PMC:3245220 / 8087-10511
Annnotations
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5134 | 0-5 | P09603 | denotes | M-CSF |
T5135 | 2-5 | P04141 | denotes | CSF |
T5136 | 148-153 | P09603 | denotes | M-CSF |
T5137 | 150-153 | P04141 | denotes | CSF |
T5138 | 253-258 | P09603 | denotes | M-CSF |
T5139 | 255-258 | P04141 | denotes | CSF |
T5140 | 409-414 | P09603 | denotes | M-CSF |
T5141 | 411-414 | P04141 | denotes | CSF |
T5142 | 590-595 | P09603 | denotes | M-CSF |
T5143 | 592-595 | P04141 | denotes | CSF |
T5144 | 938-943 | P09603 | denotes | M-CSF |
T5145 | 940-943 | P04141 | denotes | CSF |
T5146 | 2016-2021 | P09603 | denotes | M-CSF |
T5147 | 2018-2021 | P04141 | denotes | CSF |
T5148 | 2215-2220 | P09603 | denotes | M-CSF |
T5149 | 2217-2220 | P04141 | denotes | CSF |
T5150 | 2364-2369 | P09603 | denotes | M-CSF |
T5151 | 2366-2369 | P04141 | denotes | CSF |
T23146 | 1001-1006 | P09603 | denotes | M-CSF |
T23147 | 1003-1006 | P04141 | denotes | CSF |
T23148 | 1128-1133 | P09603 | denotes | M-CSF |
T23149 | 1130-1133 | P04141 | denotes | CSF |
T23150 | 1389-1394 | P09603 | denotes | M-CSF |
T23151 | 1391-1394 | P04141 | denotes | CSF |
T23152 | 1842-1847 | P09603 | denotes | M-CSF |
T23153 | 1844-1847 | P04141 | denotes | CSF |
bionlp-st-ge-2016-reference
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5152 | 2250-2259 | Positive_regulation | denotes | increased |
T5153 | 2275-2283 | Positive_regulation | denotes | activity |
T5154 | 2260-2265 | Protein | denotes | NF-κB |
T5155 | 0-5 | Protein | denotes | M-CSF |
T5156 | 148-153 | Protein | denotes | M-CSF |
T5157 | 253-258 | Protein | denotes | M-CSF |
T5158 | 409-414 | Protein | denotes | M-CSF |
T5159 | 590-595 | Protein | denotes | M-CSF |
T5160 | 938-943 | Protein | denotes | M-CSF |
T5161 | 2016-2021 | Protein | denotes | M-CSF |
T5162 | 2215-2220 | Protein | denotes | M-CSF |
T5163 | 2364-2369 | Protein | denotes | M-CSF |
T23154 | 1001-1006 | Protein | denotes | M-CSF |
T23155 | 1128-1133 | Protein | denotes | M-CSF |
T23156 | 1389-1394 | Protein | denotes | M-CSF |
T23157 | 1842-1847 | Protein | denotes | M-CSF |
R3885 | T5153 | T5152 | themeOf | activity,increased |
R3886 | T5154 | T5153 | themeOf | NF-κB,activity |
R3887 | T5162 | T5152 | causeOf | M-CSF,increased |
bionlp-st-ge-2016-reference-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5264 | 0-5 | Protein | denotes | M-CSF |
T5265 | 14-19 | Protein | denotes | NF-κB |
T5266 | 148-153 | Protein | denotes | M-CSF |
T5267 | 162-171 | Protein | denotes | NF-κB DNA |
T5268 | 253-258 | Protein | denotes | M-CSF |
T5269 | 172-179 | Binding | denotes | binding |
T5270 | 154-161 | Positive_regulation | denotes | induced |
T5271 | 307-320 | Protein | denotes | nuclear NF-κB |
T5272 | 336-341 | Binding | denotes | bound |
T5273 | 409-414 | Protein | denotes | M-CSF |
T5274 | 429-434 | Protein | denotes | NF-κB |
T5275 | 439-446 | Binding | denotes | binding |
T5276 | 423-428 | Regulation | denotes | alter |
T5277 | 516-538 | Protein | denotes | pNF-κB-SEAP constructs |
T5278 | 555-560 | Protein | denotes | NF-κB |
T5279 | 590-595 | Protein | denotes | M-CSF |
T5280 | 666-678 | Protein | denotes | SEAP release |
T5281 | 487-499 | Gene_expression | denotes | transfecting |
T5282 | 654-662 | Positive_regulation | denotes | increase |
T5283 | 782-786 | Protein | denotes | pTAL |
T5284 | 787-791 | Protein | denotes | SEAP |
T5285 | 810-829 | Protein | denotes | NF-κB binding sites |
T5286 | 802-809 | Negative_regulation | denotes | lacking |
T5287 | 867-886 | Protein | denotes | pTAL-SEAP construct |
T5288 | 903-907 | Protein | denotes | SEAP |
T5289 | 938-943 | Protein | denotes | M-CSF |
T5290 | 846-857 | Gene_expression | denotes | transfected |
T5291 | 846-857 | Positive_regulation | denotes | transfected |
T5292 | 895-902 | Gene_expression | denotes | produce |
T5293 | 2016-2021 | Protein | denotes | M-CSF |
T5294 | 2030-2035 | Protein | denotes | NF-κB |
T5295 | 2022-2029 | Positive_regulation | denotes | induced |
T5296 | 2140-2145 | Protein | denotes | NF-κB |
T5297 | 2146-2150 | Protein | denotes | SEAP |
T5298 | 2260-2274 | Protein | denotes | NF-κB reporter |
T5299 | 2250-2259 | Positive_regulation | denotes | increased |
T5300 | 2364-2369 | Protein | denotes | M-CSF |
T5301 | 2378-2383 | Protein | denotes | NF-κB |
T23195 | 1001-1006 | Protein | denotes | M-CSF |
T23196 | 1015-1020 | Protein | denotes | NF-κB |
T23197 | 1007-1014 | Positive_regulation | denotes | induces |
T23198 | 1128-1133 | Protein | denotes | M-CSF |
T23199 | 1156-1161 | Protein | denotes | NF-κB |
T23200 | 1166-1173 | Binding | denotes | binding |
T23201 | 1348-1370 | Protein | denotes | pNF-κB-SEAP constructs |
T23202 | 1389-1394 | Protein | denotes | M-CSF |
T23203 | 1471-1476 | Protein | denotes | NF-κB |
T23204 | 1526-1530 | Protein | denotes | SEAP |
T23205 | 1599-1603 | Protein | denotes | SEAP |
T23206 | 1531-1539 | Localization | denotes | secreted |
T23207 | 1531-1539 | Localization | denotes | secreted |
T23208 | 1587-1595 | Positive_regulation | denotes | increase |
T23209 | 1730-1733 | Protein | denotes | pNF |
T23210 | 1734-1736 | Protein | denotes | κB |
T23211 | 1737-1741 | Protein | denotes | SEAP |
T23212 | 1824-1847 | Protein | denotes | mouse recombinant M-CSF |
R3907 | T5266 | T5270 | causeOf | M-CSF,induced |
R3908 | T5267 | T5269 | themeOf | NF-κB DNA,binding |
R3909 | T5269 | T5270 | themeOf | binding,induced |
R3910 | T5271 | T5272 | themeOf | nuclear NF-κB,bound |
R3911 | T5273 | T5276 | causeOf | M-CSF,alter |
R3912 | T5274 | T5275 | themeOf | NF-κB,binding |
R3913 | T5275 | T5276 | themeOf | binding,alter |
R3914 | T5277 | T5281 | themeOf | pNF-κB-SEAP constructs,transfecting |
R3915 | T5280 | T5282 | themeOf | SEAP release,increase |
R3916 | T5285 | T5286 | themeOf | NF-κB binding sites,lacking |
R3917 | T5287 | T5290 | themeOf | pTAL-SEAP construct,transfected |
R3918 | T5288 | T5292 | themeOf | SEAP,produce |
R3919 | T5290 | T5291 | themeOf | transfected,transfected |
R3920 | T5293 | T5295 | causeOf | M-CSF,induced |
R3921 | T5294 | T5295 | themeOf | NF-κB,induced |
R3922 | T5298 | T5299 | themeOf | NF-κB reporter,increased |
R17695 | T23195 | T23197 | causeOf | M-CSF,induces |
R17696 | T23196 | T23197 | themeOf | NF-κB,induces |
R17697 | T23199 | T23200 | themeOf | NF-κB,binding |
R17698 | T23203 | T23206 | themeOf | NF-κB,secreted |
R17699 | T23204 | T23207 | themeOf | SEAP,secreted |
R17700 | T23205 | T23208 | themeOf | SEAP,increase |
events-check-again
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5252 | 0-5 | Protein | denotes | M-CSF |
T5253 | 148-153 | Protein | denotes | M-CSF |
T5254 | 253-258 | Protein | denotes | M-CSF |
T5255 | 409-414 | Protein | denotes | M-CSF |
T5256 | 590-595 | Protein | denotes | M-CSF |
T5257 | 938-943 | Protein | denotes | M-CSF |
T5258 | 2016-2021 | Protein | denotes | M-CSF |
T5259 | 2215-2220 | Protein | denotes | M-CSF |
T5260 | 2250-2259 | Positive_regulation | denotes | increased |
T5261 | 2260-2265 | Protein | denotes | NF-κB |
T5262 | 2275-2283 | Positive_regulation | denotes | activity |
T5263 | 2364-2369 | Protein | denotes | M-CSF |
T23191 | 1001-1006 | Protein | denotes | M-CSF |
T23192 | 1128-1133 | Protein | denotes | M-CSF |
T23193 | 1389-1394 | Protein | denotes | M-CSF |
T23194 | 1842-1847 | Protein | denotes | M-CSF |
R3904 | T5259 | T5260 | causeOf | M-CSF,increased |
R3905 | T5261 | T5262 | themeOf | NF-κB,activity |
R3906 | T5262 | T5260 | themeOf | activity,increased |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5184 | 111-115 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | Cell |
T5185 | 625-630 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T5186 | 2101-2106 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T5187 | 2244-2249 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T5188 | 2321-2326 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T23169 | 1656-1661 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T23170 | 1677-1682 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5176 | 168-179 | http://purl.obolibrary.org/obo/GO_0003677 | denotes | DNA binding |
T5177 | 435-446 | http://purl.obolibrary.org/obo/GO_0003677 | denotes | DNA binding |
T5178 | 172-179 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
T5179 | 439-446 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
T5180 | 571-578 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
T5181 | 816-823 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
T5182 | 810-823 | http://purl.obolibrary.org/obo/GO_0051059 | denotes | NF-κB binding |
T5183 | 2022-2044 | http://purl.obolibrary.org/obo/GO_0004704 | denotes | induced NF-κB activity |
T23167 | 1162-1173 | http://purl.obolibrary.org/obo/GO_0003677 | denotes | DNA binding |
T23168 | 1166-1173 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5174 | 2022-2044 | http://purl.obolibrary.org/obo/GO_0004704 | denotes | induced NF-κB activity |
T5175 | 2384-2399 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcriptional |
T23166 | 1021-1036 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcriptional |
UBERON-AE
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T22809 | 1764-1769 | http://purl.obolibrary.org/obo/UBERON_0001977 | denotes | serum |
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4910 | 0-5 | NN | denotes | M-CSF |
T4911 | 6-13 | VB | denotes | Induces |
T4912 | 14-19 | NN | denotes | NF-κB |
T4913 | 20-35 | JJ | denotes | Transcriptional |
T4914 | 36-44 | NN | denotes | Activity |
T4915 | 45-47 | IN | denotes | in |
T4916 | 48-53 | JJ | denotes | Human |
T4917 | 54-70 | NNP | denotes | Monocyte–Derived |
T4918 | 71-82 | NN | denotes | Macrophages |
T4919 | 83-84 | -LRB- | denotes | ( |
T4920 | 84-88 | NN | denotes | MDMs |
T4921 | 88-89 | -RRB- | denotes | ) |
T4922 | 90-93 | CC | denotes | and |
T4923 | 94-99 | NNP | denotes | Mouse |
T4924 | 100-110 | NNP | denotes | Macrophage |
T4925 | 111-115 | NNP | denotes | Cell |
T4926 | 116-120 | NNP | denotes | Line |
T4927 | 120-121 | -COMMA- | denotes | , |
T4928 | 122-125 | NN | denotes | RAW |
T4929 | 126-131 | CD | denotes | 264.7 |
T4930 | 132-134 | TO | denotes | To |
T4931 | 135-144 | VB | denotes | determine |
T4932 | 145-147 | IN | denotes | if |
T4933 | 148-153 | NN | denotes | M-CSF |
T4934 | 154-161 | VB | denotes | induced |
T4935 | 162-167 | NN | denotes | NF-κB |
T4936 | 168-171 | NN | denotes | DNA |
T4937 | 172-179 | NN | denotes | binding |
T4938 | 180-182 | IN | denotes | in |
T4939 | 183-188 | JJ | denotes | human |
T4940 | 189-200 | NN | denotes | macrophages |
T4941 | 200-201 | -COMMA- | denotes | , |
T4942 | 202-204 | PRP | denotes | we |
T4943 | 205-214 | VB | denotes | performed |
T4944 | 215-219 | NN | denotes | EMSA |
T4945 | 220-228 | NN | denotes | analysis |
T4946 | 229-231 | IN | denotes | on |
T4947 | 232-239 | JJ | denotes | nuclear |
T4948 | 240-247 | NN | denotes | lysates |
T4949 | 248-252 | IN | denotes | from |
T4950 | 253-266 | JJ | denotes | M-CSF-treated |
T4951 | 267-272 | NN | denotes | MDMs. |
T4952 | 273-280 | JJ | denotes | Similar |
T4953 | 281-283 | TO | denotes | to |
T4954 | 284-292 | JJ | denotes | previous |
T4955 | 293-300 | NN | denotes | reports |
T4956 | 301-302 | -LRB- | denotes | [ |
T4957 | 302-304 | CD | denotes | 11 |
T4958 | 304-305 | -RRB- | denotes | ] |
T4959 | 305-306 | -COMMA- | denotes | , |
T4960 | 307-314 | JJ | denotes | nuclear |
T4961 | 315-320 | NN | denotes | NF-κB |
T4962 | 321-335 | RB | denotes | constitutively |
T4963 | 336-341 | VB | denotes | bound |
T4964 | 342-345 | NN | denotes | DNA |
T4965 | 346-348 | IN | denotes | in |
T4966 | 349-363 | JJ | denotes | non-stimulated |
T4967 | 364-373 | NN | denotes | monocytes |
T4968 | 374-375 | -LRB- | denotes | ( |
T4969 | 375-381 | NN | denotes | Figure |
T4970 | 382-384 | NN | denotes | 1A |
T4971 | 384-385 | -RRB- | denotes | ) |
T4972 | 387-400 | RB | denotes | Interestingly |
T4973 | 400-401 | -COMMA- | denotes | , |
T4974 | 402-408 | VB | denotes | adding |
T4975 | 409-414 | NN | denotes | M-CSF |
T4976 | 415-418 | VB | denotes | did |
T4977 | 419-422 | RB | denotes | not |
T4978 | 423-428 | VB | denotes | alter |
T4979 | 429-434 | NN | denotes | NF-κB |
T4980 | 435-438 | NN | denotes | DNA |
T4981 | 439-446 | NN | denotes | binding |
T4982 | 447-449 | IN | denotes | by |
T4983 | 450-454 | NN | denotes | EMSA |
T4984 | 456-458 | IN | denotes | In |
T4985 | 459-467 | NN | denotes | contrast |
T4986 | 467-468 | -COMMA- | denotes | , |
T4987 | 469-474 | IN | denotes | after |
T4988 | 475-486 | RB | denotes | transiently |
T4989 | 487-499 | VB | denotes | transfecting |
T4990 | 500-505 | JJ | denotes | human |
T4991 | 506-510 | NN | denotes | MDMs |
T4992 | 511-515 | IN | denotes | with |
T4993 | 516-527 | NN | denotes | pNF-κB-SEAP |
T4994 | 528-538 | NN | denotes | constructs |
T4995 | 539-549 | VB | denotes | containing |
T4996 | 550-554 | CD | denotes | four |
T4997 | 555-560 | NN | denotes | NF-κB |
T4998 | 561-570 | NN | denotes | consensus |
T4999 | 571-578 | NN | denotes | binding |
T5000 | 579-588 | NN | denotes | sequences |
T5001 | 588-589 | -COMMA- | denotes | , |
T5002 | 590-595 | NN | denotes | M-CSF |
T5003 | 596-605 | NN | denotes | treatment |
T5004 | 606-608 | IN | denotes | of |
T5005 | 609-612 | DT | denotes | the |
T5006 | 613-624 | VB | denotes | transfected |
T5007 | 625-630 | NN | denotes | cells |
T5008 | 631-639 | VB | denotes | resulted |
T5009 | 640-642 | IN | denotes | in |
T5010 | 643-644 | DT | denotes | a |
T5011 | 645-653 | JJ | denotes | 2.3-fold |
T5012 | 654-662 | NN | denotes | increase |
T5013 | 663-665 | IN | denotes | in |
T5014 | 666-670 | NN | denotes | SEAP |
T5015 | 671-678 | NN | denotes | release |
T5016 | 679-681 | IN | denotes | in |
T5017 | 682-685 | DT | denotes | the |
T5018 | 686-693 | NN | denotes | culture |
T5019 | 694-699 | NN | denotes | media |
T5020 | 700-708 | VB | denotes | compared |
T5021 | 709-711 | TO | denotes | to |
T5022 | 712-715 | NNP | denotes | PBS |
T5023 | 716-717 | -LRB- | denotes | ( |
T5024 | 717-724 | NN | denotes | vehicle |
T5025 | 724-725 | -RRB- | denotes | ) |
T5026 | 725-733 | JJ | denotes | -treated |
T5027 | 734-745 | VB | denotes | transfected |
T5028 | 746-750 | NN | denotes | MDMs |
T5029 | 751-752 | -LRB- | denotes | ( |
T5030 | 752-758 | NN | denotes | Figure |
T5031 | 759-761 | NN | denotes | 1B |
T5032 | 761-762 | -RRB- | denotes | ) |
T5033 | 764-766 | IN | denotes | As |
T5034 | 767-768 | DT | denotes | a |
T5035 | 769-776 | NN | denotes | control |
T5036 | 776-777 | -COMMA- | denotes | , |
T5037 | 778-781 | DT | denotes | the |
T5038 | 782-791 | NN | denotes | pTAL-SEAP |
T5039 | 792-801 | NN | denotes | construct |
T5040 | 802-809 | VB | denotes | lacking |
T5041 | 810-815 | NN | denotes | NF-κB |
T5042 | 816-823 | NN | denotes | binding |
T5043 | 824-829 | NN | denotes | sites |
T5044 | 830-833 | VB | denotes | was |
T5045 | 834-838 | VB | denotes | used |
T5046 | 840-845 | NN | denotes | Cells |
T5047 | 846-857 | VB | denotes | transfected |
T5048 | 858-862 | IN | denotes | with |
T5049 | 863-866 | DT | denotes | the |
T5050 | 867-876 | NN | denotes | pTAL-SEAP |
T5051 | 877-886 | NN | denotes | construct |
T5052 | 887-890 | VB | denotes | did |
T5053 | 891-894 | RB | denotes | not |
T5054 | 895-902 | VB | denotes | produce |
T5055 | 903-907 | NN | denotes | SEAP |
T5056 | 908-910 | IN | denotes | in |
T5057 | 911-914 | DT | denotes | the |
T5058 | 915-922 | NN | denotes | absence |
T5059 | 923-925 | CC | denotes | or |
T5060 | 926-934 | NN | denotes | presence |
T5061 | 935-937 | IN | denotes | of |
T5062 | 938-943 | NN | denotes | M-CSF |
T5063 | 944-945 | -LRB- | denotes | ( |
T5064 | 945-951 | NN | denotes | Figure |
T5065 | 952-954 | NN | denotes | 1B |
T5066 | 954-955 | -RRB- | denotes | ) |
T5067 | 1987-1989 | PRP | denotes | We |
T5068 | 1990-1994 | RB | denotes | next |
T5069 | 1995-2007 | VB | denotes | investigated |
T5070 | 2008-2015 | IN | denotes | whether |
T5071 | 2016-2021 | NN | denotes | M-CSF |
T5072 | 2022-2029 | VB | denotes | induced |
T5073 | 2030-2035 | NN | denotes | NF-κB |
T5074 | 2036-2044 | NN | denotes | activity |
T5075 | 2045-2047 | IN | denotes | in |
T5076 | 2048-2051 | DT | denotes | the |
T5077 | 2052-2057 | NN | denotes | mouse |
T5078 | 2058-2068 | NN | denotes | macrophage |
T5079 | 2069-2073 | NN | denotes | cell |
T5080 | 2074-2078 | NN | denotes | line |
T5081 | 2078-2079 | -COMMA- | denotes | , |
T5082 | 2080-2083 | NN | denotes | RAW |
T5083 | 2084-2089 | CD | denotes | 264.7 |
T5084 | 2091-2094 | NN | denotes | RAW |
T5085 | 2095-2100 | CD | denotes | 264.7 |
T5086 | 2101-2106 | NN | denotes | cells |
T5087 | 2107-2111 | VB | denotes | were |
T5088 | 2112-2123 | VB | denotes | transfected |
T5089 | 2124-2128 | IN | denotes | with |
T5090 | 2129-2135 | CC | denotes | either |
T5091 | 2136-2139 | DT | denotes | the |
T5092 | 2140-2150 | NN | denotes | NF-κB-SEAP |
T5093 | 2151-2159 | NN | denotes | reporter |
T5094 | 2160-2162 | CC | denotes | or |
T5095 | 2163-2170 | NN | denotes | control |
T5096 | 2171-2180 | NN | denotes | pTAL-SEAP |
T5097 | 2181-2190 | NN | denotes | construct |
T5098 | 2192-2194 | IN | denotes | As |
T5099 | 2195-2200 | VB | denotes | shown |
T5100 | 2201-2203 | IN | denotes | in |
T5101 | 2204-2210 | NN | denotes | Figure |
T5102 | 2211-2213 | NN | denotes | 1C |
T5103 | 2213-2214 | -COMMA- | denotes | , |
T5104 | 2215-2220 | NN | denotes | M-CSF |
T5105 | 2221-2230 | NN | denotes | treatment |
T5106 | 2231-2233 | IN | denotes | of |
T5107 | 2234-2237 | NN | denotes | RAW |
T5108 | 2238-2243 | CD | denotes | 264.7 |
T5109 | 2244-2249 | NN | denotes | cells |
T5110 | 2250-2259 | VB | denotes | increased |
T5111 | 2260-2265 | NN | denotes | NF-κB |
T5112 | 2266-2274 | NN | denotes | reporter |
T5113 | 2275-2283 | NN | denotes | activity |
T5114 | 2284-2286 | IN | denotes | by |
T5115 | 2287-2295 | RB | denotes | 2.5-fold |
T5116 | 2296-2300 | IN | denotes | over |
T5117 | 2301-2305 | DT | denotes | that |
T5118 | 2306-2308 | IN | denotes | of |
T5119 | 2309-2320 | JJ | denotes | non-treated |
T5120 | 2321-2326 | NN | denotes | cells |
T5121 | 2328-2336 | RB | denotes | Together |
T5122 | 2336-2337 | -COMMA- | denotes | , |
T5123 | 2338-2341 | PRP-DOLLAR- | denotes | our |
T5124 | 2342-2346 | NN | denotes | data |
T5125 | 2347-2358 | VB | denotes | demonstrate |
T5126 | 2359-2363 | IN | denotes | that |
T5127 | 2364-2369 | NN | denotes | M-CSF |
T5128 | 2370-2377 | VB | denotes | induced |
T5129 | 2378-2383 | NN | denotes | NF-κB |
T5130 | 2384-2399 | JJ | denotes | transcriptional |
T5131 | 2400-2408 | NN | denotes | activity |
T5132 | 2409-2411 | IN | denotes | in |
T5133 | 2412-2423 | NN | denotes | macrophages |
T22987 | 1001-1006 | NN | denotes | M-CSF |
T22988 | 1007-1014 | VB | denotes | induces |
T22989 | 1015-1020 | NN | denotes | NF-κB |
T22990 | 1021-1036 | JJ | denotes | transcriptional |
T22991 | 1037-1045 | NN | denotes | activity |
T22992 | 1046-1048 | IN | denotes | in |
T22993 | 1049-1060 | NN | denotes | macrophages |
T22994 | 1062-1063 | -LRB- | denotes | ( |
T22995 | 1063-1064 | NN | denotes | A |
T22996 | 1064-1065 | -RRB- | denotes | ) |
T22997 | 1066-1072 | NN | denotes | Nuclei |
T22998 | 1073-1077 | VB | denotes | were |
T22999 | 1078-1087 | VB | denotes | extracted |
T23000 | 1088-1092 | IN | denotes | from |
T23001 | 1093-1098 | JJ | denotes | human |
T23002 | 1099-1103 | NN | denotes | MDMs |
T23003 | 1104-1111 | VB | denotes | treated |
T23004 | 1112-1119 | IN | denotes | without |
T23005 | 1120-1122 | CC | denotes | or |
T23006 | 1123-1127 | IN | denotes | with |
T23007 | 1128-1133 | NN | denotes | M-CSF |
T23008 | 1134-1137 | IN | denotes | for |
T23009 | 1138-1140 | CD | denotes | 15 |
T23010 | 1141-1143 | CC | denotes | or |
T23011 | 1144-1146 | CD | denotes | 30 |
T23012 | 1147-1154 | NN | denotes | minutes |
T23013 | 1156-1161 | NN | denotes | NF-κB |
T23014 | 1162-1165 | NN | denotes | DNA |
T23015 | 1166-1173 | NN | denotes | binding |
T23016 | 1174-1182 | NN | denotes | activity |
T23017 | 1183-1186 | VB | denotes | was |
T23018 | 1187-1195 | VB | denotes | analyzed |
T23019 | 1196-1198 | IN | denotes | by |
T23020 | 1199-1203 | NNP | denotes | EMSA |
T23021 | 1204-1209 | NNP | denotes | Shown |
T23022 | 1210-1212 | VB | denotes | is |
T23023 | 1213-1214 | DT | denotes | a |
T23024 | 1215-1229 | JJ | denotes | representative |
T23025 | 1230-1234 | NN | denotes | blot |
T23026 | 1235-1239 | IN | denotes | from |
T23027 | 1240-1245 | CD | denotes | three |
T23028 | 1246-1257 | JJ | denotes | independent |
T23029 | 1258-1269 | NN | denotes | experiments |
T23030 | 1271-1273 | NN | denotes | NS |
T23031 | 1273-1274 | -COLON- | denotes | : |
T23032 | 1275-1290 | JJ | denotes | non-stimulated. |
T23033 | 1291-1292 | -LRB- | denotes | ( |
T23034 | 1292-1293 | NN | denotes | B |
T23035 | 1293-1294 | -RRB- | denotes | ) |
T23036 | 1295-1300 | JJ | denotes | Human |
T23037 | 1301-1305 | NN | denotes | MDMs |
T23038 | 1306-1317 | RB | denotes | transiently |
T23039 | 1318-1329 | VB | denotes | transfected |
T23040 | 1330-1334 | IN | denotes | with |
T23041 | 1335-1344 | NN | denotes | pTAL-SEAP |
T23042 | 1345-1347 | CC | denotes | or |
T23043 | 1348-1359 | NN | denotes | pNF-κB-SEAP |
T23044 | 1360-1370 | NN | denotes | constructs |
T23045 | 1371-1375 | VB | denotes | were |
T23046 | 1376-1383 | VB | denotes | treated |
T23047 | 1384-1388 | IN | denotes | with |
T23048 | 1389-1394 | NN | denotes | M-CSF |
T23049 | 1395-1397 | IN | denotes | in |
T23050 | 1398-1404 | JJ | denotes | X-vivo |
T23051 | 1405-1411 | NN | denotes | medium |
T23052 | 1412-1415 | CC | denotes | and |
T23053 | 1416-1425 | VB | denotes | incubated |
T23054 | 1426-1429 | IN | denotes | for |
T23055 | 1430-1431 | CD | denotes | 6 |
T23056 | 1432-1437 | NN | denotes | hours |
T23057 | 1438-1444 | IN | denotes | before |
T23058 | 1445-1448 | DT | denotes | the |
T23059 | 1449-1459 | NN | denotes | collection |
T23060 | 1460-1462 | IN | denotes | of |
T23061 | 1463-1469 | NN | denotes | medium |
T23062 | 1471-1476 | NN | denotes | NF-κB |
T23063 | 1477-1485 | NN | denotes | activity |
T23064 | 1486-1489 | VB | denotes | was |
T23065 | 1490-1498 | VB | denotes | analyzed |
T23066 | 1499-1501 | IN | denotes | by |
T23067 | 1502-1511 | VB | denotes | measuring |
T23068 | 1512-1515 | DT | denotes | the |
T23069 | 1516-1522 | NN | denotes | amount |
T23070 | 1523-1525 | IN | denotes | of |
T23071 | 1526-1530 | NN | denotes | SEAP |
T23072 | 1531-1539 | VB | denotes | secreted |
T23073 | 1540-1544 | IN | denotes | into |
T23074 | 1545-1548 | DT | denotes | the |
T23075 | 1549-1555 | NN | denotes | medium |
T23076 | 1556-1559 | CC | denotes | and |
T23077 | 1560-1564 | NN | denotes | data |
T23078 | 1565-1568 | VB | denotes | are |
T23079 | 1569-1578 | VB | denotes | expressed |
T23080 | 1579-1581 | IN | denotes | as |
T23081 | 1582-1586 | JJ | denotes | fold |
T23082 | 1587-1595 | NN | denotes | increase |
T23083 | 1596-1598 | IN | denotes | of |
T23084 | 1599-1603 | NN | denotes | SEAP |
T23085 | 1604-1612 | NN | denotes | activity |
T23086 | 1613-1617 | IN | denotes | over |
T23087 | 1618-1622 | DT | denotes | that |
T23088 | 1623-1625 | IN | denotes | in |
T23089 | 1626-1635 | NN | denotes | pTAL-SEAP |
T23090 | 1636-1647 | VB | denotes | transfected |
T23091 | 1648-1655 | VB | denotes | resting |
T23092 | 1656-1662 | NN | denotes | cells. |
T23093 | 1663-1664 | -LRB- | denotes | ( |
T23094 | 1664-1665 | NN | denotes | C |
T23095 | 1665-1666 | -RRB- | denotes | ) |
T23096 | 1667-1670 | NN | denotes | RAW |
T23097 | 1671-1676 | CD | denotes | 264.7 |
T23098 | 1677-1682 | NN | denotes | cells |
T23099 | 1683-1687 | VB | denotes | were |
T23100 | 1688-1699 | RB | denotes | transiently |
T23101 | 1700-1711 | VB | denotes | transfected |
T23102 | 1712-1716 | IN | denotes | with |
T23103 | 1717-1726 | NN | denotes | pTAL-SEAP |
T23104 | 1727-1729 | CC | denotes | or |
T23105 | 1730-1741 | NN | denotes | pNF-κB-SEAP |
T23106 | 1742-1751 | NN | denotes | construct |
T23107 | 1753-1758 | NN | denotes | Cells |
T23108 | 1759-1763 | VB | denotes | were |
T23109 | 1764-1769 | NN | denotes | serum |
T23110 | 1770-1777 | VB | denotes | starved |
T23111 | 1778-1781 | IN | denotes | for |
T23112 | 1782-1783 | CD | denotes | 4 |
T23113 | 1784-1789 | NN | denotes | hours |
T23114 | 1790-1795 | RB | denotes | prior |
T23115 | 1796-1798 | TO | denotes | to |
T23116 | 1799-1800 | CD | denotes | 2 |
T23117 | 1801-1806 | NN | denotes | hours |
T23118 | 1807-1818 | NN | denotes | stimulation |
T23119 | 1819-1823 | IN | denotes | with |
T23120 | 1824-1829 | NN | denotes | mouse |
T23121 | 1830-1841 | JJ | denotes | recombinant |
T23122 | 1842-1847 | NN | denotes | M-CSF |
T23123 | 1848-1849 | -LRB- | denotes | ( |
T23124 | 1849-1852 | CD | denotes | 100 |
T23125 | 1853-1858 | NN | denotes | ng/ml |
T23126 | 1858-1859 | -RRB- | denotes | ) |
T23127 | 1861-1868 | NN | denotes | Culture |
T23128 | 1869-1874 | NN | denotes | media |
T23129 | 1875-1878 | VB | denotes | was |
T23130 | 1879-1888 | VB | denotes | collected |
T23131 | 1889-1891 | TO | denotes | to |
T23132 | 1892-1899 | VB | denotes | measure |
T23133 | 1900-1904 | NN | denotes | SEAP |
T23134 | 1905-1915 | NN | denotes | production |
T23135 | 1917-1921 | NN | denotes | Data |
T23136 | 1922-1925 | VB | denotes | are |
T23137 | 1926-1935 | VB | denotes | expressed |
T23138 | 1936-1940 | JJ | denotes | mean |
T23139 | 1941-1942 | JJ | denotes | ± |
T23140 | 1943-1948 | NN | denotes | S.E.M |
T23141 | 1948-1949 | -COMMA- | denotes | , |
T23142 | 1950-1953 | IN | denotes | for |
T23143 | 1954-1959 | CD | denotes | three |
T23144 | 1960-1971 | JJ | denotes | independent |
T23145 | 1972-1983 | NN | denotes | experiments |
R3665 | T4910 | T4911 | arg1Of | M-CSF,Induces |
R3666 | T4914 | T4911 | arg2Of | Activity,Induces |
R3667 | T4914 | T4912 | arg1Of | Activity,NF-κB |
R3668 | T4914 | T4913 | arg1Of | Activity,Transcriptional |
R3669 | T4914 | T4915 | arg1Of | Activity,in |
R3670 | T4918 | T4916 | arg1Of | Macrophages,Human |
R3671 | T4918 | T4917 | arg1Of | Macrophages,Monocyte–Derived |
R3672 | T4918 | T4919 | arg1Of | Macrophages,( |
R3673 | T4918 | T4922 | arg1Of | Macrophages,and |
R3674 | T4920 | T4919 | arg2Of | MDMs,( |
R3675 | T4921 | T4919 | arg3Of | ),( |
R3676 | T4922 | T4915 | arg2Of | and,in |
R3677 | T4926 | T4922 | arg2Of | Line,and |
R3678 | T4926 | T4923 | arg1Of | Line,Mouse |
R3679 | T4926 | T4924 | arg1Of | Line,Macrophage |
R3680 | T4926 | T4925 | arg1Of | Line,Cell |
R3681 | T4926 | T4927 | arg1Of | Line,"," |
R3682 | T4928 | T4927 | arg2Of | RAW,"," |
R3683 | T4928 | T4929 | arg1Of | RAW,264.7 |
R3684 | T4931 | T4930 | arg1Of | determine,To |
R3685 | T4933 | T4934 | arg1Of | M-CSF,induced |
R3686 | T4934 | T4931 | arg2Of | induced,determine |
R3687 | T4934 | T4932 | arg1Of | induced,if |
R3688 | T4934 | T4938 | arg1Of | induced,in |
R3689 | T4937 | T4934 | arg2Of | binding,induced |
R3690 | T4937 | T4935 | arg1Of | binding,NF-κB |
R3691 | T4937 | T4936 | arg1Of | binding,DNA |
R3692 | T4940 | T4938 | arg2Of | macrophages,in |
R3693 | T4940 | T4939 | arg1Of | macrophages,human |
R3694 | T4942 | T4931 | arg1Of | we,determine |
R3695 | T4942 | T4943 | arg1Of | we,performed |
R3696 | T4943 | T4930 | modOf | performed,To |
R3697 | T4943 | T4941 | arg1Of | performed,"," |
R3698 | T4945 | T4943 | arg2Of | analysis,performed |
R3699 | T4945 | T4944 | arg1Of | analysis,EMSA |
R3700 | T4945 | T4946 | arg1Of | analysis,on |
R3701 | T4948 | T4946 | arg2Of | lysates,on |
R3702 | T4948 | T4947 | arg1Of | lysates,nuclear |
R3703 | T4948 | T4949 | arg1Of | lysates,from |
R3704 | T4948 | T4952 | arg1Of | lysates,Similar |
R3705 | T4948 | T4959 | arg1Of | lysates,"," |
R3706 | T4951 | T4949 | arg2Of | MDMs.,from |
R3707 | T4951 | T4950 | arg1Of | MDMs.,M-CSF-treated |
R3708 | T4952 | T4953 | arg1Of | Similar,to |
R3709 | T4955 | T4953 | arg2Of | reports,to |
R3710 | T4955 | T4954 | arg1Of | reports,previous |
R3711 | T4955 | T4956 | arg1Of | reports,[ |
R3712 | T4957 | T4956 | arg2Of | 11,[ |
R3713 | T4958 | T4956 | arg3Of | ],[ |
R3714 | T4961 | T4960 | arg1Of | NF-κB,nuclear |
R3715 | T4961 | T4963 | arg1Of | NF-κB,bound |
R3716 | T4963 | T4959 | arg2Of | bound,"," |
R3717 | T4963 | T4962 | arg1Of | bound,constitutively |
R3718 | T4963 | T4965 | arg1Of | bound,in |
R3719 | T4964 | T4963 | arg2Of | DNA,bound |
R3720 | T4967 | T4965 | arg2Of | monocytes,in |
R3721 | T4967 | T4966 | arg1Of | monocytes,non-stimulated |
R3722 | T4967 | T4968 | arg1Of | monocytes,( |
R3723 | T4970 | T4968 | arg2Of | 1A,( |
R3724 | T4970 | T4969 | arg1Of | 1A,Figure |
R3725 | T4971 | T4968 | arg3Of | ),( |
R3726 | T4975 | T4974 | arg1Of | M-CSF,adding |
R3727 | T4975 | T4976 | arg1Of | M-CSF,did |
R3728 | T4975 | T4978 | arg1Of | M-CSF,alter |
R3729 | T4978 | T4972 | arg1Of | alter,Interestingly |
R3730 | T4978 | T4973 | arg1Of | alter,"," |
R3731 | T4978 | T4976 | arg2Of | alter,did |
R3732 | T4978 | T4977 | arg1Of | alter,not |
R3733 | T4978 | T4982 | arg1Of | alter,by |
R3734 | T4981 | T4978 | arg2Of | binding,alter |
R3735 | T4981 | T4979 | arg1Of | binding,NF-κB |
R3736 | T4981 | T4980 | arg1Of | binding,DNA |
R3737 | T4983 | T4982 | arg2Of | EMSA,by |
R3738 | T4985 | T4984 | arg2Of | contrast,In |
R3739 | T4989 | T4987 | arg2Of | transfecting,after |
R3740 | T4989 | T4988 | arg1Of | transfecting,transiently |
R3741 | T4989 | T4992 | arg1Of | transfecting,with |
R3742 | T4991 | T4989 | arg2Of | MDMs,transfecting |
R3743 | T4991 | T4990 | arg1Of | MDMs,human |
R3744 | T4994 | T4992 | arg2Of | constructs,with |
R3745 | T4994 | T4993 | arg1Of | constructs,pNF-κB-SEAP |
R3746 | T4994 | T4995 | arg1Of | constructs,containing |
R3747 | T5000 | T4995 | arg2Of | sequences,containing |
R3748 | T5000 | T4996 | arg1Of | sequences,four |
R3749 | T5000 | T4997 | arg1Of | sequences,NF-κB |
R3750 | T5000 | T4998 | arg1Of | sequences,consensus |
R3751 | T5000 | T4999 | arg1Of | sequences,binding |
R3752 | T5003 | T4989 | arg1Of | treatment,transfecting |
R3753 | T5003 | T5002 | arg1Of | treatment,M-CSF |
R3754 | T5003 | T5004 | arg1Of | treatment,of |
R3755 | T5003 | T5008 | arg1Of | treatment,resulted |
R3756 | T5007 | T5004 | arg2Of | cells,of |
R3757 | T5007 | T5005 | arg1Of | cells,the |
R3758 | T5007 | T5006 | arg2Of | cells,transfected |
R3759 | T5008 | T4984 | arg1Of | resulted,In |
R3760 | T5008 | T4986 | arg1Of | resulted,"," |
R3761 | T5008 | T4987 | arg1Of | resulted,after |
R3762 | T5008 | T5001 | arg1Of | resulted,"," |
R3763 | T5008 | T5009 | arg1Of | resulted,in |
R3764 | T5008 | T5020 | arg1Of | resulted,compared |
R3765 | T5012 | T5009 | arg2Of | increase,in |
R3766 | T5012 | T5010 | arg1Of | increase,a |
R3767 | T5012 | T5011 | arg1Of | increase,2.3-fold |
R3768 | T5012 | T5013 | arg1Of | increase,in |
R3769 | T5012 | T5016 | arg1Of | increase,in |
R3770 | T5015 | T5013 | arg2Of | release,in |
R3771 | T5015 | T5014 | arg1Of | release,SEAP |
R3772 | T5019 | T5016 | arg2Of | media,in |
R3773 | T5019 | T5017 | arg1Of | media,the |
R3774 | T5019 | T5018 | arg1Of | media,culture |
R3775 | T5021 | T5020 | arg2Of | to,compared |
R3776 | T5024 | T5023 | arg2Of | vehicle,( |
R3777 | T5025 | T5023 | arg3Of | ),( |
R3778 | T5028 | T5021 | arg2Of | MDMs,to |
R3779 | T5028 | T5022 | arg1Of | MDMs,PBS |
R3780 | T5028 | T5023 | arg1Of | MDMs,( |
R3781 | T5028 | T5026 | arg1Of | MDMs,-treated |
R3782 | T5028 | T5027 | arg2Of | MDMs,transfected |
R3783 | T5028 | T5029 | arg1Of | MDMs,( |
R3784 | T5031 | T5029 | arg2Of | 1B,( |
R3785 | T5031 | T5030 | arg1Of | 1B,Figure |
R3786 | T5032 | T5029 | arg3Of | ),( |
R3787 | T5035 | T5033 | arg2Of | control,As |
R3788 | T5035 | T5034 | arg1Of | control,a |
R3789 | T5039 | T5037 | arg1Of | construct,the |
R3790 | T5039 | T5038 | arg1Of | construct,pTAL-SEAP |
R3791 | T5039 | T5040 | arg1Of | construct,lacking |
R3792 | T5039 | T5044 | arg1Of | construct,was |
R3793 | T5039 | T5045 | arg2Of | construct,used |
R3794 | T5043 | T5040 | arg2Of | sites,lacking |
R3795 | T5043 | T5041 | arg1Of | sites,NF-κB |
R3796 | T5043 | T5042 | arg1Of | sites,binding |
R3797 | T5045 | T5033 | arg1Of | used,As |
R3798 | T5045 | T5036 | arg1Of | used,"," |
R3799 | T5045 | T5044 | arg2Of | used,was |
R3800 | T5046 | T5047 | arg2Of | Cells,transfected |
R3801 | T5046 | T5052 | arg1Of | Cells,did |
R3802 | T5046 | T5054 | arg1Of | Cells,produce |
R3803 | T5047 | T5048 | arg1Of | transfected,with |
R3804 | T5051 | T5048 | arg2Of | construct,with |
R3805 | T5051 | T5049 | arg1Of | construct,the |
R3806 | T5051 | T5050 | arg1Of | construct,pTAL-SEAP |
R3807 | T5054 | T5052 | arg2Of | produce,did |
R3808 | T5054 | T5053 | arg1Of | produce,not |
R3809 | T5054 | T5056 | arg1Of | produce,in |
R3810 | T5055 | T5054 | arg2Of | SEAP,produce |
R3811 | T5058 | T5059 | arg1Of | absence,or |
R3812 | T5059 | T5056 | arg2Of | or,in |
R3813 | T5059 | T5057 | arg1Of | or,the |
R3814 | T5059 | T5061 | arg1Of | or,of |
R3815 | T5060 | T5059 | arg2Of | presence,or |
R3816 | T5062 | T5061 | arg2Of | M-CSF,of |
R3817 | T5062 | T5063 | arg1Of | M-CSF,( |
R3818 | T5065 | T5063 | arg2Of | 1B,( |
R3819 | T5065 | T5064 | arg1Of | 1B,Figure |
R3820 | T5066 | T5063 | arg3Of | ),( |
R3821 | T5067 | T5069 | arg1Of | We,investigated |
R3822 | T5069 | T5068 | arg1Of | investigated,next |
R3823 | T5071 | T5072 | arg1Of | M-CSF,induced |
R3824 | T5072 | T5069 | arg2Of | induced,investigated |
R3825 | T5072 | T5070 | arg1Of | induced,whether |
R3826 | T5072 | T5075 | arg1Of | induced,in |
R3827 | T5074 | T5072 | arg2Of | activity,induced |
R3828 | T5074 | T5073 | arg1Of | activity,NF-κB |
R3829 | T5080 | T5075 | arg2Of | line,in |
R3830 | T5080 | T5076 | arg1Of | line,the |
R3831 | T5080 | T5077 | arg1Of | line,mouse |
R3832 | T5080 | T5078 | arg1Of | line,macrophage |
R3833 | T5080 | T5079 | arg1Of | line,cell |
R3834 | T5080 | T5081 | arg1Of | line,"," |
R3835 | T5082 | T5081 | arg2Of | RAW,"," |
R3836 | T5082 | T5083 | arg1Of | RAW,264.7 |
R3837 | T5086 | T5084 | arg1Of | cells,RAW |
R3838 | T5086 | T5085 | arg1Of | cells,264.7 |
R3839 | T5086 | T5087 | arg1Of | cells,were |
R3840 | T5086 | T5088 | arg2Of | cells,transfected |
R3841 | T5088 | T5087 | arg2Of | transfected,were |
R3842 | T5088 | T5089 | arg1Of | transfected,with |
R3843 | T5093 | T5092 | arg1Of | reporter,NF-κB-SEAP |
R3844 | T5093 | T5094 | arg1Of | reporter,or |
R3845 | T5094 | T5089 | arg2Of | or,with |
R3846 | T5094 | T5090 | arg1Of | or,either |
R3847 | T5094 | T5091 | arg1Of | or,the |
R3848 | T5097 | T5094 | arg2Of | construct,or |
R3849 | T5097 | T5095 | arg1Of | construct,control |
R3850 | T5097 | T5096 | arg1Of | construct,pTAL-SEAP |
R3851 | T5099 | T5098 | arg2Of | shown,As |
R3852 | T5099 | T5100 | arg1Of | shown,in |
R3853 | T5102 | T5100 | arg2Of | 1C,in |
R3854 | T5102 | T5101 | arg1Of | 1C,Figure |
R3855 | T5105 | T5104 | arg1Of | treatment,M-CSF |
R3856 | T5105 | T5106 | arg1Of | treatment,of |
R3857 | T5105 | T5110 | arg1Of | treatment,increased |
R3858 | T5109 | T5106 | arg2Of | cells,of |
R3859 | T5109 | T5107 | arg1Of | cells,RAW |
R3860 | T5109 | T5108 | arg1Of | cells,264.7 |
R3861 | T5110 | T5098 | arg1Of | increased,As |
R3862 | T5110 | T5103 | arg1Of | increased,"," |
R3863 | T5110 | T5114 | arg1Of | increased,by |
R3864 | T5110 | T5116 | arg1Of | increased,over |
R3865 | T5113 | T5110 | arg2Of | activity,increased |
R3866 | T5113 | T5111 | arg1Of | activity,NF-κB |
R3867 | T5113 | T5112 | arg1Of | activity,reporter |
R3868 | T5115 | T5114 | arg2Of | 2.5-fold,by |
R3869 | T5117 | T5116 | arg2Of | that,over |
R3870 | T5117 | T5118 | arg1Of | that,of |
R3871 | T5120 | T5118 | arg2Of | cells,of |
R3872 | T5120 | T5119 | arg1Of | cells,non-treated |
R3873 | T5124 | T5123 | arg1Of | data,our |
R3874 | T5124 | T5125 | arg1Of | data,demonstrate |
R3875 | T5125 | T5121 | arg1Of | demonstrate,Together |
R3876 | T5125 | T5122 | arg1Of | demonstrate,"," |
R3877 | T5127 | T5128 | arg1Of | M-CSF,induced |
R3878 | T5128 | T5125 | arg2Of | induced,demonstrate |
R3879 | T5128 | T5126 | arg1Of | induced,that |
R3880 | T5131 | T5128 | arg2Of | activity,induced |
R3881 | T5131 | T5129 | arg1Of | activity,NF-κB |
R3882 | T5131 | T5130 | arg1Of | activity,transcriptional |
R3883 | T5131 | T5132 | arg1Of | activity,in |
R3884 | T5133 | T5132 | arg2Of | macrophages,in |
R17531 | T22987 | T22988 | arg1Of | M-CSF,induces |
R17532 | T22988 | T22992 | arg1Of | induces,in |
R17533 | T22991 | T22988 | arg2Of | activity,induces |
R17534 | T22991 | T22989 | arg1Of | activity,NF-κB |
R17535 | T22991 | T22990 | arg1Of | activity,transcriptional |
R17536 | T22993 | T22992 | arg2Of | macrophages,in |
R17537 | T22995 | T22994 | arg2Of | A,( |
R17538 | T22996 | T22994 | arg3Of | ),( |
R17539 | T22997 | T22994 | arg1Of | Nuclei,( |
R17540 | T22997 | T22998 | arg1Of | Nuclei,were |
R17541 | T22997 | T22999 | arg2Of | Nuclei,extracted |
R17542 | T22999 | T22998 | arg2Of | extracted,were |
R17543 | T22999 | T23000 | arg1Of | extracted,from |
R17544 | T23002 | T23000 | arg2Of | MDMs,from |
R17545 | T23002 | T23001 | arg1Of | MDMs,human |
R17546 | T23002 | T23003 | arg2Of | MDMs,treated |
R17547 | T23003 | T23004 | arg1Of | treated,without |
R17548 | T23003 | T23006 | arg1Of | treated,with |
R17549 | T23004 | T23005 | arg1Of | without,or |
R17550 | T23006 | T23005 | arg2Of | with,or |
R17551 | T23007 | T23004 | arg2Of | M-CSF,without |
R17552 | T23007 | T23006 | arg2Of | M-CSF,with |
R17553 | T23007 | T23008 | arg1Of | M-CSF,for |
R17554 | T23009 | T23010 | arg1Of | 15,or |
R17555 | T23011 | T23010 | arg2Of | 30,or |
R17556 | T23012 | T23008 | arg2Of | minutes,for |
R17557 | T23012 | T23009 | arg1Of | minutes,15 |
R17558 | T23012 | T23011 | arg1Of | minutes,30 |
R17559 | T23013 | T23022 | arg1Of | NF-κB,is |
R17560 | T23016 | T23014 | arg1Of | activity,DNA |
R17561 | T23016 | T23015 | arg1Of | activity,binding |
R17562 | T23016 | T23017 | arg1Of | activity,was |
R17563 | T23016 | T23018 | arg2Of | activity,analyzed |
R17564 | T23018 | T23017 | arg2Of | analyzed,was |
R17565 | T23021 | T23018 | arg1Of | Shown,analyzed |
R17566 | T23021 | T23019 | arg2Of | Shown,by |
R17567 | T23021 | T23020 | arg1Of | Shown,EMSA |
R17568 | T23022 | T23017 | modOf | is,was |
R17569 | T23025 | T23022 | arg2Of | blot,is |
R17570 | T23025 | T23023 | arg1Of | blot,a |
R17571 | T23025 | T23024 | arg1Of | blot,representative |
R17572 | T23025 | T23026 | arg1Of | blot,from |
R17573 | T23029 | T23026 | arg2Of | experiments,from |
R17574 | T23029 | T23027 | arg1Of | experiments,three |
R17575 | T23029 | T23028 | arg1Of | experiments,independent |
R17576 | T23030 | T23031 | arg1Of | NS,: |
R17577 | T23030 | T23045 | modOf | NS,were |
R17578 | T23034 | T23033 | arg2Of | B,( |
R17579 | T23035 | T23033 | arg3Of | ),( |
R17580 | T23037 | T23032 | arg1Of | MDMs,non-stimulated. |
R17581 | T23037 | T23033 | arg1Of | MDMs,( |
R17582 | T23037 | T23036 | arg1Of | MDMs,Human |
R17583 | T23037 | T23039 | arg2Of | MDMs,transfected |
R17584 | T23037 | T23045 | arg1Of | MDMs,were |
R17585 | T23037 | T23046 | arg2Of | MDMs,treated |
R17586 | T23037 | T23053 | arg2Of | MDMs,incubated |
R17587 | T23039 | T23038 | arg1Of | transfected,transiently |
R17588 | T23039 | T23040 | arg1Of | transfected,with |
R17589 | T23041 | T23042 | arg1Of | pTAL-SEAP,or |
R17590 | T23043 | T23042 | arg2Of | pNF-κB-SEAP,or |
R17591 | T23044 | T23040 | arg2Of | constructs,with |
R17592 | T23044 | T23041 | arg1Of | constructs,pTAL-SEAP |
R17593 | T23044 | T23043 | arg1Of | constructs,pNF-κB-SEAP |
R17594 | T23046 | T23047 | arg1Of | treated,with |
R17595 | T23046 | T23052 | arg1Of | treated,and |
R17596 | T23048 | T23047 | arg2Of | M-CSF,with |
R17597 | T23048 | T23049 | arg1Of | M-CSF,in |
R17598 | T23051 | T23049 | arg2Of | medium,in |
R17599 | T23051 | T23050 | arg1Of | medium,X-vivo |
R17600 | T23052 | T23045 | arg2Of | and,were |
R17601 | T23053 | T23052 | arg2Of | incubated,and |
R17602 | T23053 | T23054 | arg1Of | incubated,for |
R17603 | T23053 | T23057 | arg1Of | incubated,before |
R17604 | T23056 | T23054 | arg2Of | hours,for |
R17605 | T23056 | T23055 | arg1Of | hours,6 |
R17606 | T23059 | T23057 | arg2Of | collection,before |
R17607 | T23059 | T23058 | arg1Of | collection,the |
R17608 | T23059 | T23060 | arg1Of | collection,of |
R17609 | T23061 | T23060 | arg2Of | medium,of |
R17610 | T23063 | T23062 | arg1Of | activity,NF-κB |
R17611 | T23063 | T23064 | arg1Of | activity,was |
R17612 | T23063 | T23065 | arg2Of | activity,analyzed |
R17613 | T23065 | T23064 | arg2Of | analyzed,was |
R17614 | T23065 | T23066 | arg1Of | analyzed,by |
R17615 | T23065 | T23076 | arg1Of | analyzed,and |
R17616 | T23067 | T23066 | arg2Of | measuring,by |
R17617 | T23069 | T23067 | arg2Of | amount,measuring |
R17618 | T23069 | T23068 | arg1Of | amount,the |
R17619 | T23069 | T23070 | arg1Of | amount,of |
R17620 | T23069 | T23072 | arg2Of | amount,secreted |
R17621 | T23071 | T23070 | arg2Of | SEAP,of |
R17622 | T23072 | T23073 | arg1Of | secreted,into |
R17623 | T23075 | T23073 | arg2Of | medium,into |
R17624 | T23075 | T23074 | arg1Of | medium,the |
R17625 | T23077 | T23078 | arg1Of | data,are |
R17626 | T23077 | T23079 | arg2Of | data,expressed |
R17627 | T23079 | T23076 | arg2Of | expressed,and |
R17628 | T23079 | T23078 | arg2Of | expressed,are |
R17629 | T23079 | T23080 | arg1Of | expressed,as |
R17630 | T23082 | T23083 | arg1Of | increase,of |
R17631 | T23082 | T23086 | arg1Of | increase,over |
R17632 | T23085 | T23083 | arg2Of | activity,of |
R17633 | T23085 | T23084 | arg1Of | activity,SEAP |
R17634 | T23087 | T23086 | arg2Of | that,over |
R17635 | T23087 | T23088 | arg1Of | that,in |
R17636 | T23092 | T23088 | arg2Of | cells.,in |
R17637 | T23092 | T23089 | arg1Of | cells.,pTAL-SEAP |
R17638 | T23092 | T23090 | arg2Of | cells.,transfected |
R17639 | T23092 | T23091 | arg1Of | cells.,resting |
R17640 | T23092 | T23093 | arg1Of | cells.,( |
R17641 | T23094 | T23093 | arg2Of | C,( |
R17642 | T23095 | T23093 | arg3Of | ),( |
R17643 | T23098 | T23081 | arg1Of | cells,fold |
R17644 | T23098 | T23082 | arg1Of | cells,increase |
R17645 | T23098 | T23096 | arg1Of | cells,RAW |
R17646 | T23098 | T23097 | arg1Of | cells,264.7 |
R17647 | T23098 | T23099 | arg1Of | cells,were |
R17648 | T23098 | T23101 | arg2Of | cells,transfected |
R17649 | T23101 | T23080 | arg2Of | transfected,as |
R17650 | T23101 | T23099 | arg2Of | transfected,were |
R17651 | T23101 | T23100 | arg1Of | transfected,transiently |
R17652 | T23101 | T23102 | arg1Of | transfected,with |
R17653 | T23103 | T23104 | arg1Of | pTAL-SEAP,or |
R17654 | T23104 | T23102 | arg2Of | or,with |
R17655 | T23106 | T23104 | arg2Of | construct,or |
R17656 | T23106 | T23105 | arg1Of | construct,pNF-κB-SEAP |
R17657 | T23107 | T23108 | arg1Of | Cells,were |
R17658 | T23109 | T23108 | arg2Of | serum,were |
R17659 | T23109 | T23110 | arg2Of | serum,starved |
R17660 | T23110 | T23111 | arg1Of | starved,for |
R17661 | T23112 | T23115 | arg1Of | 4,to |
R17662 | T23114 | T23113 | arg1Of | prior,hours |
R17663 | T23115 | T23114 | arg1Of | to,prior |
R17664 | T23117 | T23115 | arg2Of | hours,to |
R17665 | T23117 | T23116 | arg1Of | hours,2 |
R17666 | T23118 | T23111 | arg2Of | stimulation,for |
R17667 | T23118 | T23112 | arg1Of | stimulation,4 |
R17668 | T23118 | T23119 | arg1Of | stimulation,with |
R17669 | T23122 | T23119 | arg2Of | M-CSF,with |
R17670 | T23122 | T23120 | arg1Of | M-CSF,mouse |
R17671 | T23122 | T23121 | arg1Of | M-CSF,recombinant |
R17672 | T23122 | T23123 | arg1Of | M-CSF,( |
R17673 | T23125 | T23123 | arg2Of | ng/ml,( |
R17674 | T23125 | T23124 | arg1Of | ng/ml,100 |
R17675 | T23126 | T23123 | arg3Of | ),( |
R17676 | T23128 | T23127 | arg1Of | media,Culture |
R17677 | T23128 | T23129 | arg1Of | media,was |
R17678 | T23128 | T23130 | arg2Of | media,collected |
R17679 | T23130 | T23129 | arg2Of | collected,was |
R17680 | T23130 | T23131 | modOf | collected,to |
R17681 | T23132 | T23131 | arg1Of | measure,to |
R17682 | T23134 | T23132 | arg2Of | production,measure |
R17683 | T23134 | T23133 | arg1Of | production,SEAP |
R17684 | T23135 | T23136 | arg1Of | Data,are |
R17685 | T23135 | T23137 | arg2Of | Data,expressed |
R17686 | T23137 | T23136 | arg2Of | expressed,are |
R17687 | T23137 | T23140 | arg1Of | expressed,S.E.M |
R17688 | T23137 | T23141 | arg1Of | expressed,"," |
R17689 | T23137 | T23142 | arg1Of | expressed,for |
R17690 | T23140 | T23138 | arg1Of | S.E.M,mean |
R17691 | T23140 | T23139 | arg1Of | S.E.M,± |
R17692 | T23145 | T23142 | arg2Of | experiments,for |
R17693 | T23145 | T23143 | arg1Of | experiments,three |
R17694 | T23145 | T23144 | arg1Of | experiments,independent |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4664 | 0-131 | Sentence | denotes | M-CSF Induces NF-κB Transcriptional Activity in Human Monocyte–Derived Macrophages (MDMs) and Mouse Macrophage Cell Line, RAW 264.7 |
T4665 | 132-386 | Sentence | denotes | To determine if M-CSF induced NF-κB DNA binding in human macrophages, we performed EMSA analysis on nuclear lysates from M-CSF-treated MDMs. Similar to previous reports [11], nuclear NF-κB constitutively bound DNA in non-stimulated monocytes (Figure 1A). |
T4666 | 387-455 | Sentence | denotes | Interestingly, adding M-CSF did not alter NF-κB DNA binding by EMSA. |
T4667 | 456-763 | Sentence | denotes | In contrast, after transiently transfecting human MDMs with pNF-κB-SEAP constructs containing four NF-κB consensus binding sequences, M-CSF treatment of the transfected cells resulted in a 2.3-fold increase in SEAP release in the culture media compared to PBS (vehicle)-treated transfected MDMs (Figure 1B). |
T4668 | 764-839 | Sentence | denotes | As a control, the pTAL-SEAP construct lacking NF-κB binding sites was used. |
T4669 | 840-956 | Sentence | denotes | Cells transfected with the pTAL-SEAP construct did not produce SEAP in the absence or presence of M-CSF (Figure 1B). |
T4670 | 1987-2090 | Sentence | denotes | We next investigated whether M-CSF induced NF-κB activity in the mouse macrophage cell line, RAW 264.7. |
T4671 | 2091-2191 | Sentence | denotes | RAW 264.7 cells were transfected with either the NF-κB-SEAP reporter or control pTAL-SEAP construct. |
T4672 | 2192-2327 | Sentence | denotes | As shown in Figure 1C, M-CSF treatment of RAW 264.7 cells increased NF-κB reporter activity by 2.5-fold over that of non-treated cells. |
T4673 | 2328-2424 | Sentence | denotes | Together, our data demonstrate that M-CSF induced NF-κB transcriptional activity in macrophages. |
T22810 | 1001-1061 | Sentence | denotes | M-CSF induces NF-κB transcriptional activity in macrophages. |
T22811 | 1062-1155 | Sentence | denotes | (A) Nuclei were extracted from human MDMs treated without or with M-CSF for 15 or 30 minutes. |
T22812 | 1156-1270 | Sentence | denotes | NF-κB DNA binding activity was analyzed by EMSA Shown is a representative blot from three independent experiments. |
T22813 | 1271-1470 | Sentence | denotes | NS: non-stimulated. (B) Human MDMs transiently transfected with pTAL-SEAP or pNF-κB-SEAP constructs were treated with M-CSF in X-vivo medium and incubated for 6 hours before the collection of medium. |
T22814 | 1471-1752 | Sentence | denotes | NF-κB activity was analyzed by measuring the amount of SEAP secreted into the medium and data are expressed as fold increase of SEAP activity over that in pTAL-SEAP transfected resting cells. (C) RAW 264.7 cells were transiently transfected with pTAL-SEAP or pNF-κB-SEAP construct. |
T22815 | 1753-1860 | Sentence | denotes | Cells were serum starved for 4 hours prior to 2 hours stimulation with mouse recombinant M-CSF (100 ng/ml). |
T22816 | 1861-1916 | Sentence | denotes | Culture media was collected to measure SEAP production. |
T22817 | 1917-1984 | Sentence | denotes | Data are expressed mean ± S.E.M, for three independent experiments. |
T62 | 0-131 | Sentence | denotes | M-CSF Induces NF-κB Transcriptional Activity in Human Monocyte–Derived Macrophages (MDMs) and Mouse Macrophage Cell Line, RAW 264.7 |
T63 | 132-386 | Sentence | denotes | To determine if M-CSF induced NF-κB DNA binding in human macrophages, we performed EMSA analysis on nuclear lysates from M-CSF-treated MDMs. Similar to previous reports [11], nuclear NF-κB constitutively bound DNA in non-stimulated monocytes (Figure 1A). |
T64 | 387-455 | Sentence | denotes | Interestingly, adding M-CSF did not alter NF-κB DNA binding by EMSA. |
T65 | 456-763 | Sentence | denotes | In contrast, after transiently transfecting human MDMs with pNF-κB-SEAP constructs containing four NF-κB consensus binding sequences, M-CSF treatment of the transfected cells resulted in a 2.3-fold increase in SEAP release in the culture media compared to PBS (vehicle)-treated transfected MDMs (Figure 1B). |
T66 | 764-839 | Sentence | denotes | As a control, the pTAL-SEAP construct lacking NF-κB binding sites was used. |
T67 | 840-956 | Sentence | denotes | Cells transfected with the pTAL-SEAP construct did not produce SEAP in the absence or presence of M-CSF (Figure 1B). |
T68 | 957-1061 | Sentence | denotes | 10.1371/journal.pone.0028081.g001 Figure 1 M-CSF induces NF-κB transcriptional activity in macrophages. |
T69 | 1062-1155 | Sentence | denotes | (A) Nuclei were extracted from human MDMs treated without or with M-CSF for 15 or 30 minutes. |
T70 | 1156-1270 | Sentence | denotes | NF-κB DNA binding activity was analyzed by EMSA Shown is a representative blot from three independent experiments. |
T71 | 1271-1470 | Sentence | denotes | NS: non-stimulated. (B) Human MDMs transiently transfected with pTAL-SEAP or pNF-κB-SEAP constructs were treated with M-CSF in X-vivo medium and incubated for 6 hours before the collection of medium. |
T72 | 1471-1752 | Sentence | denotes | NF-κB activity was analyzed by measuring the amount of SEAP secreted into the medium and data are expressed as fold increase of SEAP activity over that in pTAL-SEAP transfected resting cells. (C) RAW 264.7 cells were transiently transfected with pTAL-SEAP or pNF-κB-SEAP construct. |
T73 | 1753-1860 | Sentence | denotes | Cells were serum starved for 4 hours prior to 2 hours stimulation with mouse recombinant M-CSF (100 ng/ml). |
T74 | 1861-1916 | Sentence | denotes | Culture media was collected to measure SEAP production. |
T75 | 1917-1984 | Sentence | denotes | Data are expressed mean ± S.E.M, for three independent experiments. |
T76 | 1987-2090 | Sentence | denotes | We next investigated whether M-CSF induced NF-κB activity in the mouse macrophage cell line, RAW 264.7. |
T77 | 2091-2191 | Sentence | denotes | RAW 264.7 cells were transfected with either the NF-κB-SEAP reporter or control pTAL-SEAP construct. |
T78 | 2192-2327 | Sentence | denotes | As shown in Figure 1C, M-CSF treatment of RAW 264.7 cells increased NF-κB reporter activity by 2.5-fold over that of non-treated cells. |
T79 | 2328-2424 | Sentence | denotes | Together, our data demonstrate that M-CSF induced NF-κB transcriptional activity in macrophages. |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
22216091-11073986-90609709 | 302-304 | 11073986 | denotes | 11 |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4674 | 0-5 | NNP | denotes | M-CSF |
T4675 | 6-13 | VBZ | denotes | Induces |
T4676 | 14-19 | NNP | denotes | NF-κB |
T4677 | 20-35 | NNP | denotes | Transcriptional |
T4678 | 36-44 | NNP | denotes | Activity |
T4679 | 45-47 | IN | denotes | in |
T4680 | 48-53 | NNP | denotes | Human |
T4681 | 54-62 | NNP | denotes | Monocyte |
T4682 | 63-70 | NNP | denotes | Derived |
T4683 | 71-82 | NNP | denotes | Macrophages |
T4684 | 83-84 | -LRB- | denotes | ( |
T4685 | 84-88 | NNP | denotes | MDMs |
T4686 | 88-89 | -RRB- | denotes | ) |
T4687 | 90-93 | CC | denotes | and |
T4688 | 94-99 | NNP | denotes | Mouse |
T4689 | 100-110 | NNP | denotes | Macrophage |
T4690 | 111-115 | NNP | denotes | Cell |
T4691 | 116-120 | NNP | denotes | Line |
T4692 | 120-121 | , | denotes | , |
T4693 | 122-125 | NNP | denotes | RAW |
T4694 | 126-131 | CD | denotes | 264.7 |
T4695 | 132-134 | TO | denotes | To |
T4696 | 135-144 | VB | denotes | determine |
T4697 | 145-147 | IN | denotes | if |
T4698 | 148-153 | NNP | denotes | M-CSF |
T4699 | 154-161 | VBD | denotes | induced |
T4700 | 162-167 | NNP | denotes | NF-κB |
T4701 | 168-171 | NNP | denotes | DNA |
T4702 | 172-179 | JJ | denotes | binding |
T4703 | 180-182 | IN | denotes | in |
T4704 | 183-188 | JJ | denotes | human |
T4705 | 189-200 | NNS | denotes | macrophages |
T4706 | 200-201 | , | denotes | , |
T4707 | 202-204 | PRP | denotes | we |
T4708 | 205-214 | VBD | denotes | performed |
T4709 | 215-219 | NNP | denotes | EMSA |
T4710 | 220-228 | NN | denotes | analysis |
T4711 | 229-231 | IN | denotes | on |
T4712 | 232-239 | JJ | denotes | nuclear |
T4713 | 240-247 | NNS | denotes | lysates |
T4714 | 248-252 | IN | denotes | from |
T4715 | 253-266 | JJ | denotes | M-CSF-treated |
T4716 | 267-271 | NNS | denotes | MDMs |
T4717 | 271-272 | . | denotes | . |
T4718 | 273-280 | JJ | denotes | Similar |
T4719 | 281-283 | TO | denotes | to |
T4720 | 284-292 | JJ | denotes | previous |
T4721 | 293-300 | NNS | denotes | reports |
T4722 | 301-302 | NNP | denotes | [ |
T4723 | 302-304 | CD | denotes | 11 |
T4724 | 304-305 | NNP | denotes | ] |
T4725 | 305-306 | , | denotes | , |
T4726 | 307-314 | JJ | denotes | nuclear |
T4727 | 315-320 | NN | denotes | NF-κB |
T4728 | 321-335 | RB | denotes | constitutively |
T4729 | 336-341 | VBN | denotes | bound |
T4730 | 342-345 | NN | denotes | DNA |
T4731 | 346-348 | IN | denotes | in |
T4732 | 349-363 | JJ | denotes | non-stimulated |
T4733 | 364-373 | NNS | denotes | monocytes |
T4734 | 374-375 | -LRB- | denotes | ( |
T4735 | 375-381 | NN | denotes | Figure |
T4736 | 382-384 | CD | denotes | 1A |
T4737 | 384-385 | -RRB- | denotes | ) |
T4738 | 385-386 | . | denotes | . |
T4739 | 387-400 | RB | denotes | Interestingly |
T4740 | 400-401 | , | denotes | , |
T4741 | 402-408 | VBG | denotes | adding |
T4742 | 409-414 | NNP | denotes | M-CSF |
T4743 | 415-418 | VBD | denotes | did |
T4744 | 419-422 | RB | denotes | not |
T4745 | 423-428 | VB | denotes | alter |
T4746 | 429-434 | NNP | denotes | NF-κB |
T4747 | 435-438 | NNP | denotes | DNA |
T4748 | 439-446 | JJ | denotes | binding |
T4749 | 447-449 | IN | denotes | by |
T4750 | 450-454 | NNP | denotes | EMSA |
T4751 | 454-455 | . | denotes | . |
T4752 | 456-458 | IN | denotes | In |
T4753 | 459-467 | NN | denotes | contrast |
T4754 | 467-468 | , | denotes | , |
T4755 | 469-474 | IN | denotes | after |
T4756 | 475-486 | RB | denotes | transiently |
T4757 | 487-499 | VBG | denotes | transfecting |
T4758 | 500-505 | JJ | denotes | human |
T4759 | 506-510 | NNS | denotes | MDMs |
T4760 | 511-515 | IN | denotes | with |
T4761 | 516-527 | JJ | denotes | pNF-κB-SEAP |
T4762 | 528-538 | NNS | denotes | constructs |
T4763 | 539-549 | VBG | denotes | containing |
T4764 | 550-554 | CD | denotes | four |
T4765 | 555-560 | JJ | denotes | NF-κB |
T4766 | 561-570 | NN | denotes | consensus |
T4767 | 571-578 | JJ | denotes | binding |
T4768 | 579-588 | NNS | denotes | sequences |
T4769 | 588-589 | , | denotes | , |
T4770 | 590-595 | NNP | denotes | M-CSF |
T4771 | 596-605 | NN | denotes | treatment |
T4772 | 606-608 | IN | denotes | of |
T4773 | 609-612 | DT | denotes | the |
T4774 | 613-624 | VBN | denotes | transfected |
T4775 | 625-630 | NNS | denotes | cells |
T4776 | 631-639 | VBD | denotes | resulted |
T4777 | 640-642 | IN | denotes | in |
T4778 | 643-644 | DT | denotes | a |
T4779 | 645-653 | JJ | denotes | 2.3-fold |
T4780 | 654-662 | NN | denotes | increase |
T4781 | 663-665 | IN | denotes | in |
T4782 | 666-670 | NNP | denotes | SEAP |
T4783 | 671-678 | NN | denotes | release |
T4784 | 679-681 | IN | denotes | in |
T4785 | 682-685 | DT | denotes | the |
T4786 | 686-693 | NN | denotes | culture |
T4787 | 694-699 | NNS | denotes | media |
T4788 | 700-708 | VBN | denotes | compared |
T4789 | 709-711 | TO | denotes | to |
T4790 | 712-715 | NNP | denotes | PBS |
T4791 | 716-717 | -LRB- | denotes | ( |
T4792 | 717-724 | NN | denotes | vehicle |
T4793 | 724-725 | -RRB- | denotes | ) |
T4794 | 725-726 | : | denotes | - |
T4795 | 726-733 | VBN | denotes | treated |
T4796 | 734-745 | VBN | denotes | transfected |
T4797 | 746-750 | NNS | denotes | MDMs |
T4798 | 751-752 | -LRB- | denotes | ( |
T4799 | 752-758 | NN | denotes | Figure |
T4800 | 759-761 | NN | denotes | 1B |
T4801 | 761-762 | -RRB- | denotes | ) |
T4802 | 762-763 | . | denotes | . |
T4803 | 764-766 | IN | denotes | As |
T4804 | 767-768 | DT | denotes | a |
T4805 | 769-776 | NN | denotes | control |
T4806 | 776-777 | , | denotes | , |
T4807 | 778-781 | DT | denotes | the |
T4808 | 782-791 | NNP | denotes | pTAL-SEAP |
T4809 | 792-801 | VB | denotes | construct |
T4810 | 802-809 | VBG | denotes | lacking |
T4811 | 810-815 | JJ | denotes | NF-κB |
T4812 | 816-823 | JJ | denotes | binding |
T4813 | 824-829 | NNS | denotes | sites |
T4814 | 830-833 | VBD | denotes | was |
T4815 | 834-838 | VBN | denotes | used |
T4816 | 838-839 | . | denotes | . |
T4817 | 840-845 | NNS | denotes | Cells |
T4818 | 846-857 | VBN | denotes | transfected |
T4819 | 858-862 | IN | denotes | with |
T4820 | 863-866 | DT | denotes | the |
T4821 | 867-876 | NNP | denotes | pTAL-SEAP |
T4822 | 877-886 | VBP | denotes | construct |
T4823 | 887-890 | VBD | denotes | did |
T4824 | 891-894 | RB | denotes | not |
T4825 | 895-902 | VB | denotes | produce |
T4826 | 903-907 | NNP | denotes | SEAP |
T4827 | 908-910 | IN | denotes | in |
T4828 | 911-914 | DT | denotes | the |
T4829 | 915-922 | NN | denotes | absence |
T4830 | 923-925 | CC | denotes | or |
T4831 | 926-934 | NN | denotes | presence |
T4832 | 935-937 | IN | denotes | of |
T4833 | 938-943 | NNP | denotes | M-CSF |
T4834 | 944-945 | -LRB- | denotes | ( |
T4835 | 945-951 | NNP | denotes | Figure |
T4836 | 952-954 | NNP | denotes | 1B |
T4837 | 954-955 | -RRB- | denotes | ) |
T4838 | 955-956 | . | denotes | . |
T4839 | 1987-1989 | PRP | denotes | We |
T4840 | 1990-1994 | JJ | denotes | next |
T4841 | 1995-2007 | VBD | denotes | investigated |
T4842 | 2008-2015 | IN | denotes | whether |
T4843 | 2016-2021 | NNP | denotes | M-CSF |
T4844 | 2022-2029 | VBD | denotes | induced |
T4845 | 2030-2035 | JJ | denotes | NF-κB |
T4846 | 2036-2044 | NN | denotes | activity |
T4847 | 2045-2047 | IN | denotes | in |
T4848 | 2048-2051 | DT | denotes | the |
T4849 | 2052-2057 | NN | denotes | mouse |
T4850 | 2058-2068 | NN | denotes | macrophage |
T4851 | 2069-2073 | NN | denotes | cell |
T4852 | 2074-2078 | NN | denotes | line |
T4853 | 2078-2079 | , | denotes | , |
T4854 | 2080-2083 | NNP | denotes | RAW |
T4855 | 2084-2089 | CD | denotes | 264.7 |
T4856 | 2089-2090 | . | denotes | . |
T4857 | 2091-2094 | NNP | denotes | RAW |
T4858 | 2095-2100 | CD | denotes | 264.7 |
T4859 | 2101-2106 | NNS | denotes | cells |
T4860 | 2107-2111 | VBD | denotes | were |
T4861 | 2112-2123 | VBN | denotes | transfected |
T4862 | 2124-2128 | IN | denotes | with |
T4863 | 2129-2135 | CC | denotes | either |
T4864 | 2136-2139 | DT | denotes | the |
T4865 | 2140-2150 | NNP | denotes | NF-κB-SEAP |
T4866 | 2151-2159 | NN | denotes | reporter |
T4867 | 2160-2162 | CC | denotes | or |
T4868 | 2163-2170 | NN | denotes | control |
T4869 | 2171-2180 | JJ | denotes | pTAL-SEAP |
T4870 | 2181-2190 | VBP | denotes | construct |
T4871 | 2190-2191 | . | denotes | . |
T4872 | 2192-2194 | IN | denotes | As |
T4873 | 2195-2200 | VBN | denotes | shown |
T4874 | 2201-2203 | IN | denotes | in |
T4875 | 2204-2210 | NN | denotes | Figure |
T4876 | 2211-2213 | CD | denotes | 1C |
T4877 | 2213-2214 | , | denotes | , |
T4878 | 2215-2220 | NNP | denotes | M-CSF |
T4879 | 2221-2230 | NN | denotes | treatment |
T4880 | 2231-2233 | IN | denotes | of |
T4881 | 2234-2237 | NNP | denotes | RAW |
T4882 | 2238-2243 | CD | denotes | 264.7 |
T4883 | 2244-2249 | NNS | denotes | cells |
T4884 | 2250-2259 | VBD | denotes | increased |
T4885 | 2260-2265 | JJ | denotes | NF-κB |
T4886 | 2266-2274 | NN | denotes | reporter |
T4887 | 2275-2283 | NN | denotes | activity |
T4888 | 2284-2286 | IN | denotes | by |
T4889 | 2287-2295 | CD | denotes | 2.5-fold |
T4890 | 2296-2300 | IN | denotes | over |
T4891 | 2301-2305 | DT | denotes | that |
T4892 | 2306-2308 | IN | denotes | of |
T4893 | 2309-2320 | JJ | denotes | non-treated |
T4894 | 2321-2326 | NNS | denotes | cells |
T4895 | 2326-2327 | . | denotes | . |
T4896 | 2328-2336 | RB | denotes | Together |
T4897 | 2336-2337 | , | denotes | , |
T4898 | 2338-2341 | PRP$ | denotes | our |
T4899 | 2342-2346 | NNS | denotes | data |
T4900 | 2347-2358 | VBP | denotes | demonstrate |
T4901 | 2359-2363 | IN | denotes | that |
T4902 | 2364-2369 | NNP | denotes | M-CSF |
T4903 | 2370-2377 | VBD | denotes | induced |
T4904 | 2378-2383 | NNP | denotes | NF-κB |
T4905 | 2384-2399 | JJ | denotes | transcriptional |
T4906 | 2400-2408 | NN | denotes | activity |
T4907 | 2409-2411 | IN | denotes | in |
T4908 | 2412-2423 | NNS | denotes | macrophages |
T4909 | 2423-2424 | . | denotes | . |
T22818 | 1001-1006 | NNP | denotes | M-CSF |
T22819 | 1007-1014 | VBZ | denotes | induces |
T22820 | 1015-1020 | JJ | denotes | NF-κB |
T22821 | 1021-1036 | JJ | denotes | transcriptional |
T22822 | 1037-1045 | NN | denotes | activity |
T22823 | 1046-1048 | IN | denotes | in |
T22824 | 1049-1060 | NNS | denotes | macrophages |
T22825 | 1060-1061 | . | denotes | . |
T22826 | 1062-1063 | -LRB- | denotes | ( |
T22827 | 1063-1064 | NNP | denotes | A |
T22828 | 1064-1065 | -RRB- | denotes | ) |
T22829 | 1066-1072 | NNP | denotes | Nuclei |
T22830 | 1073-1077 | VBD | denotes | were |
T22831 | 1078-1087 | VBN | denotes | extracted |
T22832 | 1088-1092 | IN | denotes | from |
T22833 | 1093-1098 | JJ | denotes | human |
T22834 | 1099-1103 | NNS | denotes | MDMs |
T22835 | 1104-1111 | VBN | denotes | treated |
T22836 | 1112-1119 | IN | denotes | without |
T22837 | 1120-1122 | CC | denotes | or |
T22838 | 1123-1127 | IN | denotes | with |
T22839 | 1128-1133 | NNP | denotes | M-CSF |
T22840 | 1134-1137 | IN | denotes | for |
T22841 | 1138-1140 | CD | denotes | 15 |
T22842 | 1141-1143 | CC | denotes | or |
T22843 | 1144-1146 | CD | denotes | 30 |
T22844 | 1147-1154 | NNS | denotes | minutes |
T22845 | 1154-1155 | . | denotes | . |
T22846 | 1156-1161 | NNP | denotes | NF-κB |
T22847 | 1162-1165 | NNP | denotes | DNA |
T22848 | 1166-1173 | JJ | denotes | binding |
T22849 | 1174-1182 | NN | denotes | activity |
T22850 | 1183-1186 | VBD | denotes | was |
T22851 | 1187-1195 | VBN | denotes | analyzed |
T22852 | 1196-1198 | IN | denotes | by |
T22853 | 1199-1203 | NNP | denotes | EMSA |
T22854 | 1204-1209 | NNP | denotes | Shown |
T22855 | 1210-1212 | VBZ | denotes | is |
T22856 | 1213-1214 | DT | denotes | a |
T22857 | 1215-1229 | JJ | denotes | representative |
T22858 | 1230-1234 | NN | denotes | blot |
T22859 | 1235-1239 | IN | denotes | from |
T22860 | 1240-1245 | CD | denotes | three |
T22861 | 1246-1257 | JJ | denotes | independent |
T22862 | 1258-1269 | NNS | denotes | experiments |
T22863 | 1269-1270 | . | denotes | . |
T22864 | 1271-1273 | NNP | denotes | NS |
T22865 | 1273-1274 | : | denotes | : |
T22866 | 1275-1289 | JJ | denotes | non-stimulated |
T22867 | 1289-1290 | . | denotes | . |
T22868 | 1291-1292 | -LRB- | denotes | ( |
T22869 | 1292-1293 | NNP | denotes | B |
T22870 | 1293-1294 | -RRB- | denotes | ) |
T22871 | 1295-1300 | NNP | denotes | Human |
T22872 | 1301-1305 | NNP | denotes | MDMs |
T22873 | 1306-1317 | RB | denotes | transiently |
T22874 | 1318-1329 | VBD | denotes | transfected |
T22875 | 1330-1334 | IN | denotes | with |
T22876 | 1335-1344 | JJ | denotes | pTAL-SEAP |
T22877 | 1345-1347 | CC | denotes | or |
T22878 | 1348-1359 | JJ | denotes | pNF-κB-SEAP |
T22879 | 1360-1370 | NNS | denotes | constructs |
T22880 | 1371-1375 | VBD | denotes | were |
T22881 | 1376-1383 | VBN | denotes | treated |
T22882 | 1384-1388 | IN | denotes | with |
T22883 | 1389-1394 | NNP | denotes | M-CSF |
T22884 | 1395-1397 | IN | denotes | in |
T22885 | 1398-1404 | NNP | denotes | X-vivo |
T22886 | 1405-1411 | NN | denotes | medium |
T22887 | 1412-1415 | CC | denotes | and |
T22888 | 1416-1425 | VBN | denotes | incubated |
T22889 | 1426-1429 | IN | denotes | for |
T22890 | 1430-1431 | CD | denotes | 6 |
T22891 | 1432-1437 | NNS | denotes | hours |
T22892 | 1438-1444 | IN | denotes | before |
T22893 | 1445-1448 | DT | denotes | the |
T22894 | 1449-1459 | NN | denotes | collection |
T22895 | 1460-1462 | IN | denotes | of |
T22896 | 1463-1469 | NN | denotes | medium |
T22897 | 1469-1470 | . | denotes | . |
T22898 | 1471-1476 | JJ | denotes | NF-κB |
T22899 | 1477-1485 | NN | denotes | activity |
T22900 | 1486-1489 | VBD | denotes | was |
T22901 | 1490-1498 | VBN | denotes | analyzed |
T22902 | 1499-1501 | IN | denotes | by |
T22903 | 1502-1511 | VBG | denotes | measuring |
T22904 | 1512-1515 | DT | denotes | the |
T22905 | 1516-1522 | NN | denotes | amount |
T22906 | 1523-1525 | IN | denotes | of |
T22907 | 1526-1530 | NNP | denotes | SEAP |
T22908 | 1531-1539 | VBD | denotes | secreted |
T22909 | 1540-1544 | IN | denotes | into |
T22910 | 1545-1548 | DT | denotes | the |
T22911 | 1549-1555 | NN | denotes | medium |
T22912 | 1556-1559 | CC | denotes | and |
T22913 | 1560-1564 | NNS | denotes | data |
T22914 | 1565-1568 | VBP | denotes | are |
T22915 | 1569-1578 | VBN | denotes | expressed |
T22916 | 1579-1581 | IN | denotes | as |
T22917 | 1582-1586 | VBP | denotes | fold |
T22918 | 1587-1595 | NN | denotes | increase |
T22919 | 1596-1598 | IN | denotes | of |
T22920 | 1599-1603 | NNP | denotes | SEAP |
T22921 | 1604-1612 | NN | denotes | activity |
T22922 | 1613-1617 | IN | denotes | over |
T22923 | 1618-1622 | DT | denotes | that |
T22924 | 1623-1625 | IN | denotes | in |
T22925 | 1626-1635 | JJ | denotes | pTAL-SEAP |
T22926 | 1636-1647 | VBN | denotes | transfected |
T22927 | 1648-1655 | VBG | denotes | resting |
T22928 | 1656-1661 | NNS | denotes | cells |
T22929 | 1661-1662 | . | denotes | . |
T22930 | 1663-1664 | -LRB- | denotes | ( |
T22931 | 1664-1665 | NNP | denotes | C |
T22932 | 1665-1666 | -RRB- | denotes | ) |
T22933 | 1667-1670 | NNP | denotes | RAW |
T22934 | 1671-1676 | CD | denotes | 264.7 |
T22935 | 1677-1682 | NNS | denotes | cells |
T22936 | 1683-1687 | VBD | denotes | were |
T22937 | 1688-1699 | RB | denotes | transiently |
T22938 | 1700-1711 | VBN | denotes | transfected |
T22939 | 1712-1716 | IN | denotes | with |
T22940 | 1717-1726 | NNP | denotes | pTAL-SEAP |
T22941 | 1727-1729 | CC | denotes | or |
T22942 | 1730-1741 | NNP | denotes | pNF-κB-SEAP |
T22943 | 1742-1751 | VBP | denotes | construct |
T22944 | 1751-1752 | . | denotes | . |
T22945 | 1753-1758 | NNS | denotes | Cells |
T22946 | 1759-1763 | VBD | denotes | were |
T22947 | 1764-1769 | JJ | denotes | serum |
T22948 | 1770-1777 | VBN | denotes | starved |
T22949 | 1778-1781 | IN | denotes | for |
T22950 | 1782-1783 | CD | denotes | 4 |
T22951 | 1784-1789 | NNS | denotes | hours |
T22952 | 1790-1795 | RB | denotes | prior |
T22953 | 1796-1798 | TO | denotes | to |
T22954 | 1799-1800 | CD | denotes | 2 |
T22955 | 1801-1806 | NNS | denotes | hours |
T22956 | 1807-1818 | NN | denotes | stimulation |
T22957 | 1819-1823 | IN | denotes | with |
T22958 | 1824-1829 | NN | denotes | mouse |
T22959 | 1830-1841 | JJ | denotes | recombinant |
T22960 | 1842-1847 | NNP | denotes | M-CSF |
T22961 | 1848-1849 | -LRB- | denotes | ( |
T22962 | 1849-1852 | CD | denotes | 100 |
T22963 | 1853-1858 | NN | denotes | ng/ml |
T22964 | 1858-1859 | -RRB- | denotes | ) |
T22965 | 1859-1860 | . | denotes | . |
T22966 | 1861-1868 | NNP | denotes | Culture |
T22967 | 1869-1874 | NNS | denotes | media |
T22968 | 1875-1878 | VBD | denotes | was |
T22969 | 1879-1888 | VBN | denotes | collected |
T22970 | 1889-1891 | TO | denotes | to |
T22971 | 1892-1899 | VB | denotes | measure |
T22972 | 1900-1904 | NNP | denotes | SEAP |
T22973 | 1905-1915 | NN | denotes | production |
T22974 | 1915-1916 | . | denotes | . |
T22975 | 1917-1921 | NNS | denotes | Data |
T22976 | 1922-1925 | VBP | denotes | are |
T22977 | 1926-1935 | VBN | denotes | expressed |
T22978 | 1936-1940 | JJ | denotes | mean |
T22979 | 1941-1942 | NN | denotes | ± |
T22980 | 1943-1948 | NNP | denotes | S.E.M |
T22981 | 1948-1949 | , | denotes | , |
T22982 | 1950-1953 | IN | denotes | for |
T22983 | 1954-1959 | CD | denotes | three |
T22984 | 1960-1971 | JJ | denotes | independent |
T22985 | 1972-1983 | NNS | denotes | experiments |
T22986 | 1983-1984 | . | denotes | . |
R3429 | T4674 | T4675 | nsubj | M-CSF,Induces |
R3430 | T4675 | T4675 | ROOT | Induces,Induces |
R3431 | T4676 | T4678 | compound | NF-κB,Activity |
R3432 | T4677 | T4678 | compound | Transcriptional,Activity |
R3433 | T4678 | T4675 | dobj | Activity,Induces |
R3434 | T4679 | T4678 | prep | in,Activity |
R3435 | T4680 | T4681 | compound | Human,Monocyte |
R3436 | T4681 | T4679 | pobj | Monocyte,in |
R3437 | T4682 | T4683 | compound | Derived,Macrophages |
R3438 | T4683 | T4678 | conj | Macrophages,Activity |
R3439 | T4684 | T4685 | punct | (,MDMs |
R3440 | T4685 | T4683 | appos | MDMs,Macrophages |
R3441 | T4686 | T4685 | punct | ),MDMs |
R3442 | T4687 | T4683 | cc | and,Macrophages |
R3443 | T4688 | T4691 | compound | Mouse,Line |
R3444 | T4689 | T4691 | compound | Macrophage,Line |
R3445 | T4690 | T4691 | compound | Cell,Line |
R3446 | T4691 | T4683 | conj | Line,Macrophages |
R3447 | T4692 | T4691 | punct | ",",Line |
R3448 | T4693 | T4691 | conj | RAW,Line |
R3449 | T4694 | T4693 | nummod | 264.7,RAW |
R3450 | T4695 | T4696 | aux | To,determine |
R3451 | T4696 | T4675 | advcl | determine,Induces |
R3452 | T4697 | T4699 | mark | if,induced |
R3453 | T4698 | T4699 | nsubj | M-CSF,induced |
R3454 | T4699 | T4708 | advcl | induced,performed |
R3455 | T4700 | T4701 | compound | NF-κB,DNA |
R3456 | T4701 | T4699 | dobj | DNA,induced |
R3457 | T4702 | T4699 | advcl | binding,induced |
R3458 | T4703 | T4702 | prep | in,binding |
R3459 | T4704 | T4705 | amod | human,macrophages |
R3460 | T4705 | T4703 | pobj | macrophages,in |
R3461 | T4706 | T4708 | punct | ",",performed |
R3462 | T4707 | T4708 | nsubj | we,performed |
R3463 | T4708 | T4675 | conj | performed,Induces |
R3464 | T4709 | T4710 | compound | EMSA,analysis |
R3465 | T4710 | T4708 | dobj | analysis,performed |
R3466 | T4711 | T4708 | prep | on,performed |
R3467 | T4712 | T4713 | amod | nuclear,lysates |
R3468 | T4713 | T4711 | pobj | lysates,on |
R3469 | T4714 | T4713 | prep | from,lysates |
R3470 | T4715 | T4716 | amod | M-CSF-treated,MDMs |
R3471 | T4716 | T4714 | pobj | MDMs,from |
R3472 | T4717 | T4708 | punct | .,performed |
R3473 | T4718 | T4718 | ROOT | Similar,Similar |
R3474 | T4719 | T4718 | prep | to,Similar |
R3475 | T4720 | T4721 | amod | previous,reports |
R3476 | T4721 | T4719 | pobj | reports,to |
R3477 | T4722 | T4724 | compound | [,] |
R3478 | T4723 | T4724 | compound | 11,] |
R3479 | T4724 | T4718 | appos | ],Similar |
R3480 | T4725 | T4724 | punct | ",",] |
R3481 | T4726 | T4727 | amod | nuclear,NF-κB |
R3482 | T4727 | T4724 | appos | NF-κB,] |
R3483 | T4728 | T4729 | advmod | constitutively,bound |
R3484 | T4729 | T4730 | amod | bound,DNA |
R3485 | T4730 | T4724 | conj | DNA,] |
R3486 | T4731 | T4730 | prep | in,DNA |
R3487 | T4732 | T4733 | amod | non-stimulated,monocytes |
R3488 | T4733 | T4731 | pobj | monocytes,in |
R3489 | T4734 | T4735 | punct | (,Figure |
R3490 | T4735 | T4733 | parataxis | Figure,monocytes |
R3491 | T4736 | T4735 | nummod | 1A,Figure |
R3492 | T4737 | T4735 | punct | ),Figure |
R3493 | T4738 | T4718 | punct | .,Similar |
R3494 | T4739 | T4745 | advmod | Interestingly,alter |
R3495 | T4740 | T4745 | punct | ",",alter |
R3496 | T4741 | T4745 | advcl | adding,alter |
R3497 | T4742 | T4741 | dobj | M-CSF,adding |
R3498 | T4743 | T4745 | aux | did,alter |
R3499 | T4744 | T4745 | neg | not,alter |
R3500 | T4745 | T4745 | ROOT | alter,alter |
R3501 | T4746 | T4747 | compound | NF-κB,DNA |
R3502 | T4747 | T4745 | dobj | DNA,alter |
R3503 | T4748 | T4747 | acl | binding,DNA |
R3504 | T4749 | T4748 | agent | by,binding |
R3505 | T4750 | T4749 | pobj | EMSA,by |
R3506 | T4751 | T4745 | punct | .,alter |
R3507 | T4752 | T4776 | prep | In,resulted |
R3508 | T4753 | T4752 | pobj | contrast,In |
R3509 | T4754 | T4776 | punct | ",",resulted |
R3510 | T4755 | T4776 | prep | after,resulted |
R3511 | T4756 | T4757 | advmod | transiently,transfecting |
R3512 | T4757 | T4755 | pcomp | transfecting,after |
R3513 | T4758 | T4759 | amod | human,MDMs |
R3514 | T4759 | T4757 | dobj | MDMs,transfecting |
R3515 | T4760 | T4757 | prep | with,transfecting |
R3516 | T4761 | T4762 | compound | pNF-κB-SEAP,constructs |
R3517 | T4762 | T4760 | pobj | constructs,with |
R3518 | T4763 | T4762 | acl | containing,constructs |
R3519 | T4764 | T4768 | nummod | four,sequences |
R3520 | T4765 | T4768 | amod | NF-κB,sequences |
R3521 | T4766 | T4768 | amod | consensus,sequences |
R3522 | T4767 | T4768 | amod | binding,sequences |
R3523 | T4768 | T4763 | dobj | sequences,containing |
R3524 | T4769 | T4768 | punct | ",",sequences |
R3525 | T4770 | T4771 | compound | M-CSF,treatment |
R3526 | T4771 | T4776 | nsubj | treatment,resulted |
R3527 | T4772 | T4771 | prep | of,treatment |
R3528 | T4773 | T4775 | det | the,cells |
R3529 | T4774 | T4775 | amod | transfected,cells |
R3530 | T4775 | T4772 | pobj | cells,of |
R3531 | T4776 | T4776 | ROOT | resulted,resulted |
R3532 | T4777 | T4776 | prep | in,resulted |
R3533 | T4778 | T4780 | det | a,increase |
R3534 | T4779 | T4780 | amod | 2.3-fold,increase |
R3535 | T4780 | T4777 | pobj | increase,in |
R3536 | T4781 | T4780 | prep | in,increase |
R3537 | T4782 | T4783 | compound | SEAP,release |
R3538 | T4783 | T4781 | pobj | release,in |
R3539 | T4784 | T4783 | prep | in,release |
R3540 | T4785 | T4787 | det | the,media |
R3541 | T4786 | T4787 | compound | culture,media |
R3542 | T4787 | T4784 | pobj | media,in |
R3543 | T4788 | T4776 | prep | compared,resulted |
R3544 | T4789 | T4788 | prep | to,compared |
R3545 | T4790 | T4789 | pobj | PBS,to |
R3546 | T4791 | T4792 | punct | (,vehicle |
R3547 | T4792 | T4790 | appos | vehicle,PBS |
R3548 | T4793 | T4790 | punct | ),PBS |
R3549 | T4794 | T4795 | punct | -,treated |
R3550 | T4795 | T4797 | amod | treated,MDMs |
R3551 | T4796 | T4797 | amod | transfected,MDMs |
R3552 | T4797 | T4789 | pobj | MDMs,to |
R3553 | T4798 | T4800 | punct | (,1B |
R3554 | T4799 | T4800 | compound | Figure,1B |
R3555 | T4800 | T4797 | appos | 1B,MDMs |
R3556 | T4801 | T4800 | punct | ),1B |
R3557 | T4802 | T4776 | punct | .,resulted |
R3558 | T4803 | T4809 | prep | As,construct |
R3559 | T4804 | T4805 | det | a,control |
R3560 | T4805 | T4803 | pobj | control,As |
R3561 | T4806 | T4809 | punct | ",",construct |
R3562 | T4807 | T4808 | det | the,pTAL-SEAP |
R3563 | T4808 | T4809 | nsubj | pTAL-SEAP,construct |
R3564 | T4809 | T4809 | ROOT | construct,construct |
R3565 | T4810 | T4809 | xcomp | lacking,construct |
R3566 | T4811 | T4813 | amod | NF-κB,sites |
R3567 | T4812 | T4813 | amod | binding,sites |
R3568 | T4813 | T4815 | nsubjpass | sites,used |
R3569 | T4814 | T4815 | auxpass | was,used |
R3570 | T4815 | T4810 | ccomp | used,lacking |
R3571 | T4816 | T4809 | punct | .,construct |
R3572 | T4817 | T4822 | nsubj | Cells,construct |
R3573 | T4818 | T4817 | acl | transfected,Cells |
R3574 | T4819 | T4818 | prep | with,transfected |
R3575 | T4820 | T4821 | det | the,pTAL-SEAP |
R3576 | T4821 | T4819 | pobj | pTAL-SEAP,with |
R3577 | T4822 | T4822 | ROOT | construct,construct |
R3578 | T4823 | T4825 | aux | did,produce |
R3579 | T4824 | T4825 | neg | not,produce |
R3580 | T4825 | T4822 | conj | produce,construct |
R3581 | T4826 | T4825 | dobj | SEAP,produce |
R3582 | T4827 | T4825 | prep | in,produce |
R3583 | T4828 | T4829 | det | the,absence |
R3584 | T4829 | T4827 | pobj | absence,in |
R3585 | T4830 | T4829 | cc | or,absence |
R3586 | T4831 | T4829 | conj | presence,absence |
R3587 | T4832 | T4829 | prep | of,absence |
R3588 | T4833 | T4832 | pobj | M-CSF,of |
R3589 | T4834 | T4836 | punct | (,1B |
R3590 | T4835 | T4836 | compound | Figure,1B |
R3591 | T4836 | T4833 | appos | 1B,M-CSF |
R3592 | T4837 | T4833 | punct | ),M-CSF |
R3593 | T4838 | T4822 | punct | .,construct |
R3594 | T4839 | T4841 | nsubj | We,investigated |
R3595 | T4840 | T4841 | advmod | next,investigated |
R3596 | T4841 | T4841 | ROOT | investigated,investigated |
R3597 | T4842 | T4844 | mark | whether,induced |
R3598 | T4843 | T4844 | nsubj | M-CSF,induced |
R3599 | T4844 | T4841 | ccomp | induced,investigated |
R3600 | T4845 | T4846 | compound | NF-κB,activity |
R3601 | T4846 | T4844 | dobj | activity,induced |
R3602 | T4847 | T4844 | prep | in,induced |
R3603 | T4848 | T4852 | det | the,line |
R3604 | T4849 | T4852 | compound | mouse,line |
R3605 | T4850 | T4852 | compound | macrophage,line |
R3606 | T4851 | T4852 | compound | cell,line |
R3607 | T4852 | T4847 | pobj | line,in |
R3608 | T4853 | T4852 | punct | ",",line |
R3609 | T4854 | T4852 | appos | RAW,line |
R3610 | T4855 | T4854 | nummod | 264.7,RAW |
R3611 | T4856 | T4841 | punct | .,investigated |
R3612 | T4857 | T4861 | nsubjpass | RAW,transfected |
R3613 | T4858 | T4859 | nummod | 264.7,cells |
R3614 | T4859 | T4861 | nsubjpass | cells,transfected |
R3615 | T4860 | T4861 | auxpass | were,transfected |
R3616 | T4861 | T4861 | ROOT | transfected,transfected |
R3617 | T4862 | T4861 | prep | with,transfected |
R3618 | T4863 | T4866 | preconj | either,reporter |
R3619 | T4864 | T4866 | det | the,reporter |
R3620 | T4865 | T4866 | compound | NF-κB-SEAP,reporter |
R3621 | T4866 | T4870 | nsubj | reporter,construct |
R3622 | T4867 | T4866 | cc | or,reporter |
R3623 | T4868 | T4866 | conj | control,reporter |
R3624 | T4869 | T4870 | amod | pTAL-SEAP,construct |
R3625 | T4870 | T4870 | ROOT | construct,construct |
R3626 | T4871 | T4870 | punct | .,construct |
R3627 | T4872 | T4873 | mark | As,shown |
R3628 | T4873 | T4884 | advcl | shown,increased |
R3629 | T4874 | T4873 | prep | in,shown |
R3630 | T4875 | T4874 | pobj | Figure,in |
R3631 | T4876 | T4875 | nummod | 1C,Figure |
R3632 | T4877 | T4875 | punct | ",",Figure |
R3633 | T4878 | T4879 | compound | M-CSF,treatment |
R3634 | T4879 | T4875 | appos | treatment,Figure |
R3635 | T4880 | T4879 | prep | of,treatment |
R3636 | T4881 | T4880 | pobj | RAW,of |
R3637 | T4882 | T4883 | nummod | 264.7,cells |
R3638 | T4883 | T4884 | nsubj | cells,increased |
R3639 | T4884 | T4884 | ROOT | increased,increased |
R3640 | T4885 | T4887 | amod | NF-κB,activity |
R3641 | T4886 | T4887 | compound | reporter,activity |
R3642 | T4887 | T4884 | dobj | activity,increased |
R3643 | T4888 | T4884 | prep | by,increased |
R3644 | T4889 | T4888 | pobj | 2.5-fold,by |
R3645 | T4890 | T4884 | prep | over,increased |
R3646 | T4891 | T4890 | pobj | that,over |
R3647 | T4892 | T4891 | prep | of,that |
R3648 | T4893 | T4894 | amod | non-treated,cells |
R3649 | T4894 | T4892 | pobj | cells,of |
R3650 | T4895 | T4884 | punct | .,increased |
R3651 | T4896 | T4900 | advmod | Together,demonstrate |
R3652 | T4897 | T4900 | punct | ",",demonstrate |
R3653 | T4898 | T4899 | poss | our,data |
R3654 | T4899 | T4900 | nsubj | data,demonstrate |
R3655 | T4900 | T4900 | ROOT | demonstrate,demonstrate |
R3656 | T4901 | T4903 | mark | that,induced |
R3657 | T4902 | T4903 | nsubj | M-CSF,induced |
R3658 | T4903 | T4900 | ccomp | induced,demonstrate |
R3659 | T4904 | T4906 | compound | NF-κB,activity |
R3660 | T4905 | T4906 | compound | transcriptional,activity |
R3661 | T4906 | T4903 | dobj | activity,induced |
R3662 | T4907 | T4906 | prep | in,activity |
R3663 | T4908 | T4907 | pobj | macrophages,in |
R3664 | T4909 | T4900 | punct | .,demonstrate |
R17362 | T22818 | T22819 | nsubj | M-CSF,induces |
R17363 | T22819 | T22819 | ROOT | induces,induces |
R17364 | T22820 | T22822 | amod | NF-κB,activity |
R17365 | T22821 | T22822 | amod | transcriptional,activity |
R17366 | T22822 | T22819 | dobj | activity,induces |
R17367 | T22823 | T22822 | prep | in,activity |
R17368 | T22824 | T22823 | pobj | macrophages,in |
R17369 | T22825 | T22819 | punct | .,induces |
R17370 | T22826 | T22831 | punct | (,extracted |
R17371 | T22827 | T22829 | nmod | A,Nuclei |
R17372 | T22828 | T22827 | punct | ),A |
R17373 | T22829 | T22831 | nsubjpass | Nuclei,extracted |
R17374 | T22830 | T22831 | auxpass | were,extracted |
R17375 | T22831 | T22831 | ROOT | extracted,extracted |
R17376 | T22832 | T22831 | prep | from,extracted |
R17377 | T22833 | T22834 | amod | human,MDMs |
R17378 | T22834 | T22832 | pobj | MDMs,from |
R17379 | T22835 | T22831 | conj | treated,extracted |
R17380 | T22836 | T22835 | prep | without,treated |
R17381 | T22837 | T22836 | cc | or,without |
R17382 | T22838 | T22836 | conj | with,without |
R17383 | T22839 | T22838 | pobj | M-CSF,with |
R17384 | T22840 | T22835 | prep | for,treated |
R17385 | T22841 | T22844 | nummod | 15,minutes |
R17386 | T22842 | T22841 | cc | or,15 |
R17387 | T22843 | T22841 | conj | 30,15 |
R17388 | T22844 | T22840 | pobj | minutes,for |
R17389 | T22845 | T22831 | punct | .,extracted |
R17390 | T22846 | T22847 | compound | NF-κB,DNA |
R17391 | T22847 | T22849 | compound | DNA,activity |
R17392 | T22848 | T22849 | amod | binding,activity |
R17393 | T22849 | T22851 | nsubjpass | activity,analyzed |
R17394 | T22850 | T22851 | auxpass | was,analyzed |
R17395 | T22851 | T22851 | ROOT | analyzed,analyzed |
R17396 | T22852 | T22851 | agent | by,analyzed |
R17397 | T22853 | T22854 | compound | EMSA,Shown |
R17398 | T22854 | T22852 | pobj | Shown,by |
R17399 | T22855 | T22851 | conj | is,analyzed |
R17400 | T22856 | T22858 | det | a,blot |
R17401 | T22857 | T22858 | amod | representative,blot |
R17402 | T22858 | T22855 | attr | blot,is |
R17403 | T22859 | T22858 | prep | from,blot |
R17404 | T22860 | T22862 | nummod | three,experiments |
R17405 | T22861 | T22862 | amod | independent,experiments |
R17406 | T22862 | T22859 | pobj | experiments,from |
R17407 | T22863 | T22851 | punct | .,analyzed |
R17408 | T22864 | T22864 | ROOT | NS,NS |
R17409 | T22865 | T22864 | punct | :,NS |
R17410 | T22866 | T22864 | acl | non-stimulated,NS |
R17411 | T22867 | T22864 | punct | .,NS |
R17412 | T22868 | T22874 | punct | (,transfected |
R17413 | T22869 | T22874 | dep | B,transfected |
R17414 | T22870 | T22869 | punct | ),B |
R17415 | T22871 | T22872 | compound | Human,MDMs |
R17416 | T22872 | T22874 | nsubj | MDMs,transfected |
R17417 | T22873 | T22874 | advmod | transiently,transfected |
R17418 | T22874 | T22874 | ROOT | transfected,transfected |
R17419 | T22875 | T22874 | prep | with,transfected |
R17420 | T22876 | T22879 | amod | pTAL-SEAP,constructs |
R17421 | T22877 | T22876 | cc | or,pTAL-SEAP |
R17422 | T22878 | T22876 | conj | pNF-κB-SEAP,pTAL-SEAP |
R17423 | T22879 | T22875 | pobj | constructs,with |
R17424 | T22880 | T22881 | auxpass | were,treated |
R17425 | T22881 | T22874 | dep | treated,transfected |
R17426 | T22882 | T22881 | prep | with,treated |
R17427 | T22883 | T22882 | pobj | M-CSF,with |
R17428 | T22884 | T22883 | prep | in,M-CSF |
R17429 | T22885 | T22886 | compound | X-vivo,medium |
R17430 | T22886 | T22884 | pobj | medium,in |
R17431 | T22887 | T22881 | cc | and,treated |
R17432 | T22888 | T22881 | conj | incubated,treated |
R17433 | T22889 | T22888 | prep | for,incubated |
R17434 | T22890 | T22891 | nummod | 6,hours |
R17435 | T22891 | T22889 | pobj | hours,for |
R17436 | T22892 | T22888 | advmod | before,incubated |
R17437 | T22893 | T22894 | det | the,collection |
R17438 | T22894 | T22892 | pobj | collection,before |
R17439 | T22895 | T22894 | prep | of,collection |
R17440 | T22896 | T22895 | pobj | medium,of |
R17441 | T22897 | T22874 | punct | .,transfected |
R17442 | T22898 | T22899 | amod | NF-κB,activity |
R17443 | T22899 | T22901 | nsubjpass | activity,analyzed |
R17444 | T22900 | T22901 | auxpass | was,analyzed |
R17445 | T22901 | T22901 | ROOT | analyzed,analyzed |
R17446 | T22902 | T22901 | prep | by,analyzed |
R17447 | T22903 | T22902 | pcomp | measuring,by |
R17448 | T22904 | T22905 | det | the,amount |
R17449 | T22905 | T22903 | dobj | amount,measuring |
R17450 | T22906 | T22905 | prep | of,amount |
R17451 | T22907 | T22906 | pobj | SEAP,of |
R17452 | T22908 | T22901 | conj | secreted,analyzed |
R17453 | T22909 | T22908 | prep | into,secreted |
R17454 | T22910 | T22911 | det | the,medium |
R17455 | T22911 | T22909 | pobj | medium,into |
R17456 | T22912 | T22911 | cc | and,medium |
R17457 | T22913 | T22911 | conj | data,medium |
R17458 | T22914 | T22915 | auxpass | are,expressed |
R17459 | T22915 | T22915 | ROOT | expressed,expressed |
R17460 | T22916 | T22915 | prep | as,expressed |
R17461 | T22917 | T22918 | compound | fold,increase |
R17462 | T22918 | T22916 | pobj | increase,as |
R17463 | T22919 | T22918 | prep | of,increase |
R17464 | T22920 | T22921 | compound | SEAP,activity |
R17465 | T22921 | T22919 | pobj | activity,of |
R17466 | T22922 | T22921 | prep | over,activity |
R17467 | T22923 | T22922 | pobj | that,over |
R17468 | T22924 | T22921 | prep | in,activity |
R17469 | T22925 | T22928 | amod | pTAL-SEAP,cells |
R17470 | T22926 | T22928 | amod | transfected,cells |
R17471 | T22927 | T22928 | amod | resting,cells |
R17472 | T22928 | T22924 | pobj | cells,in |
R17473 | T22929 | T22901 | punct | .,analyzed |
R17474 | T22930 | T22933 | punct | (,RAW |
R17475 | T22931 | T22933 | nmod | C,RAW |
R17476 | T22932 | T22933 | punct | ),RAW |
R17477 | T22933 | T22938 | nsubjpass | RAW,transfected |
R17478 | T22934 | T22935 | nummod | 264.7,cells |
R17479 | T22935 | T22938 | nsubjpass | cells,transfected |
R17480 | T22936 | T22938 | auxpass | were,transfected |
R17481 | T22937 | T22938 | advmod | transiently,transfected |
R17482 | T22938 | T22938 | ROOT | transfected,transfected |
R17483 | T22939 | T22938 | prep | with,transfected |
R17484 | T22940 | T22939 | pobj | pTAL-SEAP,with |
R17485 | T22941 | T22940 | cc | or,pTAL-SEAP |
R17486 | T22942 | T22940 | conj | pNF-κB-SEAP,pTAL-SEAP |
R17487 | T22943 | T22938 | conj | construct,transfected |
R17488 | T22944 | T22938 | punct | .,transfected |
R17489 | T22945 | T22948 | nsubjpass | Cells,starved |
R17490 | T22946 | T22948 | auxpass | were,starved |
R17491 | T22947 | T22948 | advmod | serum,starved |
R17492 | T22948 | T22948 | ROOT | starved,starved |
R17493 | T22949 | T22948 | prep | for,starved |
R17494 | T22950 | T22951 | nummod | 4,hours |
R17495 | T22951 | T22949 | pobj | hours,for |
R17496 | T22952 | T22948 | advmod | prior,starved |
R17497 | T22953 | T22952 | prep | to,prior |
R17498 | T22954 | T22955 | nummod | 2,hours |
R17499 | T22955 | T22953 | pobj | hours,to |
R17500 | T22956 | T22948 | advcl | stimulation,starved |
R17501 | T22957 | T22956 | prep | with,stimulation |
R17502 | T22958 | T22960 | amod | mouse,M-CSF |
R17503 | T22959 | T22960 | amod | recombinant,M-CSF |
R17504 | T22960 | T22957 | pobj | M-CSF,with |
R17505 | T22961 | T22963 | punct | (,ng/ml |
R17506 | T22962 | T22963 | nummod | 100,ng/ml |
R17507 | T22963 | T22960 | appos | ng/ml,M-CSF |
R17508 | T22964 | T22963 | punct | ),ng/ml |
R17509 | T22965 | T22948 | punct | .,starved |
R17510 | T22966 | T22967 | compound | Culture,media |
R17511 | T22967 | T22969 | nsubjpass | media,collected |
R17512 | T22968 | T22969 | auxpass | was,collected |
R17513 | T22969 | T22969 | ROOT | collected,collected |
R17514 | T22970 | T22971 | aux | to,measure |
R17515 | T22971 | T22969 | xcomp | measure,collected |
R17516 | T22972 | T22973 | compound | SEAP,production |
R17517 | T22973 | T22971 | dobj | production,measure |
R17518 | T22974 | T22969 | punct | .,collected |
R17519 | T22975 | T22977 | nsubjpass | Data,expressed |
R17520 | T22976 | T22977 | auxpass | are,expressed |
R17521 | T22977 | T22977 | ROOT | expressed,expressed |
R17522 | T22978 | T22980 | amod | mean,S.E.M |
R17523 | T22979 | T22980 | compound | ±,S.E.M |
R17524 | T22980 | T22977 | dobj | S.E.M,expressed |
R17525 | T22981 | T22977 | punct | ",",expressed |
R17526 | T22982 | T22977 | prep | for,expressed |
R17527 | T22983 | T22985 | nummod | three,experiments |
R17528 | T22984 | T22985 | amod | independent,experiments |
R17529 | T22985 | T22982 | pobj | experiments,for |
R17530 | T22986 | T22977 | punct | .,expressed |
test2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4653 | 0-5 | Protein | denotes | M-CSF |
T4654 | 148-153 | Protein | denotes | M-CSF |
T4655 | 253-258 | Protein | denotes | M-CSF |
T4656 | 409-414 | Protein | denotes | M-CSF |
T4657 | 590-595 | Protein | denotes | M-CSF |
T4658 | 938-943 | Protein | denotes | M-CSF |
T4659 | 2016-2021 | Protein | denotes | M-CSF |
T4660 | 2215-2220 | Protein | denotes | M-CSF |
T4661 | 2250-2259 | Positive_regulation | denotes | increased |
T4662 | 2260-2265 | Protein | denotes | NF-κB |
T4663 | 2364-2369 | Protein | denotes | M-CSF |
T22805 | 1001-1006 | Protein | denotes | M-CSF |
T22806 | 1128-1133 | Protein | denotes | M-CSF |
T22807 | 1389-1394 | Protein | denotes | M-CSF |
T22808 | 1842-1847 | Protein | denotes | M-CSF |
R3428 | T4660 | T4661 | causeOf | M-CSF,increased |