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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2700745","sourcedb":"PMC","sourceid":"2700745","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2700745","text":"Recently Alarcon et al. (2007) demonstrated the use of the Brown Norway rat in evaluating influenza vaccines. Using microneedle technology for i.d. administration of three different types of influenza vaccines (Fluzone® 2003–2004 formulations and DNA plasmid-based vaccine) the investigators demonstrated in a rat model, that a whole inactivated virus elicited antibody responses to the corresponding wild type parent H3N2 and B strains. Animals treated with multiple doses of DNA plasmid vaccine also responded with antibody response to the parent strains.","tracks":[{"project":"2_test","denotations":[{"id":"19176218-17329444-3579172","span":{"begin":25,"end":29},"obj":"17329444"},{"id":"19176218-17329444-3579172","span":{"begin":25,"end":29},"obj":"17329444"},{"id":"T32499","span":{"begin":25,"end":29},"obj":"17329444"},{"id":"T97963","span":{"begin":25,"end":29},"obj":"17329444"}],"attributes":[{"subj":"19176218-17329444-3579172","pred":"source","obj":"2_test"},{"subj":"19176218-17329444-3579172","pred":"source","obj":"2_test"},{"subj":"T32499","pred":"source","obj":"2_test"},{"subj":"T97963","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#ec93cc","default":true}]}]}}