PMC:3148254 / 1184-1367
Annnotations
{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/3148254","sourcedb":"PMC","sourceid":"3148254","source_url":"http://www.ncbi.nlm.nih.gov/pmc/3148254","text":"40 signaling, we used somatic cell gene targeting to generate mouse B cell lines deficient in HOIP. We found that the CD40-induced upregulation of CD80 and activation of germline immu","tracks":[{"project":"bionlp-st-ge-2016-reference","denotations":[{"id":"T104","span":{"begin":81,"end":90},"obj":"Negative_regulation"},{"id":"T105","span":{"begin":94,"end":98},"obj":"Protein"},{"id":"T106","span":{"begin":118,"end":122},"obj":"Protein"},{"id":"T107","span":{"begin":123,"end":130},"obj":"Positive_regulation"},{"id":"T108","span":{"begin":131,"end":143},"obj":"Positive_regulation"},{"id":"T109","span":{"begin":147,"end":151},"obj":"Protein"}],"relations":[{"id":"R48","pred":"themeOf","subj":"T105","obj":"T104"},{"id":"R49","pred":"causeOf","subj":"T106","obj":"T107"},{"id":"R51","pred":"themeOf","subj":"T108","obj":"T107"},{"id":"R52","pred":"themeOf","subj":"T109","obj":"T108"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"attributes":[{"subj":"T104","pred":"source","obj":"bionlp-st-ge-2016-reference"},{"subj":"T105","pred":"source","obj":"bionlp-st-ge-2016-reference"},{"subj":"T106","pred":"source","obj":"bionlp-st-ge-2016-reference"},{"subj":"T107","pred":"source","obj":"bionlp-st-ge-2016-reference"},{"subj":"T108","pred":"source","obj":"bionlp-st-ge-2016-reference"},{"subj":"T109","pred":"source","obj":"bionlp-st-ge-2016-reference"}]},{"project":"bionlp-st-ge-2016-reference-tees","denotations":[{"id":"T921","span":{"begin":118,"end":122},"obj":"Protein"},{"id":"T922","span":{"begin":147,"end":151},"obj":"Protein"},{"id":"T925","span":{"begin":156,"end":166},"obj":"Positive_regulation"}],"attributes":[{"subj":"T921","pred":"source","obj":"bionlp-st-ge-2016-reference-tees"},{"subj":"T922","pred":"source","obj":"bionlp-st-ge-2016-reference-tees"},{"subj":"T925","pred":"source","obj":"bionlp-st-ge-2016-reference-tees"}]},{"project":"events-check-again","denotations":[{"id":"T964","span":{"begin":81,"end":90},"obj":"Negative_regulation"},{"id":"T965","span":{"begin":94,"end":98},"obj":"Protein"},{"id":"T966","span":{"begin":118,"end":122},"obj":"Protein"},{"id":"T967","span":{"begin":123,"end":130},"obj":"Positive_regulation"},{"id":"T968","span":{"begin":131,"end":143},"obj":"Positive_regulation"},{"id":"T969","span":{"begin":147,"end":151},"obj":"Protein"}],"relations":[{"id":"R690","pred":"themeOf","subj":"T965","obj":"T964"},{"id":"R691","pred":"causeOf","subj":"T966","obj":"T967"},{"id":"R693","pred":"themeOf","subj":"T968","obj":"T967"},{"id":"R694","pred":"themeOf","subj":"T969","obj":"T968"}],"attributes":[{"subj":"T964","pred":"source","obj":"events-check-again"},{"subj":"T965","pred":"source","obj":"events-check-again"},{"subj":"T966","pred":"source","obj":"events-check-again"},{"subj":"T967","pred":"source","obj":"events-check-again"},{"subj":"T968","pred":"source","obj":"events-check-again"},{"subj":"T969","pred":"source","obj":"events-check-again"}]},{"project":"pmc-enju-pas","denotations":[{"id":"T603","span":{"begin":3,"end":12},"obj":"NN"},{"id":"T604","span":{"begin":12,"end":13},"obj":"-COMMA-"},{"id":"T605","span":{"begin":14,"end":16},"obj":"PRP"},{"id":"T606","span":{"begin":17,"end":21},"obj":"VB"},{"id":"T607","span":{"begin":22,"end":29},"obj":"JJ"},{"id":"T608","span":{"begin":30,"end":34},"obj":"NN"},{"id":"T609","span":{"begin":35,"end":39},"obj":"NN"},{"id":"T610","span":{"begin":40,"end":49},"obj":"VB"},{"id":"T611","span":{"begin":50,"end":52},"obj":"TO"},{"id":"T612","span":{"begin":53,"end":61},"obj":"VB"},{"id":"T613","span":{"begin":62,"end":67},"obj":"NN"},{"id":"T614","span":{"begin":68,"end":69},"obj":"NN"},{"id":"T615","span":{"begin":70,"end":74},"obj":"NN"},{"id":"T616","span":{"begin":75,"end":80},"obj":"NN"},{"id":"T617","span":{"begin":81,"end":90},"obj":"JJ"},{"id":"T618","span":{"begin":91,"end":93},"obj":"IN"},{"id":"T619","span":{"begin":94,"end":98},"obj":"NN"},{"id":"T620","span":{"begin":100,"end":102},"obj":"PRP"},{"id":"T621","span":{"begin":103,"end":108},"obj":"VB"},{"id":"T622","span":{"begin":109,"end":113},"obj":"IN"},{"id":"T623","span":{"begin":114,"end":117},"obj":"DT"},{"id":"T624","span":{"begin":118,"end":130},"obj":"JJ"},{"id":"T625","span":{"begin":131,"end":143},"obj":"NN"},{"id":"T626","span":{"begin":144,"end":146},"obj":"IN"},{"id":"T627","span":{"begin":147,"end":151},"obj":"NN"},{"id":"T628","span":{"begin":152,"end":155},"obj":"CC"},{"id":"T629","span":{"begin":156,"end":166},"obj":"NN"},{"id":"T630","span":{"begin":167,"end":169},"obj":"IN"},{"id":"T631","span":{"begin":170,"end":178},"obj":"NN"}],"relations":[{"id":"R521","pred":"arg1Of","subj":"T605","obj":"T606"},{"id":"R523","pred":"arg1Of","subj":"T606","obj":"T604"},{"id":"R524","pred":"modOf","subj":"T606","obj":"T611"},{"id":"R525","pred":"arg2Of","subj":"T609","obj":"T606"},{"id":"R526","pred":"arg1Of","subj":"T609","obj":"T607"},{"id":"R527","pred":"arg1Of","subj":"T609","obj":"T608"},{"id":"R528","pred":"arg3Of","subj":"T610","obj":"T606"},{"id":"R529","pred":"arg1Of","subj":"T612","obj":"T611"},{"id":"R530","pred":"arg2Of","subj":"T616","obj":"T612"},{"id":"R531","pred":"arg1Of","subj":"T616","obj":"T613"},{"id":"R532","pred":"arg1Of","subj":"T616","obj":"T614"},{"id":"R533","pred":"arg1Of","subj":"T616","obj":"T615"},{"id":"R534","pred":"arg1Of","subj":"T616","obj":"T617"},{"id":"R535","pred":"arg1Of","subj":"T617","obj":"T618"},{"id":"R536","pred":"arg2Of","subj":"T619","obj":"T618"},{"id":"R537","pred":"arg1Of","subj":"T620","obj":"T621"},{"id":"R538","pred":"arg1Of","subj":"T625","obj":"T623"},{"id":"R539","pred":"arg1Of","subj":"T625","obj":"T624"},{"id":"R540","pred":"arg1Of","subj":"T625","obj":"T626"},{"id":"R541","pred":"arg1Of","subj":"T625","obj":"T628"},{"id":"R542","pred":"arg2Of","subj":"T627","obj":"T626"},{"id":"R545","pred":"arg2Of","subj":"T629","obj":"T628"},{"id":"R546","pred":"arg1Of","subj":"T629","obj":"T630"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"attributes":[{"subj":"T603","pred":"source","obj":"pmc-enju-pas"},{"subj":"T604","pred":"source","obj":"pmc-enju-pas"},{"subj":"T605","pred":"source","obj":"pmc-enju-pas"},{"subj":"T606","pred":"source","obj":"pmc-enju-pas"},{"subj":"T607","pred":"source","obj":"pmc-enju-pas"},{"subj":"T608","pred":"source","obj":"pmc-enju-pas"},{"subj":"T609","pred":"source","obj":"pmc-enju-pas"},{"subj":"T610","pred":"source","obj":"pmc-enju-pas"},{"subj":"T611","pred":"source","obj":"pmc-enju-pas"},{"subj":"T612","pred":"source","obj":"pmc-enju-pas"},{"subj":"T613","pred":"source","obj":"pmc-enju-pas"},{"subj":"T614","pred":"source","obj":"pmc-enju-pas"},{"subj":"T615","pred":"source","obj":"pmc-enju-pas"},{"subj":"T616","pred":"source","obj":"pmc-enju-pas"},{"subj":"T617","pred":"source","obj":"pmc-enju-pas"},{"subj":"T618","pred":"source","obj":"pmc-enju-pas"},{"subj":"T619","pred":"source","obj":"pmc-enju-pas"},{"subj":"T620","pred":"source","obj":"pmc-enju-pas"},{"subj":"T621","pred":"source","obj":"pmc-enju-pas"},{"subj":"T622","pred":"source","obj":"pmc-enju-pas"},{"subj":"T623","pred":"source","obj":"pmc-enju-pas"},{"subj":"T624","pred":"source","obj":"pmc-enju-pas"},{"subj":"T625","pred":"source","obj":"pmc-enju-pas"},{"subj":"T626","pred":"source","obj":"pmc-enju-pas"},{"subj":"T627","pred":"source","obj":"pmc-enju-pas"},{"subj":"T628","pred":"source","obj":"pmc-enju-pas"},{"subj":"T629","pred":"source","obj":"pmc-enju-pas"},{"subj":"T630","pred":"source","obj":"pmc-enju-pas"},{"subj":"T631","pred":"source","obj":"pmc-enju-pas"}]},{"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T320","span":{"begin":3,"end":12},"obj":"VBG"},{"id":"T321","span":{"begin":12,"end":13},"obj":","},{"id":"T322","span":{"begin":14,"end":16},"obj":"PRP"},{"id":"T323","span":{"begin":17,"end":21},"obj":"VBD"},{"id":"T324","span":{"begin":22,"end":29},"obj":"JJ"},{"id":"T325","span":{"begin":30,"end":34},"obj":"NN"},{"id":"T326","span":{"begin":35,"end":39},"obj":"NN"},{"id":"T327","span":{"begin":40,"end":49},"obj":"VBG"},{"id":"T328","span":{"begin":50,"end":52},"obj":"TO"},{"id":"T329","span":{"begin":53,"end":61},"obj":"VB"},{"id":"T330","span":{"begin":62,"end":67},"obj":"NN"},{"id":"T331","span":{"begin":68,"end":69},"obj":"NNP"},{"id":"T332","span":{"begin":70,"end":74},"obj":"NN"},{"id":"T333","span":{"begin":75,"end":80},"obj":"NNS"},{"id":"T334","span":{"begin":81,"end":90},"obj":"VBP"},{"id":"T335","span":{"begin":91,"end":93},"obj":"IN"},{"id":"T336","span":{"begin":94,"end":98},"obj":"NNP"},{"id":"T337","span":{"begin":98,"end":99},"obj":"."},{"id":"T338","span":{"begin":100,"end":102},"obj":"PRP"},{"id":"T339","span":{"begin":103,"end":108},"obj":"VBD"},{"id":"T340","span":{"begin":109,"end":113},"obj":"IN"},{"id":"T341","span":{"begin":114,"end":117},"obj":"DT"},{"id":"T342","span":{"begin":118,"end":130},"obj":"JJ"},{"id":"T343","span":{"begin":131,"end":143},"obj":"NN"},{"id":"T344","span":{"begin":144,"end":146},"obj":"IN"},{"id":"T345","span":{"begin":147,"end":151},"obj":"NNP"},{"id":"T346","span":{"begin":152,"end":155},"obj":"CC"},{"id":"T347","span":{"begin":156,"end":166},"obj":"NN"},{"id":"T348","span":{"begin":167,"end":169},"obj":"IN"},{"id":"T349","span":{"begin":170,"end":178},"obj":"NN"}],"relations":[{"id":"R243","pred":"punct","subj":"T321","obj":"T323"},{"id":"R244","pred":"nsubj","subj":"T322","obj":"T323"},{"id":"R245","pred":"ROOT","subj":"T323","obj":"T323"},{"id":"R246","pred":"compound","subj":"T324","obj":"T326"},{"id":"R247","pred":"compound","subj":"T325","obj":"T326"},{"id":"R248","pred":"dobj","subj":"T326","obj":"T323"},{"id":"R249","pred":"acl","subj":"T327","obj":"T326"},{"id":"R250","pred":"aux","subj":"T328","obj":"T329"},{"id":"R251","pred":"xcomp","subj":"T329","obj":"T327"},{"id":"R252","pred":"compound","subj":"T330","obj":"T333"},{"id":"R253","pred":"compound","subj":"T331","obj":"T332"},{"id":"R254","pred":"compound","subj":"T332","obj":"T333"},{"id":"R255","pred":"dobj","subj":"T333","obj":"T329"},{"id":"R256","pred":"oprd","subj":"T334","obj":"T323"},{"id":"R257","pred":"prep","subj":"T335","obj":"T334"},{"id":"R258","pred":"pobj","subj":"T336","obj":"T335"},{"id":"R259","pred":"punct","subj":"T337","obj":"T323"},{"id":"R260","pred":"nsubj","subj":"T338","obj":"T339"},{"id":"R261","pred":"ROOT","subj":"T339","obj":"T339"},{"id":"R263","pred":"det","subj":"T341","obj":"T343"},{"id":"R264","pred":"amod","subj":"T342","obj":"T343"},{"id":"R266","pred":"prep","subj":"T344","obj":"T343"},{"id":"R267","pred":"pobj","subj":"T345","obj":"T344"},{"id":"R268","pred":"cc","subj":"T346","obj":"T345"},{"id":"R269","pred":"conj","subj":"T347","obj":"T343"},{"id":"R270","pred":"prep","subj":"T348","obj":"T347"}],"attributes":[{"subj":"T320","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T321","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T322","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T323","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T324","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T325","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T326","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T327","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T328","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T329","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T330","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T331","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T332","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T333","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T334","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T335","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T336","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T337","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T338","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T339","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T340","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T341","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T342","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T343","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T344","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T345","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T346","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T347","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T348","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T349","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"}]},{"project":"GO-BP","denotations":[{"id":"T762","span":{"begin":3,"end":12},"obj":"http://purl.obolibrary.org/obo/GO_0023052"}],"attributes":[{"subj":"T762","pred":"source","obj":"GO-BP"}]},{"project":"GO-CC","denotations":[{"id":"T802","span":{"begin":30,"end":34},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T803","span":{"begin":70,"end":74},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"attributes":[{"subj":"T802","pred":"source","obj":"GO-CC"},{"subj":"T803","pred":"source","obj":"GO-CC"}]},{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T726","span":{"begin":94,"end":98},"obj":"Q96EP0"},{"id":"T727","span":{"begin":118,"end":122},"obj":"P25942"},{"id":"T728","span":{"begin":147,"end":151},"obj":"P33681"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"attributes":[{"subj":"T726","pred":"source","obj":"bionlp-st-ge-2016-uniprot"},{"subj":"T727","pred":"source","obj":"bionlp-st-ge-2016-uniprot"},{"subj":"T728","pred":"source","obj":"bionlp-st-ge-2016-uniprot"}]},{"project":"test2","denotations":[{"id":"T64","span":{"begin":81,"end":90},"obj":"Negative_regulation"},{"id":"T65","span":{"begin":94,"end":98},"obj":"Protein"},{"id":"T66","span":{"begin":118,"end":122},"obj":"Protein"},{"id":"T67","span":{"begin":123,"end":130},"obj":"Positive_regulation"},{"id":"T68","span":{"begin":131,"end":143},"obj":"Positive_regulation"},{"id":"T69","span":{"begin":147,"end":151},"obj":"Protein"},{"id":"T70","span":{"begin":156,"end":166},"obj":"Positive_regulation"}],"relations":[{"id":"R30","pred":"themeOf","subj":"T65","obj":"T64"},{"id":"R31","pred":"causeOf","subj":"T66","obj":"T67"},{"id":"R32","pred":"themeOf","subj":"T68","obj":"T67"},{"id":"R33","pred":"themeOf","subj":"T69","obj":"T68"}],"attributes":[{"subj":"T64","pred":"source","obj":"test2"},{"subj":"T65","pred":"source","obj":"test2"},{"subj":"T66","pred":"source","obj":"test2"},{"subj":"T67","pred":"source","obj":"test2"},{"subj":"T68","pred":"source","obj":"test2"},{"subj":"T69","pred":"source","obj":"test2"},{"subj":"T70","pred":"source","obj":"test2"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"bionlp-st-ge-2016-reference","color":"#a6ec93","default":true},{"id":"bionlp-st-ge-2016-reference-tees","color":"#ec93c0"},{"id":"events-check-again","color":"#93daec"},{"id":"pmc-enju-pas","color":"#ece493"},{"id":"bionlp-st-ge-2016-spacy-parsed","color":"#ca93ec"},{"id":"GO-BP","color":"#93ecb0"},{"id":"GO-CC","color":"#ec9693"},{"id":"bionlp-st-ge-2016-uniprot","color":"#93a9ec"},{"id":"test2","color":"#c3ec93"}]}]}}