PMC:3148254 / 1184-1367 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T104	81-90	Negative_regulation	denotes	deficient
T105	94-98	Protein	denotes	HOIP
T106	118-122	Protein	denotes	CD40
T107	123-130	Positive_regulation	denotes	induced
T108	131-143	Positive_regulation	denotes	upregulation
T109	147-151	Protein	denotes	CD80
R48	T105	T104	themeOf	HOIP,deficient
R49	T106	T107	causeOf	CD40,induced
R51	T108	T107	themeOf	upregulation,induced
R52	T109	T108	themeOf	CD80,upregulation

Id	Subject	Object	Predicate	Lexical cue
T921	118-122	Protein	denotes	CD40
T922	147-151	Protein	denotes	CD80
T925	156-166	Positive_regulation	denotes	activation

Id	Subject	Object	Predicate	Lexical cue
T964	81-90	Negative_regulation	denotes	deficient
T965	94-98	Protein	denotes	HOIP
T966	118-122	Protein	denotes	CD40
T967	123-130	Positive_regulation	denotes	induced
T968	131-143	Positive_regulation	denotes	upregulation
T969	147-151	Protein	denotes	CD80
R690	T965	T964	themeOf	HOIP,deficient
R691	T966	T967	causeOf	CD40,induced
R693	T968	T967	themeOf	upregulation,induced
R694	T969	T968	themeOf	CD80,upregulation

Id	Subject	Object	Predicate	Lexical cue
T603	3-12	NN	denotes	signaling
T604	12-13	-COMMA-	denotes	,
T605	14-16	PRP	denotes	we
T606	17-21	VB	denotes	used
T607	22-29	JJ	denotes	somatic
T608	30-34	NN	denotes	cell
T609	35-39	NN	denotes	gene
T610	40-49	VB	denotes	targeting
T611	50-52	TO	denotes	to
T612	53-61	VB	denotes	generate
T613	62-67	NN	denotes	mouse
T614	68-69	NN	denotes	B
T615	70-74	NN	denotes	cell
T616	75-80	NN	denotes	lines
T617	81-90	JJ	denotes	deficient
T618	91-93	IN	denotes	in
T619	94-98	NN	denotes	HOIP
T620	100-102	PRP	denotes	We
T621	103-108	VB	denotes	found
T622	109-113	IN	denotes	that
T623	114-117	DT	denotes	the
T624	118-130	JJ	denotes	CD40-induced
T625	131-143	NN	denotes	upregulation
T626	144-146	IN	denotes	of
T627	147-151	NN	denotes	CD80
T628	152-155	CC	denotes	and
T629	156-166	NN	denotes	activation
T630	167-169	IN	denotes	of
T631	170-178	NN	denotes	germline
R521	T605	T606	arg1Of	we,used
R523	T606	T604	arg1Of	used,","
R524	T606	T611	modOf	used,to
R525	T609	T606	arg2Of	gene,used
R526	T609	T607	arg1Of	gene,somatic
R527	T609	T608	arg1Of	gene,cell
R528	T610	T606	arg3Of	targeting,used
R529	T612	T611	arg1Of	generate,to
R530	T616	T612	arg2Of	lines,generate
R531	T616	T613	arg1Of	lines,mouse
R532	T616	T614	arg1Of	lines,B
R533	T616	T615	arg1Of	lines,cell
R534	T616	T617	arg1Of	lines,deficient
R535	T617	T618	arg1Of	deficient,in
R536	T619	T618	arg2Of	HOIP,in
R537	T620	T621	arg1Of	We,found
R538	T625	T623	arg1Of	upregulation,the
R539	T625	T624	arg1Of	upregulation,CD40-induced
R540	T625	T626	arg1Of	upregulation,of
R541	T625	T628	arg1Of	upregulation,and
R542	T627	T626	arg2Of	CD80,of
R545	T629	T628	arg2Of	activation,and
R546	T629	T630	arg1Of	activation,of

Id	Subject	Object	Predicate	Lexical cue
T320	3-12	VBG	denotes	signaling
T321	12-13	,	denotes	,
T322	14-16	PRP	denotes	we
T323	17-21	VBD	denotes	used
T324	22-29	JJ	denotes	somatic
T325	30-34	NN	denotes	cell
T326	35-39	NN	denotes	gene
T327	40-49	VBG	denotes	targeting
T328	50-52	TO	denotes	to
T329	53-61	VB	denotes	generate
T330	62-67	NN	denotes	mouse
T331	68-69	NNP	denotes	B
T332	70-74	NN	denotes	cell
T333	75-80	NNS	denotes	lines
T334	81-90	VBP	denotes	deficient
T335	91-93	IN	denotes	in
T336	94-98	NNP	denotes	HOIP
T337	98-99	.	denotes	.
T338	100-102	PRP	denotes	We
T339	103-108	VBD	denotes	found
T340	109-113	IN	denotes	that
T341	114-117	DT	denotes	the
T342	118-130	JJ	denotes	CD40-induced
T343	131-143	NN	denotes	upregulation
T344	144-146	IN	denotes	of
T345	147-151	NNP	denotes	CD80
T346	152-155	CC	denotes	and
T347	156-166	NN	denotes	activation
T348	167-169	IN	denotes	of
T349	170-178	NN	denotes	germline
R243	T321	T323	punct	",",used
R244	T322	T323	nsubj	we,used
R245	T323	T323	ROOT	used,used
R246	T324	T326	compound	somatic,gene
R247	T325	T326	compound	cell,gene
R248	T326	T323	dobj	gene,used
R249	T327	T326	acl	targeting,gene
R250	T328	T329	aux	to,generate
R251	T329	T327	xcomp	generate,targeting
R252	T330	T333	compound	mouse,lines
R253	T331	T332	compound	B,cell
R254	T332	T333	compound	cell,lines
R255	T333	T329	dobj	lines,generate
R256	T334	T323	oprd	deficient,used
R257	T335	T334	prep	in,deficient
R258	T336	T335	pobj	HOIP,in
R259	T337	T323	punct	.,used
R260	T338	T339	nsubj	We,found
R261	T339	T339	ROOT	found,found
R263	T341	T343	det	the,upregulation
R264	T342	T343	amod	CD40-induced,upregulation
R266	T344	T343	prep	of,upregulation
R267	T345	T344	pobj	CD80,of
R268	T346	T345	cc	and,CD80
R269	T347	T343	conj	activation,upregulation
R270	T348	T347	prep	of,activation

Id	Subject	Object	Predicate	Lexical cue
T762	3-12	http://purl.obolibrary.org/obo/GO_0023052	denotes	signaling

Id	Subject	Object	Predicate	Lexical cue
T802	30-34	http://purl.obolibrary.org/obo/GO_0005623	denotes	cell
T803	70-74	http://purl.obolibrary.org/obo/GO_0005623	denotes	cell

Id	Subject	Object	Predicate	Lexical cue
T726	94-98	Q96EP0	denotes	HOIP
T727	118-122	P25942	denotes	CD40
T728	147-151	P33681	denotes	CD80

Id	Subject	Object	Predicate	Lexical cue
T64	81-90	Negative_regulation	denotes	deficient
T65	94-98	Protein	denotes	HOIP
T66	118-122	Protein	denotes	CD40
T67	123-130	Positive_regulation	denotes	induced
T68	131-143	Positive_regulation	denotes	upregulation
T69	147-151	Protein	denotes	CD80
T70	156-166	Positive_regulation	denotes	activation
R30	T65	T64	themeOf	HOIP,deficient
R31	T66	T67	causeOf	CD40,induced
R32	T68	T67	themeOf	upregulation,induced
R33	T69	T68	themeOf	CD80,upregulation