PMC:2871132 / 263618-265386 JSONTXT

{"project":"NEUROSES","denotations":[{"id":"T5443","span":{"begin":103,"end":111},"obj":"PATO_0002118"},{"id":"T5444","span":{"begin":103,"end":111},"obj":"PATO_0002118"},{"id":"T5445","span":{"begin":516,"end":529},"obj":"PATO_0000021"},{"id":"T5446","span":{"begin":600,"end":613},"obj":"PATO_0000021"},{"id":"T5447","span":{"begin":727,"end":740},"obj":"PATO_0000021"},{"id":"T5448","span":{"begin":970,"end":983},"obj":"PATO_0000021"},{"id":"T5449","span":{"begin":999,"end":1012},"obj":"PATO_0000021"},{"id":"T5450","span":{"begin":549,"end":560},"obj":"PATO_0001772"},{"id":"T5451","span":{"begin":561,"end":565},"obj":"PATO_0000386"},{"id":"T5452","span":{"begin":690,"end":694},"obj":"PATO_0000386"},{"id":"T5453","span":{"begin":1685,"end":1689},"obj":"PATO_0000386"},{"id":"T5454","span":{"begin":570,"end":574},"obj":"PATO_0000387"},{"id":"T5455","span":{"begin":617,"end":623},"obj":"PATO_0000701"},{"id":"T5456","span":{"begin":794,"end":798},"obj":"PATO_0002126"},{"id":"T5457","span":{"begin":1565,"end":1569},"obj":"PATO_0002126"},{"id":"T5458","span":{"begin":1226,"end":1234},"obj":"PATO_0000173"},{"id":"T5459","span":{"begin":1384,"end":1392},"obj":"PATO_0000173"},{"id":"T5460","span":{"begin":1731,"end":1739},"obj":"PATO_0000173"},{"id":"T5461","span":{"begin":1429,"end":1434},"obj":"PATO_0001736"},{"id":"T5462","span":{"begin":1439,"end":1445},"obj":"PATO_0001716"},{"id":"T5463","span":{"begin":1502,"end":1510},"obj":"PATO_0001230"},{"id":"T5464","span":{"begin":1529,"end":1539},"obj":"PATO_0001031"}],"text":"6. Conclusions\nA dental implant system is a typical and excellent example of integrated product using multiple disciplines including surface science and technology, surface modification and surface physics and chemistry. The success and longevity of dental implants are strongly governed by surface characteristics. We have been reviewing approximately 500 relevant articles and found that there are certain factors that successful implants must possess to accommodate the ossteointegation. They are (i) biological compatibility not to be toxic to surrounding hard and soft tissues, (ii) mechanical compatibility to smooth transfer the stress between the placed implant root and receiving hard tissue, and (iii) morphological compatibility to accommodate the surface rugophilicity and promote bony cell growth [462].\nFigure 2 illustrates a schematic and conceptual Ti implant that possesses a gradual function of mechanical and biological behaviors, so that mechanical compatibility and biological compatibility can be realized.\nSome of ever-progressing manufacturing technologies as well as tissue engineering can be applied to fabricate dental implants. We are proposing a novel dental implant system, based on the gradual function design concept and aforementioned three major requirements for successful dental implant systems. Accordingly, new dental implant possesses two-fold function; (1) core portion of implant should solid and strong enough to bear biomechanical load and is gradually less strength with less modulus elasticity to fully accommodate the bony cell adaption at case portion of implant, and (2) such case portion’s characteristics could be suitable to growing hard tissue while core protion has still same function as those for adult patients."}