PMC:2678986 / 25544-26126
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2678986","sourcedb":"PMC","sourceid":"2678986","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2678986","text":"Anthonypillai et al. (2006) investigated the distribution of a prodrug of the NRTI tenofovir, known as PMPA to the brain, CSF and choroid plexus. Interestingly, the entry of this pro-drug into the brain was negligible, but it could reach the CSF. The presence of a transporter at the level of the choroid plexus was indicated. Since hOAT1 and hOAT3 are high- and low-affinity transporters of PMPA, respectively (Cihlar et al., 2001; Izzedine et al., 2005), the involvement of these carriers was speculated however no detectable interaction was observed (Anthonypillai et al., 2006).","tracks":[{"project":"2_test","denotations":[{"id":"19176219-16390539-3576984","span":{"begin":22,"end":26},"obj":"16390539"},{"id":"19176219-16390539-3576984","span":{"begin":22,"end":26},"obj":"16390539"},{"id":"19176219-11563082-99578354","span":{"begin":427,"end":431},"obj":"11563082"},{"id":"19176219-11563082-99578354","span":{"begin":427,"end":431},"obj":"11563082"},{"id":"19176219-15764850-99578355","span":{"begin":450,"end":454},"obj":"15764850"},{"id":"19176219-15764850-99578355","span":{"begin":450,"end":454},"obj":"15764850"},{"id":"19176219-16390539-99578356","span":{"begin":576,"end":580},"obj":"16390539"},{"id":"19176219-16390539-99578356","span":{"begin":576,"end":580},"obj":"16390539"},{"id":"T41621","span":{"begin":22,"end":26},"obj":"16390539"},{"id":"T68140","span":{"begin":22,"end":26},"obj":"16390539"},{"id":"19176219-15764850-3576985","span":{"begin":450,"end":454},"obj":"15764850"},{"id":"19176219-15764850-3576985","span":{"begin":450,"end":454},"obj":"15764850"},{"id":"19176219-16390539-3576986","span":{"begin":576,"end":580},"obj":"16390539"},{"id":"19176219-16390539-3576986","span":{"begin":576,"end":580},"obj":"16390539"}],"attributes":[{"subj":"19176219-16390539-3576984","pred":"source","obj":"2_test"},{"subj":"19176219-16390539-3576984","pred":"source","obj":"2_test"},{"subj":"19176219-11563082-99578354","pred":"source","obj":"2_test"},{"subj":"19176219-11563082-99578354","pred":"source","obj":"2_test"},{"subj":"19176219-15764850-99578355","pred":"source","obj":"2_test"},{"subj":"19176219-15764850-99578355","pred":"source","obj":"2_test"},{"subj":"19176219-16390539-99578356","pred":"source","obj":"2_test"},{"subj":"19176219-16390539-99578356","pred":"source","obj":"2_test"},{"subj":"T41621","pred":"source","obj":"2_test"},{"subj":"T68140","pred":"source","obj":"2_test"},{"subj":"19176219-15764850-3576985","pred":"source","obj":"2_test"},{"subj":"19176219-15764850-3576985","pred":"source","obj":"2_test"},{"subj":"19176219-16390539-3576986","pred":"source","obj":"2_test"},{"subj":"19176219-16390539-3576986","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#ece593","default":true}]}]}}