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PMC:2806624 / 5294-5713 JSONTXT

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pmc-enju-pas

Id Subject Object Predicate Lexical cue
T1942 0-4 PRP denotes They
T1943 5-12 VB denotes include
T1944 13-16 DT denotes the
T1945 17-24 JJ denotes crucial
T1946 25-32 NN denotes choices
T1947 33-40 IN denotes between
T1948 41-51 JJ denotes cell-cycle
T1949 52-56 NN denotes exit
T1950 57-60 CC denotes and
T1951 61-70 JJ denotes continued
T1952 71-84 NN denotes proliferation
T1953 84-85 -COMMA- denotes ,
T1954 86-88 RB denotes as
T1955 89-93 RB denotes well
T1956 94-96 IN denotes as
T1957 97-104 IN denotes between
T1958 105-109 NN denotes cell
T1959 110-125 NN denotes differentiation
T1960 126-129 CC denotes and
T1961 130-142 NN denotes self-renewal
T1962 143-144 -LRB- denotes (
T1963 144-149 NNP denotes Blyth
T1964 150-152 FW denotes et
T1965 153-156 FW denotes al.
T1966 156-157 -COMMA- denotes ,
T1967 158-162 CD denotes 2005
T1968 162-163 -RRB- denotes )
T1969 163-172 NN denotes . Because
T1970 173-175 IN denotes of
T1971 176-179 DT denotes the
T1972 180-191 NN denotes involvement
T1973 192-194 IN denotes of
T1974 195-199 NN denotes RUNX
T1975 200-209 NN denotes mutations
T1976 210-212 IN denotes in
T1977 213-222 JJ denotes different
T1978 223-233 JJ denotes autoimmune
T1979 234-242 NN denotes diseases
T1980 243-246 CC denotes and
T1981 247-250 DT denotes the
T1982 251-256 JJ denotes known
T1983 257-268 NN denotes interaction
T1984 269-273 IN denotes with
T1985 274-279 NN denotes TGF-β
T1986 279-280 -COMMA- denotes ,
T1987 281-283 PRP denotes we
T1988 284-296 VB denotes investigated
T1989 297-300 DT denotes the
T1990 301-307 NN denotes impact
T1991 308-310 IN denotes of
T1992 311-316 NN denotes RUNX1
T1993 317-320 CC denotes and
T1994 321-326 NN denotes RUNX3
T1995 327-329 IN denotes on
T1996 330-333 DT denotes the
T1997 334-344 NN denotes expression
T1998 345-347 IN denotes of
T1999 348-353 NN denotes FOXP3
T2000 354-357 CC denotes and
T2001 358-370 RB denotes subsequently
T2002 371-373 IN denotes on
T2003 374-377 DT denotes the
T2004 378-389 NN denotes development
T2005 390-393 CC denotes and
T2006 394-402 NN denotes function
T2007 403-405 IN denotes of
T2008 406-408 NN denotes iT
T2009 409-412 NN denotes reg
T2010 413-418 NN denotes cells
R1522 T1942 T1943 arg1Of They,include
R1523 T1943 T1986 arg1Of include,","
R1524 T1946 T1943 arg2Of choices,include
R1525 T1946 T1944 arg1Of choices,the
R1526 T1946 T1945 arg1Of choices,crucial
R1527 T1946 T1947 arg1Of choices,between
R1528 T1946 T1957 arg1Of choices,between
R1529 T1947 T1956 arg1Of between,as
R1530 T1949 T1948 arg1Of exit,cell-cycle
R1531 T1949 T1950 arg1Of exit,and
R1532 T1950 T1947 arg2Of and,between
R1533 T1952 T1950 arg2Of proliferation,and
R1534 T1952 T1951 arg1Of proliferation,continued
R1535 T1956 T1953 arg1Of as,","
R1536 T1956 T1954 arg1Of as,as
R1537 T1956 T1955 arg1Of as,well
R1538 T1957 T1956 arg2Of between,as
R1539 T1959 T1960 arg1Of differentiation,and
R1540 T1960 T1957 arg2Of and,between
R1541 T1960 T1958 arg1Of and,cell
R1542 T1961 T1960 arg2Of self-renewal,and
R1543 T1963 T1962 arg2Of Blyth,(
R1544 T1963 T1964 arg1Of Blyth,et
R1545 T1963 T1965 arg1Of Blyth,al.
R1546 T1963 T1966 arg1Of Blyth,","
R1547 T1967 T1966 arg2Of 2005,","
R1548 T1968 T1962 arg3Of ),(
R1549 T1969 T1957 arg3Of ". Because",between
R1550 T1969 T1962 arg1Of ". Because",(
R1551 T1969 T1970 arg1Of ". Because",of
R1552 T1972 T1971 arg1Of involvement,the
R1553 T1972 T1973 arg1Of involvement,of
R1554 T1972 T1976 arg1Of involvement,in
R1555 T1972 T1980 arg1Of involvement,and
R1556 T1975 T1973 arg2Of mutations,of
R1557 T1975 T1974 arg1Of mutations,RUNX
R1558 T1979 T1976 arg2Of diseases,in
R1559 T1979 T1977 arg1Of diseases,different
R1560 T1979 T1978 arg1Of diseases,autoimmune
R1561 T1980 T1970 arg2Of and,of
R1562 T1983 T1980 arg2Of interaction,and
R1563 T1983 T1981 arg1Of interaction,the
R1564 T1983 T1982 arg1Of interaction,known
R1565 T1983 T1984 arg1Of interaction,with
R1566 T1985 T1984 arg2Of TGF-β,with
R1567 T1986 T1995 arg1Of ",",on
R1568 T1986 T2001 arg1Of ",",subsequently
R1569 T1986 T2002 arg1Of ",",on
R1570 T1987 T1988 arg1Of we,investigated
R1571 T1988 T1986 arg2Of investigated,","
R1572 T1990 T1988 arg2Of impact,investigated
R1573 T1990 T1989 arg1Of impact,the
R1574 T1990 T1991 arg1Of impact,of
R1575 T1992 T1993 arg1Of RUNX1,and
R1576 T1993 T1991 arg2Of and,of
R1577 T1994 T1993 arg2Of RUNX3,and
R1578 T1995 T2000 arg1Of on,and
R1579 T1997 T1995 arg2Of expression,on
R1580 T1997 T1996 arg1Of expression,the
R1581 T1997 T1998 arg1Of expression,of
R1582 T1999 T1998 arg2Of FOXP3,of
R1583 T2001 T2000 arg2Of subsequently,and
R1584 T2004 T2005 arg1Of development,and
R1585 T2005 T2002 arg2Of and,on
R1586 T2005 T2003 arg1Of and,the
R1587 T2005 T2007 arg1Of and,of
R1588 T2006 T2005 arg2Of function,and
R1589 T2010 T2007 arg2Of cells,of
R1590 T2010 T2008 arg1Of cells,iT
R1591 T2010 T2009 arg1Of cells,reg

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T2792 0-4 PRP denotes They
T2793 5-12 VBP denotes include
T2794 13-16 DT denotes the
T2795 17-24 JJ denotes crucial
T2796 25-32 NNS denotes choices
T2797 33-40 IN denotes between
T2798 41-51 JJ denotes cell-cycle
T2799 52-56 NN denotes exit
T2800 57-60 CC denotes and
T2801 61-70 VBD denotes continued
T2802 71-84 NN denotes proliferation
T2803 84-85 , denotes ,
T2804 86-88 RB denotes as
T2805 89-93 RB denotes well
T2806 94-96 IN denotes as
T2807 97-104 IN denotes between
T2808 105-109 NN denotes cell
T2809 110-125 NN denotes differentiation
T2810 126-129 CC denotes and
T2811 130-142 JJ denotes self-renewal
T2812 143-144 -LRB- denotes (
T2813 144-149 NNP denotes Blyth
T2814 150-152 FW denotes et
T2815 153-156 FW denotes al.
T2816 156-157 , denotes ,
T2817 158-162 CD denotes 2005
T2818 162-163 -RRB- denotes )
T2819 163-164 . denotes .
T2820 165-172 IN denotes Because
T2821 173-175 IN denotes of
T2822 176-179 DT denotes the
T2823 180-191 NN denotes involvement
T2824 192-194 IN denotes of
T2825 195-199 NNP denotes RUNX
T2826 200-209 NNS denotes mutations
T2827 210-212 IN denotes in
T2828 213-222 JJ denotes different
T2829 223-233 JJ denotes autoimmune
T2830 234-242 NNS denotes diseases
T2831 243-246 CC denotes and
T2832 247-250 DT denotes the
T2833 251-256 VBN denotes known
T2834 257-268 NN denotes interaction
T2835 269-273 IN denotes with
T2836 274-279 NNP denotes TGF-β
T2837 279-280 , denotes ,
T2838 281-283 PRP denotes we
T2839 284-296 VBD denotes investigated
T2840 297-300 DT denotes the
T2841 301-307 NN denotes impact
T2842 308-310 IN denotes of
T2843 311-316 NNP denotes RUNX1
T2844 317-320 CC denotes and
T2845 321-326 NNP denotes RUNX3
T2846 327-329 IN denotes on
T2847 330-333 DT denotes the
T2848 334-344 NN denotes expression
T2849 345-347 IN denotes of
T2850 348-353 CD denotes FOXP3
T2851 354-357 CC denotes and
T2852 358-370 RB denotes subsequently
T2853 371-373 IN denotes on
T2854 374-377 DT denotes the
T2855 378-389 NN denotes development
T2856 390-393 CC denotes and
T2857 394-402 NN denotes function
T2858 403-405 IN denotes of
T2859 406-408 NNP denotes iT
T2860 409-412 NN denotes reg
T2861 413-418 NNS denotes cells
T2862 418-419 . denotes .
R2294 T2801 T2802 amod continued,proliferation
R2296 T2802 T2799 conj proliferation,exit
R2297 T2803 T2799 punct ",",exit
R2298 T2804 T2806 advmod as,as
R2300 T2805 T2806 advmod well,as
R2301 T2806 T2799 cc as,exit
R2303 T2807 T2799 prep between,exit
R2304 T2808 T2809 compound cell,differentiation
R2306 T2809 T2807 pobj differentiation,between
R2307 T2810 T2809 cc and,differentiation
R2309 T2811 T2809 conj self-renewal,differentiation
R2310 T2812 T2815 punct (,al.
R2311 T2813 T2815 compound Blyth,al.
R2312 T2814 T2815 nmod et,al.
R2313 T2815 T2799 conj al.,exit
R2314 T2816 T2815 punct ",",al.
R2316 T2817 T2815 npadvmod 2005,al.
R2317 T2818 T2815 punct ),al.
R2318 T2819 T2793 punct .,include
R2320 T2820 T2839 prep Because,investigated
R2321 T2821 T2820 pcomp of,Because
R2322 T2822 T2823 det the,involvement
R2324 T2823 T2820 pobj involvement,Because
R2325 T2824 T2823 prep of,involvement
R2326 T2825 T2826 compound RUNX,mutations
R2327 T2838 T2839 nsubj we,investigated
R2328 T2826 T2824 pobj mutations,of
R2329 T2827 T2826 prep in,mutations
R2330 T2839 T2839 ROOT investigated,investigated
R2331 T2828 T2830 amod different,diseases
R2332 T2829 T2830 amod autoimmune,diseases
R2333 T2830 T2827 pobj diseases,in
R2334 T2831 T2830 cc and,diseases
R2335 T2840 T2841 det the,impact
R2336 T2832 T2834 det the,interaction
R2337 T2833 T2834 amod known,interaction
R2338 T2841 T2839 dobj impact,investigated
R2339 T2834 T2823 conj interaction,involvement
R2340 T2835 T2834 prep with,interaction
R2341 T2836 T2835 pobj TGF-β,with
R2342 T2842 T2841 prep of,impact
R2343 T2837 T2839 punct ",",investigated
R2344 T2843 T2842 pobj RUNX1,of
R2345 T2844 T2843 cc and,RUNX1
R2346 T2845 T2843 conj RUNX3,RUNX1
R2347 T2846 T2841 prep on,impact
R2348 T2847 T2848 det the,expression
R2349 T2848 T2846 pobj expression,on
R2350 T2849 T2848 prep of,expression
R2351 T2850 T2849 pobj FOXP3,of
R2353 T2851 T2850 cc and,FOXP3
R2356 T2852 T2839 advmod subsequently,investigated
R2358 T2853 T2839 prep on,investigated
R2361 T2854 T2855 det the,development
R2365 T2855 T2853 pobj development,on
R2367 T2856 T2855 cc and,development
R2371 T2857 T2855 conj function,development
R2375 T2858 T2855 prep of,development
R2384 T2859 T2861 compound iT,cells
R2390 T2860 T2861 compound reg,cells
R2393 T2861 T2858 pobj cells,of
R2394 T2862 T2839 punct .,investigated
R2281 T2792 T2793 nsubj They,include
R2282 T2793 T2793 ROOT include,include
R2283 T2794 T2796 det the,choices
R2285 T2795 T2796 amod crucial,choices
R2286 T2796 T2793 dobj choices,include
R2287 T2797 T2796 prep between,choices
R2289 T2798 T2799 amod cell-cycle,exit
R2290 T2799 T2797 pobj exit,between
R2292 T2800 T2799 cc and,exit

GO-BP

Id Subject Object Predicate Lexical cue
T2979 378-389 http://purl.obolibrary.org/obo/GO_0032502 denotes development
T2984 105-125 http://purl.obolibrary.org/obo/GO_0030154 denotes cell differentiation
T2994 41-51 http://purl.obolibrary.org/obo/GO_0007049 denotes cell-cycle

GO-CC

Id Subject Object Predicate Lexical cue
T3015 413-418 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

sentences

Id Subject Object Predicate Lexical cue
T1294 0-419 Sentence denotes They include the crucial choices between cell-cycle exit and continued proliferation, as well as between cell differentiation and self-renewal (Blyth et al., 2005). Because of the involvement of RUNX mutations in different autoimmune diseases and the known interaction with TGF-β, we investigated the impact of RUNX1 and RUNX3 on the expression of FOXP3 and subsequently on the development and function of iT reg cells.
T33 0-164 Sentence denotes They include the crucial choices between cell-cycle exit and continued proliferation, as well as between cell differentiation and self-renewal (Blyth et al., 2005).
T34 165-419 Sentence denotes Because of the involvement of RUNX mutations in different autoimmune diseases and the known interaction with TGF-β, we investigated the impact of RUNX1 and RUNX3 on the expression of FOXP3 and subsequently on the development and function of iT reg cells.

events-check-again

Id Subject Object Predicate Lexical cue Speculation
T3272 195-199 Protein denotes RUNX
T3273 257-268 Binding denotes interaction
T3274 274-279 Protein denotes TGF-β
T3275 301-307 Regulation denotes impact true
T3276 301-307 Regulation denotes impact true
T3277 311-316 Protein denotes RUNX1
T3278 321-326 Protein denotes RUNX3
T3279 334-344 Gene_expression denotes expression
T3280 348-353 Protein denotes FOXP3
R2567 T3277 T3276 causeOf RUNX1,impact
R2569 T3278 T3275 causeOf RUNX3,impact
R2570 T3279 T3276 themeOf expression,impact
R2571 T3279 T3275 themeOf expression,impact
R2572 T3280 T3279 themeOf FOXP3,expression
R2584 T3272 T3273 themeOf RUNX,interaction
R2585 T3274 T3273 themeOf TGF-β,interaction

bionlp-st-ge-2016-reference-tees

Id Subject Object Predicate Lexical cue
T3109 195-209 Protein denotes RUNX mutations
T3110 274-279 Protein denotes TGF-β
T3111 311-316 Protein denotes RUNX1
T3112 321-326 Protein denotes RUNX3
T3113 348-353 Protein denotes FOXP3
T3114 406-412 Protein denotes iT reg
T3115 257-268 Binding denotes interaction
T3116 334-344 Gene_expression denotes expression
T3117 301-307 Regulation denotes impact
T3118 301-307 Regulation denotes impact
R2469 T3110 T3115 themeOf TGF-β,interaction
R2471 T3111 T3117 causeOf RUNX1,impact
R2472 T3112 T3118 causeOf RUNX3,impact
R2474 T3113 T3116 themeOf FOXP3,expression
R2478 T3116 T3117 themeOf expression,impact
R2479 T3116 T3118 themeOf expression,impact

bionlp-st-ge-2016-reference

Id Subject Object Predicate Lexical cue Speculation
T1262 195-199 Protein denotes RUNX
T1263 257-268 Binding denotes interaction
T1264 274-279 Protein denotes TGF-β
T1265 301-307 Regulation denotes impact true
T1266 301-307 Regulation denotes impact true
T1267 311-316 Protein denotes RUNX1
T1268 321-326 Protein denotes RUNX3
T1269 334-344 Gene_expression denotes expression
T1270 348-353 Protein denotes FOXP3
R867 T1262 T1263 themeOf RUNX,interaction
R868 T1264 T1263 themeOf TGF-β,interaction
R869 T1267 T1266 causeOf RUNX1,impact
R870 T1268 T1265 causeOf RUNX3,impact
R871 T1269 T1266 themeOf expression,impact
R872 T1269 T1265 themeOf expression,impact
R873 T1270 T1269 themeOf FOXP3,expression

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T2085 195-199 Q13950 denotes RUNX
T2086 195-199 Q01196 denotes RUNX
T2087 195-199 Q13761 denotes RUNX
T2088 274-279 P01137 denotes TGF-β
T2089 311-316 Q01196 denotes RUNX1
T2090 321-326 Q13761 denotes RUNX3
T2091 348-353 Q9BZS1 denotes FOXP3

test2

Id Subject Object Predicate Lexical cue
T1178 195-199 Protein denotes RUNX
T1179 257-268 Binding denotes interaction
T1180 274-279 Protein denotes TGF-β
T1181 301-307 Regulation denotes impact
T1182 311-316 Protein denotes RUNX1
T1183 321-326 Protein denotes RUNX3
T1184 334-344 Gene_expression denotes expression
T1185 348-353 Protein denotes FOXP3
R818 T1178 T1179 themeOf RUNX,interaction
R819 T1180 T1179 themeOf TGF-β,interaction
R820 T1182 T1181 causeOf RUNX1,impact
R821 T1183 T1181 causeOf RUNX3,impact
R822 T1184 T1181 themeOf expression,impact
R823 T1185 T1184 themeOf FOXP3,expression