PMC:3279418 / 1062-1234 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T558	1-2	-COMMA-	denotes	,
T559	3-6	CC	denotes	and
T560	7-11	NN	denotes	CD86
T561	13-20	RB	denotes	However
T562	20-21	-COMMA-	denotes	,
T563	22-32	VB	denotes	stimulated
T564	33-50	JJ	denotes	SHARPIN-deficient
T565	51-55	NN	denotes	BMDC
T566	56-59	VB	denotes	had
T567	60-67	VB	denotes	reduced
T568	68-81	NN	denotes	transcription
T569	82-85	CC	denotes	and
T570	86-95	NN	denotes	secretion
T571	96-98	IN	denotes	of
T572	99-115	JJ	denotes	pro-inflammatory
T573	116-125	NN	denotes	mediators
T574	126-129	NN	denotes	IL6
T575	129-130	-COMMA-	denotes	,
T576	131-138	NN	denotes	IL12P70
T577	138-139	-COMMA-	denotes	,
T578	140-145	NN	denotes	GMCSF
T579	145-146	-COMMA-	denotes	,
T580	147-150	CC	denotes	and
T581	151-157	JJ	denotes	nitric
T582	158-163	NN	denotes	oxide
T583	165-171	JJ	denotes	Mutant
R477	T559	T558	arg1Of	and,","
R478	T560	T559	arg2Of	CD86,and
R479	T565	T563	arg1Of	BMDC,stimulated
R480	T565	T564	arg1Of	BMDC,SHARPIN-deficient
R481	T565	T566	arg1Of	BMDC,had
R482	T565	T567	arg1Of	BMDC,reduced
R483	T567	T561	arg1Of	reduced,However
R484	T567	T562	arg1Of	reduced,","
R485	T567	T566	arg2Of	reduced,had
R486	T568	T569	arg1Of	transcription,and
R487	T569	T567	arg2Of	and,reduced
R488	T569	T571	arg1Of	and,of
R489	T570	T569	arg2Of	secretion,and
R490	T573	T572	arg1Of	mediators,pro-inflammatory
R491	T574	T575	arg1Of	IL6,","
R492	T575	T577	arg1Of	",",","
R493	T576	T575	arg2Of	IL12P70,","
R494	T577	T580	arg1Of	",",and
R495	T578	T577	arg2Of	GMCSF,","
R496	T580	T571	arg2Of	and,of
R497	T580	T573	arg1Of	and,mediators
R498	T580	T579	arg1Of	and,","
R499	T582	T580	arg2Of	oxide,and
R500	T582	T581	arg1Of	oxide,nitric

Id	Subject	Object	Predicate	Lexical cue
T282	1-2	,	denotes	,
T283	3-6	CC	denotes	and
T284	7-11	NNP	denotes	CD86
T285	11-12	.	denotes	.
T286	13-20	RB	denotes	However
T287	20-21	,	denotes	,
T288	22-32	VBD	denotes	stimulated
T289	33-50	JJ	denotes	SHARPIN-deficient
T290	51-55	NNP	denotes	BMDC
T291	56-59	VBD	denotes	had
T292	60-67	VBN	denotes	reduced
T293	68-81	NN	denotes	transcription
T294	82-85	CC	denotes	and
T295	86-95	NN	denotes	secretion
T296	96-98	IN	denotes	of
T297	99-115	JJ	denotes	pro-inflammatory
T298	116-125	NNS	denotes	mediators
T299	126-129	NNP	denotes	IL6
T300	129-130	,	denotes	,
T301	131-138	NNP	denotes	IL12P70
T302	138-139	,	denotes	,
T303	140-145	NNP	denotes	GMCSF
T304	145-146	,	denotes	,
T305	147-150	CC	denotes	and
T306	151-157	JJ	denotes	nitric
T307	158-163	NN	denotes	oxide
T308	163-164	.	denotes	.
T309	165-171	JJ	denotes	Mutant
R202	T286	T288	advmod	However,stimulated
R203	T287	T288	punct	",",stimulated
R204	T288	T288	ROOT	stimulated,stimulated
R205	T289	T290	compound	SHARPIN-deficient,BMDC
R206	T290	T292	nsubj	BMDC,reduced
R207	T291	T292	aux	had,reduced
R208	T292	T288	ccomp	reduced,stimulated
R209	T293	T292	dobj	transcription,reduced
R210	T294	T293	cc	and,transcription
R211	T295	T293	conj	secretion,transcription
R212	T296	T293	prep	of,transcription
R213	T297	T298	amod	pro-inflammatory,mediators
R214	T298	T296	pobj	mediators,of
R215	T299	T292	dobj	IL6,reduced
R216	T300	T299	punct	",",IL6
R217	T301	T299	conj	IL12P70,IL6
R218	T302	T301	punct	",",IL12P70
R219	T303	T301	conj	GMCSF,IL12P70
R220	T304	T303	punct	",",GMCSF
R221	T305	T303	cc	and,GMCSF
R222	T306	T307	amod	nitric,oxide
R223	T307	T303	conj	oxide,GMCSF
R224	T308	T292	punct	.,reduced

Id	Subject	Object	Predicate	Lexical cue
T704	86-95	http://purl.obolibrary.org/obo/GO_0046903	denotes	secretion
T706	68-81	http://purl.obolibrary.org/obo/GO_0006351	denotes	transcription

Id	Subject	Object	Predicate	Lexical cue
T114	13-164	Sentence	denotes	However, stimulated SHARPIN-deficient BMDC had reduced transcription and secretion of pro-inflammatory mediators IL6, IL12P70, GMCSF, and nitric oxide.
T9	13-164	Sentence	denotes	However, stimulated SHARPIN-deficient BMDC had reduced transcription and secretion of pro-inflammatory mediators IL6, IL12P70, GMCSF, and nitric oxide.

Id	Subject	Object	Predicate	Lexical cue
T814	7-11	Protein	denotes	CD86
T815	33-40	Protein	denotes	SHARPIN
T816	41-50	Negative_regulation	denotes	deficient
T817	60-67	Negative_regulation	denotes	reduced
T818	60-67	Negative_regulation	denotes	reduced
T819	60-67	Negative_regulation	denotes	reduced
T820	60-67	Negative_regulation	denotes	reduced
T821	68-81	Transcription	denotes	transcription
T822	68-81	Transcription	denotes	transcription
T823	86-95	Gene_expression	denotes	secretion
T824	86-95	Gene_expression	denotes	secretion
T825	126-129	Protein	denotes	IL6
T826	140-145	Protein	denotes	GMCSF
R711	T826	T822	themeOf	GMCSF,transcription
R712	T826	T823	themeOf	GMCSF,secretion
R700	T815	T816	themeOf	SHARPIN,deficient
R701	T816	T818	causeOf	deficient,reduced
R702	T816	T820	causeOf	deficient,reduced
R703	T816	T819	causeOf	deficient,reduced
R704	T816	T817	causeOf	deficient,reduced
R705	T821	T818	themeOf	transcription,reduced
R706	T822	T820	themeOf	transcription,reduced
R707	T823	T817	themeOf	secretion,reduced
R708	T824	T819	themeOf	secretion,reduced
R709	T825	T821	themeOf	IL6,transcription
R710	T825	T824	themeOf	IL6,secretion

Id	Subject	Object	Predicate	Lexical cue
T867	7-11	Protein	denotes	CD86
T874	33-40	Protein	denotes	SHARPIN
T875	126-129	Protein	denotes	IL6
T876	131-138	Protein	denotes	IL12P70
T877	140-145	Protein	denotes	GMCSF
T878	41-50	Negative_regulation	denotes	deficient
T879	68-81	Transcription	denotes	transcription
T880	68-81	Transcription	denotes	transcription
T881	68-81	Transcription	denotes	transcription
T882	86-95	Localization	denotes	secretion
T883	86-95	Localization	denotes	secretion
T884	86-95	Localization	denotes	secretion
T885	60-67	Negative_regulation	denotes	reduced
T886	60-67	Negative_regulation	denotes	reduced
T887	60-67	Negative_regulation	denotes	reduced
R650	T874	T878	themeOf	SHARPIN,deficient
R651	T875	T879	themeOf	IL6,transcription
R652	T875	T882	themeOf	IL6,secretion
R653	T876	T880	themeOf	IL12P70,transcription
R654	T876	T883	themeOf	IL12P70,secretion
R655	T877	T881	themeOf	GMCSF,transcription
R656	T877	T884	themeOf	GMCSF,secretion
R657	T879	T885	themeOf	transcription,reduced
R658	T880	T886	themeOf	transcription,reduced
R659	T881	T887	themeOf	transcription,reduced

Id	Subject	Object	Predicate	Lexical cue
T93	86-95	Gene_expression	denotes	secretion
T94	126-129	Protein	denotes	IL6
T95	140-145	Protein	denotes	GMCSF
T83	7-11	Protein	denotes	CD86
T84	33-40	Protein	denotes	SHARPIN
T85	41-50	Negative_regulation	denotes	deficient
T86	60-67	Negative_regulation	denotes	reduced
T87	60-67	Negative_regulation	denotes	reduced
T88	60-67	Negative_regulation	denotes	reduced
T89	60-67	Negative_regulation	denotes	reduced
T90	68-81	Transcription	denotes	transcription
T91	68-81	Transcription	denotes	transcription
T92	86-95	Gene_expression	denotes	secretion
R36	T94	T90	themeOf	IL6,transcription
R37	T94	T93	themeOf	IL6,secretion
R38	T95	T91	themeOf	GMCSF,transcription
R678	T85	T87	causeOf	deficient,reduced
R679	T85	T89	causeOf	deficient,reduced
R680	T85	T88	causeOf	deficient,reduced
R681	T85	T86	causeOf	deficient,reduced
R682	T90	T87	themeOf	transcription,reduced
R683	T91	T89	themeOf	transcription,reduced
R684	T92	T86	themeOf	secretion,reduced
R35	T93	T88	themeOf	secretion,reduced
R677	T84	T85	themeOf	SHARPIN,deficient
R39	T95	T92	themeOf	GMCSF,secretion

Id	Subject	Object	Predicate	Lexical cue
T674	7-11	P42081	denotes	CD86
T675	33-40	Q9H0F6	denotes	SHARPIN
T676	126-129	P05231	denotes	IL6
T677	140-145	P04141	denotes	GMCSF

Id	Subject	Object	Predicate	Lexical cue
T51	7-11	Protein	denotes	CD86
T52	33-40	Protein	denotes	SHARPIN
T53	41-50	Negative_regulation	denotes	deficient
T54	60-67	Negative_regulation	denotes	reduced
T55	68-81	Transcription	denotes	transcription
T56	126-129	Protein	denotes	IL6
T57	140-145	Protein	denotes	GMCSF
R25	T52	T53	themeOf	SHARPIN,deficient
R26	T53	T54	causeOf	deficient,reduced
R27	T55	T54	themeOf	transcription,reduced
R28	T56	T55	themeOf	IL6,transcription
R29	T57	T55	themeOf	GMCSF,transcription