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PMC:2791889 / 17886-18078
Annnotations
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9883 | 29-34 | P22301 | denotes | IL-10 |
T9884 | 96-101 | P29459 | denotes | IL-12 |
T9885 | 96-101 | P29460 | denotes | IL-12 |
T9886 | 111-115 | P27361 | denotes | ERK1 |
T9887 | 120-124 | P28482 | denotes | ERK2 |
T9888 | 166-169 | O15264 | denotes | p38 |
T9889 | 166-169 | Q16539 | denotes | p38 |
T9890 | 166-169 | P53778 | denotes | p38 |
T9891 | 166-169 | Q15759 | denotes | p38 |
T9892 | 177-182 | P49841 | denotes | GSK3β |
bionlp-st-ge-2016-reference
Id | Subject | Object | Predicate | Lexical cue | Negation | Speculation |
---|---|---|---|---|---|---|
T9368 | 29-34 | Protein | denotes | IL-10 | ||
T9369 | 35-45 | Gene_expression | denotes | production | ||
T9370 | 59-73 | Positive_regulation | denotes | in response to | ||
T9371 | 96-101 | Protein | denotes | IL-12 | ||
T9372 | 102-110 | Positive_regulation | denotes | requires | true | true |
T9373 | 102-110 | Positive_regulation | denotes | requires | true | true |
T9374 | 111-115 | Protein | denotes | ERK1 | ||
T9375 | 120-124 | Protein | denotes | ERK2 | ||
T9376 | 148-158 | Positive_regulation | denotes | activation | ||
T9377 | 148-158 | Positive_regulation | denotes | activation | ||
T9378 | 166-169 | Protein | denotes | p38 | ||
T9379 | 177-182 | Protein | denotes | GSK3β | ||
R7153 | T9368 | T9369 | themeOf | IL-10,production | ||
R7154 | T9369 | T9370 | themeOf | production,in response to | ||
R7155 | T9370 | T9372 | themeOf | in response to,requires | ||
R7156 | T9370 | T9373 | themeOf | in response to,requires | ||
R7157 | T9371 | T9370 | causeOf | IL-12,in response to | ||
R7160 | T9376 | T9372 | causeOf | activation,requires | ||
R7162 | T9377 | T9373 | causeOf | activation,requires | ||
R7164 | T9378 | T9376 | themeOf | p38,activation | ||
R7165 | T9379 | T9377 | themeOf | GSK3β,activation |
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9799 | 0-3 | PRP-DOLLAR- | denotes | Our |
T9800 | 4-8 | NN | denotes | data |
T9801 | 9-13 | RB | denotes | thus |
T9802 | 14-23 | VB | denotes | suggested |
T9803 | 24-28 | IN | denotes | that |
T9804 | 29-34 | NN | denotes | IL-10 |
T9805 | 35-45 | NN | denotes | production |
T9806 | 46-48 | IN | denotes | by |
T9807 | 49-52 | NN | denotes | Th1 |
T9808 | 53-58 | NN | denotes | cells |
T9809 | 59-61 | IN | denotes | in |
T9810 | 62-70 | NN | denotes | response |
T9811 | 71-73 | TO | denotes | to |
T9812 | 74-78 | JJ | denotes | high |
T9813 | 79-86 | NN | denotes | antigen |
T9814 | 87-91 | NN | denotes | dose |
T9815 | 92-95 | CC | denotes | and |
T9816 | 96-101 | NN | denotes | IL-12 |
T9817 | 102-110 | VB | denotes | requires |
T9818 | 111-115 | NN | denotes | ERK1 |
T9819 | 116-119 | CC | denotes | and |
T9820 | 120-124 | NN | denotes | ERK2 |
T9821 | 125-134 | NN | denotes | signaling |
T9822 | 134-135 | -COMMA- | denotes | , |
T9823 | 136-139 | CC | denotes | but |
T9824 | 140-143 | RB | denotes | not |
T9825 | 144-147 | DT | denotes | the |
T9826 | 148-158 | NN | denotes | activation |
T9827 | 159-161 | IN | denotes | of |
T9828 | 162-165 | DT | denotes | the |
T9829 | 166-169 | NN | denotes | p38 |
T9830 | 170-172 | CC | denotes | or |
T9831 | 173-176 | DT | denotes | the |
T9832 | 177-182 | NN | denotes | GSK3β |
T9833 | 183-191 | NN | denotes | pathways |
R7579 | T9800 | T9799 | arg1Of | data,Our |
R7580 | T9800 | T9802 | arg1Of | data,suggested |
R7581 | T9802 | T9801 | arg1Of | suggested,thus |
R7582 | T9805 | T9804 | arg1Of | production,IL-10 |
R7583 | T9805 | T9806 | arg1Of | production,by |
R7584 | T9805 | T9817 | arg1Of | production,requires |
R7585 | T9808 | T9806 | arg2Of | cells,by |
R7586 | T9808 | T9807 | arg1Of | cells,Th1 |
R7587 | T9808 | T9809 | arg1Of | cells,in |
R7588 | T9810 | T9809 | arg2Of | response,in |
R7589 | T9810 | T9811 | arg1Of | response,to |
R7590 | T9814 | T9812 | arg1Of | dose,high |
R7591 | T9814 | T9813 | arg1Of | dose,antigen |
R7592 | T9814 | T9815 | arg1Of | dose,and |
R7593 | T9815 | T9811 | arg2Of | and,to |
R7594 | T9816 | T9815 | arg2Of | IL-12,and |
R7595 | T9817 | T9802 | arg2Of | requires,suggested |
R7596 | T9817 | T9803 | arg1Of | requires,that |
R7597 | T9818 | T9819 | arg1Of | ERK1,and |
R7598 | T9819 | T9823 | arg1Of | and,but |
R7599 | T9821 | T9819 | arg2Of | signaling,and |
R7600 | T9821 | T9820 | arg1Of | signaling,ERK2 |
R7601 | T9823 | T9817 | arg2Of | but,requires |
R7602 | T9823 | T9822 | arg1Of | but,"," |
R7603 | T9823 | T9824 | arg1Of | but,not |
R7604 | T9826 | T9823 | arg2Of | activation,but |
R7605 | T9826 | T9825 | arg1Of | activation,the |
R7606 | T9826 | T9827 | arg1Of | activation,of |
R7607 | T9829 | T9828 | arg1Of | p38,the |
R7608 | T9829 | T9830 | arg1Of | p38,or |
R7609 | T9830 | T9827 | arg2Of | or,of |
R7610 | T9833 | T9830 | arg2Of | pathways,or |
R7611 | T9833 | T9831 | arg1Of | pathways,the |
R7612 | T9833 | T9832 | arg1Of | pathways,GSK3β |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10332 | 0-3 | PRP$ | denotes | Our |
T10333 | 4-8 | NNS | denotes | data |
T10334 | 9-13 | RB | denotes | thus |
T10335 | 14-23 | VBD | denotes | suggested |
T10336 | 24-28 | IN | denotes | that |
T10337 | 29-34 | JJ | denotes | IL-10 |
T10338 | 35-45 | NN | denotes | production |
T10339 | 46-48 | IN | denotes | by |
T10340 | 49-52 | JJ | denotes | Th1 |
T10341 | 53-58 | NNS | denotes | cells |
T10342 | 59-61 | IN | denotes | in |
T10343 | 62-70 | NN | denotes | response |
T10344 | 71-73 | TO | denotes | to |
T10345 | 74-78 | JJ | denotes | high |
T10346 | 79-86 | NN | denotes | antigen |
T10347 | 87-91 | NN | denotes | dose |
T10348 | 92-95 | CC | denotes | and |
T10349 | 96-101 | NN | denotes | IL-12 |
T10350 | 102-110 | VBZ | denotes | requires |
T10351 | 111-115 | CD | denotes | ERK1 |
T10352 | 116-119 | CC | denotes | and |
T10353 | 120-124 | CD | denotes | ERK2 |
T10354 | 125-134 | VBG | denotes | signaling |
T10355 | 134-135 | , | denotes | , |
T10356 | 136-139 | CC | denotes | but |
T10357 | 140-143 | RB | denotes | not |
T10358 | 144-147 | DT | denotes | the |
T10359 | 148-158 | NN | denotes | activation |
T10360 | 159-161 | IN | denotes | of |
T10361 | 162-165 | DT | denotes | the |
T10362 | 166-169 | CD | denotes | p38 |
T10363 | 170-172 | CC | denotes | or |
T10364 | 173-176 | DT | denotes | the |
T10365 | 177-182 | NNP | denotes | GSK3β |
T10366 | 183-191 | NNS | denotes | pathways |
T10367 | 191-192 | . | denotes | . |
R8070 | T10350 | T10335 | ccomp | requires,suggested |
R8071 | T10351 | T10350 | dobj | ERK1,requires |
R8072 | T10352 | T10351 | cc | and,ERK1 |
R8073 | T10353 | T10351 | conj | ERK2,ERK1 |
R8074 | T10354 | T10350 | advcl | signaling,requires |
R8075 | T10355 | T10354 | punct | ",",signaling |
R8076 | T10356 | T10354 | cc | but,signaling |
R8077 | T10357 | T10359 | neg | not,activation |
R8078 | T10358 | T10359 | det | the,activation |
R8079 | T10359 | T10354 | conj | activation,signaling |
R8080 | T10360 | T10359 | prep | of,activation |
R8081 | T10361 | T10362 | det | the,p38 |
R8082 | T10362 | T10360 | pobj | p38,of |
R8083 | T10363 | T10362 | cc | or,p38 |
R8084 | T10364 | T10366 | det | the,pathways |
R8085 | T10365 | T10366 | compound | GSK3β,pathways |
R8086 | T10366 | T10362 | conj | pathways,p38 |
R8087 | T10367 | T10335 | punct | .,suggested |
R8052 | T10332 | T10333 | poss | Our,data |
R8053 | T10333 | T10335 | nsubj | data,suggested |
R8054 | T10334 | T10335 | advmod | thus,suggested |
R8055 | T10335 | T10335 | ROOT | suggested,suggested |
R8056 | T10336 | T10350 | mark | that,requires |
R8057 | T10337 | T10338 | amod | IL-10,production |
R8058 | T10338 | T10350 | nsubj | production,requires |
R8059 | T10339 | T10338 | prep | by,production |
R8060 | T10340 | T10341 | amod | Th1,cells |
R8061 | T10341 | T10339 | pobj | cells,by |
R8062 | T10342 | T10338 | prep | in,production |
R8063 | T10343 | T10342 | pobj | response,in |
R8064 | T10344 | T10343 | prep | to,response |
R8065 | T10345 | T10347 | amod | high,dose |
R8066 | T10346 | T10347 | compound | antigen,dose |
R8067 | T10347 | T10344 | pobj | dose,to |
R8068 | T10348 | T10347 | cc | and,dose |
R8069 | T10349 | T10350 | nsubj | IL-12,requires |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10384 | 29-45 | http://purl.obolibrary.org/obo/GO_0032653 | denotes | IL-10 production |
T10389 | 29-45 | http://purl.obolibrary.org/obo/GO_0032613 | denotes | IL-10 production |
T10413 | 125-134 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
T10420 | 111-134 | http://purl.obolibrary.org/obo/GO_0070371 | denotes | ERK1 and ERK2 signaling |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10428 | 29-34 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
T10448 | 96-101 | http://purl.obolibrary.org/obo/GO_0005143 | denotes | IL-12 |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10462 | 53-58 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9391 | 0-192 | Sentence | denotes | Our data thus suggested that IL-10 production by Th1 cells in response to high antigen dose and IL-12 requires ERK1 and ERK2 signaling, but not the activation of the p38 or the GSK3β pathways. |
T92 | 0-192 | Sentence | denotes | Our data thus suggested that IL-10 production by Th1 cells in response to high antigen dose and IL-12 requires ERK1 and ERK2 signaling, but not the activation of the p38 or the GSK3β pathways. |
events-check-again
Id | Subject | Object | Predicate | Lexical cue | Negation | Speculation |
---|---|---|---|---|---|---|
T10785 | 29-34 | Protein | denotes | IL-10 | ||
T10786 | 35-45 | Gene_expression | denotes | production | ||
T10787 | 59-73 | Positive_regulation | denotes | in response to | ||
T10788 | 96-101 | Protein | denotes | IL-12 | ||
T10789 | 102-110 | Positive_regulation | denotes | requires | true | true |
T10790 | 102-110 | Positive_regulation | denotes | requires | true | true |
T10791 | 111-115 | Protein | denotes | ERK1 | ||
T10792 | 120-124 | Protein | denotes | ERK2 | ||
T10793 | 148-158 | Positive_regulation | denotes | activation | ||
T10794 | 148-158 | Positive_regulation | denotes | activation | ||
T10795 | 166-169 | Protein | denotes | p38 | ||
T10796 | 177-182 | Protein | denotes | GSK3β | ||
R8324 | T10785 | T10786 | themeOf | IL-10,production | ||
R8325 | T10786 | T10787 | themeOf | production,in response to | ||
R8326 | T10787 | T10789 | themeOf | in response to,requires | ||
R8327 | T10787 | T10790 | themeOf | in response to,requires | ||
R8328 | T10788 | T10787 | causeOf | IL-12,in response to | ||
R8331 | T10793 | T10789 | causeOf | activation,requires | ||
R8333 | T10794 | T10790 | causeOf | activation,requires | ||
R8335 | T10795 | T10793 | themeOf | p38,activation | ||
R8336 | T10796 | T10794 | themeOf | GSK3β,activation |
bionlp-st-ge-2016-reference-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10877 | 96-101 | Protein | denotes | IL-12 |
T10878 | 111-115 | Protein | denotes | ERK1 |
T10879 | 120-124 | Protein | denotes | ERK2 |
T10880 | 166-169 | Protein | denotes | p38 |
T10881 | 177-182 | Protein | denotes | GSK3β |
T10882 | 148-158 | Positive_regulation | denotes | activation |
T10883 | 148-158 | Positive_regulation | denotes | activation |
R8380 | T10880 | T10882 | themeOf | p38,activation |
R8381 | T10881 | T10883 | themeOf | GSK3β,activation |
test2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9259 | 29-34 | Protein | denotes | IL-10 |
T9260 | 35-45 | Gene_expression | denotes | production |
T9261 | 59-73 | Positive_regulation | denotes | in response to |
T9262 | 74-78 | Positive_regulation | denotes | high |
T9263 | 96-101 | Protein | denotes | IL-12 |
T9264 | 102-110 | Positive_regulation | denotes | requires |
T9265 | 111-115 | Protein | denotes | ERK1 |
T9266 | 120-124 | Protein | denotes | ERK2 |
T9267 | 148-158 | Positive_regulation | denotes | activation |
T9268 | 166-169 | Protein | denotes | p38 |
T9269 | 177-182 | Protein | denotes | GSK3β |
R7074 | T9259 | T9260 | themeOf | IL-10,production |
R7075 | T9260 | T9264 | themeOf | production,requires |
R7076 | T9260 | T9261 | themeOf | production,in response to |
R7077 | T9261 | T9264 | themeOf | in response to,requires |
R7078 | T9262 | T9261 | causeOf | high,in response to |
R7079 | T9263 | T9261 | causeOf | IL-12,in response to |
R7080 | T9267 | T9264 | causeOf | activation,requires |
R7081 | T9268 | T9267 | themeOf | p38,activation |
R7082 | T9269 | T9267 | themeOf | GSK3β,activation |