PMC:3245220 / 9044-10073
Annnotations
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T23146 | 44-49 | P09603 | denotes | M-CSF |
T23147 | 46-49 | P04141 | denotes | CSF |
T23148 | 171-176 | P09603 | denotes | M-CSF |
T23149 | 173-176 | P04141 | denotes | CSF |
T23150 | 432-437 | P09603 | denotes | M-CSF |
T23151 | 434-437 | P04141 | denotes | CSF |
T23152 | 885-890 | P09603 | denotes | M-CSF |
T23153 | 887-890 | P04141 | denotes | CSF |
bionlp-st-ge-2016-reference
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T23154 | 44-49 | Protein | denotes | M-CSF |
T23155 | 171-176 | Protein | denotes | M-CSF |
T23156 | 432-437 | Protein | denotes | M-CSF |
T23157 | 885-890 | Protein | denotes | M-CSF |
bionlp-st-ge-2016-reference-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T23195 | 44-49 | Protein | denotes | M-CSF |
T23196 | 58-63 | Protein | denotes | NF-κB |
T23197 | 50-57 | Positive_regulation | denotes | induces |
T23198 | 171-176 | Protein | denotes | M-CSF |
T23199 | 199-204 | Protein | denotes | NF-κB |
T23200 | 209-216 | Binding | denotes | binding |
T23201 | 391-413 | Protein | denotes | pNF-κB-SEAP constructs |
T23202 | 432-437 | Protein | denotes | M-CSF |
T23203 | 514-519 | Protein | denotes | NF-κB |
T23204 | 569-573 | Protein | denotes | SEAP |
T23205 | 642-646 | Protein | denotes | SEAP |
T23206 | 574-582 | Localization | denotes | secreted |
T23207 | 574-582 | Localization | denotes | secreted |
T23208 | 630-638 | Positive_regulation | denotes | increase |
T23209 | 773-776 | Protein | denotes | pNF |
T23210 | 777-779 | Protein | denotes | κB |
T23211 | 780-784 | Protein | denotes | SEAP |
T23212 | 867-890 | Protein | denotes | mouse recombinant M-CSF |
R17695 | T23195 | T23197 | causeOf | M-CSF,induces |
R17696 | T23196 | T23197 | themeOf | NF-κB,induces |
R17697 | T23199 | T23200 | themeOf | NF-κB,binding |
R17698 | T23203 | T23206 | themeOf | NF-κB,secreted |
R17699 | T23204 | T23207 | themeOf | SEAP,secreted |
R17700 | T23205 | T23208 | themeOf | SEAP,increase |
events-check-again
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T23191 | 44-49 | Protein | denotes | M-CSF |
T23192 | 171-176 | Protein | denotes | M-CSF |
T23193 | 432-437 | Protein | denotes | M-CSF |
T23194 | 885-890 | Protein | denotes | M-CSF |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T23169 | 699-704 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T23170 | 720-725 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T23167 | 205-216 | http://purl.obolibrary.org/obo/GO_0003677 | denotes | DNA binding |
T23168 | 209-216 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T23166 | 64-79 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcriptional |
UBERON-AE
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T22809 | 807-812 | http://purl.obolibrary.org/obo/UBERON_0001977 | denotes | serum |
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T22987 | 44-49 | NN | denotes | M-CSF |
T22988 | 50-57 | VB | denotes | induces |
T22989 | 58-63 | NN | denotes | NF-κB |
T22990 | 64-79 | JJ | denotes | transcriptional |
T22991 | 80-88 | NN | denotes | activity |
T22992 | 89-91 | IN | denotes | in |
T22993 | 92-103 | NN | denotes | macrophages |
T22994 | 105-106 | -LRB- | denotes | ( |
T22995 | 106-107 | NN | denotes | A |
T22996 | 107-108 | -RRB- | denotes | ) |
T22997 | 109-115 | NN | denotes | Nuclei |
T22998 | 116-120 | VB | denotes | were |
T22999 | 121-130 | VB | denotes | extracted |
T23000 | 131-135 | IN | denotes | from |
T23001 | 136-141 | JJ | denotes | human |
T23002 | 142-146 | NN | denotes | MDMs |
T23003 | 147-154 | VB | denotes | treated |
T23004 | 155-162 | IN | denotes | without |
T23005 | 163-165 | CC | denotes | or |
T23006 | 166-170 | IN | denotes | with |
T23007 | 171-176 | NN | denotes | M-CSF |
T23008 | 177-180 | IN | denotes | for |
T23009 | 181-183 | CD | denotes | 15 |
T23010 | 184-186 | CC | denotes | or |
T23011 | 187-189 | CD | denotes | 30 |
T23012 | 190-197 | NN | denotes | minutes |
T23013 | 199-204 | NN | denotes | NF-κB |
T23014 | 205-208 | NN | denotes | DNA |
T23015 | 209-216 | NN | denotes | binding |
T23016 | 217-225 | NN | denotes | activity |
T23017 | 226-229 | VB | denotes | was |
T23018 | 230-238 | VB | denotes | analyzed |
T23019 | 239-241 | IN | denotes | by |
T23020 | 242-246 | NNP | denotes | EMSA |
T23021 | 247-252 | NNP | denotes | Shown |
T23022 | 253-255 | VB | denotes | is |
T23023 | 256-257 | DT | denotes | a |
T23024 | 258-272 | JJ | denotes | representative |
T23025 | 273-277 | NN | denotes | blot |
T23026 | 278-282 | IN | denotes | from |
T23027 | 283-288 | CD | denotes | three |
T23028 | 289-300 | JJ | denotes | independent |
T23029 | 301-312 | NN | denotes | experiments |
T23030 | 314-316 | NN | denotes | NS |
T23031 | 316-317 | -COLON- | denotes | : |
T23032 | 318-333 | JJ | denotes | non-stimulated. |
T23033 | 334-335 | -LRB- | denotes | ( |
T23034 | 335-336 | NN | denotes | B |
T23035 | 336-337 | -RRB- | denotes | ) |
T23036 | 338-343 | JJ | denotes | Human |
T23037 | 344-348 | NN | denotes | MDMs |
T23038 | 349-360 | RB | denotes | transiently |
T23039 | 361-372 | VB | denotes | transfected |
T23040 | 373-377 | IN | denotes | with |
T23041 | 378-387 | NN | denotes | pTAL-SEAP |
T23042 | 388-390 | CC | denotes | or |
T23043 | 391-402 | NN | denotes | pNF-κB-SEAP |
T23044 | 403-413 | NN | denotes | constructs |
T23045 | 414-418 | VB | denotes | were |
T23046 | 419-426 | VB | denotes | treated |
T23047 | 427-431 | IN | denotes | with |
T23048 | 432-437 | NN | denotes | M-CSF |
T23049 | 438-440 | IN | denotes | in |
T23050 | 441-447 | JJ | denotes | X-vivo |
T23051 | 448-454 | NN | denotes | medium |
T23052 | 455-458 | CC | denotes | and |
T23053 | 459-468 | VB | denotes | incubated |
T23054 | 469-472 | IN | denotes | for |
T23055 | 473-474 | CD | denotes | 6 |
T23056 | 475-480 | NN | denotes | hours |
T23057 | 481-487 | IN | denotes | before |
T23058 | 488-491 | DT | denotes | the |
T23059 | 492-502 | NN | denotes | collection |
T23060 | 503-505 | IN | denotes | of |
T23061 | 506-512 | NN | denotes | medium |
T23062 | 514-519 | NN | denotes | NF-κB |
T23063 | 520-528 | NN | denotes | activity |
T23064 | 529-532 | VB | denotes | was |
T23065 | 533-541 | VB | denotes | analyzed |
T23066 | 542-544 | IN | denotes | by |
T23067 | 545-554 | VB | denotes | measuring |
T23068 | 555-558 | DT | denotes | the |
T23069 | 559-565 | NN | denotes | amount |
T23070 | 566-568 | IN | denotes | of |
T23071 | 569-573 | NN | denotes | SEAP |
T23072 | 574-582 | VB | denotes | secreted |
T23073 | 583-587 | IN | denotes | into |
T23074 | 588-591 | DT | denotes | the |
T23075 | 592-598 | NN | denotes | medium |
T23076 | 599-602 | CC | denotes | and |
T23077 | 603-607 | NN | denotes | data |
T23078 | 608-611 | VB | denotes | are |
T23079 | 612-621 | VB | denotes | expressed |
T23080 | 622-624 | IN | denotes | as |
T23081 | 625-629 | JJ | denotes | fold |
T23082 | 630-638 | NN | denotes | increase |
T23083 | 639-641 | IN | denotes | of |
T23084 | 642-646 | NN | denotes | SEAP |
T23085 | 647-655 | NN | denotes | activity |
T23086 | 656-660 | IN | denotes | over |
T23087 | 661-665 | DT | denotes | that |
T23088 | 666-668 | IN | denotes | in |
T23089 | 669-678 | NN | denotes | pTAL-SEAP |
T23090 | 679-690 | VB | denotes | transfected |
T23091 | 691-698 | VB | denotes | resting |
T23092 | 699-705 | NN | denotes | cells. |
T23093 | 706-707 | -LRB- | denotes | ( |
T23094 | 707-708 | NN | denotes | C |
T23095 | 708-709 | -RRB- | denotes | ) |
T23096 | 710-713 | NN | denotes | RAW |
T23097 | 714-719 | CD | denotes | 264.7 |
T23098 | 720-725 | NN | denotes | cells |
T23099 | 726-730 | VB | denotes | were |
T23100 | 731-742 | RB | denotes | transiently |
T23101 | 743-754 | VB | denotes | transfected |
T23102 | 755-759 | IN | denotes | with |
T23103 | 760-769 | NN | denotes | pTAL-SEAP |
T23104 | 770-772 | CC | denotes | or |
T23105 | 773-784 | NN | denotes | pNF-κB-SEAP |
T23106 | 785-794 | NN | denotes | construct |
T23107 | 796-801 | NN | denotes | Cells |
T23108 | 802-806 | VB | denotes | were |
T23109 | 807-812 | NN | denotes | serum |
T23110 | 813-820 | VB | denotes | starved |
T23111 | 821-824 | IN | denotes | for |
T23112 | 825-826 | CD | denotes | 4 |
T23113 | 827-832 | NN | denotes | hours |
T23114 | 833-838 | RB | denotes | prior |
T23115 | 839-841 | TO | denotes | to |
T23116 | 842-843 | CD | denotes | 2 |
T23117 | 844-849 | NN | denotes | hours |
T23118 | 850-861 | NN | denotes | stimulation |
T23119 | 862-866 | IN | denotes | with |
T23120 | 867-872 | NN | denotes | mouse |
T23121 | 873-884 | JJ | denotes | recombinant |
T23122 | 885-890 | NN | denotes | M-CSF |
T23123 | 891-892 | -LRB- | denotes | ( |
T23124 | 892-895 | CD | denotes | 100 |
T23125 | 896-901 | NN | denotes | ng/ml |
T23126 | 901-902 | -RRB- | denotes | ) |
T23127 | 904-911 | NN | denotes | Culture |
T23128 | 912-917 | NN | denotes | media |
T23129 | 918-921 | VB | denotes | was |
T23130 | 922-931 | VB | denotes | collected |
T23131 | 932-934 | TO | denotes | to |
T23132 | 935-942 | VB | denotes | measure |
T23133 | 943-947 | NN | denotes | SEAP |
T23134 | 948-958 | NN | denotes | production |
T23135 | 960-964 | NN | denotes | Data |
T23136 | 965-968 | VB | denotes | are |
T23137 | 969-978 | VB | denotes | expressed |
T23138 | 979-983 | JJ | denotes | mean |
T23139 | 984-985 | JJ | denotes | ± |
T23140 | 986-991 | NN | denotes | S.E.M |
T23141 | 991-992 | -COMMA- | denotes | , |
T23142 | 993-996 | IN | denotes | for |
T23143 | 997-1002 | CD | denotes | three |
T23144 | 1003-1014 | JJ | denotes | independent |
T23145 | 1015-1026 | NN | denotes | experiments |
R17531 | T22987 | T22988 | arg1Of | M-CSF,induces |
R17532 | T22988 | T22992 | arg1Of | induces,in |
R17533 | T22991 | T22988 | arg2Of | activity,induces |
R17534 | T22991 | T22989 | arg1Of | activity,NF-κB |
R17535 | T22991 | T22990 | arg1Of | activity,transcriptional |
R17536 | T22993 | T22992 | arg2Of | macrophages,in |
R17537 | T22995 | T22994 | arg2Of | A,( |
R17538 | T22996 | T22994 | arg3Of | ),( |
R17539 | T22997 | T22994 | arg1Of | Nuclei,( |
R17540 | T22997 | T22998 | arg1Of | Nuclei,were |
R17541 | T22997 | T22999 | arg2Of | Nuclei,extracted |
R17542 | T22999 | T22998 | arg2Of | extracted,were |
R17543 | T22999 | T23000 | arg1Of | extracted,from |
R17544 | T23002 | T23000 | arg2Of | MDMs,from |
R17545 | T23002 | T23001 | arg1Of | MDMs,human |
R17546 | T23002 | T23003 | arg2Of | MDMs,treated |
R17547 | T23003 | T23004 | arg1Of | treated,without |
R17548 | T23003 | T23006 | arg1Of | treated,with |
R17549 | T23004 | T23005 | arg1Of | without,or |
R17550 | T23006 | T23005 | arg2Of | with,or |
R17551 | T23007 | T23004 | arg2Of | M-CSF,without |
R17552 | T23007 | T23006 | arg2Of | M-CSF,with |
R17553 | T23007 | T23008 | arg1Of | M-CSF,for |
R17554 | T23009 | T23010 | arg1Of | 15,or |
R17555 | T23011 | T23010 | arg2Of | 30,or |
R17556 | T23012 | T23008 | arg2Of | minutes,for |
R17557 | T23012 | T23009 | arg1Of | minutes,15 |
R17558 | T23012 | T23011 | arg1Of | minutes,30 |
R17559 | T23013 | T23022 | arg1Of | NF-κB,is |
R17560 | T23016 | T23014 | arg1Of | activity,DNA |
R17561 | T23016 | T23015 | arg1Of | activity,binding |
R17562 | T23016 | T23017 | arg1Of | activity,was |
R17563 | T23016 | T23018 | arg2Of | activity,analyzed |
R17564 | T23018 | T23017 | arg2Of | analyzed,was |
R17565 | T23021 | T23018 | arg1Of | Shown,analyzed |
R17566 | T23021 | T23019 | arg2Of | Shown,by |
R17567 | T23021 | T23020 | arg1Of | Shown,EMSA |
R17568 | T23022 | T23017 | modOf | is,was |
R17569 | T23025 | T23022 | arg2Of | blot,is |
R17570 | T23025 | T23023 | arg1Of | blot,a |
R17571 | T23025 | T23024 | arg1Of | blot,representative |
R17572 | T23025 | T23026 | arg1Of | blot,from |
R17573 | T23029 | T23026 | arg2Of | experiments,from |
R17574 | T23029 | T23027 | arg1Of | experiments,three |
R17575 | T23029 | T23028 | arg1Of | experiments,independent |
R17576 | T23030 | T23031 | arg1Of | NS,: |
R17577 | T23030 | T23045 | modOf | NS,were |
R17578 | T23034 | T23033 | arg2Of | B,( |
R17579 | T23035 | T23033 | arg3Of | ),( |
R17580 | T23037 | T23032 | arg1Of | MDMs,non-stimulated. |
R17581 | T23037 | T23033 | arg1Of | MDMs,( |
R17582 | T23037 | T23036 | arg1Of | MDMs,Human |
R17583 | T23037 | T23039 | arg2Of | MDMs,transfected |
R17584 | T23037 | T23045 | arg1Of | MDMs,were |
R17585 | T23037 | T23046 | arg2Of | MDMs,treated |
R17586 | T23037 | T23053 | arg2Of | MDMs,incubated |
R17587 | T23039 | T23038 | arg1Of | transfected,transiently |
R17588 | T23039 | T23040 | arg1Of | transfected,with |
R17589 | T23041 | T23042 | arg1Of | pTAL-SEAP,or |
R17590 | T23043 | T23042 | arg2Of | pNF-κB-SEAP,or |
R17591 | T23044 | T23040 | arg2Of | constructs,with |
R17592 | T23044 | T23041 | arg1Of | constructs,pTAL-SEAP |
R17593 | T23044 | T23043 | arg1Of | constructs,pNF-κB-SEAP |
R17594 | T23046 | T23047 | arg1Of | treated,with |
R17595 | T23046 | T23052 | arg1Of | treated,and |
R17596 | T23048 | T23047 | arg2Of | M-CSF,with |
R17597 | T23048 | T23049 | arg1Of | M-CSF,in |
R17598 | T23051 | T23049 | arg2Of | medium,in |
R17599 | T23051 | T23050 | arg1Of | medium,X-vivo |
R17600 | T23052 | T23045 | arg2Of | and,were |
R17601 | T23053 | T23052 | arg2Of | incubated,and |
R17602 | T23053 | T23054 | arg1Of | incubated,for |
R17603 | T23053 | T23057 | arg1Of | incubated,before |
R17604 | T23056 | T23054 | arg2Of | hours,for |
R17605 | T23056 | T23055 | arg1Of | hours,6 |
R17606 | T23059 | T23057 | arg2Of | collection,before |
R17607 | T23059 | T23058 | arg1Of | collection,the |
R17608 | T23059 | T23060 | arg1Of | collection,of |
R17609 | T23061 | T23060 | arg2Of | medium,of |
R17610 | T23063 | T23062 | arg1Of | activity,NF-κB |
R17611 | T23063 | T23064 | arg1Of | activity,was |
R17612 | T23063 | T23065 | arg2Of | activity,analyzed |
R17613 | T23065 | T23064 | arg2Of | analyzed,was |
R17614 | T23065 | T23066 | arg1Of | analyzed,by |
R17615 | T23065 | T23076 | arg1Of | analyzed,and |
R17616 | T23067 | T23066 | arg2Of | measuring,by |
R17617 | T23069 | T23067 | arg2Of | amount,measuring |
R17618 | T23069 | T23068 | arg1Of | amount,the |
R17619 | T23069 | T23070 | arg1Of | amount,of |
R17620 | T23069 | T23072 | arg2Of | amount,secreted |
R17621 | T23071 | T23070 | arg2Of | SEAP,of |
R17622 | T23072 | T23073 | arg1Of | secreted,into |
R17623 | T23075 | T23073 | arg2Of | medium,into |
R17624 | T23075 | T23074 | arg1Of | medium,the |
R17625 | T23077 | T23078 | arg1Of | data,are |
R17626 | T23077 | T23079 | arg2Of | data,expressed |
R17627 | T23079 | T23076 | arg2Of | expressed,and |
R17628 | T23079 | T23078 | arg2Of | expressed,are |
R17629 | T23079 | T23080 | arg1Of | expressed,as |
R17630 | T23082 | T23083 | arg1Of | increase,of |
R17631 | T23082 | T23086 | arg1Of | increase,over |
R17632 | T23085 | T23083 | arg2Of | activity,of |
R17633 | T23085 | T23084 | arg1Of | activity,SEAP |
R17634 | T23087 | T23086 | arg2Of | that,over |
R17635 | T23087 | T23088 | arg1Of | that,in |
R17636 | T23092 | T23088 | arg2Of | cells.,in |
R17637 | T23092 | T23089 | arg1Of | cells.,pTAL-SEAP |
R17638 | T23092 | T23090 | arg2Of | cells.,transfected |
R17639 | T23092 | T23091 | arg1Of | cells.,resting |
R17640 | T23092 | T23093 | arg1Of | cells.,( |
R17641 | T23094 | T23093 | arg2Of | C,( |
R17642 | T23095 | T23093 | arg3Of | ),( |
R17643 | T23098 | T23081 | arg1Of | cells,fold |
R17644 | T23098 | T23082 | arg1Of | cells,increase |
R17645 | T23098 | T23096 | arg1Of | cells,RAW |
R17646 | T23098 | T23097 | arg1Of | cells,264.7 |
R17647 | T23098 | T23099 | arg1Of | cells,were |
R17648 | T23098 | T23101 | arg2Of | cells,transfected |
R17649 | T23101 | T23080 | arg2Of | transfected,as |
R17650 | T23101 | T23099 | arg2Of | transfected,were |
R17651 | T23101 | T23100 | arg1Of | transfected,transiently |
R17652 | T23101 | T23102 | arg1Of | transfected,with |
R17653 | T23103 | T23104 | arg1Of | pTAL-SEAP,or |
R17654 | T23104 | T23102 | arg2Of | or,with |
R17655 | T23106 | T23104 | arg2Of | construct,or |
R17656 | T23106 | T23105 | arg1Of | construct,pNF-κB-SEAP |
R17657 | T23107 | T23108 | arg1Of | Cells,were |
R17658 | T23109 | T23108 | arg2Of | serum,were |
R17659 | T23109 | T23110 | arg2Of | serum,starved |
R17660 | T23110 | T23111 | arg1Of | starved,for |
R17661 | T23112 | T23115 | arg1Of | 4,to |
R17662 | T23114 | T23113 | arg1Of | prior,hours |
R17663 | T23115 | T23114 | arg1Of | to,prior |
R17664 | T23117 | T23115 | arg2Of | hours,to |
R17665 | T23117 | T23116 | arg1Of | hours,2 |
R17666 | T23118 | T23111 | arg2Of | stimulation,for |
R17667 | T23118 | T23112 | arg1Of | stimulation,4 |
R17668 | T23118 | T23119 | arg1Of | stimulation,with |
R17669 | T23122 | T23119 | arg2Of | M-CSF,with |
R17670 | T23122 | T23120 | arg1Of | M-CSF,mouse |
R17671 | T23122 | T23121 | arg1Of | M-CSF,recombinant |
R17672 | T23122 | T23123 | arg1Of | M-CSF,( |
R17673 | T23125 | T23123 | arg2Of | ng/ml,( |
R17674 | T23125 | T23124 | arg1Of | ng/ml,100 |
R17675 | T23126 | T23123 | arg3Of | ),( |
R17676 | T23128 | T23127 | arg1Of | media,Culture |
R17677 | T23128 | T23129 | arg1Of | media,was |
R17678 | T23128 | T23130 | arg2Of | media,collected |
R17679 | T23130 | T23129 | arg2Of | collected,was |
R17680 | T23130 | T23131 | modOf | collected,to |
R17681 | T23132 | T23131 | arg1Of | measure,to |
R17682 | T23134 | T23132 | arg2Of | production,measure |
R17683 | T23134 | T23133 | arg1Of | production,SEAP |
R17684 | T23135 | T23136 | arg1Of | Data,are |
R17685 | T23135 | T23137 | arg2Of | Data,expressed |
R17686 | T23137 | T23136 | arg2Of | expressed,are |
R17687 | T23137 | T23140 | arg1Of | expressed,S.E.M |
R17688 | T23137 | T23141 | arg1Of | expressed,"," |
R17689 | T23137 | T23142 | arg1Of | expressed,for |
R17690 | T23140 | T23138 | arg1Of | S.E.M,mean |
R17691 | T23140 | T23139 | arg1Of | S.E.M,± |
R17692 | T23145 | T23142 | arg2Of | experiments,for |
R17693 | T23145 | T23143 | arg1Of | experiments,three |
R17694 | T23145 | T23144 | arg1Of | experiments,independent |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T22810 | 44-104 | Sentence | denotes | M-CSF induces NF-κB transcriptional activity in macrophages. |
T22811 | 105-198 | Sentence | denotes | (A) Nuclei were extracted from human MDMs treated without or with M-CSF for 15 or 30 minutes. |
T22812 | 199-313 | Sentence | denotes | NF-κB DNA binding activity was analyzed by EMSA Shown is a representative blot from three independent experiments. |
T22813 | 314-513 | Sentence | denotes | NS: non-stimulated. (B) Human MDMs transiently transfected with pTAL-SEAP or pNF-κB-SEAP constructs were treated with M-CSF in X-vivo medium and incubated for 6 hours before the collection of medium. |
T22814 | 514-795 | Sentence | denotes | NF-κB activity was analyzed by measuring the amount of SEAP secreted into the medium and data are expressed as fold increase of SEAP activity over that in pTAL-SEAP transfected resting cells. (C) RAW 264.7 cells were transiently transfected with pTAL-SEAP or pNF-κB-SEAP construct. |
T22815 | 796-903 | Sentence | denotes | Cells were serum starved for 4 hours prior to 2 hours stimulation with mouse recombinant M-CSF (100 ng/ml). |
T22816 | 904-959 | Sentence | denotes | Culture media was collected to measure SEAP production. |
T22817 | 960-1027 | Sentence | denotes | Data are expressed mean ± S.E.M, for three independent experiments. |
T68 | 0-104 | Sentence | denotes | 10.1371/journal.pone.0028081.g001 Figure 1 M-CSF induces NF-κB transcriptional activity in macrophages. |
T69 | 105-198 | Sentence | denotes | (A) Nuclei were extracted from human MDMs treated without or with M-CSF for 15 or 30 minutes. |
T70 | 199-313 | Sentence | denotes | NF-κB DNA binding activity was analyzed by EMSA Shown is a representative blot from three independent experiments. |
T71 | 314-513 | Sentence | denotes | NS: non-stimulated. (B) Human MDMs transiently transfected with pTAL-SEAP or pNF-κB-SEAP constructs were treated with M-CSF in X-vivo medium and incubated for 6 hours before the collection of medium. |
T72 | 514-795 | Sentence | denotes | NF-κB activity was analyzed by measuring the amount of SEAP secreted into the medium and data are expressed as fold increase of SEAP activity over that in pTAL-SEAP transfected resting cells. (C) RAW 264.7 cells were transiently transfected with pTAL-SEAP or pNF-κB-SEAP construct. |
T73 | 796-903 | Sentence | denotes | Cells were serum starved for 4 hours prior to 2 hours stimulation with mouse recombinant M-CSF (100 ng/ml). |
T74 | 904-959 | Sentence | denotes | Culture media was collected to measure SEAP production. |
T75 | 960-1027 | Sentence | denotes | Data are expressed mean ± S.E.M, for three independent experiments. |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T22818 | 44-49 | NNP | denotes | M-CSF |
T22819 | 50-57 | VBZ | denotes | induces |
T22820 | 58-63 | JJ | denotes | NF-κB |
T22821 | 64-79 | JJ | denotes | transcriptional |
T22822 | 80-88 | NN | denotes | activity |
T22823 | 89-91 | IN | denotes | in |
T22824 | 92-103 | NNS | denotes | macrophages |
T22825 | 103-104 | . | denotes | . |
T22826 | 105-106 | -LRB- | denotes | ( |
T22827 | 106-107 | NNP | denotes | A |
T22828 | 107-108 | -RRB- | denotes | ) |
T22829 | 109-115 | NNP | denotes | Nuclei |
T22830 | 116-120 | VBD | denotes | were |
T22831 | 121-130 | VBN | denotes | extracted |
T22832 | 131-135 | IN | denotes | from |
T22833 | 136-141 | JJ | denotes | human |
T22834 | 142-146 | NNS | denotes | MDMs |
T22835 | 147-154 | VBN | denotes | treated |
T22836 | 155-162 | IN | denotes | without |
T22837 | 163-165 | CC | denotes | or |
T22838 | 166-170 | IN | denotes | with |
T22839 | 171-176 | NNP | denotes | M-CSF |
T22840 | 177-180 | IN | denotes | for |
T22841 | 181-183 | CD | denotes | 15 |
T22842 | 184-186 | CC | denotes | or |
T22843 | 187-189 | CD | denotes | 30 |
T22844 | 190-197 | NNS | denotes | minutes |
T22845 | 197-198 | . | denotes | . |
T22846 | 199-204 | NNP | denotes | NF-κB |
T22847 | 205-208 | NNP | denotes | DNA |
T22848 | 209-216 | JJ | denotes | binding |
T22849 | 217-225 | NN | denotes | activity |
T22850 | 226-229 | VBD | denotes | was |
T22851 | 230-238 | VBN | denotes | analyzed |
T22852 | 239-241 | IN | denotes | by |
T22853 | 242-246 | NNP | denotes | EMSA |
T22854 | 247-252 | NNP | denotes | Shown |
T22855 | 253-255 | VBZ | denotes | is |
T22856 | 256-257 | DT | denotes | a |
T22857 | 258-272 | JJ | denotes | representative |
T22858 | 273-277 | NN | denotes | blot |
T22859 | 278-282 | IN | denotes | from |
T22860 | 283-288 | CD | denotes | three |
T22861 | 289-300 | JJ | denotes | independent |
T22862 | 301-312 | NNS | denotes | experiments |
T22863 | 312-313 | . | denotes | . |
T22864 | 314-316 | NNP | denotes | NS |
T22865 | 316-317 | : | denotes | : |
T22866 | 318-332 | JJ | denotes | non-stimulated |
T22867 | 332-333 | . | denotes | . |
T22868 | 334-335 | -LRB- | denotes | ( |
T22869 | 335-336 | NNP | denotes | B |
T22870 | 336-337 | -RRB- | denotes | ) |
T22871 | 338-343 | NNP | denotes | Human |
T22872 | 344-348 | NNP | denotes | MDMs |
T22873 | 349-360 | RB | denotes | transiently |
T22874 | 361-372 | VBD | denotes | transfected |
T22875 | 373-377 | IN | denotes | with |
T22876 | 378-387 | JJ | denotes | pTAL-SEAP |
T22877 | 388-390 | CC | denotes | or |
T22878 | 391-402 | JJ | denotes | pNF-κB-SEAP |
T22879 | 403-413 | NNS | denotes | constructs |
T22880 | 414-418 | VBD | denotes | were |
T22881 | 419-426 | VBN | denotes | treated |
T22882 | 427-431 | IN | denotes | with |
T22883 | 432-437 | NNP | denotes | M-CSF |
T22884 | 438-440 | IN | denotes | in |
T22885 | 441-447 | NNP | denotes | X-vivo |
T22886 | 448-454 | NN | denotes | medium |
T22887 | 455-458 | CC | denotes | and |
T22888 | 459-468 | VBN | denotes | incubated |
T22889 | 469-472 | IN | denotes | for |
T22890 | 473-474 | CD | denotes | 6 |
T22891 | 475-480 | NNS | denotes | hours |
T22892 | 481-487 | IN | denotes | before |
T22893 | 488-491 | DT | denotes | the |
T22894 | 492-502 | NN | denotes | collection |
T22895 | 503-505 | IN | denotes | of |
T22896 | 506-512 | NN | denotes | medium |
T22897 | 512-513 | . | denotes | . |
T22898 | 514-519 | JJ | denotes | NF-κB |
T22899 | 520-528 | NN | denotes | activity |
T22900 | 529-532 | VBD | denotes | was |
T22901 | 533-541 | VBN | denotes | analyzed |
T22902 | 542-544 | IN | denotes | by |
T22903 | 545-554 | VBG | denotes | measuring |
T22904 | 555-558 | DT | denotes | the |
T22905 | 559-565 | NN | denotes | amount |
T22906 | 566-568 | IN | denotes | of |
T22907 | 569-573 | NNP | denotes | SEAP |
T22908 | 574-582 | VBD | denotes | secreted |
T22909 | 583-587 | IN | denotes | into |
T22910 | 588-591 | DT | denotes | the |
T22911 | 592-598 | NN | denotes | medium |
T22912 | 599-602 | CC | denotes | and |
T22913 | 603-607 | NNS | denotes | data |
T22914 | 608-611 | VBP | denotes | are |
T22915 | 612-621 | VBN | denotes | expressed |
T22916 | 622-624 | IN | denotes | as |
T22917 | 625-629 | VBP | denotes | fold |
T22918 | 630-638 | NN | denotes | increase |
T22919 | 639-641 | IN | denotes | of |
T22920 | 642-646 | NNP | denotes | SEAP |
T22921 | 647-655 | NN | denotes | activity |
T22922 | 656-660 | IN | denotes | over |
T22923 | 661-665 | DT | denotes | that |
T22924 | 666-668 | IN | denotes | in |
T22925 | 669-678 | JJ | denotes | pTAL-SEAP |
T22926 | 679-690 | VBN | denotes | transfected |
T22927 | 691-698 | VBG | denotes | resting |
T22928 | 699-704 | NNS | denotes | cells |
T22929 | 704-705 | . | denotes | . |
T22930 | 706-707 | -LRB- | denotes | ( |
T22931 | 707-708 | NNP | denotes | C |
T22932 | 708-709 | -RRB- | denotes | ) |
T22933 | 710-713 | NNP | denotes | RAW |
T22934 | 714-719 | CD | denotes | 264.7 |
T22935 | 720-725 | NNS | denotes | cells |
T22936 | 726-730 | VBD | denotes | were |
T22937 | 731-742 | RB | denotes | transiently |
T22938 | 743-754 | VBN | denotes | transfected |
T22939 | 755-759 | IN | denotes | with |
T22940 | 760-769 | NNP | denotes | pTAL-SEAP |
T22941 | 770-772 | CC | denotes | or |
T22942 | 773-784 | NNP | denotes | pNF-κB-SEAP |
T22943 | 785-794 | VBP | denotes | construct |
T22944 | 794-795 | . | denotes | . |
T22945 | 796-801 | NNS | denotes | Cells |
T22946 | 802-806 | VBD | denotes | were |
T22947 | 807-812 | JJ | denotes | serum |
T22948 | 813-820 | VBN | denotes | starved |
T22949 | 821-824 | IN | denotes | for |
T22950 | 825-826 | CD | denotes | 4 |
T22951 | 827-832 | NNS | denotes | hours |
T22952 | 833-838 | RB | denotes | prior |
T22953 | 839-841 | TO | denotes | to |
T22954 | 842-843 | CD | denotes | 2 |
T22955 | 844-849 | NNS | denotes | hours |
T22956 | 850-861 | NN | denotes | stimulation |
T22957 | 862-866 | IN | denotes | with |
T22958 | 867-872 | NN | denotes | mouse |
T22959 | 873-884 | JJ | denotes | recombinant |
T22960 | 885-890 | NNP | denotes | M-CSF |
T22961 | 891-892 | -LRB- | denotes | ( |
T22962 | 892-895 | CD | denotes | 100 |
T22963 | 896-901 | NN | denotes | ng/ml |
T22964 | 901-902 | -RRB- | denotes | ) |
T22965 | 902-903 | . | denotes | . |
T22966 | 904-911 | NNP | denotes | Culture |
T22967 | 912-917 | NNS | denotes | media |
T22968 | 918-921 | VBD | denotes | was |
T22969 | 922-931 | VBN | denotes | collected |
T22970 | 932-934 | TO | denotes | to |
T22971 | 935-942 | VB | denotes | measure |
T22972 | 943-947 | NNP | denotes | SEAP |
T22973 | 948-958 | NN | denotes | production |
T22974 | 958-959 | . | denotes | . |
T22975 | 960-964 | NNS | denotes | Data |
T22976 | 965-968 | VBP | denotes | are |
T22977 | 969-978 | VBN | denotes | expressed |
T22978 | 979-983 | JJ | denotes | mean |
T22979 | 984-985 | NN | denotes | ± |
T22980 | 986-991 | NNP | denotes | S.E.M |
T22981 | 991-992 | , | denotes | , |
T22982 | 993-996 | IN | denotes | for |
T22983 | 997-1002 | CD | denotes | three |
T22984 | 1003-1014 | JJ | denotes | independent |
T22985 | 1015-1026 | NNS | denotes | experiments |
T22986 | 1026-1027 | . | denotes | . |
R17362 | T22818 | T22819 | nsubj | M-CSF,induces |
R17363 | T22819 | T22819 | ROOT | induces,induces |
R17364 | T22820 | T22822 | amod | NF-κB,activity |
R17365 | T22821 | T22822 | amod | transcriptional,activity |
R17366 | T22822 | T22819 | dobj | activity,induces |
R17367 | T22823 | T22822 | prep | in,activity |
R17368 | T22824 | T22823 | pobj | macrophages,in |
R17369 | T22825 | T22819 | punct | .,induces |
R17370 | T22826 | T22831 | punct | (,extracted |
R17371 | T22827 | T22829 | nmod | A,Nuclei |
R17372 | T22828 | T22827 | punct | ),A |
R17373 | T22829 | T22831 | nsubjpass | Nuclei,extracted |
R17374 | T22830 | T22831 | auxpass | were,extracted |
R17375 | T22831 | T22831 | ROOT | extracted,extracted |
R17376 | T22832 | T22831 | prep | from,extracted |
R17377 | T22833 | T22834 | amod | human,MDMs |
R17378 | T22834 | T22832 | pobj | MDMs,from |
R17379 | T22835 | T22831 | conj | treated,extracted |
R17380 | T22836 | T22835 | prep | without,treated |
R17381 | T22837 | T22836 | cc | or,without |
R17382 | T22838 | T22836 | conj | with,without |
R17383 | T22839 | T22838 | pobj | M-CSF,with |
R17384 | T22840 | T22835 | prep | for,treated |
R17385 | T22841 | T22844 | nummod | 15,minutes |
R17386 | T22842 | T22841 | cc | or,15 |
R17387 | T22843 | T22841 | conj | 30,15 |
R17388 | T22844 | T22840 | pobj | minutes,for |
R17389 | T22845 | T22831 | punct | .,extracted |
R17390 | T22846 | T22847 | compound | NF-κB,DNA |
R17391 | T22847 | T22849 | compound | DNA,activity |
R17392 | T22848 | T22849 | amod | binding,activity |
R17393 | T22849 | T22851 | nsubjpass | activity,analyzed |
R17394 | T22850 | T22851 | auxpass | was,analyzed |
R17395 | T22851 | T22851 | ROOT | analyzed,analyzed |
R17396 | T22852 | T22851 | agent | by,analyzed |
R17397 | T22853 | T22854 | compound | EMSA,Shown |
R17398 | T22854 | T22852 | pobj | Shown,by |
R17399 | T22855 | T22851 | conj | is,analyzed |
R17400 | T22856 | T22858 | det | a,blot |
R17401 | T22857 | T22858 | amod | representative,blot |
R17402 | T22858 | T22855 | attr | blot,is |
R17403 | T22859 | T22858 | prep | from,blot |
R17404 | T22860 | T22862 | nummod | three,experiments |
R17405 | T22861 | T22862 | amod | independent,experiments |
R17406 | T22862 | T22859 | pobj | experiments,from |
R17407 | T22863 | T22851 | punct | .,analyzed |
R17408 | T22864 | T22864 | ROOT | NS,NS |
R17409 | T22865 | T22864 | punct | :,NS |
R17410 | T22866 | T22864 | acl | non-stimulated,NS |
R17411 | T22867 | T22864 | punct | .,NS |
R17412 | T22868 | T22874 | punct | (,transfected |
R17413 | T22869 | T22874 | dep | B,transfected |
R17414 | T22870 | T22869 | punct | ),B |
R17415 | T22871 | T22872 | compound | Human,MDMs |
R17416 | T22872 | T22874 | nsubj | MDMs,transfected |
R17417 | T22873 | T22874 | advmod | transiently,transfected |
R17418 | T22874 | T22874 | ROOT | transfected,transfected |
R17419 | T22875 | T22874 | prep | with,transfected |
R17420 | T22876 | T22879 | amod | pTAL-SEAP,constructs |
R17421 | T22877 | T22876 | cc | or,pTAL-SEAP |
R17422 | T22878 | T22876 | conj | pNF-κB-SEAP,pTAL-SEAP |
R17423 | T22879 | T22875 | pobj | constructs,with |
R17424 | T22880 | T22881 | auxpass | were,treated |
R17425 | T22881 | T22874 | dep | treated,transfected |
R17426 | T22882 | T22881 | prep | with,treated |
R17427 | T22883 | T22882 | pobj | M-CSF,with |
R17428 | T22884 | T22883 | prep | in,M-CSF |
R17429 | T22885 | T22886 | compound | X-vivo,medium |
R17430 | T22886 | T22884 | pobj | medium,in |
R17431 | T22887 | T22881 | cc | and,treated |
R17432 | T22888 | T22881 | conj | incubated,treated |
R17433 | T22889 | T22888 | prep | for,incubated |
R17434 | T22890 | T22891 | nummod | 6,hours |
R17435 | T22891 | T22889 | pobj | hours,for |
R17436 | T22892 | T22888 | advmod | before,incubated |
R17437 | T22893 | T22894 | det | the,collection |
R17438 | T22894 | T22892 | pobj | collection,before |
R17439 | T22895 | T22894 | prep | of,collection |
R17440 | T22896 | T22895 | pobj | medium,of |
R17441 | T22897 | T22874 | punct | .,transfected |
R17442 | T22898 | T22899 | amod | NF-κB,activity |
R17443 | T22899 | T22901 | nsubjpass | activity,analyzed |
R17444 | T22900 | T22901 | auxpass | was,analyzed |
R17445 | T22901 | T22901 | ROOT | analyzed,analyzed |
R17446 | T22902 | T22901 | prep | by,analyzed |
R17447 | T22903 | T22902 | pcomp | measuring,by |
R17448 | T22904 | T22905 | det | the,amount |
R17449 | T22905 | T22903 | dobj | amount,measuring |
R17450 | T22906 | T22905 | prep | of,amount |
R17451 | T22907 | T22906 | pobj | SEAP,of |
R17452 | T22908 | T22901 | conj | secreted,analyzed |
R17453 | T22909 | T22908 | prep | into,secreted |
R17454 | T22910 | T22911 | det | the,medium |
R17455 | T22911 | T22909 | pobj | medium,into |
R17456 | T22912 | T22911 | cc | and,medium |
R17457 | T22913 | T22911 | conj | data,medium |
R17458 | T22914 | T22915 | auxpass | are,expressed |
R17459 | T22915 | T22915 | ROOT | expressed,expressed |
R17460 | T22916 | T22915 | prep | as,expressed |
R17461 | T22917 | T22918 | compound | fold,increase |
R17462 | T22918 | T22916 | pobj | increase,as |
R17463 | T22919 | T22918 | prep | of,increase |
R17464 | T22920 | T22921 | compound | SEAP,activity |
R17465 | T22921 | T22919 | pobj | activity,of |
R17466 | T22922 | T22921 | prep | over,activity |
R17467 | T22923 | T22922 | pobj | that,over |
R17468 | T22924 | T22921 | prep | in,activity |
R17469 | T22925 | T22928 | amod | pTAL-SEAP,cells |
R17470 | T22926 | T22928 | amod | transfected,cells |
R17471 | T22927 | T22928 | amod | resting,cells |
R17472 | T22928 | T22924 | pobj | cells,in |
R17473 | T22929 | T22901 | punct | .,analyzed |
R17474 | T22930 | T22933 | punct | (,RAW |
R17475 | T22931 | T22933 | nmod | C,RAW |
R17476 | T22932 | T22933 | punct | ),RAW |
R17477 | T22933 | T22938 | nsubjpass | RAW,transfected |
R17478 | T22934 | T22935 | nummod | 264.7,cells |
R17479 | T22935 | T22938 | nsubjpass | cells,transfected |
R17480 | T22936 | T22938 | auxpass | were,transfected |
R17481 | T22937 | T22938 | advmod | transiently,transfected |
R17482 | T22938 | T22938 | ROOT | transfected,transfected |
R17483 | T22939 | T22938 | prep | with,transfected |
R17484 | T22940 | T22939 | pobj | pTAL-SEAP,with |
R17485 | T22941 | T22940 | cc | or,pTAL-SEAP |
R17486 | T22942 | T22940 | conj | pNF-κB-SEAP,pTAL-SEAP |
R17487 | T22943 | T22938 | conj | construct,transfected |
R17488 | T22944 | T22938 | punct | .,transfected |
R17489 | T22945 | T22948 | nsubjpass | Cells,starved |
R17490 | T22946 | T22948 | auxpass | were,starved |
R17491 | T22947 | T22948 | advmod | serum,starved |
R17492 | T22948 | T22948 | ROOT | starved,starved |
R17493 | T22949 | T22948 | prep | for,starved |
R17494 | T22950 | T22951 | nummod | 4,hours |
R17495 | T22951 | T22949 | pobj | hours,for |
R17496 | T22952 | T22948 | advmod | prior,starved |
R17497 | T22953 | T22952 | prep | to,prior |
R17498 | T22954 | T22955 | nummod | 2,hours |
R17499 | T22955 | T22953 | pobj | hours,to |
R17500 | T22956 | T22948 | advcl | stimulation,starved |
R17501 | T22957 | T22956 | prep | with,stimulation |
R17502 | T22958 | T22960 | amod | mouse,M-CSF |
R17503 | T22959 | T22960 | amod | recombinant,M-CSF |
R17504 | T22960 | T22957 | pobj | M-CSF,with |
R17505 | T22961 | T22963 | punct | (,ng/ml |
R17506 | T22962 | T22963 | nummod | 100,ng/ml |
R17507 | T22963 | T22960 | appos | ng/ml,M-CSF |
R17508 | T22964 | T22963 | punct | ),ng/ml |
R17509 | T22965 | T22948 | punct | .,starved |
R17510 | T22966 | T22967 | compound | Culture,media |
R17511 | T22967 | T22969 | nsubjpass | media,collected |
R17512 | T22968 | T22969 | auxpass | was,collected |
R17513 | T22969 | T22969 | ROOT | collected,collected |
R17514 | T22970 | T22971 | aux | to,measure |
R17515 | T22971 | T22969 | xcomp | measure,collected |
R17516 | T22972 | T22973 | compound | SEAP,production |
R17517 | T22973 | T22971 | dobj | production,measure |
R17518 | T22974 | T22969 | punct | .,collected |
R17519 | T22975 | T22977 | nsubjpass | Data,expressed |
R17520 | T22976 | T22977 | auxpass | are,expressed |
R17521 | T22977 | T22977 | ROOT | expressed,expressed |
R17522 | T22978 | T22980 | amod | mean,S.E.M |
R17523 | T22979 | T22980 | compound | ±,S.E.M |
R17524 | T22980 | T22977 | dobj | S.E.M,expressed |
R17525 | T22981 | T22977 | punct | ",",expressed |
R17526 | T22982 | T22977 | prep | for,expressed |
R17527 | T22983 | T22985 | nummod | three,experiments |
R17528 | T22984 | T22985 | amod | independent,experiments |
R17529 | T22985 | T22982 | pobj | experiments,for |
R17530 | T22986 | T22977 | punct | .,expressed |
test2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T22805 | 44-49 | Protein | denotes | M-CSF |
T22806 | 171-176 | Protein | denotes | M-CSF |
T22807 | 432-437 | Protein | denotes | M-CSF |
T22808 | 885-890 | Protein | denotes | M-CSF |