PMC:3279418 / 15343-15593 JSONTXT

{"project":"pmc-enju-pas","denotations":[{"id":"T5200","span":{"begin":0,"end":16},"obj":"JJ"},{"id":"T5201","span":{"begin":17,"end":32},"obj":"NN"},{"id":"T5202","span":{"begin":33,"end":35},"obj":"IN"},{"id":"T5203","span":{"begin":36,"end":39},"obj":"DT"},{"id":"T5204","span":{"begin":40,"end":43},"obj":"NN"},{"id":"T5205","span":{"begin":44,"end":50},"obj":"NN"},{"id":"T5206","span":{"begin":51,"end":52},"obj":"-LRB-"},{"id":"T5207","span":{"begin":52,"end":58},"obj":"NN"},{"id":"T5208","span":{"begin":58,"end":59},"obj":"-RRB-"},{"id":"T5209","span":{"begin":60,"end":62},"obj":"VB"},{"id":"T5210","span":{"begin":63,"end":65},"obj":"DT"},{"id":"T5211","span":{"begin":66,"end":75},"obj":"JJ"},{"id":"T5212","span":{"begin":76,"end":80},"obj":"NN"},{"id":"T5213","span":{"begin":81,"end":83},"obj":"IN"},{"id":"T5214","span":{"begin":84,"end":89},"obj":"NN"},{"id":"T5215","span":{"begin":90,"end":99},"obj":"NN"},{"id":"T5216","span":{"begin":99,"end":100},"obj":"-COMMA-"},{"id":"T5217","span":{"begin":101,"end":109},"obj":"VB"},{"id":"T5218","span":{"begin":110,"end":125},"obj":"NN"},{"id":"T5219","span":{"begin":126,"end":129},"obj":"CC"},{"id":"T5220","span":{"begin":130,"end":149},"obj":"JJ"},{"id":"T5221","span":{"begin":150,"end":161},"obj":"NN"},{"id":"T5222","span":{"begin":162,"end":164},"obj":"IN"},{"id":"T5223","span":{"begin":165,"end":168},"obj":"DT"},{"id":"T5224","span":{"begin":169,"end":174},"obj":"NN"},{"id":"T5225","span":{"begin":175,"end":184},"obj":"NN"},{"id":"T5226","span":{"begin":185,"end":189},"obj":"NN"},{"id":"T5227","span":{"begin":190,"end":192},"obj":"TO"},{"id":"T5228","span":{"begin":193,"end":200},"obj":"VB"},{"id":"T5229","span":{"begin":201,"end":204},"obj":"DT"},{"id":"T5230","span":{"begin":205,"end":210},"obj":"NN"},{"id":"T5231","span":{"begin":211,"end":224},"obj":"NN"},{"id":"T5232","span":{"begin":225,"end":232},"obj":"NN"},{"id":"T5233","span":{"begin":233,"end":237},"obj":"IN"},{"id":"T5234","span":{"begin":238,"end":241},"obj":"DT"},{"id":"T5235","span":{"begin":242,"end":249},"obj":"NN"}],"relations":[{"id":"R4334","pred":"arg1Of","subj":"T5201","obj":"T5200"},{"id":"R4335","pred":"arg1Of","subj":"T5201","obj":"T5202"},{"id":"R4336","pred":"arg1Of","subj":"T5201","obj":"T5209"},{"id":"R4337","pred":"arg2Of","subj":"T5205","obj":"T5202"},{"id":"R4338","pred":"arg1Of","subj":"T5205","obj":"T5203"},{"id":"R4339","pred":"arg1Of","subj":"T5205","obj":"T5204"},{"id":"R4340","pred":"arg1Of","subj":"T5205","obj":"T5206"},{"id":"R4341","pred":"arg2Of","subj":"T5207","obj":"T5206"},{"id":"R4342","pred":"arg3Of","subj":"T5208","obj":"T5206"},{"id":"R4343","pred":"arg1Of","subj":"T5209","obj":"T5216"},{"id":"R4344","pred":"modOf","subj":"T5209","obj":"T5217"},{"id":"R4345","pred":"arg2Of","subj":"T5212","obj":"T5209"},{"id":"R4346","pred":"arg1Of","subj":"T5212","obj":"T5210"},{"id":"R4347","pred":"arg1Of","subj":"T5212","obj":"T5211"},{"id":"R4348","pred":"arg1Of","subj":"T5212","obj":"T5213"},{"id":"R4349","pred":"arg2Of","subj":"T5215","obj":"T5213"},{"id":"R4350","pred":"arg1Of","subj":"T5215","obj":"T5214"},{"id":"R4351","pred":"arg1Of","subj":"T5218","obj":"T5219"},{"id":"R4352","pred":"arg2Of","subj":"T5219","obj":"T5217"},{"id":"R4353","pred":"arg1Of","subj":"T5219","obj":"T5222"},{"id":"R4354","pred":"arg1Of","subj":"T5219","obj":"T5228"},{"id":"R4355","pred":"arg2Of","subj":"T5221","obj":"T5219"},{"id":"R4356","pred":"arg1Of","subj":"T5221","obj":"T5220"},{"id":"R4357","pred":"arg2Of","subj":"T5226","obj":"T5222"},{"id":"R4358","pred":"arg1Of","subj":"T5226","obj":"T5223"},{"id":"R4359","pred":"arg1Of","subj":"T5226","obj":"T5224"},{"id":"R4360","pred":"arg1Of","subj":"T5226","obj":"T5225"},{"id":"R4361","pred":"arg3Of","subj":"T5228","obj":"T5217"},{"id":"R4362","pred":"arg1Of","subj":"T5228","obj":"T5227"},{"id":"R4363","pred":"arg1Of","subj":"T5228","obj":"T5233"},{"id":"R4364","pred":"arg2Of","subj":"T5232","obj":"T5228"},{"id":"R4365","pred":"arg1Of","subj":"T5232","obj":"T5229"},{"id":"R4366","pred":"arg1Of","subj":"T5232","obj":"T5230"},{"id":"R4367","pred":"arg1Of","subj":"T5232","obj":"T5231"},{"id":"R4368","pred":"arg2Of","subj":"T5235","obj":"T5233"},{"id":"R4369","pred":"arg1Of","subj":"T5235","obj":"T5234"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"text":"Stimulus-induced phosphorylation of the IκB kinase (IKK1/2) is an essential step in NF-κB signaling, allowing phosphorylation and proteasome-mediated degradation of the NF-κB inhibitor IκBα to release the NF-κB transcription factors into the nucleus."}

{"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T4785","span":{"begin":0,"end":16},"obj":"JJ"},{"id":"T4786","span":{"begin":17,"end":32},"obj":"NN"},{"id":"T4787","span":{"begin":33,"end":35},"obj":"IN"},{"id":"T4788","span":{"begin":36,"end":39},"obj":"DT"},{"id":"T4789","span":{"begin":40,"end":43},"obj":"NNP"},{"id":"T4790","span":{"begin":44,"end":50},"obj":"NN"},{"id":"T4791","span":{"begin":51,"end":52},"obj":"-LRB-"},{"id":"T4792","span":{"begin":52,"end":58},"obj":"NNP"},{"id":"T4793","span":{"begin":58,"end":59},"obj":"-RRB-"},{"id":"T4794","span":{"begin":60,"end":62},"obj":"VBZ"},{"id":"T4795","span":{"begin":63,"end":65},"obj":"DT"},{"id":"T4796","span":{"begin":66,"end":75},"obj":"JJ"},{"id":"T4797","span":{"begin":76,"end":80},"obj":"NN"},{"id":"T4798","span":{"begin":81,"end":83},"obj":"IN"},{"id":"T4799","span":{"begin":84,"end":89},"obj":"JJ"},{"id":"T4800","span":{"begin":90,"end":99},"obj":"VBG"},{"id":"T4801","span":{"begin":99,"end":100},"obj":","},{"id":"T4802","span":{"begin":101,"end":109},"obj":"VBG"},{"id":"T4803","span":{"begin":110,"end":125},"obj":"NN"},{"id":"T4804","span":{"begin":126,"end":129},"obj":"CC"},{"id":"T4805","span":{"begin":130,"end":149},"obj":"JJ"},{"id":"T4806","span":{"begin":150,"end":161},"obj":"NN"},{"id":"T4807","span":{"begin":162,"end":164},"obj":"IN"},{"id":"T4808","span":{"begin":165,"end":168},"obj":"DT"},{"id":"T4809","span":{"begin":169,"end":174},"obj":"NNP"},{"id":"T4810","span":{"begin":175,"end":184},"obj":"NN"},{"id":"T4811","span":{"begin":185,"end":189},"obj":"NNP"},{"id":"T4812","span":{"begin":190,"end":192},"obj":"TO"},{"id":"T4813","span":{"begin":193,"end":200},"obj":"VB"},{"id":"T4814","span":{"begin":201,"end":204},"obj":"DT"},{"id":"T4815","span":{"begin":205,"end":210},"obj":"JJ"},{"id":"T4816","span":{"begin":211,"end":224},"obj":"NN"},{"id":"T4817","span":{"begin":225,"end":232},"obj":"NNS"},{"id":"T4818","span":{"begin":233,"end":237},"obj":"IN"},{"id":"T4819","span":{"begin":238,"end":241},"obj":"DT"},{"id":"T4820","span":{"begin":242,"end":249},"obj":"NN"},{"id":"T4821","span":{"begin":249,"end":250},"obj":"."}],"relations":[{"id":"R3920","pred":"amod","subj":"T4785","obj":"T4786"},{"id":"R3921","pred":"nsubj","subj":"T4786","obj":"T4794"},{"id":"R3922","pred":"prep","subj":"T4787","obj":"T4786"},{"id":"R3923","pred":"det","subj":"T4788","obj":"T4790"},{"id":"R3924","pred":"compound","subj":"T4789","obj":"T4790"},{"id":"R3925","pred":"pobj","subj":"T4790","obj":"T4787"},{"id":"R3926","pred":"punct","subj":"T4791","obj":"T4792"},{"id":"R3927","pred":"appos","subj":"T4792","obj":"T4790"},{"id":"R3928","pred":"punct","subj":"T4793","obj":"T4790"},{"id":"R3929","pred":"ROOT","subj":"T4794","obj":"T4794"},{"id":"R3930","pred":"det","subj":"T4795","obj":"T4797"},{"id":"R3931","pred":"amod","subj":"T4796","obj":"T4797"},{"id":"R3932","pred":"attr","subj":"T4797","obj":"T4794"},{"id":"R3933","pred":"prep","subj":"T4798","obj":"T4797"},{"id":"R3934","pred":"amod","subj":"T4799","obj":"T4800"},{"id":"R3935","pred":"pcomp","subj":"T4800","obj":"T4798"},{"id":"R3936","pred":"punct","subj":"T4801","obj":"T4800"},{"id":"R3937","pred":"conj","subj":"T4802","obj":"T4800"},{"id":"R3938","pred":"amod","subj":"T4803","obj":"T4806"},{"id":"R3939","pred":"cc","subj":"T4804","obj":"T4803"},{"id":"R3940","pred":"conj","subj":"T4805","obj":"T4803"},{"id":"R3941","pred":"dobj","subj":"T4806","obj":"T4802"},{"id":"R3942","pred":"prep","subj":"T4807","obj":"T4806"},{"id":"R3943","pred":"det","subj":"T4808","obj":"T4810"},{"id":"R3944","pred":"compound","subj":"T4809","obj":"T4810"},{"id":"R3945","pred":"pobj","subj":"T4810","obj":"T4807"},{"id":"R3946","pred":"appos","subj":"T4811","obj":"T4806"},{"id":"R3947","pred":"aux","subj":"T4812","obj":"T4813"},{"id":"R3948","pred":"ccomp","subj":"T4813","obj":"T4802"},{"id":"R3949","pred":"det","subj":"T4814","obj":"T4817"},{"id":"R3950","pred":"amod","subj":"T4815","obj":"T4817"},{"id":"R3951","pred":"compound","subj":"T4816","obj":"T4817"},{"id":"R3952","pred":"dobj","subj":"T4817","obj":"T4813"},{"id":"R3953","pred":"prep","subj":"T4818","obj":"T4813"},{"id":"R3954","pred":"det","subj":"T4819","obj":"T4820"},{"id":"R3955","pred":"pobj","subj":"T4820","obj":"T4818"},{"id":"R3956","pred":"punct","subj":"T4821","obj":"T4794"}],"text":"Stimulus-induced phosphorylation of the IκB kinase (IKK1/2) is an essential step in NF-κB signaling, allowing phosphorylation and proteasome-mediated degradation of the NF-κB inhibitor IκBα to release the NF-κB transcription factors into the nucleus."}

{"project":"GO-BP","denotations":[{"id":"T5384","span":{"begin":90,"end":99},"obj":"http://purl.obolibrary.org/obo/GO_0023052"},{"id":"T5397","span":{"begin":211,"end":224},"obj":"http://purl.obolibrary.org/obo/GO_0006351"},{"id":"T5411","span":{"begin":17,"end":32},"obj":"http://purl.obolibrary.org/obo/GO_0016310"},{"id":"T5412","span":{"begin":110,"end":125},"obj":"http://purl.obolibrary.org/obo/GO_0016310"},{"id":"T5414","span":{"begin":17,"end":43},"obj":"http://purl.obolibrary.org/obo/GO_0007252"},{"id":"T5415","span":{"begin":169,"end":184},"obj":"http://purl.obolibrary.org/obo/GO_0007252"},{"id":"T5416","span":{"begin":150,"end":161},"obj":"http://purl.obolibrary.org/obo/GO_0009056"},{"id":"T5417","span":{"begin":169,"end":184},"obj":"http://purl.obolibrary.org/obo/GO_0032088"},{"id":"T5418","span":{"begin":211,"end":249},"obj":"http://purl.obolibrary.org/obo/GO_0042991"}],"text":"Stimulus-induced phosphorylation of the IκB kinase (IKK1/2) is an essential step in NF-κB signaling, allowing phosphorylation and proteasome-mediated degradation of the NF-κB inhibitor IκBα to release the NF-κB transcription factors into the nucleus."}

{"project":"GO-CC","denotations":[{"id":"T5435","span":{"begin":130,"end":140},"obj":"http://purl.obolibrary.org/obo/GO_0000502"},{"id":"T5436","span":{"begin":242,"end":249},"obj":"http://purl.obolibrary.org/obo/GO_0005634"}],"text":"Stimulus-induced phosphorylation of the IκB kinase (IKK1/2) is an essential step in NF-κB signaling, allowing phosphorylation and proteasome-mediated degradation of the NF-κB inhibitor IκBα to release the NF-κB transcription factors into the nucleus."}

{"project":"sentences","denotations":[{"id":"T4485","span":{"begin":0,"end":250},"obj":"Sentence"},{"id":"T104","span":{"begin":0,"end":250},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Stimulus-induced phosphorylation of the IκB kinase (IKK1/2) is an essential step in NF-κB signaling, allowing phosphorylation and proteasome-mediated degradation of the NF-κB inhibitor IκBα to release the NF-κB transcription factors into the nucleus."}

{"project":"events-check-again","denotations":[{"id":"T5601","span":{"begin":52,"end":56},"obj":"Protein"},{"id":"T5602","span":{"begin":57,"end":58},"obj":"Protein"},{"id":"T5603","span":{"begin":101,"end":109},"obj":"Positive_regulation"},{"id":"T5604","span":{"begin":101,"end":109},"obj":"Positive_regulation"},{"id":"T5605","span":{"begin":110,"end":125},"obj":"Phosphorylation"},{"id":"T5606","span":{"begin":141,"end":149},"obj":"Positive_regulation"},{"id":"T5607","span":{"begin":150,"end":161},"obj":"Protein_catabolism"},{"id":"T5608","span":{"begin":185,"end":189},"obj":"Protein"}],"relations":[{"id":"R4527","pred":"themeOf","subj":"T5605","obj":"T5604"},{"id":"R4528","pred":"themeOf","subj":"T5607","obj":"T5603"},{"id":"R4529","pred":"themeOf","subj":"T5607","obj":"T5606"},{"id":"R4530","pred":"themeOf","subj":"T5608","obj":"T5605"},{"id":"R4531","pred":"themeOf","subj":"T5608","obj":"T5607"}],"text":"Stimulus-induced phosphorylation of the IκB kinase (IKK1/2) is an essential step in NF-κB signaling, allowing phosphorylation and proteasome-mediated degradation of the NF-κB inhibitor IκBα to release the NF-κB transcription factors into the nucleus."}

{"project":"bionlp-st-ge-2016-reference-tees","denotations":[{"id":"T5685","span":{"begin":40,"end":50},"obj":"Protein"},{"id":"T5686","span":{"begin":52,"end":58},"obj":"Protein"},{"id":"T5687","span":{"begin":84,"end":89},"obj":"Protein"},{"id":"T5688","span":{"begin":169,"end":174},"obj":"Protein"},{"id":"T5689","span":{"begin":185,"end":189},"obj":"Protein"},{"id":"T5690","span":{"begin":205,"end":232},"obj":"Protein"},{"id":"T5691","span":{"begin":17,"end":32},"obj":"Phosphorylation"},{"id":"T5692","span":{"begin":17,"end":32},"obj":"Phosphorylation"},{"id":"T5693","span":{"begin":110,"end":125},"obj":"Phosphorylation"},{"id":"T5694","span":{"begin":110,"end":125},"obj":"Phosphorylation"},{"id":"T5695","span":{"begin":150,"end":161},"obj":"Protein_catabolism"},{"id":"T5696","span":{"begin":150,"end":161},"obj":"Protein_catabolism"},{"id":"T5697","span":{"begin":150,"end":161},"obj":"Protein_catabolism"},{"id":"T5698","span":{"begin":242,"end":249},"obj":"Entity"},{"id":"T5699","span":{"begin":0,"end":16},"obj":"Positive_regulation"},{"id":"T5700","span":{"begin":0,"end":16},"obj":"Positive_regulation"},{"id":"T5701","span":{"begin":101,"end":109},"obj":"Positive_regulation"},{"id":"T5702","span":{"begin":101,"end":109},"obj":"Positive_regulation"},{"id":"T5703","span":{"begin":101,"end":109},"obj":"Positive_regulation"},{"id":"T5704","span":{"begin":130,"end":149},"obj":"Positive_regulation"},{"id":"T5705","span":{"begin":130,"end":149},"obj":"Positive_regulation"},{"id":"T5706","span":{"begin":130,"end":149},"obj":"Positive_regulation"},{"id":"T5707","span":{"begin":193,"end":200},"obj":"Localization"}],"relations":[{"id":"R4568","pred":"themeOf","subj":"T5685","obj":"T5691"},{"id":"R4569","pred":"themeOf","subj":"T5686","obj":"T5692"},{"id":"R4570","pred":"themeOf","subj":"T5686","obj":"T5695"},{"id":"R4571","pred":"themeOf","subj":"T5688","obj":"T5693"},{"id":"R4572","pred":"themeOf","subj":"T5688","obj":"T5696"},{"id":"R4573","pred":"themeOf","subj":"T5689","obj":"T5694"},{"id":"R4574","pred":"themeOf","subj":"T5689","obj":"T5697"},{"id":"R4575","pred":"themeOf","subj":"T5690","obj":"T5707"},{"id":"R4576","pred":"themeOf","subj":"T5691","obj":"T5699"},{"id":"R4577","pred":"themeOf","subj":"T5692","obj":"T5700"},{"id":"R4578","pred":"themeOf","subj":"T5695","obj":"T5701"},{"id":"R4579","pred":"themeOf","subj":"T5695","obj":"T5704"},{"id":"R4580","pred":"themeOf","subj":"T5696","obj":"T5702"},{"id":"R4581","pred":"themeOf","subj":"T5696","obj":"T5705"},{"id":"R4582","pred":"themeOf","subj":"T5697","obj":"T5703"},{"id":"R4583","pred":"themeOf","subj":"T5697","obj":"T5706"},{"id":"R4584","pred":"locationOf","subj":"T5698","obj":"T5707"}],"text":"Stimulus-induced phosphorylation of the IκB kinase (IKK1/2) is an essential step in NF-κB signaling, allowing phosphorylation and proteasome-mediated degradation of the NF-κB inhibitor IκBα to release the NF-κB transcription factors into the nucleus."}

{"project":"bionlp-st-ge-2016-reference","denotations":[{"id":"T4443","span":{"begin":52,"end":56},"obj":"Protein"},{"id":"T4444","span":{"begin":57,"end":58},"obj":"Protein"},{"id":"T4445","span":{"begin":101,"end":109},"obj":"Positive_regulation"},{"id":"T4446","span":{"begin":101,"end":109},"obj":"Positive_regulation"},{"id":"T4447","span":{"begin":110,"end":125},"obj":"Phosphorylation"},{"id":"T4448","span":{"begin":141,"end":149},"obj":"Positive_regulation"},{"id":"T4449","span":{"begin":150,"end":161},"obj":"Protein_catabolism"},{"id":"T4450","span":{"begin":185,"end":189},"obj":"Protein"}],"relations":[{"id":"R3609","pred":"themeOf","subj":"T4447","obj":"T4446"},{"id":"R3610","pred":"themeOf","subj":"T4449","obj":"T4445"},{"id":"R3611","pred":"themeOf","subj":"T4449","obj":"T4448"},{"id":"R3612","pred":"themeOf","subj":"T4450","obj":"T4447"},{"id":"R3613","pred":"themeOf","subj":"T4450","obj":"T4449"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Stimulus-induced phosphorylation of the IκB kinase (IKK1/2) is an essential step in NF-κB signaling, allowing phosphorylation and proteasome-mediated degradation of the NF-κB inhibitor IκBα to release the NF-κB transcription factors into the nucleus."}

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T5337","span":{"begin":40,"end":50},"obj":"Q60680-2"},{"id":"T5338","span":{"begin":40,"end":50},"obj":"O15111"},{"id":"T5339","span":{"begin":52,"end":56},"obj":"O15111"},{"id":"T5340","span":{"begin":52,"end":56},"obj":"Q60680-2"},{"id":"T5341","span":{"begin":185,"end":189},"obj":"P25963"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"Stimulus-induced phosphorylation of the IκB kinase (IKK1/2) is an essential step in NF-κB signaling, allowing phosphorylation and proteasome-mediated degradation of the NF-κB inhibitor IκBα to release the NF-κB transcription factors into the nucleus."}

{"project":"test2","denotations":[{"id":"T4384","span":{"begin":52,"end":56},"obj":"Protein"},{"id":"T4385","span":{"begin":57,"end":58},"obj":"Protein"},{"id":"T4386","span":{"begin":110,"end":125},"obj":"Phosphorylation"},{"id":"T4387","span":{"begin":150,"end":161},"obj":"Protein_catabolism"},{"id":"T4388","span":{"begin":185,"end":189},"obj":"Protein"},{"id":"T4389","span":{"begin":193,"end":200},"obj":"Localization"}],"relations":[{"id":"R3584","pred":"themeOf","subj":"T4388","obj":"T4386"},{"id":"R3585","pred":"themeOf","subj":"T4388","obj":"T4389"},{"id":"R3586","pred":"themeOf","subj":"T4388","obj":"T4387"}],"text":"Stimulus-induced phosphorylation of the IκB kinase (IKK1/2) is an essential step in NF-κB signaling, allowing phosphorylation and proteasome-mediated degradation of the NF-κB inhibitor IκBα to release the NF-κB transcription factors into the nucleus."}