PMC:2889865 / 11628-12156
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4 Inhibition of NF-κB activity by NAI. Jurkat T-cells were transfected with luciferase reporter plasmids containing either NF-κB or AP-1 cis-acting elements. The cells were incubated with NF-κB activation inhibitor (NAI) for 1 h followed by stimulation with PMA (162 nM, A and C) or HK E. coli (5 × 107 CFU/ml, B and D) for 24 h. (A, B) NF-κB, but not (C, D) AP-1 was inhibited. Statistical significance from the positive control (PMA/HK E. coli) was determined using Student's t-test. (n = 4). Controls were set to 1.\nF"}
GO-BP
{"project":"GO-BP","denotations":[{"id":"T16108","span":{"begin":196,"end":212},"obj":"http://purl.obolibrary.org/obo/GO_0051092"},{"id":"T16109","span":{"begin":196,"end":222},"obj":"http://purl.obolibrary.org/obo/GO_1903721"}],"text":"Figure 4 Inhibition of NF-κB activity by NAI. Jurkat T-cells were transfected with luciferase reporter plasmids containing either NF-κB or AP-1 cis-acting elements. The cells were incubated with NF-κB activation inhibitor (NAI) for 1 h followed by stimulation with PMA (162 nM, A and C) or HK E. coli (5 × 107 CFU/ml, B and D) for 24 h. (A, B) NF-κB, but not (C, D) AP-1 was inhibited. Statistical significance from the positive control (PMA/HK E. coli) was determined using Student's t-test. (n = 4). Controls were set to 1.\nF"}
GO-CC
{"project":"GO-CC","denotations":[{"id":"T16110","span":{"begin":56,"end":61},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T16111","span":{"begin":170,"end":175},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"Figure 4 Inhibition of NF-κB activity by NAI. Jurkat T-cells were transfected with luciferase reporter plasmids containing either NF-κB or AP-1 cis-acting elements. The cells were incubated with NF-κB activation inhibitor (NAI) for 1 h followed by stimulation with PMA (162 nM, A and C) or HK E. coli (5 × 107 CFU/ml, B and D) for 24 h. (A, B) NF-κB, but not (C, D) AP-1 was inhibited. Statistical significance from the positive control (PMA/HK E. coli) was determined using Student's t-test. (n = 4). Controls were set to 1.\nF"}
sentences
{"project":"sentences","denotations":[{"id":"T15871","span":{"begin":10,"end":46},"obj":"Sentence"},{"id":"T15872","span":{"begin":47,"end":165},"obj":"Sentence"},{"id":"T15873","span":{"begin":166,"end":386},"obj":"Sentence"},{"id":"T15874","span":{"begin":387,"end":502},"obj":"Sentence"},{"id":"T15875","span":{"begin":503,"end":526},"obj":"Sentence"},{"id":"T87","span":{"begin":0,"end":46},"obj":"Sentence"},{"id":"T88","span":{"begin":47,"end":165},"obj":"Sentence"},{"id":"T89","span":{"begin":166,"end":386},"obj":"Sentence"},{"id":"T90","span":{"begin":387,"end":502},"obj":"Sentence"},{"id":"T91","span":{"begin":503,"end":526},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Figure 4 Inhibition of NF-κB activity by NAI. Jurkat T-cells were transfected with luciferase reporter plasmids containing either NF-κB or AP-1 cis-acting elements. The cells were incubated with NF-κB activation inhibitor (NAI) for 1 h followed by stimulation with PMA (162 nM, A and C) or HK E. coli (5 × 107 CFU/ml, B and D) for 24 h. (A, B) NF-κB, but not (C, D) AP-1 was inhibited. Statistical significance from the positive control (PMA/HK E. coli) was determined using Student's t-test. (n = 4). Controls were set to 1.\nF"}
events-check-again
{"project":"events-check-again","denotations":[{"id":"T16117","span":{"begin":84,"end":94},"obj":"Protein"}],"text":"Figure 4 Inhibition of NF-κB activity by NAI. Jurkat T-cells were transfected with luciferase reporter plasmids containing either NF-κB or AP-1 cis-acting elements. The cells were incubated with NF-κB activation inhibitor (NAI) for 1 h followed by stimulation with PMA (162 nM, A and C) or HK E. coli (5 × 107 CFU/ml, B and D) for 24 h. (A, B) NF-κB, but not (C, D) AP-1 was inhibited. Statistical significance from the positive control (PMA/HK E. coli) was determined using Student's t-test. (n = 4). Controls were set to 1.\nF"}
bionlp-st-ge-2016-reference-tees
{"project":"bionlp-st-ge-2016-reference-tees","denotations":[{"id":"T16118","span":{"begin":24,"end":29},"obj":"Protein"},{"id":"T16119","span":{"begin":10,"end":20},"obj":"Negative_regulation"},{"id":"T16120","span":{"begin":84,"end":94},"obj":"Protein"},{"id":"T16121","span":{"begin":131,"end":136},"obj":"Protein"},{"id":"T16122","span":{"begin":140,"end":144},"obj":"Protein"},{"id":"T16123","span":{"begin":196,"end":201},"obj":"Protein"},{"id":"T16124","span":{"begin":345,"end":350},"obj":"Protein"},{"id":"T16125","span":{"begin":376,"end":385},"obj":"Negative_regulation"}],"relations":[{"id":"R13114","pred":"themeOf","subj":"T16118","obj":"T16119"},{"id":"R13115","pred":"themeOf","subj":"T16124","obj":"T16125"}],"text":"Figure 4 Inhibition of NF-κB activity by NAI. Jurkat T-cells were transfected with luciferase reporter plasmids containing either NF-κB or AP-1 cis-acting elements. The cells were incubated with NF-κB activation inhibitor (NAI) for 1 h followed by stimulation with PMA (162 nM, A and C) or HK E. coli (5 × 107 CFU/ml, B and D) for 24 h. (A, B) NF-κB, but not (C, D) AP-1 was inhibited. Statistical significance from the positive control (PMA/HK E. coli) was determined using Student's t-test. (n = 4). Controls were set to 1.\nF"}
bionlp-st-ge-2016-reference
{"project":"bionlp-st-ge-2016-reference","denotations":[{"id":"T15870","span":{"begin":84,"end":94},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Figure 4 Inhibition of NF-κB activity by NAI. Jurkat T-cells were transfected with luciferase reporter plasmids containing either NF-κB or AP-1 cis-acting elements. The cells were incubated with NF-κB activation inhibitor (NAI) for 1 h followed by stimulation with PMA (162 nM, A and C) or HK E. coli (5 × 107 CFU/ml, B and D) for 24 h. (A, B) NF-κB, but not (C, D) AP-1 was inhibited. Statistical significance from the positive control (PMA/HK E. coli) was determined using Student's t-test. (n = 4). Controls were set to 1.\nF"}
bionlp-st-ge-2016-uniprot
{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T16100","span":{"begin":84,"end":94},"obj":"P08659"},{"id":"T16101","span":{"begin":140,"end":144},"obj":"P05412"},{"id":"T16102","span":{"begin":367,"end":371},"obj":"P05412"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"Figure 4 Inhibition of NF-κB activity by NAI. Jurkat T-cells were transfected with luciferase reporter plasmids containing either NF-κB or AP-1 cis-acting elements. The cells were incubated with NF-κB activation inhibitor (NAI) for 1 h followed by stimulation with PMA (162 nM, A and C) or HK E. coli (5 × 107 CFU/ml, B and D) for 24 h. (A, B) NF-κB, but not (C, D) AP-1 was inhibited. Statistical significance from the positive control (PMA/HK E. coli) was determined using Student's t-test. (n = 4). Controls were set to 1.\nF"}
test2
{"project":"test2","denotations":[{"id":"T15869","span":{"begin":84,"end":94},"obj":"Protein"}],"text":"Figure 4 Inhibition of NF-κB activity by NAI. Jurkat T-cells were transfected with luciferase reporter plasmids containing either NF-κB or AP-1 cis-acting elements. The cells were incubated with NF-κB activation inhibitor (NAI) for 1 h followed by stimulation with PMA (162 nM, A and C) or HK E. coli (5 × 107 CFU/ml, B and D) for 24 h. (A, B) NF-κB, but not (C, D) AP-1 was inhibited. Statistical significance from the positive control (PMA/HK E. coli) was determined using Student's t-test. (n = 4). Controls were set to 1.\nF"}