PMC:2724026 / 15487-15974 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2724026","sourcedb":"PMC","sourceid":"2724026","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2724026","text":"Formation of the central core was probed by nine mutations: H1, F101A, I104A; H2, L115M, L119M; H4, V141A, L145M, W148F; and H5, H160A, L161A. The extent of helix formation was probed by 13 Ala to Gly mutations: H1, A98G, A102G; H2, A113G, A114G, A117G; H4, A138G, A139G, A142G, A143G, A146G, A150G; and H5, A166G, S167G. (Note that in native FADD DD, H1 and H5 of the central core run parallel with each other and are packed orthogonally onto the parallel helix pair H2 and H4; Fig. 1).","tracks":[]}