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PMC:3218875 / 5154-5879 JSONTXT

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bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T3087 724-725 . denotes .
T3086 717-724 NN denotes disease
T3085 713-716 DT denotes the
T3084 710-712 IN denotes of
T3083 697-709 NN denotes pathogenesis
T3082 693-696 DT denotes the
T3081 690-692 IN denotes in
T3080 680-689 JJ denotes important
T3079 674-679 VBG denotes being
T3078 671-673 IN denotes as
T3077 658-670 NN denotes inflammation
T3076 644-657 JJ denotes TLR-dependent
T3075 635-643 VB denotes identify
T3074 627-634 RB denotes clearly
T3073 616-626 VBG denotes signalling
T3072 612-615 NNP denotes TLR
T3071 606-611 VB denotes block
T3070 603-605 TO denotes to
T3069 592-602 NNS denotes strategies
T3068 589-591 CC denotes or
T3067 584-588 NNS denotes mice
T3066 575-583 NN denotes knockout
T3065 571-574 NNP denotes TLR
T3064 565-570 VBG denotes using
T3063 558-564 NNS denotes models
T3062 551-557 NN denotes animal
T3061 549-550 , denotes ,
T3060 541-549 RB denotes Moreover
T3059 539-540 . denotes .
T3058 531-539 NNS denotes patients
T3057 528-530 NNP denotes RA
T3056 525-527 IN denotes of
T3055 518-524 NNS denotes joints
T3054 509-517 JJ denotes inflamed
T3053 505-508 DT denotes the
T3052 498-504 IN denotes within
T3051 490-497 JJ denotes present
T3050 486-489 VBP denotes are
T3049 478-485 NNS denotes ligands
T3048 467-477 JJ denotes endogenous
T3047 459-466 JJ denotes various
T3046 455-458 CC denotes and
T3045 447-454 NNS denotes tissues
T3044 438-446 JJ denotes synovial
T3043 435-437 NNP denotes RA
T3042 432-434 IN denotes in
T3041 422-431 VBN denotes expressed
T3040 418-421 VBP denotes are
T3039 413-417 NNS denotes TLRs
T3038 411-412 . denotes .
T3037 410-411 -RRB- denotes )
T3036 409-410 NNP denotes ]
T3035 404-409 CD denotes 14,15
T3034 403-404 NNP denotes [
T3033 400-402 IN denotes in
T3032 391-399 VBN denotes reviewed
T3031 390-391 -LRB- denotes (
T3030 377-389 NN denotes inflammation
T3029 369-376 JJ denotes sterile
T3028 359-368 JJ denotes so-called
T3027 350-358 VBG denotes inducing
T3026 345-349 NNS denotes TLRs
T3025 342-344 IN denotes of
T3024 331-341 NNS denotes activators
T3023 321-330 NN denotes candidate
T3022 318-320 IN denotes as
T3021 309-317 VBN denotes reported
T3020 304-308 VBN denotes been
T3019 299-303 VB denotes have
T3018 297-298 : denotes -
T3017 291-296 NNS denotes cells
T3016 287-290 CC denotes and
T3015 279-286 NNS denotes tissues
T3014 274-278 NN denotes host
T3013 269-273 IN denotes from
T3012 261-268 VBN denotes derived
T3011 252-260 NNS denotes proteins
T3010 249-251 IN denotes of
T3009 243-248 NN denotes group
T3008 241-242 DT denotes a
T3007 239-240 : denotes -
T3006 231-238 NNS denotes ligands
T3005 220-230 JJ denotes endogenous
T3004 217-219 IN denotes of
T3003 210-216 NN denotes number
T3002 199-209 VBG denotes increasing
T3001 196-198 DT denotes an
T3000 194-195 , denotes ,
T2999 187-194 NNS denotes ligands
T2998 177-186 JJ denotes microbial
T2997 174-176 TO denotes to
T2996 165-173 NN denotes addition
T2995 162-164 IN denotes In
T2994 160-161 . denotes .
T2993 158-160 NNP denotes RA
T2992 155-157 IN denotes in
T2991 142-154 NN denotes inflammation
T2990 126-141 JJ denotes NF-κB-dependent
T2989 117-125 VBG denotes inducing
T2988 113-116 IN denotes for
T2987 102-112 NNS denotes candidates
T2986 92-101 JJ denotes potential
T2985 88-91 VBP denotes are
T2984 84-87 CC denotes and
T2983 75-83 NNS denotes diseases
T2982 64-74 JJ denotes autoimmune
T2981 61-63 IN denotes of
T2980 53-60 NN denotes variety
T2979 51-52 DT denotes a
T2978 48-50 IN denotes in
T2977 37-47 VBN denotes implicated
T2976 32-36 VBN denotes been
T2975 27-31 VBP denotes have
T2974 25-26 -RRB- denotes )
T2973 21-25 NNS denotes TLRs
T2972 20-21 -LRB- denotes (
T2971 10-19 NNS denotes receptors
T2970 0-9 JJ denotes Toll-like
R2308 T2970 T2971 amod Toll-like,receptors
R2310 T2971 T2977 nsubjpass receptors,implicated
R2311 T2972 T2971 punct (,receptors
R2312 T2973 T2971 appos TLRs,receptors
R2313 T2974 T2971 punct ),receptors
R2315 T2975 T2977 aux have,implicated
R2316 T2976 T2977 auxpass been,implicated
R2317 T2977 T2977 ROOT implicated,implicated
R2319 T2978 T2977 prep in,implicated
R2320 T2979 T2980 det a,variety
R2322 T2980 T2978 pobj variety,in
R2323 T2981 T2980 prep of,variety
R2324 T2982 T2983 amod autoimmune,diseases
R2325 T2983 T2981 pobj diseases,of
R2326 T2984 T2977 cc and,implicated
R2327 T2985 T2977 conj are,implicated
R2329 T2986 T2987 amod potential,candidates
R2330 T2987 T2985 attr candidates,are
R2331 T2988 T2987 prep for,candidates
R2332 T2989 T2988 pcomp inducing,for
R2334 T2990 T2991 amod NF-κB-dependent,inflammation
R2335 T2991 T2989 dobj inflammation,inducing
R2337 T2992 T2991 prep in,inflammation
R2338 T2993 T2992 pobj RA,in
R2339 T2994 T2977 punct .,implicated
R2340 T2995 T3021 prep In,reported
R2342 T2996 T2995 pobj addition,In
R2343 T2997 T2996 prep to,addition
R2344 T2998 T2999 amod microbial,ligands
R2346 T2999 T2997 pobj ligands,to
R2347 T3000 T2999 punct ",",ligands
R2349 T3001 T3003 det an,number
R2350 T3002 T3003 amod increasing,number
R2351 T3003 T2999 appos number,ligands
R2353 T3004 T3003 prep of,number
R2354 T3005 T3006 amod endogenous,ligands
R2355 T3006 T3004 pobj ligands,of
R2357 T3007 T3006 punct -,ligands
R2358 T3008 T3009 det a,group
R2359 T3009 T3003 conj group,number
R2361 T3010 T3009 prep of,group
R2362 T3011 T3010 pobj proteins,of
R2363 T3012 T3011 acl derived,proteins
R2365 T3013 T3012 prep from,derived
R2366 T3014 T3015 compound host,tissues
R2367 T3015 T3013 pobj tissues,from
R2369 T3016 T3015 cc and,tissues
R2370 T3017 T3015 conj cells,tissues
R2371 T3018 T3021 punct -,reported
R2373 T3019 T3021 aux have,reported
R2376 T3020 T3021 auxpass been,reported
R2377 T3021 T3021 ROOT reported,reported
R2378 T3022 T3021 prep as,reported
R2379 T3023 T3024 compound candidate,activators
R2381 T3024 T3022 pobj activators,as
R2382 T3025 T3024 prep of,activators
R2383 T3026 T3025 pobj TLRs,of
R2384 T3027 T3024 acl inducing,activators
R2386 T3028 T3030 amod so-called,inflammation
R2388 T3029 T3030 amod sterile,inflammation
R2389 T3030 T3027 dobj inflammation,inducing
R2390 T3031 T3030 punct (,inflammation
R2392 T3032 T3030 acl reviewed,inflammation
R2394 T3033 T3032 prep in,reviewed
R2396 T3034 T3033 pobj [,in
R2397 T3035 T3036 nummod "14,15",]
R2399 T3036 T3034 appos ],[
R2401 T3037 T3034 punct ),[
R2403 T3038 T3021 punct .,reported
R2404 T3039 T3041 nsubjpass TLRs,expressed
R2405 T3040 T3041 auxpass are,expressed
R2407 T3041 T3041 ROOT expressed,expressed
R2408 T3042 T3041 prep in,expressed
R2409 T3043 T3045 compound RA,tissues
R2411 T3044 T3045 compound synovial,tissues
R2412 T3045 T3042 pobj tissues,in
R2414 T3046 T3045 cc and,tissues
R2415 T3047 T3049 amod various,ligands
R2416 T3048 T3049 amod endogenous,ligands
R2418 T3049 T3045 conj ligands,tissues
R2419 T3050 T3041 conj are,expressed
R2421 T3051 T3050 acomp present,are
R2422 T3052 T3050 prep within,are
R2423 T3053 T3055 det the,joints
R2424 T3054 T3055 amod inflamed,joints
R2426 T3055 T3052 pobj joints,within
R2427 T3056 T3055 prep of,joints
R2428 T3057 T3058 compound RA,patients
R2429 T3058 T3056 pobj patients,of
R2430 T3059 T3041 punct .,expressed
R2431 T3060 T3075 advmod Moreover,identify
R2433 T3061 T3075 punct ",",identify
R2434 T3062 T3063 compound animal,models
R2435 T3063 T3075 nsubj models,identify
R2437 T3064 T3063 acl using,models
R2438 T3065 T3067 compound TLR,mice
R2439 T3066 T3067 compound knockout,mice
R2441 T3067 T3064 dobj mice,using
R2442 T3068 T3067 cc or,mice
R2443 T3069 T3067 conj strategies,mice
R2445 T3070 T3071 aux to,block
R2446 T3071 T3064 xcomp block,using
R2447 T3072 T3071 dobj TLR,block
R2448 T3073 T3064 conj signalling,using
R2450 T3074 T3075 advmod clearly,identify
R2451 T3075 T3075 ROOT identify,identify
R2452 T3076 T3077 amod TLR-dependent,inflammation
R2454 T3077 T3075 dobj inflammation,identify
R2455 T3078 T3075 prep as,identify
R2456 T3079 T3078 pcomp being,as
R2458 T3080 T3079 acomp important,being
R2459 T3081 T3079 prep in,being
R2460 T3082 T3083 det the,pathogenesis
R2462 T3083 T3081 pobj pathogenesis,in
R2463 T3084 T3083 prep of,pathogenesis
R2464 T3085 T3086 det the,disease
R2466 T3086 T3084 pobj disease,of
R2467 T3087 T3075 punct .,identify

2_test

Id Subject Object Predicate Lexical cue
21639951-19772831-4289441 404-406 19772831 denotes 14
21639951-20629986-4289442 407-409 20629986 denotes 15

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T2311 717-724 NN denotes disease
T2310 713-716 DT denotes the
T2309 710-712 IN denotes of
T2308 697-709 NN denotes pathogenesis
T2307 693-696 DT denotes the
T2306 690-692 IN denotes in
T2305 680-689 JJ denotes important
T2304 674-679 VB denotes being
T2303 671-673 IN denotes as
T2302 658-670 NN denotes inflammation
T2301 644-657 JJ denotes TLR-dependent
T2300 635-643 VB denotes identify
T2299 627-634 RB denotes clearly
T2298 616-626 NN denotes signalling
T2297 612-615 NN denotes TLR
T2296 606-611 VB denotes block
T2295 603-605 TO denotes to
T2294 592-602 NN denotes strategies
T2293 589-591 CC denotes or
T2292 584-588 NN denotes mice
T2291 575-583 NN denotes knockout
T2290 571-574 NN denotes TLR
T2289 565-570 VB denotes using
T2288 558-564 NN denotes models
T2287 551-557 NN denotes animal
T2286 549-550 -COMMA- denotes ,
T2285 541-549 RB denotes Moreover
T2284 531-539 NN denotes patients
T2283 528-530 NN denotes RA
T2282 525-527 IN denotes of
T2281 518-524 NN denotes joints
T2280 509-517 JJ denotes inflamed
T2279 505-508 DT denotes the
T2278 498-504 IN denotes within
T2277 490-497 JJ denotes present
T2276 486-489 VB denotes are
T2275 478-485 NN denotes ligands
T2274 467-477 JJ denotes endogenous
T2273 459-466 JJ denotes various
T2272 455-458 CC denotes and
T2237 249-251 IN denotes of
T2236 243-248 NN denotes group
T2235 241-242 DT denotes a
T2234 239-240 -COLON- denotes -
T2233 231-238 NN denotes ligands
T2232 220-230 JJ denotes endogenous
T2231 217-219 IN denotes of
T2230 210-216 NN denotes number
T2229 199-209 VB denotes increasing
T2228 196-198 DT denotes an
T2227 194-195 -COMMA- denotes ,
T2226 187-194 NN denotes ligands
T2225 177-186 JJ denotes microbial
T2224 174-176 TO denotes to
T2223 165-173 NN denotes addition
T2222 162-164 IN denotes In
T2221 158-160 NN denotes RA
T2220 155-157 IN denotes in
T2219 142-154 NN denotes inflammation
T2218 126-141 JJ denotes NF-κB-dependent
T2217 117-125 VB denotes inducing
T2216 113-116 IN denotes for
T2215 102-112 NN denotes candidates
T2214 92-101 JJ denotes potential
T2213 88-91 VB denotes are
T2212 84-87 CC denotes and
T2211 75-83 NN denotes diseases
T2210 64-74 JJ denotes autoimmune
T2209 61-63 IN denotes of
T2208 53-60 NN denotes variety
T2207 51-52 DT denotes a
T2206 48-50 IN denotes in
T2205 37-47 VB denotes implicated
T2204 32-36 VB denotes been
T2203 27-31 VB denotes have
T2202 25-26 -RRB- denotes )
T2201 21-25 NN denotes TLRs
T2200 20-21 -LRB- denotes (
T2199 10-19 NN denotes receptors
T2198 0-9 JJ denotes Toll-like
T2271 447-454 NN denotes tissues
T2270 438-446 JJ denotes synovial
T2269 435-437 NN denotes RA
T2268 432-434 IN denotes in
T2267 422-431 VB denotes expressed
T2266 418-421 VB denotes are
T2265 413-417 NN denotes TLRs
T2264 410-411 -RRB- denotes )
T2263 409-410 -RRB- denotes ]
T2262 404-409 CD denotes 14,15
T2261 403-404 -LRB- denotes [
T2260 400-402 IN denotes in
T2259 391-399 VB denotes reviewed
T2258 390-391 -LRB- denotes (
T2257 377-389 NN denotes inflammation
T2256 369-376 JJ denotes sterile
T2255 359-368 JJ denotes so-called
T2254 350-358 VB denotes inducing
T2253 345-349 NN denotes TLRs
T2252 342-344 IN denotes of
T2251 331-341 NN denotes activators
T2250 321-330 NN denotes candidate
T2249 318-320 IN denotes as
T2248 309-317 VB denotes reported
T2247 304-308 VB denotes been
T2246 299-303 VB denotes have
T2245 297-298 -COLON- denotes -
T2244 291-296 NN denotes cells
T2243 287-290 CC denotes and
T2242 279-286 NN denotes tissues
T2241 274-278 NN denotes host
T2240 269-273 IN denotes from
T2239 261-268 VB denotes derived
T2238 252-260 NN denotes proteins
R1681 T2199 T2198 arg1Of receptors,Toll-like
R1682 T2199 T2200 arg1Of receptors,(
R1683 T2199 T2203 arg1Of receptors,have
R1684 T2199 T2204 arg1Of receptors,been
R1685 T2199 T2205 arg2Of receptors,implicated
R1686 T2199 T2213 arg1Of receptors,are
R1687 T2201 T2200 arg2Of TLRs,(
R1688 T2202 T2200 arg3Of ),(
R1689 T2205 T2203 arg2Of implicated,have
R1690 T2205 T2204 arg2Of implicated,been
R1691 T2205 T2206 arg1Of implicated,in
R1692 T2205 T2212 arg1Of implicated,and
R1693 T2208 T2206 arg2Of variety,in
R1694 T2208 T2207 arg1Of variety,a
R1695 T2208 T2209 arg1Of variety,of
R1696 T2211 T2209 arg2Of diseases,of
R1697 T2211 T2210 arg1Of diseases,autoimmune
R1698 T2213 T2212 arg2Of are,and
R1699 T2215 T2213 arg2Of candidates,are
R1700 T2215 T2214 arg1Of candidates,potential
R1701 T2215 T2216 arg1Of candidates,for
R1702 T2217 T2216 arg2Of inducing,for
R1703 T2217 T2220 arg1Of inducing,in
R1704 T2219 T2217 arg2Of inflammation,inducing
R1705 T2219 T2218 arg1Of inflammation,NF-κB-dependent
R1706 T2221 T2220 arg2Of RA,in
R1707 T2223 T2222 arg2Of addition,In
R1708 T2223 T2224 arg1Of addition,to
R1709 T2226 T2224 arg2Of ligands,to
R1710 T2226 T2225 arg1Of ligands,microbial
R1711 T2230 T2228 arg1Of number,an
R1712 T2230 T2229 arg1Of number,increasing
R1713 T2230 T2231 arg1Of number,of
R1714 T2230 T2234 arg1Of number,-
R1715 T2230 T2246 arg1Of number,have
R1716 T2230 T2247 arg1Of number,been
R1717 T2230 T2248 arg2Of number,reported
R1718 T2233 T2231 arg2Of ligands,of
R1719 T2233 T2232 arg1Of ligands,endogenous
R1720 T2236 T2234 arg2Of group,-
R1721 T2236 T2235 arg1Of group,a
R1722 T2236 T2237 arg1Of group,of
R1723 T2238 T2237 arg2Of proteins,of
R1724 T2238 T2239 arg2Of proteins,derived
R1725 T2239 T2240 arg1Of derived,from
R1726 T2242 T2241 arg1Of tissues,host
R1727 T2242 T2243 arg1Of tissues,and
R1728 T2243 T2240 arg2Of and,from
R1729 T2244 T2243 arg2Of cells,and
R1730 T2244 T2245 arg1Of cells,-
R1731 T2248 T2222 arg1Of reported,In
R1732 T2248 T2227 arg1Of reported,","
R1733 T2248 T2246 arg2Of reported,have
R1734 T2248 T2247 arg2Of reported,been
R1735 T2248 T2249 arg1Of reported,as
R1736 T2251 T2249 arg2Of activators,as
R1737 T2251 T2250 arg1Of activators,candidate
R1738 T2251 T2252 arg1Of activators,of
R1739 T2253 T2252 arg2Of TLRs,of
R1740 T2253 T2254 arg1Of TLRs,inducing
R1741 T2257 T2254 arg2Of inflammation,inducing
R1742 T2257 T2255 arg1Of inflammation,so-called
R1743 T2257 T2256 arg1Of inflammation,sterile
R1744 T2257 T2258 arg1Of inflammation,(
R1745 T2259 T2258 arg2Of reviewed,(
R1746 T2259 T2260 arg1Of reviewed,in
R1747 T2259 T2261 arg1Of reviewed,[
R1748 T2262 T2261 arg2Of "14,15",[
R1749 T2263 T2261 arg3Of ],[
R1750 T2264 T2258 arg3Of ),(
R1751 T2265 T2266 arg1Of TLRs,are
R1752 T2265 T2267 arg2Of TLRs,expressed
R1753 T2267 T2266 arg2Of expressed,are
R1754 T2267 T2268 arg1Of expressed,in
R1755 T2269 T2268 arg2Of RA,in
R1756 T2271 T2270 arg1Of tissues,synovial
R1757 T2271 T2272 arg1Of tissues,and
R1758 T2272 T2276 arg1Of and,are
R1759 T2272 T2277 arg1Of and,present
R1760 T2275 T2272 arg2Of ligands,and
R1761 T2275 T2273 arg1Of ligands,various
R1762 T2275 T2274 arg1Of ligands,endogenous
R1763 T2276 T2266 modOf are,are
R1764 T2277 T2276 arg2Of present,are
R1765 T2277 T2278 arg1Of present,within
R1766 T2281 T2278 arg2Of joints,within
R1767 T2281 T2279 arg1Of joints,the
R1768 T2281 T2280 arg1Of joints,inflamed
R1769 T2281 T2282 arg1Of joints,of
R1770 T2284 T2282 arg2Of patients,of
R1771 T2284 T2283 arg1Of patients,RA
R1772 T2288 T2287 arg1Of models,animal
R1773 T2288 T2289 arg1Of models,using
R1774 T2288 T2300 arg1Of models,identify
R1775 T2292 T2290 arg1Of mice,TLR
R1776 T2292 T2291 arg1Of mice,knockout
R1777 T2292 T2293 arg1Of mice,or
R1778 T2293 T2289 arg2Of or,using
R1779 T2294 T2293 arg2Of strategies,or
R1780 T2294 T2295 modOf strategies,to
R1781 T2296 T2295 arg1Of block,to
R1782 T2298 T2296 arg2Of signalling,block
R1783 T2298 T2297 arg1Of signalling,TLR
R1784 T2300 T2285 arg1Of identify,Moreover
R1785 T2300 T2286 arg1Of identify,","
R1786 T2300 T2299 arg1Of identify,clearly
R1787 T2300 T2303 arg1Of identify,as
R1788 T2302 T2300 arg2Of inflammation,identify
R1789 T2302 T2301 arg1Of inflammation,TLR-dependent
R1790 T2304 T2303 arg2Of being,as
R1791 T2304 T2306 arg1Of being,in
R1792 T2305 T2304 arg2Of important,being
R1793 T2308 T2306 arg2Of pathogenesis,in
R1794 T2308 T2307 arg1Of pathogenesis,the
R1795 T2308 T2309 arg1Of pathogenesis,of
R1796 T2311 T2309 arg2Of disease,of
R1797 T2311 T2310 arg1Of disease,the

UBERON-AE

Id Subject Object Predicate Lexical cue
T1750 447-454 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues
T1749 279-286 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues

GO-BP

Id Subject Object Predicate Lexical cue
T2512 697-709 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T2505 616-626 http://purl.obolibrary.org/obo/GO_0023052 denotes signalling
T2494 658-670 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T2493 377-389 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T2492 142-154 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation

GO-MF

Id Subject Object Predicate Lexical cue
T2522 478-485 http://purl.obolibrary.org/obo/GO_0005488 denotes ligands
T2521 231-238 http://purl.obolibrary.org/obo/GO_0005488 denotes ligands
T2520 187-194 http://purl.obolibrary.org/obo/GO_0005488 denotes ligands

GO-CC

Id Subject Object Predicate Lexical cue
T2541 274-278 http://purl.obolibrary.org/obo/GO_0018995 denotes host
T2533 291-296 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

sentences

Id Subject Object Predicate Lexical cue
T1767 541-725 Sentence denotes Moreover, animal models using TLR knockout mice or strategies to block TLR signalling clearly identify TLR-dependent inflammation as being important in the pathogenesis of the disease.
T1766 413-540 Sentence denotes TLRs are expressed in RA synovial tissues and various endogenous ligands are present within the inflamed joints of RA patients.
T1765 162-412 Sentence denotes In addition to microbial ligands, an increasing number of endogenous ligands - a group of proteins derived from host tissues and cells - have been reported as candidate activators of TLRs inducing so-called sterile inflammation (reviewed in [14,15]).
T1764 0-161 Sentence denotes Toll-like receptors (TLRs) have been implicated in a variety of autoimmune diseases and are potential candidates for inducing NF-κB-dependent inflammation in RA.
T29 0-161 Sentence denotes Toll-like receptors (TLRs) have been implicated in a variety of autoimmune diseases and are potential candidates for inducing NF-κB-dependent inflammation in RA.
T30 162-412 Sentence denotes In addition to microbial ligands, an increasing number of endogenous ligands - a group of proteins derived from host tissues and cells - have been reported as candidate activators of TLRs inducing so-called sterile inflammation (reviewed in [14,15]).
T31 413-540 Sentence denotes TLRs are expressed in RA synovial tissues and various endogenous ligands are present within the inflamed joints of RA patients.
T32 541-725 Sentence denotes Moreover, animal models using TLR knockout mice or strategies to block TLR signalling clearly identify TLR-dependent inflammation as being important in the pathogenesis of the disease.

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T3696 252-278 Gene_expression denotes proteins derived from host
T3692 0-83 Gene_expression denotes Toll-like receptors (TLRs) have been implicated in a variety of autoimmune diseases
T3691 459-485 Entity denotes various endogenous ligands
T3688 435-437 Protein denotes RA
T3652 584-588 Protein denotes mice
T3648 321-341 Entity denotes candidate activators
T3647 528-530 Protein denotes RA
T3646 252-278 Protein denotes proteins derived from host
T3629 177-195 Entity denotes microbial ligands,
T3622 158-160 Protein denotes RA
T3619 345-389 Protein denotes TLRs inducing so-called sterile inflammation
T3598 0-26 Protein denotes Toll-like receptors (TLRs)
T3594 126-141 Protein denotes NF-κB-dependent
T3593 217-278 Entity denotes of endogenous ligands - a group of proteins derived from host
R2750 T3598 T3692 themeOf Toll-like receptors (TLRs),Toll-like receptors (TLRs) have been implicated in a variety of autoimmune diseases
R2773 T3646 T3696 themeOf proteins derived from host,proteins derived from host

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T3451 606-611 Negative_regulation denotes block
T3450 612-615 Protein denotes TLR
T3449 126-131 Protein denotes NF-κB
R2708 T3450 T3451 themeOf TLR,block