PMC:2791889 / 17886-18078 JSONTXT

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    bionlp-st-ge-2016-uniprot

    {"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T9883","span":{"begin":29,"end":34},"obj":"P22301"},{"id":"T9884","span":{"begin":96,"end":101},"obj":"P29459"},{"id":"T9885","span":{"begin":96,"end":101},"obj":"P29460"},{"id":"T9886","span":{"begin":111,"end":115},"obj":"P27361"},{"id":"T9887","span":{"begin":120,"end":124},"obj":"P28482"},{"id":"T9888","span":{"begin":166,"end":169},"obj":"O15264"},{"id":"T9889","span":{"begin":166,"end":169},"obj":"Q16539"},{"id":"T9890","span":{"begin":166,"end":169},"obj":"P53778"},{"id":"T9891","span":{"begin":166,"end":169},"obj":"Q15759"},{"id":"T9892","span":{"begin":177,"end":182},"obj":"P49841"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"Our data thus suggested that IL-10 production by Th1 cells in response to high antigen dose and IL-12 requires ERK1 and ERK2 signaling, but not the activation of the p38 or the GSK3β pathways."}

    bionlp-st-ge-2016-reference

    {"project":"bionlp-st-ge-2016-reference","denotations":[{"id":"T9368","span":{"begin":29,"end":34},"obj":"Protein"},{"id":"T9369","span":{"begin":35,"end":45},"obj":"Gene_expression"},{"id":"T9370","span":{"begin":59,"end":73},"obj":"Positive_regulation"},{"id":"T9371","span":{"begin":96,"end":101},"obj":"Protein"},{"id":"T9372","span":{"begin":102,"end":110},"obj":"Positive_regulation"},{"id":"T9373","span":{"begin":102,"end":110},"obj":"Positive_regulation"},{"id":"T9374","span":{"begin":111,"end":115},"obj":"Protein"},{"id":"T9375","span":{"begin":120,"end":124},"obj":"Protein"},{"id":"T9376","span":{"begin":148,"end":158},"obj":"Positive_regulation"},{"id":"T9377","span":{"begin":148,"end":158},"obj":"Positive_regulation"},{"id":"T9378","span":{"begin":166,"end":169},"obj":"Protein"},{"id":"T9379","span":{"begin":177,"end":182},"obj":"Protein"}],"relations":[{"id":"R7153","pred":"themeOf","subj":"T9368","obj":"T9369"},{"id":"R7154","pred":"themeOf","subj":"T9369","obj":"T9370"},{"id":"R7155","pred":"themeOf","subj":"T9370","obj":"T9372"},{"id":"R7156","pred":"themeOf","subj":"T9370","obj":"T9373"},{"id":"R7157","pred":"causeOf","subj":"T9371","obj":"T9370"},{"id":"R7160","pred":"causeOf","subj":"T9376","obj":"T9372"},{"id":"R7162","pred":"causeOf","subj":"T9377","obj":"T9373"},{"id":"R7164","pred":"themeOf","subj":"T9378","obj":"T9376"},{"id":"R7165","pred":"themeOf","subj":"T9379","obj":"T9377"}],"attributes":[{"id":"M170","pred":"Negation","subj":"T9373","obj":"true"},{"id":"M171","pred":"Speculation","subj":"T9373","obj":"true"},{"id":"M168","pred":"Negation","subj":"T9372","obj":"true"},{"id":"M169","pred":"Speculation","subj":"T9372","obj":"true"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Our data thus suggested that IL-10 production by Th1 cells in response to high antigen dose and IL-12 requires ERK1 and ERK2 signaling, but not the activation of the p38 or the GSK3β pathways."}

    pmc-enju-pas

    {"project":"pmc-enju-pas","denotations":[{"id":"T9799","span":{"begin":0,"end":3},"obj":"PRP-DOLLAR-"},{"id":"T9800","span":{"begin":4,"end":8},"obj":"NN"},{"id":"T9801","span":{"begin":9,"end":13},"obj":"RB"},{"id":"T9802","span":{"begin":14,"end":23},"obj":"VB"},{"id":"T9803","span":{"begin":24,"end":28},"obj":"IN"},{"id":"T9804","span":{"begin":29,"end":34},"obj":"NN"},{"id":"T9805","span":{"begin":35,"end":45},"obj":"NN"},{"id":"T9806","span":{"begin":46,"end":48},"obj":"IN"},{"id":"T9807","span":{"begin":49,"end":52},"obj":"NN"},{"id":"T9808","span":{"begin":53,"end":58},"obj":"NN"},{"id":"T9809","span":{"begin":59,"end":61},"obj":"IN"},{"id":"T9810","span":{"begin":62,"end":70},"obj":"NN"},{"id":"T9811","span":{"begin":71,"end":73},"obj":"TO"},{"id":"T9812","span":{"begin":74,"end":78},"obj":"JJ"},{"id":"T9813","span":{"begin":79,"end":86},"obj":"NN"},{"id":"T9814","span":{"begin":87,"end":91},"obj":"NN"},{"id":"T9815","span":{"begin":92,"end":95},"obj":"CC"},{"id":"T9816","span":{"begin":96,"end":101},"obj":"NN"},{"id":"T9817","span":{"begin":102,"end":110},"obj":"VB"},{"id":"T9818","span":{"begin":111,"end":115},"obj":"NN"},{"id":"T9819","span":{"begin":116,"end":119},"obj":"CC"},{"id":"T9820","span":{"begin":120,"end":124},"obj":"NN"},{"id":"T9821","span":{"begin":125,"end":134},"obj":"NN"},{"id":"T9822","span":{"begin":134,"end":135},"obj":"-COMMA-"},{"id":"T9823","span":{"begin":136,"end":139},"obj":"CC"},{"id":"T9824","span":{"begin":140,"end":143},"obj":"RB"},{"id":"T9825","span":{"begin":144,"end":147},"obj":"DT"},{"id":"T9826","span":{"begin":148,"end":158},"obj":"NN"},{"id":"T9827","span":{"begin":159,"end":161},"obj":"IN"},{"id":"T9828","span":{"begin":162,"end":165},"obj":"DT"},{"id":"T9829","span":{"begin":166,"end":169},"obj":"NN"},{"id":"T9830","span":{"begin":170,"end":172},"obj":"CC"},{"id":"T9831","span":{"begin":173,"end":176},"obj":"DT"},{"id":"T9832","span":{"begin":177,"end":182},"obj":"NN"},{"id":"T9833","span":{"begin":183,"end":191},"obj":"NN"}],"relations":[{"id":"R7579","pred":"arg1Of","subj":"T9800","obj":"T9799"},{"id":"R7580","pred":"arg1Of","subj":"T9800","obj":"T9802"},{"id":"R7581","pred":"arg1Of","subj":"T9802","obj":"T9801"},{"id":"R7582","pred":"arg1Of","subj":"T9805","obj":"T9804"},{"id":"R7583","pred":"arg1Of","subj":"T9805","obj":"T9806"},{"id":"R7584","pred":"arg1Of","subj":"T9805","obj":"T9817"},{"id":"R7585","pred":"arg2Of","subj":"T9808","obj":"T9806"},{"id":"R7586","pred":"arg1Of","subj":"T9808","obj":"T9807"},{"id":"R7587","pred":"arg1Of","subj":"T9808","obj":"T9809"},{"id":"R7588","pred":"arg2Of","subj":"T9810","obj":"T9809"},{"id":"R7589","pred":"arg1Of","subj":"T9810","obj":"T9811"},{"id":"R7590","pred":"arg1Of","subj":"T9814","obj":"T9812"},{"id":"R7591","pred":"arg1Of","subj":"T9814","obj":"T9813"},{"id":"R7592","pred":"arg1Of","subj":"T9814","obj":"T9815"},{"id":"R7593","pred":"arg2Of","subj":"T9815","obj":"T9811"},{"id":"R7594","pred":"arg2Of","subj":"T9816","obj":"T9815"},{"id":"R7595","pred":"arg2Of","subj":"T9817","obj":"T9802"},{"id":"R7596","pred":"arg1Of","subj":"T9817","obj":"T9803"},{"id":"R7597","pred":"arg1Of","subj":"T9818","obj":"T9819"},{"id":"R7598","pred":"arg1Of","subj":"T9819","obj":"T9823"},{"id":"R7599","pred":"arg2Of","subj":"T9821","obj":"T9819"},{"id":"R7600","pred":"arg1Of","subj":"T9821","obj":"T9820"},{"id":"R7601","pred":"arg2Of","subj":"T9823","obj":"T9817"},{"id":"R7602","pred":"arg1Of","subj":"T9823","obj":"T9822"},{"id":"R7603","pred":"arg1Of","subj":"T9823","obj":"T9824"},{"id":"R7604","pred":"arg2Of","subj":"T9826","obj":"T9823"},{"id":"R7605","pred":"arg1Of","subj":"T9826","obj":"T9825"},{"id":"R7606","pred":"arg1Of","subj":"T9826","obj":"T9827"},{"id":"R7607","pred":"arg1Of","subj":"T9829","obj":"T9828"},{"id":"R7608","pred":"arg1Of","subj":"T9829","obj":"T9830"},{"id":"R7609","pred":"arg2Of","subj":"T9830","obj":"T9827"},{"id":"R7610","pred":"arg2Of","subj":"T9833","obj":"T9830"},{"id":"R7611","pred":"arg1Of","subj":"T9833","obj":"T9831"},{"id":"R7612","pred":"arg1Of","subj":"T9833","obj":"T9832"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"text":"Our data thus suggested that IL-10 production by Th1 cells in response to high antigen dose and IL-12 requires ERK1 and ERK2 signaling, but not the activation of the p38 or the GSK3β pathways."}

    bionlp-st-ge-2016-spacy-parsed

    {"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T10332","span":{"begin":0,"end":3},"obj":"PRP$"},{"id":"T10333","span":{"begin":4,"end":8},"obj":"NNS"},{"id":"T10334","span":{"begin":9,"end":13},"obj":"RB"},{"id":"T10335","span":{"begin":14,"end":23},"obj":"VBD"},{"id":"T10336","span":{"begin":24,"end":28},"obj":"IN"},{"id":"T10337","span":{"begin":29,"end":34},"obj":"JJ"},{"id":"T10338","span":{"begin":35,"end":45},"obj":"NN"},{"id":"T10339","span":{"begin":46,"end":48},"obj":"IN"},{"id":"T10340","span":{"begin":49,"end":52},"obj":"JJ"},{"id":"T10341","span":{"begin":53,"end":58},"obj":"NNS"},{"id":"T10342","span":{"begin":59,"end":61},"obj":"IN"},{"id":"T10343","span":{"begin":62,"end":70},"obj":"NN"},{"id":"T10344","span":{"begin":71,"end":73},"obj":"TO"},{"id":"T10345","span":{"begin":74,"end":78},"obj":"JJ"},{"id":"T10346","span":{"begin":79,"end":86},"obj":"NN"},{"id":"T10347","span":{"begin":87,"end":91},"obj":"NN"},{"id":"T10348","span":{"begin":92,"end":95},"obj":"CC"},{"id":"T10349","span":{"begin":96,"end":101},"obj":"NN"},{"id":"T10350","span":{"begin":102,"end":110},"obj":"VBZ"},{"id":"T10351","span":{"begin":111,"end":115},"obj":"CD"},{"id":"T10352","span":{"begin":116,"end":119},"obj":"CC"},{"id":"T10353","span":{"begin":120,"end":124},"obj":"CD"},{"id":"T10354","span":{"begin":125,"end":134},"obj":"VBG"},{"id":"T10355","span":{"begin":134,"end":135},"obj":","},{"id":"T10356","span":{"begin":136,"end":139},"obj":"CC"},{"id":"T10357","span":{"begin":140,"end":143},"obj":"RB"},{"id":"T10358","span":{"begin":144,"end":147},"obj":"DT"},{"id":"T10359","span":{"begin":148,"end":158},"obj":"NN"},{"id":"T10360","span":{"begin":159,"end":161},"obj":"IN"},{"id":"T10361","span":{"begin":162,"end":165},"obj":"DT"},{"id":"T10362","span":{"begin":166,"end":169},"obj":"CD"},{"id":"T10363","span":{"begin":170,"end":172},"obj":"CC"},{"id":"T10364","span":{"begin":173,"end":176},"obj":"DT"},{"id":"T10365","span":{"begin":177,"end":182},"obj":"NNP"},{"id":"T10366","span":{"begin":183,"end":191},"obj":"NNS"},{"id":"T10367","span":{"begin":191,"end":192},"obj":"."}],"relations":[{"id":"R8070","pred":"ccomp","subj":"T10350","obj":"T10335"},{"id":"R8071","pred":"dobj","subj":"T10351","obj":"T10350"},{"id":"R8072","pred":"cc","subj":"T10352","obj":"T10351"},{"id":"R8073","pred":"conj","subj":"T10353","obj":"T10351"},{"id":"R8074","pred":"advcl","subj":"T10354","obj":"T10350"},{"id":"R8075","pred":"punct","subj":"T10355","obj":"T10354"},{"id":"R8076","pred":"cc","subj":"T10356","obj":"T10354"},{"id":"R8077","pred":"neg","subj":"T10357","obj":"T10359"},{"id":"R8078","pred":"det","subj":"T10358","obj":"T10359"},{"id":"R8079","pred":"conj","subj":"T10359","obj":"T10354"},{"id":"R8080","pred":"prep","subj":"T10360","obj":"T10359"},{"id":"R8081","pred":"det","subj":"T10361","obj":"T10362"},{"id":"R8082","pred":"pobj","subj":"T10362","obj":"T10360"},{"id":"R8083","pred":"cc","subj":"T10363","obj":"T10362"},{"id":"R8084","pred":"det","subj":"T10364","obj":"T10366"},{"id":"R8085","pred":"compound","subj":"T10365","obj":"T10366"},{"id":"R8086","pred":"conj","subj":"T10366","obj":"T10362"},{"id":"R8087","pred":"punct","subj":"T10367","obj":"T10335"},{"id":"R8052","pred":"poss","subj":"T10332","obj":"T10333"},{"id":"R8053","pred":"nsubj","subj":"T10333","obj":"T10335"},{"id":"R8054","pred":"advmod","subj":"T10334","obj":"T10335"},{"id":"R8055","pred":"ROOT","subj":"T10335","obj":"T10335"},{"id":"R8056","pred":"mark","subj":"T10336","obj":"T10350"},{"id":"R8057","pred":"amod","subj":"T10337","obj":"T10338"},{"id":"R8058","pred":"nsubj","subj":"T10338","obj":"T10350"},{"id":"R8059","pred":"prep","subj":"T10339","obj":"T10338"},{"id":"R8060","pred":"amod","subj":"T10340","obj":"T10341"},{"id":"R8061","pred":"pobj","subj":"T10341","obj":"T10339"},{"id":"R8062","pred":"prep","subj":"T10342","obj":"T10338"},{"id":"R8063","pred":"pobj","subj":"T10343","obj":"T10342"},{"id":"R8064","pred":"prep","subj":"T10344","obj":"T10343"},{"id":"R8065","pred":"amod","subj":"T10345","obj":"T10347"},{"id":"R8066","pred":"compound","subj":"T10346","obj":"T10347"},{"id":"R8067","pred":"pobj","subj":"T10347","obj":"T10344"},{"id":"R8068","pred":"cc","subj":"T10348","obj":"T10347"},{"id":"R8069","pred":"nsubj","subj":"T10349","obj":"T10350"}],"text":"Our data thus suggested that IL-10 production by Th1 cells in response to high antigen dose and IL-12 requires ERK1 and ERK2 signaling, but not the activation of the p38 or the GSK3β pathways."}

    GO-BP

    {"project":"GO-BP","denotations":[{"id":"T10384","span":{"begin":29,"end":45},"obj":"http://purl.obolibrary.org/obo/GO_0032653"},{"id":"T10389","span":{"begin":29,"end":45},"obj":"http://purl.obolibrary.org/obo/GO_0032613"},{"id":"T10413","span":{"begin":125,"end":134},"obj":"http://purl.obolibrary.org/obo/GO_0023052"},{"id":"T10420","span":{"begin":111,"end":134},"obj":"http://purl.obolibrary.org/obo/GO_0070371"}],"text":"Our data thus suggested that IL-10 production by Th1 cells in response to high antigen dose and IL-12 requires ERK1 and ERK2 signaling, but not the activation of the p38 or the GSK3β pathways."}

    GO-MF

    {"project":"GO-MF","denotations":[{"id":"T10428","span":{"begin":29,"end":34},"obj":"http://purl.obolibrary.org/obo/GO_0005141"},{"id":"T10448","span":{"begin":96,"end":101},"obj":"http://purl.obolibrary.org/obo/GO_0005143"}],"text":"Our data thus suggested that IL-10 production by Th1 cells in response to high antigen dose and IL-12 requires ERK1 and ERK2 signaling, but not the activation of the p38 or the GSK3β pathways."}

    GO-CC

    {"project":"GO-CC","denotations":[{"id":"T10462","span":{"begin":53,"end":58},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"Our data thus suggested that IL-10 production by Th1 cells in response to high antigen dose and IL-12 requires ERK1 and ERK2 signaling, but not the activation of the p38 or the GSK3β pathways."}

    sentences

    {"project":"sentences","denotations":[{"id":"T9391","span":{"begin":0,"end":192},"obj":"Sentence"},{"id":"T92","span":{"begin":0,"end":192},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Our data thus suggested that IL-10 production by Th1 cells in response to high antigen dose and IL-12 requires ERK1 and ERK2 signaling, but not the activation of the p38 or the GSK3β pathways."}

    events-check-again

    {"project":"events-check-again","denotations":[{"id":"T10785","span":{"begin":29,"end":34},"obj":"Protein"},{"id":"T10786","span":{"begin":35,"end":45},"obj":"Gene_expression"},{"id":"T10787","span":{"begin":59,"end":73},"obj":"Positive_regulation"},{"id":"T10788","span":{"begin":96,"end":101},"obj":"Protein"},{"id":"T10789","span":{"begin":102,"end":110},"obj":"Positive_regulation"},{"id":"T10790","span":{"begin":102,"end":110},"obj":"Positive_regulation"},{"id":"T10791","span":{"begin":111,"end":115},"obj":"Protein"},{"id":"T10792","span":{"begin":120,"end":124},"obj":"Protein"},{"id":"T10793","span":{"begin":148,"end":158},"obj":"Positive_regulation"},{"id":"T10794","span":{"begin":148,"end":158},"obj":"Positive_regulation"},{"id":"T10795","span":{"begin":166,"end":169},"obj":"Protein"},{"id":"T10796","span":{"begin":177,"end":182},"obj":"Protein"}],"relations":[{"id":"R8324","pred":"themeOf","subj":"T10785","obj":"T10786"},{"id":"R8325","pred":"themeOf","subj":"T10786","obj":"T10787"},{"id":"R8326","pred":"themeOf","subj":"T10787","obj":"T10789"},{"id":"R8327","pred":"themeOf","subj":"T10787","obj":"T10790"},{"id":"R8328","pred":"causeOf","subj":"T10788","obj":"T10787"},{"id":"R8331","pred":"causeOf","subj":"T10793","obj":"T10789"},{"id":"R8333","pred":"causeOf","subj":"T10794","obj":"T10790"},{"id":"R8335","pred":"themeOf","subj":"T10795","obj":"T10793"},{"id":"R8336","pred":"themeOf","subj":"T10796","obj":"T10794"}],"attributes":[{"id":"M195","pred":"Negation","subj":"T10789","obj":"true"},{"id":"M196","pred":"Speculation","subj":"T10789","obj":"true"},{"id":"M197","pred":"Negation","subj":"T10790","obj":"true"},{"id":"M198","pred":"Speculation","subj":"T10790","obj":"true"}],"text":"Our data thus suggested that IL-10 production by Th1 cells in response to high antigen dose and IL-12 requires ERK1 and ERK2 signaling, but not the activation of the p38 or the GSK3β pathways."}

    bionlp-st-ge-2016-reference-tees

    {"project":"bionlp-st-ge-2016-reference-tees","denotations":[{"id":"T10877","span":{"begin":96,"end":101},"obj":"Protein"},{"id":"T10878","span":{"begin":111,"end":115},"obj":"Protein"},{"id":"T10879","span":{"begin":120,"end":124},"obj":"Protein"},{"id":"T10880","span":{"begin":166,"end":169},"obj":"Protein"},{"id":"T10881","span":{"begin":177,"end":182},"obj":"Protein"},{"id":"T10882","span":{"begin":148,"end":158},"obj":"Positive_regulation"},{"id":"T10883","span":{"begin":148,"end":158},"obj":"Positive_regulation"}],"relations":[{"id":"R8380","pred":"themeOf","subj":"T10880","obj":"T10882"},{"id":"R8381","pred":"themeOf","subj":"T10881","obj":"T10883"}],"text":"Our data thus suggested that IL-10 production by Th1 cells in response to high antigen dose and IL-12 requires ERK1 and ERK2 signaling, but not the activation of the p38 or the GSK3β pathways."}

    test2

    {"project":"test2","denotations":[{"id":"T9259","span":{"begin":29,"end":34},"obj":"Protein"},{"id":"T9260","span":{"begin":35,"end":45},"obj":"Gene_expression"},{"id":"T9261","span":{"begin":59,"end":73},"obj":"Positive_regulation"},{"id":"T9262","span":{"begin":74,"end":78},"obj":"Positive_regulation"},{"id":"T9263","span":{"begin":96,"end":101},"obj":"Protein"},{"id":"T9264","span":{"begin":102,"end":110},"obj":"Positive_regulation"},{"id":"T9265","span":{"begin":111,"end":115},"obj":"Protein"},{"id":"T9266","span":{"begin":120,"end":124},"obj":"Protein"},{"id":"T9267","span":{"begin":148,"end":158},"obj":"Positive_regulation"},{"id":"T9268","span":{"begin":166,"end":169},"obj":"Protein"},{"id":"T9269","span":{"begin":177,"end":182},"obj":"Protein"}],"relations":[{"id":"R7074","pred":"themeOf","subj":"T9259","obj":"T9260"},{"id":"R7075","pred":"themeOf","subj":"T9260","obj":"T9264"},{"id":"R7076","pred":"themeOf","subj":"T9260","obj":"T9261"},{"id":"R7077","pred":"themeOf","subj":"T9261","obj":"T9264"},{"id":"R7078","pred":"causeOf","subj":"T9262","obj":"T9261"},{"id":"R7079","pred":"causeOf","subj":"T9263","obj":"T9261"},{"id":"R7080","pred":"causeOf","subj":"T9267","obj":"T9264"},{"id":"R7081","pred":"themeOf","subj":"T9268","obj":"T9267"},{"id":"R7082","pred":"themeOf","subj":"T9269","obj":"T9267"}],"text":"Our data thus suggested that IL-10 production by Th1 cells in response to high antigen dose and IL-12 requires ERK1 and ERK2 signaling, but not the activation of the p38 or the GSK3β pathways."}