PMC:2678986 / 51433-52016 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2678986","sourcedb":"PMC","sourceid":"2678986","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2678986","text":"Table 2 A simple scheme to rank CSF-penetrating drugs or the CNS-penetration effectiveness (CPE) ranks, proposed by Letendre et al. (2008a). Rank based on the drug physicochemical characteristics, measured CSF concentrations and CNS efficacy data extracted from publicly available information.\nLow Intermediate High\nTenofovir (PMPA) Stavudine (d4T) Zidovudine (AZT)\nDidanosine (ddI) Lamivudine (3TC) Abacavir\nZalcitabine (ddC) Emtricitabine (FTC) Delavirdine\nNelfinavir Efavirenz Nevirapine\nRitonavir Amprenavir\nSaquinavir Fosamprenavir\nEnfuvirtide Atazanavir\nIndinavir","divisions":[{"label":"label","span":{"begin":0,"end":7}},{"label":"caption","span":{"begin":9,"end":294}},{"label":"p","span":{"begin":9,"end":294}},{"label":"tr","span":{"begin":295,"end":318}},{"label":"th","span":{"begin":295,"end":298}},{"label":"th","span":{"begin":300,"end":312}},{"label":"th","span":{"begin":314,"end":318}},{"label":"tr","span":{"begin":319,"end":370}},{"label":"td","span":{"begin":319,"end":335}},{"label":"td","span":{"begin":337,"end":352}},{"label":"td","span":{"begin":354,"end":370}},{"label":"tr","span":{"begin":371,"end":415}},{"label":"td","span":{"begin":371,"end":387}},{"label":"td","span":{"begin":389,"end":405}},{"label":"td","span":{"begin":407,"end":415}},{"label":"tr","span":{"begin":416,"end":467}},{"label":"td","span":{"begin":416,"end":433}},{"label":"td","span":{"begin":435,"end":454}},{"label":"td","span":{"begin":456,"end":467}},{"label":"tr","span":{"begin":468,"end":501}},{"label":"td","span":{"begin":468,"end":478}},{"label":"td","span":{"begin":480,"end":489}},{"label":"td","span":{"begin":491,"end":501}},{"label":"tr","span":{"begin":502,"end":523}},{"label":"td","span":{"begin":502,"end":511}},{"label":"td","span":{"begin":513,"end":523}},{"label":"tr","span":{"begin":524,"end":549}},{"label":"td","span":{"begin":524,"end":534}},{"label":"td","span":{"begin":536,"end":549}},{"label":"tr","span":{"begin":550,"end":573}},{"label":"td","span":{"begin":550,"end":561}},{"label":"td","span":{"begin":563,"end":573}}],"tracks":[]}