PMC:2948165 / 21098-23138 JSONTXT

{"project":"TEST0","denotations":[{"id":"20585784-65-71-46874","span":{"begin":91,"end":93},"obj":"[\"1896824\"]"},{"id":"20585784-122-127-46875","span":{"begin":595,"end":596},"obj":"[\"9862835\"]"},{"id":"20585784-207-213-46876","span":{"begin":680,"end":682},"obj":"[\"16706813\"]"},{"id":"20585784-231-237-46877","span":{"begin":1822,"end":1824},"obj":"[\"12147861\"]"},{"id":"20585784-235-241-46878","span":{"begin":1826,"end":1828},"obj":"[\"12704042\"]"}],"text":"Discussion and conclusion\nThe prevalence of functional gastrointestinal disorders is high [12], but no single diagnostic test has been generally recommended for clinical use in patients with suspected functional dyspepsia. All available tests have certain disadvantages that prevent them from being used in the clinical environment. The barostat, for example, is an invasive test that comprises the use of an intragastric balloon and therefore has poor patient acceptance. Nuclear studies are associated with considerable exposure to ionizing radiation and lack spatial and temporal resolution [8], as does electro-gastrography, which gives no details about gastric contractions [24].\nTherefore, since the early 1990s, researchers have searched for a non-invasive, non-radiation technique that has sufficient diagnostic accuracy, as well as patient acceptance. As MRI is becoming more and more widely available, involves no exposure to ionizing radiation and is accepted by patients in the clinical setting since it does not require any oral intubation, MRI has been proposed for evaluation of gastric functional disorders.\nFirst attempts were hampered by long aquisition times that resulted in poor image quality and less robust results. But as experience with MRI has increased and aquisition times have become shorter, MRI has proved to be a promising new technique for evaluation of gastric function. Standard fast MRI techniques allow complete depiction of the stomach volume and gastric peristalsis in sufficient temporal and spatial resolution without exposure to ionizing radiation.\nMRI has evolved from a technique that evaluates gastric function in healthy subjects to a technique that evaluates the effect of pharmaceutical products in patients with functional dyspepsia or other disorders of gastric function [15, 17].\nIn smaller research and clinical settings, MRI has been shown to be able to evaluate both gastric emptying and gastric motility. Now the technique should be evaluated in the clinical setting on a larger scale."}

{"project":"0_colil","denotations":[{"id":"20585784-1896824-46874","span":{"begin":91,"end":93},"obj":"1896824"},{"id":"20585784-9862835-46875","span":{"begin":595,"end":596},"obj":"9862835"},{"id":"20585784-16706813-46876","span":{"begin":680,"end":682},"obj":"16706813"},{"id":"20585784-12147861-46877","span":{"begin":1822,"end":1824},"obj":"12147861"},{"id":"20585784-12704042-46878","span":{"begin":1826,"end":1828},"obj":"12704042"}],"text":"Discussion and conclusion\nThe prevalence of functional gastrointestinal disorders is high [12], but no single diagnostic test has been generally recommended for clinical use in patients with suspected functional dyspepsia. All available tests have certain disadvantages that prevent them from being used in the clinical environment. The barostat, for example, is an invasive test that comprises the use of an intragastric balloon and therefore has poor patient acceptance. Nuclear studies are associated with considerable exposure to ionizing radiation and lack spatial and temporal resolution [8], as does electro-gastrography, which gives no details about gastric contractions [24].\nTherefore, since the early 1990s, researchers have searched for a non-invasive, non-radiation technique that has sufficient diagnostic accuracy, as well as patient acceptance. As MRI is becoming more and more widely available, involves no exposure to ionizing radiation and is accepted by patients in the clinical setting since it does not require any oral intubation, MRI has been proposed for evaluation of gastric functional disorders.\nFirst attempts were hampered by long aquisition times that resulted in poor image quality and less robust results. But as experience with MRI has increased and aquisition times have become shorter, MRI has proved to be a promising new technique for evaluation of gastric function. Standard fast MRI techniques allow complete depiction of the stomach volume and gastric peristalsis in sufficient temporal and spatial resolution without exposure to ionizing radiation.\nMRI has evolved from a technique that evaluates gastric function in healthy subjects to a technique that evaluates the effect of pharmaceutical products in patients with functional dyspepsia or other disorders of gastric function [15, 17].\nIn smaller research and clinical settings, MRI has been shown to be able to evaluate both gastric emptying and gastric motility. Now the technique should be evaluated in the clinical setting on a larger scale."}

{"project":"2_test","denotations":[{"id":"20585784-1896824-29356010","span":{"begin":91,"end":93},"obj":"1896824"},{"id":"20585784-9862835-29356011","span":{"begin":595,"end":596},"obj":"9862835"},{"id":"20585784-16706813-29356012","span":{"begin":680,"end":682},"obj":"16706813"},{"id":"20585784-12147861-29356013","span":{"begin":1822,"end":1824},"obj":"12147861"},{"id":"20585784-12704042-29356014","span":{"begin":1826,"end":1828},"obj":"12704042"}],"text":"Discussion and conclusion\nThe prevalence of functional gastrointestinal disorders is high [12], but no single diagnostic test has been generally recommended for clinical use in patients with suspected functional dyspepsia. All available tests have certain disadvantages that prevent them from being used in the clinical environment. The barostat, for example, is an invasive test that comprises the use of an intragastric balloon and therefore has poor patient acceptance. Nuclear studies are associated with considerable exposure to ionizing radiation and lack spatial and temporal resolution [8], as does electro-gastrography, which gives no details about gastric contractions [24].\nTherefore, since the early 1990s, researchers have searched for a non-invasive, non-radiation technique that has sufficient diagnostic accuracy, as well as patient acceptance. As MRI is becoming more and more widely available, involves no exposure to ionizing radiation and is accepted by patients in the clinical setting since it does not require any oral intubation, MRI has been proposed for evaluation of gastric functional disorders.\nFirst attempts were hampered by long aquisition times that resulted in poor image quality and less robust results. But as experience with MRI has increased and aquisition times have become shorter, MRI has proved to be a promising new technique for evaluation of gastric function. Standard fast MRI techniques allow complete depiction of the stomach volume and gastric peristalsis in sufficient temporal and spatial resolution without exposure to ionizing radiation.\nMRI has evolved from a technique that evaluates gastric function in healthy subjects to a technique that evaluates the effect of pharmaceutical products in patients with functional dyspepsia or other disorders of gastric function [15, 17].\nIn smaller research and clinical settings, MRI has been shown to be able to evaluate both gastric emptying and gastric motility. Now the technique should be evaluated in the clinical setting on a larger scale."}

{"project":"MyTest","denotations":[{"id":"20585784-1896824-29356010","span":{"begin":91,"end":93},"obj":"1896824"},{"id":"20585784-9862835-29356011","span":{"begin":595,"end":596},"obj":"9862835"},{"id":"20585784-16706813-29356012","span":{"begin":680,"end":682},"obj":"16706813"},{"id":"20585784-12147861-29356013","span":{"begin":1822,"end":1824},"obj":"12147861"},{"id":"20585784-12704042-29356014","span":{"begin":1826,"end":1828},"obj":"12704042"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"Discussion and conclusion\nThe prevalence of functional gastrointestinal disorders is high [12], but no single diagnostic test has been generally recommended for clinical use in patients with suspected functional dyspepsia. All available tests have certain disadvantages that prevent them from being used in the clinical environment. The barostat, for example, is an invasive test that comprises the use of an intragastric balloon and therefore has poor patient acceptance. Nuclear studies are associated with considerable exposure to ionizing radiation and lack spatial and temporal resolution [8], as does electro-gastrography, which gives no details about gastric contractions [24].\nTherefore, since the early 1990s, researchers have searched for a non-invasive, non-radiation technique that has sufficient diagnostic accuracy, as well as patient acceptance. As MRI is becoming more and more widely available, involves no exposure to ionizing radiation and is accepted by patients in the clinical setting since it does not require any oral intubation, MRI has been proposed for evaluation of gastric functional disorders.\nFirst attempts were hampered by long aquisition times that resulted in poor image quality and less robust results. But as experience with MRI has increased and aquisition times have become shorter, MRI has proved to be a promising new technique for evaluation of gastric function. Standard fast MRI techniques allow complete depiction of the stomach volume and gastric peristalsis in sufficient temporal and spatial resolution without exposure to ionizing radiation.\nMRI has evolved from a technique that evaluates gastric function in healthy subjects to a technique that evaluates the effect of pharmaceutical products in patients with functional dyspepsia or other disorders of gastric function [15, 17].\nIn smaller research and clinical settings, MRI has been shown to be able to evaluate both gastric emptying and gastric motility. Now the technique should be evaluated in the clinical setting on a larger scale."}