"end":361},"obj":"Protein"},{"id":"T15308","span":{"begin":363,"end":367},"obj":"Protein"},{"id":"T15309","span":{"begin":375,"end":378},"obj":"Protein"},{"id":"T15310","span":{"begin":399,"end":403},"obj":"Protein"},{"id":"T15311","span":{"begin":404,"end":409},"obj":"Protein"},{"id":"T15312","span":{"begin":475,"end":481},"obj":"Protein"},{"id":"T15313","span":{"begin":540,"end":546},"obj":"Protein"},{"id":"T15314","span":{"begin":548,"end":551},"obj":"Protein"},{"id":"T15315","span":{"begin":452,"end":458},"obj":"Gene_expression"}],"relations":[{"id":"R12792","pred":"themeOf","subj":"T15303","obj":"T15304"},{"id":"R12793","pred":"themeOf","subj":"T15312","obj":"T15315"}],"text":"10.1371/journal.pone.0031809.g006 Figure 6 Inhibition of NF-κB signaling in cpdm BMDC.\nWT and cpdm BMDC (2×106 cells in 0.5 mL complete medium) were stimulated with 100 ng/mL LPS (A) or 25 µg/mL poly I:C (B). At 0, 15, 30, and 60 minutes, whole-cell lysates were obtained and subject to immunoblots with antibodies against proteins involved in NF-κB, TBK1/IRF3, ERK1/2, and p38 signaling pathways. Beta-actin was used as loading control. (C) Cellular levels of p-IKK1/2 and p-IκBα in LPS- or poly I:C-stimulated BMDC were quantitated with ImageJ (NIH) and presented as trend lines. Results are representative of at least two independent experiments.\n\n"}

{"project":"bionlp-st-ge-2016-reference","denotations":[{"id":"T14990","span":{"begin":464,"end":468},"obj":"Protein"},{"id":"T14991","span":{"begin":469,"end":470},"obj":"Protein"},{"id":"T14992","span":{"begin":477,"end":481},"obj":"Protein"},{"id":"T14985","span":{"begin":352,"end":356},"obj":"Protein"},{"id":"T14986","span":{"begin":357,"end":361},"obj":"Protein"},{"id":"T14987","span":{"begin":363,"end":367},"obj":"Protein"},{"id":"T14988","span":{"begin":368,"end":369},"obj":"Protein"},{"id":"T14989","span":{"begin":399,"end":409},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"10.1371/journal.pone.0031809.g006 Figure 6 Inhibition of NF-κB signaling in cpdm BMDC.\nWT and cpdm BMDC (2×106 cells in 0.5 mL complete medium) were stimulated with 100 ng/mL LPS (A) or 25 µg/mL poly I:C (B). At 0, 15, 30, and 60 minutes, whole-cell lysates were obtained and subject to immunoblots with antibodies against proteins involved in NF-κB, TBK1/IRF3, ERK1/2, and p38 signaling pathways. Beta-actin was used as loading control. (C) Cellular levels of p-IKK1/2 and p-IκBα in LPS- or poly I:C-stimulated BMDC were quantitated with ImageJ (NIH) and presented as trend lines. Results are representative of at least two independent experiments.\n\n"}

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T15116","span":{"begin":352,"end":356},"obj":"Q9UHD2"},{"id":"T15117","span":{"begin":357,"end":361},"obj":"Q14653"},{"id":"T15118","span":{"begin":363,"end":367},"obj":"P27361"},{"id":"T15119","span":{"begin":375,"end":378},"obj":"O15264"},{"id":"T15120","span":{"begin":375,"end":378},"obj":"P53778"},{"id":"T15121","span":{"begin":375,"end":378},"obj":"Q16539"},{"id":"T15122","span":{"begin":375,"end":378},"obj":"Q15759"},{"id":"T15123","span":{"begin":399,"end":409},"obj":"P60709"},{"id":"T15124","span":{"begin":464,"end":468},"obj":"O15111"},{"id":"T15125","span":{"begin":464,"end":468},"obj":"Q60680-2"},{"id":"T15126","span":{"begin":477,"end":481},"obj":"P25963"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"10.1371/journal.pone.0031809.g006 Figure 6 Inhibition of NF-κB signaling in cpdm BMDC.\nWT and cpdm BMDC (2×106 cells in 0.5 mL complete medium) were stimulated with 100 ng/mL LPS (A) or 25 µg/mL poly I:C (B). At 0, 15, 30, and 60 minutes, whole-cell lysates were obtained and subject to immunoblots with antibodies against proteins involved in NF-κB, TBK1/IRF3, ERK1/2, and p38 signaling pathways. Beta-actin was used as loading control. (C) Cellular levels of p-IKK1/2 and p-IκBα in LPS- or poly I:C-stimulated BMDC were quantitated with ImageJ (NIH) and presented as trend lines. Results are representative of at least two independent experiments.\n\n"}

{"project":"test2","denotations":[{"id":"T14977","span":{"begin":352,"end":356},"obj":"Protein"},{"id":"T14978","span":{"begin":357,"end":361},"obj":"Protein"},{"id":"T14979","span":{"begin":363,"end":367},"obj":"Protein"},{"id":"T14980","span":{"begin":368,"end":369},"obj":"Protein"},{"id":"T14981","span":{"begin":399,"end":409},"obj":"Protein"},{"id":"T14982","span":{"begin":464,"end":468},"obj":"Protein"},{"id":"T14983","span":{"begin":469,"end":470},"obj":"Protein"},{"id":"T14984","span":{"begin":477,"end":481},"obj":"Protein"}],"text":"10.1371/journal.pone.0031809.g006 Figure 6 Inhibition of NF-κB signaling in cpdm BMDC.\nWT and cpdm BMDC (2×106 cells in 0.5 mL complete medium) were stimulated with 100 ng/mL LPS (A) or 25 µg/mL poly I:C (B). At 0, 15, 30, and 60 minutes, whole-cell lysates were obtained and subject to immunoblots with antibodies against proteins involved in NF-κB, TBK1/IRF3, ERK1/2, and p38 signaling pathways. Beta-actin was used as loading control. (C) Cellular levels of p-IKK1/2 and p-IκBα in LPS- or poly I:C-stimulated BMDC were quantitated with ImageJ (NIH) and presented as trend lines. Results are representative of at least two independent experiments.\n\n"}