PMC:2728203 / 36227-37016 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2728203","sourcedb":"PMC","sourceid":"2728203","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2728203","text":"Fig. 2 Solution structure of the Nab2 N-terminal domain. (a) Ensemble view of the 45 accepted structures, showing all heavy atoms (superposed using the N, Cα, and C′ atoms of residues 4–99). The backbone and the majority of side chains are determined to high precision, with significant disorder being limited to the chain termini, a few surface side chains, and the loops between helices 1 and 2 and between helices 4 and 5. Structural statistics appear in Table 1. (b) A schematic illustration of the secondary structure of the N-terminal domain of Nab2. The fold of this domain is based on five α-helices (H1, red; H2, yellow; H3, green; H4, blue; and H5, purple) that pack to form a compact bundle. The arrangement of helices H1–H4 is analogous to that of the PWI fold30 (see Fig. 4).","divisions":[{"label":"label","span":{"begin":0,"end":6}}],"tracks":[]}