PMC:2700745 / 54914-55640 JSONTXT

{"project":"2_test","denotations":[{"id":"19176218-16785447-100518411","span":{"begin":294,"end":298},"obj":"16785447"},{"id":"19176218-16785447-100518411","span":{"begin":294,"end":298},"obj":"16785447"},{"id":"19176218-16785447-3579350","span":{"begin":294,"end":298},"obj":"16785447"},{"id":"19176218-16785447-3579350","span":{"begin":294,"end":298},"obj":"16785447"}],"text":"The guinea pig has also been evaluated as a transmission model mammalian host for influenza virus. Guinea pigs were found to be highly susceptible to infection with the unadapted virus A/Panama/2007/99 (H3N2) virus, which replicated to high titers in the upper respiratory tract (Lowen et al., 2006). Although the animals did not sneeze or cough, virus was shed in nasal washings. In experiments performed at an ambient temperature of 20 °C and under low humidity, virus was transmitted from infected to non-infected guinea pigs housed either in the same cage, in an adjacent cage, or in a cage placed 91 cm away. Transmission appeared to be by droplet spread, and was more efficient at lower ambient temperature and humidity."}