PMC:2675008 / 29366-30465
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2675008","sourcedb":"PMC","sourceid":"2675008","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2675008","text":"The first advice changed practice of oxytocin administration, but more recent case reports of hyponatraemia during labour imply that the second advice was forgotten.34,35 Hyponatraemia during labour, now less frequently iatrogenic, is more often caused by overdrinking.12–14,31 Our study was therefore designed to evaluate the prevalence of hyponatraemia during modern management of labour. The women in our study received oxytocin in moderate fluid volumes, and most of the fluids administered were orally ingested. Nonetheless, 21 women in our study developed hyponatraemia during labour, thus illustrating that the oral route of administration does not diminish the risks of excess water. As in other studies, we found hyponatraemia in women receiving oxytocin as well as epidural analgesia.1,6 The multivariate regression analysis performed in our study shows that hyponatraemia was probably caused by fluid intake, but only associated with oxytocin and epidural analgesia. Modern low-dose epidural regimens do usually not call for large volumes of intravenous fluids to preserve blood pressure.","tracks":[{"project":"2_test","denotations":[{"id":"19175600-17925046-7908421","span":{"begin":165,"end":167},"obj":"17925046"},{"id":"19175600-18162206-7908422","span":{"begin":168,"end":170},"obj":"18162206"},{"id":"19175600-12200908-7908423","span":{"begin":269,"end":271},"obj":"12200908"},{"id":"19175600-15569290-7908423","span":{"begin":269,"end":271},"obj":"15569290"},{"id":"19175600-15598305-7908423","span":{"begin":269,"end":271},"obj":"15598305"},{"id":"19175600-15663123-7908424","span":{"begin":275,"end":277},"obj":"15663123"},{"id":"19175600-6790112-7908425","span":{"begin":794,"end":795},"obj":"6790112"},{"id":"19175600-7657008-7908426","span":{"begin":796,"end":797},"obj":"7657008"}],"attributes":[{"subj":"19175600-17925046-7908421","pred":"source","obj":"2_test"},{"subj":"19175600-18162206-7908422","pred":"source","obj":"2_test"},{"subj":"19175600-12200908-7908423","pred":"source","obj":"2_test"},{"subj":"19175600-15569290-7908423","pred":"source","obj":"2_test"},{"subj":"19175600-15598305-7908423","pred":"source","obj":"2_test"},{"subj":"19175600-15663123-7908424","pred":"source","obj":"2_test"},{"subj":"19175600-6790112-7908425","pred":"source","obj":"2_test"},{"subj":"19175600-7657008-7908426","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#93ecb2","default":true}]}]}}